ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KMDGHHAD_00001 8.4e-51 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
KMDGHHAD_00002 1.58e-11 yaaL - - S - - - Protein of unknown function (DUF2508)
KMDGHHAD_00003 4.93e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KMDGHHAD_00004 1.28e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KMDGHHAD_00005 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMDGHHAD_00006 1.78e-113 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KMDGHHAD_00007 3.79e-153 cls2 - - I - - - PLD-like domain
KMDGHHAD_00008 2.88e-10 - - - - - - - -
KMDGHHAD_00009 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KMDGHHAD_00011 4.03e-87 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KMDGHHAD_00012 1.93e-20 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KMDGHHAD_00013 4.84e-161 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KMDGHHAD_00014 4.39e-206 dtpT - - E ko:K03305 - ko00000 POT family
KMDGHHAD_00015 1.74e-65 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
KMDGHHAD_00016 1.07e-39 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KMDGHHAD_00017 1.76e-182 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
KMDGHHAD_00018 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KMDGHHAD_00019 1.98e-105 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KMDGHHAD_00021 1.84e-40 - - - S - - - transposase or invertase
KMDGHHAD_00023 1.5e-168 yodH - - Q - - - Methyltransferase
KMDGHHAD_00024 1.57e-186 yjaZ - - O - - - Zn-dependent protease
KMDGHHAD_00025 7.07e-44 yodI - - - - - - -
KMDGHHAD_00026 1.82e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMDGHHAD_00028 8.96e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KMDGHHAD_00029 3.09e-59 - - - S - - - DsrE/DsrF-like family
KMDGHHAD_00030 7.5e-100 - - - - - - - -
KMDGHHAD_00031 8.41e-235 - 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMDGHHAD_00032 1.66e-269 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
KMDGHHAD_00033 2.82e-111 - - - - - - - -
KMDGHHAD_00034 1.08e-101 - - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMDGHHAD_00035 8.39e-180 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KMDGHHAD_00036 1.01e-195 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KMDGHHAD_00037 3.91e-31 sspK - - S ko:K06428 - ko00000 reproduction
KMDGHHAD_00038 4.2e-240 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
KMDGHHAD_00039 5.62e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
KMDGHHAD_00040 2.92e-108 - - - - - - - -
KMDGHHAD_00041 5.2e-184 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KMDGHHAD_00042 2.87e-39 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
KMDGHHAD_00043 3.9e-27 - - - S - - - Stage 0 Sporulation Regulatory protein
KMDGHHAD_00045 7.38e-307 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_00046 1.36e-76 - - - K - - - MarR family
KMDGHHAD_00047 1.35e-64 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMDGHHAD_00048 2.79e-113 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMDGHHAD_00049 1.4e-83 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KMDGHHAD_00050 1.28e-82 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMDGHHAD_00051 1.13e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMDGHHAD_00052 5.61e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KMDGHHAD_00053 7.85e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KMDGHHAD_00054 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KMDGHHAD_00055 1.94e-124 spmA - - S ko:K06373 - ko00000 Spore maturation protein
KMDGHHAD_00056 1.14e-113 spmB - - S ko:K06374 - ko00000 Spore maturation protein
KMDGHHAD_00057 3.11e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KMDGHHAD_00058 2.14e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KMDGHHAD_00059 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
KMDGHHAD_00060 2.11e-292 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KMDGHHAD_00061 2.06e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMDGHHAD_00062 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_00063 1.57e-175 - - - M - - - COG0739 Membrane proteins related to metalloendopeptidases
KMDGHHAD_00064 1.58e-125 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KMDGHHAD_00065 1.69e-54 fer - - C ko:K05337 - ko00000 Ferredoxin
KMDGHHAD_00066 2.71e-259 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
KMDGHHAD_00067 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMDGHHAD_00068 6e-130 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
KMDGHHAD_00070 1.26e-105 ypbF - - S - - - Protein of unknown function (DUF2663)
KMDGHHAD_00071 2.19e-135 cotJC - - P ko:K06334 - ko00000 Spore Coat
KMDGHHAD_00072 1.24e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
KMDGHHAD_00073 8.41e-54 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
KMDGHHAD_00074 5.66e-184 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KMDGHHAD_00075 3.16e-129 - - - NOT ko:K16511 - ko00000 Negative regulator of genetic competence (MecA)
KMDGHHAD_00076 6.55e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KMDGHHAD_00077 1.77e-237 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
KMDGHHAD_00078 9.82e-164 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
KMDGHHAD_00079 4.17e-193 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
KMDGHHAD_00080 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
KMDGHHAD_00081 1.84e-153 ypfA - - M - - - Flagellar protein YcgR
KMDGHHAD_00082 2.98e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KMDGHHAD_00083 2.71e-260 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KMDGHHAD_00084 9.95e-21 - - - S - - - YpzI-like protein
KMDGHHAD_00085 2.35e-13 yphA - - - - - - -
KMDGHHAD_00086 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KMDGHHAD_00087 2.27e-245 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KMDGHHAD_00088 7.83e-13 yphE - - S - - - Protein of unknown function (DUF2768)
KMDGHHAD_00089 1.7e-175 yphF - - - - - - -
KMDGHHAD_00090 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMDGHHAD_00091 1.54e-56 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KMDGHHAD_00092 1.85e-44 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KMDGHHAD_00093 1.05e-184 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KMDGHHAD_00094 2.4e-168 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KMDGHHAD_00095 5.62e-226 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KMDGHHAD_00096 8.2e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KMDGHHAD_00097 4.49e-187 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
KMDGHHAD_00098 1.7e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KMDGHHAD_00099 1.46e-264 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KMDGHHAD_00100 6.31e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KMDGHHAD_00101 1.79e-267 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KMDGHHAD_00102 3.72e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KMDGHHAD_00103 4.07e-305 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KMDGHHAD_00104 2.54e-305 ypiA - - S - - - COG0457 FOG TPR repeat
KMDGHHAD_00105 3.68e-130 ypiB - - S - - - Belongs to the UPF0302 family
KMDGHHAD_00106 1.46e-111 ypiF - - S - - - Protein of unknown function (DUF2487)
KMDGHHAD_00107 5.32e-129 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
KMDGHHAD_00108 2.94e-164 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
KMDGHHAD_00109 1.52e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
KMDGHHAD_00110 2.97e-142 ypjA - - S - - - membrane
KMDGHHAD_00111 5.43e-184 ypjB - - S - - - sporulation protein
KMDGHHAD_00112 3.83e-137 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
KMDGHHAD_00113 1.88e-106 queT - - S - - - QueT transporter
KMDGHHAD_00114 1.65e-206 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMDGHHAD_00115 3.2e-76 ypjD - - S - - - Nucleotide pyrophosphohydrolase
KMDGHHAD_00116 1.15e-191 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KMDGHHAD_00117 3.29e-171 ypjG - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
KMDGHHAD_00118 9.14e-283 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
KMDGHHAD_00119 4.76e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KMDGHHAD_00120 6.35e-230 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KMDGHHAD_00121 8.05e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KMDGHHAD_00122 4.34e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KMDGHHAD_00123 8.4e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KMDGHHAD_00124 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KMDGHHAD_00125 6.71e-102 ypmB - - S - - - protein conserved in bacteria
KMDGHHAD_00126 7.45e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KMDGHHAD_00127 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
KMDGHHAD_00128 0.0 - - - O - - - AAA domain
KMDGHHAD_00129 4.05e-103 - - - E - - - COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_00130 5.74e-304 - - - S - - - protein conserved in bacteria
KMDGHHAD_00131 7.1e-06 - - - - - - - -
KMDGHHAD_00132 1.66e-144 ppiA 5.2.1.8 - O ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMDGHHAD_00133 3.04e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
KMDGHHAD_00134 3e-23 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
KMDGHHAD_00135 0.0 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KMDGHHAD_00136 1.1e-133 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMDGHHAD_00137 1.31e-149 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KMDGHHAD_00138 3.54e-210 - - - S - - - Protein of unknown function (DUF1646)
KMDGHHAD_00139 1.24e-118 yjjX - - F - - - Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KMDGHHAD_00140 2.61e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KMDGHHAD_00141 2.11e-69 ytzB - - S - - - small secreted protein
KMDGHHAD_00142 8.75e-174 cysK5 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KMDGHHAD_00143 1.05e-36 - - - - - - - -
KMDGHHAD_00146 1.22e-30 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KMDGHHAD_00147 1.59e-173 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
KMDGHHAD_00148 4.27e-186 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KMDGHHAD_00149 4.65e-56 - - - - - - - -
KMDGHHAD_00150 0.0 - - - H - - - HemY protein
KMDGHHAD_00152 6.71e-109 - - - S ko:K02351 - ko00000 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
KMDGHHAD_00153 1.37e-78 - - - S - - - Predicted membrane protein (DUF2243)
KMDGHHAD_00154 8.33e-64 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KMDGHHAD_00156 4.23e-115 - - - E - - - Zn peptidase
KMDGHHAD_00157 3.27e-10 - - - K - - - Cro/C1-type HTH DNA-binding domain
KMDGHHAD_00158 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KMDGHHAD_00159 6.7e-72 yrzD - - S - - - Post-transcriptional regulator
KMDGHHAD_00160 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMDGHHAD_00161 4.76e-137 yrbG - - S - - - membrane
KMDGHHAD_00162 2.67e-83 yrzE - - S - - - Protein of unknown function (DUF3792)
KMDGHHAD_00163 7.67e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
KMDGHHAD_00164 4.88e-284 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KMDGHHAD_00165 1.42e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KMDGHHAD_00166 4.52e-37 yrzS - - S - - - Protein of unknown function (DUF2905)
KMDGHHAD_00167 4.16e-234 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KMDGHHAD_00168 2.52e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KMDGHHAD_00169 1.09e-162 yebC - - K - - - transcriptional regulatory protein
KMDGHHAD_00170 3.2e-242 - - - M - - - choline kinase involved in LPS biosynthesis
KMDGHHAD_00171 2.03e-227 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
KMDGHHAD_00172 7.65e-125 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KMDGHHAD_00173 9.91e-205 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KMDGHHAD_00174 6.2e-98 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
KMDGHHAD_00175 1.83e-314 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMDGHHAD_00176 3.43e-128 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
KMDGHHAD_00177 5.39e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KMDGHHAD_00178 6.88e-71 ysxB - - J ko:K07584 - ko00000 ribosomal protein
KMDGHHAD_00179 2.58e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KMDGHHAD_00180 0.0 rng - - J ko:K08301 - ko00000,ko01000,ko03009,ko03019 ribonuclease, Rne Rng family
KMDGHHAD_00181 9.19e-209 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
KMDGHHAD_00182 1.97e-175 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KMDGHHAD_00183 9e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KMDGHHAD_00184 1.38e-156 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KMDGHHAD_00185 2.23e-113 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
KMDGHHAD_00186 9.97e-188 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KMDGHHAD_00187 1.34e-233 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
KMDGHHAD_00188 4.65e-158 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KMDGHHAD_00189 7.3e-221 spoIIB - - - ko:K06380 - ko00000 -
KMDGHHAD_00190 1.24e-184 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KMDGHHAD_00191 1.84e-147 - - - - ko:K02664 - ko00000,ko02035,ko02044 -
KMDGHHAD_00192 1.65e-118 - - - NU ko:K02663 - ko00000,ko02035,ko02044 PFAM Fimbrial assembly family protein
KMDGHHAD_00193 4.07e-246 - - - NU ko:K02662,ko:K02663 - ko00000,ko02035,ko02044 COG4972 Tfp pilus assembly protein, ATPase PilM
KMDGHHAD_00194 6.08e-82 - - - NU ko:K02650 ko02020,map02020 ko00000,ko00001,ko02035,ko02044 Prokaryotic N-terminal methylation motif
KMDGHHAD_00195 9.56e-268 pilC - - NU ko:K02653 - ko00000,ko02035,ko02044 type II secretion system
KMDGHHAD_00196 2.77e-248 pilT - - NU ko:K02669 - ko00000,ko02035,ko02044 twitching motility protein
KMDGHHAD_00197 0.0 pilB - - NU ko:K02243,ko:K02652 - ko00000,ko00002,ko02035,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KMDGHHAD_00198 9.5e-294 - - - V - - - G5
KMDGHHAD_00199 1.67e-163 - - - S - - - PRC-barrel domain
KMDGHHAD_00200 1.17e-294 - - - - - - - -
KMDGHHAD_00201 0.0 - - - NU - - - Pilus assembly protein PilX
KMDGHHAD_00202 1.2e-111 - - - - - - - -
KMDGHHAD_00203 9.73e-06 - - - NU - - - Prokaryotic N-terminal methylation motif
KMDGHHAD_00204 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KMDGHHAD_00205 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KMDGHHAD_00206 3.74e-36 - - - - - - - -
KMDGHHAD_00207 1.21e-287 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMDGHHAD_00208 4.72e-304 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
KMDGHHAD_00209 9.69e-317 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KMDGHHAD_00210 6.18e-237 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
KMDGHHAD_00211 9.06e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KMDGHHAD_00212 1.26e-217 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KMDGHHAD_00213 8.69e-191 hemX - - O ko:K02497 - ko00000 cytochrome C
KMDGHHAD_00214 1.09e-308 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KMDGHHAD_00215 3.11e-116 ysxD - - - - - - -
KMDGHHAD_00216 8.22e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KMDGHHAD_00217 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KMDGHHAD_00218 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
KMDGHHAD_00219 1.2e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KMDGHHAD_00220 8.15e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KMDGHHAD_00221 1.51e-235 - - - S - - - chaperone-mediated protein folding
KMDGHHAD_00222 3.75e-306 - - - P - - - Voltage gated chloride channel
KMDGHHAD_00223 2.41e-87 - - - - - - - -
KMDGHHAD_00224 6.87e-205 tnp - - L ko:K07493 - ko00000 transposase activity
KMDGHHAD_00225 3.63e-95 - - - S - - - Protein of unknown function (DUF2961)
KMDGHHAD_00226 0.0 - - - - - - - -
KMDGHHAD_00227 1.55e-274 - - - G - - - Major facilitator Superfamily
KMDGHHAD_00228 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMDGHHAD_00229 1.78e-300 mvaA 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Hydroxymethylglutaryl-coenzyme A reductase
KMDGHHAD_00230 1.64e-206 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMDGHHAD_00231 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMDGHHAD_00232 3.34e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KMDGHHAD_00233 5.07e-165 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
KMDGHHAD_00234 4.56e-136 thiT - - S ko:K16789 - ko00000,ko02000 Proton-coupled thiamine transporter YuaJ
KMDGHHAD_00235 8.2e-210 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMDGHHAD_00236 2.51e-103 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
KMDGHHAD_00237 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
KMDGHHAD_00238 4.89e-144 yocH - - M - - - COG1388 FOG LysM repeat
KMDGHHAD_00239 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMDGHHAD_00240 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_00241 1.99e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
KMDGHHAD_00242 3.4e-229 yqxL - - P - - - Mg2 transporter protein
KMDGHHAD_00243 2.7e-91 - - - S - - - CHY zinc finger
KMDGHHAD_00244 9.33e-275 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KMDGHHAD_00245 6.68e-143 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KMDGHHAD_00246 7.21e-299 hisD 1.1.1.23, 1.1.1.308 - E ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KMDGHHAD_00247 6.73e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KMDGHHAD_00248 9.55e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KMDGHHAD_00249 3.67e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KMDGHHAD_00250 7.72e-179 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KMDGHHAD_00251 1.15e-155 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
KMDGHHAD_00252 2.08e-54 - - - O - - - Belongs to the sulfur carrier protein TusA family
KMDGHHAD_00253 5.13e-309 - - - S ko:K07112 - ko00000 Sulphur transport
KMDGHHAD_00254 1.01e-222 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
KMDGHHAD_00255 2.24e-284 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
KMDGHHAD_00256 1.62e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KMDGHHAD_00257 1.62e-174 ykrK - - S - - - Domain of unknown function (DUF1836)
KMDGHHAD_00258 1.48e-47 - - - - - - - -
KMDGHHAD_00259 6.02e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
KMDGHHAD_00260 1.18e-275 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
KMDGHHAD_00261 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
KMDGHHAD_00262 1.07e-44 - - - S - - - ATP synthase, subunit b
KMDGHHAD_00263 7.2e-130 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMDGHHAD_00265 1.15e-43 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock
KMDGHHAD_00266 1.7e-154 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KMDGHHAD_00267 2.78e-222 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
KMDGHHAD_00268 1.05e-59 - - - S - - - Protein of unknown function (DUF1292)
KMDGHHAD_00269 1.41e-63 yxiS - - - - - - -
KMDGHHAD_00270 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
KMDGHHAD_00271 1.19e-177 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_00272 2.51e-236 bceS 2.7.13.3 - T ko:K11629 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KMDGHHAD_00273 1.39e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMDGHHAD_00274 1.84e-125 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacitracin ABC transporter ATP-binding protein
KMDGHHAD_00275 1.07e-34 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacitracin ABC transporter ATP-binding protein
KMDGHHAD_00276 8.05e-42 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMDGHHAD_00277 9.65e-53 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMDGHHAD_00278 2.33e-68 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KMDGHHAD_00279 9.84e-172 - - - L - - - PFAM Transposase, Mutator
KMDGHHAD_00280 0.0 - - - L - - - Transposase
KMDGHHAD_00281 7.18e-76 - - - - - - - -
KMDGHHAD_00282 2.36e-42 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
KMDGHHAD_00283 9.02e-177 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMDGHHAD_00286 8.65e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KMDGHHAD_00287 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMDGHHAD_00288 9.21e-216 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMDGHHAD_00289 3.12e-61 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KMDGHHAD_00290 1.05e-114 yshB - - S - - - membrane protein, required for colicin V production
KMDGHHAD_00291 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
KMDGHHAD_00292 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KMDGHHAD_00293 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_00294 5.75e-135 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_00295 3.14e-180 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
KMDGHHAD_00296 1.13e-173 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
KMDGHHAD_00297 4.08e-222 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
KMDGHHAD_00298 2.89e-311 ybbC - - S - - - protein conserved in bacteria
KMDGHHAD_00299 1.16e-285 mvaS 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KMDGHHAD_00300 3.38e-13 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
KMDGHHAD_00301 6.87e-135 - - - - - - - -
KMDGHHAD_00302 3.05e-218 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMDGHHAD_00303 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
KMDGHHAD_00304 2.29e-55 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body complex protein FliE
KMDGHHAD_00305 1.41e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
KMDGHHAD_00306 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KMDGHHAD_00307 1.32e-173 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KMDGHHAD_00308 1.24e-299 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KMDGHHAD_00309 1.61e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KMDGHHAD_00310 4.77e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
KMDGHHAD_00313 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMDGHHAD_00314 5.55e-212 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
KMDGHHAD_00315 6.5e-215 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KMDGHHAD_00316 1.54e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KMDGHHAD_00317 3.12e-61 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
KMDGHHAD_00318 3.26e-293 - - - D - - - nuclear chromosome segregation
KMDGHHAD_00319 2.21e-179 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMDGHHAD_00320 2.33e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMDGHHAD_00321 9.01e-132 sipS 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KMDGHHAD_00322 6.22e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KMDGHHAD_00323 1.15e-180 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KMDGHHAD_00324 1.52e-120 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KMDGHHAD_00325 4.81e-81 - - - S - - - YlqD protein
KMDGHHAD_00326 4.15e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KMDGHHAD_00327 4.31e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KMDGHHAD_00328 1.81e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KMDGHHAD_00329 4.33e-69 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KMDGHHAD_00330 2.69e-230 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KMDGHHAD_00331 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KMDGHHAD_00332 6.59e-172 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KMDGHHAD_00333 1.64e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMDGHHAD_00334 1.04e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KMDGHHAD_00335 1.77e-209 fabD 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 malonyl CoA-acyl carrier protein transacylase
KMDGHHAD_00336 2.07e-262 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KMDGHHAD_00337 1.03e-126 fapR - - Q - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KMDGHHAD_00338 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KMDGHHAD_00339 1.56e-199 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KMDGHHAD_00340 8.37e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KMDGHHAD_00341 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KMDGHHAD_00342 3.65e-78 yloU - - S - - - protein conserved in bacteria
KMDGHHAD_00343 1.22e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KMDGHHAD_00344 5.94e-161 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KMDGHHAD_00345 6.41e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KMDGHHAD_00346 5.3e-207 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KMDGHHAD_00347 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KMDGHHAD_00348 1.1e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KMDGHHAD_00349 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KMDGHHAD_00350 1.89e-227 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KMDGHHAD_00351 3.5e-107 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMDGHHAD_00352 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMDGHHAD_00353 2.01e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMDGHHAD_00354 4e-40 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KMDGHHAD_00355 2.24e-140 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KMDGHHAD_00356 1.83e-60 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
KMDGHHAD_00357 8.06e-200 yloC - - S - - - stress-induced protein
KMDGHHAD_00358 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KMDGHHAD_00359 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KMDGHHAD_00360 1.1e-209 yocS - - S ko:K03453 - ko00000 -transporter
KMDGHHAD_00361 8.75e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KMDGHHAD_00362 1.17e-115 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
KMDGHHAD_00363 1.02e-13 - - - L ko:K07494 - ko00000 DDE superfamily endonuclease
KMDGHHAD_00364 2.08e-70 - - - L ko:K07499 - ko00000 Transposase
KMDGHHAD_00365 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
KMDGHHAD_00366 9.99e-93 - - - G - - - PTS system fructose IIA component
KMDGHHAD_00367 4.66e-60 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KMDGHHAD_00368 4.9e-93 - - - S - - - Pfam:DUF1399
KMDGHHAD_00369 2.34e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KMDGHHAD_00370 1.73e-07 - - - S - - - YfhE-like protein
KMDGHHAD_00371 4.9e-33 yfhD - - S - - - YfhD-like protein
KMDGHHAD_00372 3.41e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KMDGHHAD_00374 7.62e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KMDGHHAD_00375 0.0 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KMDGHHAD_00376 2.92e-234 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KMDGHHAD_00377 6.22e-140 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase
KMDGHHAD_00378 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMDGHHAD_00379 2.23e-262 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KMDGHHAD_00380 7.71e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KMDGHHAD_00381 8.15e-242 bacG - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KMDGHHAD_00383 5.35e-12 - - - - - - - -
KMDGHHAD_00384 1.29e-113 - - - S - - - Stage II sporulation protein M
KMDGHHAD_00385 6.86e-163 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KMDGHHAD_00387 1.48e-62 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
KMDGHHAD_00389 0.0 - - - - - - - -
KMDGHHAD_00390 4.79e-35 - - - - - - - -
KMDGHHAD_00392 2.3e-80 - - - - - - - -
KMDGHHAD_00393 7.15e-164 - - - V ko:K02003 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KMDGHHAD_00395 3.4e-146 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMDGHHAD_00396 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_00398 2.97e-210 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
KMDGHHAD_00399 8.68e-168 - 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMDGHHAD_00400 3.37e-273 - - - Q - - - Male sterility protein
KMDGHHAD_00401 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KMDGHHAD_00403 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMDGHHAD_00404 9.45e-234 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMDGHHAD_00405 1.34e-280 sgaA - - E - - - COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KMDGHHAD_00406 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMDGHHAD_00407 1.1e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KMDGHHAD_00408 3.55e-280 - - - S - - - HAD-hyrolase-like
KMDGHHAD_00409 6.24e-245 tdcB_1 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KMDGHHAD_00410 6.51e-145 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMDGHHAD_00411 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMDGHHAD_00412 2.51e-259 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KMDGHHAD_00413 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KMDGHHAD_00414 1.27e-249 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KMDGHHAD_00415 1.9e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KMDGHHAD_00416 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KMDGHHAD_00417 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KMDGHHAD_00418 3.55e-312 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KMDGHHAD_00419 9e-194 rsbRD - - T ko:K17763 - ko00000,ko03021 STAS domain
KMDGHHAD_00420 1.37e-308 - - - - - - - -
KMDGHHAD_00421 0.0 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
KMDGHHAD_00422 4.99e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
KMDGHHAD_00423 1.73e-271 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KMDGHHAD_00424 5.46e-279 yhjX - - P ko:K08177 - ko00000,ko02000 Major facilitator superfamily
KMDGHHAD_00425 2.21e-176 - - - T ko:K02477 - ko00000,ko02022 LytTr DNA-binding domain
KMDGHHAD_00426 0.0 ypdA3 2.7.13.3 - T ko:K02478,ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KMDGHHAD_00427 3.34e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
KMDGHHAD_00428 3.31e-97 - - - L - - - Domain of unknown function (DUF4277)
KMDGHHAD_00429 1.57e-214 - - - G ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_00430 2.87e-89 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 - S ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak2
KMDGHHAD_00431 1.87e-158 - 4.1.2.28, 4.3.3.7 - EM ko:K01714,ko:K22397 ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
KMDGHHAD_00432 4.9e-43 - 2.2.1.10, 4.1.2.13 - G ko:K16306 ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 DeoC/LacD family aldolase
KMDGHHAD_00433 7.41e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863,ko:K05878 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dihydroxyacetone kinase DhaK, subunit
KMDGHHAD_00434 5.48e-122 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Triosephosphate isomerase
KMDGHHAD_00435 4.28e-121 - - - K - - - DeoR C terminal sensor domain
KMDGHHAD_00436 0.0 pspF - - KT - - - Transcriptional regulator
KMDGHHAD_00437 0.0 - 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_00438 0.0 - 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 AMP-dependent synthetase
KMDGHHAD_00439 2.89e-272 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KMDGHHAD_00440 4.61e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
KMDGHHAD_00441 6.17e-22 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
KMDGHHAD_00442 6.41e-207 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
KMDGHHAD_00443 3.1e-172 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
KMDGHHAD_00444 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMDGHHAD_00445 2.09e-104 - - - K - - - Acetyltransferase (GNAT) domain
KMDGHHAD_00448 9.27e-127 - - - O - - - HI0933-like protein
KMDGHHAD_00450 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMDGHHAD_00451 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMDGHHAD_00452 1.89e-286 ywdJ - - F - - - Xanthine uracil
KMDGHHAD_00453 7.85e-216 - - - S ko:K07090 - ko00000 membrane transporter protein
KMDGHHAD_00455 1.71e-301 - - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_00456 6.35e-175 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
KMDGHHAD_00458 2.63e-223 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KMDGHHAD_00459 1.39e-231 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase DhaK, subunit
KMDGHHAD_00460 1.64e-129 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
KMDGHHAD_00461 1.85e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
KMDGHHAD_00462 0.0 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMDGHHAD_00463 2.79e-176 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
KMDGHHAD_00464 7.07e-97 ywnF - - S - - - Family of unknown function (DUF5392)
KMDGHHAD_00466 7.79e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KMDGHHAD_00467 0.0 yfiG - - U ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMDGHHAD_00468 2.04e-110 - - - G ko:K02755,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
KMDGHHAD_00469 1.16e-76 - - - S - - - Nitrous oxide-stimulated promoter
KMDGHHAD_00470 1.11e-195 yxeH - - S - - - hydrolases of the HAD superfamily
KMDGHHAD_00471 9.8e-124 - - - D - - - Hemerythrin HHE cation binding
KMDGHHAD_00472 2.13e-256 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KMDGHHAD_00473 7.36e-172 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_00474 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KMDGHHAD_00475 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
KMDGHHAD_00476 9.51e-47 yoeD - - G - - - Helix-turn-helix domain
KMDGHHAD_00477 1.89e-150 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KMDGHHAD_00478 5.75e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KMDGHHAD_00479 7.63e-117 - 1.8.5.2 - S ko:K16937 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000 DoxX
KMDGHHAD_00480 7.6e-139 - - - C - - - Nitroreductase family
KMDGHHAD_00481 0.0 snf - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMDGHHAD_00482 5.85e-24 macB1 - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KMDGHHAD_00483 9.58e-214 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KMDGHHAD_00484 2.06e-157 yhcW - - S ko:K07025 - ko00000 hydrolase
KMDGHHAD_00485 9.52e-212 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KMDGHHAD_00486 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMDGHHAD_00487 6.98e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KMDGHHAD_00488 6.37e-42 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KMDGHHAD_00489 2.4e-168 ycdF 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Short-chain dehydrogenase reductase sdr
KMDGHHAD_00490 1.23e-188 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KMDGHHAD_00491 1.08e-111 - - - - - - - -
KMDGHHAD_00492 8.19e-96 - 3.4.21.121 - O ko:K20755 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
KMDGHHAD_00493 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KMDGHHAD_00494 6.68e-206 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMDGHHAD_00495 2.92e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
KMDGHHAD_00496 2.27e-69 - - - S - - - Iron-sulphur cluster biosynthesis
KMDGHHAD_00497 1.06e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KMDGHHAD_00498 1.49e-169 - - - K - - - helix_turn_helix, arabinose operon control protein
KMDGHHAD_00499 8.72e-298 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KMDGHHAD_00500 2e-282 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMDGHHAD_00501 3.14e-189 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMDGHHAD_00502 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
KMDGHHAD_00503 3.84e-278 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KMDGHHAD_00504 3.17e-277 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KMDGHHAD_00505 1.34e-09 - - - S - - - ABC-2 family transporter protein
KMDGHHAD_00506 1.26e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KMDGHHAD_00507 2.04e-226 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the SIS family. GutQ KpsF subfamily
KMDGHHAD_00508 5.7e-199 kdsA 2.5.1.55 - M ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the KdsA family
KMDGHHAD_00509 0.0 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
KMDGHHAD_00510 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KMDGHHAD_00511 9.22e-317 celD 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMDGHHAD_00512 1.58e-106 - - - - - - - -
KMDGHHAD_00513 4.19e-69 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KMDGHHAD_00514 1.02e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMDGHHAD_00515 2.01e-89 - - - S - - - Protein of unknown function (DUF2512)
KMDGHHAD_00516 0.0 wprA - - O ko:K13274,ko:K20276 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KMDGHHAD_00517 2.97e-12 - - - S - - - Protein of unknown function (DUF1659)
KMDGHHAD_00518 1.62e-16 - - - S - - - Protein of unknown function (DUF2922)
KMDGHHAD_00519 3.26e-23 - - - S - - - YvrJ protein family
KMDGHHAD_00520 3.21e-47 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KMDGHHAD_00521 4.46e-168 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KMDGHHAD_00522 2.07e-280 - - - EGP - - - Major facilitator superfamily
KMDGHHAD_00523 7.6e-216 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KMDGHHAD_00525 3.37e-79 - - - - - - - -
KMDGHHAD_00526 7.28e-290 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMDGHHAD_00527 2.66e-157 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
KMDGHHAD_00528 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KMDGHHAD_00529 1.43e-30 - - - S - - - Zinc-ribbon containing domain
KMDGHHAD_00530 9.45e-315 - - - E ko:K03294 - ko00000 Amino acid permease
KMDGHHAD_00531 4.24e-216 - 3.5.1.4 - C ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Acetamidase
KMDGHHAD_00533 9.79e-168 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
KMDGHHAD_00534 8.3e-171 - - - T - - - Histidine kinase
KMDGHHAD_00535 9.2e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
KMDGHHAD_00536 1.02e-81 - - - K - - - transcriptional
KMDGHHAD_00537 0.0 - 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_00538 0.0 - - - I - - - Acyl-CoA dehydrogenase, middle domain
KMDGHHAD_00539 2.44e-213 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_00540 3.71e-197 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
KMDGHHAD_00541 4.37e-287 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMDGHHAD_00542 1.14e-91 yxiE - - T - - - Belongs to the universal stress protein A family
KMDGHHAD_00543 4.69e-39 - - - - - - - -
KMDGHHAD_00544 1.49e-98 - - - - - - - -
KMDGHHAD_00545 2.95e-287 yfkA - - S - - - YfkB-like domain
KMDGHHAD_00547 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
KMDGHHAD_00548 7.16e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KMDGHHAD_00549 5.68e-114 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KMDGHHAD_00550 3.37e-112 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KMDGHHAD_00551 5.9e-232 ykvZ - - K - - - Transcriptional regulator
KMDGHHAD_00552 5.86e-122 hxlB 4.1.2.43, 5.3.1.27 - M ko:K08093,ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 arabinose-5-phosphate isomerase activity
KMDGHHAD_00553 1.84e-189 ykrA - - S - - - hydrolases of the HAD superfamily
KMDGHHAD_00555 6.64e-185 - 3.1.1.1 - S ko:K03928 - ko00000,ko01000 BAAT / Acyl-CoA thioester hydrolase C terminal
KMDGHHAD_00556 2.1e-85 ubiE2 - - Q - - - Methyltransferase domain
KMDGHHAD_00557 0.0 ubiE2 - - Q - - - Methyltransferase domain
KMDGHHAD_00558 1.97e-230 - - - C - - - Aldo/keto reductase family
KMDGHHAD_00559 1.25e-71 - - - M - - - Spore coat protein
KMDGHHAD_00560 8.74e-58 - - - M - - - Spore coat protein
KMDGHHAD_00561 1.9e-177 - - - I - - - alpha/beta hydrolase fold
KMDGHHAD_00562 6.41e-197 morA - - S - - - Aldo/keto reductase family
KMDGHHAD_00563 1.31e-129 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
KMDGHHAD_00564 1.62e-314 yhaO - - L ko:K03547 - ko00000,ko03400 Calcineurin-like phosphoesterase superfamily domain
KMDGHHAD_00565 0.0 - - - L - - - AAA domain
KMDGHHAD_00566 1.5e-196 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KMDGHHAD_00567 1.88e-315 - - - V - - - Mate efflux family protein
KMDGHHAD_00569 3.38e-81 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KMDGHHAD_00570 2.84e-57 - - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KMDGHHAD_00571 1.7e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
KMDGHHAD_00572 1.41e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KMDGHHAD_00573 3.27e-134 - 4.1.3.17 - H ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 ko00000,ko00001,ko01000 Methyltransferase
KMDGHHAD_00574 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
KMDGHHAD_00575 3.05e-67 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMDGHHAD_00576 0.0 - 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMDGHHAD_00577 3.29e-187 ubiE - - Q - - - Methyltransferase type 11
KMDGHHAD_00578 1.53e-52 - - - - - - - -
KMDGHHAD_00579 8.28e-221 - - - S - - - Acetyl xylan esterase (AXE1)
KMDGHHAD_00580 2.94e-189 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KMDGHHAD_00581 1.23e-40 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
KMDGHHAD_00582 2.81e-57 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
KMDGHHAD_00584 6.44e-49 csfB - - S - - - Inhibitor of sigma-G Gin
KMDGHHAD_00585 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
KMDGHHAD_00586 2.41e-155 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMDGHHAD_00587 3.54e-73 yaaQ - - S - - - protein conserved in bacteria
KMDGHHAD_00588 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
KMDGHHAD_00589 1.99e-237 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KMDGHHAD_00590 3.27e-191 yaaT - - S - - - stage 0 sporulation protein
KMDGHHAD_00591 1.06e-87 yabA - - L - - - Involved in initiation control of chromosome replication
KMDGHHAD_00592 8.7e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
KMDGHHAD_00593 2.98e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KMDGHHAD_00594 1.53e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KMDGHHAD_00595 6.07e-77 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
KMDGHHAD_00596 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMDGHHAD_00597 4.68e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
KMDGHHAD_00598 9.16e-138 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMDGHHAD_00599 2.94e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KMDGHHAD_00600 1.66e-213 yabG - - S ko:K06436 - ko00000 peptidase
KMDGHHAD_00601 8.34e-51 veg - - S - - - protein conserved in bacteria
KMDGHHAD_00602 4.78e-46 sspF - - S ko:K06423 - ko00000 DNA topological change
KMDGHHAD_00603 6.21e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KMDGHHAD_00604 1.24e-198 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KMDGHHAD_00605 5.31e-82 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
KMDGHHAD_00606 2.1e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KMDGHHAD_00608 2.95e-92 - - - S - - - Psort location CytoplasmicMembrane, score
KMDGHHAD_00609 9.05e-55 - - - V ko:K02003 - ko00000,ko00002,ko02000 Abc transporter
KMDGHHAD_00610 2.07e-106 - - - - - - - -
KMDGHHAD_00611 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KMDGHHAD_00612 1.32e-224 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMDGHHAD_00613 5.06e-144 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KMDGHHAD_00614 1.38e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KMDGHHAD_00615 1.79e-50 yabK - - S - - - Peptide ABC transporter permease
KMDGHHAD_00616 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KMDGHHAD_00617 2.8e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
KMDGHHAD_00618 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMDGHHAD_00619 8.25e-249 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KMDGHHAD_00620 1.58e-55 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KMDGHHAD_00621 1.23e-67 yabP - - S - - - Sporulation protein YabP
KMDGHHAD_00622 1.39e-141 yabQ - - S - - - spore cortex biosynthesis protein
KMDGHHAD_00623 7.06e-79 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KMDGHHAD_00624 7.71e-85 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KMDGHHAD_00626 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
KMDGHHAD_00627 1.72e-162 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KMDGHHAD_00628 3.24e-225 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
KMDGHHAD_00629 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KMDGHHAD_00630 2.89e-123 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KMDGHHAD_00631 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMDGHHAD_00632 9.15e-183 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KMDGHHAD_00633 5.07e-204 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KMDGHHAD_00634 2.18e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KMDGHHAD_00635 2.74e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KMDGHHAD_00636 1.87e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KMDGHHAD_00637 5.73e-125 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KMDGHHAD_00638 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KMDGHHAD_00639 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KMDGHHAD_00640 1.2e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMDGHHAD_00641 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KMDGHHAD_00642 2.76e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KMDGHHAD_00643 5.15e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMDGHHAD_00644 3.83e-147 emrA - - V - - - Barrel-sandwich domain of CusB or HlyD membrane-fusion
KMDGHHAD_00645 0.0 yhcA5 - - EGP - - - the major facilitator superfamily
KMDGHHAD_00646 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
KMDGHHAD_00648 9.73e-317 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KMDGHHAD_00649 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KMDGHHAD_00651 1e-222 ybaS - - S - - - Na -dependent transporter
KMDGHHAD_00652 3.52e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KMDGHHAD_00653 1.24e-298 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KMDGHHAD_00654 1.28e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Short-chain dehydrogenase reductase sdr
KMDGHHAD_00655 3.63e-103 - - - - - - - -
KMDGHHAD_00656 1.24e-94 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_00657 2.1e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KMDGHHAD_00658 4.32e-283 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KMDGHHAD_00659 4.88e-162 yrrB - - S - - - COG0457 FOG TPR repeat
KMDGHHAD_00660 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KMDGHHAD_00662 1.52e-79 pdh 1.4.1.20 - E ko:K00270 ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130 ko00000,ko00001,ko01000 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KMDGHHAD_00663 3.71e-76 - - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
KMDGHHAD_00664 1.07e-87 yndM - - S - - - Protein of unknown function (DUF2512)
KMDGHHAD_00665 3.5e-40 yrzR - - - - - - -
KMDGHHAD_00667 8.49e-245 yrrI - - S - - - AI-2E family transporter
KMDGHHAD_00668 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KMDGHHAD_00669 2.76e-59 yrzL - - S - - - Belongs to the UPF0297 family
KMDGHHAD_00670 7.49e-91 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KMDGHHAD_00671 9.07e-61 yrzB - - S - - - Belongs to the UPF0473 family
KMDGHHAD_00672 6.42e-262 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMDGHHAD_00673 9.09e-149 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
KMDGHHAD_00674 3.05e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KMDGHHAD_00675 7.42e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMDGHHAD_00676 2.18e-99 yrrS - - S - - - Protein of unknown function (DUF1510)
KMDGHHAD_00677 2.82e-40 yrzA - - S - - - Protein of unknown function (DUF2536)
KMDGHHAD_00678 7.42e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KMDGHHAD_00679 2.49e-11 - - - S - - - YrhC-like protein
KMDGHHAD_00681 3.96e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
KMDGHHAD_00682 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
KMDGHHAD_00684 3.64e-162 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMDGHHAD_00685 3.27e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMDGHHAD_00686 7.73e-22 sda - - S ko:K06371 - ko00000 Sporulation inhibitor A
KMDGHHAD_00687 9.03e-203 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KMDGHHAD_00688 2.98e-152 - - - S - - - VIT family
KMDGHHAD_00689 3.46e-95 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMDGHHAD_00690 4.78e-79 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMDGHHAD_00691 1.54e-82 lemA - - S ko:K03744 - ko00000 LemA family
KMDGHHAD_00692 1.19e-137 - - - S ko:K06872 - ko00000 TPM domain
KMDGHHAD_00694 8.83e-123 stoA - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KMDGHHAD_00695 2.05e-42 - - - S ko:K08982 - ko00000 Short C-terminal domain
KMDGHHAD_00696 1.32e-92 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KMDGHHAD_00697 3.13e-287 mco - - Q - - - multicopper oxidases
KMDGHHAD_00698 4.05e-246 ysfB - - KT ko:K02647 - ko00000,ko03000 regulator
KMDGHHAD_00699 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
KMDGHHAD_00700 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
KMDGHHAD_00701 1.11e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KMDGHHAD_00702 2.28e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KMDGHHAD_00703 3.2e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KMDGHHAD_00704 2.57e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
KMDGHHAD_00705 2.28e-137 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KMDGHHAD_00706 9.63e-130 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KMDGHHAD_00707 1.02e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KMDGHHAD_00708 3.18e-189 - - - S - - - Methyltransferase domain
KMDGHHAD_00709 1.62e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMDGHHAD_00710 2.72e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KMDGHHAD_00711 2.64e-146 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 COG2131 Deoxycytidylate deaminase
KMDGHHAD_00712 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KMDGHHAD_00713 1.18e-11 - - - S - - - YqzM-like protein
KMDGHHAD_00714 4.52e-238 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KMDGHHAD_00715 3.34e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KMDGHHAD_00716 1.19e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KMDGHHAD_00717 1.12e-286 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
KMDGHHAD_00718 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KMDGHHAD_00719 9.03e-279 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KMDGHHAD_00720 1.59e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KMDGHHAD_00721 3.09e-123 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KMDGHHAD_00722 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KMDGHHAD_00723 7.38e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KMDGHHAD_00724 1.32e-220 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
KMDGHHAD_00725 1.14e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KMDGHHAD_00726 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
KMDGHHAD_00727 3.37e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KMDGHHAD_00728 9.76e-64 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KMDGHHAD_00729 3.56e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KMDGHHAD_00730 1.07e-93 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
KMDGHHAD_00731 1.1e-60 yqfC - - S - - - sporulation protein YqfC
KMDGHHAD_00732 5.57e-290 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
KMDGHHAD_00733 4.09e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
KMDGHHAD_00734 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
KMDGHHAD_00735 8.37e-108 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KMDGHHAD_00736 6.81e-86 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KMDGHHAD_00737 3.22e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KMDGHHAD_00738 8.43e-13 - - - S - - - YqzL-like protein
KMDGHHAD_00739 1.76e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KMDGHHAD_00740 4.15e-145 ccpN - - K - - - CBS domain
KMDGHHAD_00741 3.84e-190 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KMDGHHAD_00742 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KMDGHHAD_00743 4.85e-258 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KMDGHHAD_00744 1.01e-112 - - - - - - - -
KMDGHHAD_00745 1.79e-84 cccA - - C ko:K13300 - ko00000 Cytochrome C oxidase, cbb3-type, subunit III
KMDGHHAD_00746 4.46e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KMDGHHAD_00747 2.45e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KMDGHHAD_00748 2.81e-231 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KMDGHHAD_00749 1.66e-09 yqfQ - - S - - - YqfQ-like protein
KMDGHHAD_00751 7.05e-306 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KMDGHHAD_00752 2.19e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KMDGHHAD_00753 3.61e-221 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KMDGHHAD_00754 1.94e-27 yqfT - - S - - - Protein of unknown function (DUF2624)
KMDGHHAD_00755 5.46e-183 zurA - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KMDGHHAD_00756 5.71e-181 zurM - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KMDGHHAD_00757 1.33e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
KMDGHHAD_00758 1.48e-146 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
KMDGHHAD_00759 1.11e-259 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KMDGHHAD_00760 4.46e-72 - - - NU - - - Tfp pilus assembly protein FimV
KMDGHHAD_00761 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KMDGHHAD_00762 5.85e-275 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
KMDGHHAD_00763 0.0 pbpA - - M ko:K21465 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KMDGHHAD_00764 1.33e-70 yqzD - - - - - - -
KMDGHHAD_00765 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KMDGHHAD_00767 7.01e-267 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KMDGHHAD_00768 1.93e-39 yqgQ - - S - - - protein conserved in bacteria
KMDGHHAD_00769 5.87e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KMDGHHAD_00770 1.57e-30 yqgW - - S - - - Protein of unknown function (DUF2759)
KMDGHHAD_00771 2.01e-159 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KMDGHHAD_00772 1.31e-48 B4168_0554 - - S - - - Protein of unknown function (DUF2626)
KMDGHHAD_00773 1.29e-168 - - - K - - - Helix-turn-helix domain
KMDGHHAD_00774 8.22e-269 comGA - - NU ko:K02243,ko:K02652 - ko00000,ko00002,ko02035,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KMDGHHAD_00775 3.12e-223 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
KMDGHHAD_00776 1.67e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KMDGHHAD_00777 2.1e-99 comGD - - NU ko:K02246 - ko00000,ko00002,ko02044 COG2165 Type II secretory pathway, pseudopilin PulG
KMDGHHAD_00779 1.27e-109 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 COG4940 Competence protein ComGF
KMDGHHAD_00780 5.35e-81 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
KMDGHHAD_00781 2.04e-129 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KMDGHHAD_00782 3.69e-14 yqzE - - S - - - YqzE-like protein
KMDGHHAD_00783 5.31e-200 yqhG - - S - - - Bacterial protein YqhG of unknown function
KMDGHHAD_00784 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMDGHHAD_00785 1.95e-271 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
KMDGHHAD_00786 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMDGHHAD_00787 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMDGHHAD_00788 3.28e-87 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
KMDGHHAD_00789 2.74e-205 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KMDGHHAD_00790 0.0 nrdA 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
KMDGHHAD_00791 5.65e-130 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KMDGHHAD_00792 7.88e-34 paaG 5.3.3.18 - I ko:K15866 ko00360,ko01120,map00360,map01120 ko00000,ko00001,ko01000 Enoyl-CoA hydratase
KMDGHHAD_00793 0.0 - 1.2.1.3, 1.2.1.8 - C ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMDGHHAD_00794 2.32e-196 hbd 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
KMDGHHAD_00795 1.06e-279 pcaF 2.3.1.174, 2.3.1.223 - I ko:K02615 ko00360,ko01120,map00360,map01120 ko00000,ko00001,ko01000 Belongs to the thiolase family
KMDGHHAD_00796 2.68e-226 paaX - - K ko:K02616 - ko00000,ko03000 PaaX-like protein
KMDGHHAD_00797 1.07e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KMDGHHAD_00798 1.26e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KMDGHHAD_00799 9.04e-18 yqhP - - - - - - -
KMDGHHAD_00800 2.32e-207 yqhQ - - S - - - Protein of unknown function (DUF1385)
KMDGHHAD_00801 2.13e-111 yqhR - - S - - - Conserved membrane protein YqhR
KMDGHHAD_00802 1.78e-102 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KMDGHHAD_00803 6.2e-242 yqhT 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KMDGHHAD_00804 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KMDGHHAD_00805 1.32e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
KMDGHHAD_00806 2.42e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
KMDGHHAD_00807 3.6e-38 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
KMDGHHAD_00808 2.48e-78 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
KMDGHHAD_00809 2.12e-258 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
KMDGHHAD_00810 2.58e-139 spoIIIAF - - S ko:K06395 - ko00000 stage III sporulation protein AF
KMDGHHAD_00811 1.55e-142 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
KMDGHHAD_00812 1.12e-110 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
KMDGHHAD_00813 2.67e-106 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMDGHHAD_00814 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KMDGHHAD_00815 7.54e-90 yqhY - - S - - - protein conserved in bacteria
KMDGHHAD_00816 3.5e-84 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMDGHHAD_00817 3.88e-203 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KMDGHHAD_00818 3.18e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMDGHHAD_00819 4.77e-42 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMDGHHAD_00820 1.52e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KMDGHHAD_00821 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMDGHHAD_00822 4.13e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
KMDGHHAD_00823 2.26e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KMDGHHAD_00824 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KMDGHHAD_00825 5.17e-308 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
KMDGHHAD_00826 3.14e-182 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KMDGHHAD_00827 1.1e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KMDGHHAD_00828 1.31e-48 yqzF - - S - - - Protein of unknown function (DUF2627)
KMDGHHAD_00829 0.0 bkdR - - KT - - - Transcriptional regulator
KMDGHHAD_00830 1.39e-64 - - - T - - - transcription factor binding
KMDGHHAD_00831 1.53e-265 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KMDGHHAD_00832 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMDGHHAD_00833 1.52e-239 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMDGHHAD_00834 8.08e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMDGHHAD_00835 4.55e-285 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMDGHHAD_00836 2.63e-211 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
KMDGHHAD_00837 5.17e-99 yqiW - - S - - - Belongs to the UPF0403 family
KMDGHHAD_00838 1.08e-122 yqjB - - S - - - protein conserved in bacteria
KMDGHHAD_00840 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMDGHHAD_00841 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_00842 0.0 - - - EGP - - - the major facilitator superfamily
KMDGHHAD_00843 2.69e-141 - - - K - - - Bacterial regulatory proteins, tetR family
KMDGHHAD_00844 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KMDGHHAD_00845 1.95e-176 lppC - - M - - - 5'-nucleotidase, lipoprotein e(P4)
KMDGHHAD_00848 1.67e-270 ydbM - - I - - - acyl-CoA dehydrogenase
KMDGHHAD_00849 2.69e-23 - - - I - - - acyl-CoA dehydrogenase activity
KMDGHHAD_00850 2.16e-21 - - - - - - - -
KMDGHHAD_00851 1.46e-283 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMDGHHAD_00852 8.2e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KMDGHHAD_00853 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KMDGHHAD_00854 2.6e-260 mro 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
KMDGHHAD_00855 3.05e-234 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_00856 1.15e-43 ydjO - - S - - - Cold-inducible protein YdjO
KMDGHHAD_00857 9.05e-22 - - - - - - - -
KMDGHHAD_00859 2.63e-207 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
KMDGHHAD_00860 6.3e-91 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMDGHHAD_00861 1.52e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KMDGHHAD_00862 6.09e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KMDGHHAD_00863 0.0 bmr3_1 - - P ko:K18935 - ko00000,ko02000 Major facilitator superfamily
KMDGHHAD_00864 4.41e-270 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KMDGHHAD_00865 1.69e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMDGHHAD_00866 5e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
KMDGHHAD_00867 3.01e-251 cwlS - CBM50 M ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KMDGHHAD_00868 1.28e-313 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KMDGHHAD_00869 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
KMDGHHAD_00870 3.9e-225 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KMDGHHAD_00871 2.07e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
KMDGHHAD_00872 5.7e-262 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KMDGHHAD_00873 2.8e-159 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMDGHHAD_00874 0.0 yfnA - - E ko:K03294 - ko00000 amino acid
KMDGHHAD_00875 3.3e-198 degV - - S - - - protein conserved in bacteria
KMDGHHAD_00877 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KMDGHHAD_00878 1.63e-171 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
KMDGHHAD_00879 2.2e-91 yvyF - - S - - - flagellar protein
KMDGHHAD_00880 1.24e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
KMDGHHAD_00881 2.9e-99 yvyG - - NOU - - - FlgN protein
KMDGHHAD_00882 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
KMDGHHAD_00883 1.7e-204 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
KMDGHHAD_00884 9.57e-106 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KMDGHHAD_00885 3.42e-45 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KMDGHHAD_00886 1.96e-31 - - - S - - - Nucleotidyltransferase domain
KMDGHHAD_00887 1.67e-123 - - - U - - - SEC-C motif
KMDGHHAD_00890 3.37e-218 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMDGHHAD_00892 1.29e-170 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KMDGHHAD_00893 5.63e-77 ytzH - - S - - - YtzH-like protein
KMDGHHAD_00894 2.25e-201 ytmP - - M - - - Phosphotransferase
KMDGHHAD_00895 8.11e-196 ytlQ - - - - - - -
KMDGHHAD_00896 4.8e-139 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KMDGHHAD_00898 4.89e-204 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KMDGHHAD_00899 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
KMDGHHAD_00900 9e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
KMDGHHAD_00901 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMDGHHAD_00902 9.36e-36 yteV - - S - - - Sporulation protein Cse60
KMDGHHAD_00905 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KMDGHHAD_00906 4.49e-236 yttB - - EGP - - - Major facilitator superfamily
KMDGHHAD_00907 4.76e-56 ytzC - - S - - - Protein of unknown function (DUF2524)
KMDGHHAD_00908 1.37e-134 ytqB - - J - - - Putative rRNA methylase
KMDGHHAD_00909 7.59e-269 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
KMDGHHAD_00910 2.16e-197 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
KMDGHHAD_00911 1.29e-107 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KMDGHHAD_00912 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KMDGHHAD_00913 1.85e-282 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KMDGHHAD_00914 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KMDGHHAD_00915 1.28e-89 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KMDGHHAD_00916 1.51e-261 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KMDGHHAD_00917 4.85e-130 ywqN - - S - - - NAD(P)H-dependent
KMDGHHAD_00918 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KMDGHHAD_00919 1.4e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KMDGHHAD_00920 2.91e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMDGHHAD_00921 1.02e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMDGHHAD_00922 1.64e-108 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KMDGHHAD_00923 2.31e-52 - - - - - - - -
KMDGHHAD_00924 7.57e-103 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KMDGHHAD_00925 1.27e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KMDGHHAD_00927 3.6e-210 adcA - - P ko:K09815,ko:K09818 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KMDGHHAD_00928 5.75e-33 - - - S - - - Domain of Unknown Function (DUF1540)
KMDGHHAD_00929 7.56e-266 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KMDGHHAD_00930 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KMDGHHAD_00931 3.06e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMDGHHAD_00932 3.41e-189 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KMDGHHAD_00933 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KMDGHHAD_00934 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KMDGHHAD_00935 1.25e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KMDGHHAD_00941 4.18e-237 csd1 - - S ko:K19117 - ko00000,ko02048 CRISPR-associated protein, Csd1 family
KMDGHHAD_00942 3.27e-27 - - - L ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
KMDGHHAD_00943 0.0 ybeC - - E - - - amino acid
KMDGHHAD_00944 4.43e-224 - - - K - - - cell envelope-related transcriptional attenuator
KMDGHHAD_00946 4.78e-79 - - - - - - - -
KMDGHHAD_00947 2.67e-221 ydhF - - S - - - Oxidoreductase
KMDGHHAD_00948 4.73e-205 - - - S - - - transposase or invertase
KMDGHHAD_00949 3.94e-25 - - - S - - - transposase or invertase
KMDGHHAD_00951 1.57e-68 - - - S - - - Domain of unknown function (DUF3870)
KMDGHHAD_00952 1.32e-291 - 1.3.99.32 - I ko:K16173 ko00362,ko01120,map00362,map01120 ko00000,ko00001,ko01000 Acyl-CoA dehydrogenase, N-terminal domain
KMDGHHAD_00953 6.98e-286 - 2.8.3.19 - C ko:K18702 - ko00000,ko01000 acyl-CoA transferases carnitine dehydratase
KMDGHHAD_00954 2.17e-243 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
KMDGHHAD_00955 1.33e-273 - - - EGP - - - Major facilitator superfamily
KMDGHHAD_00956 0.0 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
KMDGHHAD_00957 5.21e-71 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMDGHHAD_00958 1.39e-70 ptcA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS cellobiose transporter subunit IIA
KMDGHHAD_00959 1.47e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
KMDGHHAD_00960 2.93e-298 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMDGHHAD_00961 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 MFS/sugar transport protein
KMDGHHAD_00963 0.0 - - - E - - - Amino acid permease
KMDGHHAD_00964 0.0 - 3.2.1.37 GH43 K ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 helix_turn_helix, arabinose operon control protein
KMDGHHAD_00965 6.72e-286 kbl 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMDGHHAD_00966 1.85e-238 - - - GM - - - GDP-mannose 4,6 dehydratase
KMDGHHAD_00967 1.38e-97 ywoH - - K - - - transcriptional
KMDGHHAD_00968 7.34e-271 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_00969 1.66e-222 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_00971 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
KMDGHHAD_00972 1.41e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMDGHHAD_00973 6.78e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMDGHHAD_00974 5.03e-148 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMDGHHAD_00975 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMDGHHAD_00976 8.34e-127 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KMDGHHAD_00977 5.39e-130 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KMDGHHAD_00978 9.78e-257 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KMDGHHAD_00979 4.33e-62 - - - - - - - -
KMDGHHAD_00980 8.6e-138 yjlB - - S - - - Cupin domain
KMDGHHAD_00981 5.58e-181 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
KMDGHHAD_00982 9.08e-175 glx2 - - S - - - Metallo-beta-lactamase superfamily
KMDGHHAD_00985 1.17e-95 ywnA - - K - - - Transcriptional regulator
KMDGHHAD_00986 1.83e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
KMDGHHAD_00987 4.4e-122 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KMDGHHAD_00988 7.06e-126 padR - - K - - - transcriptional
KMDGHHAD_00989 5.59e-78 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_00990 3.96e-163 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_00991 2.73e-163 - - - - - - - -
KMDGHHAD_00994 0.0 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
KMDGHHAD_00995 2.55e-64 - - - L - - - deoxyribonuclease I activity
KMDGHHAD_00996 0.0 citT_1 - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KMDGHHAD_00997 6.15e-287 - 1.13.11.4 - Q ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 AraC-like ligand binding domain
KMDGHHAD_00998 3.62e-210 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
KMDGHHAD_00999 3.82e-183 - - - K - - - helix_turn_helix isocitrate lyase regulation
KMDGHHAD_01000 2.52e-283 - - - EGP ko:K05548 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
KMDGHHAD_01001 6.71e-211 - - - QT - - - Domain present in phytochromes and cGMP-specific phosphodiesterases.
KMDGHHAD_01002 9.08e-201 hbd 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KMDGHHAD_01003 2.43e-42 crt 4.2.1.17 - I ko:K01715 ko00650,ko01200,map00650,map01200 ko00000,ko00001,ko01000 Enoyl-CoA hydratase/isomerase
KMDGHHAD_01004 1.72e-121 crt 4.2.1.17 - I ko:K01715 ko00650,ko01200,map00650,map01200 ko00000,ko00001,ko01000 Enoyl-CoA hydratase/isomerase
KMDGHHAD_01005 3.02e-275 thlA 2.3.1.16, 2.3.1.9 - I ko:K00626,ko:K07508 ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KMDGHHAD_01006 0.0 - 6.2.1.3, 6.2.1.34, 6.2.1.48 - IQ ko:K00666,ko:K01897,ko:K02182,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_01007 9.88e-91 - - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KMDGHHAD_01008 2.16e-194 - 1.14.13.127 - CH ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 ko00000,ko00001,ko00002,ko01000 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KMDGHHAD_01009 7.73e-74 - - - - - - - -
KMDGHHAD_01010 4.4e-173 - - - K - - - helix_turn_helix isocitrate lyase regulation
KMDGHHAD_01011 6.59e-227 - 3.7.1.5 - Q ko:K16164 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KMDGHHAD_01012 9.62e-116 - - - S - - - DinB superfamily
KMDGHHAD_01013 1.51e-287 - 1.13.11.4 - Q ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 Cupin domain
KMDGHHAD_01014 2.52e-262 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KMDGHHAD_01015 6.56e-253 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KMDGHHAD_01016 3.91e-217 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KMDGHHAD_01017 9.7e-253 - - - T - - - Histidine kinase
KMDGHHAD_01018 2.8e-150 yfiK - - K - - - Regulator
KMDGHHAD_01019 2.47e-272 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_01020 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KMDGHHAD_01021 0.000216 - - - D - - - nuclear chromosome segregation
KMDGHHAD_01022 3.52e-293 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KMDGHHAD_01023 3.05e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
KMDGHHAD_01024 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMDGHHAD_01025 7.54e-284 gltT - - C - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMDGHHAD_01026 4.08e-220 corA - - P ko:K03284 - ko00000,ko02000 Mg2 transporter protein CorA family protein
KMDGHHAD_01029 1.53e-306 panF - - H ko:K14392 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMDGHHAD_01030 7.03e-62 - - - S - - - Sodium pantothenate symporter
KMDGHHAD_01031 3.21e-212 - 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KMDGHHAD_01032 0.0 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KMDGHHAD_01033 9.66e-24 - - - S - - - Protein of unknown function (DUF4064)
KMDGHHAD_01034 1.46e-30 - - - E - - - Belongs to the arginase family
KMDGHHAD_01035 1.84e-189 - - - E - - - Belongs to the arginase family
KMDGHHAD_01036 1.22e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KMDGHHAD_01037 9.28e-249 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KMDGHHAD_01038 1.47e-214 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KMDGHHAD_01039 3.42e-180 - - - P ko:K02049,ko:K15600 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_01040 1.47e-243 M1-596 - - P ko:K02051,ko:K15598 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KMDGHHAD_01041 8.33e-183 - - - P ko:K15599 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
KMDGHHAD_01042 1.4e-154 - - - S - - - Thiamine-binding protein
KMDGHHAD_01044 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
KMDGHHAD_01045 6.59e-106 - - - S - - - Heat induced stress protein YflT
KMDGHHAD_01046 1.92e-211 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KMDGHHAD_01047 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
KMDGHHAD_01048 1.13e-270 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KMDGHHAD_01049 2.74e-84 manO - - S - - - Domain of unknown function (DUF956)
KMDGHHAD_01050 1.04e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KMDGHHAD_01051 3.45e-174 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KMDGHHAD_01052 9.73e-228 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
KMDGHHAD_01053 4.91e-110 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KMDGHHAD_01054 0.0 levR - - K - - - PTS system fructose IIA component
KMDGHHAD_01055 0.0 - - - S - - - ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMDGHHAD_01056 1.69e-258 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
KMDGHHAD_01057 2.13e-64 yqgV - - S - - - Thiamine-binding protein
KMDGHHAD_01058 0.0 pip - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KMDGHHAD_01059 7.71e-128 - - - KT - - - HD domain
KMDGHHAD_01061 2.23e-155 yabE - - S ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 3D domain
KMDGHHAD_01062 3.52e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KMDGHHAD_01064 0.0 ppc 4.1.1.31 - C ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KMDGHHAD_01065 1.18e-41 - - - - - - - -
KMDGHHAD_01066 3.72e-152 cls2 - - I - - - PLD-like domain
KMDGHHAD_01067 6.96e-74 ydbP - - CO - - - Thioredoxin
KMDGHHAD_01068 1.29e-261 - - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KMDGHHAD_01069 3.32e-74 yusN - - M - - - Coat F domain
KMDGHHAD_01070 8.24e-56 - - - - - - - -
KMDGHHAD_01071 3.69e-21 - - - S - - - YuzL-like protein
KMDGHHAD_01072 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
KMDGHHAD_01073 5.89e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
KMDGHHAD_01074 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KMDGHHAD_01075 3.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KMDGHHAD_01076 4.68e-82 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KMDGHHAD_01077 6.34e-66 yusE - - CO - - - Thioredoxin
KMDGHHAD_01079 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KMDGHHAD_01080 5e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KMDGHHAD_01081 1.58e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMDGHHAD_01082 2.18e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
KMDGHHAD_01083 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
KMDGHHAD_01084 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KMDGHHAD_01085 3.71e-64 yunC - - S - - - Domain of unknown function (DUF1805)
KMDGHHAD_01086 8.63e-165 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
KMDGHHAD_01087 3e-254 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
KMDGHHAD_01088 5.82e-221 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KMDGHHAD_01089 4.18e-64 yutD - - S - - - protein conserved in bacteria
KMDGHHAD_01090 1.32e-97 yutE - - S - - - Protein of unknown function DUF86
KMDGHHAD_01091 5.87e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KMDGHHAD_01092 5.12e-112 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KMDGHHAD_01093 1.55e-256 yutH - - S - - - Spore coat protein
KMDGHHAD_01094 6.83e-50 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
KMDGHHAD_01095 3.46e-80 yuzD - - S - - - protein conserved in bacteria
KMDGHHAD_01096 4.8e-83 yutM - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
KMDGHHAD_01098 9.63e-56 - - - S - - - Domain of unknown function (DUF5105)
KMDGHHAD_01099 4.36e-100 - - - S - - - response to antibiotic
KMDGHHAD_01100 7.12e-73 - - - S - - - response to antibiotic
KMDGHHAD_01101 1.99e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KMDGHHAD_01102 2.09e-287 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KMDGHHAD_01103 5.14e-62 yuiB - - S - - - Putative membrane protein
KMDGHHAD_01104 3.72e-139 yuiC - - S - - - protein conserved in bacteria
KMDGHHAD_01105 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KMDGHHAD_01107 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
KMDGHHAD_01108 1.02e-279 gerKC - - S ko:K06297 - ko00000 spore germination
KMDGHHAD_01109 5.28e-244 gerKB - - E ko:K06296 - ko00000,ko02000 Spore germination protein
KMDGHHAD_01111 1.38e-82 yuzC - - - - - - -
KMDGHHAD_01112 7.74e-86 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
KMDGHHAD_01113 2.03e-258 yuxJ - - EGP - - - Major facilitator superfamily
KMDGHHAD_01114 3.24e-74 - - - EGP - - - Transmembrane secretion effector
KMDGHHAD_01116 0.0 - 2.7.13.3 - T ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 Histidine kinase
KMDGHHAD_01117 1.06e-198 - 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 chemotaxis
KMDGHHAD_01118 2.67e-272 rsbU 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
KMDGHHAD_01119 2.45e-73 ytpP - - CO - - - Thioredoxin
KMDGHHAD_01120 3.69e-187 ytpQ - - S - - - Belongs to the UPF0354 family
KMDGHHAD_01121 7.55e-142 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMDGHHAD_01122 9.16e-128 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMDGHHAD_01123 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KMDGHHAD_01124 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KMDGHHAD_01125 7.74e-84 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMDGHHAD_01126 1.51e-52 ytxH - - S - - - COG4980 Gas vesicle protein
KMDGHHAD_01127 3.79e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KMDGHHAD_01128 2.41e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KMDGHHAD_01129 9.26e-296 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
KMDGHHAD_01130 8.43e-155 acuB - - S ko:K04767 - ko00000 Acetoin utilization protein AcuB
KMDGHHAD_01131 2e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KMDGHHAD_01132 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMDGHHAD_01133 1.96e-158 - - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Molybdenum ABC transporter
KMDGHHAD_01134 6.28e-133 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
KMDGHHAD_01135 1.19e-170 - 3.6.3.29 - P ko:K02017 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KMDGHHAD_01136 8.82e-241 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KMDGHHAD_01137 1.93e-111 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KMDGHHAD_01138 1.24e-156 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KMDGHHAD_01139 1.31e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
KMDGHHAD_01140 1.55e-114 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KMDGHHAD_01141 1.16e-102 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
KMDGHHAD_01142 1.45e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KMDGHHAD_01143 4.1e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KMDGHHAD_01144 4.95e-247 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMDGHHAD_01145 4.84e-114 yrhD - - S - - - Protein of unknown function (DUF1641)
KMDGHHAD_01146 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KMDGHHAD_01147 3.86e-196 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KMDGHHAD_01149 2.43e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMDGHHAD_01150 3.04e-313 - - - KT - - - Transcriptional regulator
KMDGHHAD_01151 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMDGHHAD_01152 3.44e-237 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KMDGHHAD_01153 5.36e-92 - - - K - - - Helix-turn-helix XRE-family like proteins
KMDGHHAD_01154 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KMDGHHAD_01155 1.35e-156 - - - S - - - PD-(D/E)XK nuclease family transposase
KMDGHHAD_01156 1.88e-89 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 N-4 methylation of cytosine
KMDGHHAD_01157 4.1e-137 - - - S - - - Protein of unknown function DUF262
KMDGHHAD_01158 2.63e-51 - - - - - - - -
KMDGHHAD_01159 1.32e-67 - - - L - - - Transposase
KMDGHHAD_01160 3.82e-95 agaF 2.7.1.191 - G ko:K02744,ko:K02793 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KMDGHHAD_01161 1.01e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
KMDGHHAD_01162 6.56e-182 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
KMDGHHAD_01163 2.81e-106 - 2.7.1.191 - G ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KMDGHHAD_01164 3.04e-171 - 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMDGHHAD_01165 1.28e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
KMDGHHAD_01166 4.47e-126 - - - K - - - Cupin domain
KMDGHHAD_01167 0.0 - 3.5.2.14 - EQ ko:K01473 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
KMDGHHAD_01168 0.0 - 3.5.2.14 - EQ ko:K01474 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit
KMDGHHAD_01169 0.0 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
KMDGHHAD_01170 0.0 - - - K ko:K19505 - ko00000,ko03000 PTS system fructose IIA component
KMDGHHAD_01171 1.26e-95 - 2.7.1.191 - G ko:K02793,ko:K19506 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KMDGHHAD_01172 8.95e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
KMDGHHAD_01173 9.17e-173 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
KMDGHHAD_01174 1.13e-183 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KMDGHHAD_01175 1.96e-253 - - - M - - - SIS domain
KMDGHHAD_01176 3.29e-211 - - - GKT - - - COG3711 Transcriptional antiterminator
KMDGHHAD_01177 9.74e-19 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KMDGHHAD_01178 2.45e-40 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 to PTS system galactitol-specific enzyme IIB component
KMDGHHAD_01179 5.8e-251 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KMDGHHAD_01181 2.65e-76 - 2.7.1.56 - F ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KMDGHHAD_01182 1.93e-109 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
KMDGHHAD_01183 0.0 - - - K - - - COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KMDGHHAD_01184 2.36e-270 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
KMDGHHAD_01185 0.0 - - - EQ - - - Hydantoinase oxoprolinase
KMDGHHAD_01186 1.74e-291 - - - F ko:K10974 - ko00000,ko02000 cytosine purines uracil thiamine allantoin
KMDGHHAD_01187 1.92e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
KMDGHHAD_01188 0.0 apc3 - - EQ - - - Hydantoinase/oxoprolinase
KMDGHHAD_01189 4.48e-231 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KMDGHHAD_01190 1.13e-89 - - - S - - - YjbR
KMDGHHAD_01191 1.52e-68 - - - S - - - Protein of unknown function (DUF1648)
KMDGHHAD_01192 1e-11 - - - S - - - Protein of unknown function (DUF1648)
KMDGHHAD_01193 0.0 - - - L - - - Metallo-beta-lactamase superfamily
KMDGHHAD_01194 1.37e-41 - - - S - - - Protein of unknown function (DUF3006)
KMDGHHAD_01195 1.63e-239 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
KMDGHHAD_01196 3.37e-249 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KMDGHHAD_01197 8.32e-37 - - - K ko:K03481 - ko00000,ko03000 SIS domain
KMDGHHAD_01199 1.58e-54 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KMDGHHAD_01200 4.55e-153 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 dithiol-disulfide isomerase involved in polyketide biosynthesis
KMDGHHAD_01201 1.09e-117 yebE - - S - - - UPF0316 protein
KMDGHHAD_01202 1.37e-41 yebG - - S - - - NETI protein
KMDGHHAD_01203 1.06e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KMDGHHAD_01204 3.47e-279 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KMDGHHAD_01205 8.68e-316 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KMDGHHAD_01206 2.77e-159 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KMDGHHAD_01207 1.09e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMDGHHAD_01208 1.19e-160 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMDGHHAD_01209 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMDGHHAD_01210 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KMDGHHAD_01211 4.06e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KMDGHHAD_01212 6.71e-134 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KMDGHHAD_01213 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KMDGHHAD_01214 2.16e-283 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KMDGHHAD_01215 3.43e-49 - - - S - - - Protein of unknown function (DUF2892)
KMDGHHAD_01216 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
KMDGHHAD_01217 1.86e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
KMDGHHAD_01218 7.4e-71 yerC - - S - - - protein conserved in bacteria
KMDGHHAD_01219 1.57e-167 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KMDGHHAD_01220 3.83e-164 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 AAA domain
KMDGHHAD_01221 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KMDGHHAD_01222 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KMDGHHAD_01223 1.64e-282 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
KMDGHHAD_01224 0.0 aceB 2.3.3.9 - C ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the malate synthase family
KMDGHHAD_01225 4.12e-313 aceA 4.1.3.1 - C ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Isocitrate lyase
KMDGHHAD_01226 2.67e-62 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMDGHHAD_01227 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KMDGHHAD_01228 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMDGHHAD_01230 4.74e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
KMDGHHAD_01231 4.47e-121 - - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
KMDGHHAD_01232 3.72e-132 - - - P ko:K07240 - ko00000,ko02000 Chromate transporter
KMDGHHAD_01233 1.68e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KMDGHHAD_01234 1.52e-34 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
KMDGHHAD_01235 1.43e-47 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
KMDGHHAD_01237 1.71e-206 - - - K - - - Sensory domain found in PocR
KMDGHHAD_01238 1.04e-290 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMDGHHAD_01239 9.6e-269 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KMDGHHAD_01240 8.59e-60 esxA - - S - - - Belongs to the WXG100 family
KMDGHHAD_01241 3.52e-49 yueB - - S - - - domain protein
KMDGHHAD_01242 0.0 yueB - - S - - - domain protein
KMDGHHAD_01243 4.84e-73 - - - Q - - - domain protein
KMDGHHAD_01246 7.21e-236 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_01247 0.0 - - - G ko:K16211 - ko00000,ko02000 Major facilitator Superfamily
KMDGHHAD_01248 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
KMDGHHAD_01249 1.69e-161 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KMDGHHAD_01250 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KMDGHHAD_01251 5.77e-128 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KMDGHHAD_01253 4.42e-57 - - - - - - - -
KMDGHHAD_01254 5.75e-19 - - - S - - - LXG domain of WXG superfamily
KMDGHHAD_01255 9.44e-234 ldhA 1.1.1.28 - CH ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KMDGHHAD_01256 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
KMDGHHAD_01257 3.48e-53 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KMDGHHAD_01258 1.08e-122 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KMDGHHAD_01259 1.09e-221 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_01261 7.56e-62 - - - - - - - -
KMDGHHAD_01262 1.1e-178 - 4.1.1.77 - Q ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 COG3971 2-keto-4-pentenoate hydratase
KMDGHHAD_01263 3.25e-97 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
KMDGHHAD_01264 6.6e-276 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KMDGHHAD_01265 1.63e-158 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
KMDGHHAD_01266 8.85e-97 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
KMDGHHAD_01267 1.92e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KMDGHHAD_01268 2.07e-263 kinA 2.7.13.3 - T ko:K02491,ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_01269 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KMDGHHAD_01270 2.1e-159 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
KMDGHHAD_01271 1.79e-315 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KMDGHHAD_01272 1.05e-93 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
KMDGHHAD_01273 5.44e-85 ylxF - - S - - - MgtE intracellular N domain
KMDGHHAD_01274 0.0 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control
KMDGHHAD_01275 2.39e-139 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
KMDGHHAD_01276 1.51e-94 flg - - N - - - Putative flagellar
KMDGHHAD_01277 5.79e-170 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
KMDGHHAD_01278 1.89e-85 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
KMDGHHAD_01279 7.45e-233 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMDGHHAD_01280 1.17e-249 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMDGHHAD_01281 2.57e-78 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
KMDGHHAD_01282 1.13e-149 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
KMDGHHAD_01283 1.16e-139 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
KMDGHHAD_01284 3.82e-52 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
KMDGHHAD_01285 1.04e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
KMDGHHAD_01286 2.15e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMDGHHAD_01287 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMDGHHAD_01288 7.68e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
KMDGHHAD_01289 2.83e-202 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
KMDGHHAD_01290 2.22e-152 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KMDGHHAD_01291 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
KMDGHHAD_01292 2.9e-90 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KMDGHHAD_01293 1.34e-145 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KMDGHHAD_01294 5.54e-111 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KMDGHHAD_01295 3.94e-174 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMDGHHAD_01296 2.55e-112 ylxL - - - - - - -
KMDGHHAD_01297 1.05e-175 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KMDGHHAD_01298 2.14e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KMDGHHAD_01299 2.67e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KMDGHHAD_01300 3.09e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KMDGHHAD_01301 3.43e-192 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KMDGHHAD_01302 3.27e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KMDGHHAD_01303 7.66e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KMDGHHAD_01304 5.72e-301 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KMDGHHAD_01305 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KMDGHHAD_01306 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMDGHHAD_01307 2.23e-107 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KMDGHHAD_01308 1.72e-285 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KMDGHHAD_01309 2.27e-59 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
KMDGHHAD_01310 3.02e-64 ylxQ - - J - - - ribosomal protein
KMDGHHAD_01311 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KMDGHHAD_01312 4.54e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
KMDGHHAD_01313 6.7e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KMDGHHAD_01314 7.07e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KMDGHHAD_01315 6.65e-234 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KMDGHHAD_01316 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KMDGHHAD_01317 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KMDGHHAD_01318 1.41e-266 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
KMDGHHAD_01319 3.54e-296 mlpA - - S - - - Belongs to the peptidase M16 family
KMDGHHAD_01320 2.52e-51 ymxH - - S - - - YlmC YmxH family
KMDGHHAD_01321 4.2e-241 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
KMDGHHAD_01322 1.46e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KMDGHHAD_01323 4.2e-242 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KMDGHHAD_01324 7.04e-288 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KMDGHHAD_01325 1.35e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMDGHHAD_01326 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMDGHHAD_01327 1.18e-169 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
KMDGHHAD_01328 6.67e-47 - - - S - - - YlzJ-like protein
KMDGHHAD_01329 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KMDGHHAD_01330 1.43e-252 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KMDGHHAD_01331 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_01332 1.07e-239 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMDGHHAD_01333 4.58e-220 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMDGHHAD_01334 1.25e-302 albE - - S - - - Peptidase M16
KMDGHHAD_01335 1.74e-311 ymfH - - S - - - zinc protease
KMDGHHAD_01336 2.69e-186 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KMDGHHAD_01337 2.25e-54 ymfJ - - S - - - Protein of unknown function (DUF3243)
KMDGHHAD_01338 5.9e-188 ymfK - - S - - - Protein of unknown function (DUF3388)
KMDGHHAD_01339 7.86e-186 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
KMDGHHAD_01340 7.3e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMDGHHAD_01341 7.64e-290 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KMDGHHAD_01342 1.53e-243 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KMDGHHAD_01343 1.41e-304 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KMDGHHAD_01344 1.02e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
KMDGHHAD_01345 1.21e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
KMDGHHAD_01346 1.04e-217 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KMDGHHAD_01347 1.97e-316 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
KMDGHHAD_01348 0.0 - - - E ko:K14052 - ko00000,ko02000 Amino acid permease
KMDGHHAD_01349 0.0 - - - KT - - - COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KMDGHHAD_01350 0.0 - 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMDGHHAD_01351 0.0 - 2.6.1.82 - E ko:K09251 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMDGHHAD_01352 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KMDGHHAD_01353 1.8e-84 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KMDGHHAD_01354 4.31e-128 - - - S ko:K06328 - ko00000 Outer spore coat protein E (CotE)
KMDGHHAD_01355 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KMDGHHAD_01356 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KMDGHHAD_01357 2.41e-50 yhjA - - S - - - Excalibur calcium-binding domain
KMDGHHAD_01358 3.27e-47 - - - S - - - protein secretion by the type IV secretion system
KMDGHHAD_01360 9e-08 - - - - - - - -
KMDGHHAD_01361 3.22e-246 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KMDGHHAD_01362 1.4e-48 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KMDGHHAD_01364 4.44e-224 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
KMDGHHAD_01365 3.13e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KMDGHHAD_01366 7.1e-313 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KMDGHHAD_01367 2.45e-214 ypcP - - L - - - 5'3' exonuclease
KMDGHHAD_01369 1.59e-37 ypeQ - - S - - - Zinc-finger
KMDGHHAD_01370 4.69e-43 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KMDGHHAD_01371 3.17e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KMDGHHAD_01372 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KMDGHHAD_01373 1.86e-109 - - - - - - - -
KMDGHHAD_01374 7.49e-154 ypgQ - - S ko:K06950 - ko00000 phosphohydrolase
KMDGHHAD_01375 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMDGHHAD_01376 5.73e-221 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
KMDGHHAD_01377 2.03e-96 yphP - - S - - - Belongs to the UPF0403 family
KMDGHHAD_01378 9.63e-136 ypjP - - S - - - YpjP-like protein
KMDGHHAD_01379 3.07e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMDGHHAD_01380 2.38e-119 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMDGHHAD_01381 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KMDGHHAD_01382 9.68e-179 - - - E - - - COG2755 Lysophospholipase L1 and related esterases
KMDGHHAD_01383 1.95e-127 ypmS - - S - - - protein conserved in bacteria
KMDGHHAD_01384 0.0 rsmF - - J - - - RNA-binding PUA-like domain of methyltransferase RsmF
KMDGHHAD_01385 4.5e-134 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMDGHHAD_01386 5.45e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KMDGHHAD_01387 1.62e-28 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMDGHHAD_01388 1.08e-308 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 CHASE3 domain
KMDGHHAD_01389 2.13e-48 yozE - - S - - - Belongs to the UPF0346 family
KMDGHHAD_01390 1.11e-149 yodN - - - - - - -
KMDGHHAD_01391 1.12e-33 yozD - - S - - - YozD-like protein
KMDGHHAD_01393 1.34e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KMDGHHAD_01394 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KMDGHHAD_01395 1.42e-87 ypoP - - K - - - transcriptional
KMDGHHAD_01396 5.42e-150 ykwD - - J - - - protein with SCP PR1 domains
KMDGHHAD_01397 0.0 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KMDGHHAD_01399 5.31e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KMDGHHAD_01400 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
KMDGHHAD_01401 5.34e-182 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KMDGHHAD_01402 1.48e-137 pap2c 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KMDGHHAD_01404 0.0 yfnI 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KMDGHHAD_01405 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KMDGHHAD_01406 8.45e-283 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_01407 2.21e-156 csrR - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMDGHHAD_01408 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_01409 3.9e-105 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
KMDGHHAD_01410 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KMDGHHAD_01411 4.23e-269 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KMDGHHAD_01412 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KMDGHHAD_01413 8.87e-120 rok - - S - - - Repressor of ComK
KMDGHHAD_01414 9.19e-153 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMDGHHAD_01416 4.34e-41 - - - S - - - Protein of unknown function, DUF600
KMDGHHAD_01417 5.44e-47 yxiG - - - - - - -
KMDGHHAD_01418 1.34e-51 - - - S - - - Protein of unknown function, DUF600
KMDGHHAD_01419 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
KMDGHHAD_01420 9.66e-132 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 PFAM restriction modification system DNA specificity domain
KMDGHHAD_01421 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KMDGHHAD_01422 0.0 - - - V ko:K07452 - ko00000,ko01000,ko02048 AAA domain (dynein-related subfamily)
KMDGHHAD_01423 1.89e-252 - - - V ko:K19147 - ko00000,ko02048 McrBC 5-methylcytosine restriction system component
KMDGHHAD_01425 5.86e-33 - - - - - - - -
KMDGHHAD_01426 4.11e-71 - - - M - - - SIS domain
KMDGHHAD_01427 1.58e-207 fda 4.1.2.13 - G ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 Belongs to the class I fructose-bisphosphate aldolase family
KMDGHHAD_01428 3.89e-265 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KMDGHHAD_01429 3.24e-156 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 nitrate reductase, gamma subunit
KMDGHHAD_01430 2.17e-128 - - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
KMDGHHAD_01431 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
KMDGHHAD_01432 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMDGHHAD_01433 3.01e-58 - - - - - - - -
KMDGHHAD_01434 3.42e-69 - - - - - - - -
KMDGHHAD_01435 9.11e-92 - - - S - - - Hemerythrin HHE cation binding domain
KMDGHHAD_01436 1.68e-167 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KMDGHHAD_01437 9.55e-255 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KMDGHHAD_01438 4.09e-145 ycfA - - K - - - Transcriptional regulator
KMDGHHAD_01439 0.0 lysP - - E ko:K11733 - ko00000,ko02000 amino acid
KMDGHHAD_01440 1.88e-307 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KMDGHHAD_01441 5.61e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
KMDGHHAD_01443 3.66e-139 - 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Bacterial fructose-1,6-bisphosphatase, glpX-encoded
KMDGHHAD_01444 3.67e-125 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KMDGHHAD_01445 1.07e-80 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
KMDGHHAD_01447 5.65e-172 - - - G - - - Xylose isomerase-like TIM barrel
KMDGHHAD_01449 4.31e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
KMDGHHAD_01450 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KMDGHHAD_01451 1.84e-316 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KMDGHHAD_01452 9.21e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KMDGHHAD_01453 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KMDGHHAD_01454 9.26e-201 yybS - - S - - - membrane
KMDGHHAD_01455 7.33e-50 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KMDGHHAD_01456 2.87e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KMDGHHAD_01457 3.01e-63 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KMDGHHAD_01458 3.83e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KMDGHHAD_01459 3.45e-284 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMDGHHAD_01460 4.32e-148 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KMDGHHAD_01461 2.86e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KMDGHHAD_01462 1.51e-260 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KMDGHHAD_01463 3.73e-44 yyzM - - S - - - protein conserved in bacteria
KMDGHHAD_01464 2.94e-208 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
KMDGHHAD_01465 1.52e-144 yyaC - - S - - - Sporulation protein YyaC
KMDGHHAD_01466 1.58e-150 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KMDGHHAD_01467 3.25e-192 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KMDGHHAD_01468 6.81e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
KMDGHHAD_01469 2.69e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KMDGHHAD_01470 3.04e-173 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KMDGHHAD_01471 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KMDGHHAD_01472 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KMDGHHAD_01473 2.94e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
KMDGHHAD_01474 5.78e-174 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMDGHHAD_01475 7.56e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KMDGHHAD_01476 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KMDGHHAD_01477 9.58e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KMDGHHAD_01478 2.41e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KMDGHHAD_01479 1.77e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMDGHHAD_01480 9.35e-16 yaaB - - S - - - Domain of unknown function (DUF370)
KMDGHHAD_01481 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMDGHHAD_01482 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMDGHHAD_01483 4.81e-252 M1-161 - - T - - - HD domain
KMDGHHAD_01484 1.06e-67 - - - S - - - ABC-2 family transporter protein
KMDGHHAD_01485 1.39e-46 - - - S - - - ABC-2 family transporter protein
KMDGHHAD_01486 9.57e-59 - - - S - - - YfzA-like protein
KMDGHHAD_01487 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KMDGHHAD_01488 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
KMDGHHAD_01489 1.52e-212 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_01490 1.13e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_01491 2.95e-23 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
KMDGHHAD_01492 4.1e-49 ygaB - - S - - - YgaB-like protein
KMDGHHAD_01493 5.7e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KMDGHHAD_01494 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
KMDGHHAD_01495 4.39e-270 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
KMDGHHAD_01496 1.74e-196 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KMDGHHAD_01497 0.0 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMDGHHAD_01498 5.92e-201 yleF - - K - - - transcriptional
KMDGHHAD_01499 5.71e-241 ygaE - - S - - - Membrane
KMDGHHAD_01500 1.41e-53 yqhV - - S - - - Protein of unknown function (DUF2619)
KMDGHHAD_01501 2.57e-80 - - - - - - - -
KMDGHHAD_01502 7.1e-292 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_01503 7.17e-146 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMDGHHAD_01504 1.5e-185 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KMDGHHAD_01505 5.87e-182 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMDGHHAD_01506 4.73e-241 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMDGHHAD_01507 3.19e-315 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KMDGHHAD_01508 1.04e-86 - - - P ko:K08713 - ko00000,ko02000 Ion transport
KMDGHHAD_01509 3.81e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
KMDGHHAD_01510 2.85e-107 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KMDGHHAD_01511 1.16e-210 - - - K - - - LysR substrate binding domain
KMDGHHAD_01512 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KMDGHHAD_01513 3.99e-179 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KMDGHHAD_01514 3.29e-75 ygzB - - S - - - UPF0295 protein
KMDGHHAD_01515 1.07e-208 ygxA - - S - - - Nucleotidyltransferase-like
KMDGHHAD_01516 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KMDGHHAD_01517 0.0 - 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_01518 1.94e-267 - 2.3.1.16, 2.3.1.9 - I ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KMDGHHAD_01519 2.99e-174 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KMDGHHAD_01520 1.65e-35 sspH - - S ko:K06425 - ko00000 small acid-soluble spore protein
KMDGHHAD_01521 2.03e-135 ymdB - - S - - - Appr-1'-p processing enzyme
KMDGHHAD_01523 1.32e-219 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
KMDGHHAD_01524 9.27e-75 - - - I - - - SCP-2 sterol transfer family
KMDGHHAD_01525 2.64e-246 - - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KMDGHHAD_01526 9.58e-245 - - - M ko:K05802,ko:K22051 - ko00000,ko02000 Mechanosensitive ion channel
KMDGHHAD_01527 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
KMDGHHAD_01528 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMDGHHAD_01529 6.89e-278 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMDGHHAD_01530 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMDGHHAD_01531 6.98e-241 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMDGHHAD_01532 3.5e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
KMDGHHAD_01533 0.0 dapE - - E - - - Peptidase dimerisation domain
KMDGHHAD_01534 4.29e-173 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
KMDGHHAD_01535 1.31e-141 - - - - - - - -
KMDGHHAD_01536 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KMDGHHAD_01537 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMDGHHAD_01538 1.78e-164 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
KMDGHHAD_01539 7.71e-183 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
KMDGHHAD_01540 1.87e-97 - - - S ko:K06991 - ko00000 Glyoxalase bleomycin resistance protein dioxygenase
KMDGHHAD_01541 2.94e-237 - - - P ko:K02051,ko:K15598 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KMDGHHAD_01542 6.85e-178 ssuC - - P ko:K15599 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
KMDGHHAD_01543 6.19e-248 yfiS - - EGP - - - Major facilitator superfamily
KMDGHHAD_01544 4.18e-155 - - - K - - - Bacterial regulatory proteins, tetR family
KMDGHHAD_01545 1.43e-109 - - - S - - - Psort location CytoplasmicMembrane, score
KMDGHHAD_01546 7.8e-153 - - - S - - - Psort location CytoplasmicMembrane, score
KMDGHHAD_01548 9.48e-108 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KMDGHHAD_01550 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KMDGHHAD_01551 0.0 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KMDGHHAD_01552 1.03e-21 csbD - - S - - - Belongs to the UPF0337 (CsbD) family
KMDGHHAD_01553 1.62e-115 - - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 ComK protein
KMDGHHAD_01554 1.72e-136 - 2.7.7.6 - K ko:K00960 - ko00000,ko01000 Belongs to the sigma-70 factor family. ECF subfamily
KMDGHHAD_01555 2.07e-196 - - - E - - - lipolytic protein G-D-S-L family
KMDGHHAD_01556 5.91e-154 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
KMDGHHAD_01557 6.23e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KMDGHHAD_01558 8.34e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
KMDGHHAD_01559 1.73e-191 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KMDGHHAD_01560 3.09e-116 cpsE - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
KMDGHHAD_01561 7.34e-43 - - - S - - - Membrane protein involved in the export of O-antigen and teichoic acid
KMDGHHAD_01562 2.11e-45 - - - M - - - Bacterial transferase hexapeptide (six repeats)
KMDGHHAD_01564 8.48e-44 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
KMDGHHAD_01565 2.49e-33 - - - S - - - Glycosyltransferase family 28 C-terminal domain
KMDGHHAD_01566 8.15e-42 - - - M - - - transferase activity, transferring glycosyl groups
KMDGHHAD_01567 3.09e-240 - 2.7.7.13 - G ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 mannose-1-phosphate guanylyltransferase
KMDGHHAD_01568 1.14e-295 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMDGHHAD_01569 1.64e-114 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMDGHHAD_01570 9.41e-136 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMDGHHAD_01571 5.48e-215 - - - S ko:K07459 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
KMDGHHAD_01572 5.31e-146 xylR - - GK - - - Transcriptional regulator
KMDGHHAD_01573 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
KMDGHHAD_01574 1.71e-253 xylP - - G ko:K03292 - ko00000 MFS/sugar transport protein
KMDGHHAD_01575 4.72e-19 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification
KMDGHHAD_01577 3.34e-120 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
KMDGHHAD_01578 6.6e-124 - - - I - - - Domain of unknown function (DUF4430)
KMDGHHAD_01579 2.14e-290 - - - M - - - FFAT motif binding
KMDGHHAD_01580 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
KMDGHHAD_01581 2.13e-276 hipO3 - - S ko:K21613 - ko00000,ko01000,ko01002 amidohydrolase
KMDGHHAD_01582 2.89e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KMDGHHAD_01583 1.13e-145 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KMDGHHAD_01584 8.99e-167 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMDGHHAD_01585 7.57e-103 ymaD - - O - - - redox protein, regulator of disulfide bond formation
KMDGHHAD_01586 1.89e-274 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_01588 1.56e-169 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
KMDGHHAD_01589 4.13e-230 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
KMDGHHAD_01590 3.94e-173 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
KMDGHHAD_01591 9.65e-152 - - - S - - - Protein of unknown function (DUF969)
KMDGHHAD_01592 2.83e-213 - - - S - - - Protein of unknown function (DUF979)
KMDGHHAD_01593 3.17e-150 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KMDGHHAD_01594 2.37e-290 pbuO_1 - - S ko:K06901 - ko00000,ko02000 permease
KMDGHHAD_01595 6.29e-272 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMDGHHAD_01596 4.14e-164 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KMDGHHAD_01597 4.09e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMDGHHAD_01598 8.61e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KMDGHHAD_01599 1.03e-300 deoA 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
KMDGHHAD_01600 1.39e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMDGHHAD_01601 1.74e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KMDGHHAD_01602 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMDGHHAD_01603 2.4e-194 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KMDGHHAD_01604 3.02e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
KMDGHHAD_01605 9.48e-188 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
KMDGHHAD_01606 1.26e-105 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KMDGHHAD_01607 1.59e-78 ywdK - - S - - - small membrane protein
KMDGHHAD_01608 5.79e-52 - - - S - - - Family of unknown function (DUF5327)
KMDGHHAD_01609 1.11e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KMDGHHAD_01610 5.51e-73 - - - S - - - Heat induced stress protein YflT
KMDGHHAD_01611 3.71e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
KMDGHHAD_01612 1.74e-26 - - - S - - - Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
KMDGHHAD_01613 0.0 - - - - - - - -
KMDGHHAD_01614 7.25e-47 - - - S - - - Stage II sporulation protein M
KMDGHHAD_01615 3.74e-156 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KMDGHHAD_01618 6.72e-131 - - - S - - - ABC-2 family transporter protein
KMDGHHAD_01619 3.12e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KMDGHHAD_01621 1.06e-262 - - - - - - - -
KMDGHHAD_01622 9.44e-194 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KMDGHHAD_01623 5.49e-82 yojF - - S - - - Protein of unknown function (DUF1806)
KMDGHHAD_01624 2.42e-169 bshB2 - - S ko:K22135 - ko00000,ko01000 deacetylase
KMDGHHAD_01625 1.96e-223 ycsE - - S - - - hydrolases of the HAD superfamily
KMDGHHAD_01626 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMDGHHAD_01627 7.04e-288 phoA 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KMDGHHAD_01628 4.69e-199 murR - - K - - - Transcriptional regulator
KMDGHHAD_01629 1.18e-195 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KMDGHHAD_01630 1.73e-19 - - - - - - - -
KMDGHHAD_01631 7.86e-97 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KMDGHHAD_01633 1.43e-152 ywbG - - M - - - effector of murein hydrolase
KMDGHHAD_01634 4.35e-77 ywbH - - S ko:K06518 - ko00000,ko02000 LrgA family
KMDGHHAD_01635 3.16e-233 ywbI - - K - - - Transcriptional regulator
KMDGHHAD_01636 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KMDGHHAD_01637 2.33e-206 - - - S - - - Protein of unknown function (DUF1646)
KMDGHHAD_01639 5.25e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
KMDGHHAD_01640 1.07e-159 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KMDGHHAD_01641 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KMDGHHAD_01642 1.65e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMDGHHAD_01645 1.13e-81 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
KMDGHHAD_01646 3.92e-110 yppG - - S - - - YppG-like protein
KMDGHHAD_01647 3.62e-100 hspc4-1 - - O - - - Belongs to the small heat shock protein (HSP20) family
KMDGHHAD_01648 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KMDGHHAD_01649 0.0 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
KMDGHHAD_01650 2.98e-62 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
KMDGHHAD_01651 1.56e-132 ypsA - - S - - - Belongs to the UPF0398 family
KMDGHHAD_01652 2.07e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KMDGHHAD_01653 3.3e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KMDGHHAD_01654 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KMDGHHAD_01655 2.74e-132 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KMDGHHAD_01656 5.86e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
KMDGHHAD_01657 4.41e-169 - - - O - - - prohibitin homologues
KMDGHHAD_01658 3.54e-47 - - - - - - - -
KMDGHHAD_01659 0.0 ypbR - - S - - - Dynamin family
KMDGHHAD_01660 1.01e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
KMDGHHAD_01661 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KMDGHHAD_01662 1.94e-173 - - - L - - - Arm DNA-binding domain
KMDGHHAD_01663 4.96e-58 - - - E - - - IrrE N-terminal-like domain
KMDGHHAD_01665 0.0 - - - L - - - Type III restriction protein, res subunit
KMDGHHAD_01666 5.34e-52 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 RNase_H superfamily
KMDGHHAD_01667 5.8e-94 - - - L - - - PFAM BRCA1 C Terminus (BRCT) domain
KMDGHHAD_01668 3.79e-121 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KMDGHHAD_01669 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
KMDGHHAD_01670 1.53e-139 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
KMDGHHAD_01671 2.37e-176 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMDGHHAD_01672 8.05e-106 rsbW 2.7.11.1 - T ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KMDGHHAD_01673 5.11e-80 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
KMDGHHAD_01674 1.65e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
KMDGHHAD_01675 5.15e-91 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KMDGHHAD_01676 3.41e-73 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
KMDGHHAD_01677 1.24e-195 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
KMDGHHAD_01678 1.25e-74 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KMDGHHAD_01679 1.47e-55 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KMDGHHAD_01680 8.36e-278 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMDGHHAD_01681 1.42e-244 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
KMDGHHAD_01682 5.48e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KMDGHHAD_01683 3.46e-137 ydcA 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KMDGHHAD_01684 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KMDGHHAD_01685 7.99e-79 - - - - - - - -
KMDGHHAD_01686 3.56e-138 ycgF - - E - - - Lysine exporter protein LysE YggA
KMDGHHAD_01687 6.6e-158 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KMDGHHAD_01688 2.04e-227 yvdE - - K - - - Transcriptional regulator
KMDGHHAD_01689 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMDGHHAD_01690 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
KMDGHHAD_01691 1.37e-310 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KMDGHHAD_01692 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KMDGHHAD_01693 1.19e-197 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KMDGHHAD_01694 6.56e-189 malA - - S - - - Protein of unknown function (DUF1189)
KMDGHHAD_01695 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
KMDGHHAD_01696 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMDGHHAD_01697 2.61e-123 ywhH - - S - - - Aminoacyl-tRNA editing domain
KMDGHHAD_01698 2.5e-139 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
KMDGHHAD_01699 3.81e-171 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
KMDGHHAD_01700 8.69e-180 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KMDGHHAD_01701 2.61e-180 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KMDGHHAD_01702 0.0 yobO - - M - - - Pectate lyase superfamily protein
KMDGHHAD_01703 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMDGHHAD_01704 1.43e-251 - - - S - - - Phosphotransferase enzyme family
KMDGHHAD_01705 5.34e-89 - - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KMDGHHAD_01707 2.1e-123 - - - K - - - Transcriptional regulator
KMDGHHAD_01708 5.9e-91 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_01709 2.17e-220 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_01710 2.89e-176 - 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_01711 7.27e-306 bbsG 1.3.8.7 - I ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 COG1960 Acyl-CoA dehydrogenases
KMDGHHAD_01712 9.24e-246 - - - T ko:K17763 - ko00000,ko03021 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
KMDGHHAD_01713 6.56e-164 yeeN - - K - - - transcriptional regulatory protein
KMDGHHAD_01714 1.04e-136 - - - - - - - -
KMDGHHAD_01715 2.4e-129 - - - - - - - -
KMDGHHAD_01716 1.56e-144 - - - - - - - -
KMDGHHAD_01717 2.28e-248 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KMDGHHAD_01718 2.06e-192 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMDGHHAD_01719 2.79e-226 fhuD9 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KMDGHHAD_01720 1.44e-233 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMDGHHAD_01721 4.95e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMDGHHAD_01722 2.2e-177 yfcA - - S ko:K07090 - ko00000 membrane transporter protein
KMDGHHAD_01723 3.62e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
KMDGHHAD_01724 1.17e-62 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
KMDGHHAD_01725 7.22e-148 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMDGHHAD_01726 1.8e-120 - - - Q - - - Thioesterase superfamily
KMDGHHAD_01727 5.48e-37 - - - K - - - transcriptional
KMDGHHAD_01728 2.28e-05 - - - K - - - XRE family transcriptional regulator
KMDGHHAD_01729 2.19e-74 - - - - - - - -
KMDGHHAD_01730 1.79e-39 - - - - - - - -
KMDGHHAD_01735 1.78e-102 - - - L - - - Replication initiation and membrane attachment
KMDGHHAD_01736 2.03e-48 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KMDGHHAD_01742 2.76e-70 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
KMDGHHAD_01743 1.72e-68 - - - M - - - UDP-N-acetyl-D-mannosamine dehydrogenase activity
KMDGHHAD_01744 1.03e-90 - - - L - - - Phage integrase family
KMDGHHAD_01745 1.37e-24 - - - - - - - -
KMDGHHAD_01746 3.92e-23 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH nucleases
KMDGHHAD_01747 1.32e-28 - - - - - - - -
KMDGHHAD_01748 1.98e-315 - - - S - - - Terminase
KMDGHHAD_01749 1.48e-167 - - - S - - - TIGRFAM phage portal protein, HK97 family
KMDGHHAD_01750 2.16e-87 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
KMDGHHAD_01751 1.98e-107 - - - S - - - Phage capsid family
KMDGHHAD_01752 4.32e-31 - - - S - - - Phage gp6-like head-tail connector protein
KMDGHHAD_01753 1.05e-28 - - - S - - - Phage head-tail joining protein
KMDGHHAD_01754 7.11e-16 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KMDGHHAD_01756 4.55e-36 - - - S - - - Phage tail tube protein
KMDGHHAD_01758 9.9e-265 - - - D - - - Phage tail tape measure protein
KMDGHHAD_01759 4.79e-42 - - - S - - - Phage tail protein
KMDGHHAD_01760 1.07e-87 - - - S - - - Prophage endopeptidase tail
KMDGHHAD_01761 4.83e-115 - - - S - - - Calcineurin-like phosphoesterase
KMDGHHAD_01764 5.81e-15 - - - - - - - -
KMDGHHAD_01765 8.5e-19 - - - - - - - -
KMDGHHAD_01766 1.88e-19 - - - S - - - Haemolysin XhlA
KMDGHHAD_01767 5.75e-31 - - - S - - - SPP1 phage holin
KMDGHHAD_01768 1.26e-75 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 hmm pf01520
KMDGHHAD_01770 3.86e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KMDGHHAD_01771 1.94e-76 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KMDGHHAD_01772 3.69e-150 yneB - - L - - - resolvase
KMDGHHAD_01773 5.7e-44 ynzC - - S - - - UPF0291 protein
KMDGHHAD_01774 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KMDGHHAD_01775 2.67e-101 yneE - - S - - - Sporulation inhibitor of replication protein sirA
KMDGHHAD_01776 1.25e-38 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KMDGHHAD_01777 1.01e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
KMDGHHAD_01778 1.96e-77 yneI - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
KMDGHHAD_01779 1.09e-100 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
KMDGHHAD_01780 9.17e-100 yneK - - S - - - Protein of unknown function (DUF2621)
KMDGHHAD_01781 1.36e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMDGHHAD_01782 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KMDGHHAD_01783 2.2e-224 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KMDGHHAD_01785 2.54e-42 - - - K ko:K03704 - ko00000,ko03000 Cold shock
KMDGHHAD_01786 1.02e-112 - - - - - - - -
KMDGHHAD_01787 2.42e-197 yjqC - - P ko:K07217 - ko00000 Catalase
KMDGHHAD_01788 3.71e-105 - - - - - - - -
KMDGHHAD_01790 6.35e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KMDGHHAD_01791 1.11e-299 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KMDGHHAD_01792 8.33e-183 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KMDGHHAD_01793 4.74e-287 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KMDGHHAD_01794 1.12e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KMDGHHAD_01795 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
KMDGHHAD_01796 1.89e-227 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KMDGHHAD_01797 2.21e-295 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KMDGHHAD_01798 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KMDGHHAD_01799 4.4e-290 - 2.6.1.83 - E ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KMDGHHAD_01800 1.97e-63 - - - P ko:K04758 - ko00000,ko02000 COG1918 Fe2 transport system protein A
KMDGHHAD_01801 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
KMDGHHAD_01802 3.77e-32 - - - S - - - Virus attachment protein p12 family
KMDGHHAD_01803 3.93e-140 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMDGHHAD_01804 2.53e-67 tnrA - - K - - - transcriptional
KMDGHHAD_01805 2.23e-167 yvpB - - NU - - - protein conserved in bacteria
KMDGHHAD_01806 8.07e-164 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KMDGHHAD_01807 4.44e-295 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
KMDGHHAD_01808 2.59e-277 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KMDGHHAD_01809 1.52e-93 yjlC - - S - - - Protein of unknown function (DUF1641)
KMDGHHAD_01810 4.84e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMDGHHAD_01811 7.11e-293 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KMDGHHAD_01812 4.41e-247 - - - S ko:K07089 - ko00000 Predicted permease
KMDGHHAD_01813 3.42e-175 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
KMDGHHAD_01814 4.42e-249 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
KMDGHHAD_01815 1.97e-256 selU - - S ko:K06917 - ko00000,ko01000,ko03016 tRNA 2-selenouridine synthase
KMDGHHAD_01817 3.69e-282 dld 1.1.2.4 - C ko:K00102 ko00620,map00620 ko00000,ko00001,ko01000 Glycolate oxidase subunit
KMDGHHAD_01818 1.58e-34 dld 1.1.2.4 - C ko:K00102 ko00620,map00620 ko00000,ko00001,ko01000 Glycolate oxidase subunit
KMDGHHAD_01819 1.29e-198 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_01820 1.59e-104 - - - I - - - N-terminal half of MaoC dehydratase
KMDGHHAD_01821 3.34e-92 - - - I - - - MaoC like domain
KMDGHHAD_01822 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMDGHHAD_01823 5.09e-51 - - - S - - - Protein of unknown function (DUF1450)
KMDGHHAD_01824 1.52e-114 - - - S - - - Protein of unknown function (DUF1189)
KMDGHHAD_01825 6.74e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KMDGHHAD_01826 1.87e-74 - - - - - - - -
KMDGHHAD_01827 6.27e-219 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_01828 3.76e-217 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KMDGHHAD_01829 2.41e-106 - - - V - - - VanZ like family
KMDGHHAD_01830 1.03e-100 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
KMDGHHAD_01831 5.39e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KMDGHHAD_01832 3.46e-155 XK27_06885 - - L - - - COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KMDGHHAD_01834 3.08e-123 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
KMDGHHAD_01835 5.98e-116 - - - Q - - - protein disulfide oxidoreductase activity
KMDGHHAD_01836 1.19e-31 - - - S - - - YpzG-like protein
KMDGHHAD_01838 5.37e-250 - - - G ko:K07190 ko04020,ko04910,ko04922,map04020,map04910,map04922 ko00000,ko00001 Glycosyl hydrolases family 15
KMDGHHAD_01839 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KMDGHHAD_01840 2.8e-277 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KMDGHHAD_01841 2.39e-254 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
KMDGHHAD_01842 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KMDGHHAD_01843 5.92e-201 - 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KMDGHHAD_01844 1.99e-189 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KMDGHHAD_01845 1.28e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
KMDGHHAD_01846 3.14e-275 - - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_01847 5.19e-170 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_01848 1.9e-232 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KMDGHHAD_01849 3.38e-104 - - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMDGHHAD_01850 1.83e-79 - - - - - - - -
KMDGHHAD_01851 2.03e-125 yozB - - S ko:K08976 - ko00000 membrane
KMDGHHAD_01852 9.84e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KMDGHHAD_01853 2.31e-46 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KMDGHHAD_01854 2.39e-255 - - - P - - - FAD-NAD(P)-binding
KMDGHHAD_01855 9.28e-46 - 4.1.1.97 - S ko:K13485 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 OHCU decarboxylase
KMDGHHAD_01856 5.5e-193 - - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
KMDGHHAD_01857 4.31e-192 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
KMDGHHAD_01858 3.21e-179 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KMDGHHAD_01859 9.11e-243 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KMDGHHAD_01860 0.0 - 6.2.1.16 - I ko:K01907 ko00280,ko00650,map00280,map00650 ko00000,ko00001,ko01000,ko01004 AMP-dependent synthetase
KMDGHHAD_01861 5.27e-32 - - - - - - - -
KMDGHHAD_01862 0.0 - - - L ko:K07459 - ko00000 AAA ATPase domain
KMDGHHAD_01863 0.0 - 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction
KMDGHHAD_01864 2.56e-316 mod 2.1.1.72, 3.1.21.5 - L ko:K01156,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
KMDGHHAD_01865 8.9e-51 - - - K - - - Cro/C1-type HTH DNA-binding domain
KMDGHHAD_01866 0.0 - - - L ko:K06919 - ko00000 Phage plasmid primase, P4 family
KMDGHHAD_01867 1.78e-174 - - - S - - - Phage capsid family
KMDGHHAD_01868 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
KMDGHHAD_01869 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Papain family cysteine protease
KMDGHHAD_01870 2.62e-268 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
KMDGHHAD_01871 3.78e-218 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_01872 2.18e-169 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_01873 2.76e-216 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
KMDGHHAD_01881 9.11e-182 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
KMDGHHAD_01882 4.73e-123 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
KMDGHHAD_01883 4.83e-98 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMDGHHAD_01885 2.02e-52 spoVIF - - S - - - Stage VI sporulation protein F
KMDGHHAD_01886 6.11e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KMDGHHAD_01887 9.08e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KMDGHHAD_01888 2.57e-222 yhbB - - S - - - Putative amidase domain
KMDGHHAD_01889 6.6e-115 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KMDGHHAD_01890 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
KMDGHHAD_01891 3.3e-282 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
KMDGHHAD_01893 1.74e-135 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KMDGHHAD_01894 3.14e-229 pit - - P ko:K03306 - ko00000 phosphate transporter
KMDGHHAD_01895 5.31e-149 ykaA - - P ko:K07220 - ko00000 Protein of unknown function DUF47
KMDGHHAD_01896 5.77e-118 yhcU - - S - - - Family of unknown function (DUF5365)
KMDGHHAD_01897 1.43e-110 bdbA - - CO - - - Thioredoxin
KMDGHHAD_01898 8.01e-97 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
KMDGHHAD_01899 4.17e-173 - - - E - - - GDSL-like Lipase/Acylhydrolase
KMDGHHAD_01900 8.08e-234 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
KMDGHHAD_01901 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
KMDGHHAD_01903 7.12e-61 yhdB - - S - - - YhdB-like protein
KMDGHHAD_01904 5.29e-238 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
KMDGHHAD_01905 2.4e-168 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
KMDGHHAD_01906 4.48e-206 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMDGHHAD_01907 7.38e-225 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMDGHHAD_01908 1.78e-241 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_01909 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMDGHHAD_01910 1.01e-228 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMDGHHAD_01911 1.79e-242 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_01913 2.54e-112 nhaX - - T - - - Universal stress protein
KMDGHHAD_01914 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KMDGHHAD_01915 5.83e-251 M1-600 - - T - - - Putative diguanylate phosphodiesterase
KMDGHHAD_01916 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMDGHHAD_01917 4.97e-138 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KMDGHHAD_01918 3.17e-184 - - - G - - - Polysaccharide deacetylase
KMDGHHAD_01919 6.85e-313 ugtP5 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Monogalactosyldiacylglycerol (MGDG) synthase
KMDGHHAD_01920 2.15e-184 - - - - - - - -
KMDGHHAD_01921 1.41e-114 - - - S - - - Putative zinc-finger
KMDGHHAD_01922 1.34e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KMDGHHAD_01923 7.84e-286 ykoN 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KMDGHHAD_01924 0.0 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
KMDGHHAD_01925 0.0 - - - NU ko:K02650 ko02020,map02020 ko00000,ko00001,ko02035,ko02044 cell adhesion
KMDGHHAD_01926 2.26e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KMDGHHAD_01927 1.82e-228 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KMDGHHAD_01928 6.51e-214 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KMDGHHAD_01929 1.01e-181 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_01930 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
KMDGHHAD_01931 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
KMDGHHAD_01932 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KMDGHHAD_01933 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
KMDGHHAD_01934 1.04e-244 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
KMDGHHAD_01935 5.43e-156 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
KMDGHHAD_01936 2.29e-177 - - - K - - - helix_turn_helix isocitrate lyase regulation
KMDGHHAD_01937 6.14e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
KMDGHHAD_01938 1.81e-103 - - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KMDGHHAD_01939 7.08e-292 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMDGHHAD_01940 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KMDGHHAD_01941 1.32e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KMDGHHAD_01942 1.86e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMDGHHAD_01943 3.82e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KMDGHHAD_01944 4.05e-306 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMDGHHAD_01945 1.17e-73 yqiX - - S - - - YolD-like protein
KMDGHHAD_01946 1.82e-311 yaaH_2 - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KMDGHHAD_01947 2.21e-225 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KMDGHHAD_01948 1.5e-276 yaaN - - P - - - Belongs to the TelA family
KMDGHHAD_01949 8.3e-142 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KMDGHHAD_01951 1.86e-05 - - - S - - - Protein of unknown function (DUF3886)
KMDGHHAD_01952 1.52e-210 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KMDGHHAD_01953 4.88e-08 - - - S - - - Protein of unknown function (DUF3936)
KMDGHHAD_01954 1.6e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KMDGHHAD_01955 9.57e-288 yqxK - - L - - - DNA helicase
KMDGHHAD_01956 1.09e-136 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KMDGHHAD_01957 3.96e-109 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KMDGHHAD_01958 2.06e-46 - - - S - - - Protein of unknown function (DUF4227)
KMDGHHAD_01959 8.54e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
KMDGHHAD_01960 3.01e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KMDGHHAD_01961 4.34e-75 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
KMDGHHAD_01962 8.55e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KMDGHHAD_01963 8.59e-171 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMDGHHAD_01964 4.9e-145 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
KMDGHHAD_01965 1.75e-95 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
KMDGHHAD_01966 2.47e-137 spoVAEA - - S ko:K06407 - ko00000 Stage V sporulation protein AE
KMDGHHAD_01967 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
KMDGHHAD_01968 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KMDGHHAD_01969 9.1e-281 xylR - - GK - - - ROK family
KMDGHHAD_01970 3.74e-265 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KMDGHHAD_01971 9.52e-204 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
KMDGHHAD_01972 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KMDGHHAD_01973 4.05e-265 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KMDGHHAD_01974 1.39e-124 - - - S - - - NYN domain
KMDGHHAD_01975 1.06e-185 fnt - - P ko:K21993 - ko00000,ko02000 Formate nitrite
KMDGHHAD_01977 0.0 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KMDGHHAD_01978 5.58e-185 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
KMDGHHAD_01979 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_01980 6.62e-58 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KMDGHHAD_01981 5.11e-28 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KMDGHHAD_01982 8.2e-210 XK27_10120 - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
KMDGHHAD_01983 1.82e-158 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KMDGHHAD_01984 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
KMDGHHAD_01985 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMDGHHAD_01986 1.63e-278 adhB 1.1.1.1, 1.1.1.202 - C ko:K00001,ko:K00086 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KMDGHHAD_01987 0.0 - - - KT - - - Transcriptional regulator
KMDGHHAD_01988 0.0 - - - G - - - Domain of unknown function (DUF5110)
KMDGHHAD_01989 0.0 - - - S - - - Predicted membrane protein (DUF2339)
KMDGHHAD_01990 3.46e-157 cwlS - CBM50 M ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KMDGHHAD_01991 1.28e-77 - - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
KMDGHHAD_01992 3.08e-103 - - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
KMDGHHAD_01993 4.06e-145 - - - S - - - Protein of unknown function (DUF3237)
KMDGHHAD_01994 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KMDGHHAD_01995 0.0 - 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
KMDGHHAD_01996 4.79e-229 - - - EGP - - - Major facilitator Superfamily
KMDGHHAD_01997 2.15e-52 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 belongs to the aldehyde dehydrogenase family
KMDGHHAD_01998 4.1e-144 - - - P - - - Integral membrane protein TerC family
KMDGHHAD_01999 1.97e-87 - - - - - - - -
KMDGHHAD_02001 1.33e-200 XK27_04815 - - S ko:K07088 - ko00000 Membrane transport protein
KMDGHHAD_02002 0.0 - - - - - - - -
KMDGHHAD_02003 0.0 - - - V - - - COG1401 GTPase subunit of restriction endonuclease
KMDGHHAD_02004 4.15e-238 - - - - - - - -
KMDGHHAD_02005 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMDGHHAD_02006 2.26e-33 - - - S - - - Uncharacterized small protein (DUF2292)
KMDGHHAD_02007 1.62e-123 ssuE 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
KMDGHHAD_02008 1.97e-176 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
KMDGHHAD_02009 6.48e-166 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMDGHHAD_02010 1.44e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
KMDGHHAD_02011 1.52e-218 - - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMDGHHAD_02012 9.16e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KMDGHHAD_02013 1.45e-05 - - - - - - - -
KMDGHHAD_02014 3.69e-111 - - - S - - - SMI1-KNR4 cell-wall
KMDGHHAD_02015 6.67e-158 yflK - - S - - - protein conserved in bacteria
KMDGHHAD_02016 1.82e-144 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KMDGHHAD_02017 1.01e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KMDGHHAD_02018 6.89e-170 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KMDGHHAD_02019 7.41e-177 fabG5 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_02020 1.75e-95 - - - K - - - Acetyltransferase (GNAT) family
KMDGHHAD_02021 6.79e-120 - - - J - - - acetyltransferase
KMDGHHAD_02022 5.05e-121 yvbK - - K - - - acetyltransferase
KMDGHHAD_02023 1.39e-178 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
KMDGHHAD_02027 2.17e-205 - - - S - - - Methyltransferase domain
KMDGHHAD_02028 1.44e-218 icd 1.1.1.41, 1.1.1.42, 1.1.1.85 - CE ko:K00030,ko:K00031,ko:K00052 ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
KMDGHHAD_02030 5.69e-122 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KMDGHHAD_02031 1.75e-133 - - - S - - - oxidoreductase activity
KMDGHHAD_02033 2.79e-254 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KMDGHHAD_02037 1.28e-09 - - - S - - - Protein of unknown function (DUF4023)
KMDGHHAD_02038 1.07e-90 - - - E - - - Glyoxalase
KMDGHHAD_02039 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
KMDGHHAD_02040 6.61e-190 - 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KMDGHHAD_02041 7.25e-303 - - - G - - - Major facilitator superfamily
KMDGHHAD_02042 2.72e-191 - - - - - - - -
KMDGHHAD_02043 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMDGHHAD_02044 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMDGHHAD_02045 3.06e-94 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KMDGHHAD_02046 2.15e-131 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KMDGHHAD_02047 1.65e-70 yneR - - S - - - Belongs to the HesB IscA family
KMDGHHAD_02048 3.42e-69 yneQ - - - - - - -
KMDGHHAD_02049 1.91e-98 yneP - - S ko:K07107 - ko00000,ko01000 thioesterase
KMDGHHAD_02050 1.26e-42 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
KMDGHHAD_02051 4.72e-28 sspN - - S ko:K06431 - ko00000 Small acid-soluble spore protein N family
KMDGHHAD_02052 1.76e-06 - - - S - - - Fur-regulated basic protein B
KMDGHHAD_02053 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KMDGHHAD_02054 5.12e-306 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KMDGHHAD_02055 5.79e-52 - - - - - - - -
KMDGHHAD_02056 1.14e-26 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
KMDGHHAD_02057 5.89e-33 ydaS - - S - - - membrane
KMDGHHAD_02058 3.9e-149 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 lytic transglycosylase activity
KMDGHHAD_02059 0.0 alkK - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_02060 6.2e-142 - - - M - - - effector of murein hydrolase
KMDGHHAD_02061 4.43e-82 - - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
KMDGHHAD_02062 5.78e-57 - - - S - - - Small, acid-soluble spore proteins, alpha/beta type
KMDGHHAD_02063 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMDGHHAD_02064 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMDGHHAD_02065 4.07e-72 - - - S ko:K13628,ko:K15724 - ko00000,ko03016 Heme biosynthesis protein HemY
KMDGHHAD_02066 1.48e-305 ywoD - - EGP - - - Major facilitator superfamily
KMDGHHAD_02069 1.63e-194 - - - - - - - -
KMDGHHAD_02070 1.24e-258 yetN - - S - - - Protein of unknown function (DUF3900)
KMDGHHAD_02071 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_02072 3.71e-24 - - - - - - - -
KMDGHHAD_02073 5.83e-251 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
KMDGHHAD_02074 5.19e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
KMDGHHAD_02075 2.69e-88 - - - K - - - Helix-turn-helix domain
KMDGHHAD_02077 1.11e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
KMDGHHAD_02078 1.4e-300 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
KMDGHHAD_02079 0.0 citS 2.7.13.3 - T ko:K11637 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KMDGHHAD_02080 1.01e-156 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KMDGHHAD_02081 6.47e-303 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KMDGHHAD_02082 1.83e-234 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KMDGHHAD_02083 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KMDGHHAD_02086 1.55e-129 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KMDGHHAD_02087 3.84e-190 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KMDGHHAD_02088 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KMDGHHAD_02089 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KMDGHHAD_02090 5e-276 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMDGHHAD_02091 1.75e-157 - - - K ko:K10914,ko:K21828 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KMDGHHAD_02093 2.06e-169 - - - D ko:K07322 - ko00000 Di-iron-containing protein involved in the repair of iron-sulfur clusters
KMDGHHAD_02094 2.6e-124 - - - S - - - Belongs to the UPF0312 family
KMDGHHAD_02095 3.25e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KMDGHHAD_02097 3.89e-65 - - - P - - - Rhodanese domain protein
KMDGHHAD_02098 6.22e-52 csoR - - S - - - protein conserved in bacteria
KMDGHHAD_02099 1.48e-176 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
KMDGHHAD_02100 7.75e-94 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
KMDGHHAD_02101 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KMDGHHAD_02102 0.0 araP - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMDGHHAD_02103 1.19e-167 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KMDGHHAD_02104 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KMDGHHAD_02105 5.18e-272 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KMDGHHAD_02106 1.55e-253 chvE - - G ko:K10546 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMDGHHAD_02107 0.0 araG 3.6.3.17 - G ko:K10548 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KMDGHHAD_02108 3.18e-244 araH - - G ko:K10544,ko:K10547 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMDGHHAD_02109 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KMDGHHAD_02110 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KMDGHHAD_02111 3.43e-307 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KMDGHHAD_02112 0.0 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMDGHHAD_02113 7.74e-162 - - - I - - - Acyl-transferase
KMDGHHAD_02114 1.51e-259 - - - M - - - Glycosyl transferase family 2
KMDGHHAD_02115 1e-173 fabG9 - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_02116 4.62e-96 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
KMDGHHAD_02117 1.72e-116 solA 1.5.3.1 - E ko:K00301,ko:K02846 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
KMDGHHAD_02118 1.65e-86 solA 1.5.3.1 - E ko:K00301,ko:K02846 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
KMDGHHAD_02119 2.36e-96 yjbI - - S ko:K06886 - ko00000 COG2346 Truncated hemoglobins
KMDGHHAD_02120 2.09e-208 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KMDGHHAD_02121 1.8e-08 - - - - - - - -
KMDGHHAD_02122 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KMDGHHAD_02123 6.71e-307 coiA - - S ko:K06198 - ko00000 Competence protein
KMDGHHAD_02124 1.02e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMDGHHAD_02125 8.61e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KMDGHHAD_02126 1.38e-227 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_02127 1.81e-250 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_02128 2.61e-236 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMDGHHAD_02129 9.77e-206 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMDGHHAD_02130 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KMDGHHAD_02131 2.36e-59 - - - S - - - Domain of unknown function (DUF3899)
KMDGHHAD_02133 3.05e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KMDGHHAD_02134 2.24e-190 yjbA - - S - - - Belongs to the UPF0736 family
KMDGHHAD_02135 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KMDGHHAD_02136 9.14e-191 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
KMDGHHAD_02137 3.64e-223 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMDGHHAD_02138 4.46e-226 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_02139 9.27e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_02140 5.49e-193 yjaZ - - O - - - Zn-dependent protease
KMDGHHAD_02141 6.18e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMDGHHAD_02142 7.63e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMDGHHAD_02144 9.83e-186 - - - GM - - - ADP-glyceromanno-heptose 6-epimerase activity
KMDGHHAD_02145 4.87e-09 - - - S - - - Protein of unknown function (DUF2929)
KMDGHHAD_02146 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KMDGHHAD_02147 3.45e-37 yjzC - - S - - - YjzC-like protein
KMDGHHAD_02148 1.14e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
KMDGHHAD_02149 4.9e-201 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KMDGHHAD_02150 2.49e-35 - - - S - - - Protein of unknown function (DUF3813)
KMDGHHAD_02151 1.92e-204 yitS - - S - - - protein conserved in bacteria
KMDGHHAD_02152 5.96e-206 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02153 2.79e-136 yisN - - S - - - Protein of unknown function (DUF2777)
KMDGHHAD_02154 1.12e-78 yisL - - S - - - UPF0344 protein
KMDGHHAD_02155 7.6e-214 yisK 3.7.1.5 - Q ko:K16164 ko00350,ko01100,ko01120,map00350,map01100,map01120 ko00000,ko00001,ko01000 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KMDGHHAD_02156 2.95e-285 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KMDGHHAD_02157 5.22e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
KMDGHHAD_02158 1.03e-147 gerPC - - S ko:K06301 - ko00000 Spore germination protein
KMDGHHAD_02159 2.75e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
KMDGHHAD_02160 8.26e-96 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
KMDGHHAD_02161 2.62e-40 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
KMDGHHAD_02162 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KMDGHHAD_02163 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
KMDGHHAD_02164 3.03e-183 - - - S - - - Mitochondrial biogenesis AIM24
KMDGHHAD_02165 3.57e-125 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
KMDGHHAD_02167 6.23e-289 yhfN - - O - - - Peptidase M48
KMDGHHAD_02168 3.18e-56 - - - S - - - branched-chain amino acid
KMDGHHAD_02169 2.64e-153 ygaZ - - E - - - AzlC protein
KMDGHHAD_02170 0.0 lcfB_2 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Activates fatty acids by binding to coenzyme A
KMDGHHAD_02171 9.5e-238 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KMDGHHAD_02172 2.38e-29 yhfH - - S - - - YhfH-like protein
KMDGHHAD_02173 4.28e-84 ytkA - - S - - - YtkA-like
KMDGHHAD_02174 2.68e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KMDGHHAD_02175 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMDGHHAD_02176 1.7e-211 - - - EG - - - EamA-like transporter family
KMDGHHAD_02177 1.13e-307 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
KMDGHHAD_02178 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
KMDGHHAD_02179 4.62e-183 - - - K - - - DeoR C terminal sensor domain
KMDGHHAD_02180 1.04e-227 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KMDGHHAD_02181 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KMDGHHAD_02182 7.94e-134 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_02183 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KMDGHHAD_02184 2.07e-235 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KMDGHHAD_02185 1.14e-252 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KMDGHHAD_02186 7.85e-122 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KMDGHHAD_02187 6.74e-305 yhfA - - C - - - membrane
KMDGHHAD_02188 1.07e-285 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KMDGHHAD_02189 2.33e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KMDGHHAD_02190 3.54e-177 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
KMDGHHAD_02191 4.71e-98 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KMDGHHAD_02192 5.63e-108 trpP - - S - - - Tryptophan transporter TrpP
KMDGHHAD_02193 9.64e-49 yhaH - - S - - - YtxH-like protein
KMDGHHAD_02194 8.28e-135 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
KMDGHHAD_02195 1.19e-71 yhaI - - S - - - Protein of unknown function (DUF1878)
KMDGHHAD_02196 2.05e-197 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KMDGHHAD_02197 2.41e-37 yhaL - - S - - - Sporulation protein YhaL
KMDGHHAD_02198 7.73e-230 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
KMDGHHAD_02199 0.0 yhaN - - L - - - AAA domain
KMDGHHAD_02200 1.64e-304 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
KMDGHHAD_02201 9.57e-209 ycgQ - - S ko:K08986 - ko00000 membrane
KMDGHHAD_02202 3.16e-206 ycgR - - S ko:K07089 - ko00000 permeases
KMDGHHAD_02204 9.1e-165 - - - P - - - Integral membrane protein TerC family
KMDGHHAD_02205 7.99e-37 - - - S - - - YhzD-like protein
KMDGHHAD_02206 2.29e-179 yhaR - - I - - - enoyl-CoA hydratase
KMDGHHAD_02207 3.08e-207 yhaX - - S - - - hydrolases of the HAD superfamily
KMDGHHAD_02208 1.58e-72 yheA - - S - - - Belongs to the UPF0342 family
KMDGHHAD_02209 2.35e-266 yheB - - S - - - Belongs to the UPF0754 family
KMDGHHAD_02210 0.0 - - - HJ - - - YheC/D like ATP-grasp
KMDGHHAD_02211 2.19e-273 yheC - - HJ - - - YheC/D like ATP-grasp
KMDGHHAD_02212 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
KMDGHHAD_02213 4.25e-292 - - - HJ - - - COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
KMDGHHAD_02214 3.47e-212 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
KMDGHHAD_02215 1.92e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KMDGHHAD_02216 3.3e-39 B4168_3115 - - S ko:K06419 - ko00000 spore protein
KMDGHHAD_02217 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KMDGHHAD_02218 2.16e-22 - - - S - - - transposase or invertase
KMDGHHAD_02219 3.12e-115 - - - J - - - Acetyltransferase (GNAT) domain
KMDGHHAD_02221 4.14e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMDGHHAD_02223 9.02e-277 - - - G - - - Major Facilitator Superfamily
KMDGHHAD_02225 8.81e-240 ywcH1 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMDGHHAD_02226 9.96e-69 ykvR - - S - - - Protein of unknown function (DUF3219)
KMDGHHAD_02227 1.17e-271 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KMDGHHAD_02229 5.81e-218 - - - F - - - ATP-grasp domain
KMDGHHAD_02230 7.34e-59 - - - S - - - ATP-grasp domain
KMDGHHAD_02231 9.57e-87 - - - F - - - ATP-grasp domain
KMDGHHAD_02232 1.33e-269 - - - EGP - - - Major Facilitator Superfamily
KMDGHHAD_02233 5.64e-59 ltaA 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 L-allo-threonine aldolase activity
KMDGHHAD_02234 1.32e-161 - - - - - - - -
KMDGHHAD_02235 2.47e-77 - - - - - - - -
KMDGHHAD_02236 1.58e-138 - - - K - - - Transcriptional regulator
KMDGHHAD_02237 1.22e-132 - - - Q - - - Isochorismatase family
KMDGHHAD_02238 0.0 - - - EGP - - - Major facilitator superfamily
KMDGHHAD_02239 7.93e-278 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMDGHHAD_02240 8.76e-73 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
KMDGHHAD_02241 2.37e-124 XK27_04830 - - S - - - Protein of unknown function (DUF1700)
KMDGHHAD_02242 1.05e-153 - - - S - - - Putative adhesin
KMDGHHAD_02243 0.0 - - - NT ko:K03406,ko:K06595 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Chemoreceptor zinc-binding domain
KMDGHHAD_02244 1.02e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KMDGHHAD_02245 5.07e-202 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KMDGHHAD_02246 1.38e-254 - - - EGP - - - COG2814 Arabinose efflux permease
KMDGHHAD_02247 3.75e-98 - - - S - - - Threonine/Serine exporter, ThrE
KMDGHHAD_02248 5.6e-170 yjjP - - S - - - Putative threonine/serine exporter
KMDGHHAD_02249 6.69e-264 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KMDGHHAD_02250 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
KMDGHHAD_02251 3.01e-164 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KMDGHHAD_02252 0.0 lytS 2.7.13.3 - T ko:K02478,ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_02253 2.71e-197 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KMDGHHAD_02254 1.74e-145 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
KMDGHHAD_02255 4.57e-245 metN_1 - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KMDGHHAD_02256 8.38e-186 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KMDGHHAD_02257 5.36e-132 - - - - - - - -
KMDGHHAD_02258 1.11e-282 - - - NU ko:K18640 - ko00000,ko04812 Pilus assembly protein
KMDGHHAD_02259 6.78e-306 yisQ - - V - - - Mate efflux family protein
KMDGHHAD_02260 1.58e-197 gspA - - M - - - Glycosyl transferase family 8
KMDGHHAD_02261 1.24e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KMDGHHAD_02262 0.0 - - - EGP - - - the major facilitator superfamily
KMDGHHAD_02263 1.79e-287 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
KMDGHHAD_02264 0.0 poxB 1.2.5.1 - EH ko:K00156 ko00620,map00620 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KMDGHHAD_02265 4.29e-162 - 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMDGHHAD_02266 3.19e-157 - - - S - - - Nuclease-related domain
KMDGHHAD_02267 3.03e-257 - - - L - - - Transposase IS4 family protein
KMDGHHAD_02269 5.15e-214 - - - K - - - AraC-like ligand binding domain
KMDGHHAD_02270 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KMDGHHAD_02271 6.32e-315 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
KMDGHHAD_02272 8.8e-202 rhaD 4.1.2.19 - G ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KMDGHHAD_02273 4.15e-98 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
KMDGHHAD_02275 3.01e-46 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
KMDGHHAD_02276 1.08e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KMDGHHAD_02277 1.41e-301 - - - EGP - - - Major facilitator superfamily
KMDGHHAD_02278 0.0 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
KMDGHHAD_02279 7.06e-126 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KMDGHHAD_02280 4.72e-141 - - - Q ko:K22303 - ko00000,ko01000 Taurine catabolism dioxygenase TauD, TfdA family
KMDGHHAD_02281 1.23e-38 - - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KMDGHHAD_02282 2.29e-109 - 3.6.3.36 - P ko:K02049,ko:K10831 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMDGHHAD_02283 1.07e-171 - - - P ko:K15551 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
KMDGHHAD_02284 3.56e-134 - - - P ko:K15552 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMDGHHAD_02285 2.81e-134 - - - K - - - Acetyltransferase (GNAT) domain
KMDGHHAD_02286 1.53e-240 XK27_12525 - - S - - - AI-2E family transporter
KMDGHHAD_02287 1.21e-183 - - - S - - - hydrolases of the HAD superfamily
KMDGHHAD_02288 4.17e-293 - - - S ko:K07077 - ko00000 FAD binding domain
KMDGHHAD_02289 6.08e-52 - - - S ko:K07077 - ko00000 FAD binding domain
KMDGHHAD_02291 0.0 estB - - V - - - Belongs to the UPF0214 family
KMDGHHAD_02292 0.0 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KMDGHHAD_02293 1.38e-207 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
KMDGHHAD_02295 3.61e-185 - - - G - - - Major Facilitator Superfamily
KMDGHHAD_02296 5.37e-93 - - - C - - - Taurine catabolism dioxygenase TauD, TfdA family
KMDGHHAD_02297 1.22e-85 - - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMDGHHAD_02298 7.03e-40 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
KMDGHHAD_02299 5.88e-277 - 2.3.1.179 - IQ ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
KMDGHHAD_02300 1.62e-297 - - - T - - - His Kinase A (phosphoacceptor) domain
KMDGHHAD_02302 2.7e-68 - - - - - - - -
KMDGHHAD_02303 0.0 - - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KMDGHHAD_02304 3.69e-232 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
KMDGHHAD_02305 9.07e-167 - 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3 epimerase family
KMDGHHAD_02306 9.85e-209 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMDGHHAD_02307 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KMDGHHAD_02308 4.52e-140 - - - S - - - Domain of unkown function (DUF1775)
KMDGHHAD_02309 1.92e-217 - - - S - - - transposase or invertase
KMDGHHAD_02310 4.11e-13 - - - S - - - transposase or invertase
KMDGHHAD_02311 2.67e-116 - - - S - - - Pyridoxamine 5'phosphate oxidase-like, FMN-binding
KMDGHHAD_02312 4.13e-148 glnP9 - - E ko:K02029 - ko00000,ko00002,ko02000 amino acid ABC transporter
KMDGHHAD_02313 6.79e-152 glnP7 - - E ko:K02029 - ko00000,ko00002,ko02000 amino acid ABC transporter
KMDGHHAD_02314 5.85e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KMDGHHAD_02315 2.23e-196 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KMDGHHAD_02316 5.02e-276 - - - E - - - Alanine racemase, N-terminal domain
KMDGHHAD_02317 5.09e-264 - - - S - - - Domain of unknown function (DUF1611_N) Rossmann-like domain
KMDGHHAD_02318 1.11e-287 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase, C-terminal sheet domain
KMDGHHAD_02319 1.29e-305 LYS1 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Saccharopine dehydrogenase
KMDGHHAD_02320 1.22e-135 glnQ2 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMDGHHAD_02321 4.15e-119 - - - E ko:K02029 - ko00000,ko00002,ko02000 Transporter
KMDGHHAD_02322 3.96e-137 - - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KMDGHHAD_02323 2.28e-191 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMDGHHAD_02324 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KMDGHHAD_02325 4.67e-174 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
KMDGHHAD_02326 4.71e-56 - - - T - - - diguanylate cyclase activity
KMDGHHAD_02327 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KMDGHHAD_02328 0.0 - - - S ko:K06994,ko:K07003 - ko00000 MMPL domain protein
KMDGHHAD_02329 1.87e-127 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KMDGHHAD_02330 4.46e-147 yhhQ_2 - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KMDGHHAD_02331 0.0 - 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KMDGHHAD_02332 5.26e-15 - - - EGP - - - Major facilitator superfamily
KMDGHHAD_02333 9.99e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
KMDGHHAD_02334 9.48e-43 - - - - - - - -
KMDGHHAD_02335 4.08e-43 - - - S - - - Domain of unknown function (DUF4177)
KMDGHHAD_02336 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KMDGHHAD_02337 7.49e-197 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KMDGHHAD_02338 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMDGHHAD_02339 1.14e-139 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
KMDGHHAD_02340 3.02e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KMDGHHAD_02341 0.0 ykoS - - - - - - -
KMDGHHAD_02342 1.84e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KMDGHHAD_02343 1.5e-88 yngA - - S - - - GtrA-like protein
KMDGHHAD_02344 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KMDGHHAD_02345 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KMDGHHAD_02346 6.51e-161 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KMDGHHAD_02347 4.27e-38 - - - S - - - Domain of unknown function (DUF4305)
KMDGHHAD_02348 2.26e-167 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMDGHHAD_02349 1.97e-159 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KMDGHHAD_02351 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KMDGHHAD_02352 3.3e-236 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KMDGHHAD_02353 1.35e-106 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KMDGHHAD_02354 1.24e-165 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
KMDGHHAD_02355 1.41e-108 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
KMDGHHAD_02356 9.61e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KMDGHHAD_02357 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KMDGHHAD_02358 5.94e-282 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KMDGHHAD_02359 4.17e-107 yslB - - S - - - Protein of unknown function (DUF2507)
KMDGHHAD_02360 5.93e-135 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
KMDGHHAD_02361 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KMDGHHAD_02362 8.45e-193 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KMDGHHAD_02363 1.33e-114 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
KMDGHHAD_02364 3.8e-43 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_02366 2.11e-249 - - - S - - - Predicted membrane protein (DUF2157)
KMDGHHAD_02367 2.51e-120 - - - S - - - GDYXXLXY protein
KMDGHHAD_02368 9.88e-105 ysmB - - K - - - transcriptional
KMDGHHAD_02369 4.15e-191 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KMDGHHAD_02370 2.16e-43 yraG - - S ko:K06440 - ko00000 Spore Coat Protein
KMDGHHAD_02371 5.35e-81 yraF - - M - - - Spore coat protein
KMDGHHAD_02372 1.51e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMDGHHAD_02373 3.57e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
KMDGHHAD_02374 4.29e-32 yraE - - - ko:K06440 - ko00000 -
KMDGHHAD_02375 1.59e-245 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
KMDGHHAD_02376 3.72e-138 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KMDGHHAD_02377 4.92e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KMDGHHAD_02380 2.17e-62 - - - - - - - -
KMDGHHAD_02381 1.36e-95 - - - S - - - Protein of unknown function (DUF2512)
KMDGHHAD_02382 7.44e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMDGHHAD_02383 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KMDGHHAD_02384 2.29e-107 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KMDGHHAD_02385 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMDGHHAD_02386 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KMDGHHAD_02387 3.03e-169 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
KMDGHHAD_02388 3.68e-295 - - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KMDGHHAD_02390 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KMDGHHAD_02391 6.36e-162 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
KMDGHHAD_02392 4.09e-219 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
KMDGHHAD_02394 2.61e-105 fld - - C ko:K03839 - ko00000 Flavodoxin
KMDGHHAD_02395 3.57e-261 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KMDGHHAD_02396 1.44e-177 - - - T ko:K21562 - ko00000,ko03000 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KMDGHHAD_02397 0.0 - 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
KMDGHHAD_02398 2.49e-43 copZ - - P - - - Heavy-metal-associated domain
KMDGHHAD_02399 2.83e-161 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
KMDGHHAD_02400 2.25e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMDGHHAD_02401 3.65e-90 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KMDGHHAD_02402 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KMDGHHAD_02403 9.16e-197 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KMDGHHAD_02404 2.3e-202 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
KMDGHHAD_02406 6.29e-212 yojA - - EG ko:K03299 - ko00000,ko02000 Gluconate proton symporter
KMDGHHAD_02407 1.76e-238 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KMDGHHAD_02408 1.92e-89 - - - KT ko:K02647 - ko00000,ko03000 Sugar diacid utilization regulator
KMDGHHAD_02409 4.06e-245 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
KMDGHHAD_02410 9.23e-247 - - - U - - - protein localization to endoplasmic reticulum
KMDGHHAD_02411 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KMDGHHAD_02412 3.53e-110 - 1.97.1.4 - O ko:K04068 - ko00000,ko01000 4Fe-4S single cluster domain
KMDGHHAD_02413 1.05e-275 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMDGHHAD_02414 5.31e-151 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02416 3.08e-43 - - - - - - - -
KMDGHHAD_02417 1.01e-181 - - - E - - - G-D-S-L family
KMDGHHAD_02418 1.42e-215 bcrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_02419 2.02e-222 bcrB - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
KMDGHHAD_02420 5.02e-117 - - - - - - - -
KMDGHHAD_02421 3.52e-130 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
KMDGHHAD_02422 1.35e-184 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KMDGHHAD_02423 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase
KMDGHHAD_02424 4.81e-274 - 1.1.1.1 - C ko:K13954 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KMDGHHAD_02426 5.98e-209 - - - L ko:K07494 - ko00000 DDE superfamily endonuclease
KMDGHHAD_02428 8.69e-193 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
KMDGHHAD_02429 2.48e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMDGHHAD_02430 8.56e-151 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KMDGHHAD_02431 2.3e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KMDGHHAD_02432 1.08e-210 - 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KMDGHHAD_02433 4.51e-111 yhjR - - S - - - Rubrerythrin
KMDGHHAD_02434 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
KMDGHHAD_02435 8.32e-31 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_02436 3.16e-102 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMDGHHAD_02437 5.24e-92 - - - S - - - Protein of unknown function (DUF1232)
KMDGHHAD_02438 2.26e-06 - - - S ko:K06376 - ko00000 Spo0E like sporulation regulatory protein
KMDGHHAD_02439 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KMDGHHAD_02440 3.24e-228 ykvI - - S - - - membrane
KMDGHHAD_02441 9.45e-138 - - - S ko:K07052 - ko00000 Abortive infection protein
KMDGHHAD_02442 6.02e-37 ykvS - - S - - - protein conserved in bacteria
KMDGHHAD_02443 2.45e-48 - - - - - - - -
KMDGHHAD_02444 2.6e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
KMDGHHAD_02445 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMDGHHAD_02446 1.23e-179 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02447 1.84e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KMDGHHAD_02448 1.44e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KMDGHHAD_02449 4.51e-206 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
KMDGHHAD_02450 1.02e-112 ykyB - - S - - - YkyB-like protein
KMDGHHAD_02451 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KMDGHHAD_02452 1.33e-224 - - - T - - - Diguanylate cyclase
KMDGHHAD_02453 9.11e-158 - - - T - - - Diguanylate cyclase
KMDGHHAD_02454 9.15e-45 - - - - - - - -
KMDGHHAD_02455 8.69e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02456 5.57e-217 - 3.5.1.4 - C ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Acetamidase
KMDGHHAD_02457 7.13e-52 ykuJ - - S - - - protein conserved in bacteria
KMDGHHAD_02458 7.02e-103 ykuL - - S - - - CBS domain
KMDGHHAD_02459 4.04e-203 ccpC - - K - - - Transcriptional regulator
KMDGHHAD_02460 2.06e-122 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KMDGHHAD_02461 2.04e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KMDGHHAD_02462 1.25e-26 - - - S - - - YhfH-like protein
KMDGHHAD_02463 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMDGHHAD_02464 1.63e-39 ykzG - - S - - - Belongs to the UPF0356 family
KMDGHHAD_02465 3.06e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMDGHHAD_02466 2.48e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMDGHHAD_02467 1.41e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMDGHHAD_02468 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMDGHHAD_02469 5.15e-46 - - - - - - - -
KMDGHHAD_02470 9.82e-09 - - - S - - - SR1 protein
KMDGHHAD_02471 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
KMDGHHAD_02473 2.12e-63 yktA - - S - - - Belongs to the UPF0223 family
KMDGHHAD_02474 2.85e-153 yktB - - S - - - Belongs to the UPF0637 family
KMDGHHAD_02475 3.19e-33 - - - - - - - -
KMDGHHAD_02476 3.57e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
KMDGHHAD_02477 1.1e-34 - - - S - - - Family of unknown function (DUF5325)
KMDGHHAD_02478 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KMDGHHAD_02479 2.12e-70 ylaH - - S - - - YlaH-like protein
KMDGHHAD_02480 0.0 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
KMDGHHAD_02481 1.87e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KMDGHHAD_02482 1.4e-58 ylaN - - S - - - Belongs to the UPF0358 family
KMDGHHAD_02483 6.61e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KMDGHHAD_02484 7.37e-224 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KMDGHHAD_02485 1.21e-212 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMDGHHAD_02486 3.56e-259 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KMDGHHAD_02487 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMDGHHAD_02488 2.95e-147 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KMDGHHAD_02489 1.39e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KMDGHHAD_02490 1.95e-223 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
KMDGHHAD_02491 1.55e-83 ylbA - - S - - - YugN-like family
KMDGHHAD_02492 5.81e-249 ylbC - - S - - - protein with SCP PR1 domains
KMDGHHAD_02493 6.59e-111 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein, possibly involved in aromatic compounds catabolism
KMDGHHAD_02494 2.04e-91 ylbD - - S - - - Putative coat protein
KMDGHHAD_02495 5.16e-50 ylbE - - S - - - YlbE-like protein
KMDGHHAD_02496 2.52e-85 - - - - - - - -
KMDGHHAD_02497 3.1e-96 ylbF - - S - - - Belongs to the UPF0342 family
KMDGHHAD_02498 7.56e-62 ylbG - - S - - - UPF0298 protein
KMDGHHAD_02499 7.42e-89 - - - S - - - Methylthioribose kinase
KMDGHHAD_02500 1.08e-136 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KMDGHHAD_02501 6.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KMDGHHAD_02502 1.51e-278 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
KMDGHHAD_02503 1.43e-179 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KMDGHHAD_02504 6.18e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KMDGHHAD_02505 2.13e-312 ylbM - - S - - - Belongs to the UPF0348 family
KMDGHHAD_02506 9.36e-124 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KMDGHHAD_02507 7.12e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KMDGHHAD_02508 7.2e-109 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KMDGHHAD_02509 1.12e-119 ylbP - - K - - - n-acetyltransferase
KMDGHHAD_02510 2.95e-207 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMDGHHAD_02511 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KMDGHHAD_02512 1.96e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KMDGHHAD_02513 4.43e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KMDGHHAD_02514 1.18e-69 ftsL - - D - - - Essential cell division protein
KMDGHHAD_02515 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KMDGHHAD_02516 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
KMDGHHAD_02517 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KMDGHHAD_02518 6.04e-103 - - - M - - - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KMDGHHAD_02519 2.75e-219 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMDGHHAD_02520 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMDGHHAD_02521 1.17e-248 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KMDGHHAD_02522 9.87e-262 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMDGHHAD_02523 1.19e-156 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KMDGHHAD_02524 5.93e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KMDGHHAD_02525 1.59e-247 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KMDGHHAD_02526 1.54e-217 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KMDGHHAD_02527 1.19e-181 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 peptidase
KMDGHHAD_02528 2.14e-201 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KMDGHHAD_02529 7.33e-177 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KMDGHHAD_02531 8.82e-68 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KMDGHHAD_02532 8.76e-202 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KMDGHHAD_02533 5.23e-230 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KMDGHHAD_02534 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KMDGHHAD_02535 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KMDGHHAD_02536 8.95e-127 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KMDGHHAD_02538 8.14e-75 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
KMDGHHAD_02539 1.94e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
KMDGHHAD_02540 2.09e-290 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KMDGHHAD_02541 5.15e-79 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
KMDGHHAD_02543 2.93e-135 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KMDGHHAD_02545 5.71e-261 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KMDGHHAD_02546 0.0 - - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMDGHHAD_02547 1.78e-242 - - - T ko:K20971 ko02025,map02025 ko00000,ko00001,ko01001,ko02022 Diguanylate cyclase, GGDEF domain
KMDGHHAD_02549 2.64e-214 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMDGHHAD_02550 3.83e-202 - - - S - - - Nuclease-related domain
KMDGHHAD_02551 8.73e-60 - - - - - - - -
KMDGHHAD_02552 1.07e-39 - - - - - - - -
KMDGHHAD_02553 5.25e-209 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KMDGHHAD_02554 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KMDGHHAD_02555 7.15e-142 - - - M - - - Glycosyltransferase like family 2
KMDGHHAD_02556 1.58e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases C terminal
KMDGHHAD_02557 5.55e-220 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
KMDGHHAD_02558 1.56e-237 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases C terminal
KMDGHHAD_02559 1.5e-143 yhfK - - GM - - - NmrA-like family
KMDGHHAD_02560 4.91e-30 - - - - - - - -
KMDGHHAD_02561 2.24e-96 - - - S - - - protein conserved in bacteria
KMDGHHAD_02562 5.49e-197 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KMDGHHAD_02563 4.27e-224 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KMDGHHAD_02564 5.73e-61 yvlD - - S ko:K08972 - ko00000 Membrane
KMDGHHAD_02565 2.04e-229 yvlB - - S - - - Putative adhesin
KMDGHHAD_02566 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KMDGHHAD_02567 1.23e-187 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KMDGHHAD_02568 6.31e-295 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMDGHHAD_02569 9.55e-286 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMDGHHAD_02570 7.34e-95 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KMDGHHAD_02571 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KMDGHHAD_02572 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KMDGHHAD_02573 1.55e-15 - - - S - - - Uncharacterized conserved protein (DUF2164)
KMDGHHAD_02574 2.74e-46 csbA - - S - - - protein conserved in bacteria
KMDGHHAD_02575 3.57e-151 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
KMDGHHAD_02576 4.08e-17 - - - L ko:K07497 - ko00000 HTH-like domain
KMDGHHAD_02577 1.16e-50 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_02579 2.34e-151 XK27_07210 - - S - - - B3/4 domain
KMDGHHAD_02580 1.37e-115 - - - E - - - LysE type translocator
KMDGHHAD_02581 2.56e-126 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_02582 5.11e-290 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KMDGHHAD_02583 3.62e-78 - - - L - - - IstB-like ATP binding protein
KMDGHHAD_02584 5.43e-47 - - - L - - - IstB-like ATP binding protein
KMDGHHAD_02585 3.04e-92 - - - L - - - Integrase core domain
KMDGHHAD_02586 2.73e-54 - - - L - - - Integrase core domain
KMDGHHAD_02587 1.04e-31 - - - L - - - PFAM Integrase catalytic
KMDGHHAD_02589 4.37e-05 - - - S ko:K07076 - ko00000 DNA polymerase beta domain protein region
KMDGHHAD_02590 1.48e-98 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KMDGHHAD_02591 1.17e-273 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMDGHHAD_02592 7.14e-185 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KMDGHHAD_02593 4.82e-181 yycI - - S - - - protein conserved in bacteria
KMDGHHAD_02594 0.0 yycH - - S - - - protein conserved in bacteria
KMDGHHAD_02595 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KMDGHHAD_02596 5.26e-173 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMDGHHAD_02597 0.0 yfnA - - E ko:K03294 - ko00000 amino acid
KMDGHHAD_02598 1.34e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMDGHHAD_02599 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KMDGHHAD_02600 7.19e-177 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMDGHHAD_02601 6.65e-281 - - - QT ko:K09684 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_02602 0.0 - 2.6.1.55 - H ko:K15372 ko00410,ko00430,ko01100,map00410,map00430,map01100 ko00000,ko00001,ko01000 Aminotransferase class-III
KMDGHHAD_02603 3e-271 - - - C ko:K19954 - ko00000,ko01000 alcohol dehydrogenase
KMDGHHAD_02604 3.81e-294 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KMDGHHAD_02605 0.0 pucI - - FH ko:K03457 - ko00000 COG1953 Cytosine uracil thiamine allantoin permeases
KMDGHHAD_02606 0.0 gltD 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KMDGHHAD_02607 1.15e-299 preA 1.3.1.1 - CF ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 dihydroorotate dehydrogenase
KMDGHHAD_02608 0.0 hydA 3.5.2.2 - F ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Amidohydrolase family
KMDGHHAD_02610 0.0 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
KMDGHHAD_02611 9.71e-294 mtlA 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KMDGHHAD_02612 1.02e-202 mtlR - - K ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KMDGHHAD_02613 1.78e-171 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 Mannitol dehydrogenase Rossmann domain
KMDGHHAD_02614 2.47e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KMDGHHAD_02615 6.59e-143 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMDGHHAD_02617 6.35e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KMDGHHAD_02618 2.86e-315 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KMDGHHAD_02619 2.36e-246 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
KMDGHHAD_02620 7.95e-171 - - - G - - - Xylose isomerase domain protein TIM barrel
KMDGHHAD_02621 1.39e-230 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KMDGHHAD_02622 1.8e-307 - - - G ko:K03535 - ko00000,ko02000 Major Facilitator Superfamily
KMDGHHAD_02623 6.33e-132 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
KMDGHHAD_02624 1.49e-121 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
KMDGHHAD_02628 1.51e-234 - - - I - - - Alpha beta hydrolase
KMDGHHAD_02629 1.59e-93 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMDGHHAD_02631 5.69e-283 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMDGHHAD_02632 7.05e-270 - - - GK - - - ROK family
KMDGHHAD_02633 1.38e-179 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02634 0.0 - 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KMDGHHAD_02635 9.42e-313 - - - G - - - MFS/sugar transport protein
KMDGHHAD_02636 2.14e-46 - - - - - - - -
KMDGHHAD_02637 8.73e-175 - - - E - - - IrrE N-terminal-like domain
KMDGHHAD_02638 1.68e-78 - - - S - - - Helix-turn-helix
KMDGHHAD_02639 0.0 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 Peptidase M30
KMDGHHAD_02640 3.04e-118 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KMDGHHAD_02641 1.74e-308 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KMDGHHAD_02642 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
KMDGHHAD_02643 3.47e-166 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMDGHHAD_02644 5.06e-280 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KMDGHHAD_02645 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMDGHHAD_02646 1.2e-238 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMDGHHAD_02647 6.4e-54 XAC3035 - - O ko:K06191 - ko00000 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KMDGHHAD_02648 2.04e-309 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KMDGHHAD_02650 1.09e-05 copA 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
KMDGHHAD_02651 1.58e-111 - - - S - - - Protein of unknown function (DUF1641)
KMDGHHAD_02653 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
KMDGHHAD_02654 4.69e-43 - - - - - - - -
KMDGHHAD_02656 1.33e-292 - - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
KMDGHHAD_02658 3.54e-277 - 1.5.3.1 - E ko:K00303 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
KMDGHHAD_02659 0.0 - - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMDGHHAD_02660 3.08e-213 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 ornithine cyclodeaminase
KMDGHHAD_02663 1.75e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
KMDGHHAD_02664 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KMDGHHAD_02665 1.11e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
KMDGHHAD_02666 5.46e-113 - - - K - - - Bacterial transcription activator, effector binding domain
KMDGHHAD_02669 9.05e-85 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KMDGHHAD_02670 1.5e-40 - - - K - - - Helix-turn-helix XRE-family like proteins
KMDGHHAD_02671 1.18e-250 yqjM1 - - C - - - Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KMDGHHAD_02672 3.76e-211 - - - S - - - reductase
KMDGHHAD_02673 2.52e-202 dkgB - - S - - - Aldo/keto reductase family
KMDGHHAD_02674 4.58e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
KMDGHHAD_02675 1.67e-222 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KMDGHHAD_02676 4.25e-128 - - - C - - - Nitroreductase family
KMDGHHAD_02677 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_02678 4.11e-25 - - - - - - - -
KMDGHHAD_02679 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
KMDGHHAD_02680 0.0 lysP - - E ko:K11733 - ko00000,ko02000 amino acid
KMDGHHAD_02681 1.6e-128 - - - K - - - Cupin domain
KMDGHHAD_02682 8.87e-269 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K02052,ko:K11072 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KMDGHHAD_02683 2.89e-179 potB - - E ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1176 ABC-type spermidine putrescine transport system, permease component I
KMDGHHAD_02684 7.93e-179 potC - - E ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1177 ABC-type spermidine putrescine transport system, permease component II
KMDGHHAD_02685 1.06e-260 potD - - E ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0687 Spermidine putrescine-binding periplasmic protein
KMDGHHAD_02686 1.08e-248 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KMDGHHAD_02689 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
KMDGHHAD_02690 4.07e-138 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_02691 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KMDGHHAD_02692 0.0 - - - S - - - Protein of unknown function (DUF2397)
KMDGHHAD_02693 3.36e-295 - - - S - - - Protein of unknown function (DUF2398)
KMDGHHAD_02694 0.0 - - - D - - - Putative exonuclease SbcCD, C subunit
KMDGHHAD_02695 0.0 - - - S - - - Protein of unknown function N-terminus (DUF3323)
KMDGHHAD_02696 2.66e-112 - - - - - - - -
KMDGHHAD_02698 1.33e-270 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KMDGHHAD_02699 2.24e-202 yoaT - - S - - - Protein of unknown function (DUF817)
KMDGHHAD_02700 8.52e-41 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_02701 9.63e-100 yoaS - - S - - - Protein of unknown function (DUF2975)
KMDGHHAD_02702 4.88e-79 - - - - ko:K06327 - ko00000 -
KMDGHHAD_02703 2.08e-302 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMDGHHAD_02704 3.22e-98 - - - S ko:K09793 - ko00000 protein conserved in bacteria
KMDGHHAD_02705 0.0 - - - S ko:K08981 - ko00000 Bacterial PH domain
KMDGHHAD_02706 1.04e-112 - - - S ko:K09167 - ko00000 Bacterial PH domain
KMDGHHAD_02707 9.58e-117 - - - S - - - AAA domain
KMDGHHAD_02708 3.02e-44 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
KMDGHHAD_02709 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
KMDGHHAD_02710 3.47e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMDGHHAD_02711 4.5e-66 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMDGHHAD_02712 1.62e-187 - 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KMDGHHAD_02713 4.04e-204 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KMDGHHAD_02714 3.32e-240 fabH5 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
KMDGHHAD_02715 8.01e-77 - - - - - - - -
KMDGHHAD_02717 0.0 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KMDGHHAD_02720 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KMDGHHAD_02721 1.24e-130 - - - K - - - Iron dependent repressor, N-terminal DNA binding domain
KMDGHHAD_02722 4.71e-56 - - - - - - - -
KMDGHHAD_02723 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMDGHHAD_02724 1.33e-196 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMDGHHAD_02725 1.57e-187 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
KMDGHHAD_02726 2.58e-37 yfjT - - - - - - -
KMDGHHAD_02727 1.34e-189 yfkD - - S - - - YfkD-like protein
KMDGHHAD_02729 1.01e-231 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
KMDGHHAD_02730 8.75e-281 yfkF - - EGP - - - Major facilitator superfamily
KMDGHHAD_02731 6.56e-189 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KMDGHHAD_02732 1.12e-42 yfkK - - S - - - Belongs to the UPF0435 family
KMDGHHAD_02733 1.63e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KMDGHHAD_02734 1.92e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KMDGHHAD_02735 1.3e-176 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KMDGHHAD_02736 1.21e-173 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KMDGHHAD_02737 3.26e-76 ydhN1 - - S - - - Domain of unknown function (DUF1992)
KMDGHHAD_02739 1.11e-77 yeaO - - S - - - Protein of unknown function, DUF488
KMDGHHAD_02740 3.62e-287 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KMDGHHAD_02741 3.05e-186 yteA - - T - - - COG1734 DnaK suppressor protein
KMDGHHAD_02742 1.63e-110 ykhA - - I - - - Acyl-CoA hydrolase
KMDGHHAD_02743 1.9e-232 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KMDGHHAD_02744 4.82e-248 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
KMDGHHAD_02745 3.88e-116 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
KMDGHHAD_02746 8.59e-272 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KMDGHHAD_02747 1.6e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
KMDGHHAD_02748 3.29e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KMDGHHAD_02749 1.4e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
KMDGHHAD_02750 1.22e-131 - 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KMDGHHAD_02752 1.45e-162 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KMDGHHAD_02754 0.0 - - - K - - - helix_turn_helix, Lux Regulon
KMDGHHAD_02755 1.11e-139 - - - - - - - -
KMDGHHAD_02756 2.92e-89 - - - S - - - response to pH
KMDGHHAD_02757 5.33e-134 - - - - - - - -
KMDGHHAD_02758 9.99e-196 ypuA - - S - - - Secreted protein
KMDGHHAD_02759 4.82e-276 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KMDGHHAD_02760 1.67e-291 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMDGHHAD_02761 1.64e-141 gpmB - - G ko:K15640 - ko00000 Histidine phosphatase superfamily (branch 1)
KMDGHHAD_02762 4.86e-92 - - - K - - - Transcriptional
KMDGHHAD_02764 2.21e-140 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMDGHHAD_02765 2.97e-131 yjbK - - S - - - protein conserved in bacteria
KMDGHHAD_02766 2.23e-80 yjbL - - S - - - Belongs to the UPF0738 family
KMDGHHAD_02767 2.41e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
KMDGHHAD_02768 4.53e-197 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMDGHHAD_02769 3.59e-207 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KMDGHHAD_02770 3.71e-182 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KMDGHHAD_02771 3.26e-181 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KMDGHHAD_02774 5.8e-110 - - - S ko:K06343,ko:K06344 - ko00000 Spore coat protein
KMDGHHAD_02775 1.1e-78 yjcA - - S - - - Protein of unknown function (DUF1360)
KMDGHHAD_02777 1.4e-105 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMDGHHAD_02778 2.91e-109 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
KMDGHHAD_02779 2.45e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
KMDGHHAD_02780 2.49e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
KMDGHHAD_02783 4.06e-146 - - - M - - - Methyltransferase
KMDGHHAD_02784 1.41e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KMDGHHAD_02785 2.2e-44 - - - S - - - Protein of unknown function DUF86
KMDGHHAD_02786 8.27e-52 - - - S - - - Nucleotidyltransferase domain
KMDGHHAD_02787 2.45e-246 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KMDGHHAD_02789 2.25e-106 - 1.1.1.53 - IQ ko:K00038 ko00140,ko01100,map00140,map01100 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02790 2.83e-52 - - - S - - - Protein of unknown function (DUF2750)
KMDGHHAD_02791 7.23e-28 mutR - - K - - - Transcriptional activator, Rgg GadR MutR family
KMDGHHAD_02792 2.01e-140 - - - EGP - - - Major Facilitator
KMDGHHAD_02793 6.61e-182 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_02794 2.25e-203 - - - S - - - Protein of unknown function
KMDGHHAD_02795 3.19e-182 - - - S - - - Protein of unknown function (DUF2961)
KMDGHHAD_02796 1.51e-138 - - - K ko:K19505 - ko00000,ko03000 PFAM sigma-54 factor interaction domain-containing protein
KMDGHHAD_02797 0.0 - - - K ko:K19505 - ko00000,ko03000 PTS system fructose IIA component
KMDGHHAD_02798 7.39e-56 - - - K ko:K19505 - ko00000,ko03000 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KMDGHHAD_02799 7.04e-13 - - - L ko:K07494 - ko00000 DDE superfamily endonuclease
KMDGHHAD_02801 1.05e-68 - - - Q - - - Isochorismatase family
KMDGHHAD_02802 1.65e-122 - - - S - - - S4 RNA-binding domain
KMDGHHAD_02803 3.34e-244 - - - - - - - -
KMDGHHAD_02804 6.27e-49 yxjI - - S - - - LURP-one-related
KMDGHHAD_02805 4.74e-23 yxjI - - S - - - LURP-one-related
KMDGHHAD_02806 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMDGHHAD_02807 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMDGHHAD_02808 1.95e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMDGHHAD_02810 3.88e-199 - - - Q - - - N-acetyltransferase
KMDGHHAD_02811 1.59e-155 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMDGHHAD_02812 7.67e-177 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMDGHHAD_02813 2.63e-58 ylmC - - S - - - sporulation protein
KMDGHHAD_02814 1.49e-114 - - - M - - - 3D domain
KMDGHHAD_02815 3.58e-199 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
KMDGHHAD_02816 1.97e-158 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KMDGHHAD_02817 2.44e-99 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KMDGHHAD_02818 3e-54 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
KMDGHHAD_02819 6.37e-185 ylmH - - S - - - conserved protein, contains S4-like domain
KMDGHHAD_02820 8.55e-97 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KMDGHHAD_02821 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KMDGHHAD_02823 2.35e-107 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMDGHHAD_02824 1.18e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KMDGHHAD_02825 3e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KMDGHHAD_02826 1.33e-120 - - - - ko:K02004 - ko00000,ko00002,ko02000 -
KMDGHHAD_02827 6.17e-156 - - - EGP - - - Transmembrane secretion effector
KMDGHHAD_02828 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
KMDGHHAD_02829 1.44e-199 yxxF - - EG - - - EamA-like transporter family
KMDGHHAD_02830 1.35e-263 adhC 1.1.1.1, 1.1.1.90 - C ko:K00001,ko:K00055 ko00010,ko00071,ko00350,ko00360,ko00622,ko00623,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00360,map00622,map00623,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
KMDGHHAD_02832 5.12e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMDGHHAD_02833 2.45e-39 yetF3 - - K - - - membrane
KMDGHHAD_02834 4.12e-31 yetF3 - - K - - - membrane
KMDGHHAD_02841 3.29e-234 yaaC - - S - - - YaaC-like Protein
KMDGHHAD_02842 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KMDGHHAD_02843 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KMDGHHAD_02844 9.82e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KMDGHHAD_02845 2.28e-133 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KMDGHHAD_02846 1.44e-292 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KMDGHHAD_02848 2.42e-162 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
KMDGHHAD_02849 6.43e-153 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
KMDGHHAD_02850 0.0 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KMDGHHAD_02851 1.21e-103 crr - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KMDGHHAD_02852 6.36e-108 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KMDGHHAD_02853 1.38e-111 - - - E - - - LysE type translocator
KMDGHHAD_02854 2.19e-234 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMDGHHAD_02855 6.39e-34 - - - O - - - Glutaredoxin-like domain (DUF836)
KMDGHHAD_02856 9.12e-110 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMDGHHAD_02857 6.15e-124 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 amino acid
KMDGHHAD_02858 5.73e-89 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KMDGHHAD_02859 1.91e-117 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
KMDGHHAD_02860 4.36e-129 tcyK - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 L-cystine-binding protein
KMDGHHAD_02861 3.42e-133 - - - ET ko:K02030,ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KMDGHHAD_02862 2.07e-73 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KMDGHHAD_02863 6.03e-48 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
KMDGHHAD_02864 2.94e-115 ytlI - - K ko:K21960 - ko00000,ko03000 Bacterial regulatory helix-turn-helix protein, lysR family
KMDGHHAD_02865 0.0 hemG 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KMDGHHAD_02866 4.17e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KMDGHHAD_02867 5.24e-209 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KMDGHHAD_02868 3.7e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KMDGHHAD_02869 9.79e-194 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMDGHHAD_02870 3.27e-184 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMDGHHAD_02872 1.17e-220 - - - M - - - Glycosyltransferase like family 2
KMDGHHAD_02873 0.0 - - - - - - - -
KMDGHHAD_02874 3.85e-74 - - - P - - - EamA-like transporter family
KMDGHHAD_02875 9.05e-67 - - - S ko:K12962 ko01503,map01503 ko00000,ko00001,ko00002,ko01005,ko02000 EamA-like transporter family
KMDGHHAD_02876 1.05e-187 - - - P - - - Major facilitator superfamily
KMDGHHAD_02878 1.31e-121 - - - - - - - -
KMDGHHAD_02879 8.46e-242 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMDGHHAD_02880 6.61e-180 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KMDGHHAD_02881 1.25e-241 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KMDGHHAD_02882 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
KMDGHHAD_02883 2.91e-09 - - - - ko:K07213 ko04978,map04978 ko00000,ko00001 -
KMDGHHAD_02884 2.28e-219 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMDGHHAD_02885 1.78e-308 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KMDGHHAD_02886 8.23e-247 yeeE - - S ko:K07112 - ko00000 Sulphur transport
KMDGHHAD_02887 1.21e-48 yeeD - - O - - - Belongs to the sulfur carrier protein TusA family
KMDGHHAD_02888 2.51e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KMDGHHAD_02889 2.91e-165 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KMDGHHAD_02890 2.06e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KMDGHHAD_02891 3.29e-187 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KMDGHHAD_02892 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
KMDGHHAD_02893 2.98e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KMDGHHAD_02894 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KMDGHHAD_02895 6.01e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KMDGHHAD_02896 2.29e-180 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KMDGHHAD_02897 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
KMDGHHAD_02898 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
KMDGHHAD_02899 2.21e-231 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
KMDGHHAD_02900 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KMDGHHAD_02901 4.77e-42 - - - - - - - -
KMDGHHAD_02902 4.31e-177 pdaB - - G - - - xylanase chitin deacetylase
KMDGHHAD_02903 4.06e-238 - - - S - - - Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
KMDGHHAD_02905 4.13e-140 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
KMDGHHAD_02906 4.54e-112 gerD - - S ko:K06294 - ko00000 Spore gernimation protein
KMDGHHAD_02907 5.43e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KMDGHHAD_02908 2.59e-169 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KMDGHHAD_02909 1.73e-107 ybaK - - S - - - Protein of unknown function (DUF2521)
KMDGHHAD_02910 0.0 lysP - - E ko:K11733 - ko00000,ko02000 amino acid
KMDGHHAD_02911 6.21e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KMDGHHAD_02912 9.55e-289 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KMDGHHAD_02914 0.0 - - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
KMDGHHAD_02915 1.74e-124 - 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMDGHHAD_02916 2.22e-272 - 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMDGHHAD_02917 1.36e-28 - 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KMDGHHAD_02918 1.05e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KMDGHHAD_02919 3.24e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KMDGHHAD_02920 5.67e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KMDGHHAD_02921 2.18e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMDGHHAD_02922 4.72e-207 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMDGHHAD_02923 8.45e-202 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMDGHHAD_02925 8.7e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KMDGHHAD_02926 9.96e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMDGHHAD_02927 9.37e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KMDGHHAD_02928 6.28e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KMDGHHAD_02929 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KMDGHHAD_02930 3.31e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KMDGHHAD_02931 1.14e-292 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KMDGHHAD_02932 3.48e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KMDGHHAD_02933 2.65e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KMDGHHAD_02934 5.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMDGHHAD_02935 1.22e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KMDGHHAD_02936 1.76e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KMDGHHAD_02937 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KMDGHHAD_02938 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMDGHHAD_02939 9.01e-121 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KMDGHHAD_02940 2.15e-75 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KMDGHHAD_02941 1.48e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KMDGHHAD_02942 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KMDGHHAD_02943 2.44e-36 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KMDGHHAD_02944 2.03e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KMDGHHAD_02945 7.14e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KMDGHHAD_02946 2.75e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KMDGHHAD_02947 1.16e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KMDGHHAD_02948 1.46e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KMDGHHAD_02949 3.56e-57 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KMDGHHAD_02950 8.08e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KMDGHHAD_02951 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KMDGHHAD_02952 1.82e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KMDGHHAD_02953 8.83e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KMDGHHAD_02954 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KMDGHHAD_02955 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KMDGHHAD_02956 2.06e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KMDGHHAD_02957 5.27e-49 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
KMDGHHAD_02958 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMDGHHAD_02959 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMDGHHAD_02960 5.13e-144 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KMDGHHAD_02961 1.94e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KMDGHHAD_02962 5.97e-106 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KMDGHHAD_02964 6.58e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KMDGHHAD_02965 2.39e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KMDGHHAD_02966 9.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KMDGHHAD_02967 6.36e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KMDGHHAD_02968 3.83e-147 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KMDGHHAD_02969 5.27e-117 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KMDGHHAD_02970 2.48e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMDGHHAD_02971 1.88e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KMDGHHAD_02972 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KMDGHHAD_02973 5.88e-154 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
KMDGHHAD_02974 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMDGHHAD_02975 2.39e-108 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KMDGHHAD_02976 1.01e-156 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KMDGHHAD_02977 8.64e-253 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
KMDGHHAD_02978 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KMDGHHAD_02979 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KMDGHHAD_02980 7.06e-249 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KMDGHHAD_02981 1.34e-132 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
KMDGHHAD_02982 6.38e-97 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KMDGHHAD_02984 7.37e-60 - - - S - - - Protein of unknown function (DUF3969)
KMDGHHAD_02985 9.26e-290 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMDGHHAD_02986 3.57e-211 fatD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMDGHHAD_02987 2.06e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMDGHHAD_02988 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_02989 6.84e-226 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KMDGHHAD_02990 6.09e-57 fdxA - - C - - - 4Fe-4S binding domain
KMDGHHAD_02991 5.47e-35 - - - S - - - Family of unknown function (DUF5316)
KMDGHHAD_02992 2.13e-160 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMDGHHAD_02993 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KMDGHHAD_02994 9.18e-242 cnpD2 - - T - - - HD domain
KMDGHHAD_02995 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
KMDGHHAD_02997 0.0 ydaO - - E - - - amino acid
KMDGHHAD_02998 3.25e-188 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KMDGHHAD_02999 1.83e-33 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMDGHHAD_03000 1.02e-218 ydbI - - S - - - AI-2E family transporter
KMDGHHAD_03001 9.76e-172 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KMDGHHAD_03002 2.08e-176 glnH - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KMDGHHAD_03003 1.04e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMDGHHAD_03004 3.08e-151 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KMDGHHAD_03005 1.04e-90 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
KMDGHHAD_03006 1.01e-251 - - - S - - - Protein of unknown function (DUF1648)
KMDGHHAD_03007 1.25e-72 yodB - - K - - - transcriptional
KMDGHHAD_03009 8.46e-301 - - - S - - - SNARE associated Golgi protein
KMDGHHAD_03010 1.16e-135 yngC - - S - - - membrane-associated protein
KMDGHHAD_03011 2.13e-209 msrR - - K - - - COG1316 Transcriptional regulator
KMDGHHAD_03013 1.16e-133 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KMDGHHAD_03014 6.85e-55 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
KMDGHHAD_03015 1.17e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KMDGHHAD_03016 9.76e-230 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KMDGHHAD_03017 3.35e-215 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KMDGHHAD_03018 1.35e-111 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Nudix hydrolase
KMDGHHAD_03019 6.59e-227 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KMDGHHAD_03020 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
KMDGHHAD_03021 1.25e-114 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KMDGHHAD_03022 1.4e-154 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KMDGHHAD_03024 1.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KMDGHHAD_03027 4.44e-223 nodB1 - - G - - - deacetylase
KMDGHHAD_03029 2.92e-37 yhjQ - - C - - - COG1145 Ferredoxin
KMDGHHAD_03031 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMDGHHAD_03032 3.42e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
KMDGHHAD_03033 3.6e-285 - - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KMDGHHAD_03034 1.46e-97 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMDGHHAD_03035 1.3e-90 - - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KMDGHHAD_03036 7.56e-52 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KMDGHHAD_03037 4.43e-214 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KMDGHHAD_03038 3.35e-127 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 RecB family exonuclease
KMDGHHAD_03039 1.04e-172 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein
KMDGHHAD_03040 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
KMDGHHAD_03041 1.11e-148 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
KMDGHHAD_03042 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Metal dependent phosphohydrolases with conserved 'HD' motif.
KMDGHHAD_03043 1.84e-188 mleR - - K - - - LysR substrate binding domain
KMDGHHAD_03044 0.0 sfcA 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
KMDGHHAD_03045 8.27e-25 mleP - - S ko:K07088 - ko00000 auxin efflux carrier
KMDGHHAD_03046 7.75e-144 mleP - - S ko:K07088 - ko00000 Membrane transport protein
KMDGHHAD_03048 1.27e-165 - - - K - - - Helix-turn-helix domain, rpiR family
KMDGHHAD_03049 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KMDGHHAD_03050 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMDGHHAD_03051 1.67e-127 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KMDGHHAD_03052 6.27e-249 - - - S - - - Metallo-beta-lactamase superfamily
KMDGHHAD_03053 5.76e-136 - - - K - - - Bacterial regulatory proteins, tetR family
KMDGHHAD_03054 0.0 - 1.3.1.31 - C ko:K10797 ko00360,ko01120,map00360,map01120 ko00000,ko00001,ko01000 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KMDGHHAD_03055 5.22e-16 - - - S - - - PFAM Uncharacterised protein family UPF0236
KMDGHHAD_03056 5.3e-264 ysdC - - G - - - COG1363 Cellulase M and related proteins
KMDGHHAD_03058 1.97e-59 - - - - - - - -
KMDGHHAD_03059 9.95e-61 - - - T - - - ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMDGHHAD_03060 1.86e-163 - - - - - - - -
KMDGHHAD_03061 2.86e-57 - - - - - - - -
KMDGHHAD_03063 0.0 - - - FH ko:K03457 - ko00000 Permease for cytosine/purines, uracil, thiamine, allantoin
KMDGHHAD_03064 9.45e-104 yjhE - - S - - - Phage tail protein
KMDGHHAD_03065 1.29e-172 - - - GKT ko:K03483 - ko00000,ko03000 transcriptional antiterminator
KMDGHHAD_03066 8.19e-47 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system, galactitol-specific IIB component
KMDGHHAD_03067 1.92e-262 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KMDGHHAD_03068 0.0 mqo 1.1.5.4 - S ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 malate quinone oxidoreductase
KMDGHHAD_03069 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KMDGHHAD_03070 3.84e-107 - - - V - - - Type I restriction modification DNA specificity domain
KMDGHHAD_03071 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
KMDGHHAD_03072 0.0 - - - S - - - Zinc finger, swim domain protein
KMDGHHAD_03073 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMDGHHAD_03075 3.69e-92 ywpF - - S - - - YwpF-like protein
KMDGHHAD_03076 5.41e-84 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KMDGHHAD_03078 4.3e-96 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KMDGHHAD_03079 1.5e-192 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KMDGHHAD_03080 7.44e-186 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KMDGHHAD_03081 4.13e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
KMDGHHAD_03082 3.27e-57 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
KMDGHHAD_03083 7.35e-174 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KMDGHHAD_03084 4.86e-235 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
KMDGHHAD_03085 2.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMDGHHAD_03086 2.39e-174 ywmB - - S - - - TATA-box binding
KMDGHHAD_03087 1.1e-46 ywzB - - S - - - membrane
KMDGHHAD_03088 1.03e-87 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KMDGHHAD_03089 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KMDGHHAD_03090 9.39e-196 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KMDGHHAD_03091 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KMDGHHAD_03092 2.12e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMDGHHAD_03093 2.3e-72 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KMDGHHAD_03094 1.21e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMDGHHAD_03095 4.65e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KMDGHHAD_03096 1.92e-75 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase I chain
KMDGHHAD_03097 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KMDGHHAD_03098 1.21e-304 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KMDGHHAD_03099 1.13e-127 ywlG - - S - - - Belongs to the UPF0340 family
KMDGHHAD_03100 4.42e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
KMDGHHAD_03101 6.15e-269 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Chemotaxis
KMDGHHAD_03102 5.54e-105 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMDGHHAD_03103 2.27e-116 mntP - - P - - - Probably functions as a manganese efflux pump
KMDGHHAD_03104 1.66e-246 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KMDGHHAD_03105 1.87e-170 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
KMDGHHAD_03106 2.62e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KMDGHHAD_03107 1.48e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KMDGHHAD_03109 4.8e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KMDGHHAD_03110 2.24e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KMDGHHAD_03111 7.11e-293 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KMDGHHAD_03112 1.74e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
KMDGHHAD_03113 5.13e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMDGHHAD_03114 3.7e-149 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KMDGHHAD_03115 1.58e-203 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
KMDGHHAD_03116 2.03e-80 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
KMDGHHAD_03117 1.3e-262 - - - - - - - -
KMDGHHAD_03118 5.82e-186 - - - - - - - -
KMDGHHAD_03119 1.14e-159 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KMDGHHAD_03120 3.35e-87 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
KMDGHHAD_03121 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KMDGHHAD_03122 4.48e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KMDGHHAD_03123 2.59e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KMDGHHAD_03124 0.0 - - - S ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KMDGHHAD_03125 0.0 icmF 5.4.99.13 - EI ko:K11942 - ko00000,ko01000 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KMDGHHAD_03126 3.71e-147 kstR2_2 - - K - - - Transcriptional regulator
KMDGHHAD_03127 1.6e-269 acdA 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 acyl-CoA dehydrogenase
KMDGHHAD_03128 6.5e-268 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
KMDGHHAD_03129 9.36e-275 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
KMDGHHAD_03130 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
KMDGHHAD_03131 1.24e-278 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KMDGHHAD_03132 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KMDGHHAD_03133 4.59e-98 ywiB - - S - - - protein conserved in bacteria
KMDGHHAD_03134 9.99e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KMDGHHAD_03135 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KMDGHHAD_03136 3.07e-119 ywhD - - S - - - YwhD family
KMDGHHAD_03137 2.4e-152 ywhC - - S - - - Peptidase M50
KMDGHHAD_03138 2.69e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
KMDGHHAD_03139 4.18e-118 ywgA - - - ko:K09388 - ko00000 -
KMDGHHAD_03140 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
KMDGHHAD_03142 5.16e-139 rsfA - - S ko:K06314 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_03143 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KMDGHHAD_03144 9.1e-261 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KMDGHHAD_03145 5.71e-192 - - - - - - - -
KMDGHHAD_03146 5.74e-301 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KMDGHHAD_03147 1.34e-108 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
KMDGHHAD_03148 0.0 - - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KMDGHHAD_03150 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KMDGHHAD_03151 0.0 comM - - O ko:K07391 - ko00000 Mg chelatase subunit ChlI
KMDGHHAD_03152 1.69e-197 - - - S - - - transposase or invertase
KMDGHHAD_03153 3.69e-30 - - - - - - - -
KMDGHHAD_03154 2.49e-256 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
KMDGHHAD_03155 1.81e-316 xylT - - U ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KMDGHHAD_03156 1.66e-84 - - - E - - - COG1113 Gamma-aminobutyrate permease and related permeases
KMDGHHAD_03158 2.8e-311 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KMDGHHAD_03159 6.64e-187 - - - G ko:K10709 - ko00000 myo-inosose-2 dehydratase activity
KMDGHHAD_03160 1.62e-191 - - - G - - - Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KMDGHHAD_03161 1.52e-145 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KMDGHHAD_03162 2.19e-125 - - - K ko:K02443 - ko00000,ko03000 Glycerol-3-phosphate responsive antiterminator
KMDGHHAD_03163 6.08e-236 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMDGHHAD_03164 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMDGHHAD_03165 1.23e-313 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 O-acetylhomoserine
KMDGHHAD_03166 5.45e-232 - 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KMDGHHAD_03167 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KMDGHHAD_03169 4.53e-264 crtQ - - M ko:K10211 ko00906,map00906 ko00000,ko00001,ko01000 Glycosyl transferase family 21
KMDGHHAD_03170 5.73e-143 - - - I - - - Belongs to the PlsY family
KMDGHHAD_03171 3.79e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMDGHHAD_03172 4.41e-113 - - - C - - - Flavodoxin
KMDGHHAD_03173 0.0 nrdA 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMDGHHAD_03175 4.43e-26 - - - - - - - -
KMDGHHAD_03176 2.69e-56 - - - L - - - Transposase
KMDGHHAD_03177 0.0 - 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KMDGHHAD_03178 1.19e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
KMDGHHAD_03179 2.96e-72 csoR_2 - - S ko:K21600 - ko00000,ko03000 protein conserved in bacteria
KMDGHHAD_03180 9.01e-11 - - - - - - - -
KMDGHHAD_03181 4.77e-165 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KMDGHHAD_03182 5.73e-170 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KMDGHHAD_03183 1.32e-97 yycN - - K - - - FR47-like protein
KMDGHHAD_03184 6.64e-297 lmrP - - E ko:K08152 - ko00000,ko02000 Transmembrane secretion effector
KMDGHHAD_03185 6.46e-150 - - - E - - - lactoylglutathione lyase activity
KMDGHHAD_03187 3.59e-63 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 GDP-mannose mannosyl hydrolase activity
KMDGHHAD_03189 2.33e-98 - - - - - - - -
KMDGHHAD_03190 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KMDGHHAD_03191 0.0 yfiB - - V ko:K06147 - ko00000,ko02000 ABC transporter
KMDGHHAD_03192 1.99e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KMDGHHAD_03193 5.38e-142 - - - S - - - Haloacid dehalogenase-like hydrolase
KMDGHHAD_03195 2.63e-223 - - - S - - - High confidence in function and specificity
KMDGHHAD_03196 4.85e-167 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMDGHHAD_03197 0.0 ykoH - - T - - - Histidine kinase
KMDGHHAD_03198 3.04e-141 - - - - - - - -
KMDGHHAD_03199 9.23e-84 - - - T - - - ECF transporter, substrate-specific component
KMDGHHAD_03200 5.88e-277 - - - O - - - Peptidase S53
KMDGHHAD_03201 3.94e-49 XK26_06125 - - S - - - Transcriptional Coactivator p15 (PC4)
KMDGHHAD_03203 1.31e-51 - - - D - - - nuclear chromosome segregation
KMDGHHAD_03204 1.57e-128 - - - - - - - -
KMDGHHAD_03205 2.72e-129 - - - - - - - -
KMDGHHAD_03206 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
KMDGHHAD_03207 5.64e-112 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KMDGHHAD_03208 1.07e-151 yttP - - K - - - Transcriptional regulator
KMDGHHAD_03209 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KMDGHHAD_03210 4.8e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KMDGHHAD_03211 9.22e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMDGHHAD_03212 7.27e-38 B4168_3115 - - S ko:K06419 - ko00000 spore protein
KMDGHHAD_03213 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMDGHHAD_03214 1.03e-237 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
KMDGHHAD_03215 1.63e-116 yteJ - - S - - - RDD family
KMDGHHAD_03216 3.02e-152 ytfI - - S - - - Protein of unknown function (DUF2953)
KMDGHHAD_03217 1.39e-96 ytfJ - - S - - - Sporulation protein YtfJ
KMDGHHAD_03218 4.75e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KMDGHHAD_03219 2.71e-235 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KMDGHHAD_03220 1.45e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMDGHHAD_03221 6.19e-201 - - - S - - - EcsC protein family
KMDGHHAD_03222 4.68e-104 uspA - - T - - - Belongs to the universal stress protein A family
KMDGHHAD_03223 7.47e-259 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KMDGHHAD_03224 1.92e-262 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KMDGHHAD_03225 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
KMDGHHAD_03226 1.36e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
KMDGHHAD_03227 5.22e-56 ytpI - - S - - - YtpI-like protein
KMDGHHAD_03228 3.52e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
KMDGHHAD_03229 7.28e-117 ytrI - - - - - - -
KMDGHHAD_03230 1.23e-69 ytrH - - S - - - Sporulation protein YtrH
KMDGHHAD_03231 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KMDGHHAD_03232 1.8e-288 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KMDGHHAD_03233 2.01e-209 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KMDGHHAD_03234 8.01e-228 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KMDGHHAD_03235 5.39e-224 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KMDGHHAD_03236 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KMDGHHAD_03237 2.16e-231 ytvI - - S - - - sporulation integral membrane protein YtvI
KMDGHHAD_03238 1.05e-96 - - - S - - - Membrane
KMDGHHAD_03239 1.08e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KMDGHHAD_03240 2.57e-311 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
KMDGHHAD_03241 1.59e-216 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
KMDGHHAD_03242 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMDGHHAD_03243 6.69e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KMDGHHAD_03244 5.02e-141 ytaF - - P - - - Probably functions as a manganese efflux pump
KMDGHHAD_03245 1.91e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KMDGHHAD_03246 1.66e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMDGHHAD_03247 4.02e-104 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMDGHHAD_03248 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
KMDGHHAD_03249 3.15e-229 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KMDGHHAD_03250 1.15e-197 ytxC - - S - - - YtxC-like family
KMDGHHAD_03251 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMDGHHAD_03252 8.32e-278 - - - G - - - Transmembrane secretion effector
KMDGHHAD_03253 8.37e-145 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KMDGHHAD_03254 4.3e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KMDGHHAD_03255 3.16e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMDGHHAD_03257 1.36e-101 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KMDGHHAD_03258 0.0 - - - M - - - O-Antigen ligase
KMDGHHAD_03259 2.28e-122 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMDGHHAD_03260 5.27e-235 - - - C - - - COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMDGHHAD_03261 1.26e-214 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KMDGHHAD_03262 9.34e-130 - - - S ko:K19784 - ko00000 NAD(P)H-dependent FMN reductase
KMDGHHAD_03263 1.82e-226 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMDGHHAD_03264 2.72e-163 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KMDGHHAD_03265 1.1e-15 - - - S - - - NADPH-dependent FMN reductase
KMDGHHAD_03266 1.01e-73 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
KMDGHHAD_03267 2.03e-154 M1-1017 - - S - - - Protein of unknown function (DUF1129)
KMDGHHAD_03268 7.63e-74 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
KMDGHHAD_03269 8.95e-65 - - - - - - - -
KMDGHHAD_03270 2.18e-180 - - - S - - - Domain of unknown function (DUF4405)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)