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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLKPNGBE_00001	7.35e-85	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HLKPNGBE_00002	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLKPNGBE_00003	2.4e-106	yvbK	-	-	K	-	-	-	acetyltransferase
HLKPNGBE_00004	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HLKPNGBE_00005	2.38e-158	yvbI	-	-	M	-	-	-	Membrane
HLKPNGBE_00006	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
HLKPNGBE_00007	9.68e-136	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HLKPNGBE_00008	1.74e-130	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HLKPNGBE_00009	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLKPNGBE_00010	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLKPNGBE_00011	2.58e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLKPNGBE_00012	1.03e-146	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLKPNGBE_00013	9.63e-60	sdpR	-	-	K	-	-	-	transcriptional
HLKPNGBE_00014	8.32e-133	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HLKPNGBE_00016	4.79e-224	-	-	-	-	-	-	-	-
HLKPNGBE_00017	2.75e-11	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HLKPNGBE_00018	1.15e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HLKPNGBE_00019	6.29e-272	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLKPNGBE_00020	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLKPNGBE_00021	2.89e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLKPNGBE_00022	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLKPNGBE_00023	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_00024	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
HLKPNGBE_00025	1.19e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLKPNGBE_00026	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HLKPNGBE_00027	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
HLKPNGBE_00028	4.03e-196	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
HLKPNGBE_00029	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HLKPNGBE_00030	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HLKPNGBE_00031	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLKPNGBE_00032	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HLKPNGBE_00034	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00035	8.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLKPNGBE_00036	4.28e-72	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HLKPNGBE_00037	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HLKPNGBE_00038	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HLKPNGBE_00039	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLKPNGBE_00040	7.89e-254	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HLKPNGBE_00041	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HLKPNGBE_00042	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
HLKPNGBE_00043	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLKPNGBE_00044	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HLKPNGBE_00045	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
HLKPNGBE_00046	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HLKPNGBE_00047	3.88e-140	yvgT	-	-	S	-	-	-	membrane
HLKPNGBE_00048	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLKPNGBE_00049	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HLKPNGBE_00050	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HLKPNGBE_00051	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HLKPNGBE_00052	7.97e-113	yvgO	-	-	-	-	-	-	-
HLKPNGBE_00053	4.54e-203	yvgN	-	-	S	-	-	-	reductase
HLKPNGBE_00054	6.08e-154	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HLKPNGBE_00055	6.57e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HLKPNGBE_00056	5.58e-218	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HLKPNGBE_00057	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HLKPNGBE_00058	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HLKPNGBE_00059	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HLKPNGBE_00060	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HLKPNGBE_00062	1.14e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLKPNGBE_00063	1.48e-237	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_00064	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_00065	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLKPNGBE_00066	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
HLKPNGBE_00067	1.62e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_00068	1.17e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HLKPNGBE_00069	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HLKPNGBE_00070	1.59e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HLKPNGBE_00071	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
HLKPNGBE_00072	6.74e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HLKPNGBE_00073	5.07e-32	-	-	-	-	-	-	-	-
HLKPNGBE_00074	2.08e-169	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_00075	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HLKPNGBE_00076	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HLKPNGBE_00077	5.21e-182	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00078	5.15e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HLKPNGBE_00079	3.29e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_00080	0.0	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HLKPNGBE_00081	8.21e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HLKPNGBE_00082	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_00083	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HLKPNGBE_00084	4.22e-144	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HLKPNGBE_00085	6.57e-178	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLKPNGBE_00086	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HLKPNGBE_00087	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_00088	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_00089	1.22e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HLKPNGBE_00090	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HLKPNGBE_00091	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HLKPNGBE_00092	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HLKPNGBE_00093	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLKPNGBE_00094	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00095	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_00096	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_00097	9.63e-306	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLKPNGBE_00098	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HLKPNGBE_00099	6.65e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00100	1.21e-41	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HLKPNGBE_00101	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HLKPNGBE_00102	2.01e-87	-	-	-	S	-	-	-	YusW-like protein
HLKPNGBE_00103	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLKPNGBE_00104	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HLKPNGBE_00105	1.52e-206	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HLKPNGBE_00106	4.48e-67	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00107	6.81e-82	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00108	1.76e-86	yusQ	-	-	S	-	-	-	Tautomerase enzyme
HLKPNGBE_00109	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HLKPNGBE_00110	3.83e-99	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HLKPNGBE_00111	2.12e-70	yusN	-	-	M	-	-	-	Coat F domain
HLKPNGBE_00112	2.23e-54	-	-	-	-	-	-	-	-
HLKPNGBE_00113	2.09e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HLKPNGBE_00114	2.86e-14	-	-	-	S	-	-	-	YuzL-like protein
HLKPNGBE_00115	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HLKPNGBE_00116	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HLKPNGBE_00117	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HLKPNGBE_00118	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HLKPNGBE_00119	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HLKPNGBE_00120	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HLKPNGBE_00121	1.32e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HLKPNGBE_00122	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
HLKPNGBE_00123	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HLKPNGBE_00124	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLKPNGBE_00125	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HLKPNGBE_00126	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HLKPNGBE_00127	5.44e-81	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLKPNGBE_00128	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HLKPNGBE_00129	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HLKPNGBE_00130	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLKPNGBE_00131	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HLKPNGBE_00132	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HLKPNGBE_00134	7.94e-22	ydhU	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
HLKPNGBE_00135	1.12e-98	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HLKPNGBE_00136	3.49e-273	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HLKPNGBE_00137	1.93e-244	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLKPNGBE_00138	9.28e-219	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HLKPNGBE_00139	1.9e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HLKPNGBE_00140	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLKPNGBE_00141	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLKPNGBE_00142	6.09e-70	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_00143	7.97e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_00144	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HLKPNGBE_00145	4.01e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HLKPNGBE_00146	1.25e-236	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLKPNGBE_00147	1.43e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_00149	9.93e-91	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HLKPNGBE_00150	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HLKPNGBE_00151	7.71e-166	-	-	-	-	-	-	-	-
HLKPNGBE_00152	9.61e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLKPNGBE_00153	8.92e-310	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HLKPNGBE_00154	5.24e-158	ydhC	-	-	K	-	-	-	FCD
HLKPNGBE_00155	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLKPNGBE_00156	5.97e-267	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HLKPNGBE_00157	1.15e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HLKPNGBE_00158	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
HLKPNGBE_00159	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HLKPNGBE_00160	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_00161	5.09e-119	-	-	-	S	-	-	-	DinB family
HLKPNGBE_00162	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_00163	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HLKPNGBE_00164	2.49e-114	yycN	-	-	K	-	-	-	Acetyltransferase
HLKPNGBE_00165	4.21e-72	-	-	-	S	-	-	-	DoxX-like family
HLKPNGBE_00166	7.86e-132	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLKPNGBE_00167	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HLKPNGBE_00168	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HLKPNGBE_00169	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLKPNGBE_00170	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLKPNGBE_00171	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLKPNGBE_00173	5.33e-39	-	-	-	-	-	-	-	-
HLKPNGBE_00174	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HLKPNGBE_00175	9.63e-77	ydfQ	-	-	CO	-	-	-	Thioredoxin
HLKPNGBE_00176	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HLKPNGBE_00177	9.49e-239	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HLKPNGBE_00178	3.45e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HLKPNGBE_00179	3.15e-200	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLKPNGBE_00180	2.13e-189	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HLKPNGBE_00181	6.79e-152	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HLKPNGBE_00182	9.73e-226	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLKPNGBE_00183	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HLKPNGBE_00184	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_00185	4.11e-253	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_00187	1.37e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLKPNGBE_00188	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLKPNGBE_00189	5.97e-151	ydfE	-	-	S	-	-	-	Flavin reductase like domain
HLKPNGBE_00190	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLKPNGBE_00191	3.05e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_00192	8.05e-191	-	-	-	J	-	-	-	GNAT acetyltransferase
HLKPNGBE_00193	9.07e-297	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLKPNGBE_00194	2.56e-76	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HLKPNGBE_00195	3.74e-136	ydeS	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00196	1.51e-261	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HLKPNGBE_00197	2.44e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
HLKPNGBE_00198	5.03e-91	ydeP	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00199	1.68e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLKPNGBE_00200	1.33e-77	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLKPNGBE_00201	8.6e-138	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HLKPNGBE_00202	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HLKPNGBE_00203	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLKPNGBE_00204	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
HLKPNGBE_00205	6.11e-150	-	-	-	-	-	-	-	-
HLKPNGBE_00206	1.26e-138	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HLKPNGBE_00207	4.76e-72	ydeH	-	-	-	-	-	-	-
HLKPNGBE_00208	1.19e-280	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HLKPNGBE_00209	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLKPNGBE_00210	2.87e-213	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HLKPNGBE_00211	4.99e-224	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLKPNGBE_00212	3.23e-215	-	-	-	K	-	-	-	AraC-like ligand binding domain
HLKPNGBE_00213	2.47e-47	ydzE	-	-	EG	-	-	-	spore germination
HLKPNGBE_00214	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HLKPNGBE_00215	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HLKPNGBE_00216	4.24e-146	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
HLKPNGBE_00218	6.38e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLKPNGBE_00219	1.19e-101	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLKPNGBE_00220	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLKPNGBE_00221	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HLKPNGBE_00223	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
HLKPNGBE_00224	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HLKPNGBE_00225	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLKPNGBE_00226	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HLKPNGBE_00227	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLKPNGBE_00228	5.23e-205	yybS	-	-	S	-	-	-	membrane
HLKPNGBE_00230	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HLKPNGBE_00231	6.68e-90	yybR	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00232	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HLKPNGBE_00233	2.34e-92	-	-	-	-	-	-	-	-
HLKPNGBE_00235	6.8e-308	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_00236	3.44e-22	-	-	-	-	-	-	-	-
HLKPNGBE_00237	1.61e-102	yybN	-	-	S	-	-	-	Protein of unknown function (DUF2712)
HLKPNGBE_00238	3.78e-169	-	-	-	-	-	-	-	-
HLKPNGBE_00239	5.36e-157	-	-	-	-	-	-	-	-
HLKPNGBE_00240	2.34e-163	-	-	-	S	-	-	-	Protein of unknown function (DUF2705)
HLKPNGBE_00241	1.14e-149	yybJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLKPNGBE_00242	4.35e-194	-	-	-	-	-	-	-	-
HLKPNGBE_00243	3.02e-88	-	-	-	S	-	-	-	SnoaL-like domain
HLKPNGBE_00244	1.46e-164	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
HLKPNGBE_00245	3.31e-281	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_00246	1.36e-212	yybE	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00247	7.91e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_00248	1.27e-99	yybC	-	-	-	-	-	-	-
HLKPNGBE_00249	5.29e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLKPNGBE_00250	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
HLKPNGBE_00251	2.45e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_00252	8.73e-132	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HLKPNGBE_00253	4.03e-130	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HLKPNGBE_00254	1.09e-87	-	-	-	S	-	-	-	YjbR
HLKPNGBE_00255	2.2e-139	yyaP	-	-	H	-	-	-	RibD C-terminal domain
HLKPNGBE_00256	0.0	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_00257	1.46e-58	yyaL	-	-	O	ko:K06888	-	ko00000	Highly conserved protein containing a thioredoxin domain
HLKPNGBE_00258	1.34e-88	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HLKPNGBE_00259	1.99e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_00260	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HLKPNGBE_00261	8.91e-217	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLKPNGBE_00262	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
HLKPNGBE_00263	1.14e-130	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HLKPNGBE_00264	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLKPNGBE_00265	3.03e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00266	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLKPNGBE_00267	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLKPNGBE_00268	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLKPNGBE_00269	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLKPNGBE_00270	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLKPNGBE_00271	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLKPNGBE_00272	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00273	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
HLKPNGBE_00274	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HLKPNGBE_00275	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLKPNGBE_00276	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HLKPNGBE_00277	1.13e-98	-	-	-	S	-	-	-	Bacterial PH domain
HLKPNGBE_00278	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HLKPNGBE_00279	8.68e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HLKPNGBE_00280	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLKPNGBE_00281	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLKPNGBE_00282	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HLKPNGBE_00283	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLKPNGBE_00284	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLKPNGBE_00285	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLKPNGBE_00286	1.71e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLKPNGBE_00287	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HLKPNGBE_00288	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLKPNGBE_00289	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HLKPNGBE_00290	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLKPNGBE_00291	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLKPNGBE_00292	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HLKPNGBE_00293	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HLKPNGBE_00294	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
HLKPNGBE_00295	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HLKPNGBE_00296	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HLKPNGBE_00297	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HLKPNGBE_00298	2.14e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HLKPNGBE_00299	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLKPNGBE_00300	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLKPNGBE_00301	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLKPNGBE_00302	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLKPNGBE_00303	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLKPNGBE_00304	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLKPNGBE_00305	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLKPNGBE_00306	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLKPNGBE_00307	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLKPNGBE_00308	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLKPNGBE_00309	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HLKPNGBE_00310	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLKPNGBE_00311	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HLKPNGBE_00312	6.17e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLKPNGBE_00313	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLKPNGBE_00314	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HLKPNGBE_00315	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HLKPNGBE_00316	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLKPNGBE_00317	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLKPNGBE_00318	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLKPNGBE_00319	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLKPNGBE_00320	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLKPNGBE_00321	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLKPNGBE_00322	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLKPNGBE_00323	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLKPNGBE_00324	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLKPNGBE_00325	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLKPNGBE_00326	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLKPNGBE_00327	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLKPNGBE_00328	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLKPNGBE_00329	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLKPNGBE_00330	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLKPNGBE_00331	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLKPNGBE_00332	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLKPNGBE_00333	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLKPNGBE_00334	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLKPNGBE_00335	8.78e-238	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HLKPNGBE_00336	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLKPNGBE_00337	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLKPNGBE_00338	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLKPNGBE_00339	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLKPNGBE_00340	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HLKPNGBE_00341	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLKPNGBE_00342	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLKPNGBE_00343	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HLKPNGBE_00344	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLKPNGBE_00345	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLKPNGBE_00346	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLKPNGBE_00347	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLKPNGBE_00348	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLKPNGBE_00349	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLKPNGBE_00350	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HLKPNGBE_00351	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HLKPNGBE_00352	4.29e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLKPNGBE_00353	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLKPNGBE_00354	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLKPNGBE_00355	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HLKPNGBE_00356	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLKPNGBE_00357	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HLKPNGBE_00358	1.82e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HLKPNGBE_00359	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HLKPNGBE_00360	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HLKPNGBE_00361	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLKPNGBE_00362	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HLKPNGBE_00363	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HLKPNGBE_00364	2.76e-65	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HLKPNGBE_00365	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HLKPNGBE_00366	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_00367	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_00368	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00369	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00370	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HLKPNGBE_00371	2.42e-281	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLKPNGBE_00372	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HLKPNGBE_00373	1.5e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HLKPNGBE_00374	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLKPNGBE_00375	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HLKPNGBE_00377	3.03e-239	-	-	-	S	-	-	-	aspartate phosphatase
HLKPNGBE_00378	3.84e-113	yycN	-	-	K	-	-	-	Acetyltransferase
HLKPNGBE_00379	1.68e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HLKPNGBE_00380	1.77e-281	yycP	-	-	-	-	-	-	-
HLKPNGBE_00381	1.7e-45	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HLKPNGBE_00383	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLKPNGBE_00384	1.25e-93	-	-	-	-	-	-	-	-
HLKPNGBE_00386	1.23e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLKPNGBE_00387	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLKPNGBE_00388	7.17e-86	-	-	-	-	-	-	-	-
HLKPNGBE_00389	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HLKPNGBE_00390	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HLKPNGBE_00391	1.99e-17	-	-	-	-	-	-	-	-
HLKPNGBE_00392	1.35e-237	-	-	-	S	-	-	-	Radical SAM superfamily
HLKPNGBE_00393	1.55e-173	-	-	-	O	ko:K16922	-	ko00000,ko01002	Peptidase M50
HLKPNGBE_00394	5.06e-144	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLKPNGBE_00395	4.04e-154	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HLKPNGBE_00396	1.44e-24	-	-	-	-	-	-	-	-
HLKPNGBE_00397	6.34e-165	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_00398	6.69e-47	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HLKPNGBE_00399	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLKPNGBE_00400	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HLKPNGBE_00401	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HLKPNGBE_00402	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLKPNGBE_00403	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HLKPNGBE_00404	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLKPNGBE_00405	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
HLKPNGBE_00406	2.54e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLKPNGBE_00407	1.79e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HLKPNGBE_00408	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HLKPNGBE_00409	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HLKPNGBE_00410	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_00411	4.48e-257	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00412	9.61e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HLKPNGBE_00413	9.33e-254	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
HLKPNGBE_00414	2.88e-290	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HLKPNGBE_00415	2.83e-99	yxaI	-	-	S	-	-	-	membrane protein domain
HLKPNGBE_00416	1.43e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HLKPNGBE_00417	2.63e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
HLKPNGBE_00418	1.8e-271	yxaM	-	-	U	-	-	-	MFS_1 like family
HLKPNGBE_00419	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLKPNGBE_00420	8.99e-114	yxnB	-	-	-	-	-	-	-
HLKPNGBE_00421	3.65e-59	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HLKPNGBE_00422	1.29e-177	yxbB	-	-	Q	-	-	-	Met-10+ like-protein
HLKPNGBE_00423	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HLKPNGBE_00424	3.28e-133	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HLKPNGBE_00425	5.05e-260	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HLKPNGBE_00426	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HLKPNGBE_00427	2.82e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLKPNGBE_00428	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00429	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HLKPNGBE_00430	2.42e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLKPNGBE_00431	1.1e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HLKPNGBE_00432	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HLKPNGBE_00433	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HLKPNGBE_00434	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HLKPNGBE_00435	7.26e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLKPNGBE_00436	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HLKPNGBE_00437	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLKPNGBE_00438	5.05e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HLKPNGBE_00439	1.91e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
HLKPNGBE_00440	1.05e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLKPNGBE_00441	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLKPNGBE_00442	6.69e-200	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HLKPNGBE_00443	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00444	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HLKPNGBE_00445	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLKPNGBE_00446	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HLKPNGBE_00447	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HLKPNGBE_00448	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HLKPNGBE_00449	9e-310	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLKPNGBE_00450	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLKPNGBE_00451	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HLKPNGBE_00452	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLKPNGBE_00453	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HLKPNGBE_00454	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLKPNGBE_00455	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HLKPNGBE_00456	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLKPNGBE_00457	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HLKPNGBE_00458	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HLKPNGBE_00459	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HLKPNGBE_00460	2.21e-139	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HLKPNGBE_00461	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HLKPNGBE_00462	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HLKPNGBE_00465	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HLKPNGBE_00466	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HLKPNGBE_00467	1.25e-238	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLKPNGBE_00468	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLKPNGBE_00469	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLKPNGBE_00470	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLKPNGBE_00471	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HLKPNGBE_00472	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLKPNGBE_00473	6.68e-196	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HLKPNGBE_00474	3.77e-218	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLKPNGBE_00475	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLKPNGBE_00476	1.03e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HLKPNGBE_00477	2.27e-216	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HLKPNGBE_00478	3.32e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLKPNGBE_00479	2.78e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLKPNGBE_00480	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLKPNGBE_00481	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
HLKPNGBE_00482	7.88e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLKPNGBE_00483	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLKPNGBE_00486	4.41e-270	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLKPNGBE_00487	1.41e-119	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HLKPNGBE_00488	1.91e-81	-	-	-	K	-	-	-	Transcriptional
HLKPNGBE_00489	8.96e-24	-	-	-	-	-	-	-	-
HLKPNGBE_00490	9.52e-56	-	-	-	-	-	-	-	-
HLKPNGBE_00492	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
HLKPNGBE_00493	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
HLKPNGBE_00494	2.62e-263	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HLKPNGBE_00497	1.38e-43	yddA	-	-	-	-	-	-	-
HLKPNGBE_00498	7.65e-232	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
HLKPNGBE_00499	3.41e-54	yddC	-	-	-	-	-	-	-
HLKPNGBE_00500	7.8e-124	yddD	-	-	S	-	-	-	TcpE family
HLKPNGBE_00501	0.0	yddE	-	-	S	-	-	-	AAA-like domain
HLKPNGBE_00502	2.81e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
HLKPNGBE_00503	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
HLKPNGBE_00504	4.74e-243	yddH	-	-	M	-	-	-	Lysozyme-like
HLKPNGBE_00505	4.05e-114	yddI	-	-	-	-	-	-	-
HLKPNGBE_00506	6.67e-86	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HLKPNGBE_00507	8.08e-192	-	-	-	S	-	-	-	TIR domain
HLKPNGBE_00508	5.17e-92	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HLKPNGBE_00510	2.93e-212	-	-	-	-	-	-	-	-
HLKPNGBE_00511	2.43e-241	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_00512	8.15e-94	lrpA	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
HLKPNGBE_00513	2.17e-102	lrpB	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	transcriptional
HLKPNGBE_00514	1.62e-128	yddQ	-	-	Q	-	-	-	Isochorismatase family
HLKPNGBE_00515	1.34e-184	yddR	-	-	S	-	-	-	Zn-dependent hydrolases of the beta-lactamase fold
HLKPNGBE_00516	3.35e-288	ydeG3	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLKPNGBE_00518	4.5e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
HLKPNGBE_00519	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HLKPNGBE_00520	2.81e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLKPNGBE_00521	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HLKPNGBE_00522	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HLKPNGBE_00523	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLKPNGBE_00525	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HLKPNGBE_00526	2.43e-150	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HLKPNGBE_00527	7.7e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HLKPNGBE_00528	1.44e-127	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HLKPNGBE_00529	1.55e-110	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLKPNGBE_00530	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLKPNGBE_00531	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLKPNGBE_00532	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLKPNGBE_00533	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HLKPNGBE_00534	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HLKPNGBE_00535	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_00540	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
HLKPNGBE_00541	3.88e-37	-	-	-	-	-	-	-	-
HLKPNGBE_00542	6.95e-173	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HLKPNGBE_00543	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HLKPNGBE_00544	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
HLKPNGBE_00546	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HLKPNGBE_00547	4.15e-185	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HLKPNGBE_00548	1.78e-219	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HLKPNGBE_00549	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLKPNGBE_00550	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HLKPNGBE_00552	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLKPNGBE_00553	2.79e-102	ygaO	-	-	-	-	-	-	-
HLKPNGBE_00554	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_00556	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
HLKPNGBE_00557	5.09e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLKPNGBE_00558	4.79e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
HLKPNGBE_00559	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLKPNGBE_00560	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HLKPNGBE_00561	2.29e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HLKPNGBE_00562	4.08e-110	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HLKPNGBE_00563	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HLKPNGBE_00564	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HLKPNGBE_00565	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HLKPNGBE_00566	3.8e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HLKPNGBE_00567	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HLKPNGBE_00568	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
HLKPNGBE_00569	3.95e-59	yhcC	-	-	-	-	-	-	-
HLKPNGBE_00570	2.92e-69	-	-	-	-	-	-	-	-
HLKPNGBE_00571	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_00572	3.38e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_00573	6.47e-213	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_00574	3.45e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLKPNGBE_00575	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HLKPNGBE_00576	1.34e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLKPNGBE_00577	2.47e-251	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HLKPNGBE_00578	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLKPNGBE_00579	3.23e-80	yhcM	-	-	-	-	-	-	-
HLKPNGBE_00580	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLKPNGBE_00581	3.96e-227	yhcP	-	-	-	-	-	-	-
HLKPNGBE_00582	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
HLKPNGBE_00583	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLKPNGBE_00584	3.9e-138	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HLKPNGBE_00585	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLKPNGBE_00586	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HLKPNGBE_00587	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HLKPNGBE_00588	3.04e-155	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HLKPNGBE_00589	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLKPNGBE_00590	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLKPNGBE_00591	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HLKPNGBE_00592	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLKPNGBE_00593	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLKPNGBE_00594	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HLKPNGBE_00595	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HLKPNGBE_00596	2.29e-273	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_00597	5.68e-148	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_00598	5.68e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HLKPNGBE_00599	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HLKPNGBE_00600	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HLKPNGBE_00601	2.4e-275	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HLKPNGBE_00602	1.37e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HLKPNGBE_00603	5.29e-307	ygxB	-	-	M	-	-	-	Conserved TM helix
HLKPNGBE_00604	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HLKPNGBE_00605	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HLKPNGBE_00606	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HLKPNGBE_00607	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_00608	5.51e-263	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HLKPNGBE_00609	1.41e-208	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_00610	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HLKPNGBE_00611	4.29e-310	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLKPNGBE_00612	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLKPNGBE_00613	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_00614	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HLKPNGBE_00615	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HLKPNGBE_00616	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_00617	6.74e-244	yhdN	-	-	C	-	-	-	Aldo keto reductase
HLKPNGBE_00618	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLKPNGBE_00619	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLKPNGBE_00620	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HLKPNGBE_00621	4.37e-285	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HLKPNGBE_00622	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLKPNGBE_00623	2.69e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLKPNGBE_00624	1.01e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLKPNGBE_00625	5.44e-174	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HLKPNGBE_00626	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HLKPNGBE_00627	4.51e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HLKPNGBE_00628	2.93e-180	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HLKPNGBE_00629	5.7e-200	nodB1	-	-	G	-	-	-	deacetylase
HLKPNGBE_00630	2.23e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HLKPNGBE_00631	3.94e-307	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HLKPNGBE_00632	3.85e-109	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLKPNGBE_00633	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLKPNGBE_00634	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLKPNGBE_00635	3.31e-143	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HLKPNGBE_00636	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HLKPNGBE_00637	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HLKPNGBE_00638	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HLKPNGBE_00639	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HLKPNGBE_00640	1.51e-261	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HLKPNGBE_00641	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HLKPNGBE_00642	6.69e-264	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HLKPNGBE_00643	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLKPNGBE_00644	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HLKPNGBE_00645	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HLKPNGBE_00646	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HLKPNGBE_00648	1.6e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HLKPNGBE_00649	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
HLKPNGBE_00650	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_00651	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HLKPNGBE_00652	9.85e-303	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HLKPNGBE_00653	0.0	yhaN	-	-	L	-	-	-	AAA domain
HLKPNGBE_00654	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HLKPNGBE_00655	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HLKPNGBE_00656	2.29e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLKPNGBE_00657	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HLKPNGBE_00658	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HLKPNGBE_00659	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HLKPNGBE_00660	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HLKPNGBE_00661	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HLKPNGBE_00662	1.84e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLKPNGBE_00663	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HLKPNGBE_00664	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HLKPNGBE_00665	3.11e-272	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLKPNGBE_00666	5e-162	ecsC	-	-	S	-	-	-	EcsC protein family
HLKPNGBE_00667	4.8e-295	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HLKPNGBE_00668	8.98e-317	yhfA	-	-	C	-	-	-	membrane
HLKPNGBE_00669	1.33e-23	-	-	-	C	-	-	-	Rubrerythrin
HLKPNGBE_00670	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HLKPNGBE_00671	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLKPNGBE_00672	7.78e-261	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HLKPNGBE_00673	2.06e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HLKPNGBE_00674	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HLKPNGBE_00675	3.49e-133	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_00676	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HLKPNGBE_00677	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLKPNGBE_00678	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HLKPNGBE_00679	2.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
HLKPNGBE_00680	3.75e-94	-	-	-	S	-	-	-	ASCH
HLKPNGBE_00681	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLKPNGBE_00682	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HLKPNGBE_00683	1.21e-246	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HLKPNGBE_00684	1.82e-144	yhfK	-	-	GM	-	-	-	NmrA-like family
HLKPNGBE_00685	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HLKPNGBE_00686	2.78e-85	yhfM	-	-	-	-	-	-	-
HLKPNGBE_00687	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
HLKPNGBE_00688	2.94e-261	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLKPNGBE_00689	2.75e-105	-	-	-	K	-	-	-	acetyltransferase
HLKPNGBE_00690	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HLKPNGBE_00691	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HLKPNGBE_00692	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HLKPNGBE_00693	1.19e-256	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLKPNGBE_00694	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HLKPNGBE_00695	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HLKPNGBE_00696	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HLKPNGBE_00697	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HLKPNGBE_00698	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_00699	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
HLKPNGBE_00700	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HLKPNGBE_00701	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLKPNGBE_00702	5e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HLKPNGBE_00703	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLKPNGBE_00704	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HLKPNGBE_00705	2.57e-78	yhjD	-	-	-	-	-	-	-
HLKPNGBE_00706	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HLKPNGBE_00707	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLKPNGBE_00708	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HLKPNGBE_00709	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_00710	3.12e-273	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HLKPNGBE_00711	3.98e-257	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HLKPNGBE_00712	2.63e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLKPNGBE_00713	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HLKPNGBE_00714	2.63e-240	yhjM	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00715	2.14e-260	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HLKPNGBE_00716	1.27e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HLKPNGBE_00717	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
HLKPNGBE_00718	3.54e-77	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
HLKPNGBE_00719	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
HLKPNGBE_00720	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HLKPNGBE_00721	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HLKPNGBE_00722	1.2e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLKPNGBE_00723	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HLKPNGBE_00724	1.34e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HLKPNGBE_00725	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HLKPNGBE_00726	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HLKPNGBE_00727	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HLKPNGBE_00728	8.23e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HLKPNGBE_00729	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HLKPNGBE_00730	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HLKPNGBE_00731	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HLKPNGBE_00732	3.96e-224	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HLKPNGBE_00733	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HLKPNGBE_00734	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
HLKPNGBE_00735	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLKPNGBE_00736	7.48e-137	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HLKPNGBE_00737	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLKPNGBE_00738	1.85e-115	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
HLKPNGBE_00739	6.82e-193	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HLKPNGBE_00740	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
HLKPNGBE_00741	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_00742	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLKPNGBE_00743	9.72e-254	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HLKPNGBE_00744	7.28e-122	yisT	-	-	S	-	-	-	DinB family
HLKPNGBE_00745	5.42e-140	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HLKPNGBE_00746	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLKPNGBE_00747	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HLKPNGBE_00748	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLKPNGBE_00749	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HLKPNGBE_00750	1.37e-295	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HLKPNGBE_00751	9.51e-185	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HLKPNGBE_00752	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
HLKPNGBE_00753	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
HLKPNGBE_00754	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLKPNGBE_00755	2.14e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HLKPNGBE_00756	1.01e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_00757	7.86e-207	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_00758	8.19e-107	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_00759	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HLKPNGBE_00760	1.06e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HLKPNGBE_00761	1.94e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HLKPNGBE_00762	4.16e-122	-	-	-	-	-	-	-	-
HLKPNGBE_00763	1.42e-218	-	-	-	-	-	-	-	-
HLKPNGBE_00764	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HLKPNGBE_00765	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HLKPNGBE_00766	7.76e-123	-	-	-	-	-	-	-	-
HLKPNGBE_00767	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
HLKPNGBE_00768	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HLKPNGBE_00769	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00770	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLKPNGBE_00771	1.61e-92	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HLKPNGBE_00772	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HLKPNGBE_00773	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HLKPNGBE_00774	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HLKPNGBE_00775	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HLKPNGBE_00776	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
HLKPNGBE_00777	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HLKPNGBE_00778	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HLKPNGBE_00779	9.02e-256	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLKPNGBE_00780	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLKPNGBE_00781	5.4e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HLKPNGBE_00782	1.69e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HLKPNGBE_00783	1.4e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLKPNGBE_00784	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HLKPNGBE_00785	3.66e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLKPNGBE_00786	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HLKPNGBE_00787	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLKPNGBE_00788	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HLKPNGBE_00789	5.41e-134	yjaV	-	-	-	-	-	-	-
HLKPNGBE_00790	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HLKPNGBE_00791	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HLKPNGBE_00792	2.67e-38	yjzB	-	-	-	-	-	-	-
HLKPNGBE_00793	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLKPNGBE_00794	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLKPNGBE_00795	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HLKPNGBE_00796	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_00797	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_00798	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HLKPNGBE_00799	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLKPNGBE_00800	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLKPNGBE_00801	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HLKPNGBE_00802	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HLKPNGBE_00803	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLKPNGBE_00804	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLKPNGBE_00805	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLKPNGBE_00806	1.37e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_00807	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_00808	3.98e-248	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLKPNGBE_00809	2.65e-133	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_00810	3.51e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLKPNGBE_00811	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HLKPNGBE_00812	6.89e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLKPNGBE_00813	1.31e-283	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HLKPNGBE_00814	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HLKPNGBE_00815	2.68e-28	-	-	-	-	-	-	-	-
HLKPNGBE_00817	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HLKPNGBE_00818	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HLKPNGBE_00819	3.42e-127	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLKPNGBE_00820	5.15e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_00821	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HLKPNGBE_00822	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HLKPNGBE_00823	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLKPNGBE_00824	9.4e-206	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLKPNGBE_00825	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HLKPNGBE_00826	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLKPNGBE_00827	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HLKPNGBE_00828	4.01e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HLKPNGBE_00829	1.14e-277	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HLKPNGBE_00830	5.35e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HLKPNGBE_00831	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HLKPNGBE_00832	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLKPNGBE_00833	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLKPNGBE_00834	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HLKPNGBE_00835	2.32e-107	yjbX	-	-	S	-	-	-	Spore coat protein
HLKPNGBE_00836	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HLKPNGBE_00837	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HLKPNGBE_00838	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HLKPNGBE_00839	1.08e-54	cotW	-	-	-	ko:K06341	-	ko00000	-
HLKPNGBE_00840	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HLKPNGBE_00841	3.03e-76	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HLKPNGBE_00844	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HLKPNGBE_00845	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLKPNGBE_00846	6.31e-51	-	-	-	-	-	-	-	-
HLKPNGBE_00847	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_00848	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HLKPNGBE_00849	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HLKPNGBE_00850	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLKPNGBE_00851	6.4e-281	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLKPNGBE_00852	2.13e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HLKPNGBE_00853	2.58e-274	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
HLKPNGBE_00856	3.75e-269	-	-	-	S	-	-	-	Putative amidase domain
HLKPNGBE_00857	1.52e-68	yjcN	-	-	-	-	-	-	-
HLKPNGBE_00860	2.24e-106	-	-	-	L	-	-	-	Transposase
HLKPNGBE_00861	5.68e-100	yjcP	-	-	-	-	-	-	-
HLKPNGBE_00862	1.01e-65	-	-	-	S	-	-	-	YjcQ protein
HLKPNGBE_00863	3.29e-121	yqaS	-	-	L	-	-	-	DNA packaging
HLKPNGBE_00864	3.8e-63	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HLKPNGBE_00865	3.42e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLKPNGBE_00866	0.000759	-	-	-	-	-	-	-	-
HLKPNGBE_00867	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HLKPNGBE_00868	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_00869	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLKPNGBE_00870	4.79e-78	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HLKPNGBE_00871	1.36e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLKPNGBE_00873	1.01e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLKPNGBE_00874	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HLKPNGBE_00875	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HLKPNGBE_00876	5.31e-224	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLKPNGBE_00878	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HLKPNGBE_00879	2.22e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
HLKPNGBE_00880	1.95e-30	yjfB	-	-	S	-	-	-	Putative motility protein
HLKPNGBE_00881	3.24e-219	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HLKPNGBE_00882	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HLKPNGBE_00883	1.22e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HLKPNGBE_00884	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HLKPNGBE_00885	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HLKPNGBE_00887	1.91e-149	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HLKPNGBE_00889	1.48e-289	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLKPNGBE_00890	8.74e-280	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLKPNGBE_00891	1.11e-41	-	-	-	-	-	-	-	-
HLKPNGBE_00892	8.69e-189	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HLKPNGBE_00893	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HLKPNGBE_00894	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLKPNGBE_00895	1.09e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HLKPNGBE_00896	8.91e-121	yjlB	-	-	S	-	-	-	Cupin domain
HLKPNGBE_00897	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HLKPNGBE_00898	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLKPNGBE_00899	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HLKPNGBE_00900	6.34e-316	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HLKPNGBE_00901	2.02e-248	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HLKPNGBE_00902	1.6e-246	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HLKPNGBE_00903	1.66e-274	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HLKPNGBE_00904	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_00905	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
HLKPNGBE_00906	6.95e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HLKPNGBE_00907	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HLKPNGBE_00908	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HLKPNGBE_00909	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLKPNGBE_00910	4.87e-106	yjoA	-	-	S	-	-	-	DinB family
HLKPNGBE_00911	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
HLKPNGBE_00912	1.6e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HLKPNGBE_00914	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
HLKPNGBE_00915	1.37e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HLKPNGBE_00916	3.31e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
HLKPNGBE_00917	1.47e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
HLKPNGBE_00918	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HLKPNGBE_00919	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HLKPNGBE_00920	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLKPNGBE_00922	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HLKPNGBE_00923	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HLKPNGBE_00927	5.95e-112	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HLKPNGBE_00928	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HLKPNGBE_00929	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HLKPNGBE_00930	0.0	yqbA	-	-	S	-	-	-	portal protein
HLKPNGBE_00931	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HLKPNGBE_00932	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
HLKPNGBE_00933	2.06e-85	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HLKPNGBE_00934	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HLKPNGBE_00935	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HLKPNGBE_00936	2.87e-101	xkdJ	-	-	-	-	-	-	-
HLKPNGBE_00937	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HLKPNGBE_00938	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HLKPNGBE_00939	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HLKPNGBE_00940	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HLKPNGBE_00941	1.77e-158	xkdP	-	-	S	-	-	-	Lysin motif
HLKPNGBE_00942	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
HLKPNGBE_00943	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HLKPNGBE_00944	1.97e-92	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HLKPNGBE_00945	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HLKPNGBE_00946	9.63e-136	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HLKPNGBE_00947	4.43e-56	-	-	-	-	-	-	-	-
HLKPNGBE_00948	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_00949	8.68e-74	xkdW	-	-	S	-	-	-	XkdW protein
HLKPNGBE_00950	9.34e-33	xkdX	-	-	-	-	-	-	-
HLKPNGBE_00951	1.51e-198	xepA	-	-	-	-	-	-	-
HLKPNGBE_00952	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HLKPNGBE_00953	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
HLKPNGBE_00954	5.76e-212	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HLKPNGBE_00955	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HLKPNGBE_00956	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HLKPNGBE_00957	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HLKPNGBE_00958	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HLKPNGBE_00959	7.7e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HLKPNGBE_00960	3.43e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HLKPNGBE_00962	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLKPNGBE_00963	1.34e-230	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLKPNGBE_00965	6.72e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLKPNGBE_00966	1.54e-183	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
HLKPNGBE_00967	2.42e-197	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HLKPNGBE_00968	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLKPNGBE_00969	6.35e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLKPNGBE_00970	6.22e-242	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_00971	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLKPNGBE_00973	4.26e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HLKPNGBE_00974	1.24e-259	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HLKPNGBE_00975	2.56e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLKPNGBE_00976	1.77e-238	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_00977	9.83e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HLKPNGBE_00978	4.37e-206	ykgA	-	-	E	-	-	-	Amidinotransferase
HLKPNGBE_00979	3.82e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HLKPNGBE_00980	2.65e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HLKPNGBE_00981	5.85e-13	-	-	-	-	-	-	-	-
HLKPNGBE_00982	4.81e-168	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLKPNGBE_00983	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HLKPNGBE_00984	3.59e-128	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLKPNGBE_00985	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HLKPNGBE_00986	2.86e-68	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HLKPNGBE_00987	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HLKPNGBE_00988	3.16e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLKPNGBE_00989	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLKPNGBE_00990	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HLKPNGBE_00991	1.21e-98	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HLKPNGBE_00992	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HLKPNGBE_00994	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
HLKPNGBE_00995	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLKPNGBE_00996	3.66e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLKPNGBE_00997	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLKPNGBE_00998	3.8e-175	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLKPNGBE_00999	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_01000	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLKPNGBE_01001	7.28e-144	ykoF	-	-	S	-	-	-	YKOF-related Family
HLKPNGBE_01002	1.28e-160	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_01003	8.05e-312	ykoH	-	-	T	-	-	-	Histidine kinase
HLKPNGBE_01004	3.35e-146	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLKPNGBE_01005	2.24e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLKPNGBE_01006	1.45e-08	-	-	-	-	-	-	-	-
HLKPNGBE_01008	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HLKPNGBE_01009	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
HLKPNGBE_01010	1.63e-25	-	-	-	-	-	-	-	-
HLKPNGBE_01011	3.04e-36	ykoL	-	-	-	-	-	-	-
HLKPNGBE_01012	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HLKPNGBE_01013	1.19e-281	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HLKPNGBE_01014	2.48e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HLKPNGBE_01015	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HLKPNGBE_01016	0.0	ykoS	-	-	-	-	-	-	-
HLKPNGBE_01017	5.72e-239	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLKPNGBE_01018	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HLKPNGBE_01019	7.55e-206	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HLKPNGBE_01020	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HLKPNGBE_01021	4.48e-153	ykoX	-	-	S	-	-	-	membrane-associated protein
HLKPNGBE_01022	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HLKPNGBE_01023	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_01024	9.33e-219	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HLKPNGBE_01025	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HLKPNGBE_01026	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HLKPNGBE_01027	3.4e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLKPNGBE_01028	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HLKPNGBE_01030	8.33e-31	ykzE	-	-	-	-	-	-	-
HLKPNGBE_01031	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HLKPNGBE_01032	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_01033	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLKPNGBE_01035	1.62e-253	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HLKPNGBE_01036	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HLKPNGBE_01037	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLKPNGBE_01038	4.81e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLKPNGBE_01039	3.39e-295	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HLKPNGBE_01040	1.07e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HLKPNGBE_01041	4.52e-147	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HLKPNGBE_01042	1.5e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HLKPNGBE_01043	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HLKPNGBE_01045	5.84e-95	eag	-	-	-	-	-	-	-
HLKPNGBE_01046	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HLKPNGBE_01047	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HLKPNGBE_01048	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HLKPNGBE_01049	3.23e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HLKPNGBE_01050	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HLKPNGBE_01051	4.26e-230	ykvI	-	-	S	-	-	-	membrane
HLKPNGBE_01052	1.11e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HLKPNGBE_01053	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HLKPNGBE_01054	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HLKPNGBE_01055	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HLKPNGBE_01056	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_01057	9.35e-173	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLKPNGBE_01058	2.69e-275	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLKPNGBE_01059	1.85e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
HLKPNGBE_01060	2.5e-169	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HLKPNGBE_01061	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HLKPNGBE_01062	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01063	2.6e-39	-	-	-	-	-	-	-	-
HLKPNGBE_01064	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HLKPNGBE_01065	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLKPNGBE_01066	5.79e-117	stoA	-	-	CO	-	-	-	thiol-disulfide
HLKPNGBE_01067	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HLKPNGBE_01068	3.99e-09	-	-	-	-	-	-	-	-
HLKPNGBE_01069	7.85e-266	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HLKPNGBE_01071	3.28e-230	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_01073	3.41e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HLKPNGBE_01074	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_01075	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HLKPNGBE_01076	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLKPNGBE_01077	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_01078	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HLKPNGBE_01079	5.49e-170	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_01080	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_01081	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HLKPNGBE_01082	5.36e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HLKPNGBE_01083	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLKPNGBE_01084	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_01085	5.32e-286	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLKPNGBE_01086	1.05e-22	-	-	-	-	-	-	-	-
HLKPNGBE_01087	4.24e-217	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HLKPNGBE_01088	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
HLKPNGBE_01089	8.89e-306	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_01090	7.1e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01091	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HLKPNGBE_01092	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_01093	0.0	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
HLKPNGBE_01094	1.52e-120	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HLKPNGBE_01096	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HLKPNGBE_01097	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01098	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HLKPNGBE_01099	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HLKPNGBE_01100	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
HLKPNGBE_01101	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_01102	7.72e-114	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
HLKPNGBE_01103	1.33e-226	ykuO	-	-	-	-	-	-	-
HLKPNGBE_01104	1.3e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLKPNGBE_01105	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLKPNGBE_01106	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLKPNGBE_01107	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HLKPNGBE_01108	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HLKPNGBE_01109	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
HLKPNGBE_01110	6.25e-106	ykuV	-	-	CO	-	-	-	thiol-disulfide
HLKPNGBE_01111	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
HLKPNGBE_01112	1.47e-201	yknT	-	-	-	ko:K06437	-	ko00000	-
HLKPNGBE_01113	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLKPNGBE_01114	6.5e-246	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLKPNGBE_01115	1.05e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HLKPNGBE_01116	3.44e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HLKPNGBE_01117	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HLKPNGBE_01118	6.92e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HLKPNGBE_01119	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLKPNGBE_01120	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLKPNGBE_01121	1.6e-151	yknW	-	-	S	-	-	-	Yip1 domain
HLKPNGBE_01122	4.93e-235	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLKPNGBE_01123	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_01124	2.1e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HLKPNGBE_01125	1.49e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_01126	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HLKPNGBE_01127	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HLKPNGBE_01128	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLKPNGBE_01129	5.43e-52	ykoA	-	-	-	-	-	-	-
HLKPNGBE_01130	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLKPNGBE_01131	2.99e-217	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLKPNGBE_01132	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HLKPNGBE_01133	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HLKPNGBE_01134	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HLKPNGBE_01135	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HLKPNGBE_01136	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HLKPNGBE_01137	9.21e-208	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HLKPNGBE_01138	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HLKPNGBE_01139	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLKPNGBE_01140	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLKPNGBE_01141	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HLKPNGBE_01142	2.03e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HLKPNGBE_01143	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLKPNGBE_01144	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HLKPNGBE_01145	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HLKPNGBE_01146	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLKPNGBE_01147	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLKPNGBE_01148	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLKPNGBE_01149	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLKPNGBE_01150	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HLKPNGBE_01151	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HLKPNGBE_01152	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HLKPNGBE_01153	1.3e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HLKPNGBE_01154	4.48e-35	ykzI	-	-	-	-	-	-	-
HLKPNGBE_01155	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HLKPNGBE_01156	1.48e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HLKPNGBE_01157	1.28e-223	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HLKPNGBE_01158	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HLKPNGBE_01159	0.0	ylaA	-	-	-	-	-	-	-
HLKPNGBE_01160	1.44e-56	ylaB	-	-	-	-	-	-	-
HLKPNGBE_01161	4.51e-118	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_01163	1.74e-57	ylaE	-	-	-	-	-	-	-
HLKPNGBE_01164	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HLKPNGBE_01165	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HLKPNGBE_01166	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
HLKPNGBE_01167	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01168	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLKPNGBE_01169	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HLKPNGBE_01170	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HLKPNGBE_01171	4.25e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLKPNGBE_01172	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HLKPNGBE_01173	2.57e-273	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLKPNGBE_01174	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLKPNGBE_01175	2.97e-214	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HLKPNGBE_01176	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLKPNGBE_01177	5.85e-253	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HLKPNGBE_01178	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLKPNGBE_01179	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HLKPNGBE_01180	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HLKPNGBE_01181	1.04e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HLKPNGBE_01182	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
HLKPNGBE_01183	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HLKPNGBE_01184	4.58e-258	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HLKPNGBE_01185	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
HLKPNGBE_01186	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HLKPNGBE_01187	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HLKPNGBE_01188	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
HLKPNGBE_01189	2.12e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HLKPNGBE_01190	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLKPNGBE_01191	2.73e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HLKPNGBE_01192	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HLKPNGBE_01193	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLKPNGBE_01194	5.94e-301	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HLKPNGBE_01196	1.7e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HLKPNGBE_01197	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLKPNGBE_01198	5.75e-108	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HLKPNGBE_01199	3.26e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
HLKPNGBE_01200	1.66e-216	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLKPNGBE_01201	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HLKPNGBE_01202	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLKPNGBE_01203	4.97e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLKPNGBE_01204	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HLKPNGBE_01205	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLKPNGBE_01206	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HLKPNGBE_01207	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLKPNGBE_01208	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLKPNGBE_01209	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLKPNGBE_01210	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLKPNGBE_01211	9.42e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLKPNGBE_01212	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HLKPNGBE_01213	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLKPNGBE_01214	3.45e-146	ylxW	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01215	1.06e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01216	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
HLKPNGBE_01217	8.45e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLKPNGBE_01218	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLKPNGBE_01219	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HLKPNGBE_01220	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HLKPNGBE_01221	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_01222	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_01223	3.84e-189	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HLKPNGBE_01224	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HLKPNGBE_01225	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
HLKPNGBE_01226	5.53e-205	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HLKPNGBE_01227	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLKPNGBE_01228	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLKPNGBE_01229	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HLKPNGBE_01230	3.67e-179	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HLKPNGBE_01231	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HLKPNGBE_01232	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLKPNGBE_01233	1.58e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HLKPNGBE_01234	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLKPNGBE_01235	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLKPNGBE_01236	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLKPNGBE_01237	2.24e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HLKPNGBE_01238	4.4e-215	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLKPNGBE_01239	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLKPNGBE_01240	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLKPNGBE_01241	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HLKPNGBE_01242	3.84e-185	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HLKPNGBE_01243	1.33e-224	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLKPNGBE_01244	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLKPNGBE_01245	3.8e-150	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLKPNGBE_01247	3.58e-183	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HLKPNGBE_01248	7.32e-230	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HLKPNGBE_01249	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HLKPNGBE_01250	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HLKPNGBE_01251	1.24e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HLKPNGBE_01252	4.33e-189	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HLKPNGBE_01253	2.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HLKPNGBE_01254	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HLKPNGBE_01255	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HLKPNGBE_01256	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
HLKPNGBE_01257	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HLKPNGBE_01258	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLKPNGBE_01259	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLKPNGBE_01260	4.59e-289	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLKPNGBE_01261	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLKPNGBE_01262	2.89e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLKPNGBE_01263	2.21e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLKPNGBE_01264	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLKPNGBE_01265	3.73e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLKPNGBE_01266	3.03e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HLKPNGBE_01267	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLKPNGBE_01268	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLKPNGBE_01269	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HLKPNGBE_01270	2.83e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HLKPNGBE_01271	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HLKPNGBE_01272	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01273	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HLKPNGBE_01274	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HLKPNGBE_01275	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HLKPNGBE_01276	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLKPNGBE_01277	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HLKPNGBE_01278	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLKPNGBE_01279	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HLKPNGBE_01280	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HLKPNGBE_01281	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLKPNGBE_01282	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLKPNGBE_01283	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HLKPNGBE_01284	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLKPNGBE_01285	1.67e-114	-	-	-	-	-	-	-	-
HLKPNGBE_01286	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLKPNGBE_01287	9.7e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLKPNGBE_01288	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLKPNGBE_01289	2.95e-50	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HLKPNGBE_01290	5.89e-81	ylqD	-	-	S	-	-	-	YlqD protein
HLKPNGBE_01291	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLKPNGBE_01292	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLKPNGBE_01293	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLKPNGBE_01294	1.2e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLKPNGBE_01295	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLKPNGBE_01296	0.0	ylqG	-	-	-	-	-	-	-
HLKPNGBE_01297	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HLKPNGBE_01298	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HLKPNGBE_01299	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HLKPNGBE_01300	6.53e-218	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HLKPNGBE_01301	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLKPNGBE_01302	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLKPNGBE_01303	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HLKPNGBE_01304	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLKPNGBE_01305	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLKPNGBE_01306	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HLKPNGBE_01307	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HLKPNGBE_01308	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HLKPNGBE_01309	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HLKPNGBE_01310	7.38e-35	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HLKPNGBE_01311	1.66e-292	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HLKPNGBE_01312	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLKPNGBE_01313	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HLKPNGBE_01314	2.11e-308	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HLKPNGBE_01315	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HLKPNGBE_01316	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HLKPNGBE_01317	2.31e-314	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HLKPNGBE_01318	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HLKPNGBE_01319	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HLKPNGBE_01320	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HLKPNGBE_01321	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLKPNGBE_01322	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HLKPNGBE_01323	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HLKPNGBE_01324	5.54e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HLKPNGBE_01325	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HLKPNGBE_01326	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HLKPNGBE_01327	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HLKPNGBE_01328	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLKPNGBE_01329	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLKPNGBE_01330	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HLKPNGBE_01331	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HLKPNGBE_01332	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HLKPNGBE_01333	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HLKPNGBE_01334	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HLKPNGBE_01335	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HLKPNGBE_01336	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HLKPNGBE_01337	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_01338	6.91e-101	ylxL	-	-	-	-	-	-	-
HLKPNGBE_01339	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLKPNGBE_01340	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLKPNGBE_01341	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLKPNGBE_01342	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLKPNGBE_01343	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLKPNGBE_01344	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HLKPNGBE_01345	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HLKPNGBE_01346	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HLKPNGBE_01347	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLKPNGBE_01348	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLKPNGBE_01349	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HLKPNGBE_01350	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLKPNGBE_01351	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HLKPNGBE_01352	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HLKPNGBE_01353	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLKPNGBE_01354	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HLKPNGBE_01355	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLKPNGBE_01356	5.18e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLKPNGBE_01357	1.63e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLKPNGBE_01358	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLKPNGBE_01359	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLKPNGBE_01360	1.29e-235	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HLKPNGBE_01361	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HLKPNGBE_01362	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HLKPNGBE_01363	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HLKPNGBE_01364	9.94e-142	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HLKPNGBE_01365	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLKPNGBE_01366	1.2e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLKPNGBE_01367	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLKPNGBE_01368	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLKPNGBE_01369	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HLKPNGBE_01370	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
HLKPNGBE_01371	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLKPNGBE_01372	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_01373	2.08e-267	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_01374	2.96e-302	albE	-	-	S	-	-	-	Peptidase M16
HLKPNGBE_01375	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
HLKPNGBE_01376	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HLKPNGBE_01377	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HLKPNGBE_01378	4.57e-182	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HLKPNGBE_01379	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HLKPNGBE_01380	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLKPNGBE_01381	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HLKPNGBE_01382	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLKPNGBE_01383	8.43e-282	pbpX	-	-	V	-	-	-	Beta-lactamase
HLKPNGBE_01384	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HLKPNGBE_01385	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HLKPNGBE_01386	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HLKPNGBE_01387	3.02e-255	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HLKPNGBE_01388	1.02e-278	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLKPNGBE_01389	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLKPNGBE_01390	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HLKPNGBE_01391	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HLKPNGBE_01392	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLKPNGBE_01393	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLKPNGBE_01394	7.19e-93	-	-	-	S	-	-	-	Regulatory protein YrvL
HLKPNGBE_01396	1.38e-127	ymcC	-	-	S	-	-	-	Membrane
HLKPNGBE_01397	2.94e-141	pksA	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_01398	4.02e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HLKPNGBE_01399	1.31e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HLKPNGBE_01400	2.08e-239	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HLKPNGBE_01401	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HLKPNGBE_01402	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HLKPNGBE_01403	5.31e-304	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLKPNGBE_01404	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HLKPNGBE_01405	2.48e-184	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HLKPNGBE_01406	2.69e-177	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HLKPNGBE_01407	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HLKPNGBE_01408	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HLKPNGBE_01409	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HLKPNGBE_01410	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HLKPNGBE_01411	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HLKPNGBE_01412	2.49e-297	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLKPNGBE_01413	2.8e-81	ymzB	-	-	-	-	-	-	-
HLKPNGBE_01414	4.8e-210	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLKPNGBE_01415	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HLKPNGBE_01416	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
HLKPNGBE_01417	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HLKPNGBE_01418	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
HLKPNGBE_01419	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HLKPNGBE_01421	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
HLKPNGBE_01422	9.69e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLKPNGBE_01423	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HLKPNGBE_01424	8.07e-32	-	-	-	-	-	-	-	-
HLKPNGBE_01425	1.2e-30	ymzA	-	-	-	-	-	-	-
HLKPNGBE_01426	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HLKPNGBE_01427	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLKPNGBE_01428	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLKPNGBE_01429	2.24e-141	-	-	-	-	-	-	-	-
HLKPNGBE_01430	1.72e-151	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HLKPNGBE_01431	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HLKPNGBE_01432	4.47e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLKPNGBE_01433	5.82e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HLKPNGBE_01434	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HLKPNGBE_01435	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLKPNGBE_01436	2.95e-14	-	-	-	-	-	-	-	-
HLKPNGBE_01437	2.61e-40	-	-	-	-	-	-	-	-
HLKPNGBE_01438	7.13e-52	-	-	-	-	-	-	-	-
HLKPNGBE_01439	5.4e-105	-	-	-	G	-	-	-	regulation of fungal-type cell wall biogenesis
HLKPNGBE_01440	1.97e-186	ynaC	-	-	-	-	-	-	-
HLKPNGBE_01441	7.56e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_01442	1.65e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HLKPNGBE_01443	1.06e-80	ynaF	-	-	-	-	-	-	-
HLKPNGBE_01446	4.32e-110	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
HLKPNGBE_01447	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HLKPNGBE_01448	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLKPNGBE_01449	3.15e-278	xylR	-	-	GK	-	-	-	ROK family
HLKPNGBE_01450	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HLKPNGBE_01451	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HLKPNGBE_01452	9.1e-148	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HLKPNGBE_01453	3.64e-313	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLKPNGBE_01454	3.05e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLKPNGBE_01455	3.44e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HLKPNGBE_01456	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HLKPNGBE_01457	7.54e-22	-	-	-	-	-	-	-	-
HLKPNGBE_01460	7.03e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLKPNGBE_01462	1.55e-172	-	-	-	S	-	-	-	Domain of unknown function, YrpD
HLKPNGBE_01465	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
HLKPNGBE_01466	8.92e-96	-	-	-	-	-	-	-	-
HLKPNGBE_01467	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HLKPNGBE_01470	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HLKPNGBE_01471	2.38e-251	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
HLKPNGBE_01472	9.64e-290	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HLKPNGBE_01473	9.15e-199	yndG	-	-	S	-	-	-	DoxX-like family
HLKPNGBE_01474	1.26e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HLKPNGBE_01475	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HLKPNGBE_01477	1.68e-177	yndL	-	-	S	-	-	-	Replication protein
HLKPNGBE_01478	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HLKPNGBE_01479	4.44e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HLKPNGBE_01481	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLKPNGBE_01482	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HLKPNGBE_01483	3.97e-145	yneB	-	-	L	-	-	-	resolvase
HLKPNGBE_01484	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HLKPNGBE_01485	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLKPNGBE_01486	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HLKPNGBE_01487	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HLKPNGBE_01488	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HLKPNGBE_01489	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HLKPNGBE_01490	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HLKPNGBE_01491	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HLKPNGBE_01492	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HLKPNGBE_01493	1.21e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HLKPNGBE_01494	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HLKPNGBE_01495	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HLKPNGBE_01496	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HLKPNGBE_01497	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLKPNGBE_01498	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
HLKPNGBE_01500	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HLKPNGBE_01501	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HLKPNGBE_01502	1.63e-71	yneQ	-	-	-	-	-	-	-
HLKPNGBE_01503	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HLKPNGBE_01504	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLKPNGBE_01505	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HLKPNGBE_01506	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLKPNGBE_01507	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLKPNGBE_01508	1.82e-18	-	-	-	-	-	-	-	-
HLKPNGBE_01509	1.06e-75	ynfC	-	-	-	-	-	-	-
HLKPNGBE_01510	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HLKPNGBE_01511	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HLKPNGBE_01513	0.0	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HLKPNGBE_01514	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLKPNGBE_01515	1.04e-104	yngA	-	-	S	-	-	-	membrane
HLKPNGBE_01516	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLKPNGBE_01517	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
HLKPNGBE_01518	4.46e-297	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
HLKPNGBE_01519	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLKPNGBE_01520	1.48e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HLKPNGBE_01521	7.02e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HLKPNGBE_01522	1.23e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HLKPNGBE_01523	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HLKPNGBE_01524	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLKPNGBE_01525	1.31e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HLKPNGBE_01526	4.3e-41	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
HLKPNGBE_01527	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HLKPNGBE_01528	2.12e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HLKPNGBE_01529	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
HLKPNGBE_01530	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_01531	1.16e-104	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HLKPNGBE_01532	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01533	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLKPNGBE_01534	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLKPNGBE_01535	2.5e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLKPNGBE_01536	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLKPNGBE_01537	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLKPNGBE_01538	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLKPNGBE_01539	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HLKPNGBE_01540	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLKPNGBE_01541	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLKPNGBE_01542	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HLKPNGBE_01543	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HLKPNGBE_01545	1.77e-276	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HLKPNGBE_01546	2.26e-37	-	-	-	-	-	-	-	-
HLKPNGBE_01547	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HLKPNGBE_01548	3.68e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HLKPNGBE_01549	5.7e-281	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLKPNGBE_01550	7.2e-201	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HLKPNGBE_01551	5.16e-270	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HLKPNGBE_01552	1.66e-267	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HLKPNGBE_01553	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HLKPNGBE_01554	1.07e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HLKPNGBE_01555	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HLKPNGBE_01556	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HLKPNGBE_01557	6.35e-201	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HLKPNGBE_01558	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLKPNGBE_01559	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HLKPNGBE_01560	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLKPNGBE_01561	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLKPNGBE_01562	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLKPNGBE_01563	1.57e-296	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLKPNGBE_01564	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
HLKPNGBE_01565	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_01566	4.23e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLKPNGBE_01567	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HLKPNGBE_01568	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLKPNGBE_01569	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLKPNGBE_01570	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLKPNGBE_01571	9.33e-226	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HLKPNGBE_01572	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01574	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HLKPNGBE_01575	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLKPNGBE_01576	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HLKPNGBE_01577	8.77e-184	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
HLKPNGBE_01578	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLKPNGBE_01579	1.77e-32	yqzJ	-	-	-	-	-	-	-
HLKPNGBE_01580	2.72e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLKPNGBE_01581	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLKPNGBE_01582	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLKPNGBE_01583	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLKPNGBE_01584	3.86e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLKPNGBE_01585	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HLKPNGBE_01586	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HLKPNGBE_01587	6.84e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLKPNGBE_01588	3.98e-230	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLKPNGBE_01589	3.41e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_01590	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HLKPNGBE_01591	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HLKPNGBE_01592	1.33e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLKPNGBE_01594	1.08e-289	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
HLKPNGBE_01596	4.03e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLKPNGBE_01597	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
HLKPNGBE_01598	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HLKPNGBE_01599	5.51e-79	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HLKPNGBE_01600	2.89e-251	yqkA	-	-	K	-	-	-	GrpB protein
HLKPNGBE_01601	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HLKPNGBE_01602	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HLKPNGBE_01603	4.29e-227	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HLKPNGBE_01604	1.78e-29	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HLKPNGBE_01605	9.26e-218	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HLKPNGBE_01606	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HLKPNGBE_01607	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HLKPNGBE_01608	2.62e-283	yqxK	-	-	L	-	-	-	DNA helicase
HLKPNGBE_01609	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_01610	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HLKPNGBE_01611	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HLKPNGBE_01612	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HLKPNGBE_01613	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HLKPNGBE_01614	3.73e-44	yqkK	-	-	-	-	-	-	-
HLKPNGBE_01615	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HLKPNGBE_01616	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HLKPNGBE_01617	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HLKPNGBE_01618	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HLKPNGBE_01619	2.89e-295	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLKPNGBE_01620	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HLKPNGBE_01621	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLKPNGBE_01622	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HLKPNGBE_01623	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HLKPNGBE_01624	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_01625	5.72e-144	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HLKPNGBE_01626	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HLKPNGBE_01627	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HLKPNGBE_01628	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HLKPNGBE_01629	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HLKPNGBE_01630	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HLKPNGBE_01631	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HLKPNGBE_01632	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLKPNGBE_01633	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
HLKPNGBE_01634	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLKPNGBE_01636	3.82e-09	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLKPNGBE_01638	1.28e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
HLKPNGBE_01639	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLKPNGBE_01640	2.96e-72	ypuD	-	-	-	-	-	-	-
HLKPNGBE_01641	1.77e-261	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLKPNGBE_01642	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HLKPNGBE_01643	3.12e-292	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLKPNGBE_01644	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLKPNGBE_01645	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_01646	3.34e-93	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HLKPNGBE_01647	1.33e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLKPNGBE_01648	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLKPNGBE_01649	6.13e-128	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HLKPNGBE_01650	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLKPNGBE_01651	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HLKPNGBE_01652	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HLKPNGBE_01653	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLKPNGBE_01654	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HLKPNGBE_01655	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HLKPNGBE_01656	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HLKPNGBE_01657	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_01658	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_01659	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_01660	2.7e-257	rsiX	-	-	-	-	-	-	-
HLKPNGBE_01661	2.89e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLKPNGBE_01662	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLKPNGBE_01663	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLKPNGBE_01664	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HLKPNGBE_01665	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HLKPNGBE_01666	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLKPNGBE_01667	6.13e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HLKPNGBE_01668	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
HLKPNGBE_01669	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HLKPNGBE_01670	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HLKPNGBE_01671	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLKPNGBE_01672	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLKPNGBE_01673	1.62e-227	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HLKPNGBE_01674	4.33e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HLKPNGBE_01675	4.88e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HLKPNGBE_01676	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HLKPNGBE_01677	4.63e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HLKPNGBE_01678	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HLKPNGBE_01679	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HLKPNGBE_01680	9.5e-263	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLKPNGBE_01681	8.41e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLKPNGBE_01682	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
HLKPNGBE_01683	2.73e-134	yphA	-	-	-	-	-	-	-
HLKPNGBE_01684	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
HLKPNGBE_01685	8.69e-40	ypzH	-	-	-	-	-	-	-
HLKPNGBE_01686	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLKPNGBE_01687	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HLKPNGBE_01688	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HLKPNGBE_01689	9.07e-178	yphF	-	-	-	-	-	-	-
HLKPNGBE_01690	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HLKPNGBE_01691	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLKPNGBE_01692	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HLKPNGBE_01693	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HLKPNGBE_01694	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HLKPNGBE_01695	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLKPNGBE_01696	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLKPNGBE_01697	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HLKPNGBE_01698	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HLKPNGBE_01699	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLKPNGBE_01700	8.48e-265	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLKPNGBE_01701	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HLKPNGBE_01702	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLKPNGBE_01703	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLKPNGBE_01704	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HLKPNGBE_01705	2.82e-153	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HLKPNGBE_01706	9.33e-295	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLKPNGBE_01707	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLKPNGBE_01708	4.5e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLKPNGBE_01709	1.71e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HLKPNGBE_01710	9.91e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLKPNGBE_01711	5.27e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLKPNGBE_01712	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HLKPNGBE_01713	4.75e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HLKPNGBE_01714	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HLKPNGBE_01715	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HLKPNGBE_01716	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HLKPNGBE_01717	1.63e-125	ypjA	-	-	S	-	-	-	membrane
HLKPNGBE_01718	6.84e-183	ypjB	-	-	S	-	-	-	sporulation protein
HLKPNGBE_01719	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLKPNGBE_01720	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HLKPNGBE_01721	8.38e-190	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLKPNGBE_01722	1.52e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HLKPNGBE_01723	6.61e-167	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HLKPNGBE_01724	1.04e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HLKPNGBE_01725	1.41e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLKPNGBE_01726	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLKPNGBE_01727	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HLKPNGBE_01728	1.34e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HLKPNGBE_01729	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HLKPNGBE_01730	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HLKPNGBE_01731	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HLKPNGBE_01732	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01733	1.07e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HLKPNGBE_01734	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HLKPNGBE_01735	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HLKPNGBE_01736	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLKPNGBE_01737	1.43e-121	ypoC	-	-	-	-	-	-	-
HLKPNGBE_01738	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLKPNGBE_01739	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLKPNGBE_01740	4.54e-241	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HLKPNGBE_01743	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HLKPNGBE_01744	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
HLKPNGBE_01745	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
HLKPNGBE_01746	4.33e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLKPNGBE_01747	2.34e-113	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HLKPNGBE_01748	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HLKPNGBE_01749	7.21e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HLKPNGBE_01750	3.41e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HLKPNGBE_01751	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLKPNGBE_01752	2.84e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HLKPNGBE_01754	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HLKPNGBE_01755	2.05e-179	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_01756	1.25e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HLKPNGBE_01757	1.92e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HLKPNGBE_01758	6.95e-238	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HLKPNGBE_01759	2.53e-133	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HLKPNGBE_01760	1e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HLKPNGBE_01761	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HLKPNGBE_01762	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLKPNGBE_01763	3.14e-294	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HLKPNGBE_01764	4.55e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HLKPNGBE_01765	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HLKPNGBE_01766	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HLKPNGBE_01767	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HLKPNGBE_01768	1.08e-11	-	-	-	-	-	-	-	-
HLKPNGBE_01769	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
HLKPNGBE_01770	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
HLKPNGBE_01771	1.6e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HLKPNGBE_01772	2.4e-138	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HLKPNGBE_01773	4e-163	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HLKPNGBE_01774	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
HLKPNGBE_01775	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HLKPNGBE_01776	1.17e-22	degR	-	-	-	-	-	-	-
HLKPNGBE_01777	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HLKPNGBE_01778	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HLKPNGBE_01779	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLKPNGBE_01780	1.89e-115	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HLKPNGBE_01781	2.52e-142	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HLKPNGBE_01782	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HLKPNGBE_01783	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HLKPNGBE_01784	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HLKPNGBE_01785	6.15e-187	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HLKPNGBE_01786	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
HLKPNGBE_01787	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HLKPNGBE_01788	7.27e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLKPNGBE_01789	1.21e-124	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLKPNGBE_01790	1.71e-145	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLKPNGBE_01791	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HLKPNGBE_01792	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_01793	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HLKPNGBE_01794	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HLKPNGBE_01795	2.77e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HLKPNGBE_01796	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLKPNGBE_01797	6.8e-129	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01798	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
HLKPNGBE_01799	3.49e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
HLKPNGBE_01800	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
HLKPNGBE_01801	8.41e-134	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLKPNGBE_01802	3.52e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HLKPNGBE_01803	1.76e-124	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HLKPNGBE_01804	0.0	yokA	-	-	L	-	-	-	Recombinase
HLKPNGBE_01805	4.93e-153	-	-	-	-	-	-	-	-
HLKPNGBE_01806	5.1e-123	-	-	-	-	-	-	-	-
HLKPNGBE_01809	8.79e-199	yokD	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	aminoglycoside
HLKPNGBE_01810	6.83e-109	-	-	-	S	-	-	-	Bacterial PH domain
HLKPNGBE_01811	2.55e-178	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HLKPNGBE_01812	5.27e-261	-	-	-	-	-	-	-	-
HLKPNGBE_01813	2.64e-119	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HLKPNGBE_01814	0.0	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HLKPNGBE_01815	9.26e-123	-	-	-	S	ko:K21490	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
HLKPNGBE_01816	5.38e-142	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HLKPNGBE_01817	5.26e-128	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLKPNGBE_01821	7.43e-49	-	-	-	-	-	-	-	-
HLKPNGBE_01822	7.69e-73	-	-	-	S	-	-	-	YolD-like protein
HLKPNGBE_01823	2.97e-306	-	-	-	S	-	-	-	damaged DNA binding
HLKPNGBE_01826	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	Peptidase C39 family
HLKPNGBE_01827	3.44e-91	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
HLKPNGBE_01828	6.04e-309	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLKPNGBE_01829	5.12e-96	-	-	-	O	ko:K03611	-	ko00000,ko03110	protein disulfide oxidoreductase activity
HLKPNGBE_01830	3.04e-53	-	-	-	S	-	-	-	SPP1 phage holin
HLKPNGBE_01831	1.42e-43	bhlA	-	-	S	-	-	-	BhlA holin family
HLKPNGBE_01832	7.44e-257	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
HLKPNGBE_01834	1.31e-210	-	-	-	-	-	-	-	-
HLKPNGBE_01835	0.0	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
HLKPNGBE_01836	9.28e-166	-	-	-	-	-	-	-	-
HLKPNGBE_01837	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
HLKPNGBE_01838	1.7e-186	-	-	-	S	-	-	-	Phage tail protein
HLKPNGBE_01839	0.0	-	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLKPNGBE_01840	5.66e-159	-	-	-	-	-	-	-	-
HLKPNGBE_01845	1.73e-247	-	-	-	A	-	-	-	Belongs to the 'phage' integrase family
HLKPNGBE_01846	2e-94	-	-	-	-	-	-	-	-
HLKPNGBE_01847	1.65e-112	-	-	-	-	-	-	-	-
HLKPNGBE_01850	4.46e-229	-	-	-	-	-	-	-	-
HLKPNGBE_01851	2.22e-76	-	-	-	-	-	-	-	-
HLKPNGBE_01854	1.58e-145	-	-	-	-	-	-	-	-
HLKPNGBE_01855	2.4e-169	-	-	-	-	-	-	-	-
HLKPNGBE_01856	4.38e-118	-	-	-	-	-	-	-	-
HLKPNGBE_01857	9.48e-157	-	-	-	-	-	-	-	-
HLKPNGBE_01859	8.95e-91	-	-	-	-	-	-	-	-
HLKPNGBE_01860	8.05e-106	-	-	-	-	-	-	-	-
HLKPNGBE_01861	5.93e-237	-	-	-	-	-	-	-	-
HLKPNGBE_01862	1.24e-122	-	-	-	-	-	-	-	-
HLKPNGBE_01863	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_01864	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_01865	0.0	-	-	-	S	-	-	-	Terminase-like family
HLKPNGBE_01866	4.45e-225	-	-	-	-	-	-	-	-
HLKPNGBE_01869	2.29e-293	-	-	-	-	-	-	-	-
HLKPNGBE_01871	7.27e-56	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLKPNGBE_01872	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_01875	6.64e-73	bldD	-	-	K	ko:K07110,ko:K21572	-	ko00000,ko02000,ko03000	domain, Protein
HLKPNGBE_01878	1.07e-305	-	-	-	-	-	-	-	-
HLKPNGBE_01880	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_01881	7.56e-48	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLKPNGBE_01882	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_01888	2.68e-124	-	-	-	S	-	-	-	Super-infection exclusion protein B
HLKPNGBE_01889	8.39e-125	-	-	-	-	-	-	-	-
HLKPNGBE_01891	7.95e-135	-	-	-	-	-	-	-	-
HLKPNGBE_01896	2.04e-254	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLKPNGBE_01897	0.0	-	-	-	S	-	-	-	DNA-sulfur modification-associated
HLKPNGBE_01898	2.89e-226	-	-	-	-	-	-	-	-
HLKPNGBE_01899	4.78e-46	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_01904	0.000573	-	-	-	S	-	-	-	YopX protein
HLKPNGBE_01910	2.12e-175	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HLKPNGBE_01911	2.65e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HLKPNGBE_01914	1.16e-102	yoqH	-	-	M	-	-	-	LysM domain
HLKPNGBE_01916	9.17e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1273)
HLKPNGBE_01918	3.88e-60	-	-	-	-	-	-	-	-
HLKPNGBE_01925	6.17e-103	-	-	-	-	-	-	-	-
HLKPNGBE_01926	3.73e-199	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
HLKPNGBE_01927	2.62e-167	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HLKPNGBE_01930	1.83e-192	-	-	-	S	-	-	-	Pfam:DUF867
HLKPNGBE_01931	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HLKPNGBE_01936	2.37e-219	-	-	-	-	-	-	-	-
HLKPNGBE_01937	6.35e-229	-	-	-	L	-	-	-	AAA domain
HLKPNGBE_01938	1.1e-112	-	-	-	-	-	-	-	-
HLKPNGBE_01939	0.0	-	-	-	J	-	-	-	DnaB-like helicase C terminal domain
HLKPNGBE_01940	3.45e-288	-	-	-	L	-	-	-	DNA primase activity
HLKPNGBE_01941	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLKPNGBE_01942	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLKPNGBE_01943	9.54e-147	-	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_01948	3.92e-115	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
HLKPNGBE_01949	1.71e-126	yorS	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HLKPNGBE_01951	0.0	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HLKPNGBE_01968	7.75e-87	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HLKPNGBE_01969	1.71e-160	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLKPNGBE_01970	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLKPNGBE_01971	1.59e-139	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLKPNGBE_01972	3.73e-126	-	-	-	L	-	-	-	HNH endonuclease
HLKPNGBE_01973	1.12e-87	-	-	-	S	-	-	-	Ribonucleotide reductase, small chain
HLKPNGBE_01974	2.34e-51	-	-	-	O	-	-	-	Glutaredoxin
HLKPNGBE_01975	3.02e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HLKPNGBE_01976	2.85e-107	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HLKPNGBE_01981	2.24e-41	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HLKPNGBE_01982	6.52e-216	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLKPNGBE_01991	1.31e-139	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLKPNGBE_01993	1.13e-82	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HLKPNGBE_01994	4.17e-282	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HLKPNGBE_01995	2.95e-240	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HLKPNGBE_01996	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
HLKPNGBE_01997	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
HLKPNGBE_01998	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HLKPNGBE_01999	2.06e-186	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HLKPNGBE_02002	0.0	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLKPNGBE_02004	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLKPNGBE_02005	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HLKPNGBE_02006	9.5e-200	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HLKPNGBE_02007	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HLKPNGBE_02008	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HLKPNGBE_02009	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HLKPNGBE_02010	3.84e-161	yodN	-	-	-	-	-	-	-
HLKPNGBE_02012	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
HLKPNGBE_02013	4.02e-138	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HLKPNGBE_02014	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
HLKPNGBE_02015	2.08e-12	-	-	-	-	-	-	-	-
HLKPNGBE_02016	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HLKPNGBE_02017	1.62e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HLKPNGBE_02018	2.93e-42	yodI	-	-	-	-	-	-	-
HLKPNGBE_02019	6.38e-168	yodH	-	-	Q	-	-	-	Methyltransferase
HLKPNGBE_02020	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HLKPNGBE_02021	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLKPNGBE_02022	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HLKPNGBE_02023	1.18e-223	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HLKPNGBE_02024	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HLKPNGBE_02025	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
HLKPNGBE_02026	1.37e-76	yodB	-	-	K	-	-	-	transcriptional
HLKPNGBE_02027	2.05e-86	iolK	-	-	S	-	-	-	tautomerase
HLKPNGBE_02028	1.01e-293	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HLKPNGBE_02029	1.95e-14	-	-	-	-	-	-	-	-
HLKPNGBE_02030	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HLKPNGBE_02031	1.21e-209	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HLKPNGBE_02032	1.85e-58	-	-	-	-	-	-	-	-
HLKPNGBE_02033	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HLKPNGBE_02034	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HLKPNGBE_02035	2.49e-194	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLKPNGBE_02036	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HLKPNGBE_02038	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLKPNGBE_02039	5.62e-294	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HLKPNGBE_02040	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HLKPNGBE_02041	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HLKPNGBE_02042	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HLKPNGBE_02043	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HLKPNGBE_02044	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HLKPNGBE_02045	3.16e-265	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HLKPNGBE_02046	2.72e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HLKPNGBE_02047	4.35e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLKPNGBE_02048	3.35e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HLKPNGBE_02049	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HLKPNGBE_02050	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLKPNGBE_02051	1.91e-42	yozC	-	-	-	-	-	-	-
HLKPNGBE_02052	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
HLKPNGBE_02053	1.83e-49	yocN	-	-	-	-	-	-	-
HLKPNGBE_02054	2.94e-55	yozN	-	-	-	-	-	-	-
HLKPNGBE_02055	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLKPNGBE_02056	7.29e-46	-	-	-	-	-	-	-	-
HLKPNGBE_02057	3.02e-70	yocL	-	-	-	-	-	-	-
HLKPNGBE_02058	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
HLKPNGBE_02059	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLKPNGBE_02060	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLKPNGBE_02061	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HLKPNGBE_02062	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_02063	1.22e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_02064	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HLKPNGBE_02065	1.21e-243	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HLKPNGBE_02066	1.32e-122	yocC	-	-	-	-	-	-	-
HLKPNGBE_02067	4.49e-186	-	-	-	-	-	-	-	-
HLKPNGBE_02068	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HLKPNGBE_02069	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLKPNGBE_02070	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HLKPNGBE_02071	7.69e-123	yobW	-	-	-	-	-	-	-
HLKPNGBE_02072	2.05e-229	yobV	-	-	K	-	-	-	WYL domain
HLKPNGBE_02073	1.55e-114	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HLKPNGBE_02074	1.34e-169	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLKPNGBE_02075	9.22e-129	yobS	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02076	1.29e-183	-	-	-	J	-	-	-	FR47-like protein
HLKPNGBE_02077	5.23e-175	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLKPNGBE_02078	2.21e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HLKPNGBE_02079	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HLKPNGBE_02080	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
HLKPNGBE_02081	4.3e-136	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HLKPNGBE_02082	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HLKPNGBE_02083	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HLKPNGBE_02084	3.58e-202	-	-	-	-	-	-	-	-
HLKPNGBE_02085	0.0	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLKPNGBE_02086	2.08e-64	-	-	-	-	-	-	-	-
HLKPNGBE_02087	2.05e-51	-	-	-	S	-	-	-	YolD-like protein
HLKPNGBE_02088	1.52e-79	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLKPNGBE_02089	6.17e-158	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLKPNGBE_02091	6.23e-267	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HLKPNGBE_02095	1.36e-08	-	-	-	-	-	-	-	-
HLKPNGBE_02096	6.85e-229	-	-	-	-	-	-	-	-
HLKPNGBE_02097	1.92e-162	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HLKPNGBE_02098	1.21e-90	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HLKPNGBE_02100	3.92e-76	-	-	-	K	-	-	-	Helix-turn-helix
HLKPNGBE_02101	6.27e-51	-	-	-	S	-	-	-	TM2 domain
HLKPNGBE_02102	1.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HLKPNGBE_02103	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HLKPNGBE_02107	9.26e-218	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HLKPNGBE_02108	3.88e-153	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HLKPNGBE_02109	6.84e-103	yoaW	-	-	-	-	-	-	-
HLKPNGBE_02110	1.11e-202	yoaV	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_02111	6.67e-203	yoaU	-	-	K	-	-	-	LysR substrate binding domain
HLKPNGBE_02112	6.92e-192	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HLKPNGBE_02113	7.38e-50	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02114	1.6e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HLKPNGBE_02115	3.63e-218	yoaR	-	-	V	-	-	-	vancomycin resistance protein
HLKPNGBE_02116	2.36e-116	-	-	-	-	-	-	-	-
HLKPNGBE_02117	7.38e-88	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HLKPNGBE_02118	4.7e-188	yoaP	-	-	K	-	-	-	YoaP-like
HLKPNGBE_02120	1.95e-296	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HLKPNGBE_02122	5.08e-171	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HLKPNGBE_02123	1.5e-254	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
HLKPNGBE_02124	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
HLKPNGBE_02125	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
HLKPNGBE_02126	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HLKPNGBE_02127	0.0	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HLKPNGBE_02128	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HLKPNGBE_02129	1.25e-20	-	-	-	-	-	-	-	-
HLKPNGBE_02131	2.08e-44	yoaF	-	-	-	-	-	-	-
HLKPNGBE_02132	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLKPNGBE_02133	3.41e-243	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLKPNGBE_02134	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HLKPNGBE_02135	1.11e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HLKPNGBE_02136	5.91e-125	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLKPNGBE_02137	1.34e-185	yoxB	-	-	-	-	-	-	-
HLKPNGBE_02138	8.39e-57	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HLKPNGBE_02139	7.94e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_02140	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HLKPNGBE_02141	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLKPNGBE_02142	8.13e-263	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLKPNGBE_02143	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02144	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HLKPNGBE_02145	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HLKPNGBE_02146	7.23e-238	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HLKPNGBE_02147	1.3e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02148	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HLKPNGBE_02149	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HLKPNGBE_02150	1.14e-124	-	-	-	L	-	-	-	Integrase
HLKPNGBE_02152	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HLKPNGBE_02153	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
HLKPNGBE_02154	2.54e-245	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLKPNGBE_02155	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HLKPNGBE_02156	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_02157	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_02168	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLKPNGBE_02169	2.96e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLKPNGBE_02170	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HLKPNGBE_02171	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLKPNGBE_02172	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLKPNGBE_02173	1.97e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HLKPNGBE_02174	9.43e-263	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
HLKPNGBE_02175	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
HLKPNGBE_02176	1.7e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
HLKPNGBE_02178	3.7e-300	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
HLKPNGBE_02179	7.74e-231	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
HLKPNGBE_02180	2.03e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLKPNGBE_02181	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HLKPNGBE_02182	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HLKPNGBE_02183	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HLKPNGBE_02184	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HLKPNGBE_02185	5.09e-199	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HLKPNGBE_02186	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLKPNGBE_02187	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLKPNGBE_02188	1.22e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HLKPNGBE_02189	1.13e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLKPNGBE_02190	1.83e-180	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLKPNGBE_02191	1.64e-299	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLKPNGBE_02192	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HLKPNGBE_02193	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HLKPNGBE_02194	2.96e-241	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HLKPNGBE_02195	2.81e-316	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HLKPNGBE_02196	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLKPNGBE_02197	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HLKPNGBE_02198	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLKPNGBE_02199	8.26e-96	ytkA	-	-	S	-	-	-	YtkA-like
HLKPNGBE_02201	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HLKPNGBE_02202	1.59e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HLKPNGBE_02203	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HLKPNGBE_02204	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLKPNGBE_02205	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLKPNGBE_02206	2.77e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HLKPNGBE_02207	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HLKPNGBE_02208	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HLKPNGBE_02209	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HLKPNGBE_02210	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLKPNGBE_02211	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLKPNGBE_02212	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_02213	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HLKPNGBE_02214	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HLKPNGBE_02215	1.96e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HLKPNGBE_02216	6.76e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HLKPNGBE_02217	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HLKPNGBE_02218	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HLKPNGBE_02220	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HLKPNGBE_02221	1.03e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_02222	3.35e-222	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HLKPNGBE_02223	1.07e-189	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HLKPNGBE_02224	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_02225	5.92e-298	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HLKPNGBE_02226	1.77e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_02227	1.58e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HLKPNGBE_02228	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_02229	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HLKPNGBE_02230	2.02e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HLKPNGBE_02231	2.98e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HLKPNGBE_02232	6.61e-184	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HLKPNGBE_02233	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HLKPNGBE_02234	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLKPNGBE_02235	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HLKPNGBE_02236	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HLKPNGBE_02237	1.32e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HLKPNGBE_02238	2.86e-215	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLKPNGBE_02239	4.68e-315	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLKPNGBE_02240	1.12e-244	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02241	1.43e-222	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
HLKPNGBE_02242	4.04e-182	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HLKPNGBE_02243	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HLKPNGBE_02244	3.73e-284	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLKPNGBE_02245	5.04e-164	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HLKPNGBE_02246	4.57e-244	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HLKPNGBE_02247	2.64e-287	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLKPNGBE_02248	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
HLKPNGBE_02249	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HLKPNGBE_02250	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HLKPNGBE_02251	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02252	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HLKPNGBE_02253	2.23e-286	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HLKPNGBE_02254	5.81e-95	yteS	-	-	G	-	-	-	transport
HLKPNGBE_02255	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HLKPNGBE_02256	1.97e-152	yteU	-	-	S	-	-	-	Integral membrane protein
HLKPNGBE_02257	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HLKPNGBE_02258	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HLKPNGBE_02259	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HLKPNGBE_02260	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLKPNGBE_02261	9.04e-171	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLKPNGBE_02262	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HLKPNGBE_02263	2.4e-169	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLKPNGBE_02264	8.45e-263	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HLKPNGBE_02265	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLKPNGBE_02266	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HLKPNGBE_02267	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLKPNGBE_02268	7.71e-133	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HLKPNGBE_02269	4.92e-212	ytlQ	-	-	-	-	-	-	-
HLKPNGBE_02270	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLKPNGBE_02271	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HLKPNGBE_02272	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
HLKPNGBE_02273	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
HLKPNGBE_02274	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLKPNGBE_02275	2.16e-193	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLKPNGBE_02276	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HLKPNGBE_02277	4.06e-68	ytzB	-	-	S	-	-	-	small secreted protein
HLKPNGBE_02278	2.24e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HLKPNGBE_02279	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HLKPNGBE_02280	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HLKPNGBE_02281	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HLKPNGBE_02282	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLKPNGBE_02283	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLKPNGBE_02284	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLKPNGBE_02285	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLKPNGBE_02286	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HLKPNGBE_02287	1.9e-72	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HLKPNGBE_02288	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HLKPNGBE_02289	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HLKPNGBE_02290	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HLKPNGBE_02291	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HLKPNGBE_02292	6.51e-293	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HLKPNGBE_02293	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HLKPNGBE_02294	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HLKPNGBE_02295	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLKPNGBE_02296	6.47e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLKPNGBE_02298	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLKPNGBE_02299	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HLKPNGBE_02300	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HLKPNGBE_02301	2.94e-142	yttP	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02302	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HLKPNGBE_02303	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLKPNGBE_02304	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLKPNGBE_02305	1.22e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HLKPNGBE_02306	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLKPNGBE_02307	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HLKPNGBE_02308	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLKPNGBE_02309	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HLKPNGBE_02310	2.92e-190	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLKPNGBE_02311	6.13e-233	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HLKPNGBE_02312	7.05e-113	yteJ	-	-	S	-	-	-	RDD family
HLKPNGBE_02313	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HLKPNGBE_02314	2.24e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HLKPNGBE_02315	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLKPNGBE_02316	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HLKPNGBE_02317	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLKPNGBE_02318	8.14e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HLKPNGBE_02319	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLKPNGBE_02320	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HLKPNGBE_02322	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_02323	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HLKPNGBE_02324	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HLKPNGBE_02325	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLKPNGBE_02326	3.18e-195	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLKPNGBE_02327	4.01e-194	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLKPNGBE_02328	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLKPNGBE_02329	4.08e-156	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLKPNGBE_02330	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLKPNGBE_02331	1.52e-237	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_02332	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HLKPNGBE_02333	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_02334	1.69e-166	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HLKPNGBE_02335	2.09e-306	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HLKPNGBE_02336	2.24e-206	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLKPNGBE_02337	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HLKPNGBE_02338	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
HLKPNGBE_02339	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HLKPNGBE_02340	1.15e-39	-	-	-	-	-	-	-	-
HLKPNGBE_02341	5.12e-112	ytrI	-	-	-	-	-	-	-
HLKPNGBE_02342	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HLKPNGBE_02343	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLKPNGBE_02344	6.01e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HLKPNGBE_02345	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLKPNGBE_02346	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HLKPNGBE_02347	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLKPNGBE_02348	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HLKPNGBE_02349	5.68e-83	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HLKPNGBE_02350	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HLKPNGBE_02351	9.38e-95	ytwI	-	-	S	-	-	-	membrane
HLKPNGBE_02352	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HLKPNGBE_02353	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HLKPNGBE_02354	2.55e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HLKPNGBE_02355	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_02356	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HLKPNGBE_02357	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLKPNGBE_02358	7e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLKPNGBE_02359	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HLKPNGBE_02360	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLKPNGBE_02361	4.54e-205	ytbE	-	-	S	-	-	-	reductase
HLKPNGBE_02362	5.44e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HLKPNGBE_02363	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02364	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLKPNGBE_02365	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HLKPNGBE_02366	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLKPNGBE_02367	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HLKPNGBE_02368	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HLKPNGBE_02369	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HLKPNGBE_02370	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
HLKPNGBE_02371	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLKPNGBE_02372	2.07e-191	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HLKPNGBE_02373	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_02374	2.9e-168	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HLKPNGBE_02375	2.08e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLKPNGBE_02376	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLKPNGBE_02378	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLKPNGBE_02379	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HLKPNGBE_02380	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLKPNGBE_02381	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
HLKPNGBE_02382	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HLKPNGBE_02383	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HLKPNGBE_02384	4.21e-243	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HLKPNGBE_02385	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HLKPNGBE_02386	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HLKPNGBE_02387	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HLKPNGBE_02388	1.05e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HLKPNGBE_02389	1.47e-288	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HLKPNGBE_02390	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HLKPNGBE_02391	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HLKPNGBE_02392	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HLKPNGBE_02393	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HLKPNGBE_02394	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HLKPNGBE_02396	8.17e-52	ysfE	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
HLKPNGBE_02397	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HLKPNGBE_02398	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HLKPNGBE_02399	6.71e-265	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HLKPNGBE_02400	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HLKPNGBE_02401	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLKPNGBE_02402	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLKPNGBE_02403	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLKPNGBE_02404	6.77e-219	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLKPNGBE_02405	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLKPNGBE_02406	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HLKPNGBE_02407	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HLKPNGBE_02408	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLKPNGBE_02409	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HLKPNGBE_02410	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLKPNGBE_02411	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02412	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HLKPNGBE_02413	1.28e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HLKPNGBE_02414	3.02e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HLKPNGBE_02416	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HLKPNGBE_02417	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLKPNGBE_02418	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLKPNGBE_02419	4.83e-276	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLKPNGBE_02420	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HLKPNGBE_02421	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HLKPNGBE_02422	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HLKPNGBE_02423	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HLKPNGBE_02424	1.6e-103	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HLKPNGBE_02425	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02426	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_02427	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLKPNGBE_02428	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HLKPNGBE_02429	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HLKPNGBE_02430	1.06e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLKPNGBE_02431	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HLKPNGBE_02433	1.01e-184	ysnF	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_02434	3.32e-107	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HLKPNGBE_02436	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HLKPNGBE_02437	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HLKPNGBE_02438	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLKPNGBE_02439	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLKPNGBE_02440	1.06e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLKPNGBE_02441	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLKPNGBE_02442	5.35e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLKPNGBE_02443	2.73e-240	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HLKPNGBE_02444	8.87e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLKPNGBE_02445	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLKPNGBE_02446	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HLKPNGBE_02447	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HLKPNGBE_02448	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HLKPNGBE_02449	8.23e-117	ysxD	-	-	-	-	-	-	-
HLKPNGBE_02450	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HLKPNGBE_02451	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HLKPNGBE_02452	2.66e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HLKPNGBE_02453	1.57e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HLKPNGBE_02454	6.39e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HLKPNGBE_02455	8.99e-315	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HLKPNGBE_02456	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HLKPNGBE_02457	2.91e-253	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HLKPNGBE_02458	1.53e-35	-	-	-	-	-	-	-	-
HLKPNGBE_02459	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLKPNGBE_02460	5.8e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLKPNGBE_02461	3.15e-109	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HLKPNGBE_02462	4.67e-215	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HLKPNGBE_02463	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HLKPNGBE_02464	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HLKPNGBE_02465	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HLKPNGBE_02466	1.91e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HLKPNGBE_02467	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HLKPNGBE_02468	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLKPNGBE_02469	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HLKPNGBE_02470	1.83e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HLKPNGBE_02471	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HLKPNGBE_02472	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLKPNGBE_02473	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HLKPNGBE_02474	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HLKPNGBE_02475	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HLKPNGBE_02476	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLKPNGBE_02477	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HLKPNGBE_02478	4.99e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HLKPNGBE_02479	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HLKPNGBE_02480	1.27e-294	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HLKPNGBE_02481	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HLKPNGBE_02482	8.17e-208	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HLKPNGBE_02483	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HLKPNGBE_02484	1.71e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HLKPNGBE_02485	7.28e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLKPNGBE_02486	8.63e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HLKPNGBE_02487	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HLKPNGBE_02488	2.42e-47	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
HLKPNGBE_02490	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
HLKPNGBE_02491	2.77e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HLKPNGBE_02492	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
HLKPNGBE_02493	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HLKPNGBE_02494	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLKPNGBE_02495	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLKPNGBE_02496	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HLKPNGBE_02497	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLKPNGBE_02498	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLKPNGBE_02499	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HLKPNGBE_02500	1.07e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HLKPNGBE_02501	6.34e-147	yrbG	-	-	S	-	-	-	membrane
HLKPNGBE_02502	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLKPNGBE_02503	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HLKPNGBE_02504	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLKPNGBE_02505	6.51e-114	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HLKPNGBE_02506	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HLKPNGBE_02507	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLKPNGBE_02508	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLKPNGBE_02509	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLKPNGBE_02510	1.6e-89	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLKPNGBE_02511	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HLKPNGBE_02513	1.27e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HLKPNGBE_02514	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HLKPNGBE_02515	3.4e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HLKPNGBE_02516	8.5e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HLKPNGBE_02517	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02518	2.67e-272	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HLKPNGBE_02519	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLKPNGBE_02520	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLKPNGBE_02521	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLKPNGBE_02522	1.23e-108	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_02523	8.4e-42	yrzR	-	-	-	-	-	-	-
HLKPNGBE_02524	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HLKPNGBE_02525	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLKPNGBE_02526	2.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLKPNGBE_02527	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLKPNGBE_02528	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLKPNGBE_02529	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
HLKPNGBE_02530	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLKPNGBE_02531	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HLKPNGBE_02532	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLKPNGBE_02533	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HLKPNGBE_02534	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLKPNGBE_02535	1.7e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HLKPNGBE_02536	6.57e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HLKPNGBE_02537	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HLKPNGBE_02538	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HLKPNGBE_02539	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLKPNGBE_02540	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HLKPNGBE_02541	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HLKPNGBE_02542	7.27e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HLKPNGBE_02543	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HLKPNGBE_02544	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLKPNGBE_02545	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HLKPNGBE_02546	4.24e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLKPNGBE_02547	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
HLKPNGBE_02548	4.26e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HLKPNGBE_02549	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HLKPNGBE_02550	1.08e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HLKPNGBE_02551	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HLKPNGBE_02553	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HLKPNGBE_02554	1.1e-126	yrhH	-	-	Q	-	-	-	methyltransferase
HLKPNGBE_02555	1.12e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HLKPNGBE_02556	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HLKPNGBE_02557	2.67e-62	yrhK	-	-	S	-	-	-	YrhK-like protein
HLKPNGBE_02558	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HLKPNGBE_02559	3.67e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HLKPNGBE_02560	9.97e-114	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_02561	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
HLKPNGBE_02562	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
HLKPNGBE_02563	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_02564	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
HLKPNGBE_02565	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLKPNGBE_02566	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HLKPNGBE_02567	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HLKPNGBE_02568	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HLKPNGBE_02569	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HLKPNGBE_02570	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HLKPNGBE_02571	4.3e-256	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HLKPNGBE_02572	3.03e-40	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
HLKPNGBE_02573	3.17e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HLKPNGBE_02574	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HLKPNGBE_02575	1.05e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
HLKPNGBE_02576	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLKPNGBE_02577	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
HLKPNGBE_02578	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
HLKPNGBE_02579	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
HLKPNGBE_02580	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
HLKPNGBE_02581	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
HLKPNGBE_02582	4.9e-200	-	-	-	S	-	-	-	Alpha beta hydrolase
HLKPNGBE_02583	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_02584	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HLKPNGBE_02586	7.25e-264	yraM	-	-	S	-	-	-	PrpF protein
HLKPNGBE_02587	5.13e-211	yraN	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02588	9.19e-287	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HLKPNGBE_02589	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
HLKPNGBE_02590	1.1e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_02591	9.28e-170	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HLKPNGBE_02593	5.87e-163	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HLKPNGBE_02594	8.73e-191	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLKPNGBE_02595	3.79e-249	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HLKPNGBE_02596	2.66e-215	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HLKPNGBE_02597	1.47e-120	yrdA	-	-	S	-	-	-	DinB family
HLKPNGBE_02598	2.28e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HLKPNGBE_02599	7.37e-133	yrdC	-	-	Q	-	-	-	Isochorismatase family
HLKPNGBE_02600	1.75e-295	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLKPNGBE_02601	1.07e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HLKPNGBE_02602	1.44e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
HLKPNGBE_02603	2.29e-176	azlC	-	-	E	-	-	-	AzlC protein
HLKPNGBE_02604	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HLKPNGBE_02605	2.22e-295	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLKPNGBE_02607	2.08e-209	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HLKPNGBE_02608	1.75e-87	yodA	-	-	S	-	-	-	tautomerase
HLKPNGBE_02609	2.26e-216	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HLKPNGBE_02610	2.58e-255	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HLKPNGBE_02611	1.2e-204	-	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02612	1.53e-219	yrdR	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_02613	7.28e-25	-	-	-	S	-	-	-	YrzO-like protein
HLKPNGBE_02614	1.58e-301	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLKPNGBE_02615	3.73e-109	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HLKPNGBE_02616	1.31e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_02617	2.15e-195	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLKPNGBE_02618	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLKPNGBE_02619	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02620	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HLKPNGBE_02621	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
HLKPNGBE_02622	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
HLKPNGBE_02623	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLKPNGBE_02624	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HLKPNGBE_02625	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HLKPNGBE_02626	6.61e-110	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HLKPNGBE_02628	2.88e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HLKPNGBE_02629	2.36e-291	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HLKPNGBE_02630	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HLKPNGBE_02632	0.0	-	-	-	L	-	-	-	Peptidase, M16
HLKPNGBE_02633	7.55e-280	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
HLKPNGBE_02634	1.07e-300	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HLKPNGBE_02635	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLKPNGBE_02637	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
HLKPNGBE_02638	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
HLKPNGBE_02639	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_02640	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLKPNGBE_02641	3.39e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HLKPNGBE_02642	3.98e-169	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HLKPNGBE_02643	1.57e-180	ywiC	-	-	S	-	-	-	YwiC-like protein
HLKPNGBE_02644	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HLKPNGBE_02645	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLKPNGBE_02646	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HLKPNGBE_02647	6.32e-128	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HLKPNGBE_02648	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HLKPNGBE_02649	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLKPNGBE_02650	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLKPNGBE_02651	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HLKPNGBE_02652	1.32e-57	ywjC	-	-	-	-	-	-	-
HLKPNGBE_02653	4.88e-236	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HLKPNGBE_02654	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HLKPNGBE_02655	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HLKPNGBE_02656	2.1e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
HLKPNGBE_02657	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLKPNGBE_02658	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLKPNGBE_02659	3.31e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HLKPNGBE_02660	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HLKPNGBE_02661	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HLKPNGBE_02662	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLKPNGBE_02663	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLKPNGBE_02664	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HLKPNGBE_02665	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLKPNGBE_02666	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HLKPNGBE_02667	8.53e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HLKPNGBE_02668	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HLKPNGBE_02669	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLKPNGBE_02670	6.26e-119	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HLKPNGBE_02671	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLKPNGBE_02672	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLKPNGBE_02673	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLKPNGBE_02675	1.67e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HLKPNGBE_02676	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HLKPNGBE_02677	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HLKPNGBE_02678	4.44e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLKPNGBE_02679	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HLKPNGBE_02680	5.75e-103	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLKPNGBE_02681	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HLKPNGBE_02682	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HLKPNGBE_02683	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLKPNGBE_02684	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLKPNGBE_02685	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HLKPNGBE_02686	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLKPNGBE_02687	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLKPNGBE_02688	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLKPNGBE_02689	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLKPNGBE_02690	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLKPNGBE_02691	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLKPNGBE_02692	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLKPNGBE_02693	1.04e-76	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLKPNGBE_02694	6.12e-115	ywmA	-	-	-	-	-	-	-
HLKPNGBE_02695	4.54e-45	ywzB	-	-	S	-	-	-	membrane
HLKPNGBE_02696	2.39e-174	ywmB	-	-	S	-	-	-	TATA-box binding
HLKPNGBE_02697	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLKPNGBE_02698	3.72e-238	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HLKPNGBE_02699	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HLKPNGBE_02700	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HLKPNGBE_02702	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HLKPNGBE_02703	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLKPNGBE_02704	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HLKPNGBE_02705	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
HLKPNGBE_02706	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
HLKPNGBE_02708	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HLKPNGBE_02709	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HLKPNGBE_02710	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HLKPNGBE_02711	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02712	1.29e-148	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLKPNGBE_02713	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HLKPNGBE_02714	3.41e-184	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HLKPNGBE_02715	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLKPNGBE_02716	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HLKPNGBE_02717	3.28e-22	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HLKPNGBE_02718	1.55e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HLKPNGBE_02719	2.13e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HLKPNGBE_02720	1.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
HLKPNGBE_02721	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HLKPNGBE_02722	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HLKPNGBE_02723	1.6e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HLKPNGBE_02724	3.04e-102	-	-	-	-	-	-	-	-
HLKPNGBE_02725	2.56e-134	yjgF	-	-	Q	-	-	-	Isochorismatase family
HLKPNGBE_02726	8e-309	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HLKPNGBE_02727	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HLKPNGBE_02728	1.02e-312	ywoF	-	-	P	-	-	-	Right handed beta helix region
HLKPNGBE_02729	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_02730	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
HLKPNGBE_02731	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HLKPNGBE_02732	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HLKPNGBE_02733	6.18e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HLKPNGBE_02734	4.1e-182	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HLKPNGBE_02735	5.45e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HLKPNGBE_02736	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLKPNGBE_02737	1.13e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLKPNGBE_02738	2.55e-197	ywpD	-	-	T	-	-	-	Histidine kinase
HLKPNGBE_02739	4.63e-68	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLKPNGBE_02740	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
HLKPNGBE_02741	5.26e-88	ywpG	-	-	-	-	-	-	-
HLKPNGBE_02742	1.04e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HLKPNGBE_02743	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLKPNGBE_02744	4.53e-203	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HLKPNGBE_02745	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLKPNGBE_02746	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HLKPNGBE_02747	3.6e-25	-	-	-	-	-	-	-	-
HLKPNGBE_02748	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HLKPNGBE_02749	4.51e-156	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HLKPNGBE_02750	3.16e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HLKPNGBE_02751	9.82e-315	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLKPNGBE_02752	2.52e-197	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HLKPNGBE_02754	2.17e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HLKPNGBE_02755	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HLKPNGBE_02756	1.36e-71	-	-	-	S	-	-	-	MORN repeat variant
HLKPNGBE_02757	7.78e-176	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HLKPNGBE_02758	1.16e-209	-	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02759	3.83e-132	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
HLKPNGBE_02761	3.66e-115	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HLKPNGBE_02762	5.52e-133	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HLKPNGBE_02763	4.83e-108	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HLKPNGBE_02764	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HLKPNGBE_02765	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
HLKPNGBE_02766	4.35e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLKPNGBE_02767	2.17e-16	-	-	-	-	-	-	-	-
HLKPNGBE_02768	1.12e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HLKPNGBE_02769	1.02e-196	cotB	-	-	-	ko:K06325	-	ko00000	-
HLKPNGBE_02770	9.09e-164	ywrJ	-	-	-	-	-	-	-
HLKPNGBE_02771	1.68e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLKPNGBE_02772	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
HLKPNGBE_02773	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLKPNGBE_02774	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HLKPNGBE_02775	2.15e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HLKPNGBE_02776	9.2e-64	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
HLKPNGBE_02777	2.49e-122	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HLKPNGBE_02778	1.34e-205	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HLKPNGBE_02779	2.87e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLKPNGBE_02780	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HLKPNGBE_02781	5.6e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLKPNGBE_02782	6.44e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLKPNGBE_02783	2.3e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HLKPNGBE_02784	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HLKPNGBE_02785	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HLKPNGBE_02786	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HLKPNGBE_02787	2.29e-29	ywtC	-	-	-	-	-	-	-
HLKPNGBE_02788	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLKPNGBE_02789	7.24e-205	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HLKPNGBE_02790	1.48e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02791	8.19e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLKPNGBE_02792	2.29e-275	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HLKPNGBE_02793	1.24e-256	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HLKPNGBE_02794	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HLKPNGBE_02795	1.16e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLKPNGBE_02796	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLKPNGBE_02797	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_02798	3.8e-273	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLKPNGBE_02799	1.9e-185	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLKPNGBE_02800	3.82e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HLKPNGBE_02801	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
HLKPNGBE_02802	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLKPNGBE_02803	2.06e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HLKPNGBE_02804	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLKPNGBE_02805	2.13e-127	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLKPNGBE_02806	5.43e-05	-	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase-like
HLKPNGBE_02807	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLKPNGBE_02808	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLKPNGBE_02809	1.78e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLKPNGBE_02810	6.61e-278	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLKPNGBE_02811	2.77e-219	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HLKPNGBE_02812	3.26e-50	-	-	-	-	-	-	-	-
HLKPNGBE_02813	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HLKPNGBE_02814	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HLKPNGBE_02815	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLKPNGBE_02816	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLKPNGBE_02817	8.77e-283	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HLKPNGBE_02818	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLKPNGBE_02819	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HLKPNGBE_02820	6.04e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HLKPNGBE_02821	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HLKPNGBE_02822	3.3e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HLKPNGBE_02823	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HLKPNGBE_02824	3.99e-225	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02825	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HLKPNGBE_02826	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HLKPNGBE_02827	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_02828	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_02829	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HLKPNGBE_02830	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HLKPNGBE_02831	9.99e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HLKPNGBE_02832	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
HLKPNGBE_02833	1.06e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HLKPNGBE_02834	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
HLKPNGBE_02835	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HLKPNGBE_02836	1.97e-199	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HLKPNGBE_02837	4.19e-93	yviE	-	-	-	-	-	-	-
HLKPNGBE_02838	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HLKPNGBE_02839	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HLKPNGBE_02840	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLKPNGBE_02841	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HLKPNGBE_02842	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HLKPNGBE_02843	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HLKPNGBE_02844	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HLKPNGBE_02845	9.14e-88	-	-	-	-	-	-	-	-
HLKPNGBE_02846	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLKPNGBE_02847	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLKPNGBE_02848	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLKPNGBE_02849	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLKPNGBE_02850	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HLKPNGBE_02851	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HLKPNGBE_02852	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HLKPNGBE_02853	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HLKPNGBE_02854	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HLKPNGBE_02855	3.86e-281	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLKPNGBE_02856	5.47e-298	yvkA	-	-	P	-	-	-	-transporter
HLKPNGBE_02857	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02858	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HLKPNGBE_02859	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_02860	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLKPNGBE_02861	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLKPNGBE_02862	2.57e-104	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLKPNGBE_02863	2.73e-46	yvkN	-	-	-	-	-	-	-
HLKPNGBE_02864	8.09e-65	yvlA	-	-	-	-	-	-	-
HLKPNGBE_02865	5.8e-221	yvlB	-	-	S	-	-	-	Putative adhesin
HLKPNGBE_02866	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HLKPNGBE_02867	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HLKPNGBE_02868	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLKPNGBE_02869	6.2e-114	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_02870	2.49e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HLKPNGBE_02871	1.61e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLKPNGBE_02872	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_02873	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HLKPNGBE_02874	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HLKPNGBE_02875	1.39e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLKPNGBE_02876	2.25e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLKPNGBE_02877	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLKPNGBE_02878	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLKPNGBE_02879	3.19e-212	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
HLKPNGBE_02880	4.51e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HLKPNGBE_02881	5.29e-121	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HLKPNGBE_02882	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
HLKPNGBE_02883	2.14e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HLKPNGBE_02884	2.07e-282	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLKPNGBE_02885	9.09e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLKPNGBE_02886	1.19e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLKPNGBE_02887	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HLKPNGBE_02888	7.21e-150	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLKPNGBE_02889	1.44e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLKPNGBE_02890	9.74e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLKPNGBE_02891	2.61e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HLKPNGBE_02892	6.36e-172	-	-	-	-	-	-	-	-
HLKPNGBE_02893	0.0	-	-	-	-	-	-	-	-
HLKPNGBE_02895	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HLKPNGBE_02896	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLKPNGBE_02897	3.05e-190	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HLKPNGBE_02898	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLKPNGBE_02899	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HLKPNGBE_02900	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLKPNGBE_02901	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HLKPNGBE_02902	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLKPNGBE_02903	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HLKPNGBE_02904	5.24e-188	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HLKPNGBE_02905	1.37e-45	-	-	-	-	-	-	-	-
HLKPNGBE_02906	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_02907	1.68e-252	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HLKPNGBE_02908	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_02909	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HLKPNGBE_02910	1.4e-235	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLKPNGBE_02911	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HLKPNGBE_02912	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HLKPNGBE_02913	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HLKPNGBE_02914	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HLKPNGBE_02915	2.28e-223	yvdE	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02916	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HLKPNGBE_02917	1.03e-302	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HLKPNGBE_02918	2.12e-311	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HLKPNGBE_02919	1.18e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HLKPNGBE_02920	2.42e-203	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HLKPNGBE_02921	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HLKPNGBE_02922	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLKPNGBE_02923	1.01e-156	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLKPNGBE_02924	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLKPNGBE_02926	1.99e-235	-	-	-	S	-	-	-	Patatin-like phospholipase
HLKPNGBE_02927	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HLKPNGBE_02928	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
HLKPNGBE_02929	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HLKPNGBE_02930	6.31e-68	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HLKPNGBE_02931	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02932	0.0	ybeC	-	-	E	-	-	-	amino acid
HLKPNGBE_02933	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HLKPNGBE_02934	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HLKPNGBE_02935	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
HLKPNGBE_02936	1.51e-163	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HLKPNGBE_02937	5.1e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HLKPNGBE_02938	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HLKPNGBE_02940	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HLKPNGBE_02941	2.15e-99	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HLKPNGBE_02942	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HLKPNGBE_02943	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HLKPNGBE_02944	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HLKPNGBE_02945	2.95e-286	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HLKPNGBE_02946	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLKPNGBE_02947	7.49e-280	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLKPNGBE_02948	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HLKPNGBE_02949	6.3e-251	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HLKPNGBE_02950	5.09e-264	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HLKPNGBE_02951	4.44e-251	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLKPNGBE_02952	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLKPNGBE_02953	1.65e-141	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLKPNGBE_02954	6.53e-81	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HLKPNGBE_02955	1.2e-284	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HLKPNGBE_02956	1.85e-241	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HLKPNGBE_02957	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
HLKPNGBE_02958	2.57e-308	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HLKPNGBE_02959	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HLKPNGBE_02960	9.32e-145	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HLKPNGBE_02961	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_02962	2.05e-295	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HLKPNGBE_02963	1.3e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HLKPNGBE_02964	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HLKPNGBE_02965	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HLKPNGBE_02966	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HLKPNGBE_02967	1.52e-265	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
HLKPNGBE_02968	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
HLKPNGBE_02969	1.03e-209	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HLKPNGBE_02970	2.48e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HLKPNGBE_02971	1.76e-257	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_02972	7.53e-137	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_02973	5.47e-176	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLKPNGBE_02974	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HLKPNGBE_02975	1.45e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLKPNGBE_02976	2.68e-252	-	-	-	S	-	-	-	Glycosyl hydrolase
HLKPNGBE_02977	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_02978	2.37e-199	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_02979	3.45e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_02980	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_02981	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HLKPNGBE_02982	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLKPNGBE_02983	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLKPNGBE_02984	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLKPNGBE_02985	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HLKPNGBE_02986	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLKPNGBE_02987	1.93e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HLKPNGBE_02988	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HLKPNGBE_02989	1.54e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_02990	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
HLKPNGBE_02994	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HLKPNGBE_02995	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_02996	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HLKPNGBE_02997	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HLKPNGBE_02998	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HLKPNGBE_02999	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HLKPNGBE_03000	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HLKPNGBE_03001	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HLKPNGBE_03002	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HLKPNGBE_03003	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HLKPNGBE_03004	5.29e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLKPNGBE_03005	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HLKPNGBE_03006	1.95e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLKPNGBE_03007	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HLKPNGBE_03008	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HLKPNGBE_03009	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HLKPNGBE_03010	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLKPNGBE_03011	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLKPNGBE_03012	3.07e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLKPNGBE_03013	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
HLKPNGBE_03014	1.91e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLKPNGBE_03016	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
HLKPNGBE_03017	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HLKPNGBE_03018	9.32e-70	ydbL	-	-	-	-	-	-	-
HLKPNGBE_03019	7.34e-160	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLKPNGBE_03020	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03021	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
HLKPNGBE_03022	4.43e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLKPNGBE_03023	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HLKPNGBE_03024	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HLKPNGBE_03025	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HLKPNGBE_03026	1.35e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HLKPNGBE_03027	5.41e-84	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HLKPNGBE_03028	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
HLKPNGBE_03029	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HLKPNGBE_03030	1.06e-190	ydbA	-	-	P	-	-	-	EcsC protein family
HLKPNGBE_03031	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HLKPNGBE_03032	1.67e-42	ydaS	-	-	S	-	-	-	membrane
HLKPNGBE_03033	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLKPNGBE_03034	2.14e-53	-	-	-	-	-	-	-	-
HLKPNGBE_03035	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLKPNGBE_03036	3.75e-103	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HLKPNGBE_03037	0.0	ydaO	-	-	E	-	-	-	amino acid
HLKPNGBE_03038	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HLKPNGBE_03039	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HLKPNGBE_03040	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HLKPNGBE_03041	1.14e-195	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HLKPNGBE_03042	3.08e-267	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HLKPNGBE_03043	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLKPNGBE_03044	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HLKPNGBE_03045	1.88e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HLKPNGBE_03046	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HLKPNGBE_03047	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
HLKPNGBE_03048	6.6e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLKPNGBE_03049	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HLKPNGBE_03050	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_03051	6.05e-129	ydaC	-	-	Q	-	-	-	Methyltransferase domain
HLKPNGBE_03052	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HLKPNGBE_03053	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HLKPNGBE_03054	3.26e-224	ycsN	-	-	S	-	-	-	Oxidoreductase
HLKPNGBE_03055	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HLKPNGBE_03056	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
HLKPNGBE_03058	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HLKPNGBE_03059	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03060	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HLKPNGBE_03061	5.04e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HLKPNGBE_03062	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HLKPNGBE_03063	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HLKPNGBE_03064	9.39e-182	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HLKPNGBE_03065	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLKPNGBE_03067	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HLKPNGBE_03068	2.64e-147	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
HLKPNGBE_03069	6.21e-97	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLKPNGBE_03071	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HLKPNGBE_03072	3.77e-269	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HLKPNGBE_03073	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HLKPNGBE_03074	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HLKPNGBE_03075	1.34e-74	-	-	-	-	-	-	-	-
HLKPNGBE_03076	5.18e-139	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLKPNGBE_03077	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HLKPNGBE_03078	1.07e-138	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_03079	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_03080	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HLKPNGBE_03081	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLKPNGBE_03082	2.4e-313	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLKPNGBE_03083	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLKPNGBE_03084	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLKPNGBE_03085	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
HLKPNGBE_03086	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HLKPNGBE_03087	1.76e-199	ycnC	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03088	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HLKPNGBE_03089	4.98e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HLKPNGBE_03090	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03091	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03092	5.42e-206	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03093	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLKPNGBE_03094	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HLKPNGBE_03096	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HLKPNGBE_03097	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HLKPNGBE_03098	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_03099	5.59e-280	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HLKPNGBE_03100	2.05e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLKPNGBE_03101	2.29e-254	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HLKPNGBE_03102	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HLKPNGBE_03103	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HLKPNGBE_03105	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HLKPNGBE_03106	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HLKPNGBE_03107	5.12e-207	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
HLKPNGBE_03108	3.05e-109	yclD	-	-	-	-	-	-	-
HLKPNGBE_03109	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HLKPNGBE_03110	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HLKPNGBE_03111	2.33e-142	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HLKPNGBE_03112	9.2e-210	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HLKPNGBE_03113	1.5e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HLKPNGBE_03114	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLKPNGBE_03115	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLKPNGBE_03116	3.04e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HLKPNGBE_03117	1.37e-144	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HLKPNGBE_03118	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HLKPNGBE_03119	1.77e-209	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_03120	1.61e-126	-	-	-	S	-	-	-	YcxB-like protein
HLKPNGBE_03121	1.38e-291	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLKPNGBE_03122	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HLKPNGBE_03123	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HLKPNGBE_03124	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_03125	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_03126	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
HLKPNGBE_03127	2.39e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HLKPNGBE_03128	1.38e-127	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HLKPNGBE_03129	6.52e-269	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_03130	4.78e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HLKPNGBE_03131	7.06e-93	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HLKPNGBE_03132	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLKPNGBE_03133	3.53e-69	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HLKPNGBE_03134	5.95e-101	yckC	-	-	S	-	-	-	membrane
HLKPNGBE_03137	3.76e-187	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HLKPNGBE_03138	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLKPNGBE_03139	6.78e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
HLKPNGBE_03140	2.56e-141	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLKPNGBE_03141	1.05e-222	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
HLKPNGBE_03142	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HLKPNGBE_03143	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HLKPNGBE_03144	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLKPNGBE_03145	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HLKPNGBE_03146	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HLKPNGBE_03147	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HLKPNGBE_03148	8.9e-247	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HLKPNGBE_03149	4.74e-209	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HLKPNGBE_03150	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
HLKPNGBE_03151	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
HLKPNGBE_03152	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HLKPNGBE_03153	1.71e-96	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLKPNGBE_03154	4.65e-188	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLKPNGBE_03155	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLKPNGBE_03156	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HLKPNGBE_03157	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HLKPNGBE_03158	1.15e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HLKPNGBE_03159	2.05e-230	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
HLKPNGBE_03160	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HLKPNGBE_03161	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLKPNGBE_03162	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
HLKPNGBE_03163	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLKPNGBE_03164	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HLKPNGBE_03165	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_03166	1.85e-195	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HLKPNGBE_03167	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HLKPNGBE_03168	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_03169	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HLKPNGBE_03170	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HLKPNGBE_03171	2.06e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLKPNGBE_03172	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HLKPNGBE_03173	1.25e-127	ycgB	-	-	-	-	-	-	-
HLKPNGBE_03174	0.0	ycgA	-	-	S	-	-	-	Membrane
HLKPNGBE_03175	2.5e-279	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HLKPNGBE_03176	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HLKPNGBE_03177	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HLKPNGBE_03178	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HLKPNGBE_03179	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLKPNGBE_03180	1.17e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HLKPNGBE_03181	2.32e-279	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HLKPNGBE_03182	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HLKPNGBE_03183	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HLKPNGBE_03184	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HLKPNGBE_03185	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HLKPNGBE_03186	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HLKPNGBE_03187	2.64e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HLKPNGBE_03188	9.18e-242	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_03189	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLKPNGBE_03190	1.99e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLKPNGBE_03191	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLKPNGBE_03192	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLKPNGBE_03193	5.87e-181	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HLKPNGBE_03194	1.42e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HLKPNGBE_03195	3.91e-125	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HLKPNGBE_03196	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_03197	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_03198	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HLKPNGBE_03199	5.83e-223	yccK	-	-	C	-	-	-	Aldo keto reductase
HLKPNGBE_03200	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HLKPNGBE_03201	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLKPNGBE_03202	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLKPNGBE_03203	9.56e-217	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLKPNGBE_03204	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HLKPNGBE_03205	4.32e-78	-	-	-	S	-	-	-	RDD family
HLKPNGBE_03206	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLKPNGBE_03207	8.74e-260	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HLKPNGBE_03208	6.54e-132	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HLKPNGBE_03209	2.87e-308	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HLKPNGBE_03210	3.48e-268	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HLKPNGBE_03211	2.52e-156	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLKPNGBE_03212	7.6e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLKPNGBE_03213	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLKPNGBE_03214	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HLKPNGBE_03215	4.66e-175	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
HLKPNGBE_03216	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HLKPNGBE_03217	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HLKPNGBE_03218	4.25e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
HLKPNGBE_03219	1.66e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03220	1.66e-218	ycbM	-	-	T	-	-	-	Histidine kinase
HLKPNGBE_03221	6.64e-162	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_03222	1.87e-220	eamA1	-	-	EG	-	-	-	spore germination
HLKPNGBE_03223	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HLKPNGBE_03224	4.64e-227	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HLKPNGBE_03225	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HLKPNGBE_03226	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HLKPNGBE_03227	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HLKPNGBE_03228	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_03229	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLKPNGBE_03230	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
HLKPNGBE_03231	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HLKPNGBE_03232	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_03233	9.16e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLKPNGBE_03234	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HLKPNGBE_03235	2.23e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HLKPNGBE_03236	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLKPNGBE_03237	9.84e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HLKPNGBE_03239	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HLKPNGBE_03240	7.72e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLKPNGBE_03241	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03242	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLKPNGBE_03243	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HLKPNGBE_03244	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_03245	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
HLKPNGBE_03246	2.33e-61	ybfN	-	-	-	-	-	-	-
HLKPNGBE_03247	4.33e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HLKPNGBE_03248	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HLKPNGBE_03249	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLKPNGBE_03250	2.02e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLKPNGBE_03252	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HLKPNGBE_03253	5.85e-274	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLKPNGBE_03254	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
HLKPNGBE_03255	5.27e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_03256	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HLKPNGBE_03258	2.36e-287	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_03259	8.93e-220	ybfA	-	-	K	-	-	-	FR47-like protein
HLKPNGBE_03260	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HLKPNGBE_03261	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HLKPNGBE_03262	7.3e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HLKPNGBE_03263	0.0	ybeC	-	-	E	-	-	-	amino acid
HLKPNGBE_03264	1.11e-54	ybyB	-	-	-	-	-	-	-
HLKPNGBE_03265	9.97e-317	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HLKPNGBE_03266	3.86e-195	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
HLKPNGBE_03267	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
HLKPNGBE_03268	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HLKPNGBE_03269	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_03270	1.19e-278	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HLKPNGBE_03271	6.61e-196	ybdN	-	-	-	-	-	-	-
HLKPNGBE_03272	2.49e-181	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HLKPNGBE_03274	4.12e-221	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
HLKPNGBE_03275	2.93e-159	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
HLKPNGBE_03276	8.07e-233	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLKPNGBE_03277	5.88e-103	-	-	-	CO	-	-	-	Thioredoxin-like domain
HLKPNGBE_03278	3.88e-118	-	-	-	C	-	-	-	HEAT repeats
HLKPNGBE_03279	3.99e-313	skfF	-	-	S	-	-	-	ABC transporter
HLKPNGBE_03280	8.07e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLKPNGBE_03281	0.0	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HLKPNGBE_03282	7.24e-304	-	-	-	J	-	-	-	4Fe-4S single cluster domain
HLKPNGBE_03284	1.14e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HLKPNGBE_03285	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
HLKPNGBE_03286	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HLKPNGBE_03287	5.59e-64	-	-	-	-	-	-	-	-
HLKPNGBE_03288	2.51e-125	ybcF	-	-	P	-	-	-	carbonic anhydrase
HLKPNGBE_03289	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
HLKPNGBE_03290	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLKPNGBE_03291	4.49e-130	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLKPNGBE_03292	2.25e-157	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HLKPNGBE_03293	3.67e-227	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLKPNGBE_03294	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLKPNGBE_03295	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLKPNGBE_03296	4.16e-292	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_03297	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLKPNGBE_03298	2.73e-152	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HLKPNGBE_03299	1.6e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_03305	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HLKPNGBE_03306	1.55e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
HLKPNGBE_03307	4.04e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLKPNGBE_03308	3.82e-194	ybbH	-	-	K	-	-	-	transcriptional
HLKPNGBE_03309	7.29e-304	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03310	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HLKPNGBE_03311	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HLKPNGBE_03312	3.6e-306	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_03313	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HLKPNGBE_03314	9.23e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HLKPNGBE_03315	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03316	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03317	4.01e-184	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HLKPNGBE_03318	3.47e-205	ybaS	-	-	S	-	-	-	Na -dependent transporter
HLKPNGBE_03320	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HLKPNGBE_03321	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HLKPNGBE_03322	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
HLKPNGBE_03323	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HLKPNGBE_03324	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HLKPNGBE_03325	1.19e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HLKPNGBE_03326	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
HLKPNGBE_03327	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HLKPNGBE_03328	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HLKPNGBE_03329	1.88e-63	ygaB	-	-	S	-	-	-	YgaB-like protein
HLKPNGBE_03330	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HLKPNGBE_03331	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_03332	1.73e-48	yfhS	-	-	-	-	-	-	-
HLKPNGBE_03333	8.47e-268	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HLKPNGBE_03334	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HLKPNGBE_03335	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HLKPNGBE_03336	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLKPNGBE_03337	3.37e-219	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
HLKPNGBE_03338	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HLKPNGBE_03339	3.58e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HLKPNGBE_03340	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
HLKPNGBE_03341	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
HLKPNGBE_03342	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
HLKPNGBE_03344	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HLKPNGBE_03345	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HLKPNGBE_03346	1.13e-221	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HLKPNGBE_03348	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
HLKPNGBE_03349	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
HLKPNGBE_03350	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
HLKPNGBE_03351	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03352	1.54e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03353	2.81e-233	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLKPNGBE_03354	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLKPNGBE_03355	5.39e-106	yfiV	-	-	K	-	-	-	transcriptional
HLKPNGBE_03356	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HLKPNGBE_03357	2.41e-129	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HLKPNGBE_03358	4.51e-281	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
HLKPNGBE_03359	4.18e-141	yfiR	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03360	2.29e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HLKPNGBE_03361	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLKPNGBE_03362	1.89e-128	padR	-	-	K	-	-	-	transcriptional
HLKPNGBE_03363	4.56e-267	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HLKPNGBE_03364	3.66e-274	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLKPNGBE_03365	3.35e-218	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03366	1.05e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HLKPNGBE_03367	7.54e-276	baeS	-	-	T	-	-	-	Histidine kinase
HLKPNGBE_03369	5.17e-295	-	-	-	S	-	-	-	Oxidoreductase
HLKPNGBE_03370	5.47e-234	-	-	-	G	-	-	-	Xylose isomerase
HLKPNGBE_03371	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLKPNGBE_03372	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
HLKPNGBE_03373	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HLKPNGBE_03374	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
HLKPNGBE_03375	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLKPNGBE_03376	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLKPNGBE_03377	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03378	6.12e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HLKPNGBE_03379	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLKPNGBE_03380	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
HLKPNGBE_03381	1.94e-270	yfjB	-	-	-	-	-	-	-
HLKPNGBE_03382	2.5e-185	yfjC	-	-	-	-	-	-	-
HLKPNGBE_03383	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
HLKPNGBE_03384	1.53e-104	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
HLKPNGBE_03385	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
HLKPNGBE_03386	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HLKPNGBE_03387	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HLKPNGBE_03388	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLKPNGBE_03389	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLKPNGBE_03390	2.75e-244	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLKPNGBE_03391	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLKPNGBE_03393	9.55e-111	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLKPNGBE_03394	1.21e-243	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLKPNGBE_03395	3e-53	-	-	-	S	-	-	-	YfzA-like protein
HLKPNGBE_03396	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLKPNGBE_03397	1.94e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLKPNGBE_03398	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HLKPNGBE_03399	4.82e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HLKPNGBE_03400	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HLKPNGBE_03401	3.26e-36	yfjT	-	-	-	-	-	-	-
HLKPNGBE_03402	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
HLKPNGBE_03403	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HLKPNGBE_03404	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
HLKPNGBE_03405	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HLKPNGBE_03406	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_03407	1.64e-12	-	-	-	-	-	-	-	-
HLKPNGBE_03408	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HLKPNGBE_03409	2.53e-67	yfkI	-	-	S	-	-	-	gas vesicle protein
HLKPNGBE_03410	2.14e-110	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLKPNGBE_03411	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HLKPNGBE_03412	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_03413	8.44e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HLKPNGBE_03414	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLKPNGBE_03415	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
HLKPNGBE_03416	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HLKPNGBE_03417	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLKPNGBE_03418	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03419	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HLKPNGBE_03420	2.28e-271	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
HLKPNGBE_03422	2.19e-249	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
HLKPNGBE_03423	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HLKPNGBE_03424	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HLKPNGBE_03425	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HLKPNGBE_03426	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HLKPNGBE_03427	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HLKPNGBE_03428	3.63e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HLKPNGBE_03429	6.9e-27	yflI	-	-	-	-	-	-	-
HLKPNGBE_03430	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HLKPNGBE_03431	2.51e-159	yflK	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_03432	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HLKPNGBE_03433	1.43e-277	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HLKPNGBE_03434	7.21e-194	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLKPNGBE_03435	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HLKPNGBE_03437	1.45e-232	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HLKPNGBE_03438	3.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLKPNGBE_03439	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HLKPNGBE_03440	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLKPNGBE_03441	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HLKPNGBE_03442	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HLKPNGBE_03443	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HLKPNGBE_03444	2.88e-221	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HLKPNGBE_03445	2.85e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03446	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLKPNGBE_03447	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLKPNGBE_03448	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HLKPNGBE_03449	1.72e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLKPNGBE_03450	4.21e-242	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HLKPNGBE_03451	1.86e-107	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HLKPNGBE_03452	1.86e-266	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HLKPNGBE_03453	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLKPNGBE_03454	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HLKPNGBE_03455	3.03e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HLKPNGBE_03456	6.48e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HLKPNGBE_03457	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLKPNGBE_03458	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
HLKPNGBE_03459	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLKPNGBE_03460	4.16e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HLKPNGBE_03461	9.43e-171	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLKPNGBE_03462	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLKPNGBE_03463	2.84e-244	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HLKPNGBE_03464	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HLKPNGBE_03465	9.79e-232	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HLKPNGBE_03466	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HLKPNGBE_03467	2.15e-190	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HLKPNGBE_03468	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HLKPNGBE_03469	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HLKPNGBE_03470	6.1e-255	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HLKPNGBE_03471	4.77e-270	yetM	-	-	CH	-	-	-	FAD binding domain
HLKPNGBE_03472	6.74e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLKPNGBE_03473	7.35e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_03474	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLKPNGBE_03475	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HLKPNGBE_03476	1.97e-54	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLKPNGBE_03477	3.87e-114	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLKPNGBE_03478	9.79e-45	-	-	-	-	-	-	-	-
HLKPNGBE_03479	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLKPNGBE_03480	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HLKPNGBE_03481	3.13e-158	yetF	-	-	S	-	-	-	membrane
HLKPNGBE_03482	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HLKPNGBE_03483	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLKPNGBE_03484	1.01e-227	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HLKPNGBE_03485	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLKPNGBE_03486	0.0	yetA	-	-	-	-	-	-	-
HLKPNGBE_03487	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HLKPNGBE_03488	9.13e-160	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLKPNGBE_03489	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HLKPNGBE_03490	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HLKPNGBE_03491	3.44e-146	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HLKPNGBE_03492	1.41e-169	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
HLKPNGBE_03493	3.56e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLKPNGBE_03494	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03495	6.85e-255	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HLKPNGBE_03496	1.31e-212	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLKPNGBE_03497	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLKPNGBE_03498	8.76e-316	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLKPNGBE_03499	5.07e-260	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HLKPNGBE_03500	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_03501	3.52e-135	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
HLKPNGBE_03503	1.76e-132	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLKPNGBE_03504	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HLKPNGBE_03505	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HLKPNGBE_03506	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HLKPNGBE_03507	8.81e-206	yesF	-	-	GM	-	-	-	NAD(P)H-binding
HLKPNGBE_03508	4.95e-107	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
HLKPNGBE_03509	1.86e-134	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_03511	1.09e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HLKPNGBE_03513	1.33e-275	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HLKPNGBE_03514	1.73e-246	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
HLKPNGBE_03515	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HLKPNGBE_03516	2.1e-109	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HLKPNGBE_03517	4.15e-42	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
HLKPNGBE_03518	7.48e-05	-	-	-	-	-	-	-	-
HLKPNGBE_03519	1.37e-271	yeeC	-	-	P	-	-	-	T5orf172
HLKPNGBE_03520	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HLKPNGBE_03521	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HLKPNGBE_03522	5.61e-71	-	-	-	L	-	-	-	Resolvase, N terminal domain
HLKPNGBE_03523	3.63e-127	-	-	-	L	-	-	-	Recombinase
HLKPNGBE_03524	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLKPNGBE_03525	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLKPNGBE_03526	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLKPNGBE_03527	2.93e-201	yerO	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03528	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLKPNGBE_03529	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLKPNGBE_03530	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLKPNGBE_03531	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLKPNGBE_03532	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HLKPNGBE_03533	6.28e-253	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HLKPNGBE_03534	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HLKPNGBE_03535	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLKPNGBE_03536	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HLKPNGBE_03537	1.1e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HLKPNGBE_03539	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HLKPNGBE_03540	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_03541	7.03e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HLKPNGBE_03542	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HLKPNGBE_03543	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HLKPNGBE_03544	1.91e-297	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HLKPNGBE_03545	5.26e-96	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HLKPNGBE_03546	2.07e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HLKPNGBE_03547	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HLKPNGBE_03548	4.4e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLKPNGBE_03549	4.2e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HLKPNGBE_03550	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLKPNGBE_03551	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLKPNGBE_03552	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLKPNGBE_03553	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLKPNGBE_03554	1.06e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HLKPNGBE_03555	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLKPNGBE_03556	9.39e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLKPNGBE_03557	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLKPNGBE_03558	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
HLKPNGBE_03559	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HLKPNGBE_03561	1.44e-165	yebC	-	-	M	-	-	-	Membrane
HLKPNGBE_03562	1.2e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLKPNGBE_03563	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLKPNGBE_03564	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HLKPNGBE_03565	6.74e-287	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HLKPNGBE_03566	1.18e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HLKPNGBE_03567	6.13e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLKPNGBE_03568	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HLKPNGBE_03569	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HLKPNGBE_03570	1.9e-233	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
HLKPNGBE_03571	3.21e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HLKPNGBE_03572	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HLKPNGBE_03574	3.76e-213	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HLKPNGBE_03575	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
HLKPNGBE_03576	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HLKPNGBE_03577	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLKPNGBE_03578	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
HLKPNGBE_03579	1.79e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HLKPNGBE_03580	3.96e-177	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HLKPNGBE_03581	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLKPNGBE_03582	5.36e-148	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HLKPNGBE_03583	5.39e-224	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLKPNGBE_03584	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HLKPNGBE_03585	1.06e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HLKPNGBE_03586	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HLKPNGBE_03587	3.73e-11	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
HLKPNGBE_03588	0.0	-	-	-	J	-	-	-	LlaJI restriction endonuclease
HLKPNGBE_03589	3.67e-254	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
HLKPNGBE_03591	1.43e-297	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HLKPNGBE_03592	0.0	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HLKPNGBE_03593	6.93e-88	-	-	-	KL	ko:K06919	-	ko00000	Phage plasmid primase P4 family
HLKPNGBE_03595	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLKPNGBE_03596	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLKPNGBE_03597	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLKPNGBE_03598	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HLKPNGBE_03599	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLKPNGBE_03600	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLKPNGBE_03601	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLKPNGBE_03602	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLKPNGBE_03603	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HLKPNGBE_03604	1.63e-241	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLKPNGBE_03605	1.71e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLKPNGBE_03606	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HLKPNGBE_03607	9.02e-113	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HLKPNGBE_03608	3.06e-237	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HLKPNGBE_03611	1.16e-239	-	-	-	S	-	-	-	A domain family that is part of the cupin metalloenzyme superfamily.
HLKPNGBE_03612	6.59e-111	yxbD	3.2.2.20	-	K	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Acetyltransferase (GNAT) domain
HLKPNGBE_03613	1.21e-315	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLKPNGBE_03614	3.66e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLKPNGBE_03615	4.33e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLKPNGBE_03617	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HLKPNGBE_03618	1.77e-314	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLKPNGBE_03619	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
HLKPNGBE_03621	1.74e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HLKPNGBE_03622	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLKPNGBE_03623	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLKPNGBE_03624	1.46e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HLKPNGBE_03625	2.13e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HLKPNGBE_03626	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HLKPNGBE_03627	4.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HLKPNGBE_03628	1.46e-298	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HLKPNGBE_03629	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HLKPNGBE_03630	1.87e-213	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HLKPNGBE_03631	9.32e-188	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HLKPNGBE_03632	2.43e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HLKPNGBE_03633	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLKPNGBE_03634	4e-233	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_03635	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03636	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HLKPNGBE_03637	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HLKPNGBE_03638	9.01e-228	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLKPNGBE_03639	6.79e-91	-	-	-	-	-	-	-	-
HLKPNGBE_03640	2.66e-28	yxeD	-	-	-	-	-	-	-
HLKPNGBE_03641	7.32e-42	yxeE	-	-	-	-	-	-	-
HLKPNGBE_03644	1.4e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HLKPNGBE_03645	2.17e-243	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HLKPNGBE_03647	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_03648	1.54e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_03649	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLKPNGBE_03650	1.81e-149	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLKPNGBE_03651	1.67e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03652	5.21e-275	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HLKPNGBE_03653	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HLKPNGBE_03654	4.86e-259	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
HLKPNGBE_03655	9.11e-198	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
HLKPNGBE_03656	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLKPNGBE_03657	1.44e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLKPNGBE_03658	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLKPNGBE_03659	4.9e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HLKPNGBE_03660	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLKPNGBE_03661	4.15e-232	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HLKPNGBE_03662	2.44e-303	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HLKPNGBE_03663	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HLKPNGBE_03664	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HLKPNGBE_03665	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HLKPNGBE_03666	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HLKPNGBE_03667	1.88e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HLKPNGBE_03668	2.3e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
HLKPNGBE_03669	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HLKPNGBE_03670	9.25e-103	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
HLKPNGBE_03671	1.33e-67	-	-	-	-	-	-	-	-
HLKPNGBE_03672	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03673	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLKPNGBE_03674	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLKPNGBE_03675	1.17e-216	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HLKPNGBE_03676	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HLKPNGBE_03677	1.09e-94	yxxG	-	-	-	-	-	-	-
HLKPNGBE_03678	3.69e-111	-	-	-	-	-	-	-	-
HLKPNGBE_03679	1.12e-82	-	-	-	-	-	-	-	-
HLKPNGBE_03680	8.76e-99	yxiG	-	-	-	-	-	-	-
HLKPNGBE_03681	1.2e-57	-	-	-	-	-	-	-	-
HLKPNGBE_03682	6.22e-107	-	-	-	-	-	-	-	-
HLKPNGBE_03683	3.79e-125	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
HLKPNGBE_03684	5.53e-65	yxiJ	-	-	S	-	-	-	YxiJ-like protein
HLKPNGBE_03687	3.28e-279	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLKPNGBE_03688	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HLKPNGBE_03689	3.97e-294	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HLKPNGBE_03690	2.75e-145	-	-	-	-	-	-	-	-
HLKPNGBE_03691	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HLKPNGBE_03692	2.62e-185	bglS	-	-	M	-	-	-	licheninase activity
HLKPNGBE_03693	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HLKPNGBE_03694	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HLKPNGBE_03695	9.65e-65	yxiS	-	-	-	-	-	-	-
HLKPNGBE_03696	2.96e-29	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HLKPNGBE_03697	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLKPNGBE_03698	4.24e-186	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HLKPNGBE_03699	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HLKPNGBE_03700	4.65e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLKPNGBE_03701	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLKPNGBE_03702	5.83e-176	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HLKPNGBE_03703	9.77e-279	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HLKPNGBE_03704	7.74e-280	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HLKPNGBE_03705	2.57e-114	yxjI	-	-	S	-	-	-	LURP-one-related
HLKPNGBE_03708	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLKPNGBE_03709	5.66e-150	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
HLKPNGBE_03710	7.13e-261	-	-	-	T	-	-	-	Signal transduction histidine kinase
HLKPNGBE_03711	5.63e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
HLKPNGBE_03712	1.53e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HLKPNGBE_03713	2.01e-123	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLKPNGBE_03714	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLKPNGBE_03715	1.66e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HLKPNGBE_03716	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLKPNGBE_03717	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLKPNGBE_03718	1.16e-211	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HLKPNGBE_03719	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_03720	1.58e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HLKPNGBE_03722	0.0	-	-	-	O	-	-	-	Peptidase family M48
HLKPNGBE_03723	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HLKPNGBE_03724	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HLKPNGBE_03725	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HLKPNGBE_03726	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HLKPNGBE_03727	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HLKPNGBE_03728	2.01e-206	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLKPNGBE_03729	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HLKPNGBE_03730	9.06e-125	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLKPNGBE_03731	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
HLKPNGBE_03732	1.75e-43	-	-	-	-	-	-	-	-
HLKPNGBE_03733	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HLKPNGBE_03734	2.09e-213	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_03735	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLKPNGBE_03736	4.48e-277	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLKPNGBE_03737	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HLKPNGBE_03738	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HLKPNGBE_03739	8.94e-28	yxzF	-	-	-	-	-	-	-
HLKPNGBE_03740	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HLKPNGBE_03741	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HLKPNGBE_03742	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLKPNGBE_03743	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03744	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLKPNGBE_03745	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HLKPNGBE_03746	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_03747	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLKPNGBE_03748	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_03749	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HLKPNGBE_03750	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_03751	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HLKPNGBE_03752	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HLKPNGBE_03753	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HLKPNGBE_03754	2.7e-298	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLKPNGBE_03755	2.15e-115	ywaE	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03756	3.96e-164	ywaF	-	-	S	-	-	-	Integral membrane protein
HLKPNGBE_03757	6.53e-217	gspA	-	-	M	-	-	-	General stress
HLKPNGBE_03758	9.07e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HLKPNGBE_03759	1.45e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03760	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLKPNGBE_03761	9.36e-317	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLKPNGBE_03762	7.78e-165	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HLKPNGBE_03763	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HLKPNGBE_03764	1.3e-283	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HLKPNGBE_03765	1.32e-39	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HLKPNGBE_03766	1.29e-280	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
HLKPNGBE_03767	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HLKPNGBE_03768	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HLKPNGBE_03769	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03770	3.25e-185	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLKPNGBE_03771	7.69e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLKPNGBE_03772	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HLKPNGBE_03773	6.21e-249	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HLKPNGBE_03774	3.23e-310	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HLKPNGBE_03775	1.08e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HLKPNGBE_03776	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLKPNGBE_03777	7.41e-65	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
HLKPNGBE_03779	4.16e-159	ywcC	-	-	K	-	-	-	transcriptional regulator
HLKPNGBE_03780	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
HLKPNGBE_03781	5.56e-291	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLKPNGBE_03782	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HLKPNGBE_03783	5.11e-49	ydaS	-	-	S	-	-	-	membrane
HLKPNGBE_03784	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HLKPNGBE_03785	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLKPNGBE_03786	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HLKPNGBE_03787	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HLKPNGBE_03788	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HLKPNGBE_03789	8.89e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HLKPNGBE_03790	1.98e-179	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HLKPNGBE_03791	4.19e-239	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLKPNGBE_03792	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLKPNGBE_03794	4.49e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HLKPNGBE_03795	2.91e-180	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HLKPNGBE_03796	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLKPNGBE_03797	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HLKPNGBE_03798	6.19e-39	ywdA	-	-	-	-	-	-	-
HLKPNGBE_03799	5.43e-188	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLKPNGBE_03800	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HLKPNGBE_03801	8.74e-146	ywdD	-	-	-	-	-	-	-
HLKPNGBE_03803	5.69e-193	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HLKPNGBE_03804	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLKPNGBE_03805	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLKPNGBE_03806	9.23e-65	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HLKPNGBE_03807	4.57e-304	ywdJ	-	-	F	-	-	-	Xanthine uracil
HLKPNGBE_03808	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
HLKPNGBE_03809	7.61e-114	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HLKPNGBE_03810	4.87e-188	spsA	-	-	M	-	-	-	Spore Coat
HLKPNGBE_03811	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HLKPNGBE_03812	4.54e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HLKPNGBE_03813	1.04e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HLKPNGBE_03814	6.8e-272	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HLKPNGBE_03815	4.64e-169	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HLKPNGBE_03816	2.54e-243	spsG	-	-	M	-	-	-	Spore Coat
HLKPNGBE_03817	2.6e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLKPNGBE_03818	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLKPNGBE_03819	2.44e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLKPNGBE_03820	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HLKPNGBE_03821	1.1e-102	-	-	-	-	-	-	-	-
HLKPNGBE_03822	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLKPNGBE_03823	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLKPNGBE_03824	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HLKPNGBE_03825	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLKPNGBE_03826	1.89e-275	ywfA	-	-	EGP	-	-	-	-transporter
HLKPNGBE_03827	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HLKPNGBE_03828	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HLKPNGBE_03829	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_03830	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HLKPNGBE_03831	1.36e-268	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HLKPNGBE_03832	1.89e-298	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HLKPNGBE_03833	3.52e-178	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HLKPNGBE_03834	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HLKPNGBE_03835	7.1e-226	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HLKPNGBE_03836	9.56e-212	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HLKPNGBE_03837	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HLKPNGBE_03838	1.57e-204	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
HLKPNGBE_03839	5.65e-147	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HLKPNGBE_03840	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HLKPNGBE_03841	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HLKPNGBE_03842	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HLKPNGBE_03843	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_03844	2.66e-307	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HLKPNGBE_03850	1.27e-58	yrkC	-	-	G	-	-	-	Cupin domain
HLKPNGBE_03851	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_03852	2.38e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
HLKPNGBE_03853	2.04e-129	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
HLKPNGBE_03854	2.1e-272	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
HLKPNGBE_03855	1.11e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HLKPNGBE_03856	1.21e-170	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLKPNGBE_03857	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HLKPNGBE_03858	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HLKPNGBE_03859	1.33e-134	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLKPNGBE_03860	7.53e-283	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HLKPNGBE_03861	1.24e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
HLKPNGBE_03862	7.32e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
HLKPNGBE_03863	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
HLKPNGBE_03864	1.42e-78	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_03865	2.25e-131	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HLKPNGBE_03866	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
HLKPNGBE_03868	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
HLKPNGBE_03869	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLKPNGBE_03871	1.27e-134	-	-	-	-	-	-	-	-
HLKPNGBE_03875	9.38e-229	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HLKPNGBE_03876	1.1e-198	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HLKPNGBE_03877	3.33e-159	yqaL	-	-	L	-	-	-	DnaD domain protein
HLKPNGBE_03878	4.9e-214	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HLKPNGBE_03880	1.38e-97	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HLKPNGBE_03881	2.49e-43	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HLKPNGBE_03882	7.56e-214	-	-	-	-	-	-	-	-
HLKPNGBE_03883	1.58e-105	yqaQ	-	-	L	-	-	-	Transposase
HLKPNGBE_03885	2.02e-158	yqaS	-	-	L	-	-	-	DNA packaging
HLKPNGBE_03886	0.0	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HLKPNGBE_03887	0.0	yqbA	-	-	S	-	-	-	portal protein
HLKPNGBE_03888	1.73e-217	-	-	-	S	-	-	-	Phage Mu protein F like protein
HLKPNGBE_03889	2.13e-149	-	-	-	-	-	-	-	-
HLKPNGBE_03890	5.46e-186	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
HLKPNGBE_03891	9.21e-216	xkdG	-	-	S	-	-	-	Phage capsid family
HLKPNGBE_03892	2.47e-68	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
HLKPNGBE_03893	7.09e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HLKPNGBE_03894	7.08e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HLKPNGBE_03895	7.59e-123	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HLKPNGBE_03896	3.24e-102	yqbJ	-	-	-	-	-	-	-
HLKPNGBE_03897	2.52e-36	-	-	-	-	-	-	-	-
HLKPNGBE_03898	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HLKPNGBE_03899	4.23e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HLKPNGBE_03901	9.14e-88	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HLKPNGBE_03902	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HLKPNGBE_03903	6.56e-156	xkdP	-	-	S	-	-	-	Lysin motif
HLKPNGBE_03904	1.02e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
HLKPNGBE_03905	6.68e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HLKPNGBE_03906	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HLKPNGBE_03907	1.31e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HLKPNGBE_03908	4.58e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HLKPNGBE_03909	3e-54	-	-	-	-	-	-	-	-
HLKPNGBE_03910	2.91e-283	-	-	-	-	-	-	-	-
HLKPNGBE_03911	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
HLKPNGBE_03912	9.34e-33	-	-	-	-	-	-	-	-
HLKPNGBE_03913	2.45e-213	xepA	-	-	-	-	-	-	-
HLKPNGBE_03914	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
HLKPNGBE_03915	9.72e-187	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HLKPNGBE_03917	5.4e-80	-	-	-	-	-	-	-	-
HLKPNGBE_03919	1.66e-136	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
HLKPNGBE_03920	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HLKPNGBE_03923	8.68e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLKPNGBE_03924	2.08e-197	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HLKPNGBE_03925	1.53e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
HLKPNGBE_03926	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLKPNGBE_03927	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
HLKPNGBE_03928	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HLKPNGBE_03929	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HLKPNGBE_03930	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLKPNGBE_03931	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HLKPNGBE_03932	9.38e-171	-	-	-	-	-	-	-	-
HLKPNGBE_03933	7.95e-219	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
HLKPNGBE_03934	3.97e-136	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HLKPNGBE_03935	7.45e-180	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HLKPNGBE_03936	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLKPNGBE_03938	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HLKPNGBE_03939	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HLKPNGBE_03940	8.44e-201	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLKPNGBE_03941	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HLKPNGBE_03942	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLKPNGBE_03943	4.81e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HLKPNGBE_03944	9.76e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLKPNGBE_03945	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HLKPNGBE_03946	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLKPNGBE_03947	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HLKPNGBE_03948	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HLKPNGBE_03949	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HLKPNGBE_03950	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
HLKPNGBE_03951	2.01e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLKPNGBE_03952	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLKPNGBE_03953	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HLKPNGBE_03954	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HLKPNGBE_03955	6.28e-73	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HLKPNGBE_03956	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLKPNGBE_03957	4.3e-278	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HLKPNGBE_03958	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLKPNGBE_03959	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLKPNGBE_03960	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLKPNGBE_03961	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLKPNGBE_03962	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HLKPNGBE_03963	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLKPNGBE_03964	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HLKPNGBE_03965	3.45e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HLKPNGBE_03966	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HLKPNGBE_03967	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HLKPNGBE_03968	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HLKPNGBE_03969	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
HLKPNGBE_03970	3.13e-79	yqfB	-	-	-	-	-	-	-
HLKPNGBE_03971	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HLKPNGBE_03972	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HLKPNGBE_03973	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HLKPNGBE_03975	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HLKPNGBE_03976	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLKPNGBE_03977	1.42e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HLKPNGBE_03978	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HLKPNGBE_03979	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLKPNGBE_03980	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
HLKPNGBE_03981	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLKPNGBE_03982	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HLKPNGBE_03983	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HLKPNGBE_03984	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
HLKPNGBE_03985	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLKPNGBE_03986	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HLKPNGBE_03987	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLKPNGBE_03988	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLKPNGBE_03989	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HLKPNGBE_03990	2.41e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HLKPNGBE_03991	2.27e-270	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLKPNGBE_03992	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HLKPNGBE_03993	4.89e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HLKPNGBE_03994	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLKPNGBE_03995	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLKPNGBE_03996	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HLKPNGBE_03997	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLKPNGBE_03998	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HLKPNGBE_03999	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HLKPNGBE_04000	2.04e-81	yqfX	-	-	S	-	-	-	membrane
HLKPNGBE_04001	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HLKPNGBE_04002	2.84e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HLKPNGBE_04003	2.05e-99	yqgA	-	-	-	-	-	-	-
HLKPNGBE_04004	9.27e-172	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HLKPNGBE_04005	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HLKPNGBE_04006	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HLKPNGBE_04007	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HLKPNGBE_04008	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HLKPNGBE_04009	4.51e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLKPNGBE_04010	7.43e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLKPNGBE_04011	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HLKPNGBE_04012	2.4e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLKPNGBE_04013	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLKPNGBE_04014	2.92e-98	yqzC	-	-	S	-	-	-	YceG-like family
HLKPNGBE_04015	3.42e-68	yqzD	-	-	-	-	-	-	-
HLKPNGBE_04017	1.24e-260	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
HLKPNGBE_04018	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLKPNGBE_04019	2.38e-138	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLKPNGBE_04020	3.38e-14	yqgO	-	-	-	-	-	-	-
HLKPNGBE_04021	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HLKPNGBE_04022	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HLKPNGBE_04023	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HLKPNGBE_04024	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HLKPNGBE_04025	1.06e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HLKPNGBE_04026	5.65e-258	yqgU	-	-	-	-	-	-	-
HLKPNGBE_04027	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HLKPNGBE_04028	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HLKPNGBE_04029	5.52e-158	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HLKPNGBE_04030	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HLKPNGBE_04031	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HLKPNGBE_04033	1.06e-193	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLKPNGBE_04034	8.56e-307	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLKPNGBE_04035	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HLKPNGBE_04037	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLKPNGBE_04038	1.29e-220	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HLKPNGBE_04039	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HLKPNGBE_04040	9.7e-94	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
HLKPNGBE_04041	4.35e-79	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HLKPNGBE_04042	3.44e-65	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HLKPNGBE_04043	2.55e-55	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HLKPNGBE_04044	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
HLKPNGBE_04045	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HLKPNGBE_04046	8.73e-160	yqxM	-	-	-	ko:K19433	-	ko00000	-
HLKPNGBE_04047	7.4e-98	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HLKPNGBE_04048	1.56e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HLKPNGBE_04049	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HLKPNGBE_04050	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HLKPNGBE_04051	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HLKPNGBE_04052	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLKPNGBE_04053	8.13e-263	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HLKPNGBE_04054	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLKPNGBE_04055	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLKPNGBE_04056	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HLKPNGBE_04057	1.12e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HLKPNGBE_04058	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HLKPNGBE_04059	1.21e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HLKPNGBE_04060	5.18e-81	yqhP	-	-	-	-	-	-	-
HLKPNGBE_04061	3.79e-223	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HLKPNGBE_04062	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HLKPNGBE_04063	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HLKPNGBE_04064	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HLKPNGBE_04065	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLKPNGBE_04066	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HLKPNGBE_04067	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HLKPNGBE_04068	6.93e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HLKPNGBE_04069	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HLKPNGBE_04070	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HLKPNGBE_04071	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HLKPNGBE_04072	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HLKPNGBE_04073	9.25e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HLKPNGBE_04074	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HLKPNGBE_04075	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLKPNGBE_04078	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HLKPNGBE_04079	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
HLKPNGBE_04080	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HLKPNGBE_04081	4.06e-110	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HLKPNGBE_04082	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
HLKPNGBE_04083	8.58e-139	yuaD	-	-	-	-	-	-	-
HLKPNGBE_04084	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HLKPNGBE_04085	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLKPNGBE_04086	3.53e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HLKPNGBE_04087	5.83e-118	yuaB	-	-	-	-	-	-	-
HLKPNGBE_04088	1.83e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HLKPNGBE_04089	1.85e-301	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
HLKPNGBE_04090	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
HLKPNGBE_04091	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLKPNGBE_04092	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HLKPNGBE_04093	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
HLKPNGBE_04095	6.02e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLKPNGBE_04096	3.8e-256	yubA	-	-	S	-	-	-	transporter activity
HLKPNGBE_04097	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HLKPNGBE_04098	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HLKPNGBE_04099	4.94e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HLKPNGBE_04100	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HLKPNGBE_04101	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLKPNGBE_04102	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
HLKPNGBE_04103	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_04104	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_04105	6.34e-300	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_04106	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLKPNGBE_04107	1.06e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HLKPNGBE_04108	5e-48	-	-	-	-	-	-	-	-
HLKPNGBE_04109	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HLKPNGBE_04110	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLKPNGBE_04111	1.07e-301	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLKPNGBE_04112	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HLKPNGBE_04113	1.35e-51	-	-	-	-	-	-	-	-
HLKPNGBE_04114	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HLKPNGBE_04115	1.76e-233	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HLKPNGBE_04116	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
HLKPNGBE_04118	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLKPNGBE_04119	5.56e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HLKPNGBE_04120	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HLKPNGBE_04121	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HLKPNGBE_04122	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HLKPNGBE_04123	6.62e-256	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HLKPNGBE_04124	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
HLKPNGBE_04125	1.2e-201	yugF	-	-	I	-	-	-	Hydrolase
HLKPNGBE_04126	6.7e-56	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HLKPNGBE_04127	2.09e-289	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HLKPNGBE_04128	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_04129	4.3e-92	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HLKPNGBE_04130	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HLKPNGBE_04132	1.96e-245	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HLKPNGBE_04133	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HLKPNGBE_04134	3.31e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_04135	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HLKPNGBE_04136	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HLKPNGBE_04137	1.14e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HLKPNGBE_04138	6.34e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HLKPNGBE_04139	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLKPNGBE_04140	1.57e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLKPNGBE_04141	1.47e-216	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLKPNGBE_04142	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
HLKPNGBE_04143	7.06e-22	-	-	-	-	-	-	-	-
HLKPNGBE_04144	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLKPNGBE_04145	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLKPNGBE_04146	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLKPNGBE_04147	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLKPNGBE_04148	7.39e-103	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLKPNGBE_04149	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLKPNGBE_04150	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HLKPNGBE_04151	3.18e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HLKPNGBE_04152	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLKPNGBE_04153	4.23e-276	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_04154	3.27e-246	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLKPNGBE_04156	1.4e-209	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
HLKPNGBE_04157	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
HLKPNGBE_04158	9.63e-08	-	-	-	-	-	-	-	-
HLKPNGBE_04159	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HLKPNGBE_04160	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLKPNGBE_04161	5.65e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HLKPNGBE_04162	1.32e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLKPNGBE_04163	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
HLKPNGBE_04164	1.23e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HLKPNGBE_04165	4.72e-245	yueF	-	-	S	-	-	-	transporter activity
HLKPNGBE_04166	3.97e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
HLKPNGBE_04167	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HLKPNGBE_04168	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HLKPNGBE_04169	6.1e-171	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLKPNGBE_04170	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HLKPNGBE_04171	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HLKPNGBE_04172	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HLKPNGBE_04173	4.28e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HLKPNGBE_04174	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HLKPNGBE_04175	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HLKPNGBE_04176	1.03e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
HLKPNGBE_04177	4.9e-263	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HLKPNGBE_04178	2.07e-169	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HLKPNGBE_04179	1.42e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HLKPNGBE_04180	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLKPNGBE_04181	3.83e-229	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HLKPNGBE_04182	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HLKPNGBE_04183	7.34e-291	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HLKPNGBE_04184	1.43e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLKPNGBE_04185	1.55e-213	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HLKPNGBE_04186	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HLKPNGBE_04187	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HLKPNGBE_04188	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HLKPNGBE_04189	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HLKPNGBE_04190	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HLKPNGBE_04191	1.69e-151	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_04192	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
HLKPNGBE_04193	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLKPNGBE_04194	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HLKPNGBE_04196	1.15e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLKPNGBE_04197	2.96e-151	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
HLKPNGBE_04198	6.88e-116	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLKPNGBE_04199	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HLKPNGBE_04200	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLKPNGBE_04201	1.54e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLKPNGBE_04202	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HLKPNGBE_04203	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLKPNGBE_04204	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_04205	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HLKPNGBE_04206	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HLKPNGBE_04207	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLKPNGBE_04208	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HLKPNGBE_04209	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HLKPNGBE_04210	4.63e-255	yutH	-	-	S	-	-	-	Spore coat protein
HLKPNGBE_04211	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HLKPNGBE_04212	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLKPNGBE_04213	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HLKPNGBE_04214	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
HLKPNGBE_04215	9.45e-145	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLKPNGBE_04216	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HLKPNGBE_04217	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HLKPNGBE_04218	4.25e-172	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HLKPNGBE_04219	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HLKPNGBE_04220	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLKPNGBE_04221	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLKPNGBE_04222	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HLKPNGBE_04223	2.72e-82	yunG	-	-	-	-	-	-	-
HLKPNGBE_04224	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HLKPNGBE_04225	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HLKPNGBE_04226	1.46e-300	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
HLKPNGBE_04227	1.65e-285	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HLKPNGBE_04228	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HLKPNGBE_04229	1.41e-79	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HLKPNGBE_04230	1.3e-126	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HLKPNGBE_04231	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HLKPNGBE_04232	4.85e-194	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HLKPNGBE_04233	2.62e-144	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HLKPNGBE_04234	5.12e-243	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HLKPNGBE_04236	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HLKPNGBE_04237	4.9e-303	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HLKPNGBE_04238	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
HLKPNGBE_04239	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLKPNGBE_04240	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HLKPNGBE_04241	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HLKPNGBE_04242	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HLKPNGBE_04243	1.24e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLKPNGBE_04244	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HLKPNGBE_04245	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HLKPNGBE_04246	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HLKPNGBE_04247	1.42e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HLKPNGBE_04249	3.35e-56	-	-	-	-	-	-	-	-
HLKPNGBE_04250	2.14e-87	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily