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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
EBNOGNPH_00001	6.82e-73	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_00002	2.95e-239	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBNOGNPH_00003	1.79e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EBNOGNPH_00004	1.06e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
EBNOGNPH_00005	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
EBNOGNPH_00006	1.51e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
EBNOGNPH_00007	1.12e-210	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBNOGNPH_00008	1.13e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EBNOGNPH_00009	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
EBNOGNPH_00010	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
EBNOGNPH_00011	4.15e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EBNOGNPH_00012	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EBNOGNPH_00013	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EBNOGNPH_00014	1.25e-165	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
EBNOGNPH_00015	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
EBNOGNPH_00016	3.84e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
EBNOGNPH_00017	4.12e-50	-	-	-	-	-	-	-	-
EBNOGNPH_00018	0.0	ydaO	-	-	E	-	-	-	amino acid
EBNOGNPH_00019	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EBNOGNPH_00020	1.15e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBNOGNPH_00021	8.05e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EBNOGNPH_00022	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
EBNOGNPH_00023	1.04e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EBNOGNPH_00024	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
EBNOGNPH_00025	6.3e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
EBNOGNPH_00026	2.69e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
EBNOGNPH_00027	2.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBNOGNPH_00028	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
EBNOGNPH_00029	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EBNOGNPH_00030	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EBNOGNPH_00031	1.32e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EBNOGNPH_00032	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
EBNOGNPH_00033	1.86e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
EBNOGNPH_00034	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBNOGNPH_00035	4.39e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBNOGNPH_00036	1.32e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
EBNOGNPH_00037	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EBNOGNPH_00039	3.65e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBNOGNPH_00040	7.57e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
EBNOGNPH_00041	1.13e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
EBNOGNPH_00042	1.61e-274	arcT	-	-	E	-	-	-	Aminotransferase
EBNOGNPH_00043	2.8e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
EBNOGNPH_00044	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
EBNOGNPH_00045	3.45e-305	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
EBNOGNPH_00046	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
EBNOGNPH_00047	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBNOGNPH_00048	1.35e-203	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
EBNOGNPH_00049	8.55e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EBNOGNPH_00050	1.67e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EBNOGNPH_00051	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBNOGNPH_00052	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EBNOGNPH_00053	4.02e-189	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
EBNOGNPH_00054	3.3e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EBNOGNPH_00055	2.03e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
EBNOGNPH_00056	5.8e-248	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EBNOGNPH_00057	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
EBNOGNPH_00058	2.41e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBNOGNPH_00059	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
EBNOGNPH_00060	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EBNOGNPH_00061	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBNOGNPH_00062	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EBNOGNPH_00064	3.69e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EBNOGNPH_00065	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
EBNOGNPH_00066	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBNOGNPH_00067	8.93e-250	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBNOGNPH_00068	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EBNOGNPH_00070	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
EBNOGNPH_00071	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBNOGNPH_00072	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EBNOGNPH_00073	4.17e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
EBNOGNPH_00074	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
EBNOGNPH_00075	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EBNOGNPH_00076	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBNOGNPH_00077	3.15e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
EBNOGNPH_00078	2.78e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EBNOGNPH_00079	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBNOGNPH_00080	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
EBNOGNPH_00081	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EBNOGNPH_00082	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EBNOGNPH_00083	5.57e-135	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
EBNOGNPH_00084	3.52e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBNOGNPH_00085	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EBNOGNPH_00086	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EBNOGNPH_00087	9.63e-130	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
EBNOGNPH_00088	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBNOGNPH_00089	1.84e-262	yacL	-	-	S	-	-	-	domain protein
EBNOGNPH_00090	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EBNOGNPH_00091	3.55e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
EBNOGNPH_00092	6.52e-73	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
EBNOGNPH_00093	3.53e-158	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EBNOGNPH_00094	3.45e-144	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
EBNOGNPH_00095	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
EBNOGNPH_00096	3.23e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EBNOGNPH_00097	1.11e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EBNOGNPH_00098	1.25e-212	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
EBNOGNPH_00099	4.54e-241	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
EBNOGNPH_00100	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
EBNOGNPH_00102	8.15e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
EBNOGNPH_00103	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
EBNOGNPH_00104	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EBNOGNPH_00105	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBNOGNPH_00106	8.7e-166	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
EBNOGNPH_00107	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
EBNOGNPH_00108	1.39e-150	-	-	-	-	-	-	-	-
EBNOGNPH_00111	9.6e-212	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EBNOGNPH_00112	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
EBNOGNPH_00113	2.99e-242	-	-	-	D	-	-	-	nuclear chromosome segregation
EBNOGNPH_00117	3.91e-31	-	-	-	-	-	-	-	-
EBNOGNPH_00118	3.17e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EBNOGNPH_00119	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
EBNOGNPH_00120	0.0	-	-	-	EGP	-	-	-	Major Facilitator
EBNOGNPH_00121	1.15e-127	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
EBNOGNPH_00122	3.23e-64	-	-	-	-	-	-	-	-
EBNOGNPH_00123	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBNOGNPH_00124	3.78e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EBNOGNPH_00125	4.39e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EBNOGNPH_00126	3.57e-164	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
EBNOGNPH_00127	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
EBNOGNPH_00128	9.88e-57	-	-	-	-	-	-	-	-
EBNOGNPH_00129	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
EBNOGNPH_00130	2.84e-82	-	-	-	S	-	-	-	Domain of unknown function DUF302
EBNOGNPH_00131	1.98e-200	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBNOGNPH_00132	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
EBNOGNPH_00133	2.01e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EBNOGNPH_00134	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
EBNOGNPH_00135	4.64e-240	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EBNOGNPH_00136	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
EBNOGNPH_00137	9.92e-143	-	-	-	-	-	-	-	-
EBNOGNPH_00138	6.39e-235	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
EBNOGNPH_00139	4.99e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EBNOGNPH_00140	9.96e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBNOGNPH_00141	6.44e-122	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EBNOGNPH_00142	1.13e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
EBNOGNPH_00143	4.09e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
EBNOGNPH_00144	5.55e-137	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
EBNOGNPH_00145	2.98e-257	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
EBNOGNPH_00147	4.86e-53	-	-	-	-	-	-	-	-
EBNOGNPH_00149	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
EBNOGNPH_00150	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
EBNOGNPH_00151	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
EBNOGNPH_00152	2.59e-230	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
EBNOGNPH_00153	3.63e-195	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EBNOGNPH_00155	4.29e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
EBNOGNPH_00156	3.68e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00157	6.32e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
EBNOGNPH_00158	1.92e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EBNOGNPH_00159	1.68e-76	-	-	-	S	-	-	-	Small secreted protein
EBNOGNPH_00160	1.79e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
EBNOGNPH_00161	1.11e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EBNOGNPH_00162	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
EBNOGNPH_00163	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
EBNOGNPH_00164	2.17e-21	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
EBNOGNPH_00165	3e-71	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EBNOGNPH_00167	3.03e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
EBNOGNPH_00169	8.27e-80	-	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_00170	1.28e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EBNOGNPH_00171	9.46e-199	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EBNOGNPH_00173	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
EBNOGNPH_00174	2.44e-24	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EBNOGNPH_00175	3.66e-53	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
EBNOGNPH_00176	1e-104	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
EBNOGNPH_00177	7.06e-63	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
EBNOGNPH_00178	4.74e-125	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_00179	2.56e-151	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
EBNOGNPH_00181	5.93e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
EBNOGNPH_00182	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
EBNOGNPH_00183	2.18e-106	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EBNOGNPH_00184	4.37e-106	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EBNOGNPH_00185	1.1e-50	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_00186	2.23e-101	yphH	-	-	S	-	-	-	Cupin domain
EBNOGNPH_00187	4.35e-30	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
EBNOGNPH_00188	2.55e-214	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_00189	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
EBNOGNPH_00192	1.9e-230	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBNOGNPH_00193	1.31e-59	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_00194	3.36e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EBNOGNPH_00196	4.82e-72	-	-	-	-	-	-	-	-
EBNOGNPH_00197	1.26e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
EBNOGNPH_00198	2.48e-173	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EBNOGNPH_00199	4.23e-76	-	-	-	-	-	-	-	-
EBNOGNPH_00200	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBNOGNPH_00201	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EBNOGNPH_00202	5.22e-111	-	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_00203	1.98e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EBNOGNPH_00204	7.3e-268	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
EBNOGNPH_00206	3.6e-77	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
EBNOGNPH_00207	1.03e-59	yxeL	-	-	K	-	-	-	acetyltransferase
EBNOGNPH_00208	1.2e-98	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
EBNOGNPH_00209	2.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
EBNOGNPH_00210	3.45e-184	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
EBNOGNPH_00211	3.62e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
EBNOGNPH_00212	2.16e-108	-	-	-	S	-	-	-	MmgE/PrpD family
EBNOGNPH_00214	1.96e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
EBNOGNPH_00215	1.32e-146	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
EBNOGNPH_00216	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00217	7.45e-197	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
EBNOGNPH_00218	5.44e-176	-	-	-	IQ	-	-	-	KR domain
EBNOGNPH_00219	7.89e-269	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
EBNOGNPH_00220	1.58e-202	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
EBNOGNPH_00221	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
EBNOGNPH_00222	4.79e-222	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
EBNOGNPH_00223	3.92e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
EBNOGNPH_00224	3.13e-226	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
EBNOGNPH_00225	4.43e-250	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
EBNOGNPH_00226	1.39e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
EBNOGNPH_00227	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EBNOGNPH_00228	1.1e-165	-	-	-	F	-	-	-	glutamine amidotransferase
EBNOGNPH_00229	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
EBNOGNPH_00230	1.52e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
EBNOGNPH_00231	1.75e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
EBNOGNPH_00232	8.34e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EBNOGNPH_00233	5.17e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
EBNOGNPH_00234	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EBNOGNPH_00235	1.85e-200	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
EBNOGNPH_00236	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
EBNOGNPH_00237	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
EBNOGNPH_00238	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EBNOGNPH_00239	1.21e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EBNOGNPH_00240	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBNOGNPH_00241	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
EBNOGNPH_00242	2.28e-117	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
EBNOGNPH_00243	4.54e-87	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EBNOGNPH_00244	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_00245	1.74e-177	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
EBNOGNPH_00246	6.71e-21	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00247	6.22e-136	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_00248	1.71e-62	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00249	1.71e-31	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_00251	2.01e-20	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
EBNOGNPH_00254	2.62e-202	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EBNOGNPH_00255	1.54e-248	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EBNOGNPH_00256	3.63e-136	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EBNOGNPH_00257	2.04e-194	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EBNOGNPH_00258	5.14e-210	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
EBNOGNPH_00259	3.44e-99	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EBNOGNPH_00260	4.43e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EBNOGNPH_00261	7.37e-42	-	-	-	V	ko:K07011	-	ko00000	Glycosyl transferase, family 2
EBNOGNPH_00263	4.05e-90	-	-	-	M	-	-	-	Glycosyl transferase 4-like
EBNOGNPH_00264	1.91e-99	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EBNOGNPH_00265	4.03e-09	lsgF	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
EBNOGNPH_00266	1.04e-121	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
EBNOGNPH_00267	9.56e-166	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
EBNOGNPH_00268	1.14e-177	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
EBNOGNPH_00269	3.35e-147	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
EBNOGNPH_00270	4.76e-170	epsB	-	-	M	-	-	-	biosynthesis protein
EBNOGNPH_00271	8.54e-223	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EBNOGNPH_00272	5.72e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EBNOGNPH_00273	9.67e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
EBNOGNPH_00274	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EBNOGNPH_00275	1.47e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
EBNOGNPH_00276	2.15e-188	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EBNOGNPH_00277	1.34e-208	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EBNOGNPH_00278	2.9e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
EBNOGNPH_00279	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
EBNOGNPH_00280	1.8e-271	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
EBNOGNPH_00281	1.38e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EBNOGNPH_00282	1.1e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00283	3.27e-287	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EBNOGNPH_00285	4.91e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EBNOGNPH_00287	3.66e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBNOGNPH_00288	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
EBNOGNPH_00289	3.68e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EBNOGNPH_00290	2.32e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
EBNOGNPH_00291	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBNOGNPH_00292	1.07e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
EBNOGNPH_00293	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBNOGNPH_00294	7.62e-307	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EBNOGNPH_00295	2.67e-155	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
EBNOGNPH_00296	2e-24	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EBNOGNPH_00300	3.85e-197	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
EBNOGNPH_00301	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
EBNOGNPH_00302	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_00303	4.4e-163	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_00304	1.38e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2813)
EBNOGNPH_00305	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_00306	2.02e-153	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EBNOGNPH_00307	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_00308	3.22e-156	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_00309	4.32e-71	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
EBNOGNPH_00310	2e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EBNOGNPH_00311	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EBNOGNPH_00312	2.14e-278	-	-	-	G	-	-	-	Transporter, major facilitator family protein
EBNOGNPH_00313	1.25e-263	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
EBNOGNPH_00314	4.58e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EBNOGNPH_00315	9.99e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EBNOGNPH_00316	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
EBNOGNPH_00317	1.9e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
EBNOGNPH_00318	1.27e-228	-	-	-	K	-	-	-	WYL domain
EBNOGNPH_00319	3.96e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
EBNOGNPH_00320	1.29e-45	-	-	-	-	-	-	-	-
EBNOGNPH_00323	3.76e-84	-	-	-	-	-	-	-	-
EBNOGNPH_00324	3.5e-145	yicL	-	-	EG	-	-	-	EamA-like transporter family
EBNOGNPH_00325	4.39e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
EBNOGNPH_00326	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EBNOGNPH_00327	4.85e-98	-	-	-	K	-	-	-	LysR substrate binding domain
EBNOGNPH_00328	2.53e-65	-	-	-	K	-	-	-	LysR substrate binding domain
EBNOGNPH_00329	3.46e-207	rssA	-	-	S	-	-	-	Phospholipase, patatin family
EBNOGNPH_00330	5.4e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
EBNOGNPH_00331	3.14e-237	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
EBNOGNPH_00332	1.2e-158	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EBNOGNPH_00333	8.23e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
EBNOGNPH_00334	1.67e-249	flp	-	-	V	-	-	-	Beta-lactamase
EBNOGNPH_00335	1.95e-291	-	-	-	-	-	-	-	-
EBNOGNPH_00337	7.52e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EBNOGNPH_00338	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBNOGNPH_00339	4.23e-213	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
EBNOGNPH_00340	3.89e-209	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
EBNOGNPH_00341	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EBNOGNPH_00343	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
EBNOGNPH_00345	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBNOGNPH_00346	7.83e-304	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
EBNOGNPH_00347	6.92e-56	-	-	-	S	-	-	-	SNARE associated Golgi protein
EBNOGNPH_00348	3.37e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
EBNOGNPH_00349	8.39e-127	-	-	-	K	-	-	-	Virulence activator alpha C-term
EBNOGNPH_00351	8.26e-57	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_00352	3.88e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_00353	1.27e-39	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EBNOGNPH_00354	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_00355	1.06e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00356	6.22e-243	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
EBNOGNPH_00357	9.32e-16	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_00359	7.6e-188	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_00360	1.53e-38	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00361	1.12e-98	mleR	-	-	K	-	-	-	LysR family
EBNOGNPH_00362	1.08e-289	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
EBNOGNPH_00363	4.73e-232	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
EBNOGNPH_00364	1.01e-116	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EBNOGNPH_00365	3.78e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EBNOGNPH_00366	7.85e-271	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EBNOGNPH_00367	7.13e-288	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
EBNOGNPH_00368	2.63e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
EBNOGNPH_00369	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
EBNOGNPH_00370	6.93e-155	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
EBNOGNPH_00371	1.92e-241	-	-	-	I	-	-	-	Alpha beta
EBNOGNPH_00372	7.04e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
EBNOGNPH_00373	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBNOGNPH_00375	1.8e-218	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EBNOGNPH_00376	2.13e-188	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
EBNOGNPH_00377	2.85e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
EBNOGNPH_00378	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EBNOGNPH_00379	3.98e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
EBNOGNPH_00380	1.15e-77	-	-	-	-	-	-	-	-
EBNOGNPH_00381	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EBNOGNPH_00382	1.08e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EBNOGNPH_00383	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
EBNOGNPH_00384	1.01e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EBNOGNPH_00385	3.87e-141	-	-	-	S	-	-	-	VIT family
EBNOGNPH_00386	5.34e-150	-	-	-	S	-	-	-	membrane
EBNOGNPH_00387	7.54e-210	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
EBNOGNPH_00388	2.24e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
EBNOGNPH_00389	5.79e-39	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
EBNOGNPH_00390	1.36e-161	-	-	-	S	-	-	-	Putative threonine/serine exporter
EBNOGNPH_00391	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
EBNOGNPH_00392	3.13e-149	-	-	-	I	-	-	-	phosphatase
EBNOGNPH_00393	1.2e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EBNOGNPH_00395	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
EBNOGNPH_00396	4.69e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
EBNOGNPH_00402	2.84e-79	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_00403	6.38e-100	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
EBNOGNPH_00405	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_00407	1.08e-30	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
EBNOGNPH_00408	3.37e-272	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EBNOGNPH_00409	5.03e-239	-	-	-	S	-	-	-	interspecies interaction between organisms
EBNOGNPH_00410	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
EBNOGNPH_00411	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBNOGNPH_00412	8.08e-188	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EBNOGNPH_00413	1.6e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBNOGNPH_00414	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBNOGNPH_00415	1.23e-192	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBNOGNPH_00416	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
EBNOGNPH_00417	3.48e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBNOGNPH_00418	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBNOGNPH_00419	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBNOGNPH_00420	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
EBNOGNPH_00421	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBNOGNPH_00422	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EBNOGNPH_00423	7.83e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EBNOGNPH_00424	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EBNOGNPH_00425	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
EBNOGNPH_00426	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBNOGNPH_00427	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EBNOGNPH_00428	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EBNOGNPH_00429	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EBNOGNPH_00430	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBNOGNPH_00431	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EBNOGNPH_00432	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBNOGNPH_00433	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBNOGNPH_00434	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBNOGNPH_00435	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
EBNOGNPH_00436	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBNOGNPH_00437	3.43e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EBNOGNPH_00438	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBNOGNPH_00439	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EBNOGNPH_00440	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBNOGNPH_00441	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EBNOGNPH_00442	1.56e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
EBNOGNPH_00443	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EBNOGNPH_00444	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
EBNOGNPH_00445	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EBNOGNPH_00446	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EBNOGNPH_00447	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBNOGNPH_00448	2.5e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
EBNOGNPH_00449	3.02e-275	-	-	-	-	-	-	-	-
EBNOGNPH_00450	2.92e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
EBNOGNPH_00451	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBNOGNPH_00452	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBNOGNPH_00453	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EBNOGNPH_00454	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EBNOGNPH_00455	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
EBNOGNPH_00456	1.37e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
EBNOGNPH_00457	4.57e-124	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_00458	3.67e-99	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
EBNOGNPH_00459	3.02e-61	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_00460	1.49e-152	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EBNOGNPH_00462	9.56e-44	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00463	5.63e-38	-	-	-	E	-	-	-	IrrE N-terminal-like domain
EBNOGNPH_00464	2.26e-109	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
EBNOGNPH_00465	1.52e-307	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
EBNOGNPH_00466	2.76e-155	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
EBNOGNPH_00467	2.21e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
EBNOGNPH_00468	4.36e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EBNOGNPH_00469	1.97e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
EBNOGNPH_00470	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
EBNOGNPH_00471	3.06e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
EBNOGNPH_00472	6.86e-176	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
EBNOGNPH_00473	2.67e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
EBNOGNPH_00474	3.14e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
EBNOGNPH_00475	4.14e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBNOGNPH_00476	1.38e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
EBNOGNPH_00477	6.51e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EBNOGNPH_00478	7.73e-185	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EBNOGNPH_00479	1.17e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
EBNOGNPH_00480	4.84e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
EBNOGNPH_00481	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EBNOGNPH_00482	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EBNOGNPH_00483	6.58e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
EBNOGNPH_00484	1.68e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBNOGNPH_00485	2.87e-263	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EBNOGNPH_00486	1.49e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EBNOGNPH_00487	4.36e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
EBNOGNPH_00488	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EBNOGNPH_00489	5.2e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
EBNOGNPH_00490	6.7e-283	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
EBNOGNPH_00491	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
EBNOGNPH_00492	5.5e-67	ylxQ	-	-	J	-	-	-	ribosomal protein
EBNOGNPH_00493	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBNOGNPH_00494	4.99e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EBNOGNPH_00495	1.31e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EBNOGNPH_00496	2.41e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
EBNOGNPH_00497	1.17e-315	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EBNOGNPH_00498	1.05e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00499	1.54e-156	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_00500	1.54e-43	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_00501	5.16e-48	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_00502	1.25e-179	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
EBNOGNPH_00503	3.26e-46	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EBNOGNPH_00507	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
EBNOGNPH_00508	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EBNOGNPH_00509	4.42e-307	yycH	-	-	S	-	-	-	YycH protein
EBNOGNPH_00510	2.05e-185	yycI	-	-	S	-	-	-	YycH protein
EBNOGNPH_00511	4.51e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
EBNOGNPH_00512	9.52e-270	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
EBNOGNPH_00513	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBNOGNPH_00514	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_00515	2.68e-224	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
EBNOGNPH_00516	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EBNOGNPH_00517	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
EBNOGNPH_00518	7.69e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
EBNOGNPH_00519	2.56e-143	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
EBNOGNPH_00520	2.97e-244	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EBNOGNPH_00521	2.32e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
EBNOGNPH_00522	1.97e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBNOGNPH_00523	3.41e-278	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EBNOGNPH_00524	1.15e-47	-	-	-	-	-	-	-	-
EBNOGNPH_00525	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
EBNOGNPH_00526	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBNOGNPH_00527	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EBNOGNPH_00528	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
EBNOGNPH_00529	2.37e-190	-	-	-	C	-	-	-	Aldo keto reductase
EBNOGNPH_00530	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
EBNOGNPH_00531	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
EBNOGNPH_00532	7.49e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
EBNOGNPH_00533	1.88e-165	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EBNOGNPH_00534	4.91e-56	-	-	-	K	-	-	-	transcriptional regulator
EBNOGNPH_00535	1.25e-135	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_00537	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
EBNOGNPH_00538	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00539	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
EBNOGNPH_00540	1.31e-245	ampC	-	-	V	-	-	-	Beta-lactamase
EBNOGNPH_00541	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBNOGNPH_00542	2.31e-63	-	-	-	-	-	-	-	-
EBNOGNPH_00543	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
EBNOGNPH_00544	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
EBNOGNPH_00545	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
EBNOGNPH_00546	1.53e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBNOGNPH_00547	1.92e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EBNOGNPH_00548	2.77e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EBNOGNPH_00549	9e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBNOGNPH_00550	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EBNOGNPH_00551	8.52e-254	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
EBNOGNPH_00552	2.72e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
EBNOGNPH_00553	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
EBNOGNPH_00554	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
EBNOGNPH_00555	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBNOGNPH_00556	6.18e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBNOGNPH_00557	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBNOGNPH_00558	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBNOGNPH_00559	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBNOGNPH_00560	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBNOGNPH_00561	2.8e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
EBNOGNPH_00562	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
EBNOGNPH_00563	9.77e-278	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EBNOGNPH_00564	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
EBNOGNPH_00565	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
EBNOGNPH_00566	2.95e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
EBNOGNPH_00568	9.42e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
EBNOGNPH_00569	5.85e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
EBNOGNPH_00570	1.9e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EBNOGNPH_00571	5e-106	uspA	-	-	T	-	-	-	universal stress protein
EBNOGNPH_00573	4.72e-301	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
EBNOGNPH_00574	1.97e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EBNOGNPH_00575	9.16e-100	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
EBNOGNPH_00578	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_00579	7.62e-60	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EBNOGNPH_00583	7.77e-19	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
EBNOGNPH_00584	6.25e-07	ydiL	-	-	S	ko:K07052	-	ko00000	protease
EBNOGNPH_00588	2.33e-33	-	-	-	M	-	-	-	CHAP domain
EBNOGNPH_00590	4.18e-228	-	-	-	U	-	-	-	type IV secretory pathway VirB4
EBNOGNPH_00591	1.95e-27	-	-	-	-	-	-	-	-
EBNOGNPH_00594	7.63e-59	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
EBNOGNPH_00596	6.3e-75	-	-	-	-	-	-	-	-
EBNOGNPH_00597	9.64e-269	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
EBNOGNPH_00601	2.11e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
EBNOGNPH_00604	8.53e-168	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
EBNOGNPH_00605	1.64e-65	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
EBNOGNPH_00614	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_00615	8.33e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_00616	1.94e-139	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_00617	4.95e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EBNOGNPH_00618	5.87e-231	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EBNOGNPH_00619	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EBNOGNPH_00620	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EBNOGNPH_00621	3.68e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EBNOGNPH_00622	5.45e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EBNOGNPH_00623	1.81e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBNOGNPH_00624	7.71e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EBNOGNPH_00625	9.79e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EBNOGNPH_00626	1.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBNOGNPH_00627	3.38e-293	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
EBNOGNPH_00628	2.29e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
EBNOGNPH_00629	3.4e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
EBNOGNPH_00630	4.2e-202	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EBNOGNPH_00631	1.07e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
EBNOGNPH_00633	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
EBNOGNPH_00634	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
EBNOGNPH_00635	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
EBNOGNPH_00636	7.32e-176	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
EBNOGNPH_00637	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EBNOGNPH_00638	1.18e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBNOGNPH_00639	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBNOGNPH_00640	1.44e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EBNOGNPH_00641	4.78e-111	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EBNOGNPH_00642	3.83e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
EBNOGNPH_00643	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
EBNOGNPH_00644	4.37e-76	-	-	-	M	-	-	-	Lysin motif
EBNOGNPH_00645	5.63e-154	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
EBNOGNPH_00646	4.63e-275	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
EBNOGNPH_00647	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
EBNOGNPH_00648	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EBNOGNPH_00649	2.52e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
EBNOGNPH_00650	1.06e-210	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
EBNOGNPH_00651	1.86e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EBNOGNPH_00652	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00653	5.32e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EBNOGNPH_00654	2.55e-121	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EBNOGNPH_00655	8.06e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
EBNOGNPH_00656	1.34e-197	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
EBNOGNPH_00657	9.77e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
EBNOGNPH_00658	1.4e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
EBNOGNPH_00659	2.46e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
EBNOGNPH_00660	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
EBNOGNPH_00661	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
EBNOGNPH_00662	1.03e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EBNOGNPH_00663	8.69e-182	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBNOGNPH_00664	2.55e-212	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
EBNOGNPH_00665	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBNOGNPH_00666	2.24e-198	-	-	-	D	-	-	-	DNA integration
EBNOGNPH_00667	9.3e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
EBNOGNPH_00668	5.26e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EBNOGNPH_00669	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EBNOGNPH_00670	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EBNOGNPH_00671	2.53e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
EBNOGNPH_00672	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
EBNOGNPH_00673	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
EBNOGNPH_00674	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
EBNOGNPH_00675	3.75e-100	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
EBNOGNPH_00676	1.99e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
EBNOGNPH_00677	2.93e-313	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
EBNOGNPH_00678	3.6e-305	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
EBNOGNPH_00679	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
EBNOGNPH_00681	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
EBNOGNPH_00682	2.79e-154	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
EBNOGNPH_00683	4.3e-312	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
EBNOGNPH_00685	3.57e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EBNOGNPH_00686	4.34e-25	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EBNOGNPH_00687	4.99e-27	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_00688	3.82e-23	-	-	-	-	-	-	-	-
EBNOGNPH_00689	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EBNOGNPH_00690	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
EBNOGNPH_00691	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EBNOGNPH_00692	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EBNOGNPH_00693	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
EBNOGNPH_00694	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EBNOGNPH_00695	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
EBNOGNPH_00696	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EBNOGNPH_00697	1.1e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EBNOGNPH_00698	2.36e-139	-	-	-	-	-	-	-	-
EBNOGNPH_00699	4.52e-175	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBNOGNPH_00700	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
EBNOGNPH_00701	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
EBNOGNPH_00702	6.43e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EBNOGNPH_00703	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EBNOGNPH_00704	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
EBNOGNPH_00705	1.88e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EBNOGNPH_00706	2.4e-151	ybbR	-	-	S	-	-	-	YbbR-like protein
EBNOGNPH_00707	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBNOGNPH_00708	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EBNOGNPH_00709	2.55e-68	-	-	-	-	-	-	-	-
EBNOGNPH_00710	1.02e-263	oatA	-	-	I	-	-	-	Acyltransferase
EBNOGNPH_00711	7.18e-195	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EBNOGNPH_00712	7.87e-112	lytE	-	-	M	-	-	-	Lysin motif
EBNOGNPH_00713	5.72e-221	-	-	-	S	-	-	-	Conserved hypothetical protein 698
EBNOGNPH_00714	4.74e-213	-	-	-	K	-	-	-	LysR substrate binding domain
EBNOGNPH_00715	2.97e-164	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
EBNOGNPH_00716	7.71e-192	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
EBNOGNPH_00717	8.77e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
EBNOGNPH_00718	1.5e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
EBNOGNPH_00719	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
EBNOGNPH_00720	2.38e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
EBNOGNPH_00721	1.37e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
EBNOGNPH_00722	1.8e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
EBNOGNPH_00723	4.39e-136	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_00724	2.18e-136	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_00727	5.92e-58	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_00728	1.53e-30	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
EBNOGNPH_00729	1.07e-50	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
EBNOGNPH_00730	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EBNOGNPH_00731	1.15e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
EBNOGNPH_00732	9.97e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EBNOGNPH_00733	1.15e-299	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EBNOGNPH_00734	3.41e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EBNOGNPH_00735	5.34e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
EBNOGNPH_00736	1.84e-68	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
EBNOGNPH_00738	3.97e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00739	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EBNOGNPH_00740	3.82e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBNOGNPH_00741	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EBNOGNPH_00742	1.3e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
EBNOGNPH_00743	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
EBNOGNPH_00744	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EBNOGNPH_00745	2.73e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
EBNOGNPH_00746	7.82e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBNOGNPH_00747	6.41e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
EBNOGNPH_00748	3.54e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
EBNOGNPH_00749	2.7e-126	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
EBNOGNPH_00750	1.93e-28	-	-	-	S	-	-	-	Protein conserved in bacteria
EBNOGNPH_00751	3.03e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
EBNOGNPH_00752	4.48e-67	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
EBNOGNPH_00753	2.47e-13	-	-	-	K	-	-	-	transcriptional
EBNOGNPH_00754	1.75e-253	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
EBNOGNPH_00755	7.95e-153	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
EBNOGNPH_00756	4.11e-134	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
EBNOGNPH_00758	1.41e-192	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_00759	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
EBNOGNPH_00761	1.73e-17	-	-	-	S	-	-	-	CHY zinc finger
EBNOGNPH_00763	0.000604	-	-	-	M	-	-	-	domain, Protein
EBNOGNPH_00764	1.05e-65	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_00766	1.21e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EBNOGNPH_00767	1.98e-123	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EBNOGNPH_00768	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
EBNOGNPH_00769	6.12e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
EBNOGNPH_00770	9.91e-302	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EBNOGNPH_00771	7.69e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBNOGNPH_00772	1.89e-78	-	-	-	-	-	-	-	-
EBNOGNPH_00773	1.01e-184	yidA	-	-	S	-	-	-	hydrolase
EBNOGNPH_00774	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
EBNOGNPH_00775	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
EBNOGNPH_00776	2.16e-97	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EBNOGNPH_00777	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EBNOGNPH_00778	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBNOGNPH_00779	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
EBNOGNPH_00780	2.38e-36	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
EBNOGNPH_00781	5.38e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
EBNOGNPH_00782	1.49e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBNOGNPH_00783	9.6e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
EBNOGNPH_00784	1.9e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
EBNOGNPH_00785	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EBNOGNPH_00786	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EBNOGNPH_00787	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EBNOGNPH_00788	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EBNOGNPH_00789	2.89e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
EBNOGNPH_00790	3.71e-147	-	-	-	S	-	-	-	(CBS) domain
EBNOGNPH_00791	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EBNOGNPH_00792	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBNOGNPH_00793	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
EBNOGNPH_00794	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
EBNOGNPH_00795	1.65e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
EBNOGNPH_00796	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EBNOGNPH_00797	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
EBNOGNPH_00798	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBNOGNPH_00799	4.35e-30	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
EBNOGNPH_00800	9.68e-57	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_00801	1.06e-244	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EBNOGNPH_00802	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
EBNOGNPH_00803	9.72e-229	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EBNOGNPH_00804	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
EBNOGNPH_00805	7.25e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EBNOGNPH_00806	1.2e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
EBNOGNPH_00807	8.31e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
EBNOGNPH_00808	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
EBNOGNPH_00809	1.73e-48	-	-	-	-	-	-	-	-
EBNOGNPH_00810	2.05e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_00811	3.51e-154	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
EBNOGNPH_00812	1.09e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
EBNOGNPH_00813	9.08e-71	-	-	-	-	-	-	-	-
EBNOGNPH_00814	1.72e-216	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBNOGNPH_00815	3.64e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EBNOGNPH_00816	8.79e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
EBNOGNPH_00817	2.44e-120	ymdB	-	-	S	-	-	-	Macro domain protein
EBNOGNPH_00818	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
EBNOGNPH_00819	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
EBNOGNPH_00820	1.41e-59	-	-	-	-	-	-	-	-
EBNOGNPH_00821	2.5e-270	-	-	-	S	-	-	-	Putative metallopeptidase domain
EBNOGNPH_00822	1.35e-261	-	-	-	S	-	-	-	associated with various cellular activities
EBNOGNPH_00823	2e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
EBNOGNPH_00824	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
EBNOGNPH_00826	1.34e-160	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
EBNOGNPH_00827	2.15e-73	-	-	-	-	-	-	-	-
EBNOGNPH_00828	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EBNOGNPH_00829	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBNOGNPH_00830	9.74e-138	-	-	-	-	-	-	-	-
EBNOGNPH_00831	1.11e-35	-	-	-	-	-	-	-	-
EBNOGNPH_00832	2.46e-217	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
EBNOGNPH_00833	3.29e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EBNOGNPH_00834	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
EBNOGNPH_00835	2.84e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
EBNOGNPH_00836	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
EBNOGNPH_00837	5.81e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EBNOGNPH_00838	7.13e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EBNOGNPH_00839	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EBNOGNPH_00840	1.45e-223	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
EBNOGNPH_00841	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
EBNOGNPH_00842	7.87e-119	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
EBNOGNPH_00843	4.87e-19	-	-	-	IQ	-	-	-	Dehydrogenase
EBNOGNPH_00844	1.89e-36	-	-	-	IQ	-	-	-	Dehydrogenase
EBNOGNPH_00845	0.000155	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EBNOGNPH_00846	1.91e-05	ytcD	-	-	K	-	-	-	HxlR-like helix-turn-helix
EBNOGNPH_00847	1.51e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
EBNOGNPH_00848	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBNOGNPH_00849	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBNOGNPH_00850	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBNOGNPH_00851	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EBNOGNPH_00852	1.13e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
EBNOGNPH_00853	1.32e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBNOGNPH_00854	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
EBNOGNPH_00855	9.6e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
EBNOGNPH_00856	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EBNOGNPH_00857	4.04e-285	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EBNOGNPH_00858	1.43e-226	-	-	-	-	-	-	-	-
EBNOGNPH_00859	3.07e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
EBNOGNPH_00860	1.33e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
EBNOGNPH_00861	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
EBNOGNPH_00862	2.22e-37	-	-	-	EGP	-	-	-	Major Facilitator
EBNOGNPH_00863	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
EBNOGNPH_00864	6.79e-183	-	-	-	EG	-	-	-	EamA-like transporter family
EBNOGNPH_00865	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
EBNOGNPH_00866	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
EBNOGNPH_00867	3.62e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EBNOGNPH_00868	3.8e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EBNOGNPH_00869	4.31e-182	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EBNOGNPH_00870	5.1e-219	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBNOGNPH_00871	7.04e-77	-	-	-	S	-	-	-	Flavodoxin
EBNOGNPH_00872	7.91e-95	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
EBNOGNPH_00873	2.34e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
EBNOGNPH_00874	4.09e-250	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBNOGNPH_00875	2.31e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
EBNOGNPH_00876	3.92e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EBNOGNPH_00877	4.73e-210	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
EBNOGNPH_00878	3.55e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EBNOGNPH_00880	3.49e-217	-	-	-	H	-	-	-	geranyltranstransferase activity
EBNOGNPH_00881	8.42e-236	-	-	-	-	-	-	-	-
EBNOGNPH_00882	1.99e-53	-	-	-	-	-	-	-	-
EBNOGNPH_00883	1.83e-150	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
EBNOGNPH_00884	2.81e-240	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
EBNOGNPH_00885	8.62e-102	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	GAF domain
EBNOGNPH_00886	6.94e-54	-	-	-	-	-	-	-	-
EBNOGNPH_00887	1.44e-127	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EBNOGNPH_00888	1.11e-107	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EBNOGNPH_00889	5.2e-294	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
EBNOGNPH_00890	8.88e-112	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
EBNOGNPH_00891	1.03e-242	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
EBNOGNPH_00892	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EBNOGNPH_00893	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
EBNOGNPH_00894	2.15e-132	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
EBNOGNPH_00895	7.16e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
EBNOGNPH_00896	1.58e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_00897	7.69e-36	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_00898	9.21e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
EBNOGNPH_00899	3.69e-31	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
EBNOGNPH_00900	5.23e-235	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
EBNOGNPH_00901	4.35e-247	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
EBNOGNPH_00903	2.29e-96	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
EBNOGNPH_00904	3.19e-115	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
EBNOGNPH_00905	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
EBNOGNPH_00906	1.28e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
EBNOGNPH_00907	1.03e-120	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
EBNOGNPH_00908	1.17e-152	-	-	-	Q	-	-	-	Methyltransferase domain
EBNOGNPH_00910	7.52e-131	-	-	-	S	-	-	-	CAAX protease self-immunity
EBNOGNPH_00911	2.95e-127	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EBNOGNPH_00912	1.71e-59	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EBNOGNPH_00913	1.3e-79	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EBNOGNPH_00914	2.39e-131	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EBNOGNPH_00915	1.68e-277	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EBNOGNPH_00916	2.2e-136	-	-	-	-	-	-	-	-
EBNOGNPH_00917	1.76e-113	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
EBNOGNPH_00918	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
EBNOGNPH_00919	2.89e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
EBNOGNPH_00920	2.58e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EBNOGNPH_00921	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
EBNOGNPH_00922	3.04e-204	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EBNOGNPH_00923	3.12e-135	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
EBNOGNPH_00924	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
EBNOGNPH_00925	4.94e-244	mocA	-	-	S	-	-	-	Oxidoreductase
EBNOGNPH_00926	1.42e-305	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
EBNOGNPH_00928	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
EBNOGNPH_00929	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
EBNOGNPH_00930	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
EBNOGNPH_00931	9.09e-91	XK27_08315	-	-	M	-	-	-	Sulfatase
EBNOGNPH_00932	1.59e-24	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EBNOGNPH_00933	3.52e-83	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EBNOGNPH_00934	5.29e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EBNOGNPH_00935	4.08e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
EBNOGNPH_00936	3.68e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
EBNOGNPH_00937	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
EBNOGNPH_00938	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
EBNOGNPH_00939	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
EBNOGNPH_00940	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
EBNOGNPH_00941	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
EBNOGNPH_00942	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
EBNOGNPH_00943	5.75e-244	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
EBNOGNPH_00944	6.64e-205	-	-	-	EG	-	-	-	EamA-like transporter family
EBNOGNPH_00945	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
EBNOGNPH_00946	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EBNOGNPH_00947	1.79e-143	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
EBNOGNPH_00948	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EBNOGNPH_00949	0.0	fusA1	-	-	J	-	-	-	elongation factor G
EBNOGNPH_00950	1.78e-270	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
EBNOGNPH_00951	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
EBNOGNPH_00952	4.48e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
EBNOGNPH_00953	6.87e-19	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
EBNOGNPH_00954	7.05e-132	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
EBNOGNPH_00955	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
EBNOGNPH_00957	5.21e-99	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
EBNOGNPH_00958	0.0	-	-	-	M	-	-	-	domain protein
EBNOGNPH_00959	8.23e-23	-	2.1.1.303	-	K	ko:K04096,ko:K20421	ko01059,ko01130,map01059,map01130	ko00000,ko00001,ko00002,ko01000	DNA-binding transcription factor activity
EBNOGNPH_00960	0.0	-	-	-	L	-	-	-	Recombinase
EBNOGNPH_00961	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
EBNOGNPH_00962	3.04e-48	-	-	-	-	-	-	-	-
EBNOGNPH_00963	3.19e-186	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EBNOGNPH_00964	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
EBNOGNPH_00965	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
EBNOGNPH_00966	3.08e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EBNOGNPH_00967	1.58e-282	-	-	-	S	-	-	-	Phage capsid family
EBNOGNPH_00968	4.66e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
EBNOGNPH_00969	5.82e-311	-	-	-	S	-	-	-	Phage portal protein
EBNOGNPH_00970	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
EBNOGNPH_00971	9.81e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
EBNOGNPH_00972	2.03e-128	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EBNOGNPH_00973	1.56e-297	-	-	-	KL	-	-	-	DNA methylase
EBNOGNPH_00974	1.87e-92	-	-	-	-	-	-	-	-
EBNOGNPH_00975	1.45e-112	-	-	-	-	-	-	-	-
EBNOGNPH_00976	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
EBNOGNPH_00977	8.74e-62	-	-	-	S	-	-	-	VRR_NUC
EBNOGNPH_00978	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
EBNOGNPH_00979	3.05e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EBNOGNPH_00980	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
EBNOGNPH_00981	5.25e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
EBNOGNPH_00982	3.34e-266	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
EBNOGNPH_00983	4.21e-54	-	-	-	-	-	-	-	-
EBNOGNPH_00984	9.27e-32	-	-	-	-	-	-	-	-
EBNOGNPH_00985	1.83e-91	-	-	-	K	-	-	-	DNA-templated transcription, initiation
EBNOGNPH_00987	5.39e-137	-	-	-	L	-	-	-	Dead deah box helicase domain protein
EBNOGNPH_00988	9.51e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
EBNOGNPH_00989	5.89e-231	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EBNOGNPH_00990	1.77e-260	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
EBNOGNPH_00991	6.15e-78	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EBNOGNPH_00992	6.95e-301	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
EBNOGNPH_00993	2.6e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
EBNOGNPH_00994	1.85e-105	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
EBNOGNPH_00995	4.84e-215	yvgN	-	-	C	-	-	-	Aldo keto reductase
EBNOGNPH_00996	3.41e-205	-	-	-	S	-	-	-	DUF218 domain
EBNOGNPH_00998	3.31e-125	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
EBNOGNPH_00999	2.58e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EBNOGNPH_01000	8.47e-152	-	-	-	S	-	-	-	Phage minor capsid protein 2
EBNOGNPH_01003	5.42e-276	-	-	-	E	-	-	-	Aminotransferase
EBNOGNPH_01004	5.9e-159	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
EBNOGNPH_01005	1.33e-41	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
EBNOGNPH_01006	1.09e-315	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
EBNOGNPH_01007	2.67e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
EBNOGNPH_01008	9.33e-96	-	-	-	S	-	-	-	Fic/DOC family
EBNOGNPH_01009	1.59e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
EBNOGNPH_01010	4.45e-140	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
EBNOGNPH_01011	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
EBNOGNPH_01012	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
EBNOGNPH_01013	1.96e-151	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
EBNOGNPH_01014	6.4e-197	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
EBNOGNPH_01015	1.04e-35	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EBNOGNPH_01016	5.32e-44	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EBNOGNPH_01017	8.55e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EBNOGNPH_01018	2.26e-61	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_01019	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBNOGNPH_01020	9.06e-279	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
EBNOGNPH_01021	1.35e-92	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBNOGNPH_01022	1.95e-249	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
EBNOGNPH_01023	5.39e-272	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBNOGNPH_01024	3.06e-14	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
EBNOGNPH_01025	4.99e-273	-	-	-	G	-	-	-	Major Facilitator Superfamily
EBNOGNPH_01027	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
EBNOGNPH_01030	1.51e-194	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
EBNOGNPH_01031	9.36e-154	-	-	-	GM	-	-	-	NAD(P)H-binding
EBNOGNPH_01032	1.2e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
EBNOGNPH_01033	5.61e-301	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
EBNOGNPH_01035	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
EBNOGNPH_01036	4.37e-68	-	-	-	-	-	-	-	-
EBNOGNPH_01037	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
EBNOGNPH_01039	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EBNOGNPH_01040	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
EBNOGNPH_01041	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
EBNOGNPH_01042	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EBNOGNPH_01043	1.77e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EBNOGNPH_01044	8.22e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EBNOGNPH_01045	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBNOGNPH_01046	1.53e-214	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
EBNOGNPH_01047	5.06e-201	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
EBNOGNPH_01048	5.15e-271	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
EBNOGNPH_01049	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
EBNOGNPH_01050	5.38e-273	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
EBNOGNPH_01051	5.18e-17	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
EBNOGNPH_01052	2.06e-68	lysR	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_01053	1.23e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
EBNOGNPH_01054	2.03e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
EBNOGNPH_01055	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
EBNOGNPH_01056	1.73e-275	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EBNOGNPH_01057	7.41e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
EBNOGNPH_01058	1.99e-231	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
EBNOGNPH_01059	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
EBNOGNPH_01060	7.76e-72	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
EBNOGNPH_01061	6.93e-158	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
EBNOGNPH_01062	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
EBNOGNPH_01063	1.77e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
EBNOGNPH_01064	4.02e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EBNOGNPH_01065	8.44e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EBNOGNPH_01066	5.05e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
EBNOGNPH_01067	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EBNOGNPH_01068	2.15e-163	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
EBNOGNPH_01069	3.81e-127	-	-	-	-	-	-	-	-
EBNOGNPH_01070	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
EBNOGNPH_01071	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
EBNOGNPH_01072	6.4e-123	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
EBNOGNPH_01073	3.96e-63	-	-	-	C	-	-	-	Flavodoxin
EBNOGNPH_01074	1.24e-54	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
EBNOGNPH_01075	1.17e-61	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EBNOGNPH_01076	3.16e-13	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EBNOGNPH_01077	3.44e-152	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
EBNOGNPH_01078	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EBNOGNPH_01079	8.46e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
EBNOGNPH_01080	2.57e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EBNOGNPH_01081	1.27e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBNOGNPH_01082	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
EBNOGNPH_01083	3.77e-93	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
EBNOGNPH_01084	3.33e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
EBNOGNPH_01085	1.77e-201	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
EBNOGNPH_01086	1.43e-153	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EBNOGNPH_01087	6.44e-22	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EBNOGNPH_01088	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_01089	1.9e-39	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_01090	6.15e-161	-	-	-	S	-	-	-	Membrane
EBNOGNPH_01091	3.18e-299	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EBNOGNPH_01092	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
EBNOGNPH_01093	1.01e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EBNOGNPH_01094	1.05e-177	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBNOGNPH_01095	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
EBNOGNPH_01096	3.03e-106	usp5	-	-	T	-	-	-	universal stress protein
EBNOGNPH_01097	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EBNOGNPH_01098	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBNOGNPH_01099	1.03e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
EBNOGNPH_01100	1.49e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
EBNOGNPH_01101	3.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
EBNOGNPH_01102	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
EBNOGNPH_01103	3.54e-116	-	-	-	GM	-	-	-	epimerase
EBNOGNPH_01104	1.99e-111	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
EBNOGNPH_01105	1.77e-197	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
EBNOGNPH_01106	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EBNOGNPH_01107	3.78e-167	-	-	-	-	-	-	-	-
EBNOGNPH_01108	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBNOGNPH_01109	3.81e-169	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
EBNOGNPH_01110	4.33e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EBNOGNPH_01111	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
EBNOGNPH_01112	6.7e-81	-	-	-	-	-	-	-	-
EBNOGNPH_01113	3.46e-244	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EBNOGNPH_01114	9.76e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBNOGNPH_01115	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
EBNOGNPH_01116	2.45e-267	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EBNOGNPH_01117	1.46e-71	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EBNOGNPH_01118	2.15e-11	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EBNOGNPH_01119	5.02e-124	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EBNOGNPH_01120	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBNOGNPH_01121	1.25e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
EBNOGNPH_01122	1.56e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBNOGNPH_01123	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EBNOGNPH_01125	3.72e-145	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
EBNOGNPH_01126	4.92e-141	-	-	-	C	-	-	-	aldo keto reductase
EBNOGNPH_01127	5.9e-258	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBNOGNPH_01128	2.07e-282	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBNOGNPH_01129	0.0	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
EBNOGNPH_01130	2.75e-103	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
EBNOGNPH_01131	1.14e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EBNOGNPH_01132	6.78e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EBNOGNPH_01133	1.52e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
EBNOGNPH_01134	1.19e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBNOGNPH_01135	2.01e-70	-	-	-	C	-	-	-	FMN binding
EBNOGNPH_01136	1.11e-77	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
EBNOGNPH_01137	8.34e-66	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
EBNOGNPH_01138	6.85e-34	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
EBNOGNPH_01139	5.63e-15	-	-	-	U	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03110	Preprotein translocase subunit SecB
EBNOGNPH_01143	1.51e-30	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
EBNOGNPH_01144	3.65e-45	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma-70 factor, region 1.1
EBNOGNPH_01147	3.1e-100	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
EBNOGNPH_01157	1.81e-17	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EBNOGNPH_01171	2.1e-06	-	-	-	S	-	-	-	sequence-specific DNA binding
EBNOGNPH_01173	1.8e-112	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EBNOGNPH_01176	4.72e-128	-	-	-	-	-	-	-	-
EBNOGNPH_01177	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
EBNOGNPH_01178	1.15e-234	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
EBNOGNPH_01180	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EBNOGNPH_01181	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EBNOGNPH_01182	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EBNOGNPH_01183	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
EBNOGNPH_01184	4.35e-284	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
EBNOGNPH_01185	1.77e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EBNOGNPH_01186	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EBNOGNPH_01187	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBNOGNPH_01188	3.03e-197	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
EBNOGNPH_01189	1.43e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EBNOGNPH_01190	2.64e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EBNOGNPH_01191	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
EBNOGNPH_01193	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EBNOGNPH_01194	3.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EBNOGNPH_01195	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
EBNOGNPH_01196	6.14e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBNOGNPH_01197	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBNOGNPH_01198	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBNOGNPH_01199	1.82e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
EBNOGNPH_01200	1.55e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
EBNOGNPH_01201	5.05e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBNOGNPH_01202	4.01e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EBNOGNPH_01203	4.53e-127	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBNOGNPH_01204	3.92e-50	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
EBNOGNPH_01205	4.88e-88	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
EBNOGNPH_01206	6.81e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EBNOGNPH_01207	4.64e-142	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EBNOGNPH_01208	1.56e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EBNOGNPH_01209	1.01e-179	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EBNOGNPH_01210	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBNOGNPH_01211	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EBNOGNPH_01212	8.7e-116	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EBNOGNPH_01213	4.85e-46	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EBNOGNPH_01214	6.7e-43	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
EBNOGNPH_01216	6.69e-42	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
EBNOGNPH_01217	1.51e-71	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_01218	3.27e-49	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
EBNOGNPH_01219	9.78e-273	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
EBNOGNPH_01220	3.29e-73	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EBNOGNPH_01222	3.64e-193	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
EBNOGNPH_01223	1.8e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EBNOGNPH_01224	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
EBNOGNPH_01225	5.37e-72	-	-	-	S	-	-	-	MazG-like family
EBNOGNPH_01226	7.6e-139	-	-	-	I	-	-	-	PAP2 superfamily
EBNOGNPH_01227	6.08e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
EBNOGNPH_01228	7.4e-126	-	-	-	-	-	-	-	-
EBNOGNPH_01229	2.97e-286	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EBNOGNPH_01230	9.26e-218	-	-	-	V	-	-	-	Beta-lactamase enzyme family
EBNOGNPH_01231	0.0	potE	-	-	E	-	-	-	Amino Acid
EBNOGNPH_01233	2.74e-144	-	-	-	-	-	-	-	-
EBNOGNPH_01234	1.11e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
EBNOGNPH_01235	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
EBNOGNPH_01236	5.06e-234	-	-	-	-	-	-	-	-
EBNOGNPH_01237	1.01e-99	-	-	-	-	-	-	-	-
EBNOGNPH_01238	3.79e-83	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EBNOGNPH_01239	5.17e-60	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
EBNOGNPH_01240	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
EBNOGNPH_01241	1.69e-124	-	-	-	V	-	-	-	VanZ like family
EBNOGNPH_01242	2.95e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
EBNOGNPH_01243	2.74e-81	-	-	-	-	-	-	-	-
EBNOGNPH_01244	1.39e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
EBNOGNPH_01245	9.52e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
EBNOGNPH_01246	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
EBNOGNPH_01247	1.37e-218	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
EBNOGNPH_01249	5.17e-100	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
EBNOGNPH_01250	5.15e-246	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
EBNOGNPH_01251	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
EBNOGNPH_01252	2.36e-215	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
EBNOGNPH_01253	2.67e-109	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EBNOGNPH_01254	5.63e-312	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EBNOGNPH_01255	6.35e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
EBNOGNPH_01256	3.68e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EBNOGNPH_01257	2e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EBNOGNPH_01258	2.71e-197	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EBNOGNPH_01259	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
EBNOGNPH_01260	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EBNOGNPH_01261	3.97e-62	-	-	-	-	-	-	-	-
EBNOGNPH_01262	7.45e-25	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
EBNOGNPH_01263	6.19e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EBNOGNPH_01264	2.38e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EBNOGNPH_01265	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EBNOGNPH_01266	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EBNOGNPH_01267	3.88e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBNOGNPH_01268	2.81e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EBNOGNPH_01269	8.19e-50	-	-	-	K	-	-	-	transcriptional regulator
EBNOGNPH_01270	1.82e-71	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EBNOGNPH_01271	3.36e-124	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
EBNOGNPH_01272	5.78e-10	-	-	-	-	-	-	-	-
EBNOGNPH_01273	1.72e-215	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
EBNOGNPH_01274	8.5e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
EBNOGNPH_01275	2.37e-225	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
EBNOGNPH_01276	0.0	-	-	-	-	-	-	-	-
EBNOGNPH_01277	9.76e-229	-	-	-	M	-	-	-	Glycosyl transferase family 2
EBNOGNPH_01278	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EBNOGNPH_01279	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
EBNOGNPH_01280	3.98e-229	-	-	-	S	-	-	-	Glycosyltransferase like family 2
EBNOGNPH_01281	5.14e-217	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EBNOGNPH_01282	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
EBNOGNPH_01283	1.64e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01285	1.14e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
EBNOGNPH_01286	9.75e-232	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBNOGNPH_01287	3.81e-255	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
EBNOGNPH_01288	5.62e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
EBNOGNPH_01289	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBNOGNPH_01290	2.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
EBNOGNPH_01291	2.41e-07	-	-	-	-	-	-	-	-
EBNOGNPH_01292	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
EBNOGNPH_01293	5.03e-166	-	-	-	F	-	-	-	NUDIX domain
EBNOGNPH_01294	8.61e-143	pncA	-	-	Q	-	-	-	Isochorismatase family
EBNOGNPH_01295	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBNOGNPH_01296	8.07e-126	-	-	-	S	-	-	-	Pfam:DUF3816
EBNOGNPH_01297	1.15e-182	-	-	-	G	-	-	-	MucBP domain
EBNOGNPH_01298	2.02e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EBNOGNPH_01299	1.81e-207	-	-	-	EG	-	-	-	EamA-like transporter family
EBNOGNPH_01300	6.84e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
EBNOGNPH_01302	6.41e-60	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_01305	1.27e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EBNOGNPH_01306	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EBNOGNPH_01307	2.46e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
EBNOGNPH_01308	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
EBNOGNPH_01309	1.34e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
EBNOGNPH_01310	1.37e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
EBNOGNPH_01311	2.59e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
EBNOGNPH_01312	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
EBNOGNPH_01313	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01314	2.73e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
EBNOGNPH_01315	1.91e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
EBNOGNPH_01316	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
EBNOGNPH_01317	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
EBNOGNPH_01318	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBNOGNPH_01319	1.62e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
EBNOGNPH_01320	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBNOGNPH_01321	2.27e-305	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
EBNOGNPH_01322	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EBNOGNPH_01323	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBNOGNPH_01324	8.79e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EBNOGNPH_01325	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EBNOGNPH_01326	4.41e-226	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
EBNOGNPH_01327	1.11e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
EBNOGNPH_01328	3.41e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
EBNOGNPH_01329	1.7e-300	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EBNOGNPH_01330	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBNOGNPH_01331	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
EBNOGNPH_01332	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBNOGNPH_01333	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
EBNOGNPH_01334	3.2e-211	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBNOGNPH_01335	2.23e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
EBNOGNPH_01336	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EBNOGNPH_01337	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EBNOGNPH_01338	2.64e-286	-	-	-	P	-	-	-	Chloride transporter, ClC family
EBNOGNPH_01339	3.39e-121	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
EBNOGNPH_01340	5.24e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
EBNOGNPH_01341	2.65e-140	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EBNOGNPH_01342	3.33e-123	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
EBNOGNPH_01343	1.75e-193	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EBNOGNPH_01344	3.54e-199	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
EBNOGNPH_01345	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EBNOGNPH_01346	4.62e-92	-	-	-	-	-	-	-	-
EBNOGNPH_01347	1.08e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
EBNOGNPH_01348	5.94e-238	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
EBNOGNPH_01349	6.95e-182	-	-	-	-	-	-	-	-
EBNOGNPH_01350	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
EBNOGNPH_01351	5.53e-112	-	-	-	M	-	-	-	PFAM NLP P60 protein
EBNOGNPH_01352	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
EBNOGNPH_01353	1.94e-73	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
EBNOGNPH_01354	1.09e-227	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
EBNOGNPH_01355	2.13e-212	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
EBNOGNPH_01356	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
EBNOGNPH_01361	2.15e-203	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
EBNOGNPH_01362	9.57e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EBNOGNPH_01363	2.73e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EBNOGNPH_01364	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
EBNOGNPH_01365	1.01e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EBNOGNPH_01366	9.59e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
EBNOGNPH_01367	2.38e-141	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
EBNOGNPH_01368	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
EBNOGNPH_01369	2e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
EBNOGNPH_01370	7.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
EBNOGNPH_01371	5.07e-261	-	-	-	-	-	-	-	-
EBNOGNPH_01372	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EBNOGNPH_01373	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EBNOGNPH_01375	1.24e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
EBNOGNPH_01376	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EBNOGNPH_01377	4.18e-176	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EBNOGNPH_01378	4.57e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EBNOGNPH_01379	9.72e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
EBNOGNPH_01380	2.55e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EBNOGNPH_01381	5.7e-199	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
EBNOGNPH_01382	4.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EBNOGNPH_01383	1.29e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_01384	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
EBNOGNPH_01385	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
EBNOGNPH_01386	2.07e-281	-	-	-	G	-	-	-	Major Facilitator
EBNOGNPH_01387	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
EBNOGNPH_01388	7.37e-106	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
EBNOGNPH_01389	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
EBNOGNPH_01390	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
EBNOGNPH_01391	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EBNOGNPH_01392	9.01e-276	xylR	-	-	GK	-	-	-	ROK family
EBNOGNPH_01393	1.44e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
EBNOGNPH_01394	0.0	yclK	-	-	T	-	-	-	Histidine kinase
EBNOGNPH_01395	1.39e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
EBNOGNPH_01398	0.0	potE	-	-	E	-	-	-	Amino Acid
EBNOGNPH_01399	1.65e-241	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
EBNOGNPH_01400	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
EBNOGNPH_01401	6.06e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBNOGNPH_01402	1.74e-254	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
EBNOGNPH_01403	2.05e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EBNOGNPH_01404	3.49e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
EBNOGNPH_01405	1.59e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBNOGNPH_01406	8.61e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EBNOGNPH_01407	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
EBNOGNPH_01408	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBNOGNPH_01411	2.77e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01412	3.76e-193	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EBNOGNPH_01413	3.41e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
EBNOGNPH_01414	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
EBNOGNPH_01415	3.86e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
EBNOGNPH_01417	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
EBNOGNPH_01418	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
EBNOGNPH_01419	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBNOGNPH_01420	6.52e-218	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
EBNOGNPH_01421	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
EBNOGNPH_01422	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
EBNOGNPH_01423	2.33e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
EBNOGNPH_01424	3.89e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EBNOGNPH_01425	7.47e-280	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBNOGNPH_01426	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
EBNOGNPH_01427	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBNOGNPH_01428	2.8e-226	camS	-	-	S	-	-	-	sex pheromone
EBNOGNPH_01429	6.72e-63	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBNOGNPH_01430	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EBNOGNPH_01431	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBNOGNPH_01432	2.52e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
EBNOGNPH_01433	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EBNOGNPH_01434	4.04e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EBNOGNPH_01435	3.57e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EBNOGNPH_01436	7.92e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EBNOGNPH_01437	1.9e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
EBNOGNPH_01438	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBNOGNPH_01439	4.74e-207	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
EBNOGNPH_01440	2.38e-272	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
EBNOGNPH_01441	2.7e-164	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
EBNOGNPH_01442	9.16e-240	-	-	-	-	-	-	-	-
EBNOGNPH_01443	5.79e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
EBNOGNPH_01444	7.95e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EBNOGNPH_01445	0.0	-	-	-	L	-	-	-	DNA helicase
EBNOGNPH_01446	1.48e-117	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
EBNOGNPH_01447	2.79e-102	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EBNOGNPH_01448	1.47e-111	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
EBNOGNPH_01449	5.54e-97	-	-	-	M	-	-	-	LysM domain protein
EBNOGNPH_01450	1.31e-250	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
EBNOGNPH_01451	1.85e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
EBNOGNPH_01452	1.03e-206	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
EBNOGNPH_01453	4.25e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EBNOGNPH_01454	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
EBNOGNPH_01455	1.11e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
EBNOGNPH_01456	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
EBNOGNPH_01457	5.89e-20	ebrB	-	-	U	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
EBNOGNPH_01458	8.21e-07	-	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_01469	2.03e-250	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
EBNOGNPH_01470	9.78e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EBNOGNPH_01471	6.53e-131	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
EBNOGNPH_01472	6.61e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01473	1.8e-138	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EBNOGNPH_01474	2.84e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
EBNOGNPH_01475	2.96e-100	ywnA	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_01476	2.13e-96	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
EBNOGNPH_01477	2.36e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
EBNOGNPH_01478	2.68e-32	-	-	-	C	-	-	-	Flavodoxin
EBNOGNPH_01479	1.3e-85	-	-	-	GM	-	-	-	NmrA-like family
EBNOGNPH_01480	5.59e-39	-	-	-	GM	-	-	-	NmrA-like family
EBNOGNPH_01481	9.22e-59	-	-	-	K	-	-	-	transcriptional regulator
EBNOGNPH_01482	3.77e-139	-	-	-	L	-	-	-	Integrase
EBNOGNPH_01483	3.5e-87	-	-	-	I	-	-	-	Alpha/beta hydrolase family
EBNOGNPH_01484	2.24e-58	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EBNOGNPH_01485	3.23e-91	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EBNOGNPH_01486	4.1e-48	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
EBNOGNPH_01487	9.16e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
EBNOGNPH_01488	1.22e-17	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_01489	6.38e-74	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EBNOGNPH_01490	1.16e-47	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EBNOGNPH_01491	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EBNOGNPH_01500	2.97e-121	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
EBNOGNPH_01501	9.06e-193	-	-	-	L	-	-	-	DNA replication protein
EBNOGNPH_01504	6.95e-11	-	-	-	S	-	-	-	Helix-turn-helix domain
EBNOGNPH_01505	2.22e-216	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EBNOGNPH_01506	6.54e-251	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EBNOGNPH_01507	1.96e-158	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_01508	3e-118	-	-	-	P	-	-	-	Cadmium resistance transporter
EBNOGNPH_01509	5.11e-93	gmT1	-	-	EG	-	-	-	EamA-like transporter family
EBNOGNPH_01510	9.11e-237	-	-	-	M	-	-	-	Iron Transport-associated domain
EBNOGNPH_01511	3.24e-130	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
EBNOGNPH_01512	7.99e-196	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
EBNOGNPH_01513	2.57e-200	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBNOGNPH_01514	4.45e-181	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01515	9.56e-303	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
EBNOGNPH_01516	5.93e-26	-	-	-	-	-	-	-	-
EBNOGNPH_01517	1.3e-50	-	-	-	-	-	-	-	-
EBNOGNPH_01518	6.97e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
EBNOGNPH_01519	2.6e-153	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EBNOGNPH_01520	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EBNOGNPH_01521	4.03e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
EBNOGNPH_01522	8.97e-95	-	-	-	F	-	-	-	Nudix hydrolase
EBNOGNPH_01523	9.61e-137	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
EBNOGNPH_01524	1.47e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
EBNOGNPH_01525	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
EBNOGNPH_01526	7.87e-214	-	-	-	-	-	-	-	-
EBNOGNPH_01527	9.7e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
EBNOGNPH_01528	4.94e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
EBNOGNPH_01529	3.12e-313	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
EBNOGNPH_01530	4.58e-114	-	-	-	K	-	-	-	FR47-like protein
EBNOGNPH_01531	0.0	-	-	-	E	-	-	-	amino acid
EBNOGNPH_01532	4.15e-172	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
EBNOGNPH_01533	5.33e-267	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EBNOGNPH_01534	2.06e-297	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBNOGNPH_01535	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
EBNOGNPH_01536	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
EBNOGNPH_01537	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
EBNOGNPH_01538	9.54e-205	-	-	-	EG	-	-	-	EamA-like transporter family
EBNOGNPH_01539	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EBNOGNPH_01540	1.05e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
EBNOGNPH_01541	2.8e-135	-	-	-	K	-	-	-	acetyltransferase
EBNOGNPH_01542	5.39e-222	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
EBNOGNPH_01543	5.13e-165	sptS	-	-	T	-	-	-	Histidine kinase
EBNOGNPH_01544	1.35e-100	dltr	-	-	K	-	-	-	response regulator
EBNOGNPH_01545	1.16e-146	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
EBNOGNPH_01546	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
EBNOGNPH_01547	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
EBNOGNPH_01548	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
EBNOGNPH_01549	5.61e-110	-	-	-	-	-	-	-	-
EBNOGNPH_01550	2.37e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
EBNOGNPH_01551	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
EBNOGNPH_01552	4.42e-221	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
EBNOGNPH_01553	1.1e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
EBNOGNPH_01554	3.22e-98	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
EBNOGNPH_01555	1.22e-70	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
EBNOGNPH_01556	7.44e-281	-	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
EBNOGNPH_01557	8.31e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EBNOGNPH_01558	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01559	2.97e-77	-	-	-	S	-	-	-	FMN_bind
EBNOGNPH_01560	9.1e-205	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
EBNOGNPH_01561	7.74e-29	XK27_06785	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EBNOGNPH_01562	4.59e-133	-	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_01563	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBNOGNPH_01564	4.13e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
EBNOGNPH_01565	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
EBNOGNPH_01566	2.74e-68	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
EBNOGNPH_01567	7.23e-200	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
EBNOGNPH_01568	3.35e-14	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EBNOGNPH_01569	6.62e-13	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EBNOGNPH_01570	2.91e-52	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EBNOGNPH_01571	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
EBNOGNPH_01572	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EBNOGNPH_01574	1.43e-21	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EBNOGNPH_01576	1.12e-157	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EBNOGNPH_01578	4.89e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
EBNOGNPH_01579	1.54e-52	-	-	-	-	-	-	-	-
EBNOGNPH_01580	4.95e-217	-	-	-	GK	-	-	-	ROK family
EBNOGNPH_01581	1.75e-165	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
EBNOGNPH_01582	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
EBNOGNPH_01583	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
EBNOGNPH_01584	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBNOGNPH_01585	2.87e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBNOGNPH_01586	2.58e-71	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBNOGNPH_01587	8.78e-55	repA	-	-	S	-	-	-	Replication initiator protein A
EBNOGNPH_01588	1.17e-111	is18	-	-	L	-	-	-	Integrase core domain
EBNOGNPH_01589	1.35e-259	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBNOGNPH_01590	1.44e-59	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
EBNOGNPH_01591	1.11e-68	-	-	-	K	-	-	-	DNA-templated transcription, initiation
EBNOGNPH_01592	3.68e-23	-	-	-	K	-	-	-	DNA-templated transcription, initiation
EBNOGNPH_01594	0.0	-	-	-	V	-	-	-	DNA restriction-modification system
EBNOGNPH_01595	0.0	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
EBNOGNPH_01596	1.02e-59	-	-	-	P	-	-	-	Major Facilitator Superfamily
EBNOGNPH_01597	5.28e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
EBNOGNPH_01598	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
EBNOGNPH_01599	2.08e-265	-	-	-	EGP	-	-	-	Major Facilitator
EBNOGNPH_01600	1.55e-274	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
EBNOGNPH_01601	2.01e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
EBNOGNPH_01602	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
EBNOGNPH_01603	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EBNOGNPH_01604	2.86e-244	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
EBNOGNPH_01605	2.19e-172	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
EBNOGNPH_01606	2.31e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EBNOGNPH_01607	4.35e-108	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EBNOGNPH_01608	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
EBNOGNPH_01609	9.87e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
EBNOGNPH_01610	3.07e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
EBNOGNPH_01611	5.59e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
EBNOGNPH_01612	5.49e-22	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
EBNOGNPH_01613	8.55e-47	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
EBNOGNPH_01614	1.4e-106	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
EBNOGNPH_01615	2.19e-78	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
EBNOGNPH_01616	1.13e-167	-	3.5.2.3, 3.5.2.5	-	F	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EBNOGNPH_01617	3.3e-122	allC	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	Peptidase family M20/M25/M40
EBNOGNPH_01618	1.34e-257	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
EBNOGNPH_01619	5.26e-23	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
EBNOGNPH_01620	1.5e-226	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
EBNOGNPH_01621	3.88e-160	-	-	-	C	-	-	-	nitroreductase
EBNOGNPH_01622	1.98e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
EBNOGNPH_01623	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
EBNOGNPH_01624	8.97e-252	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
EBNOGNPH_01625	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
EBNOGNPH_01626	1.3e-104	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_01628	1.09e-299	-	-	-	G	-	-	-	Polysaccharide deacetylase
EBNOGNPH_01629	2.99e-186	-	-	-	-	-	-	-	-
EBNOGNPH_01630	7.31e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF3892)
EBNOGNPH_01631	1.25e-91	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
EBNOGNPH_01632	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
EBNOGNPH_01633	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
EBNOGNPH_01634	1.14e-179	-	-	-	S	-	-	-	AAA domain
EBNOGNPH_01635	3.05e-55	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
EBNOGNPH_01636	1.06e-27	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Aldo/keto reductase family
EBNOGNPH_01638	3.07e-114	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EBNOGNPH_01639	1.43e-60	-	-	-	T	ko:K14988	ko02020,map02020	ko00000,ko00001,ko00002,ko01001,ko02022	Histidine kinase
EBNOGNPH_01640	1.28e-58	-	-	-	T	-	-	-	regulator
EBNOGNPH_01642	1.21e-125	-	-	-	F	-	-	-	AAA domain
EBNOGNPH_01643	3.81e-108	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01644	1.35e-262	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease)
EBNOGNPH_01645	1.11e-300	-	-	-	L	ko:K07485	-	ko00000	Transposase
EBNOGNPH_01646	4.58e-63	-	-	-	S	-	-	-	AAA ATPase domain
EBNOGNPH_01647	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EBNOGNPH_01648	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
EBNOGNPH_01649	2.57e-226	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
EBNOGNPH_01650	3.7e-194	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
EBNOGNPH_01652	8.85e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
EBNOGNPH_01654	8.19e-76	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EBNOGNPH_01655	7.82e-240	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBNOGNPH_01657	1.04e-245	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
EBNOGNPH_01658	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
EBNOGNPH_01659	2.5e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
EBNOGNPH_01660	2.6e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBNOGNPH_01661	7.7e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
EBNOGNPH_01662	2.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
EBNOGNPH_01663	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
EBNOGNPH_01664	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
EBNOGNPH_01665	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
EBNOGNPH_01666	1.1e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
EBNOGNPH_01667	2.2e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EBNOGNPH_01668	3.66e-72	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
EBNOGNPH_01669	8.05e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
EBNOGNPH_01670	1.62e-312	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EBNOGNPH_01671	2.08e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
EBNOGNPH_01672	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EBNOGNPH_01673	2.75e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EBNOGNPH_01674	5.08e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
EBNOGNPH_01675	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
EBNOGNPH_01676	1.03e-74	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_01677	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EBNOGNPH_01678	2.9e-158	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01679	7.8e-207	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
EBNOGNPH_01680	1.58e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EBNOGNPH_01681	5.52e-241	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
EBNOGNPH_01682	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EBNOGNPH_01683	8.6e-69	-	-	-	-	-	-	-	-
EBNOGNPH_01684	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EBNOGNPH_01685	8.27e-111	-	-	-	L	-	-	-	nuclease
EBNOGNPH_01686	1.46e-207	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
EBNOGNPH_01687	2.93e-58	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_01688	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
EBNOGNPH_01689	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EBNOGNPH_01690	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
EBNOGNPH_01691	2.93e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EBNOGNPH_01692	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EBNOGNPH_01693	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EBNOGNPH_01694	2e-206	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBNOGNPH_01695	9.82e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBNOGNPH_01696	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
EBNOGNPH_01697	3.44e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
EBNOGNPH_01698	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
EBNOGNPH_01699	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
EBNOGNPH_01700	1.09e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
EBNOGNPH_01701	2.61e-148	-	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_01703	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
EBNOGNPH_01704	5.32e-229	-	-	-	-	-	-	-	-
EBNOGNPH_01705	8.07e-203	-	-	-	-	-	-	-	-
EBNOGNPH_01706	4.76e-19	-	-	-	-	-	-	-	-
EBNOGNPH_01707	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
EBNOGNPH_01708	2.56e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBNOGNPH_01709	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
EBNOGNPH_01710	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
EBNOGNPH_01711	2.13e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
EBNOGNPH_01712	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
EBNOGNPH_01713	1.68e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
EBNOGNPH_01714	3.66e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EBNOGNPH_01715	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EBNOGNPH_01716	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EBNOGNPH_01717	0.0	-	-	-	S	-	-	-	membrane
EBNOGNPH_01718	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EBNOGNPH_01719	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
EBNOGNPH_01720	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EBNOGNPH_01721	4.45e-253	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBNOGNPH_01722	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EBNOGNPH_01723	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EBNOGNPH_01724	6.16e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBNOGNPH_01725	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
EBNOGNPH_01726	4.58e-196	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EBNOGNPH_01727	4.54e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
EBNOGNPH_01728	1.88e-298	-	-	-	V	-	-	-	MatE
EBNOGNPH_01729	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EBNOGNPH_01730	1.38e-155	csrR	-	-	K	-	-	-	response regulator
EBNOGNPH_01731	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
EBNOGNPH_01732	2.79e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
EBNOGNPH_01733	2.38e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
EBNOGNPH_01734	7.76e-182	yqeM	-	-	Q	-	-	-	Methyltransferase
EBNOGNPH_01735	2.79e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EBNOGNPH_01736	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
EBNOGNPH_01737	1.62e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBNOGNPH_01738	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
EBNOGNPH_01739	2.29e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
EBNOGNPH_01740	2.8e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
EBNOGNPH_01741	5.46e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
EBNOGNPH_01742	2.21e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
EBNOGNPH_01743	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBNOGNPH_01744	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
EBNOGNPH_01745	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBNOGNPH_01746	2.66e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
EBNOGNPH_01747	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
EBNOGNPH_01748	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBNOGNPH_01749	4.15e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EBNOGNPH_01750	6.22e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EBNOGNPH_01751	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBNOGNPH_01752	3.28e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
EBNOGNPH_01754	4.29e-220	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
EBNOGNPH_01759	3.61e-46	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
EBNOGNPH_01760	3.44e-33	-	-	-	-	-	-	-	-
EBNOGNPH_01763	1.18e-148	-	-	-	K	-	-	-	Phage regulatory protein
EBNOGNPH_01764	1.24e-39	-	-	-	S	-	-	-	sequence-specific DNA binding
EBNOGNPH_01765	2.7e-22	-	-	-	KT	-	-	-	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EBNOGNPH_01767	9.44e-139	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
EBNOGNPH_01768	3.51e-83	-	-	-	-	-	-	-	-
EBNOGNPH_01769	4.46e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF4231)
EBNOGNPH_01770	8.68e-87	-	-	-	S	-	-	-	MTH538 TIR-like domain (DUF1863)
EBNOGNPH_01771	2.5e-38	-	-	-	-	-	-	-	-
EBNOGNPH_01772	1.38e-55	-	-	-	NU	-	-	-	Domain of unknown function (DUF5067)
EBNOGNPH_01776	3.18e-201	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_01777	3.02e-61	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_01779	2.64e-119	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
EBNOGNPH_01780	7.15e-157	vanR	-	-	K	-	-	-	response regulator
EBNOGNPH_01781	8.86e-267	hpk31	-	-	T	-	-	-	Histidine kinase
EBNOGNPH_01782	3.95e-268	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EBNOGNPH_01783	2.17e-187	-	-	-	E	-	-	-	AzlC protein
EBNOGNPH_01784	2.22e-78	-	-	-	S	-	-	-	branched-chain amino acid
EBNOGNPH_01785	1.09e-129	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
EBNOGNPH_01786	2.46e-292	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
EBNOGNPH_01787	8.01e-85	XK27_08315	-	-	M	-	-	-	Sulfatase
EBNOGNPH_01788	6.31e-232	XK27_08315	-	-	M	-	-	-	Sulfatase
EBNOGNPH_01789	5.86e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
EBNOGNPH_01790	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
EBNOGNPH_01792	5.86e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
EBNOGNPH_01793	1.73e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
EBNOGNPH_01794	1.15e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
EBNOGNPH_01795	9.23e-270	cps3F	-	-	-	-	-	-	-
EBNOGNPH_01796	1.4e-30	-	-	-	M	-	-	-	biosynthesis protein
EBNOGNPH_01797	5.58e-170	-	-	-	S	-	-	-	Membrane
EBNOGNPH_01798	3.66e-191	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EBNOGNPH_01799	3.1e-16	-	-	-	S	-	-	-	YjcQ protein
EBNOGNPH_01801	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBNOGNPH_01802	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EBNOGNPH_01803	1.43e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
EBNOGNPH_01804	2.03e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBNOGNPH_01805	6.63e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
EBNOGNPH_01806	3.8e-315	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
EBNOGNPH_01807	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
EBNOGNPH_01808	1.37e-248	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
EBNOGNPH_01809	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
EBNOGNPH_01810	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBNOGNPH_01812	2.83e-81	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_01813	0.0	-	-	-	EGP	-	-	-	Major Facilitator
EBNOGNPH_01814	9.29e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EBNOGNPH_01815	2.2e-66	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EBNOGNPH_01816	3.22e-85	-	-	-	-	-	-	-	-
EBNOGNPH_01817	1.58e-70	-	-	-	-	-	-	-	-
EBNOGNPH_01818	6.92e-280	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
EBNOGNPH_01819	1.08e-298	yagE	-	-	E	-	-	-	Amino acid permease
EBNOGNPH_01820	3.11e-100	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
EBNOGNPH_01821	5.27e-237	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
EBNOGNPH_01822	3.27e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
EBNOGNPH_01823	1.33e-166	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EBNOGNPH_01824	1.3e-301	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EBNOGNPH_01825	2.36e-168	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
EBNOGNPH_01826	1.24e-305	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
EBNOGNPH_01827	1.24e-160	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
EBNOGNPH_01828	1.68e-65	-	-	-	-	-	-	-	-
EBNOGNPH_01829	4.67e-191	-	-	-	E	-	-	-	Major Facilitator Superfamily
EBNOGNPH_01830	9.01e-53	-	-	-	E	-	-	-	Major Facilitator Superfamily
EBNOGNPH_01831	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
EBNOGNPH_01832	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EBNOGNPH_01833	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
EBNOGNPH_01834	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EBNOGNPH_01835	6.56e-165	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EBNOGNPH_01836	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
EBNOGNPH_01838	1.48e-29	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EBNOGNPH_01840	4.12e-67	-	-	-	L	-	-	-	Type II restriction endonuclease, Alw26I Eco31I Esp3I family
EBNOGNPH_01841	9.34e-98	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
EBNOGNPH_01842	5.52e-65	-	-	-	K	-	-	-	TRANSCRIPTIONal
EBNOGNPH_01845	4.53e-50	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_01846	1.11e-260	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
EBNOGNPH_01847	3.41e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
EBNOGNPH_01848	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EBNOGNPH_01849	7e-243	-	-	-	M	-	-	-	Glycosyltransferase like family 2
EBNOGNPH_01850	5.45e-257	cps3I	-	-	G	-	-	-	Acyltransferase family
EBNOGNPH_01867	1.02e-174	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EBNOGNPH_01872	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EBNOGNPH_01873	7.24e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EBNOGNPH_01874	1.69e-262	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
EBNOGNPH_01875	1.46e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
EBNOGNPH_01876	1.5e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
EBNOGNPH_01877	9.49e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBNOGNPH_01878	8.94e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EBNOGNPH_01879	2.67e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
EBNOGNPH_01880	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
EBNOGNPH_01881	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EBNOGNPH_01882	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
EBNOGNPH_01883	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
EBNOGNPH_01884	6.91e-76	-	-	-	-	-	-	-	-
EBNOGNPH_01885	7.65e-104	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
EBNOGNPH_01886	5.37e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EBNOGNPH_01887	3.03e-30	ftsL	-	-	D	-	-	-	Cell division protein FtsL
EBNOGNPH_01888	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EBNOGNPH_01889	4.46e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBNOGNPH_01890	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EBNOGNPH_01891	2.06e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EBNOGNPH_01892	5.43e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EBNOGNPH_01893	4.88e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EBNOGNPH_01894	1.23e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EBNOGNPH_01895	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EBNOGNPH_01896	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
EBNOGNPH_01897	5.03e-186	ylmH	-	-	S	-	-	-	S4 domain protein
EBNOGNPH_01898	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
EBNOGNPH_01900	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EBNOGNPH_01901	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
EBNOGNPH_01902	5.21e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
EBNOGNPH_01904	3.26e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EBNOGNPH_01905	7.86e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
EBNOGNPH_01906	9.82e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EBNOGNPH_01907	0.0	-	-	-	S	-	-	-	amidohydrolase
EBNOGNPH_01908	1.08e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EBNOGNPH_01909	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
EBNOGNPH_01910	9.37e-159	-	-	-	S	-	-	-	repeat protein
EBNOGNPH_01911	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EBNOGNPH_01912	3.81e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBNOGNPH_01913	2.39e-98	-	-	-	P	-	-	-	ArsC family
EBNOGNPH_01914	8.46e-239	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
EBNOGNPH_01915	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
EBNOGNPH_01916	6.12e-98	-	-	-	-	-	-	-	-
EBNOGNPH_01917	1.22e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EBNOGNPH_01918	1.55e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
EBNOGNPH_01919	9.34e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
EBNOGNPH_01920	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
EBNOGNPH_01921	1.02e-277	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
EBNOGNPH_01922	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
EBNOGNPH_01923	3.65e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
EBNOGNPH_01924	2.51e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBNOGNPH_01925	1.96e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
EBNOGNPH_01926	1.92e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_01930	2.14e-107	-	-	-	C	-	-	-	Aldo keto reductase
EBNOGNPH_01931	9.2e-100	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
EBNOGNPH_01933	4.36e-34	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
EBNOGNPH_01934	8.61e-72	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
EBNOGNPH_01935	1.84e-155	pnb	-	-	C	-	-	-	nitroreductase
EBNOGNPH_01936	6.59e-17	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
EBNOGNPH_01937	2.69e-57	yodA	-	-	S	-	-	-	Tautomerase enzyme
EBNOGNPH_01938	1.97e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
EBNOGNPH_01941	9.36e-124	-	-	-	K	-	-	-	transcriptional regulator
EBNOGNPH_01942	3.53e-172	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EBNOGNPH_01945	8.11e-52	-	-	-	S	-	-	-	Cytochrome B5
EBNOGNPH_01946	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EBNOGNPH_01947	4.27e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
EBNOGNPH_01948	3.39e-83	-	-	-	-	-	-	-	-
EBNOGNPH_01949	0.0	-	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
EBNOGNPH_01950	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
EBNOGNPH_01951	1.19e-61	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EBNOGNPH_01952	9.02e-146	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
EBNOGNPH_01953	1.38e-114	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_01954	7.33e-151	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
EBNOGNPH_01955	3.94e-121	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
EBNOGNPH_01956	2.77e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
EBNOGNPH_01957	7.48e-298	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
EBNOGNPH_01958	3.09e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
EBNOGNPH_01959	8.5e-249	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_01960	4e-54	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_01961	2.97e-164	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_01962	1.7e-281	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_01963	4.86e-199	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EBNOGNPH_01964	5.01e-188	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
EBNOGNPH_01965	1.54e-170	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
EBNOGNPH_01966	2.5e-146	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_01967	7.39e-61	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
EBNOGNPH_01968	1.84e-44	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
EBNOGNPH_01969	1.11e-98	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
EBNOGNPH_01970	3.13e-73	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
EBNOGNPH_01971	2.4e-71	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_01972	1.47e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
EBNOGNPH_01973	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
EBNOGNPH_01974	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
EBNOGNPH_01975	6.65e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
EBNOGNPH_01976	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
EBNOGNPH_01977	9e-29	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_01978	5.92e-157	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EBNOGNPH_01980	1.38e-114	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_01981	5.59e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
EBNOGNPH_01982	5.56e-60	-	-	-	M	-	-	-	Acetyltransferase (Isoleucine patch superfamily)
EBNOGNPH_01983	8.12e-159	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_01984	1.96e-107	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_01985	1.79e-97	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
EBNOGNPH_01986	5.89e-171	XK27_07210	-	-	S	-	-	-	B3 4 domain
EBNOGNPH_01987	1.49e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
EBNOGNPH_01989	9.35e-55	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
EBNOGNPH_01990	2.91e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EBNOGNPH_01991	9.43e-56	-	-	-	IQ	-	-	-	reductase
EBNOGNPH_01992	5.16e-15	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBNOGNPH_01993	1.29e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EBNOGNPH_01994	5.28e-66	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_01995	7.29e-116	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_01996	5.94e-100	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
EBNOGNPH_01997	8.83e-160	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EBNOGNPH_01998	3.78e-71	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
EBNOGNPH_01999	9.03e-81	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
EBNOGNPH_02000	7.76e-164	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
EBNOGNPH_02001	3.65e-50	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
EBNOGNPH_02002	4.82e-189	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
EBNOGNPH_02003	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
EBNOGNPH_02004	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EBNOGNPH_02005	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
EBNOGNPH_02006	2.22e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
EBNOGNPH_02007	1.52e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBNOGNPH_02008	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
EBNOGNPH_02009	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
EBNOGNPH_02010	1.13e-157	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
EBNOGNPH_02011	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EBNOGNPH_02012	4.99e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
EBNOGNPH_02013	1.6e-194	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
EBNOGNPH_02014	3.3e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
EBNOGNPH_02015	3.56e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
EBNOGNPH_02016	3.19e-39	-	-	-	-	-	-	-	-
EBNOGNPH_02017	5.25e-38	-	-	-	-	-	-	-	-
EBNOGNPH_02019	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBNOGNPH_02020	4.94e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EBNOGNPH_02021	1.54e-279	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EBNOGNPH_02022	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
EBNOGNPH_02023	1.98e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EBNOGNPH_02024	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBNOGNPH_02025	2.2e-215	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EBNOGNPH_02026	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBNOGNPH_02027	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
EBNOGNPH_02028	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EBNOGNPH_02029	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
EBNOGNPH_02030	4.7e-163	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
EBNOGNPH_02031	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
EBNOGNPH_02032	3.08e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EBNOGNPH_02033	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
EBNOGNPH_02034	1.68e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
EBNOGNPH_02035	5.57e-316	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBNOGNPH_02036	5.61e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBNOGNPH_02037	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBNOGNPH_02038	5.94e-282	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBNOGNPH_02039	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EBNOGNPH_02040	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
EBNOGNPH_02042	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
EBNOGNPH_02043	7.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
EBNOGNPH_02046	1.1e-50	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_02047	4.73e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBNOGNPH_02048	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBNOGNPH_02049	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
EBNOGNPH_02050	8.37e-58	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_02051	7.25e-10	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_02052	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
EBNOGNPH_02053	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
EBNOGNPH_02054	5.57e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EBNOGNPH_02055	9.14e-155	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EBNOGNPH_02056	1.26e-63	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EBNOGNPH_02057	1.57e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
EBNOGNPH_02058	9.28e-277	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
EBNOGNPH_02059	9.13e-132	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EBNOGNPH_02060	6.13e-298	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
EBNOGNPH_02061	1.68e-225	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
EBNOGNPH_02062	1.1e-93	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBNOGNPH_02063	1.25e-109	-	-	-	P	-	-	-	Cation efflux family
EBNOGNPH_02064	4.68e-66	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
EBNOGNPH_02065	2.25e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
EBNOGNPH_02066	2.84e-145	-	-	-	S	-	-	-	EcsC protein family
EBNOGNPH_02067	5.74e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EBNOGNPH_02068	1.08e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
EBNOGNPH_02069	8.73e-41	-	-	-	K	-	-	-	LytTr DNA-binding domain
EBNOGNPH_02070	1.08e-179	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
EBNOGNPH_02071	1.46e-123	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EBNOGNPH_02072	2.07e-32	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
EBNOGNPH_02075	8.89e-136	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
EBNOGNPH_02076	8.35e-280	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
EBNOGNPH_02077	2.33e-10	-	-	-	-	-	-	-	-
EBNOGNPH_02079	1.55e-74	-	-	-	-	-	-	-	-
EBNOGNPH_02081	1.4e-168	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
EBNOGNPH_02082	4.49e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EBNOGNPH_02083	9.18e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
EBNOGNPH_02084	1.27e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
EBNOGNPH_02085	1.43e-110	-	-	-	K	-	-	-	GNAT family
EBNOGNPH_02087	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
EBNOGNPH_02088	2.82e-234	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
EBNOGNPH_02089	4.03e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
EBNOGNPH_02090	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBNOGNPH_02091	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EBNOGNPH_02092	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
EBNOGNPH_02093	1.42e-215	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
EBNOGNPH_02094	9.65e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
EBNOGNPH_02095	2.15e-299	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
EBNOGNPH_02096	5.85e-192	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
EBNOGNPH_02097	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
EBNOGNPH_02098	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EBNOGNPH_02099	1.3e-110	-	-	-	-	-	-	-	-
EBNOGNPH_02100	7.69e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
EBNOGNPH_02101	3.27e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
EBNOGNPH_02102	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
EBNOGNPH_02103	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
EBNOGNPH_02104	1.51e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
EBNOGNPH_02105	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
EBNOGNPH_02106	4.09e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
EBNOGNPH_02107	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EBNOGNPH_02108	1.06e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EBNOGNPH_02109	1.78e-22	-	-	-	-	-	-	-	-
EBNOGNPH_02110	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EBNOGNPH_02111	8.24e-248	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
EBNOGNPH_02112	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
EBNOGNPH_02113	5.3e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
EBNOGNPH_02114	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
EBNOGNPH_02115	1.92e-203	-	-	-	-	-	-	-	-
EBNOGNPH_02116	1.25e-09	-	-	-	-	-	-	-	-
EBNOGNPH_02117	6.25e-78	-	-	-	-	-	-	-	-
EBNOGNPH_02118	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
EBNOGNPH_02120	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
EBNOGNPH_02121	2.72e-314	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
EBNOGNPH_02122	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBNOGNPH_02123	6.86e-175	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
EBNOGNPH_02124	2.22e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EBNOGNPH_02125	1.69e-155	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBNOGNPH_02126	1.48e-74	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EBNOGNPH_02127	1.47e-99	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
EBNOGNPH_02128	3.97e-77	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
EBNOGNPH_02129	1.02e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
EBNOGNPH_02130	6.02e-107	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
EBNOGNPH_02131	1.11e-269	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EBNOGNPH_02132	5.57e-103	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EBNOGNPH_02133	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
EBNOGNPH_02134	1.49e-189	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
EBNOGNPH_02135	8.59e-142	-	-	-	L	-	-	-	AlwI restriction endonuclease
EBNOGNPH_02137	1.7e-64	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EBNOGNPH_02138	4.24e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
EBNOGNPH_02139	2.43e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
EBNOGNPH_02141	7.61e-45	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
EBNOGNPH_02142	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
EBNOGNPH_02143	1.32e-83	-	-	-	L	-	-	-	MULE transposase domain
EBNOGNPH_02144	7.66e-84	-	-	-	S	-	-	-	Fic/DOC family
EBNOGNPH_02147	1.51e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
EBNOGNPH_02148	8.8e-71	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
EBNOGNPH_02149	4.74e-23	-	-	-	-	-	-	-	-
EBNOGNPH_02150	1.19e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
EBNOGNPH_02151	3.37e-96	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EBNOGNPH_02152	9.52e-115	-	-	-	-	-	-	-	-
EBNOGNPH_02153	7.13e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
EBNOGNPH_02154	8.34e-101	-	-	-	-	-	-	-	-