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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IEAAGIAC_00001	1.48e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEAAGIAC_00002	4.78e-90	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEAAGIAC_00004	2.5e-278	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
IEAAGIAC_00005	7.8e-266	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IEAAGIAC_00006	4.38e-210	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IEAAGIAC_00007	9.97e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IEAAGIAC_00008	2.53e-242	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IEAAGIAC_00009	2.42e-80	-	-	-	K	-	-	-	Putative DNA-binding domain
IEAAGIAC_00010	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IEAAGIAC_00011	9.75e-186	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IEAAGIAC_00012	3.05e-56	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IEAAGIAC_00013	1.82e-102	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
IEAAGIAC_00016	1.38e-12	-	-	-	-	-	-	-	-
IEAAGIAC_00018	4.65e-91	-	-	-	S	-	-	-	HIRAN
IEAAGIAC_00019	2.63e-180	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
IEAAGIAC_00021	8.68e-144	-	-	-	-	-	-	-	-
IEAAGIAC_00022	2.99e-103	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IEAAGIAC_00023	1.37e-63	-	-	-	-	-	-	-	-
IEAAGIAC_00024	2.87e-88	-	-	-	-	-	-	-	-
IEAAGIAC_00025	7.79e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1828
IEAAGIAC_00026	1.41e-157	-	-	-	S	-	-	-	Rib/alpha-like repeat
IEAAGIAC_00027	2.03e-09	-	-	-	-	-	-	-	-
IEAAGIAC_00028	2.05e-312	yagE	-	-	E	-	-	-	amino acid
IEAAGIAC_00029	3.17e-149	-	-	-	GM	-	-	-	NmrA-like family
IEAAGIAC_00030	1.11e-193	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IEAAGIAC_00031	6.13e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
IEAAGIAC_00032	1.43e-222	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
IEAAGIAC_00033	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IEAAGIAC_00034	1.79e-304	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IEAAGIAC_00035	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IEAAGIAC_00036	1.96e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IEAAGIAC_00037	7.14e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IEAAGIAC_00038	8.03e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IEAAGIAC_00039	4.54e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IEAAGIAC_00040	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IEAAGIAC_00041	7.45e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IEAAGIAC_00042	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IEAAGIAC_00043	1.69e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IEAAGIAC_00044	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IEAAGIAC_00045	9.56e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IEAAGIAC_00046	5.56e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IEAAGIAC_00047	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
IEAAGIAC_00048	1.23e-172	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEAAGIAC_00049	1.59e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEAAGIAC_00050	4.82e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IEAAGIAC_00051	4.97e-98	-	-	-	M	-	-	-	Lysin motif
IEAAGIAC_00052	7.74e-124	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEAAGIAC_00053	3.58e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IEAAGIAC_00054	6.93e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IEAAGIAC_00055	1.28e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IEAAGIAC_00056	1.37e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEAAGIAC_00057	1.21e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IEAAGIAC_00058	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
IEAAGIAC_00060	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IEAAGIAC_00061	9.23e-110	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IEAAGIAC_00062	1.07e-185	-	-	-	S	-	-	-	KAP family P-loop domain
IEAAGIAC_00063	1.28e-38	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IEAAGIAC_00064	2.69e-19	-	-	-	M	-	-	-	LysM domain
IEAAGIAC_00065	1.06e-11	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IEAAGIAC_00066	2.16e-183	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IEAAGIAC_00067	3.24e-07	-	-	-	J	ko:K10716	-	ko00000,ko02000	Ion transport protein
IEAAGIAC_00068	0.0	-	-	-	C	-	-	-	FMN_bind
IEAAGIAC_00069	1.46e-109	-	-	-	-	-	-	-	-
IEAAGIAC_00070	2.58e-54	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IEAAGIAC_00071	2.62e-44	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
IEAAGIAC_00072	4.7e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEAAGIAC_00073	1.17e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IEAAGIAC_00074	2.78e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IEAAGIAC_00075	7.4e-193	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IEAAGIAC_00076	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IEAAGIAC_00077	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IEAAGIAC_00078	1.41e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEAAGIAC_00079	1.73e-169	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEAAGIAC_00080	3.42e-196	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IEAAGIAC_00081	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEAAGIAC_00082	5.88e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IEAAGIAC_00083	1.42e-217	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IEAAGIAC_00084	1.9e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IEAAGIAC_00085	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IEAAGIAC_00086	2.39e-228	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IEAAGIAC_00087	1.08e-123	-	-	-	K	-	-	-	LysR substrate binding domain
IEAAGIAC_00088	5.82e-130	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IEAAGIAC_00090	7.15e-94	-	-	-	-	-	-	-	-
IEAAGIAC_00091	1.93e-266	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IEAAGIAC_00092	1.23e-67	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IEAAGIAC_00093	4.3e-131	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IEAAGIAC_00095	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IEAAGIAC_00096	1.2e-105	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
IEAAGIAC_00097	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IEAAGIAC_00098	5.42e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IEAAGIAC_00099	5.28e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IEAAGIAC_00100	3.5e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
IEAAGIAC_00101	1.02e-18	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IEAAGIAC_00102	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IEAAGIAC_00103	4.36e-143	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IEAAGIAC_00104	2e-15	-	-	-	S	-	-	-	reductase
IEAAGIAC_00105	1.47e-75	-	-	-	S	-	-	-	reductase
IEAAGIAC_00106	3.6e-139	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
IEAAGIAC_00107	1.41e-149	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IEAAGIAC_00108	5.04e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
IEAAGIAC_00109	9.75e-311	-	-	-	T	-	-	-	GHKL domain
IEAAGIAC_00110	3.17e-116	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IEAAGIAC_00111	2.98e-132	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IEAAGIAC_00112	1.87e-65	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IEAAGIAC_00113	4.3e-130	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IEAAGIAC_00114	8.28e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IEAAGIAC_00115	1.43e-42	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEAAGIAC_00116	2.14e-232	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IEAAGIAC_00117	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IEAAGIAC_00118	1.75e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IEAAGIAC_00119	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IEAAGIAC_00120	7.42e-244	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IEAAGIAC_00121	1.43e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEAAGIAC_00122	2.39e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IEAAGIAC_00123	6.37e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IEAAGIAC_00124	3.23e-248	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEAAGIAC_00125	1.96e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IEAAGIAC_00126	2.73e-283	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IEAAGIAC_00127	2.05e-295	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEAAGIAC_00128	1.15e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IEAAGIAC_00129	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IEAAGIAC_00130	3.57e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IEAAGIAC_00131	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IEAAGIAC_00132	5.25e-178	-	-	-	H	-	-	-	Nodulation protein S (NodS)
IEAAGIAC_00133	0.000705	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IEAAGIAC_00134	7.52e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEAAGIAC_00135	1.2e-20	-	-	-	S	-	-	-	PFAM Archaeal ATPase
IEAAGIAC_00137	2.24e-176	-	-	-	S	-	-	-	PFAM Archaeal ATPase
IEAAGIAC_00138	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
IEAAGIAC_00140	9.35e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IEAAGIAC_00141	4.08e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IEAAGIAC_00142	2.2e-101	-	-	-	S	-	-	-	Cupin domain
IEAAGIAC_00143	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IEAAGIAC_00144	4.59e-93	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
IEAAGIAC_00145	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IEAAGIAC_00146	8.47e-202	-	-	-	C	-	-	-	Aldo keto reductase
IEAAGIAC_00147	2.98e-23	lysR	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00148	1.25e-300	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
IEAAGIAC_00149	7.93e-220	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IEAAGIAC_00150	3.74e-44	-	-	-	-	-	-	-	-
IEAAGIAC_00151	4.83e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IEAAGIAC_00152	3.63e-249	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IEAAGIAC_00153	9.06e-297	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IEAAGIAC_00154	2.81e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IEAAGIAC_00155	3.62e-212	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IEAAGIAC_00156	5.54e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IEAAGIAC_00157	1.89e-148	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEAAGIAC_00158	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEAAGIAC_00159	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEAAGIAC_00160	6.88e-230	-	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00161	4.97e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IEAAGIAC_00162	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IEAAGIAC_00163	9.62e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEAAGIAC_00164	3.13e-158	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IEAAGIAC_00165	9.43e-259	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IEAAGIAC_00166	5.42e-175	lysR	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00167	3.06e-193	-	-	-	-	-	-	-	-
IEAAGIAC_00168	5.3e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
IEAAGIAC_00169	2.56e-82	-	-	-	-	-	-	-	-
IEAAGIAC_00170	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IEAAGIAC_00171	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IEAAGIAC_00172	2.99e-248	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IEAAGIAC_00173	1.95e-218	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IEAAGIAC_00174	7.17e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IEAAGIAC_00175	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IEAAGIAC_00176	7.27e-73	-	-	-	-	-	-	-	-
IEAAGIAC_00177	1.38e-224	degV1	-	-	S	-	-	-	DegV family
IEAAGIAC_00178	1.62e-280	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IEAAGIAC_00179	2.52e-304	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IEAAGIAC_00180	1.27e-272	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IEAAGIAC_00181	2.77e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IEAAGIAC_00182	2.2e-134	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IEAAGIAC_00183	5.29e-148	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IEAAGIAC_00184	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IEAAGIAC_00185	1.51e-145	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEAAGIAC_00186	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IEAAGIAC_00187	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IEAAGIAC_00188	2.19e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IEAAGIAC_00189	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IEAAGIAC_00190	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IEAAGIAC_00191	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IEAAGIAC_00192	4.55e-213	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
IEAAGIAC_00193	5.58e-222	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IEAAGIAC_00194	4.33e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IEAAGIAC_00195	1.24e-235	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IEAAGIAC_00196	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_00197	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_00198	3.49e-289	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IEAAGIAC_00199	1.71e-13	rnhA	3.1.26.4	-	L	ko:K03469,ko:K06993	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Caulimovirus viroplasmin
IEAAGIAC_00200	7.11e-260	-	-	-	G	-	-	-	Transmembrane secretion effector
IEAAGIAC_00201	5.51e-200	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
IEAAGIAC_00202	5.97e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
IEAAGIAC_00203	3.94e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IEAAGIAC_00204	7.5e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEAAGIAC_00205	3.61e-110	-	-	-	S	-	-	-	ASCH
IEAAGIAC_00206	4.87e-190	-	-	-	F	-	-	-	Phosphorylase superfamily
IEAAGIAC_00207	5.66e-184	-	-	-	F	-	-	-	Phosphorylase superfamily
IEAAGIAC_00208	1.16e-148	-	-	-	F	-	-	-	Phosphorylase superfamily
IEAAGIAC_00209	9.45e-104	-	-	-	F	-	-	-	NUDIX domain
IEAAGIAC_00210	5.15e-208	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
IEAAGIAC_00211	5.27e-71	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
IEAAGIAC_00212	4.11e-118	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IEAAGIAC_00213	3.24e-19	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IEAAGIAC_00214	3.18e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IEAAGIAC_00215	9.24e-114	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
IEAAGIAC_00216	4.55e-117	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IEAAGIAC_00217	1.5e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
IEAAGIAC_00218	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEAAGIAC_00219	3.11e-57	-	-	-	-	-	-	-	-
IEAAGIAC_00220	1.28e-156	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IEAAGIAC_00221	1.32e-80	-	-	-	-	-	-	-	-
IEAAGIAC_00222	1.26e-61	-	-	-	S	-	-	-	MazG-like family
IEAAGIAC_00223	4.7e-108	-	-	-	FG	-	-	-	HIT domain
IEAAGIAC_00224	1.15e-53	-	-	-	-	-	-	-	-
IEAAGIAC_00226	2.95e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IEAAGIAC_00227	5.9e-103	-	-	-	-	-	-	-	-
IEAAGIAC_00228	1.29e-139	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IEAAGIAC_00229	2.01e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
IEAAGIAC_00230	8.69e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
IEAAGIAC_00231	1.59e-64	-	-	-	-	-	-	-	-
IEAAGIAC_00232	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IEAAGIAC_00233	4.09e-101	yfhC	-	-	C	-	-	-	nitroreductase
IEAAGIAC_00234	1.68e-257	-	-	-	P	-	-	-	Major Facilitator Superfamily
IEAAGIAC_00235	2.03e-310	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEAAGIAC_00237	5.44e-102	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
IEAAGIAC_00238	5.15e-79	-	-	-	-	-	-	-	-
IEAAGIAC_00239	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_00240	4.92e-230	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
IEAAGIAC_00241	1.21e-188	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
IEAAGIAC_00242	3.52e-15	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IEAAGIAC_00243	9.45e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IEAAGIAC_00244	1.33e-212	-	-	-	C	-	-	-	Oxidoreductase
IEAAGIAC_00245	2.22e-145	-	-	-	C	-	-	-	nitroreductase
IEAAGIAC_00246	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IEAAGIAC_00247	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00248	7.74e-147	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00249	2.23e-138	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
IEAAGIAC_00250	2.95e-262	-	-	-	M	-	-	-	Glycosyl transferases group 1
IEAAGIAC_00251	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IEAAGIAC_00252	3.15e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
IEAAGIAC_00253	1.33e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEAAGIAC_00254	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IEAAGIAC_00255	1.64e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IEAAGIAC_00256	1.19e-296	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IEAAGIAC_00257	2.04e-227	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IEAAGIAC_00258	6.13e-119	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEAAGIAC_00259	6.47e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IEAAGIAC_00260	2.91e-165	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IEAAGIAC_00261	3.18e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEAAGIAC_00262	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IEAAGIAC_00263	4.3e-189	yxeH	-	-	S	-	-	-	hydrolase
IEAAGIAC_00264	6.25e-227	-	-	-	S	-	-	-	DUF218 domain
IEAAGIAC_00265	3.43e-66	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
IEAAGIAC_00266	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IEAAGIAC_00267	8.88e-221	-	-	-	-	-	-	-	-
IEAAGIAC_00268	1.81e-167	-	-	-	-	-	-	-	-
IEAAGIAC_00269	7.06e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IEAAGIAC_00270	5.06e-31	-	-	-	-	-	-	-	-
IEAAGIAC_00271	8.76e-177	-	-	-	-	-	-	-	-
IEAAGIAC_00272	4.59e-182	-	-	-	-	-	-	-	-
IEAAGIAC_00273	4.44e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IEAAGIAC_00274	4.24e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IEAAGIAC_00275	5.38e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IEAAGIAC_00276	1.35e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEAAGIAC_00277	3.7e-155	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IEAAGIAC_00278	4.82e-193	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IEAAGIAC_00279	1.81e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00280	7.1e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00281	6.84e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
IEAAGIAC_00282	8.64e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IEAAGIAC_00283	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IEAAGIAC_00284	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IEAAGIAC_00285	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IEAAGIAC_00286	5.64e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IEAAGIAC_00287	6.75e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEAAGIAC_00288	1.45e-115	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IEAAGIAC_00289	1.09e-223	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IEAAGIAC_00290	5.18e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IEAAGIAC_00291	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IEAAGIAC_00292	5.7e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IEAAGIAC_00293	2.96e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IEAAGIAC_00294	2.89e-194	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IEAAGIAC_00295	3.7e-156	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IEAAGIAC_00296	3.17e-202	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEAAGIAC_00297	1.28e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEAAGIAC_00298	4.55e-12	-	-	-	-	-	-	-	-
IEAAGIAC_00299	1.69e-182	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IEAAGIAC_00300	6.34e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IEAAGIAC_00301	6.43e-283	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IEAAGIAC_00303	1.16e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
IEAAGIAC_00304	1.28e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IEAAGIAC_00305	1.11e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IEAAGIAC_00306	6.11e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IEAAGIAC_00307	3.38e-109	-	-	-	-	-	-	-	-
IEAAGIAC_00308	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IEAAGIAC_00309	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IEAAGIAC_00310	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IEAAGIAC_00311	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IEAAGIAC_00312	6.16e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEAAGIAC_00313	6.22e-134	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IEAAGIAC_00314	5.16e-291	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IEAAGIAC_00315	5.59e-288	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
IEAAGIAC_00316	2.23e-233	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
IEAAGIAC_00317	4.51e-256	-	-	-	D	-	-	-	transport
IEAAGIAC_00318	2.37e-97	-	-	-	D	-	-	-	transport
IEAAGIAC_00319	6.31e-173	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IEAAGIAC_00320	1.41e-213	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IEAAGIAC_00321	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEAAGIAC_00322	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IEAAGIAC_00323	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IEAAGIAC_00324	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IEAAGIAC_00325	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IEAAGIAC_00326	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IEAAGIAC_00327	4.33e-95	-	-	-	-	-	-	-	-
IEAAGIAC_00328	1.17e-175	-	-	-	-	-	-	-	-
IEAAGIAC_00329	3.41e-37	-	-	-	-	-	-	-	-
IEAAGIAC_00330	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IEAAGIAC_00331	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEAAGIAC_00332	4.99e-301	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IEAAGIAC_00333	1.13e-184	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IEAAGIAC_00334	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IEAAGIAC_00335	1.96e-226	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IEAAGIAC_00336	1.09e-177	-	-	-	-	-	-	-	-
IEAAGIAC_00337	3.82e-190	-	-	-	-	-	-	-	-
IEAAGIAC_00338	8.06e-96	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IEAAGIAC_00339	2.23e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEAAGIAC_00340	9.46e-63	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
IEAAGIAC_00341	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEAAGIAC_00342	2.27e-93	-	-	-	S	-	-	-	GtrA-like protein
IEAAGIAC_00343	7.4e-226	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IEAAGIAC_00344	1.03e-150	-	-	-	-	-	-	-	-
IEAAGIAC_00345	3.83e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IEAAGIAC_00346	9.65e-218	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
IEAAGIAC_00347	1.08e-266	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IEAAGIAC_00348	8.12e-144	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEAAGIAC_00349	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
IEAAGIAC_00350	3.08e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEAAGIAC_00352	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IEAAGIAC_00353	5.69e-154	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IEAAGIAC_00354	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IEAAGIAC_00355	3.73e-64	-	-	-	-	-	-	-	-
IEAAGIAC_00356	3.85e-98	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEAAGIAC_00357	5.25e-97	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IEAAGIAC_00358	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_00359	2.35e-107	-	-	-	-	-	-	-	-
IEAAGIAC_00360	1.08e-93	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEAAGIAC_00361	2.05e-181	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEAAGIAC_00362	3.42e-167	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
IEAAGIAC_00363	1.86e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IEAAGIAC_00364	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_00365	4.67e-174	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IEAAGIAC_00366	3.56e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
IEAAGIAC_00367	7.13e-56	-	-	-	-	-	-	-	-
IEAAGIAC_00368	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IEAAGIAC_00369	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEAAGIAC_00370	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_00371	1.99e-202	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IEAAGIAC_00372	8.03e-151	-	-	-	-	-	-	-	-
IEAAGIAC_00374	4.22e-149	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
IEAAGIAC_00375	2.87e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IEAAGIAC_00376	1.95e-118	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
IEAAGIAC_00377	3.58e-128	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IEAAGIAC_00378	2.38e-231	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IEAAGIAC_00379	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEAAGIAC_00380	3.05e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IEAAGIAC_00381	6.53e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEAAGIAC_00382	1.35e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IEAAGIAC_00383	1.22e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IEAAGIAC_00384	1.91e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IEAAGIAC_00385	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IEAAGIAC_00386	2.27e-222	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEAAGIAC_00387	1.38e-223	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IEAAGIAC_00388	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IEAAGIAC_00389	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IEAAGIAC_00390	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IEAAGIAC_00391	3.66e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IEAAGIAC_00392	8.82e-265	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IEAAGIAC_00393	4.24e-289	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IEAAGIAC_00394	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IEAAGIAC_00395	3.28e-196	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00396	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
IEAAGIAC_00397	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IEAAGIAC_00398	1.16e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IEAAGIAC_00399	4.17e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IEAAGIAC_00400	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IEAAGIAC_00401	8.5e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEAAGIAC_00402	2.83e-299	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IEAAGIAC_00403	1.37e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IEAAGIAC_00404	1.49e-158	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
IEAAGIAC_00405	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IEAAGIAC_00406	0.0	-	-	-	V	-	-	-	DNA restriction-modification system
IEAAGIAC_00408	6.86e-138	-	-	-	K	-	-	-	transcriptional regulator
IEAAGIAC_00409	2.54e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IEAAGIAC_00410	6.54e-140	-	-	-	K	-	-	-	Helix-turn-helix
IEAAGIAC_00411	4.58e-146	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IEAAGIAC_00412	5.45e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IEAAGIAC_00413	8.41e-83	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IEAAGIAC_00414	8.38e-182	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEAAGIAC_00415	1.23e-63	-	-	-	K	-	-	-	PFAM Helix-turn-helix
IEAAGIAC_00416	6.18e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IEAAGIAC_00417	7.67e-10	-	-	-	-	-	-	-	-
IEAAGIAC_00418	7.13e-37	-	-	-	P	ko:K10716	-	ko00000,ko02000	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IEAAGIAC_00419	2.36e-252	-	-	-	S	-	-	-	Membrane
IEAAGIAC_00420	9.79e-196	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IEAAGIAC_00421	7.02e-188	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IEAAGIAC_00422	2.63e-94	-	-	-	K	-	-	-	LytTr DNA-binding domain
IEAAGIAC_00423	3.27e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IEAAGIAC_00424	1.84e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IEAAGIAC_00425	2.47e-226	-	-	-	C	-	-	-	nadph quinone reductase
IEAAGIAC_00426	6.23e-102	ywnA	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00427	5.37e-107	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEAAGIAC_00428	6.72e-10	-	-	-	G	-	-	-	gluconokinase activity
IEAAGIAC_00429	1.78e-123	-	-	-	-	-	-	-	-
IEAAGIAC_00430	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IEAAGIAC_00431	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IEAAGIAC_00432	7.14e-259	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IEAAGIAC_00433	1.85e-53	-	-	-	-	-	-	-	-
IEAAGIAC_00434	1.46e-23	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IEAAGIAC_00435	1.57e-53	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IEAAGIAC_00436	4.04e-103	-	-	-	-	-	-	-	-
IEAAGIAC_00437	9.06e-182	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IEAAGIAC_00438	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IEAAGIAC_00439	4.98e-291	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IEAAGIAC_00440	1.89e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IEAAGIAC_00441	3.36e-180	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IEAAGIAC_00442	1.04e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00443	0.0	-	-	-	E	-	-	-	amino acid
IEAAGIAC_00444	8.98e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IEAAGIAC_00445	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IEAAGIAC_00446	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IEAAGIAC_00447	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IEAAGIAC_00448	5.18e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEAAGIAC_00449	2.59e-159	-	-	-	S	-	-	-	(CBS) domain
IEAAGIAC_00450	1.14e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IEAAGIAC_00451	1.81e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IEAAGIAC_00452	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEAAGIAC_00453	3.62e-46	yabO	-	-	J	-	-	-	S4 domain protein
IEAAGIAC_00454	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IEAAGIAC_00455	3.15e-78	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
IEAAGIAC_00456	2.07e-312	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IEAAGIAC_00457	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEAAGIAC_00458	0.0	-	-	-	S	-	-	-	membrane
IEAAGIAC_00459	0.0	-	-	-	S	-	-	-	membrane
IEAAGIAC_00460	3.19e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEAAGIAC_00461	9.21e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEAAGIAC_00462	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IEAAGIAC_00465	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IEAAGIAC_00466	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEAAGIAC_00467	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEAAGIAC_00468	8.54e-127	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
IEAAGIAC_00469	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEAAGIAC_00470	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IEAAGIAC_00471	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEAAGIAC_00472	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IEAAGIAC_00473	8.75e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEAAGIAC_00474	1.57e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IEAAGIAC_00475	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IEAAGIAC_00476	1.99e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IEAAGIAC_00477	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IEAAGIAC_00478	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IEAAGIAC_00479	3.69e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IEAAGIAC_00480	3e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IEAAGIAC_00481	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IEAAGIAC_00482	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IEAAGIAC_00483	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IEAAGIAC_00484	1.18e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IEAAGIAC_00485	6.1e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IEAAGIAC_00486	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEAAGIAC_00487	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IEAAGIAC_00488	3.04e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IEAAGIAC_00489	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IEAAGIAC_00490	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IEAAGIAC_00491	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IEAAGIAC_00492	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IEAAGIAC_00493	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IEAAGIAC_00494	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IEAAGIAC_00495	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IEAAGIAC_00496	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IEAAGIAC_00497	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IEAAGIAC_00498	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEAAGIAC_00499	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEAAGIAC_00500	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IEAAGIAC_00501	6.38e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEAAGIAC_00502	1.41e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEAAGIAC_00503	4.78e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEAAGIAC_00504	1.84e-191	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IEAAGIAC_00505	1.08e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEAAGIAC_00506	1.13e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IEAAGIAC_00507	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
IEAAGIAC_00508	3.79e-192	-	-	-	GM	-	-	-	NmrA-like family
IEAAGIAC_00509	8.56e-140	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IEAAGIAC_00510	1.83e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IEAAGIAC_00511	4.33e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IEAAGIAC_00512	8e-197	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IEAAGIAC_00513	2.02e-52	-	-	-	-	-	-	-	-
IEAAGIAC_00514	8.33e-17	-	-	-	-	-	-	-	-
IEAAGIAC_00515	7.96e-159	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEAAGIAC_00516	4.01e-235	-	-	-	S	-	-	-	AAA domain
IEAAGIAC_00522	8.3e-274	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IEAAGIAC_00523	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
IEAAGIAC_00524	3.99e-149	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IEAAGIAC_00525	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IEAAGIAC_00526	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IEAAGIAC_00527	3.27e-277	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IEAAGIAC_00528	4.14e-176	-	-	-	-	-	-	-	-
IEAAGIAC_00529	3.51e-189	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEAAGIAC_00530	9.66e-221	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IEAAGIAC_00531	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IEAAGIAC_00532	6.29e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IEAAGIAC_00533	1.27e-61	-	-	-	-	-	-	-	-
IEAAGIAC_00534	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
IEAAGIAC_00535	1.45e-92	-	-	-	K	-	-	-	Sigma-54 interaction domain
IEAAGIAC_00536	3.95e-72	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IEAAGIAC_00537	1.79e-106	ptsB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IEAAGIAC_00538	2.73e-177	ptsC	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IEAAGIAC_00539	2.69e-190	ptsD	-	-	G	ko:K02796,ko:K19509	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IEAAGIAC_00540	8.75e-146	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
IEAAGIAC_00541	1.31e-168	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
IEAAGIAC_00543	1.02e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IEAAGIAC_00544	2.13e-152	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
IEAAGIAC_00545	8e-137	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IEAAGIAC_00546	6.95e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IEAAGIAC_00547	2.06e-279	-	-	-	P	-	-	-	Voltage gated chloride channel
IEAAGIAC_00548	2.35e-244	-	-	-	S	-	-	-	Bacteriocin helveticin-J
IEAAGIAC_00549	6.54e-132	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IEAAGIAC_00550	7.19e-209	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IEAAGIAC_00551	6.52e-175	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
IEAAGIAC_00552	9.83e-185	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IEAAGIAC_00553	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IEAAGIAC_00554	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IEAAGIAC_00555	4.3e-100	-	-	-	K	-	-	-	acetyltransferase
IEAAGIAC_00556	1.93e-266	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IEAAGIAC_00557	3.69e-186	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IEAAGIAC_00558	4.67e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
IEAAGIAC_00559	4.13e-186	-	-	-	S	-	-	-	hydrolase
IEAAGIAC_00560	3.4e-55	-	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00561	5.08e-134	-	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00562	6.81e-308	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IEAAGIAC_00563	5.79e-170	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IEAAGIAC_00564	3.14e-94	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
IEAAGIAC_00565	3.34e-136	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
IEAAGIAC_00566	4.58e-168	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
IEAAGIAC_00567	5.66e-72	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IEAAGIAC_00568	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
IEAAGIAC_00569	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_00570	8.88e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IEAAGIAC_00571	1.15e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
IEAAGIAC_00572	0.0	-	-	-	E	-	-	-	Phospholipase B
IEAAGIAC_00573	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IEAAGIAC_00574	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
IEAAGIAC_00575	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IEAAGIAC_00576	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IEAAGIAC_00577	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
IEAAGIAC_00578	0.0	-	-	-	E	-	-	-	amino acid
IEAAGIAC_00579	1.95e-273	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IEAAGIAC_00580	1.97e-42	-	-	-	-	-	-	-	-
IEAAGIAC_00581	6.45e-91	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IEAAGIAC_00582	1.15e-63	-	-	-	-	-	-	-	-
IEAAGIAC_00583	8.49e-98	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IEAAGIAC_00584	7.52e-233	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEAAGIAC_00585	1.75e-164	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IEAAGIAC_00586	8.82e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
IEAAGIAC_00588	6.57e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00589	1.92e-163	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IEAAGIAC_00590	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
IEAAGIAC_00591	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IEAAGIAC_00592	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
IEAAGIAC_00593	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
IEAAGIAC_00594	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IEAAGIAC_00595	0.0	-	-	-	E	-	-	-	Peptidase family C69
IEAAGIAC_00596	3.41e-278	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IEAAGIAC_00597	3.3e-200	-	-	-	S	-	-	-	Alpha beta hydrolase
IEAAGIAC_00598	2.08e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IEAAGIAC_00599	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00600	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
IEAAGIAC_00601	1.89e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IEAAGIAC_00602	6.35e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00603	7.44e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IEAAGIAC_00604	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00605	3.24e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00606	1.68e-85	-	-	-	-	-	-	-	-
IEAAGIAC_00607	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IEAAGIAC_00608	4.09e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
IEAAGIAC_00609	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IEAAGIAC_00610	1.19e-109	-	-	-	S	-	-	-	Putative adhesin
IEAAGIAC_00612	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IEAAGIAC_00614	1.78e-286	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IEAAGIAC_00615	2.12e-182	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IEAAGIAC_00616	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IEAAGIAC_00617	4.67e-125	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
IEAAGIAC_00619	1.09e-61	-	-	-	S	-	-	-	Enterocin A Immunity
IEAAGIAC_00623	6.77e-71	-	-	-	S	-	-	-	Enterocin A Immunity
IEAAGIAC_00625	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IEAAGIAC_00626	2.42e-201	-	-	-	S	-	-	-	Phospholipase, patatin family
IEAAGIAC_00627	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00628	9.7e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00629	1.13e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IEAAGIAC_00630	9.53e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IEAAGIAC_00631	8.44e-217	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IEAAGIAC_00632	1.19e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IEAAGIAC_00633	4.68e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEAAGIAC_00634	1.98e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEAAGIAC_00635	8.28e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IEAAGIAC_00636	1.04e-77	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEAAGIAC_00637	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IEAAGIAC_00638	1.98e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IEAAGIAC_00639	9.52e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEAAGIAC_00640	3.15e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IEAAGIAC_00641	2.9e-67	-	-	-	-	-	-	-	-
IEAAGIAC_00642	1.96e-41	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
IEAAGIAC_00645	8.16e-236	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IEAAGIAC_00646	4.62e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IEAAGIAC_00647	1.39e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IEAAGIAC_00648	1.29e-70	-	-	-	S	-	-	-	Enterocin A Immunity
IEAAGIAC_00649	1.6e-175	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
IEAAGIAC_00650	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IEAAGIAC_00651	1.97e-150	-	-	-	C	-	-	-	nitroreductase
IEAAGIAC_00652	2.15e-167	-	-	-	-	-	-	-	-
IEAAGIAC_00653	4.03e-301	yhdP	-	-	S	-	-	-	Transporter associated domain
IEAAGIAC_00654	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IEAAGIAC_00655	6.91e-297	-	-	-	E	ko:K03294	-	ko00000	amino acid
IEAAGIAC_00656	1.34e-175	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IEAAGIAC_00657	2.59e-276	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IEAAGIAC_00658	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEAAGIAC_00661	7.39e-275	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IEAAGIAC_00662	3.74e-115	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
IEAAGIAC_00663	1.36e-100	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IEAAGIAC_00664	1.21e-206	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IEAAGIAC_00665	2.72e-208	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IEAAGIAC_00666	2.45e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IEAAGIAC_00667	8.69e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00668	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEAAGIAC_00669	2.16e-89	-	-	-	O	-	-	-	OsmC-like protein
IEAAGIAC_00670	1.16e-146	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IEAAGIAC_00671	2.04e-149	dltr	-	-	K	-	-	-	response regulator
IEAAGIAC_00672	2.9e-287	sptS	-	-	T	-	-	-	Histidine kinase
IEAAGIAC_00673	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IEAAGIAC_00674	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IEAAGIAC_00675	6.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IEAAGIAC_00677	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IEAAGIAC_00678	5.68e-91	-	-	-	-	-	-	-	-
IEAAGIAC_00679	8.04e-139	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IEAAGIAC_00680	1.98e-190	-	-	-	M	-	-	-	Glycosyl transferase family 2
IEAAGIAC_00681	7.6e-121	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IEAAGIAC_00682	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IEAAGIAC_00683	3.24e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IEAAGIAC_00684	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IEAAGIAC_00685	4.97e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IEAAGIAC_00686	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IEAAGIAC_00687	3.83e-204	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IEAAGIAC_00688	4.22e-38	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IEAAGIAC_00689	7.42e-108	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IEAAGIAC_00690	2.11e-277	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IEAAGIAC_00691	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IEAAGIAC_00692	9.95e-242	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IEAAGIAC_00693	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IEAAGIAC_00695	5.04e-17	-	-	-	K	-	-	-	transcriptional regulator
IEAAGIAC_00696	4.71e-62	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
IEAAGIAC_00698	5.53e-88	-	-	-	M	-	-	-	Sortase family
IEAAGIAC_00699	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IEAAGIAC_00700	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IEAAGIAC_00701	7.7e-186	-	-	-	M	ko:K02519	-	ko00000,ko03012,ko03029	domain protein
IEAAGIAC_00702	1.05e-217	-	-	-	I	-	-	-	Carboxylesterase family
IEAAGIAC_00703	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IEAAGIAC_00704	2.15e-158	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IEAAGIAC_00705	3.79e-68	-	-	-	-	-	-	-	-
IEAAGIAC_00706	6.8e-187	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IEAAGIAC_00707	1.17e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IEAAGIAC_00708	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IEAAGIAC_00709	2.18e-83	-	-	-	-	-	-	-	-
IEAAGIAC_00710	1.17e-17	-	-	-	-	-	-	-	-
IEAAGIAC_00711	6.28e-268	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IEAAGIAC_00712	5.66e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEAAGIAC_00713	1.75e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IEAAGIAC_00714	2.78e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IEAAGIAC_00715	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IEAAGIAC_00716	1.57e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IEAAGIAC_00717	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEAAGIAC_00718	7.32e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IEAAGIAC_00719	1e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEAAGIAC_00720	2.49e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEAAGIAC_00721	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEAAGIAC_00722	2.74e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEAAGIAC_00723	6.21e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IEAAGIAC_00724	5.29e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IEAAGIAC_00725	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IEAAGIAC_00726	1.81e-46	-	-	-	-	-	-	-	-
IEAAGIAC_00728	3.17e-247	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_00729	4.16e-240	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_00730	2.09e-116	ymdB	-	-	S	-	-	-	Macro domain protein
IEAAGIAC_00731	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IEAAGIAC_00732	5.89e-161	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IEAAGIAC_00733	3.03e-277	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IEAAGIAC_00734	3.03e-196	-	-	-	-	-	-	-	-
IEAAGIAC_00735	3.16e-93	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
IEAAGIAC_00736	7.26e-200	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
IEAAGIAC_00737	1.62e-195	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IEAAGIAC_00738	1.05e-176	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IEAAGIAC_00739	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
IEAAGIAC_00740	1.51e-123	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEAAGIAC_00741	1.63e-62	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IEAAGIAC_00742	1.24e-163	-	-	-	-	-	-	-	-
IEAAGIAC_00743	9.32e-67	-	-	-	-	-	-	-	-
IEAAGIAC_00744	8.69e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IEAAGIAC_00745	4.29e-174	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
IEAAGIAC_00746	5.95e-147	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IEAAGIAC_00747	4.06e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
IEAAGIAC_00748	1.91e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IEAAGIAC_00749	3.25e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IEAAGIAC_00750	1.61e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00751	2.56e-40	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IEAAGIAC_00752	8.57e-142	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IEAAGIAC_00753	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IEAAGIAC_00754	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_00755	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IEAAGIAC_00756	1.36e-50	-	-	-	-	-	-	-	-
IEAAGIAC_00757	1.4e-140	-	-	-	K	-	-	-	WHG domain
IEAAGIAC_00758	2.22e-125	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
IEAAGIAC_00759	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IEAAGIAC_00760	3.15e-256	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IEAAGIAC_00761	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IEAAGIAC_00762	3.82e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IEAAGIAC_00763	3.16e-125	cvpA	-	-	S	-	-	-	Colicin V production protein
IEAAGIAC_00764	1.75e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IEAAGIAC_00765	7.73e-199	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IEAAGIAC_00766	3.52e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IEAAGIAC_00767	3.67e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IEAAGIAC_00768	7.4e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IEAAGIAC_00769	1.89e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IEAAGIAC_00770	4.65e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IEAAGIAC_00771	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00772	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IEAAGIAC_00773	2.39e-156	vanR	-	-	K	-	-	-	response regulator
IEAAGIAC_00774	4.88e-262	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IEAAGIAC_00775	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEAAGIAC_00776	1.76e-182	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IEAAGIAC_00777	2.54e-211	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00778	5.5e-282	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IEAAGIAC_00779	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
IEAAGIAC_00780	5.63e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IEAAGIAC_00781	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IEAAGIAC_00782	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IEAAGIAC_00783	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IEAAGIAC_00784	2.58e-181	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IEAAGIAC_00785	1.78e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
IEAAGIAC_00786	6.35e-201	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IEAAGIAC_00787	1.06e-150	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IEAAGIAC_00788	5.98e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IEAAGIAC_00789	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IEAAGIAC_00790	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IEAAGIAC_00791	1.94e-267	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IEAAGIAC_00792	6.06e-54	-	-	-	-	-	-	-	-
IEAAGIAC_00793	2.71e-81	-	-	-	-	-	-	-	-
IEAAGIAC_00794	0.0	-	-	-	S	-	-	-	ABC transporter
IEAAGIAC_00795	8.94e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
IEAAGIAC_00796	2.22e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IEAAGIAC_00797	3.02e-53	-	-	-	-	-	-	-	-
IEAAGIAC_00798	7.58e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IEAAGIAC_00799	6.79e-105	-	-	-	-	-	-	-	-
IEAAGIAC_00800	3.06e-124	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEAAGIAC_00801	2.81e-49	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEAAGIAC_00802	6.41e-106	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IEAAGIAC_00803	1.57e-142	-	-	-	-	-	-	-	-
IEAAGIAC_00804	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
IEAAGIAC_00805	1.87e-58	-	-	-	-	-	-	-	-
IEAAGIAC_00806	4.8e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IEAAGIAC_00807	6.25e-181	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IEAAGIAC_00808	3.13e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IEAAGIAC_00809	1.18e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEAAGIAC_00810	0.0	-	-	-	E	-	-	-	Amino Acid
IEAAGIAC_00811	7.68e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00812	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IEAAGIAC_00813	2.95e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
IEAAGIAC_00814	9.27e-36	-	-	-	-	-	-	-	-
IEAAGIAC_00815	1.93e-68	-	-	-	-	-	-	-	-
IEAAGIAC_00816	8.32e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IEAAGIAC_00817	1.96e-13	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IEAAGIAC_00818	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IEAAGIAC_00819	8.06e-165	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IEAAGIAC_00820	3.25e-185	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IEAAGIAC_00821	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
IEAAGIAC_00823	5.92e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IEAAGIAC_00824	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IEAAGIAC_00825	1.19e-157	-	-	-	S	-	-	-	Peptidase_C39 like family
IEAAGIAC_00826	5.82e-136	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IEAAGIAC_00827	7.58e-210	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IEAAGIAC_00828	1.13e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEAAGIAC_00829	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
IEAAGIAC_00830	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
IEAAGIAC_00831	2.5e-189	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IEAAGIAC_00832	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IEAAGIAC_00833	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_00834	1.74e-198	-	-	-	EG	-	-	-	EamA-like transporter family
IEAAGIAC_00835	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IEAAGIAC_00836	5.13e-215	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IEAAGIAC_00837	1.31e-178	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IEAAGIAC_00838	9e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IEAAGIAC_00839	1.27e-81	-	-	-	-	-	-	-	-
IEAAGIAC_00840	8.03e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IEAAGIAC_00841	9.08e-259	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IEAAGIAC_00842	5.96e-302	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEAAGIAC_00843	8.09e-181	-	-	-	S	-	-	-	PAS domain
IEAAGIAC_00844	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
IEAAGIAC_00845	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IEAAGIAC_00846	5.86e-186	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IEAAGIAC_00847	1.15e-109	-	-	-	-	-	-	-	-
IEAAGIAC_00848	2.19e-111	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IEAAGIAC_00849	2.42e-69	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IEAAGIAC_00850	0.0	-	-	-	GM	ko:K13732	ko05100,map05100	ko00000,ko00001	domain, Protein
IEAAGIAC_00851	1.63e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IEAAGIAC_00852	2.3e-118	-	-	-	S	-	-	-	PAS domain
IEAAGIAC_00853	2.02e-308	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IEAAGIAC_00854	4.73e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IEAAGIAC_00855	1.69e-143	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IEAAGIAC_00856	1.24e-191	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEAAGIAC_00857	3.3e-234	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
IEAAGIAC_00858	2.77e-251	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IEAAGIAC_00859	4.36e-200	dkgB	-	-	S	-	-	-	reductase
IEAAGIAC_00860	2.07e-202	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IEAAGIAC_00861	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IEAAGIAC_00862	8.41e-260	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IEAAGIAC_00863	3.57e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
IEAAGIAC_00864	2.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IEAAGIAC_00865	7.72e-313	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
IEAAGIAC_00866	9.33e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IEAAGIAC_00867	4.76e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IEAAGIAC_00868	2.62e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
IEAAGIAC_00869	9.05e-114	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IEAAGIAC_00870	8.58e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IEAAGIAC_00871	1.86e-213	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
IEAAGIAC_00872	1.55e-204	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IEAAGIAC_00873	4.41e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IEAAGIAC_00874	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IEAAGIAC_00875	3.51e-182	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IEAAGIAC_00876	1.29e-164	-	-	-	S	-	-	-	SNARE associated Golgi protein
IEAAGIAC_00877	2.89e-227	-	-	-	-	-	-	-	-
IEAAGIAC_00878	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IEAAGIAC_00879	3.44e-200	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IEAAGIAC_00880	3.32e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IEAAGIAC_00881	2.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
IEAAGIAC_00882	6.85e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IEAAGIAC_00883	6.46e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEAAGIAC_00884	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
IEAAGIAC_00885	5.3e-81	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEAAGIAC_00886	1.91e-98	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEAAGIAC_00887	1.82e-310	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IEAAGIAC_00888	2.79e-59	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IEAAGIAC_00889	2.87e-101	-	-	-	L	-	-	-	NUDIX domain
IEAAGIAC_00890	2.21e-33	-	-	-	S	-	-	-	M26 IgA1-specific Metallo-endopeptidase C-terminal region
IEAAGIAC_00891	0.0	-	-	-	S	-	-	-	M26 IgA1-specific Metallo-endopeptidase C-terminal region
IEAAGIAC_00893	2.91e-193	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IEAAGIAC_00894	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IEAAGIAC_00895	3.04e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IEAAGIAC_00896	2.21e-276	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
IEAAGIAC_00897	0.0	yhaN	-	-	L	-	-	-	AAA domain
IEAAGIAC_00898	1.25e-236	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IEAAGIAC_00899	2.5e-202	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IEAAGIAC_00900	2.82e-46	-	-	-	S	-	-	-	YtxH-like protein
IEAAGIAC_00901	2.56e-85	-	-	-	-	-	-	-	-
IEAAGIAC_00902	2.38e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IEAAGIAC_00903	1.97e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_00904	1.65e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IEAAGIAC_00905	1.2e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IEAAGIAC_00906	1.1e-80	-	-	-	-	-	-	-	-
IEAAGIAC_00907	1.11e-70	ytpP	-	-	CO	-	-	-	Thioredoxin
IEAAGIAC_00908	2.07e-155	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEAAGIAC_00909	7.98e-111	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
IEAAGIAC_00910	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IEAAGIAC_00911	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEAAGIAC_00912	1.36e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IEAAGIAC_00913	2.33e-130	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEAAGIAC_00914	1.2e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IEAAGIAC_00915	1.26e-302	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
IEAAGIAC_00916	1.05e-199	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IEAAGIAC_00917	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEAAGIAC_00918	5.61e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
IEAAGIAC_00919	1.43e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IEAAGIAC_00920	2.07e-300	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IEAAGIAC_00921	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEAAGIAC_00922	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IEAAGIAC_00923	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEAAGIAC_00924	1.38e-212	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IEAAGIAC_00925	5.71e-116	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IEAAGIAC_00926	1.12e-268	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IEAAGIAC_00927	2.25e-151	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IEAAGIAC_00928	8.88e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IEAAGIAC_00929	4.36e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IEAAGIAC_00930	4.45e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IEAAGIAC_00931	2.89e-118	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IEAAGIAC_00932	1.89e-169	csrR	-	-	K	-	-	-	response regulator
IEAAGIAC_00933	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IEAAGIAC_00934	6.41e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEAAGIAC_00935	9.98e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IEAAGIAC_00936	1.49e-176	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEAAGIAC_00937	1.19e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IEAAGIAC_00938	3.68e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEAAGIAC_00939	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEAAGIAC_00940	6.41e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEAAGIAC_00941	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEAAGIAC_00942	0.0	-	-	-	S	-	-	-	membrane
IEAAGIAC_00943	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IEAAGIAC_00944	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IEAAGIAC_00945	2.56e-123	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEAAGIAC_00946	2.67e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IEAAGIAC_00947	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IEAAGIAC_00948	2.09e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IEAAGIAC_00949	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IEAAGIAC_00950	8.88e-216	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IEAAGIAC_00951	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IEAAGIAC_00952	6.96e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IEAAGIAC_00953	1.63e-193	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IEAAGIAC_00955	3.02e-227	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IEAAGIAC_00956	1.76e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IEAAGIAC_00957	3.44e-282	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IEAAGIAC_00958	1.98e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IEAAGIAC_00959	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEAAGIAC_00960	3.14e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IEAAGIAC_00961	1.37e-146	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IEAAGIAC_00962	1.37e-115	-	-	-	-	-	-	-	-
IEAAGIAC_00963	4.87e-101	-	-	-	-	-	-	-	-
IEAAGIAC_00964	5.48e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IEAAGIAC_00965	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IEAAGIAC_00966	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IEAAGIAC_00967	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IEAAGIAC_00968	1.02e-34	-	-	-	-	-	-	-	-
IEAAGIAC_00969	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IEAAGIAC_00970	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEAAGIAC_00971	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IEAAGIAC_00972	2.32e-153	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IEAAGIAC_00973	2.77e-203	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IEAAGIAC_00974	3.12e-139	yjbH	-	-	Q	-	-	-	Thioredoxin
IEAAGIAC_00975	1.7e-141	-	-	-	S	-	-	-	CYTH
IEAAGIAC_00976	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IEAAGIAC_00977	3.58e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEAAGIAC_00978	5.37e-218	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IEAAGIAC_00979	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IEAAGIAC_00980	1.03e-30	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IEAAGIAC_00981	1.03e-215	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IEAAGIAC_00982	3.38e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IEAAGIAC_00983	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IEAAGIAC_00984	5.14e-268	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IEAAGIAC_00985	8e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IEAAGIAC_00986	6.82e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
IEAAGIAC_00987	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IEAAGIAC_00988	2.47e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IEAAGIAC_00989	4.65e-296	ymfH	-	-	S	-	-	-	Peptidase M16
IEAAGIAC_00990	4.27e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IEAAGIAC_00991	2.43e-177	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IEAAGIAC_00992	3.1e-125	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEAAGIAC_00993	2.99e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IEAAGIAC_00994	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IEAAGIAC_00995	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IEAAGIAC_00996	2.31e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IEAAGIAC_00997	1.03e-284	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IEAAGIAC_00998	7.79e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IEAAGIAC_00999	3.97e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEAAGIAC_01000	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IEAAGIAC_01001	3.42e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IEAAGIAC_01002	6.45e-41	-	-	-	-	-	-	-	-
IEAAGIAC_01003	1.67e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IEAAGIAC_01004	5.09e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IEAAGIAC_01005	1.57e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IEAAGIAC_01006	3.65e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IEAAGIAC_01007	4.59e-197	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IEAAGIAC_01008	5.34e-256	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEAAGIAC_01009	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IEAAGIAC_01010	4.76e-206	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IEAAGIAC_01011	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IEAAGIAC_01012	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IEAAGIAC_01013	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IEAAGIAC_01014	2.04e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IEAAGIAC_01015	4.53e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IEAAGIAC_01016	6.27e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IEAAGIAC_01017	2.02e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IEAAGIAC_01018	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEAAGIAC_01019	0.0	ycaM	-	-	E	-	-	-	amino acid
IEAAGIAC_01021	3.72e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IEAAGIAC_01022	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEAAGIAC_01023	2.01e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IEAAGIAC_01024	5.9e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IEAAGIAC_01025	1.68e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEAAGIAC_01026	7.52e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IEAAGIAC_01027	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IEAAGIAC_01028	4.19e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IEAAGIAC_01029	8.94e-135	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IEAAGIAC_01030	7.71e-111	-	-	-	-	-	-	-	-
IEAAGIAC_01031	5.96e-122	-	-	-	-	-	-	-	-
IEAAGIAC_01032	4.84e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IEAAGIAC_01033	8.42e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IEAAGIAC_01034	2.59e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IEAAGIAC_01035	1.75e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IEAAGIAC_01036	9.09e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IEAAGIAC_01037	5.31e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IEAAGIAC_01038	2.82e-259	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IEAAGIAC_01039	5.91e-171	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_01040	2.65e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_01041	1.71e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IEAAGIAC_01042	1.5e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEAAGIAC_01043	3.49e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
IEAAGIAC_01044	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEAAGIAC_01045	1.39e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IEAAGIAC_01046	3.53e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEAAGIAC_01047	2.48e-80	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEAAGIAC_01048	1.11e-252	-	-	-	S	-	-	-	Putative adhesin
IEAAGIAC_01049	6.94e-148	-	-	-	-	-	-	-	-
IEAAGIAC_01050	1.4e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IEAAGIAC_01051	8.84e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IEAAGIAC_01052	1.37e-272	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEAAGIAC_01053	2.53e-123	-	-	-	S	-	-	-	VanZ like family
IEAAGIAC_01054	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IEAAGIAC_01055	1.82e-229	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IEAAGIAC_01056	3.47e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IEAAGIAC_01057	9.23e-55	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
IEAAGIAC_01058	3.97e-77	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
IEAAGIAC_01060	4.33e-109	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IEAAGIAC_01061	5.71e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IEAAGIAC_01062	3.36e-289	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEAAGIAC_01064	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IEAAGIAC_01065	9.01e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IEAAGIAC_01066	4.09e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IEAAGIAC_01067	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEAAGIAC_01068	1.91e-85	-	-	-	-	-	-	-	-
IEAAGIAC_01069	1.17e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IEAAGIAC_01070	3.6e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEAAGIAC_01071	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IEAAGIAC_01072	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IEAAGIAC_01073	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IEAAGIAC_01074	1.9e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
IEAAGIAC_01075	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IEAAGIAC_01076	1.47e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IEAAGIAC_01077	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IEAAGIAC_01078	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IEAAGIAC_01079	1.74e-117	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_01080	3.42e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEAAGIAC_01081	1.34e-199	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IEAAGIAC_01082	6.82e-94	-	-	-	L	-	-	-	nuclease
IEAAGIAC_01083	4.02e-180	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IEAAGIAC_01084	2e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
IEAAGIAC_01085	1.86e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEAAGIAC_01086	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IEAAGIAC_01087	6.36e-37	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IEAAGIAC_01088	2.48e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEAAGIAC_01089	8.86e-133	-	-	-	I	-	-	-	PAP2 superfamily
IEAAGIAC_01090	6.16e-134	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IEAAGIAC_01092	1.43e-43	-	-	-	-	-	-	-	-
IEAAGIAC_01093	5.49e-76	-	-	-	-	-	-	-	-
IEAAGIAC_01094	2.65e-44	-	-	-	-	-	-	-	-
IEAAGIAC_01096	3.84e-258	-	-	-	LM	-	-	-	gp58-like protein
IEAAGIAC_01097	2.03e-67	-	-	-	S	-	-	-	Phage tail protein
IEAAGIAC_01098	4.47e-163	-	-	-	D	-	-	-	Phage tail tape measure protein
IEAAGIAC_01099	9.04e-18	-	-	-	-	-	-	-	-
IEAAGIAC_01100	2.28e-28	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
IEAAGIAC_01101	1.16e-94	-	-	-	S	-	-	-	Phage major tail protein 2
IEAAGIAC_01103	1.89e-30	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IEAAGIAC_01104	9.27e-35	-	-	-	-	-	-	-	-
IEAAGIAC_01105	8.38e-40	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IEAAGIAC_01106	3.81e-107	-	-	-	-	-	-	-	-
IEAAGIAC_01107	1.3e-30	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
IEAAGIAC_01108	3.32e-34	-	-	-	-	-	-	-	-
IEAAGIAC_01109	5.82e-145	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
IEAAGIAC_01110	1.22e-132	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IEAAGIAC_01111	5.97e-269	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
IEAAGIAC_01113	8.06e-75	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
IEAAGIAC_01115	1.02e-65	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
IEAAGIAC_01117	6.35e-67	-	-	-	S	-	-	-	VRR_NUC
IEAAGIAC_01122	4.22e-238	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
IEAAGIAC_01123	2.61e-128	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
IEAAGIAC_01125	1.52e-49	-	-	-	-	-	-	-	-
IEAAGIAC_01126	2.96e-138	-	-	-	L	-	-	-	AAA domain
IEAAGIAC_01128	2.8e-09	-	-	-	K	-	-	-	Transcriptional
IEAAGIAC_01129	4.51e-268	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IEAAGIAC_01130	2.34e-07	-	-	-	S	-	-	-	helicase activity
IEAAGIAC_01132	1.21e-55	-	-	-	S	-	-	-	Siphovirus Gp157
IEAAGIAC_01134	6.62e-22	-	-	-	-	-	-	-	-
IEAAGIAC_01135	2.58e-41	-	-	-	-	-	-	-	-
IEAAGIAC_01137	2.8e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IEAAGIAC_01138	4.58e-88	-	-	-	E	-	-	-	Zn peptidase
IEAAGIAC_01139	5.4e-39	-	-	-	S	-	-	-	Bacterial PH domain
IEAAGIAC_01140	6.92e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IEAAGIAC_01142	1.63e-199	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IEAAGIAC_01143	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IEAAGIAC_01144	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IEAAGIAC_01145	9.23e-124	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEAAGIAC_01146	5.29e-239	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEAAGIAC_01147	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEAAGIAC_01148	0.0	potE	-	-	E	-	-	-	Amino Acid
IEAAGIAC_01149	5.93e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEAAGIAC_01150	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IEAAGIAC_01151	5.42e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IEAAGIAC_01152	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEAAGIAC_01153	1.73e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IEAAGIAC_01154	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IEAAGIAC_01155	2.77e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IEAAGIAC_01156	3.77e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IEAAGIAC_01157	1.98e-120	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
IEAAGIAC_01158	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IEAAGIAC_01159	3.94e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IEAAGIAC_01160	1.42e-212	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEAAGIAC_01161	4.75e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEAAGIAC_01162	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IEAAGIAC_01163	4.44e-62	-	-	-	J	-	-	-	ribosomal protein
IEAAGIAC_01164	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IEAAGIAC_01165	2.72e-281	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IEAAGIAC_01166	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IEAAGIAC_01167	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEAAGIAC_01168	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IEAAGIAC_01169	2.69e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IEAAGIAC_01170	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IEAAGIAC_01171	5.91e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEAAGIAC_01172	2.02e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IEAAGIAC_01173	1.01e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IEAAGIAC_01174	7.17e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IEAAGIAC_01175	7.4e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IEAAGIAC_01176	3.11e-249	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IEAAGIAC_01177	1.16e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IEAAGIAC_01178	5.39e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IEAAGIAC_01179	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IEAAGIAC_01180	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IEAAGIAC_01181	9.8e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IEAAGIAC_01182	6.95e-45	ynzC	-	-	S	-	-	-	UPF0291 protein
IEAAGIAC_01183	7.82e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEAAGIAC_01184	6.17e-151	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
IEAAGIAC_01185	4.67e-90	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
IEAAGIAC_01186	3.73e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IEAAGIAC_01187	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IEAAGIAC_01188	3.7e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IEAAGIAC_01189	1.2e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEAAGIAC_01190	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IEAAGIAC_01191	1.99e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEAAGIAC_01192	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IEAAGIAC_01193	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IEAAGIAC_01194	6.74e-258	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IEAAGIAC_01195	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IEAAGIAC_01196	1.29e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IEAAGIAC_01197	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IEAAGIAC_01198	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IEAAGIAC_01199	1.06e-206	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IEAAGIAC_01200	3.25e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_01201	8.34e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IEAAGIAC_01202	9.96e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IEAAGIAC_01203	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEAAGIAC_01204	4.31e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IEAAGIAC_01205	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEAAGIAC_01206	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IEAAGIAC_01207	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IEAAGIAC_01208	6.36e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IEAAGIAC_01209	9.07e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IEAAGIAC_01210	7.8e-156	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IEAAGIAC_01211	6.45e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IEAAGIAC_01212	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IEAAGIAC_01213	5.24e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IEAAGIAC_01214	8.6e-308	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IEAAGIAC_01215	1.96e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IEAAGIAC_01216	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEAAGIAC_01217	3.3e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IEAAGIAC_01218	3.6e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IEAAGIAC_01219	7.04e-63	-	-	-	-	-	-	-	-
IEAAGIAC_01220	0.0	-	-	-	M	-	-	-	domain protein
IEAAGIAC_01221	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IEAAGIAC_01222	0.0	-	-	-	S	-	-	-	domain, Protein
IEAAGIAC_01223	1.59e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEAAGIAC_01224	6.49e-129	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IEAAGIAC_01225	1.87e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEAAGIAC_01226	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
IEAAGIAC_01227	6.47e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
IEAAGIAC_01228	1.45e-35	-	-	-	-	-	-	-	-
IEAAGIAC_01229	1.09e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IEAAGIAC_01230	9.8e-197	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
IEAAGIAC_01233	5.21e-06	-	-	-	HJ	-	-	-	PFAM RimK-like ATP-grasp domain
IEAAGIAC_01234	1.01e-81	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_01236	2.68e-06	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IEAAGIAC_01237	6.82e-53	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IEAAGIAC_01238	7.54e-24	-	-	-	-	-	-	-	-
IEAAGIAC_01240	2.57e-40	-	-	-	-	-	-	-	-
IEAAGIAC_01242	6.48e-176	-	-	-	S	-	-	-	Alpha beta hydrolase
IEAAGIAC_01243	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IEAAGIAC_01244	4.38e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IEAAGIAC_01245	1.83e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
IEAAGIAC_01246	1.5e-20	-	-	-	S	-	-	-	CsbD-like
IEAAGIAC_01247	8.97e-264	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
IEAAGIAC_01248	7.46e-199	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
IEAAGIAC_01249	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IEAAGIAC_01250	1.44e-309	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IEAAGIAC_01251	0.0	fusA1	-	-	J	-	-	-	elongation factor G
IEAAGIAC_01252	2.21e-186	-	-	-	K	-	-	-	Helix-turn-helix domain
IEAAGIAC_01253	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IEAAGIAC_01254	1.07e-23	-	-	-	-	-	-	-	-
IEAAGIAC_01255	5.91e-196	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
IEAAGIAC_01256	1.07e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IEAAGIAC_01257	2.92e-162	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IEAAGIAC_01258	3.07e-76	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IEAAGIAC_01259	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
IEAAGIAC_01260	1.84e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IEAAGIAC_01261	8.71e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IEAAGIAC_01262	2.95e-204	-	-	-	I	-	-	-	Acyltransferase
IEAAGIAC_01263	6.89e-279	-	-	-	S	-	-	-	Sterol carrier protein domain
IEAAGIAC_01265	4.33e-314	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IEAAGIAC_01267	0.0	-	-	-	-	-	-	-	-
IEAAGIAC_01268	4.65e-278	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IEAAGIAC_01269	6.29e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IEAAGIAC_01270	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IEAAGIAC_01271	1.15e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IEAAGIAC_01272	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IEAAGIAC_01273	1.42e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IEAAGIAC_01274	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IEAAGIAC_01275	3.41e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IEAAGIAC_01276	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IEAAGIAC_01277	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEAAGIAC_01278	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEAAGIAC_01279	9.19e-266	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IEAAGIAC_01280	5.33e-30	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IEAAGIAC_01281	3.59e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IEAAGIAC_01282	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IEAAGIAC_01283	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IEAAGIAC_01284	8.89e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IEAAGIAC_01285	4.86e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEAAGIAC_01286	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IEAAGIAC_01287	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IEAAGIAC_01288	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IEAAGIAC_01289	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEAAGIAC_01290	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IEAAGIAC_01291	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEAAGIAC_01293	1.09e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IEAAGIAC_01294	3.07e-295	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
IEAAGIAC_01295	1.46e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IEAAGIAC_01296	8e-314	ynbB	-	-	P	-	-	-	aluminum resistance
IEAAGIAC_01297	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IEAAGIAC_01298	0.0	-	-	-	E	-	-	-	Amino acid permease
IEAAGIAC_01299	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IEAAGIAC_01300	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
IEAAGIAC_01301	1.25e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
IEAAGIAC_01302	9.69e-99	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
IEAAGIAC_01303	3.21e-117	-	-	-	-	-	-	-	-
IEAAGIAC_01304	4.62e-99	-	-	-	-	-	-	-	-
IEAAGIAC_01305	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IEAAGIAC_01306	4.93e-98	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
IEAAGIAC_01307	1.38e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IEAAGIAC_01308	3.28e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IEAAGIAC_01309	1.45e-145	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IEAAGIAC_01310	1.89e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IEAAGIAC_01311	5.48e-300	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IEAAGIAC_01312	3.29e-161	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IEAAGIAC_01313	8.43e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IEAAGIAC_01314	9.42e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEAAGIAC_01315	1.78e-206	-	-	-	S	-	-	-	Aldo/keto reductase family
IEAAGIAC_01316	2.55e-167	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IEAAGIAC_01317	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IEAAGIAC_01318	1.02e-201	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IEAAGIAC_01319	7.49e-240	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
IEAAGIAC_01320	2.39e-189	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IEAAGIAC_01321	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
IEAAGIAC_01322	2.36e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IEAAGIAC_01323	1.99e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IEAAGIAC_01324	5.12e-243	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IEAAGIAC_01325	4.63e-88	-	-	-	S	-	-	-	SdpI/YhfL protein family
IEAAGIAC_01326	5.43e-166	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IEAAGIAC_01327	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IEAAGIAC_01328	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IEAAGIAC_01329	3.73e-137	vanZ	-	-	V	-	-	-	VanZ like family
IEAAGIAC_01330	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IEAAGIAC_01331	1.32e-299	-	-	-	EGP	-	-	-	Major Facilitator
IEAAGIAC_01332	3.21e-89	-	-	-	-	-	-	-	-
IEAAGIAC_01335	7.92e-247	ampC	-	-	V	-	-	-	Beta-lactamase
IEAAGIAC_01336	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
IEAAGIAC_01337	4.75e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IEAAGIAC_01338	1.8e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEAAGIAC_01339	2.16e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IEAAGIAC_01340	8.5e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IEAAGIAC_01341	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IEAAGIAC_01342	7.4e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IEAAGIAC_01343	1.75e-35	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEAAGIAC_01344	5.6e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IEAAGIAC_01345	1.13e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEAAGIAC_01346	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEAAGIAC_01347	1.21e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IEAAGIAC_01348	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEAAGIAC_01349	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IEAAGIAC_01350	3.07e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IEAAGIAC_01351	3.53e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IEAAGIAC_01352	3.34e-18	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
IEAAGIAC_01353	5.54e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IEAAGIAC_01354	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IEAAGIAC_01355	3.74e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IEAAGIAC_01356	3.52e-106	uspA	-	-	T	-	-	-	universal stress protein
IEAAGIAC_01357	9.34e-08	-	-	-	-	-	-	-	-
IEAAGIAC_01358	2.36e-306	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IEAAGIAC_01359	1.06e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IEAAGIAC_01360	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IEAAGIAC_01362	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IEAAGIAC_01363	6.1e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IEAAGIAC_01364	4.43e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEAAGIAC_01365	3.13e-159	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IEAAGIAC_01366	4.04e-232	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
IEAAGIAC_01367	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IEAAGIAC_01368	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IEAAGIAC_01369	1.57e-299	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IEAAGIAC_01370	6.37e-160	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IEAAGIAC_01371	9.17e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IEAAGIAC_01372	3.11e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IEAAGIAC_01373	4.78e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IEAAGIAC_01374	2.31e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
IEAAGIAC_01375	2.36e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IEAAGIAC_01376	2.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IEAAGIAC_01377	1.89e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IEAAGIAC_01378	1.17e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IEAAGIAC_01379	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IEAAGIAC_01380	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IEAAGIAC_01381	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEAAGIAC_01382	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEAAGIAC_01383	9.56e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEAAGIAC_01384	5.24e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IEAAGIAC_01385	5.2e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IEAAGIAC_01386	6.35e-311	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEAAGIAC_01387	9.26e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IEAAGIAC_01388	1.36e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IEAAGIAC_01389	3.82e-185	ylmH	-	-	S	-	-	-	S4 domain protein
IEAAGIAC_01390	8.99e-162	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IEAAGIAC_01391	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEAAGIAC_01392	1.37e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IEAAGIAC_01393	1.81e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IEAAGIAC_01394	6.32e-52	-	-	-	-	-	-	-	-
IEAAGIAC_01395	1.02e-164	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEAAGIAC_01396	8.66e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IEAAGIAC_01397	1.27e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IEAAGIAC_01398	6.09e-276	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IEAAGIAC_01399	2.24e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
IEAAGIAC_01400	1.7e-149	-	-	-	S	-	-	-	repeat protein
IEAAGIAC_01401	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IEAAGIAC_01402	5.18e-222	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IEAAGIAC_01403	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEAAGIAC_01404	3.08e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IEAAGIAC_01405	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEAAGIAC_01406	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IEAAGIAC_01407	5.55e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IEAAGIAC_01408	4e-66	ylbG	-	-	S	-	-	-	UPF0298 protein
IEAAGIAC_01409	1.23e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IEAAGIAC_01410	5.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEAAGIAC_01411	9.82e-235	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IEAAGIAC_01412	4.3e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IEAAGIAC_01413	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IEAAGIAC_01414	6.83e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IEAAGIAC_01415	1.27e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IEAAGIAC_01416	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IEAAGIAC_01417	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEAAGIAC_01418	3.88e-204	-	-	-	-	-	-	-	-
IEAAGIAC_01419	2.45e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEAAGIAC_01420	2.09e-277	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IEAAGIAC_01421	4.32e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IEAAGIAC_01422	1.26e-132	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IEAAGIAC_01423	6.6e-115	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEAAGIAC_01424	1.1e-108	-	-	-	-	-	-	-	-
IEAAGIAC_01426	2.41e-150	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
IEAAGIAC_01427	1.02e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IEAAGIAC_01428	8.1e-282	-	-	-	-	-	-	-	-
IEAAGIAC_01429	4.67e-155	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
IEAAGIAC_01430	2.09e-207	-	-	-	-	-	-	-	-
IEAAGIAC_01431	5.8e-101	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IEAAGIAC_01432	2.63e-206	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IEAAGIAC_01433	2.95e-184	epsB	-	-	M	-	-	-	biosynthesis protein
IEAAGIAC_01434	2.21e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IEAAGIAC_01435	3.03e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IEAAGIAC_01436	7.75e-153	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
IEAAGIAC_01437	4.75e-60	-	-	-	-	-	-	-	-
IEAAGIAC_01438	6.37e-259	wchF	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
IEAAGIAC_01439	8.22e-138	-	-	-	M	-	-	-	Glycosyl transferases group 1
IEAAGIAC_01440	3.94e-09	-	2.4.1.305	GT2	M	ko:K16698,ko:K21363	-	ko00000,ko01000,ko01003,ko01005	COG0463 Glycosyltransferases involved in cell wall biogenesis
IEAAGIAC_01441	1.25e-94	-	-	-	M	-	-	-	Glycosyl transferases group 1
IEAAGIAC_01442	2.02e-124	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IEAAGIAC_01443	3.74e-266	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IEAAGIAC_01444	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IEAAGIAC_01445	3.25e-44	-	-	-	-	-	-	-	-
IEAAGIAC_01446	1.12e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IEAAGIAC_01447	3.9e-30	-	-	-	-	-	-	-	-
IEAAGIAC_01448	1.39e-186	-	-	-	-	-	-	-	-
IEAAGIAC_01449	1.34e-63	-	-	-	S	-	-	-	Protein conserved in bacteria
IEAAGIAC_01450	4.11e-110	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IEAAGIAC_01451	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEAAGIAC_01452	5.45e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IEAAGIAC_01453	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEAAGIAC_01454	3.03e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IEAAGIAC_01455	1.02e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEAAGIAC_01456	1.24e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IEAAGIAC_01457	1.9e-195	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IEAAGIAC_01458	3.33e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IEAAGIAC_01459	1.98e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEAAGIAC_01460	3.85e-179	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IEAAGIAC_01461	2.13e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IEAAGIAC_01462	2.78e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IEAAGIAC_01463	9.51e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IEAAGIAC_01464	4.98e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEAAGIAC_01465	3.42e-271	-	-	-	D	-	-	-	nuclear chromosome segregation
IEAAGIAC_01466	1.01e-194	-	-	-	-	-	-	-	-
IEAAGIAC_01467	5.73e-149	-	-	-	-	-	-	-	-
IEAAGIAC_01468	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IEAAGIAC_01469	1.41e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEAAGIAC_01470	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEAAGIAC_01471	1.81e-310	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEAAGIAC_01472	1.69e-177	-	-	-	L	-	-	-	oxidized base lesion DNA N-glycosylase activity
IEAAGIAC_01473	7.24e-97	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IEAAGIAC_01474	5.5e-42	-	-	-	-	-	-	-	-
IEAAGIAC_01475	1.11e-52	-	-	-	-	-	-	-	-
IEAAGIAC_01476	1.07e-257	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IEAAGIAC_01477	5.21e-178	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IEAAGIAC_01478	5.03e-179	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IEAAGIAC_01479	9.06e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IEAAGIAC_01480	1.57e-107	-	-	-	-	-	-	-	-
IEAAGIAC_01481	1.38e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IEAAGIAC_01482	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IEAAGIAC_01483	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IEAAGIAC_01484	7.96e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IEAAGIAC_01485	2.2e-08	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS sugar transporter
IEAAGIAC_01486	9.54e-155	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
IEAAGIAC_01487	1.24e-12	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
IEAAGIAC_01488	9.15e-34	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
IEAAGIAC_01489	1.82e-28	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	system, Lactose Cellobiose specific IIB subunit
IEAAGIAC_01490	7.13e-164	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEAAGIAC_01491	6.85e-302	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IEAAGIAC_01492	1.15e-103	-	-	-	K	-	-	-	LytTr DNA-binding domain
IEAAGIAC_01493	2.75e-167	-	-	-	S	-	-	-	membrane
IEAAGIAC_01495	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IEAAGIAC_01496	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IEAAGIAC_01497	9.17e-142	-	-	-	-	-	-	-	-
IEAAGIAC_01498	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
IEAAGIAC_01499	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IEAAGIAC_01500	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEAAGIAC_01501	3.1e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IEAAGIAC_01502	5.68e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IEAAGIAC_01503	2.39e-75	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IEAAGIAC_01504	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEAAGIAC_01505	4.04e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEAAGIAC_01506	3.56e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IEAAGIAC_01507	1.61e-294	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IEAAGIAC_01508	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IEAAGIAC_01509	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IEAAGIAC_01510	9.7e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEAAGIAC_01511	1.42e-54	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IEAAGIAC_01512	1.61e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
IEAAGIAC_01513	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEAAGIAC_01514	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IEAAGIAC_01515	3.65e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IEAAGIAC_01524	8.28e-19	-	-	-	-	-	-	-	-
IEAAGIAC_01525	9.97e-19	-	-	-	K	-	-	-	transcriptional
IEAAGIAC_01526	4.22e-73	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IEAAGIAC_01527	1.01e-185	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IEAAGIAC_01528	3.6e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEAAGIAC_01529	2.23e-155	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IEAAGIAC_01530	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IEAAGIAC_01531	6.59e-275	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEAAGIAC_01532	1.21e-177	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IEAAGIAC_01533	2.92e-37	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEAAGIAC_01534	1.33e-64	-	-	-	-	-	-	-	-
IEAAGIAC_01535	8.53e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IEAAGIAC_01536	4.41e-224	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IEAAGIAC_01537	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
IEAAGIAC_01538	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IEAAGIAC_01539	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IEAAGIAC_01540	6.64e-73	-	-	-	-	-	-	-	-
IEAAGIAC_01541	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IEAAGIAC_01542	1.97e-124	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IEAAGIAC_01543	1.2e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IEAAGIAC_01544	9.12e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IEAAGIAC_01545	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IEAAGIAC_01546	2.13e-229	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IEAAGIAC_01547	8.2e-81	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
IEAAGIAC_01548	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
IEAAGIAC_01549	1.87e-218	-	-	-	K	-	-	-	LysR substrate binding domain
IEAAGIAC_01550	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IEAAGIAC_01551	5.49e-287	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IEAAGIAC_01552	4.45e-171	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IEAAGIAC_01553	8.01e-227	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IEAAGIAC_01554	3.57e-236	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IEAAGIAC_01555	8.11e-315	-	-	-	P	-	-	-	Major Facilitator Superfamily
IEAAGIAC_01556	5.9e-313	-	-	-	P	-	-	-	Major Facilitator Superfamily
IEAAGIAC_01557	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IEAAGIAC_01558	3.21e-208	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
IEAAGIAC_01559	5.92e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
IEAAGIAC_01560	6.63e-232	-	-	-	M	-	-	-	Glycosyl transferase family 8
IEAAGIAC_01561	1.4e-196	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
IEAAGIAC_01562	6.37e-185	-	-	-	I	-	-	-	Acyl-transferase
IEAAGIAC_01565	2.05e-165	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IEAAGIAC_01566	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IEAAGIAC_01567	1.15e-314	yycH	-	-	S	-	-	-	YycH protein
IEAAGIAC_01568	1.05e-186	yycI	-	-	S	-	-	-	YycH protein
IEAAGIAC_01569	2.14e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IEAAGIAC_01570	6.78e-236	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IEAAGIAC_01571	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IEAAGIAC_01572	6.57e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IEAAGIAC_01573	3.04e-313	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_01574	7.94e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IEAAGIAC_01575	5.14e-216	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IEAAGIAC_01576	6.97e-208	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IEAAGIAC_01577	2.67e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IEAAGIAC_01578	3.5e-235	ysdE	-	-	P	-	-	-	Citrate transporter
IEAAGIAC_01579	8.13e-85	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IEAAGIAC_01580	1.14e-23	-	-	-	-	-	-	-	-
IEAAGIAC_01581	2.34e-94	-	-	-	-	-	-	-	-
IEAAGIAC_01582	6.1e-69	-	-	-	-	-	-	-	-
IEAAGIAC_01584	1.26e-303	-	-	-	M	-	-	-	Glycosyl transferase
IEAAGIAC_01585	6.36e-257	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
IEAAGIAC_01586	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IEAAGIAC_01587	2.39e-226	-	-	-	L	-	-	-	HNH nucleases
IEAAGIAC_01588	5.01e-61	-	-	-	-	-	-	-	-
IEAAGIAC_01589	1.33e-174	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_01590	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IEAAGIAC_01591	8.8e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IEAAGIAC_01592	4.1e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IEAAGIAC_01593	2.41e-165	terC	-	-	P	-	-	-	Integral membrane protein TerC family
IEAAGIAC_01594	1.01e-111	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
IEAAGIAC_01595	4e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IEAAGIAC_01596	1.28e-103	-	-	-	-	-	-	-	-
IEAAGIAC_01597	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEAAGIAC_01598	5.18e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
IEAAGIAC_01599	4.79e-221	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IEAAGIAC_01600	2.67e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEAAGIAC_01601	3.75e-70	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEAAGIAC_01603	1.66e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IEAAGIAC_01604	8.79e-201	epsV	-	-	S	-	-	-	glycosyl transferase family 2
IEAAGIAC_01605	1.99e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IEAAGIAC_01606	3.25e-81	-	-	-	-	-	-	-	-
IEAAGIAC_01607	1.75e-229	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEAAGIAC_01608	1.13e-305	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IEAAGIAC_01609	3.8e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IEAAGIAC_01610	1.39e-162	-	-	-	-	-	-	-	-
IEAAGIAC_01611	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
IEAAGIAC_01612	1.3e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IEAAGIAC_01613	1.06e-132	-	-	-	-	-	-	-	-
IEAAGIAC_01614	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IEAAGIAC_01615	1.16e-215	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IEAAGIAC_01616	2.67e-154	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IEAAGIAC_01617	1.99e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IEAAGIAC_01618	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IEAAGIAC_01619	3.01e-164	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IEAAGIAC_01620	1.27e-270	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
IEAAGIAC_01621	1.47e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEAAGIAC_01622	6.53e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IEAAGIAC_01623	6.65e-190	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IEAAGIAC_01624	1.02e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IEAAGIAC_01625	1.8e-86	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IEAAGIAC_01626	1.56e-276	-	-	-	S	-	-	-	zinc-ribbon domain
IEAAGIAC_01627	1.56e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
IEAAGIAC_01628	1.02e-127	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEAAGIAC_01629	4.12e-168	-	-	-	K	-	-	-	UTRA domain
IEAAGIAC_01630	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IEAAGIAC_01631	6.03e-114	usp5	-	-	T	-	-	-	universal stress protein
IEAAGIAC_01633	1.44e-311	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IEAAGIAC_01634	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IEAAGIAC_01635	1.19e-93	-	-	-	-	-	-	-	-
IEAAGIAC_01636	2.99e-132	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IEAAGIAC_01637	0.0	-	-	-	S	-	-	-	TerB-C domain
IEAAGIAC_01638	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
IEAAGIAC_01639	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IEAAGIAC_01640	1.47e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEAAGIAC_01641	1.84e-186	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
IEAAGIAC_01642	3.97e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IEAAGIAC_01643	2.09e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
IEAAGIAC_01645	2.15e-116	-	-	-	K	-	-	-	acetyltransferase
IEAAGIAC_01646	4.37e-79	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IEAAGIAC_01647	1.15e-173	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IEAAGIAC_01648	5.02e-166	-	-	-	M	-	-	-	LysM domain protein
IEAAGIAC_01649	2.02e-183	-	-	-	M	-	-	-	LysM domain protein
IEAAGIAC_01651	2.51e-49	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
IEAAGIAC_01652	1.21e-45	-	-	-	K	-	-	-	SIS domain
IEAAGIAC_01653	3.46e-211	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
IEAAGIAC_01656	4.86e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
IEAAGIAC_01657	2.62e-244	-	-	-	-	-	-	-	-
IEAAGIAC_01658	2.57e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IEAAGIAC_01659	1.44e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
IEAAGIAC_01660	1.14e-172	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IEAAGIAC_01661	1.83e-259	-	-	-	M	-	-	-	Glycosyl transferases group 1
IEAAGIAC_01662	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IEAAGIAC_01663	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEAAGIAC_01664	9.12e-199	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IEAAGIAC_01665	0.0	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
IEAAGIAC_01666	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IEAAGIAC_01667	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IEAAGIAC_01668	4.24e-179	-	-	-	-	-	-	-	-
IEAAGIAC_01669	2.15e-284	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEAAGIAC_01670	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IEAAGIAC_01671	9.44e-170	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IEAAGIAC_01672	5.95e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IEAAGIAC_01674	4.82e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IEAAGIAC_01675	5.71e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IEAAGIAC_01676	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IEAAGIAC_01677	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IEAAGIAC_01678	3.2e-264	camS	-	-	S	-	-	-	sex pheromone
IEAAGIAC_01679	2.23e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEAAGIAC_01680	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IEAAGIAC_01681	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEAAGIAC_01682	5.13e-213	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IEAAGIAC_01684	5.66e-190	-	-	-	S	-	-	-	hydrolase
IEAAGIAC_01685	3.2e-09	-	-	-	UW	-	-	-	Tetratricopeptide repeat
IEAAGIAC_01686	2.68e-43	-	-	-	UW	-	-	-	Tetratricopeptide repeat
IEAAGIAC_01687	3.17e-98	-	-	-	UW	-	-	-	Tetratricopeptide repeat
IEAAGIAC_01688	3.42e-41	-	-	-	UW	-	-	-	Tetratricopeptide repeat
IEAAGIAC_01689	3.23e-80	-	-	-	UW	-	-	-	Tetratricopeptide repeat
IEAAGIAC_01690	8.77e-194	-	-	-	UW	-	-	-	Tetratricopeptide repeat
IEAAGIAC_01691	0.0	-	-	-	M	-	-	-	family 8
IEAAGIAC_01692	0.0	-	-	-	M	-	-	-	family 8
IEAAGIAC_01693	1.09e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IEAAGIAC_01694	1.8e-184	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IEAAGIAC_01695	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_01696	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IEAAGIAC_01697	4.91e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
IEAAGIAC_01698	2.12e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IEAAGIAC_01699	7.11e-161	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_01700	1.18e-151	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IEAAGIAC_01701	6.47e-316	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEAAGIAC_01702	4.81e-252	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IEAAGIAC_01703	2.01e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
IEAAGIAC_01704	2.82e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IEAAGIAC_01705	1.17e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IEAAGIAC_01706	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IEAAGIAC_01707	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IEAAGIAC_01708	1.56e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IEAAGIAC_01709	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IEAAGIAC_01710	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IEAAGIAC_01711	5.88e-257	-	-	-	S	-	-	-	DUF218 domain
IEAAGIAC_01712	1.62e-143	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IEAAGIAC_01713	5.32e-114	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IEAAGIAC_01716	2.11e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
IEAAGIAC_01717	3.91e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
IEAAGIAC_01718	1.13e-198	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
IEAAGIAC_01719	5.93e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IEAAGIAC_01720	3.88e-46	-	-	-	-	-	-	-	-
IEAAGIAC_01721	1.05e-193	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IEAAGIAC_01722	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IEAAGIAC_01723	1.05e-124	-	-	-	S	-	-	-	Putative adhesin
IEAAGIAC_01724	1.39e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
IEAAGIAC_01725	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IEAAGIAC_01726	1.31e-108	ykuL	-	-	S	-	-	-	(CBS) domain
IEAAGIAC_01727	6.76e-268	-	-	-	S	-	-	-	Membrane
IEAAGIAC_01728	6.13e-52	-	-	-	-	-	-	-	-
IEAAGIAC_01729	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IEAAGIAC_01730	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEAAGIAC_01731	4.7e-303	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IEAAGIAC_01732	5.16e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEAAGIAC_01733	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IEAAGIAC_01734	4.85e-187	pbpX2	-	-	V	-	-	-	Beta-lactamase
IEAAGIAC_01735	1.97e-275	-	-	-	E	-	-	-	Major Facilitator Superfamily
IEAAGIAC_01736	4.98e-52	-	-	-	-	-	-	-	-
IEAAGIAC_01737	1.23e-312	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEAAGIAC_01738	1.02e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IEAAGIAC_01739	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
IEAAGIAC_01740	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
IEAAGIAC_01741	3.08e-46	-	-	-	L	-	-	-	transposase activity
IEAAGIAC_01742	1.1e-136	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
IEAAGIAC_01743	9.96e-75	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
IEAAGIAC_01744	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IEAAGIAC_01745	2.42e-239	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IEAAGIAC_01746	3.67e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IEAAGIAC_01747	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEAAGIAC_01748	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEAAGIAC_01749	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IEAAGIAC_01750	6.51e-103	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IEAAGIAC_01751	1.39e-180	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEAAGIAC_01752	3.08e-115	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
IEAAGIAC_01753	5.9e-46	-	-	-	-	-	-	-	-
IEAAGIAC_01754	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IEAAGIAC_01755	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IEAAGIAC_01756	1.67e-291	-	-	-	G	-	-	-	Major Facilitator Superfamily
IEAAGIAC_01757	4.51e-238	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IEAAGIAC_01758	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IEAAGIAC_01759	8.06e-17	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IEAAGIAC_01760	5.22e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IEAAGIAC_01761	1.89e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IEAAGIAC_01762	2.9e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IEAAGIAC_01763	3.95e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IEAAGIAC_01764	1.83e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IEAAGIAC_01765	2.22e-185	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IEAAGIAC_01766	1.78e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IEAAGIAC_01767	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IEAAGIAC_01768	6.26e-148	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
IEAAGIAC_01770	2.71e-234	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IEAAGIAC_01771	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IEAAGIAC_01772	4.25e-220	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IEAAGIAC_01773	8.6e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
IEAAGIAC_01774	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IEAAGIAC_01775	2.21e-296	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IEAAGIAC_01776	6.63e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IEAAGIAC_01777	2.44e-303	-	-	-	E	-	-	-	amino acid
IEAAGIAC_01778	7.01e-244	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IEAAGIAC_01779	2.61e-205	-	-	-	EG	-	-	-	EamA-like transporter family
IEAAGIAC_01780	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IEAAGIAC_01781	3.43e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IEAAGIAC_01782	8.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IEAAGIAC_01783	1.34e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IEAAGIAC_01784	2.61e-235	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IEAAGIAC_01785	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IEAAGIAC_01786	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IEAAGIAC_01787	1.33e-209	-	-	-	L	-	-	-	Transposase
IEAAGIAC_01788	2.32e-39	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IEAAGIAC_01789	8.87e-185	-	-	-	M	ko:K19510	-	ko00000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IEAAGIAC_01790	1.93e-146	-	-	-	M	ko:K19504	-	ko00000	SIS domain
IEAAGIAC_01791	1.59e-163	-	-	-	G	ko:K19509	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
IEAAGIAC_01792	2.47e-139	-	-	-	G	ko:K19508	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
IEAAGIAC_01793	2.9e-77	-	-	-	G	ko:K19507	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IEAAGIAC_01794	2.72e-76	-	-	-	K	ko:K03710	-	ko00000,ko03000	DNA-binding transcription factor activity
IEAAGIAC_01795	2.28e-13	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IEAAGIAC_01796	2.83e-126	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEAAGIAC_01797	1.99e-33	-	-	-	L	-	-	-	Transposase
IEAAGIAC_01798	2.85e-151	-	-	-	L	-	-	-	Transposase
IEAAGIAC_01799	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IEAAGIAC_01800	1.28e-231	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEAAGIAC_01801	2.9e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IEAAGIAC_01802	2.71e-281	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
IEAAGIAC_01814	1.75e-80	-	-	-	-	-	-	-	-
IEAAGIAC_01831	1.53e-35	-	-	-	-	-	-	-	-
IEAAGIAC_01832	1.68e-64	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
IEAAGIAC_01833	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
IEAAGIAC_01834	1.58e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
IEAAGIAC_01835	8.98e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
IEAAGIAC_01836	2.91e-147	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IEAAGIAC_01837	1.62e-31	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IEAAGIAC_01838	1.72e-243	flp	-	-	V	-	-	-	Beta-lactamase
IEAAGIAC_01839	1.71e-195	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
IEAAGIAC_01840	1.51e-200	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IEAAGIAC_01841	1.53e-41	-	-	-	-	-	-	-	-
IEAAGIAC_01842	3.2e-54	-	-	-	-	-	-	-	-
IEAAGIAC_01845	8.26e-36	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
IEAAGIAC_01847	0.0	-	-	-	L	-	-	-	Transposase
IEAAGIAC_01848	3.49e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IEAAGIAC_01849	3.81e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region