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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
APFKBCAI_00001	0.0	-	-	-	S	-	-	-	Phage tail protein
APFKBCAI_00002	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
APFKBCAI_00003	2.33e-79	-	-	-	-	-	-	-	-
APFKBCAI_00004	3.97e-66	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
APFKBCAI_00005	1.52e-134	-	-	-	S	-	-	-	Phage tail tube protein
APFKBCAI_00006	6.75e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
APFKBCAI_00007	8.92e-75	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
APFKBCAI_00008	2.51e-62	-	-	-	-	-	-	-	-
APFKBCAI_00009	8.8e-72	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
APFKBCAI_00010	3.4e-231	gpG	-	-	-	-	-	-	-
APFKBCAI_00011	7.29e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
APFKBCAI_00012	2.94e-99	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
APFKBCAI_00013	3.5e-316	-	-	-	S	-	-	-	Phage portal protein
APFKBCAI_00014	0.0	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
APFKBCAI_00015	1.81e-110	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
APFKBCAI_00016	4.41e-68	-	-	-	-	-	-	-	-
APFKBCAI_00017	2.41e-281	-	-	-	S	-	-	-	GcrA cell cycle regulator
APFKBCAI_00018	2.71e-200	-	-	-	-	-	-	-	-
APFKBCAI_00019	1.55e-101	-	-	-	-	-	-	-	-
APFKBCAI_00022	3.71e-45	-	-	-	-	-	-	-	-
APFKBCAI_00023	1.79e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
APFKBCAI_00024	1.54e-29	-	-	-	-	-	-	-	-
APFKBCAI_00025	1.32e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
APFKBCAI_00026	1.23e-48	-	-	-	-	-	-	-	-
APFKBCAI_00027	4.02e-89	-	-	-	-	-	-	-	-
APFKBCAI_00028	4.62e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APFKBCAI_00029	2.85e-97	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APFKBCAI_00030	6.05e-204	-	-	-	L	-	-	-	Replication initiation and membrane attachment
APFKBCAI_00031	8.62e-171	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
APFKBCAI_00032	3.83e-198	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
APFKBCAI_00035	2.86e-20	-	-	-	-	-	-	-	-
APFKBCAI_00037	3.67e-126	-	-	-	-	-	-	-	-
APFKBCAI_00038	4.05e-97	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
APFKBCAI_00040	3.62e-46	-	-	-	K	-	-	-	Helix-turn-helix domain
APFKBCAI_00041	2.45e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
APFKBCAI_00042	3.3e-97	-	-	-	E	-	-	-	Zn peptidase
APFKBCAI_00043	1.19e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
APFKBCAI_00044	3.79e-226	-	-	-	-	-	-	-	-
APFKBCAI_00046	1.21e-287	-	-	-	L	-	-	-	Pfam:Integrase_AP2
APFKBCAI_00047	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
APFKBCAI_00048	1.1e-194	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
APFKBCAI_00049	3.74e-142	vanZ	-	-	V	-	-	-	VanZ like family
APFKBCAI_00050	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APFKBCAI_00051	3.36e-166	-	-	-	-	-	-	-	-
APFKBCAI_00052	4.26e-133	-	-	-	-	-	-	-	-
APFKBCAI_00053	5.79e-316	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APFKBCAI_00054	2.43e-263	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APFKBCAI_00055	5.34e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
APFKBCAI_00056	6.51e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APFKBCAI_00057	1.51e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
APFKBCAI_00058	4.85e-106	yvbK	-	-	K	-	-	-	GNAT family
APFKBCAI_00059	3.64e-37	-	-	-	T	-	-	-	PFAM SpoVT AbrB
APFKBCAI_00060	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
APFKBCAI_00061	9.9e-216	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
APFKBCAI_00062	5.01e-142	-	-	-	-	-	-	-	-
APFKBCAI_00063	1.22e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
APFKBCAI_00064	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APFKBCAI_00065	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
APFKBCAI_00066	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_00068	9.26e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
APFKBCAI_00069	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
APFKBCAI_00070	8.56e-157	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
APFKBCAI_00071	2.12e-40	-	-	-	-	-	-	-	-
APFKBCAI_00073	2.66e-247	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APFKBCAI_00074	4.73e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
APFKBCAI_00075	3.71e-105	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
APFKBCAI_00076	2.47e-227	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
APFKBCAI_00077	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
APFKBCAI_00078	3.46e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_00079	5.51e-304	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
APFKBCAI_00080	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APFKBCAI_00081	1.66e-07	-	-	-	-	-	-	-	-
APFKBCAI_00083	3.16e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
APFKBCAI_00084	1.19e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APFKBCAI_00085	6.94e-299	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
APFKBCAI_00086	1.55e-226	mocA	-	-	S	-	-	-	Oxidoreductase
APFKBCAI_00087	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
APFKBCAI_00088	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
APFKBCAI_00089	2.7e-173	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
APFKBCAI_00090	1.05e-40	-	-	-	-	-	-	-	-
APFKBCAI_00091	7.91e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
APFKBCAI_00092	2.75e-211	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
APFKBCAI_00093	6.68e-98	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_00094	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
APFKBCAI_00095	4.22e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
APFKBCAI_00096	4.65e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APFKBCAI_00097	1.24e-240	yttB	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_00098	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APFKBCAI_00099	1.22e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
APFKBCAI_00100	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APFKBCAI_00101	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APFKBCAI_00102	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APFKBCAI_00103	2.36e-260	camS	-	-	S	-	-	-	sex pheromone
APFKBCAI_00104	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APFKBCAI_00105	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
APFKBCAI_00106	1.92e-53	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
APFKBCAI_00107	2.35e-169	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
APFKBCAI_00108	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APFKBCAI_00109	1e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APFKBCAI_00110	1.59e-215	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
APFKBCAI_00111	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_00112	2.13e-115	-	-	-	-	-	-	-	-
APFKBCAI_00113	5.11e-149	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
APFKBCAI_00114	1.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APFKBCAI_00115	5.18e-75	-	-	-	-	-	-	-	-
APFKBCAI_00116	9.07e-61	-	-	-	-	-	-	-	-
APFKBCAI_00117	1.66e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
APFKBCAI_00118	2.17e-213	-	-	-	K	-	-	-	LysR substrate binding domain
APFKBCAI_00119	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APFKBCAI_00120	8.09e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
APFKBCAI_00121	1.45e-162	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
APFKBCAI_00122	5.58e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
APFKBCAI_00124	1.24e-79	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_00126	1.5e-31	-	-	-	-	-	-	-	-
APFKBCAI_00128	1.71e-17	-	-	-	-	-	-	-	-
APFKBCAI_00129	3.33e-78	-	-	-	-	-	-	-	-
APFKBCAI_00130	1.32e-183	-	-	-	S	-	-	-	hydrolase
APFKBCAI_00131	6.23e-244	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
APFKBCAI_00132	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
APFKBCAI_00133	4.69e-94	-	-	-	K	-	-	-	MarR family
APFKBCAI_00134	1.32e-137	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
APFKBCAI_00135	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APFKBCAI_00137	1.49e-139	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APFKBCAI_00138	1.95e-223	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
APFKBCAI_00139	1.1e-189	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
APFKBCAI_00140	0.0	-	-	-	L	-	-	-	DNA helicase
APFKBCAI_00141	1.08e-168	-	-	-	L	-	-	-	DNA helicase
APFKBCAI_00142	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APFKBCAI_00143	4.27e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00144	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
APFKBCAI_00146	2.48e-150	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_00148	5.19e-32	-	-	-	-	-	-	-	-
APFKBCAI_00149	2.4e-104	-	-	-	-	-	-	-	-
APFKBCAI_00150	6.02e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APFKBCAI_00151	4.87e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
APFKBCAI_00152	6.41e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
APFKBCAI_00153	1.3e-302	dinF	-	-	V	-	-	-	MatE
APFKBCAI_00154	2.77e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
APFKBCAI_00155	2.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
APFKBCAI_00156	1.95e-221	ydhF	-	-	S	-	-	-	Aldo keto reductase
APFKBCAI_00157	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APFKBCAI_00158	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APFKBCAI_00159	5.8e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
APFKBCAI_00160	3.46e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
APFKBCAI_00161	3.78e-51	-	-	-	-	-	-	-	-
APFKBCAI_00162	5.54e-126	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
APFKBCAI_00163	8.88e-217	-	-	-	-	-	-	-	-
APFKBCAI_00164	7.77e-25	-	-	-	-	-	-	-	-
APFKBCAI_00165	3.42e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
APFKBCAI_00166	5.76e-140	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
APFKBCAI_00167	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
APFKBCAI_00168	9.01e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
APFKBCAI_00169	2.42e-195	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
APFKBCAI_00170	4.67e-222	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APFKBCAI_00171	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APFKBCAI_00172	3.43e-85	-	-	-	-	-	-	-	-
APFKBCAI_00173	9.64e-42	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
APFKBCAI_00174	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APFKBCAI_00175	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APFKBCAI_00176	2.86e-215	-	-	-	T	-	-	-	GHKL domain
APFKBCAI_00177	2.89e-160	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
APFKBCAI_00178	5.82e-219	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
APFKBCAI_00179	4.53e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
APFKBCAI_00180	6.1e-81	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
APFKBCAI_00181	3.71e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
APFKBCAI_00182	2.76e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APFKBCAI_00183	6.29e-194	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APFKBCAI_00184	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
APFKBCAI_00185	4.38e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APFKBCAI_00186	6.67e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
APFKBCAI_00187	2.5e-159	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
APFKBCAI_00188	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00189	5.87e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
APFKBCAI_00190	1.3e-281	ysaA	-	-	V	-	-	-	RDD family
APFKBCAI_00192	2.22e-297	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APFKBCAI_00193	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APFKBCAI_00194	1.34e-68	nudA	-	-	S	-	-	-	ASCH
APFKBCAI_00195	1.36e-94	-	-	-	-	-	-	-	-
APFKBCAI_00196	1.4e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APFKBCAI_00197	2.05e-235	-	-	-	S	-	-	-	DUF218 domain
APFKBCAI_00198	6.22e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
APFKBCAI_00199	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
APFKBCAI_00200	2.83e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
APFKBCAI_00201	1.72e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
APFKBCAI_00202	6.95e-99	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APFKBCAI_00203	4.28e-195	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
APFKBCAI_00206	9.47e-281	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
APFKBCAI_00207	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APFKBCAI_00209	3.66e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APFKBCAI_00210	1.56e-24	-	-	-	-	-	-	-	-
APFKBCAI_00219	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
APFKBCAI_00220	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APFKBCAI_00221	1.76e-104	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APFKBCAI_00222	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APFKBCAI_00223	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APFKBCAI_00224	4.04e-109	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
APFKBCAI_00225	0.0	-	-	-	M	-	-	-	domain protein
APFKBCAI_00226	1.29e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APFKBCAI_00227	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APFKBCAI_00228	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APFKBCAI_00229	6.08e-253	-	-	-	K	-	-	-	WYL domain
APFKBCAI_00230	5.85e-139	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
APFKBCAI_00231	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
APFKBCAI_00232	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
APFKBCAI_00233	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APFKBCAI_00234	3.43e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
APFKBCAI_00235	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APFKBCAI_00236	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APFKBCAI_00237	6.95e-21	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APFKBCAI_00238	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APFKBCAI_00239	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APFKBCAI_00240	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APFKBCAI_00241	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
APFKBCAI_00242	9.86e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APFKBCAI_00243	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APFKBCAI_00244	4.8e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APFKBCAI_00245	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APFKBCAI_00246	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APFKBCAI_00247	3.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APFKBCAI_00248	5.63e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APFKBCAI_00249	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APFKBCAI_00250	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
APFKBCAI_00251	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
APFKBCAI_00252	1.63e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APFKBCAI_00253	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APFKBCAI_00254	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APFKBCAI_00255	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
APFKBCAI_00256	3.78e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APFKBCAI_00257	3.14e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APFKBCAI_00258	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APFKBCAI_00259	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
APFKBCAI_00260	3.15e-153	-	-	-	-	-	-	-	-
APFKBCAI_00261	7.77e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APFKBCAI_00262	5.02e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APFKBCAI_00263	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APFKBCAI_00264	3.99e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APFKBCAI_00266	7.1e-175	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
APFKBCAI_00267	1.28e-45	-	-	-	-	-	-	-	-
APFKBCAI_00268	4.28e-163	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_00269	1.06e-237	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
APFKBCAI_00270	4.31e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_00271	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APFKBCAI_00272	3.01e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
APFKBCAI_00273	2.52e-264	-	-	-	EGP	-	-	-	Transmembrane secretion effector
APFKBCAI_00274	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
APFKBCAI_00275	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APFKBCAI_00277	2.13e-18	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
APFKBCAI_00279	1.29e-157	-	-	-	S	-	-	-	B3/4 domain
APFKBCAI_00280	3.4e-189	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APFKBCAI_00281	2.36e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_00282	2.41e-299	-	-	-	I	-	-	-	Acyltransferase family
APFKBCAI_00283	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
APFKBCAI_00284	3.74e-217	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
APFKBCAI_00285	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
APFKBCAI_00286	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
APFKBCAI_00287	2.53e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APFKBCAI_00288	1.35e-69	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APFKBCAI_00290	2.99e-27	-	-	-	-	-	-	-	-
APFKBCAI_00291	1.64e-208	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APFKBCAI_00292	8.81e-112	-	-	-	-	-	-	-	-
APFKBCAI_00293	1.64e-151	-	-	-	GM	-	-	-	NmrA-like family
APFKBCAI_00294	2.35e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APFKBCAI_00295	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APFKBCAI_00296	4.8e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APFKBCAI_00297	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
APFKBCAI_00298	1.55e-224	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
APFKBCAI_00299	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
APFKBCAI_00300	5.65e-143	-	-	-	P	-	-	-	Cation efflux family
APFKBCAI_00301	2.5e-34	-	-	-	-	-	-	-	-
APFKBCAI_00302	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
APFKBCAI_00303	1.61e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APFKBCAI_00304	4.42e-84	-	-	-	-	-	-	-	-
APFKBCAI_00305	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
APFKBCAI_00306	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
APFKBCAI_00307	2.61e-25	-	-	-	-	-	-	-	-
APFKBCAI_00309	4.92e-243	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APFKBCAI_00310	1.17e-57	-	-	-	-	-	-	-	-
APFKBCAI_00311	9.29e-138	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APFKBCAI_00312	0.0	-	-	-	-	-	-	-	-
APFKBCAI_00314	4.74e-176	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APFKBCAI_00315	2.83e-241	ynjC	-	-	S	-	-	-	Cell surface protein
APFKBCAI_00316	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
APFKBCAI_00317	1.86e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
APFKBCAI_00318	8.37e-76	-	-	-	-	-	-	-	-
APFKBCAI_00319	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
APFKBCAI_00320	4.17e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APFKBCAI_00321	3.65e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
APFKBCAI_00322	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
APFKBCAI_00323	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APFKBCAI_00324	1.27e-308	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_00325	3.89e-203	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
APFKBCAI_00326	1.39e-174	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
APFKBCAI_00327	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_00328	3.57e-28	-	-	-	-	-	-	-	-
APFKBCAI_00330	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
APFKBCAI_00331	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APFKBCAI_00332	8.11e-116	-	-	-	-	-	-	-	-
APFKBCAI_00333	2.92e-144	-	-	-	-	-	-	-	-
APFKBCAI_00334	2.37e-164	-	-	-	-	-	-	-	-
APFKBCAI_00335	9.36e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_00336	7.37e-96	-	-	-	-	-	-	-	-
APFKBCAI_00337	2.06e-103	-	-	-	S	-	-	-	NUDIX domain
APFKBCAI_00338	2.66e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
APFKBCAI_00339	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
APFKBCAI_00340	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
APFKBCAI_00341	1.25e-149	-	-	-	-	-	-	-	-
APFKBCAI_00342	3.49e-306	-	-	-	S	ko:K06872	-	ko00000	TPM domain
APFKBCAI_00343	2.86e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
APFKBCAI_00344	1.85e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
APFKBCAI_00345	1.47e-07	-	-	-	-	-	-	-	-
APFKBCAI_00346	8.87e-85	-	-	-	-	-	-	-	-
APFKBCAI_00347	2.59e-69	-	-	-	-	-	-	-	-
APFKBCAI_00348	2.23e-107	-	-	-	C	-	-	-	Flavodoxin
APFKBCAI_00349	4.57e-49	-	-	-	-	-	-	-	-
APFKBCAI_00350	1.99e-36	-	-	-	-	-	-	-	-
APFKBCAI_00351	1.22e-220	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APFKBCAI_00352	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
APFKBCAI_00353	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
APFKBCAI_00354	9.7e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
APFKBCAI_00355	1.32e-39	-	-	-	-	-	-	-	-
APFKBCAI_00356	1.62e-80	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APFKBCAI_00357	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APFKBCAI_00358	2.16e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
APFKBCAI_00359	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
APFKBCAI_00360	5.63e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
APFKBCAI_00361	6.93e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APFKBCAI_00362	4.85e-136	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
APFKBCAI_00364	3.57e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
APFKBCAI_00365	2.32e-86	-	-	-	-	-	-	-	-
APFKBCAI_00366	2.13e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
APFKBCAI_00367	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APFKBCAI_00368	3.67e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
APFKBCAI_00369	6.39e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
APFKBCAI_00370	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
APFKBCAI_00371	4.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APFKBCAI_00372	3.39e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
APFKBCAI_00373	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APFKBCAI_00374	1.22e-154	-	-	-	-	-	-	-	-
APFKBCAI_00375	1.68e-156	vanR	-	-	K	-	-	-	response regulator
APFKBCAI_00376	1.19e-279	hpk31	-	-	T	-	-	-	Histidine kinase
APFKBCAI_00377	5.54e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
APFKBCAI_00378	5.76e-108	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APFKBCAI_00379	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APFKBCAI_00380	3.16e-181	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
APFKBCAI_00381	2.26e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
APFKBCAI_00382	1.96e-182	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
APFKBCAI_00383	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APFKBCAI_00384	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
APFKBCAI_00385	5.96e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APFKBCAI_00386	1.88e-226	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APFKBCAI_00387	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APFKBCAI_00388	1.12e-245	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APFKBCAI_00389	1.01e-250	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
APFKBCAI_00390	6.04e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APFKBCAI_00391	8.12e-204	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APFKBCAI_00392	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
APFKBCAI_00393	2.07e-204	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
APFKBCAI_00394	2.87e-213	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
APFKBCAI_00395	3.12e-187	gntR	-	-	K	-	-	-	rpiR family
APFKBCAI_00396	2.45e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
APFKBCAI_00397	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
APFKBCAI_00398	1.17e-189	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APFKBCAI_00399	5.37e-249	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
APFKBCAI_00400	5.83e-224	-	-	-	-	-	-	-	-
APFKBCAI_00401	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
APFKBCAI_00402	1.61e-24	-	-	-	-	-	-	-	-
APFKBCAI_00403	7.64e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_00404	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
APFKBCAI_00405	5.78e-133	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
APFKBCAI_00406	5.73e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
APFKBCAI_00407	2.49e-100	-	-	-	O	-	-	-	OsmC-like protein
APFKBCAI_00409	0.0	-	-	-	L	-	-	-	Exonuclease
APFKBCAI_00410	5.54e-07	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
APFKBCAI_00411	1.38e-41	-	-	-	L	-	-	-	RelB antitoxin
APFKBCAI_00412	1.04e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
APFKBCAI_00413	3.3e-261	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
APFKBCAI_00414	8.46e-177	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APFKBCAI_00415	5.78e-156	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
APFKBCAI_00416	4.15e-77	ydfF	-	-	K	-	-	-	Transcriptional
APFKBCAI_00417	5.79e-132	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
APFKBCAI_00418	8.09e-44	-	-	-	-	-	-	-	-
APFKBCAI_00419	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
APFKBCAI_00420	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
APFKBCAI_00421	2.39e-60	-	-	-	-	-	-	-	-
APFKBCAI_00422	6.33e-192	pbpE	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_00423	2.87e-248	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
APFKBCAI_00424	6.38e-178	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
APFKBCAI_00425	4.13e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
APFKBCAI_00426	1.35e-134	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
APFKBCAI_00427	5.97e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
APFKBCAI_00428	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
APFKBCAI_00429	5.28e-284	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
APFKBCAI_00430	2.77e-316	-	-	-	E	-	-	-	Amino acid permease
APFKBCAI_00431	4.17e-97	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APFKBCAI_00432	1.31e-208	-	-	-	S	-	-	-	reductase
APFKBCAI_00433	2.67e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
APFKBCAI_00434	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
APFKBCAI_00435	2.64e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APFKBCAI_00436	3.13e-255	-	-	-	-	-	-	-	-
APFKBCAI_00437	8.61e-167	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_00438	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
APFKBCAI_00439	1.15e-162	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
APFKBCAI_00440	2.7e-258	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APFKBCAI_00441	4.67e-203	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
APFKBCAI_00442	4.63e-255	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
APFKBCAI_00443	8.65e-136	-	-	-	-	-	-	-	-
APFKBCAI_00445	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
APFKBCAI_00446	0.0	ycaM	-	-	E	-	-	-	amino acid
APFKBCAI_00447	1.79e-303	xylP	-	-	G	-	-	-	MFS/sugar transport protein
APFKBCAI_00448	1.87e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
APFKBCAI_00449	3.9e-208	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
APFKBCAI_00450	4.43e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
APFKBCAI_00452	1.28e-179	-	-	-	-	-	-	-	-
APFKBCAI_00454	2.88e-271	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
APFKBCAI_00455	1.61e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
APFKBCAI_00456	3.91e-155	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_00457	2.12e-173	-	-	-	-	-	-	-	-
APFKBCAI_00458	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
APFKBCAI_00459	2.81e-132	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APFKBCAI_00460	9.66e-228	-	-	-	S	-	-	-	Cell surface protein
APFKBCAI_00461	5.86e-65	-	-	-	-	-	-	-	-
APFKBCAI_00462	1.95e-237	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
APFKBCAI_00463	1.08e-214	yicL	-	-	EG	-	-	-	EamA-like transporter family
APFKBCAI_00464	0.0	-	-	-	-	-	-	-	-
APFKBCAI_00465	2.12e-182	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_00466	2.12e-100	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
APFKBCAI_00467	5e-194	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_00468	0.0	-	-	-	-	-	-	-	-
APFKBCAI_00469	2.18e-221	-	-	-	-	-	-	-	-
APFKBCAI_00470	9.09e-82	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
APFKBCAI_00471	1.83e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_00472	7.23e-89	-	-	-	-	-	-	-	-
APFKBCAI_00473	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
APFKBCAI_00474	5.37e-106	-	-	-	-	-	-	-	-
APFKBCAI_00475	3.99e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
APFKBCAI_00476	5.59e-290	-	-	-	E	-	-	-	Amino acid permease
APFKBCAI_00477	2.14e-118	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APFKBCAI_00478	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APFKBCAI_00479	2.89e-110	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
APFKBCAI_00480	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APFKBCAI_00481	1.89e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
APFKBCAI_00482	1.73e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APFKBCAI_00483	5.65e-149	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
APFKBCAI_00484	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APFKBCAI_00485	1.03e-303	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
APFKBCAI_00486	5.92e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
APFKBCAI_00487	2.01e-151	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
APFKBCAI_00488	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
APFKBCAI_00489	6.56e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
APFKBCAI_00490	2.04e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
APFKBCAI_00491	1.28e-146	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APFKBCAI_00492	4.99e-181	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
APFKBCAI_00493	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_00494	7.44e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
APFKBCAI_00495	3.16e-31	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
APFKBCAI_00496	2.08e-146	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
APFKBCAI_00497	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APFKBCAI_00498	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
APFKBCAI_00499	4.54e-12	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APFKBCAI_00500	1.49e-70	-	-	-	-	-	-	-	-
APFKBCAI_00501	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
APFKBCAI_00502	5.56e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APFKBCAI_00503	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
APFKBCAI_00504	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
APFKBCAI_00505	1.82e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APFKBCAI_00506	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APFKBCAI_00507	1.56e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APFKBCAI_00508	4.67e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APFKBCAI_00509	2.11e-307	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APFKBCAI_00510	1.09e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APFKBCAI_00511	5.95e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APFKBCAI_00512	6.86e-60	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
APFKBCAI_00513	1.91e-185	ylmH	-	-	S	-	-	-	S4 domain protein
APFKBCAI_00514	8.06e-114	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
APFKBCAI_00515	9.84e-124	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APFKBCAI_00516	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APFKBCAI_00517	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
APFKBCAI_00518	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
APFKBCAI_00519	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_00520	6e-268	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
APFKBCAI_00521	1.39e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
APFKBCAI_00522	6.34e-127	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
APFKBCAI_00523	1.36e-46	-	-	-	-	-	-	-	-
APFKBCAI_00524	3.94e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APFKBCAI_00525	8.18e-53	-	-	-	-	-	-	-	-
APFKBCAI_00526	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
APFKBCAI_00527	6.18e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APFKBCAI_00528	9.73e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
APFKBCAI_00529	8.1e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
APFKBCAI_00530	2.14e-36	-	-	-	-	-	-	-	-
APFKBCAI_00531	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
APFKBCAI_00532	9.59e-101	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
APFKBCAI_00533	1.76e-284	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APFKBCAI_00534	1.72e-243	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
APFKBCAI_00535	2.4e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
APFKBCAI_00536	7.93e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_00537	1.03e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APFKBCAI_00538	5.03e-191	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APFKBCAI_00541	1.56e-189	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
APFKBCAI_00542	2.29e-252	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
APFKBCAI_00543	2.34e-62	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
APFKBCAI_00544	1.35e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
APFKBCAI_00545	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
APFKBCAI_00546	1.62e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
APFKBCAI_00547	5.48e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
APFKBCAI_00548	8.67e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
APFKBCAI_00549	2.5e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
APFKBCAI_00550	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
APFKBCAI_00551	6.58e-100	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APFKBCAI_00552	2.28e-175	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APFKBCAI_00553	2.47e-12	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
APFKBCAI_00554	1.2e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APFKBCAI_00555	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APFKBCAI_00556	3.77e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APFKBCAI_00557	1.03e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APFKBCAI_00558	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APFKBCAI_00559	2.38e-160	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
APFKBCAI_00560	2.46e-127	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APFKBCAI_00561	5.24e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APFKBCAI_00562	1.73e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APFKBCAI_00563	9.85e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APFKBCAI_00564	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APFKBCAI_00565	8.22e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
APFKBCAI_00566	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
APFKBCAI_00567	1.72e-243	ampC	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_00568	1.31e-208	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
APFKBCAI_00569	1.24e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
APFKBCAI_00570	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
APFKBCAI_00571	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00572	1.29e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_00573	5.42e-170	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
APFKBCAI_00576	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APFKBCAI_00577	4.62e-246	yttB	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_00578	1.56e-25	-	-	-	-	-	-	-	-
APFKBCAI_00581	3.9e-13	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APFKBCAI_00582	6.11e-216	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APFKBCAI_00587	2.6e-106	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
APFKBCAI_00588	4.43e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
APFKBCAI_00589	2.76e-294	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
APFKBCAI_00590	6.23e-106	-	-	-	S	-	-	-	Pfam Transposase IS66
APFKBCAI_00591	8.47e-182	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
APFKBCAI_00592	4.12e-61	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APFKBCAI_00594	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_00595	6.4e-244	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
APFKBCAI_00596	1.31e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APFKBCAI_00597	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_00598	0.0	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APFKBCAI_00599	8.52e-253	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APFKBCAI_00600	7.98e-295	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
APFKBCAI_00601	2.4e-279	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
APFKBCAI_00602	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APFKBCAI_00603	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APFKBCAI_00604	2.63e-207	-	-	-	-	-	-	-	-
APFKBCAI_00605	8.14e-63	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_00606	4.02e-111	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_00607	1.74e-308	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_00608	9.78e-189	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	KR domain
APFKBCAI_00609	7.95e-222	lacC	2.7.1.144	-	F	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
APFKBCAI_00610	3.18e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
APFKBCAI_00611	1.23e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APFKBCAI_00612	2.07e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APFKBCAI_00613	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APFKBCAI_00614	5.49e-284	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
APFKBCAI_00615	6.85e-154	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
APFKBCAI_00616	5.31e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APFKBCAI_00617	1.15e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
APFKBCAI_00618	1.33e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
APFKBCAI_00619	1.66e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
APFKBCAI_00620	4.97e-111	-	-	-	-	-	-	-	-
APFKBCAI_00621	1.94e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
APFKBCAI_00622	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
APFKBCAI_00623	9.33e-153	-	-	-	-	-	-	-	-
APFKBCAI_00624	5.09e-203	-	-	-	-	-	-	-	-
APFKBCAI_00625	2.1e-295	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APFKBCAI_00626	3.11e-75	lacF-1	2.7.1.207	-	G	ko:K02786	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APFKBCAI_00627	5.96e-185	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
APFKBCAI_00628	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
APFKBCAI_00629	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
APFKBCAI_00630	1.09e-217	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
APFKBCAI_00631	1.23e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
APFKBCAI_00632	1.13e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
APFKBCAI_00633	7.73e-146	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APFKBCAI_00634	2.48e-82	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APFKBCAI_00635	3.25e-207	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APFKBCAI_00636	5.12e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APFKBCAI_00637	4.89e-70	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
APFKBCAI_00638	2.36e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_00639	5.83e-178	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
APFKBCAI_00640	8.13e-185	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
APFKBCAI_00641	6.02e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
APFKBCAI_00642	4.62e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
APFKBCAI_00643	1.7e-96	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
APFKBCAI_00644	1.14e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
APFKBCAI_00645	1.46e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APFKBCAI_00647	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
APFKBCAI_00648	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
APFKBCAI_00649	1.05e-251	-	-	-	-	-	-	-	-
APFKBCAI_00650	7.65e-272	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APFKBCAI_00651	1.21e-210	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_00652	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
APFKBCAI_00653	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
APFKBCAI_00654	2.36e-119	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
APFKBCAI_00655	9.8e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APFKBCAI_00656	1.56e-256	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
APFKBCAI_00657	5.45e-61	-	-	-	-	-	-	-	-
APFKBCAI_00658	5.21e-229	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
APFKBCAI_00659	5.54e-23	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
APFKBCAI_00660	9.49e-26	-	-	-	S	-	-	-	CsbD-like
APFKBCAI_00661	1.01e-190	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
APFKBCAI_00662	3.49e-242	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
APFKBCAI_00663	2.35e-145	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
APFKBCAI_00664	2.15e-215	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
APFKBCAI_00665	1.01e-119	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
APFKBCAI_00667	2.13e-44	-	-	-	-	-	-	-	-
APFKBCAI_00668	6.67e-46	-	-	-	-	-	-	-	-
APFKBCAI_00669	1.41e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
APFKBCAI_00670	1.37e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APFKBCAI_00671	4.13e-191	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APFKBCAI_00673	1.09e-117	-	-	-	-	-	-	-	-
APFKBCAI_00674	3.66e-36	-	-	-	V	-	-	-	MacB-like periplasmic core domain
APFKBCAI_00675	1.16e-69	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00677	4.95e-181	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
APFKBCAI_00678	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
APFKBCAI_00679	0.0	-	-	-	M	-	-	-	domain protein
APFKBCAI_00680	0.0	-	-	-	M	-	-	-	domain protein
APFKBCAI_00681	1.81e-132	-	-	-	-	-	-	-	-
APFKBCAI_00682	2.19e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APFKBCAI_00683	7.18e-281	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
APFKBCAI_00684	2.42e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
APFKBCAI_00685	1.49e-123	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APFKBCAI_00686	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
APFKBCAI_00687	6.8e-177	-	-	-	-	-	-	-	-
APFKBCAI_00688	2.36e-171	-	-	-	-	-	-	-	-
APFKBCAI_00689	2.47e-58	-	-	-	S	-	-	-	Enterocin A Immunity
APFKBCAI_00690	2.53e-236	tas	-	-	C	-	-	-	Aldo/keto reductase family
APFKBCAI_00691	2.29e-146	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APFKBCAI_00692	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
APFKBCAI_00693	2.93e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
APFKBCAI_00694	1.12e-82	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
APFKBCAI_00695	1.14e-168	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
APFKBCAI_00696	5.68e-109	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
APFKBCAI_00697	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APFKBCAI_00698	4.87e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
APFKBCAI_00699	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APFKBCAI_00700	1.6e-150	-	-	-	-	-	-	-	-
APFKBCAI_00701	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APFKBCAI_00702	1.01e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
APFKBCAI_00703	2.02e-247	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
APFKBCAI_00704	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
APFKBCAI_00705	3.25e-146	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
APFKBCAI_00706	1.01e-247	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
APFKBCAI_00707	2.44e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APFKBCAI_00708	1.01e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
APFKBCAI_00709	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
APFKBCAI_00710	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APFKBCAI_00711	3.76e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
APFKBCAI_00712	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
APFKBCAI_00713	1.06e-186	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
APFKBCAI_00714	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
APFKBCAI_00715	2.05e-200	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
APFKBCAI_00716	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
APFKBCAI_00717	1.87e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APFKBCAI_00718	4.67e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
APFKBCAI_00719	1.36e-265	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
APFKBCAI_00720	1.64e-173	-	-	-	S	-	-	-	E1-E2 ATPase
APFKBCAI_00721	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APFKBCAI_00722	1.83e-35	-	-	-	-	-	-	-	-
APFKBCAI_00723	2.52e-97	-	-	-	-	-	-	-	-
APFKBCAI_00725	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
APFKBCAI_00726	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APFKBCAI_00727	5.85e-61	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
APFKBCAI_00728	2.06e-148	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
APFKBCAI_00729	1.36e-310	-	-	-	S	-	-	-	Sterol carrier protein domain
APFKBCAI_00730	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APFKBCAI_00731	3.38e-149	-	-	-	S	-	-	-	repeat protein
APFKBCAI_00732	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
APFKBCAI_00733	1.39e-276	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APFKBCAI_00734	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
APFKBCAI_00735	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
APFKBCAI_00736	9.75e-175	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
APFKBCAI_00737	0.0	-	-	-	S	-	-	-	ABC transporter
APFKBCAI_00738	2.19e-219	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
APFKBCAI_00739	1.45e-136	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
APFKBCAI_00740	9.9e-69	-	-	-	-	-	-	-	-
APFKBCAI_00741	9.02e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
APFKBCAI_00742	1.34e-187	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APFKBCAI_00743	2.29e-175	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
APFKBCAI_00744	3.02e-99	-	-	-	T	-	-	-	Sh3 type 3 domain protein
APFKBCAI_00745	7.52e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
APFKBCAI_00746	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APFKBCAI_00747	2.6e-150	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
APFKBCAI_00748	6.46e-262	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
APFKBCAI_00749	4.74e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
APFKBCAI_00750	3.1e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
APFKBCAI_00751	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
APFKBCAI_00752	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APFKBCAI_00753	1.85e-75	-	-	-	-	-	-	-	-
APFKBCAI_00754	2.29e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
APFKBCAI_00755	4.46e-07	-	-	-	-	-	-	-	-
APFKBCAI_00756	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
APFKBCAI_00757	3.66e-183	yycI	-	-	S	-	-	-	YycH protein
APFKBCAI_00758	0.0	yycH	-	-	S	-	-	-	YycH protein
APFKBCAI_00759	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APFKBCAI_00760	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
APFKBCAI_00761	2.14e-157	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
APFKBCAI_00762	4.89e-95	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_00763	1.08e-193	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_00764	4.66e-298	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
APFKBCAI_00765	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
APFKBCAI_00766	3.77e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
APFKBCAI_00767	3.7e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
APFKBCAI_00768	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APFKBCAI_00769	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
APFKBCAI_00770	2.7e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_00771	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
APFKBCAI_00772	3.03e-139	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_00773	2.67e-104	-	-	-	F	-	-	-	NUDIX domain
APFKBCAI_00774	1.7e-117	-	-	-	S	-	-	-	AAA domain
APFKBCAI_00775	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
APFKBCAI_00776	3.1e-243	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APFKBCAI_00777	1.07e-52	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APFKBCAI_00778	3.01e-273	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
APFKBCAI_00779	7.35e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
APFKBCAI_00780	2.19e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
APFKBCAI_00781	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
APFKBCAI_00782	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
APFKBCAI_00783	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APFKBCAI_00784	5.9e-280	-	-	-	EGP	-	-	-	Major facilitator Superfamily
APFKBCAI_00785	2.33e-239	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
APFKBCAI_00786	5.87e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APFKBCAI_00787	2.41e-201	-	-	-	K	-	-	-	sequence-specific DNA binding
APFKBCAI_00791	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
APFKBCAI_00792	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_00793	3.81e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00794	2.19e-52	-	-	-	-	-	-	-	-
APFKBCAI_00795	1.93e-302	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
APFKBCAI_00796	9e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
APFKBCAI_00797	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
APFKBCAI_00798	9.87e-70	-	-	-	-	-	-	-	-
APFKBCAI_00799	1.9e-104	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
APFKBCAI_00800	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
APFKBCAI_00801	5.46e-186	-	-	-	S	-	-	-	AAA ATPase domain
APFKBCAI_00802	1.73e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
APFKBCAI_00803	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00804	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_00805	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_00806	1.33e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APFKBCAI_00807	2.9e-133	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
APFKBCAI_00808	1.84e-211	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
APFKBCAI_00809	1.59e-168	-	-	-	S	-	-	-	Protein of unknown function DUF58
APFKBCAI_00810	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
APFKBCAI_00811	7.06e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
APFKBCAI_00812	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
APFKBCAI_00813	4.25e-144	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
APFKBCAI_00814	9.76e-83	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
APFKBCAI_00817	9.57e-252	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
APFKBCAI_00818	5.16e-290	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
APFKBCAI_00819	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
APFKBCAI_00820	1.74e-154	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
APFKBCAI_00821	4.64e-129	-	-	-	-	-	-	-	-
APFKBCAI_00822	5.58e-22	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APFKBCAI_00823	3.39e-193	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
APFKBCAI_00824	3.93e-90	-	-	-	-	-	-	-	-
APFKBCAI_00825	4.52e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
APFKBCAI_00826	7.89e-216	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APFKBCAI_00827	1.67e-286	-	-	-	G	-	-	-	phosphotransferase system
APFKBCAI_00828	4.14e-127	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
APFKBCAI_00830	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APFKBCAI_00831	1.97e-46	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
APFKBCAI_00832	4.69e-151	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
APFKBCAI_00833	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
APFKBCAI_00834	1.75e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
APFKBCAI_00835	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APFKBCAI_00836	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
APFKBCAI_00837	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_00838	2.92e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APFKBCAI_00839	9.1e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
APFKBCAI_00840	7.2e-60	-	-	-	-	-	-	-	-
APFKBCAI_00841	1.29e-25	-	-	-	-	-	-	-	-
APFKBCAI_00842	2.47e-175	-	-	-	-	-	-	-	-
APFKBCAI_00843	3.3e-280	-	-	-	K	-	-	-	IrrE N-terminal-like domain
APFKBCAI_00844	6.5e-197	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APFKBCAI_00845	2.05e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_00846	2.73e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
APFKBCAI_00847	9.47e-234	-	-	-	-	-	-	-	-
APFKBCAI_00848	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
APFKBCAI_00849	1.93e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APFKBCAI_00850	2.49e-183	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
APFKBCAI_00851	2.21e-191	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
APFKBCAI_00854	4.28e-253	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
APFKBCAI_00855	2.1e-285	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
APFKBCAI_00856	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
APFKBCAI_00857	1.73e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
APFKBCAI_00859	5.65e-42	-	-	-	-	-	-	-	-
APFKBCAI_00860	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APFKBCAI_00861	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APFKBCAI_00862	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APFKBCAI_00863	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
APFKBCAI_00864	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APFKBCAI_00865	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APFKBCAI_00866	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
APFKBCAI_00867	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APFKBCAI_00868	4.16e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APFKBCAI_00869	2.87e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
APFKBCAI_00870	9.42e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APFKBCAI_00871	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APFKBCAI_00872	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APFKBCAI_00873	5.06e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APFKBCAI_00874	2.12e-97	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
APFKBCAI_00875	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
APFKBCAI_00876	1.41e-130	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APFKBCAI_00877	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APFKBCAI_00878	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
APFKBCAI_00879	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
APFKBCAI_00880	3.26e-230	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
APFKBCAI_00881	7.17e-39	-	-	-	-	-	-	-	-
APFKBCAI_00882	4.58e-109	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APFKBCAI_00883	1.25e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APFKBCAI_00884	1.95e-107	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
APFKBCAI_00885	4.51e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_00886	1.03e-244	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
APFKBCAI_00887	8.84e-266	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
APFKBCAI_00888	3.23e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
APFKBCAI_00889	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_00890	2.91e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00891	7.36e-122	-	-	-	K	-	-	-	transcriptional regulator
APFKBCAI_00892	3.58e-196	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APFKBCAI_00893	1.58e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APFKBCAI_00894	1.71e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
APFKBCAI_00895	1.86e-146	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
APFKBCAI_00896	6.28e-73	-	-	-	-	-	-	-	-
APFKBCAI_00897	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APFKBCAI_00898	9.81e-142	-	-	-	S	-	-	-	Membrane
APFKBCAI_00899	4.26e-109	-	-	-	-	-	-	-	-
APFKBCAI_00900	3.11e-67	-	-	-	-	-	-	-	-
APFKBCAI_00901	1.25e-66	-	-	-	-	-	-	-	-
APFKBCAI_00902	1.95e-221	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
APFKBCAI_00903	3.24e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
APFKBCAI_00904	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
APFKBCAI_00905	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
APFKBCAI_00906	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
APFKBCAI_00907	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
APFKBCAI_00908	1.74e-226	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
APFKBCAI_00909	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
APFKBCAI_00910	6.06e-278	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
APFKBCAI_00911	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
APFKBCAI_00912	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
APFKBCAI_00913	2.4e-312	-	-	-	G	-	-	-	Major Facilitator
APFKBCAI_00914	5.44e-163	kdgR	-	-	K	-	-	-	FCD domain
APFKBCAI_00915	2.12e-243	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
APFKBCAI_00916	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
APFKBCAI_00917	2.31e-76	ps105	-	-	-	-	-	-	-
APFKBCAI_00918	2.27e-50	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
APFKBCAI_00919	1.05e-306	-	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_00921	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
APFKBCAI_00922	4.54e-138	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
APFKBCAI_00923	7.88e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
APFKBCAI_00924	7.18e-314	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
APFKBCAI_00925	6.44e-90	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
APFKBCAI_00926	1.68e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
APFKBCAI_00928	1.37e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APFKBCAI_00929	2.29e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APFKBCAI_00930	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_00931	3.03e-278	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00932	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
APFKBCAI_00933	3.48e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
APFKBCAI_00934	8.88e-132	dpsB	-	-	P	-	-	-	Belongs to the Dps family
APFKBCAI_00935	1.75e-149	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
APFKBCAI_00936	2.39e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_00937	4.84e-108	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
APFKBCAI_00939	7.21e-204	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APFKBCAI_00941	1.4e-174	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APFKBCAI_00942	3.93e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APFKBCAI_00943	1.41e-136	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
APFKBCAI_00944	1.72e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
APFKBCAI_00945	2.3e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APFKBCAI_00946	0.0	-	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_00947	3.48e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_00948	2.98e-153	-	-	-	-	-	-	-	-
APFKBCAI_00950	1.93e-137	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
APFKBCAI_00951	2.58e-178	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APFKBCAI_00952	3.2e-211	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APFKBCAI_00953	2.39e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APFKBCAI_00954	4.19e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APFKBCAI_00955	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APFKBCAI_00957	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APFKBCAI_00958	1.71e-239	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APFKBCAI_00959	3.52e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APFKBCAI_00960	1.52e-77	-	-	-	-	-	-	-	-
APFKBCAI_00961	1.52e-94	-	-	-	L	-	-	-	NUDIX domain
APFKBCAI_00962	1.55e-193	-	-	-	EG	-	-	-	EamA-like transporter family
APFKBCAI_00964	3.17e-64	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APFKBCAI_00965	2.4e-137	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
APFKBCAI_00966	5.57e-78	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
APFKBCAI_00967	3.71e-68	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
APFKBCAI_00968	4.01e-99	-	-	-	P	-	-	-	ABC-2 family transporter protein
APFKBCAI_00969	5.2e-125	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00970	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
APFKBCAI_00971	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
APFKBCAI_00972	3.57e-314	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
APFKBCAI_00973	2.06e-280	-	-	-	-	-	-	-	-
APFKBCAI_00974	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_00975	3.56e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APFKBCAI_00976	1.44e-106	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
APFKBCAI_00977	5.07e-202	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APFKBCAI_00978	9.89e-138	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
APFKBCAI_00979	9.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_00980	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_00981	2.94e-264	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
APFKBCAI_00982	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APFKBCAI_00984	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
APFKBCAI_00985	4.21e-72	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
APFKBCAI_00986	2.7e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APFKBCAI_00987	2.27e-36	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
APFKBCAI_00988	1.16e-155	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_00989	2.66e-131	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APFKBCAI_00990	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
APFKBCAI_00991	6.59e-160	-	-	-	-	-	-	-	-
APFKBCAI_00992	7.81e-33	-	-	-	-	-	-	-	-
APFKBCAI_00995	6.56e-132	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
APFKBCAI_00996	8.13e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
APFKBCAI_00997	3.07e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
APFKBCAI_00999	4.61e-57	-	-	-	-	-	-	-	-
APFKBCAI_01000	1.15e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
APFKBCAI_01001	1.56e-55	-	-	-	-	-	-	-	-
APFKBCAI_01002	7.43e-144	-	-	-	-	-	-	-	-
APFKBCAI_01003	4.21e-289	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APFKBCAI_01004	2.25e-111	-	-	-	-	-	-	-	-
APFKBCAI_01005	2.8e-255	yclK	-	-	T	-	-	-	Histidine kinase
APFKBCAI_01006	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
APFKBCAI_01007	3.5e-117	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
APFKBCAI_01008	1.36e-244	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APFKBCAI_01009	1.31e-54	-	-	-	-	-	-	-	-
APFKBCAI_01010	7.9e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
APFKBCAI_01011	4.69e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
APFKBCAI_01012	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
APFKBCAI_01013	5.94e-71	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
APFKBCAI_01015	3.99e-176	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_01016	6.05e-225	-	-	-	P	ko:K15551	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
APFKBCAI_01017	3.27e-183	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APFKBCAI_01018	0.0	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
APFKBCAI_01019	0.0	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
APFKBCAI_01020	4.32e-144	-	-	-	K	-	-	-	LysR substrate binding domain
APFKBCAI_01021	4.04e-140	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
APFKBCAI_01023	2.99e-140	-	-	-	-	-	-	-	-
APFKBCAI_01024	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APFKBCAI_01025	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_01026	1.97e-106	-	-	-	K	-	-	-	MerR HTH family regulatory protein
APFKBCAI_01027	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APFKBCAI_01028	1.3e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
APFKBCAI_01029	2.12e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
APFKBCAI_01030	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
APFKBCAI_01031	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
APFKBCAI_01032	3.27e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
APFKBCAI_01033	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
APFKBCAI_01034	9.98e-182	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APFKBCAI_01035	6.85e-122	-	-	-	F	-	-	-	NUDIX domain
APFKBCAI_01037	3.41e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
APFKBCAI_01038	1.49e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
APFKBCAI_01039	1.33e-281	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APFKBCAI_01040	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
APFKBCAI_01041	1.81e-309	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
APFKBCAI_01042	1.22e-272	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
APFKBCAI_01043	1.15e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
APFKBCAI_01044	3.46e-136	-	-	-	S	-	-	-	CYTH
APFKBCAI_01045	4.15e-160	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
APFKBCAI_01046	2.24e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APFKBCAI_01047	2.03e-218	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APFKBCAI_01048	1.14e-257	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APFKBCAI_01049	2.92e-142	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
APFKBCAI_01050	2.29e-185	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APFKBCAI_01051	4.44e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
APFKBCAI_01052	7.55e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
APFKBCAI_01053	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APFKBCAI_01054	9.97e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APFKBCAI_01055	5.57e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
APFKBCAI_01056	2.32e-198	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
APFKBCAI_01057	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APFKBCAI_01058	8.84e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
APFKBCAI_01059	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
APFKBCAI_01060	1.74e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
APFKBCAI_01061	3.94e-309	ymfH	-	-	S	-	-	-	Peptidase M16
APFKBCAI_01062	1.22e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
APFKBCAI_01063	4.37e-165	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
APFKBCAI_01064	2.26e-134	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APFKBCAI_01065	4.78e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
APFKBCAI_01066	1.41e-241	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APFKBCAI_01067	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
APFKBCAI_01068	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APFKBCAI_01069	1.71e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APFKBCAI_01070	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APFKBCAI_01071	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
APFKBCAI_01072	2.27e-306	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APFKBCAI_01073	3.52e-106	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
APFKBCAI_01074	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
APFKBCAI_01075	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
APFKBCAI_01076	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
APFKBCAI_01077	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APFKBCAI_01078	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APFKBCAI_01079	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
APFKBCAI_01080	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
APFKBCAI_01081	6.37e-125	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
APFKBCAI_01082	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
APFKBCAI_01083	3.35e-148	-	-	-	S	-	-	-	Flavodoxin-like fold
APFKBCAI_01084	7.74e-154	-	-	-	S	-	-	-	(CBS) domain
APFKBCAI_01085	2.31e-165	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
APFKBCAI_01086	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
APFKBCAI_01087	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
APFKBCAI_01088	3.27e-112	queT	-	-	S	-	-	-	QueT transporter
APFKBCAI_01089	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
APFKBCAI_01090	5.46e-51	-	-	-	-	-	-	-	-
APFKBCAI_01091	5.02e-277	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APFKBCAI_01092	2.25e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APFKBCAI_01093	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APFKBCAI_01094	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APFKBCAI_01095	7.21e-189	-	-	-	-	-	-	-	-
APFKBCAI_01096	3.88e-159	-	-	-	S	-	-	-	Tetratricopeptide repeat
APFKBCAI_01097	1.83e-158	-	-	-	-	-	-	-	-
APFKBCAI_01098	3.27e-96	-	-	-	-	-	-	-	-
APFKBCAI_01099	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
APFKBCAI_01100	2.72e-299	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APFKBCAI_01101	5.06e-236	-	-	-	K	-	-	-	Helix-turn-helix domain
APFKBCAI_01102	2.1e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APFKBCAI_01103	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_01104	6.65e-145	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
APFKBCAI_01105	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
APFKBCAI_01106	1.4e-207	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_01107	5e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
APFKBCAI_01108	9.28e-110	ORF00048	-	-	-	-	-	-	-
APFKBCAI_01109	1.32e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
APFKBCAI_01110	3.69e-135	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
APFKBCAI_01111	8.17e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_01112	9.05e-127	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
APFKBCAI_01113	1.04e-54	-	-	-	-	-	-	-	-
APFKBCAI_01114	2.88e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
APFKBCAI_01115	7.81e-67	-	-	-	-	-	-	-	-
APFKBCAI_01116	7.15e-58	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
APFKBCAI_01117	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
APFKBCAI_01118	4.63e-07	-	-	-	-	-	-	-	-
APFKBCAI_01119	2.31e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
APFKBCAI_01120	1.9e-62	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
APFKBCAI_01121	7.15e-199	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
APFKBCAI_01122	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
APFKBCAI_01123	4.83e-131	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
APFKBCAI_01124	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
APFKBCAI_01125	6.87e-162	citR	-	-	K	-	-	-	FCD
APFKBCAI_01126	4.37e-206	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
APFKBCAI_01127	1.37e-90	-	-	-	-	-	-	-	-
APFKBCAI_01128	8.21e-85	-	-	-	-	-	-	-	-
APFKBCAI_01129	8.47e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APFKBCAI_01130	1.11e-203	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APFKBCAI_01131	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APFKBCAI_01132	8.57e-134	-	-	-	-	-	-	-	-
APFKBCAI_01133	2.24e-239	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
APFKBCAI_01134	2.79e-124	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APFKBCAI_01135	1.96e-126	-	-	-	-	-	-	-	-
APFKBCAI_01136	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
APFKBCAI_01137	1.97e-168	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
APFKBCAI_01139	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
APFKBCAI_01140	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_01141	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_01142	1.03e-282	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APFKBCAI_01143	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APFKBCAI_01144	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APFKBCAI_01145	4.3e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
APFKBCAI_01146	4.11e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APFKBCAI_01147	2.1e-246	-	-	-	-	-	-	-	-
APFKBCAI_01148	5.93e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_01149	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
APFKBCAI_01150	7.76e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APFKBCAI_01151	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
APFKBCAI_01152	1.98e-65	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_01153	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APFKBCAI_01154	1.06e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
APFKBCAI_01155	5.42e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
APFKBCAI_01156	4.07e-135	-	-	-	-	-	-	-	-
APFKBCAI_01157	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
APFKBCAI_01158	8.71e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
APFKBCAI_01159	9.48e-186	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
APFKBCAI_01160	9.39e-196	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APFKBCAI_01161	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
APFKBCAI_01162	2.77e-224	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
APFKBCAI_01163	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
APFKBCAI_01164	3.17e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APFKBCAI_01165	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
APFKBCAI_01166	8.21e-91	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APFKBCAI_01167	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APFKBCAI_01168	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APFKBCAI_01169	2.44e-111	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APFKBCAI_01170	5.69e-65	-	-	-	-	-	-	-	-
APFKBCAI_01171	8.19e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
APFKBCAI_01172	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APFKBCAI_01173	2.83e-90	-	-	-	-	-	-	-	-
APFKBCAI_01174	1e-219	ccpB	-	-	K	-	-	-	lacI family
APFKBCAI_01175	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
APFKBCAI_01176	5.88e-202	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APFKBCAI_01177	3.91e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APFKBCAI_01178	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APFKBCAI_01179	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
APFKBCAI_01180	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
APFKBCAI_01181	1.94e-104	-	-	-	S	-	-	-	NusG domain II
APFKBCAI_01182	7.23e-128	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
APFKBCAI_01183	2.7e-231	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APFKBCAI_01184	2.93e-42	-	-	-	-	-	-	-	-
APFKBCAI_01185	3.29e-50	-	-	-	-	-	-	-	-
APFKBCAI_01187	1.39e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_01188	6.32e-277	-	-	-	-	-	-	-	-
APFKBCAI_01189	1.04e-249	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
APFKBCAI_01190	3.82e-157	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
APFKBCAI_01191	6.29e-250	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
APFKBCAI_01192	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
APFKBCAI_01193	1.06e-184	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APFKBCAI_01194	2.79e-97	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APFKBCAI_01195	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
APFKBCAI_01196	3.44e-185	-	-	-	K	-	-	-	sequence-specific DNA binding
APFKBCAI_01197	2.03e-71	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
APFKBCAI_01198	1.01e-231	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
APFKBCAI_01199	1.22e-125	-	-	-	-	-	-	-	-
APFKBCAI_01201	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APFKBCAI_01202	4.24e-183	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
APFKBCAI_01203	3.93e-226	-	-	-	S	-	-	-	Membrane
APFKBCAI_01204	3.54e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
APFKBCAI_01205	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APFKBCAI_01206	2.42e-298	inlJ	-	-	M	-	-	-	MucBP domain
APFKBCAI_01207	6.42e-88	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APFKBCAI_01208	9.79e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_01209	1.12e-138	-	-	-	K	-	-	-	sequence-specific DNA binding
APFKBCAI_01210	1.06e-258	yacL	-	-	S	-	-	-	domain protein
APFKBCAI_01211	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APFKBCAI_01212	2.6e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
APFKBCAI_01213	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APFKBCAI_01214	2.64e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APFKBCAI_01215	5.09e-148	-	-	-	J	-	-	-	HAD-hyrolase-like
APFKBCAI_01216	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
APFKBCAI_01217	4.23e-104	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
APFKBCAI_01218	4.24e-307	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
APFKBCAI_01219	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APFKBCAI_01220	8.53e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
APFKBCAI_01221	7.61e-217	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APFKBCAI_01222	1.54e-215	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APFKBCAI_01223	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APFKBCAI_01224	8.04e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
APFKBCAI_01225	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
APFKBCAI_01226	1.14e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
APFKBCAI_01227	5.95e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APFKBCAI_01228	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
APFKBCAI_01229	8.35e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APFKBCAI_01230	2.36e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APFKBCAI_01231	8.57e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
APFKBCAI_01232	2.56e-70	-	-	-	-	-	-	-	-
APFKBCAI_01233	5.18e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_01235	4.68e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
APFKBCAI_01236	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
APFKBCAI_01237	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
APFKBCAI_01238	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APFKBCAI_01239	4.92e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APFKBCAI_01240	1.49e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
APFKBCAI_01241	1.57e-188	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APFKBCAI_01242	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APFKBCAI_01243	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
APFKBCAI_01244	2.61e-98	-	-	-	L	-	-	-	Resolvase, N-terminal
APFKBCAI_01245	1.17e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
APFKBCAI_01246	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APFKBCAI_01247	4.46e-181	yceF	-	-	P	ko:K05794	-	ko00000	membrane
APFKBCAI_01248	7.74e-203	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APFKBCAI_01249	5.81e-221	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
APFKBCAI_01250	5.95e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
APFKBCAI_01252	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APFKBCAI_01253	5.93e-128	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APFKBCAI_01254	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
APFKBCAI_01255	3.88e-264	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APFKBCAI_01256	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APFKBCAI_01257	4.01e-44	-	-	-	-	-	-	-	-
APFKBCAI_01258	4.13e-109	-	-	-	S	-	-	-	ASCH
APFKBCAI_01259	2.01e-81	-	-	-	-	-	-	-	-
APFKBCAI_01260	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
APFKBCAI_01261	4.87e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APFKBCAI_01262	2.18e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APFKBCAI_01263	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
APFKBCAI_01264	8.69e-186	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
APFKBCAI_01265	9.96e-244	-	-	-	-	-	-	-	-
APFKBCAI_01270	3.44e-162	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
APFKBCAI_01271	8.4e-259	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APFKBCAI_01272	1.45e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
APFKBCAI_01273	7.51e-145	-	-	-	-	-	-	-	-
APFKBCAI_01274	2.34e-92	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
APFKBCAI_01275	3.05e-72	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
APFKBCAI_01276	2.31e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_01277	1.72e-208	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_01278	3.47e-105	-	-	-	IQ	-	-	-	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APFKBCAI_01279	2.71e-122	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
APFKBCAI_01280	4.06e-35	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
APFKBCAI_01281	1.95e-47	-	-	-	-	-	-	-	-
APFKBCAI_01282	1.3e-71	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
APFKBCAI_01283	2.15e-99	yphH	-	-	S	-	-	-	Cupin domain
APFKBCAI_01284	1.11e-203	-	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_01285	1.03e-164	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APFKBCAI_01286	7.56e-214	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APFKBCAI_01287	1.9e-52	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APFKBCAI_01288	1.69e-87	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APFKBCAI_01289	1.15e-204	-	-	-	T	-	-	-	GHKL domain
APFKBCAI_01290	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APFKBCAI_01291	4.72e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
APFKBCAI_01292	1.14e-170	-	-	-	F	-	-	-	deoxynucleoside kinase
APFKBCAI_01293	1.19e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
APFKBCAI_01294	3.75e-215	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
APFKBCAI_01295	4.68e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APFKBCAI_01296	1.88e-154	-	-	-	G	-	-	-	Phosphoglycerate mutase family
APFKBCAI_01297	4.1e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
APFKBCAI_01298	2.93e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
APFKBCAI_01299	4.72e-141	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
APFKBCAI_01300	3.84e-94	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
APFKBCAI_01301	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
APFKBCAI_01302	7.51e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
APFKBCAI_01303	0.000138	-	-	-	-	-	-	-	-
APFKBCAI_01304	1.54e-247	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APFKBCAI_01305	3.56e-209	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
APFKBCAI_01306	1.26e-217	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
APFKBCAI_01307	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
APFKBCAI_01308	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APFKBCAI_01309	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
APFKBCAI_01310	7.82e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APFKBCAI_01311	6.51e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
APFKBCAI_01312	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
APFKBCAI_01313	2.89e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
APFKBCAI_01314	4.97e-114	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
APFKBCAI_01315	6.59e-118	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
APFKBCAI_01316	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
APFKBCAI_01317	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
APFKBCAI_01318	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APFKBCAI_01319	1.33e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APFKBCAI_01320	2.79e-125	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_01321	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
APFKBCAI_01322	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APFKBCAI_01323	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APFKBCAI_01324	1.34e-36	-	-	-	-	-	-	-	-
APFKBCAI_01325	7.37e-169	-	-	-	-	-	-	-	-
APFKBCAI_01326	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APFKBCAI_01327	2.54e-30	-	-	-	S	-	-	-	Short C-terminal domain
APFKBCAI_01328	2.2e-272	yqiG	-	-	C	-	-	-	Oxidoreductase
APFKBCAI_01329	1.49e-167	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
APFKBCAI_01330	7.17e-232	ydhF	-	-	S	-	-	-	Aldo keto reductase
APFKBCAI_01331	4.57e-71	-	-	-	S	-	-	-	Enterocin A Immunity
APFKBCAI_01332	1.05e-70	-	-	-	-	-	-	-	-
APFKBCAI_01333	1.3e-314	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
APFKBCAI_01334	8.21e-92	-	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_01335	2.25e-174	-	-	-	S	-	-	-	CAAX protease self-immunity
APFKBCAI_01339	6.51e-30	-	-	-	-	-	-	-	-
APFKBCAI_01340	2.63e-59	-	-	-	S	-	-	-	Enterocin A Immunity
APFKBCAI_01343	4.33e-168	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
APFKBCAI_01344	1.5e-103	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
APFKBCAI_01346	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
APFKBCAI_01347	7.14e-297	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
APFKBCAI_01348	1.15e-75	-	-	-	-	-	-	-	-
APFKBCAI_01349	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
APFKBCAI_01351	5.24e-113	-	-	-	-	-	-	-	-
APFKBCAI_01352	1.95e-118	-	-	-	S	-	-	-	MucBP domain
APFKBCAI_01353	2.62e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
APFKBCAI_01356	2.03e-106	-	-	-	E	-	-	-	AAA domain
APFKBCAI_01357	2.11e-171	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
APFKBCAI_01358	2.5e-106	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
APFKBCAI_01359	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
APFKBCAI_01360	3.18e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
APFKBCAI_01361	1.44e-94	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
APFKBCAI_01362	7.58e-289	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
APFKBCAI_01363	3.89e-75	-	-	-	-	-	-	-	-
APFKBCAI_01364	1.12e-293	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APFKBCAI_01365	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
APFKBCAI_01366	8.48e-23	-	-	-	S	-	-	-	function, without similarity to other proteins
APFKBCAI_01367	2.43e-87	-	-	-	-	-	-	-	-
APFKBCAI_01368	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_01369	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
APFKBCAI_01370	9.12e-199	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APFKBCAI_01372	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_01373	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
APFKBCAI_01374	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
APFKBCAI_01375	5.58e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APFKBCAI_01376	2.49e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APFKBCAI_01377	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
APFKBCAI_01378	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APFKBCAI_01379	3.74e-284	-	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_01380	4.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APFKBCAI_01381	1.18e-274	-	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_01382	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
APFKBCAI_01383	1.6e-93	-	-	-	-	-	-	-	-
APFKBCAI_01384	3.78e-225	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_01385	1.77e-175	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
APFKBCAI_01386	1.59e-165	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_01387	1.78e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
APFKBCAI_01388	1.63e-104	-	-	-	K	-	-	-	FR47-like protein
APFKBCAI_01390	6.88e-129	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
APFKBCAI_01391	6.51e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
APFKBCAI_01392	1.03e-204	-	-	-	G	-	-	-	Aldose 1-epimerase
APFKBCAI_01393	1.49e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
APFKBCAI_01394	1.41e-206	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
APFKBCAI_01395	1.71e-64	-	-	-	-	-	-	-	-
APFKBCAI_01396	9.92e-266	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
APFKBCAI_01397	1.64e-269	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
APFKBCAI_01398	1.76e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
APFKBCAI_01399	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
APFKBCAI_01400	3.38e-104	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
APFKBCAI_01401	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APFKBCAI_01402	6.41e-84	-	-	-	-	-	-	-	-
APFKBCAI_01403	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_01404	4.78e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
APFKBCAI_01405	4.26e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
APFKBCAI_01406	1.16e-124	-	-	-	-	-	-	-	-
APFKBCAI_01407	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_01408	4.36e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
APFKBCAI_01409	1.88e-307	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
APFKBCAI_01410	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APFKBCAI_01411	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
APFKBCAI_01412	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
APFKBCAI_01413	6.69e-39	-	-	-	-	-	-	-	-
APFKBCAI_01414	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
APFKBCAI_01415	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APFKBCAI_01416	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APFKBCAI_01417	9.11e-134	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
APFKBCAI_01418	6.02e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APFKBCAI_01419	1.74e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APFKBCAI_01420	1.9e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
APFKBCAI_01421	5.52e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APFKBCAI_01422	3.56e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APFKBCAI_01423	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APFKBCAI_01424	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APFKBCAI_01425	1.07e-238	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
APFKBCAI_01426	2.36e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APFKBCAI_01427	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
APFKBCAI_01428	2.93e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
APFKBCAI_01429	9.59e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
APFKBCAI_01430	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
APFKBCAI_01431	1.09e-139	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APFKBCAI_01432	2.53e-264	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
APFKBCAI_01433	3.07e-156	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
APFKBCAI_01434	5.63e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_01435	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
APFKBCAI_01436	9.97e-119	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
APFKBCAI_01437	1.34e-175	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
APFKBCAI_01438	1.9e-72	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APFKBCAI_01439	9.38e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
APFKBCAI_01440	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
APFKBCAI_01441	7.68e-225	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
APFKBCAI_01442	5.54e-30	-	-	-	-	-	-	-	-
APFKBCAI_01443	1.97e-88	-	-	-	-	-	-	-	-
APFKBCAI_01445	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
APFKBCAI_01446	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APFKBCAI_01447	4.88e-199	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
APFKBCAI_01448	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
APFKBCAI_01449	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
APFKBCAI_01450	1.25e-233	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
APFKBCAI_01451	2.5e-203	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APFKBCAI_01452	2.79e-77	-	-	-	S	-	-	-	YtxH-like protein
APFKBCAI_01453	1.14e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
APFKBCAI_01454	2.48e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_01455	4.39e-286	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_01456	3.86e-190	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
APFKBCAI_01457	1.11e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APFKBCAI_01459	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
APFKBCAI_01460	5.69e-147	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APFKBCAI_01462	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
APFKBCAI_01463	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_01464	0.0	-	-	-	N	-	-	-	domain, Protein
APFKBCAI_01465	2.56e-177	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APFKBCAI_01467	8.57e-248	-	-	-	S	-	-	-	Cell surface protein
APFKBCAI_01468	1.65e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
APFKBCAI_01469	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APFKBCAI_01470	1.52e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APFKBCAI_01471	1.15e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APFKBCAI_01472	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APFKBCAI_01473	1.86e-316	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
APFKBCAI_01474	1.12e-216	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
APFKBCAI_01475	2.33e-283	-	-	-	V	ko:K07454	-	ko00000	regulation of methylation-dependent chromatin silencing
APFKBCAI_01476	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APFKBCAI_01477	1.18e-85	-	-	-	-	-	-	-	-
APFKBCAI_01478	1.24e-164	-	-	-	S	-	-	-	SseB protein N-terminal domain
APFKBCAI_01479	2.81e-174	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
APFKBCAI_01480	2.07e-296	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
APFKBCAI_01481	1.13e-93	-	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_01482	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APFKBCAI_01483	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
APFKBCAI_01484	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APFKBCAI_01485	4.79e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
APFKBCAI_01486	4.62e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
APFKBCAI_01487	8.79e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
APFKBCAI_01488	7.56e-238	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APFKBCAI_01489	4.16e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
APFKBCAI_01490	1.14e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
APFKBCAI_01491	6.56e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
APFKBCAI_01492	1.19e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APFKBCAI_01493	9.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
APFKBCAI_01494	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APFKBCAI_01495	8.06e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
APFKBCAI_01496	2.27e-268	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
APFKBCAI_01497	3.4e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
APFKBCAI_01498	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APFKBCAI_01499	1.01e-157	csrR	-	-	K	-	-	-	response regulator
APFKBCAI_01500	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APFKBCAI_01501	9.37e-230	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APFKBCAI_01502	1.45e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
APFKBCAI_01503	2.48e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APFKBCAI_01504	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
APFKBCAI_01505	1.44e-90	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
APFKBCAI_01506	4.32e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APFKBCAI_01507	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APFKBCAI_01508	1.59e-266	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APFKBCAI_01509	9.83e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
APFKBCAI_01510	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APFKBCAI_01512	3.99e-167	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
APFKBCAI_01513	1.72e-46	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APFKBCAI_01514	6.79e-155	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APFKBCAI_01515	3.39e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
APFKBCAI_01516	1.91e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
APFKBCAI_01517	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
APFKBCAI_01518	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
APFKBCAI_01519	2.21e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
APFKBCAI_01520	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
APFKBCAI_01521	4.82e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
APFKBCAI_01522	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
APFKBCAI_01523	2.75e-34	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
APFKBCAI_01524	1.97e-230	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APFKBCAI_01525	1.42e-306	ynbB	-	-	P	-	-	-	aluminum resistance
APFKBCAI_01526	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
APFKBCAI_01527	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
APFKBCAI_01528	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
APFKBCAI_01529	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
APFKBCAI_01530	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APFKBCAI_01532	2.31e-298	-	-	-	S	-	-	-	Membrane
APFKBCAI_01533	1.77e-20	-	-	-	-	-	-	-	-
APFKBCAI_01534	1.88e-43	-	-	-	-	-	-	-	-
APFKBCAI_01535	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
APFKBCAI_01536	1.7e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
APFKBCAI_01537	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
APFKBCAI_01538	2.92e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APFKBCAI_01539	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APFKBCAI_01540	8.72e-100	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
APFKBCAI_01541	1.29e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APFKBCAI_01542	9.8e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APFKBCAI_01543	6.35e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APFKBCAI_01544	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APFKBCAI_01545	2.76e-187	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APFKBCAI_01546	4.68e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
APFKBCAI_01547	1.03e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
APFKBCAI_01548	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
APFKBCAI_01549	8.07e-68	-	-	-	-	-	-	-	-
APFKBCAI_01550	1.23e-153	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
APFKBCAI_01551	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
APFKBCAI_01552	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APFKBCAI_01553	3.8e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APFKBCAI_01554	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APFKBCAI_01555	1.38e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APFKBCAI_01556	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APFKBCAI_01557	2.59e-174	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
APFKBCAI_01558	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
APFKBCAI_01559	4.06e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APFKBCAI_01560	2.81e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
APFKBCAI_01561	2.42e-162	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
APFKBCAI_01562	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
APFKBCAI_01563	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
APFKBCAI_01564	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
APFKBCAI_01565	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APFKBCAI_01566	1.41e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APFKBCAI_01567	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APFKBCAI_01568	1.17e-244	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APFKBCAI_01569	1.97e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APFKBCAI_01570	8.93e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_01571	6.51e-196	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APFKBCAI_01572	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
APFKBCAI_01573	2.68e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APFKBCAI_01574	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
APFKBCAI_01575	3.16e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APFKBCAI_01576	1.12e-69	-	-	-	-	-	-	-	-
APFKBCAI_01577	2.1e-33	-	-	-	-	-	-	-	-
APFKBCAI_01578	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APFKBCAI_01579	1.02e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APFKBCAI_01580	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
APFKBCAI_01581	6.31e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
APFKBCAI_01582	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APFKBCAI_01583	1.45e-187	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
APFKBCAI_01584	4.71e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APFKBCAI_01585	1.08e-35	-	-	-	-	-	-	-	-
APFKBCAI_01586	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
APFKBCAI_01587	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
APFKBCAI_01588	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_01589	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_01590	3.12e-177	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
APFKBCAI_01591	1.2e-302	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
APFKBCAI_01592	4.02e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
APFKBCAI_01593	6.09e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
APFKBCAI_01594	1.29e-63	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
APFKBCAI_01595	9.72e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
APFKBCAI_01596	3.28e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APFKBCAI_01597	9.72e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
APFKBCAI_01598	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APFKBCAI_01599	2.05e-177	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APFKBCAI_01600	4.82e-182	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
APFKBCAI_01601	2.89e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
APFKBCAI_01602	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APFKBCAI_01603	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APFKBCAI_01604	4.69e-91	-	-	-	-	-	-	-	-
APFKBCAI_01605	0.0	-	-	-	-	-	-	-	-
APFKBCAI_01607	0.0	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
APFKBCAI_01609	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
APFKBCAI_01610	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APFKBCAI_01611	1.3e-238	mocA	-	-	S	-	-	-	Oxidoreductase
APFKBCAI_01612	7.04e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_01613	1.08e-143	-	-	-	S	-	-	-	Flavodoxin-like fold
APFKBCAI_01615	8.97e-81	-	-	-	-	-	-	-	-
APFKBCAI_01616	3.45e-37	-	-	-	-	-	-	-	-
APFKBCAI_01617	7.44e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
APFKBCAI_01618	1.1e-50	-	-	-	-	-	-	-	-
APFKBCAI_01619	2.26e-143	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
APFKBCAI_01620	8.57e-114	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
APFKBCAI_01621	8.28e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
APFKBCAI_01622	1.17e-163	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APFKBCAI_01623	1.7e-70	-	-	-	-	-	-	-	-
APFKBCAI_01624	2.56e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
APFKBCAI_01625	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APFKBCAI_01626	1.15e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
APFKBCAI_01627	9.93e-229	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APFKBCAI_01628	2.65e-223	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APFKBCAI_01629	3.35e-66	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APFKBCAI_01630	1.38e-100	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APFKBCAI_01631	8.97e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
APFKBCAI_01632	0.0	ybeC	-	-	E	-	-	-	amino acid
APFKBCAI_01633	2.21e-121	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
APFKBCAI_01658	1.05e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
APFKBCAI_01659	4.01e-80	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
APFKBCAI_01660	5.06e-181	-	-	-	-	-	-	-	-
APFKBCAI_01661	3.79e-223	-	-	-	-	-	-	-	-
APFKBCAI_01662	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
APFKBCAI_01664	3.44e-239	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APFKBCAI_01665	5.2e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
APFKBCAI_01666	3.59e-213	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
APFKBCAI_01668	1.03e-281	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
APFKBCAI_01669	2.31e-115	-	-	-	-	-	-	-	-
APFKBCAI_01670	1.51e-195	-	-	-	K	-	-	-	acetyltransferase
APFKBCAI_01671	1.04e-287	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
APFKBCAI_01673	5.28e-283	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APFKBCAI_01674	6.64e-80	hol	-	-	S	-	-	-	Bacteriophage holin
APFKBCAI_01675	4.74e-70	-	-	-	-	-	-	-	-
APFKBCAI_01677	6.88e-71	-	-	-	-	-	-	-	-
APFKBCAI_01678	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
APFKBCAI_01679	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
APFKBCAI_01680	4.49e-278	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
APFKBCAI_01681	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
APFKBCAI_01682	1.85e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
APFKBCAI_01683	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APFKBCAI_01684	2.8e-277	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APFKBCAI_01685	7.1e-78	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
APFKBCAI_01686	9.18e-60	-	-	-	-	-	-	-	-
APFKBCAI_01688	1.9e-315	-	-	-	S	-	-	-	cellulase activity
APFKBCAI_01689	1.45e-46	-	-	-	-	-	-	-	-
APFKBCAI_01690	2.02e-83	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
APFKBCAI_01691	1.8e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APFKBCAI_01692	2.61e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
APFKBCAI_01693	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
APFKBCAI_01694	3.54e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
APFKBCAI_01695	5.08e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
APFKBCAI_01696	4.68e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APFKBCAI_01697	5.98e-144	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
APFKBCAI_01698	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
APFKBCAI_01699	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APFKBCAI_01700	6.9e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
APFKBCAI_01701	8.09e-239	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
APFKBCAI_01702	3.48e-73	-	-	-	-	-	-	-	-
APFKBCAI_01703	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
APFKBCAI_01704	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
APFKBCAI_01705	3.4e-173	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APFKBCAI_01706	3.04e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
APFKBCAI_01707	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
APFKBCAI_01708	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
APFKBCAI_01709	5.39e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
APFKBCAI_01710	4.48e-120	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
APFKBCAI_01711	4.56e-110	ytxH	-	-	S	-	-	-	YtxH-like protein
APFKBCAI_01712	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APFKBCAI_01713	2.14e-201	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
APFKBCAI_01714	2.4e-201	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
APFKBCAI_01715	5.39e-111	ykuL	-	-	S	-	-	-	CBS domain
APFKBCAI_01716	7.42e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
APFKBCAI_01717	9.11e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
APFKBCAI_01718	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
APFKBCAI_01719	1.61e-107	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
APFKBCAI_01720	5.21e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APFKBCAI_01721	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APFKBCAI_01722	1.2e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
APFKBCAI_01723	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APFKBCAI_01724	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
APFKBCAI_01725	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APFKBCAI_01726	3.15e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
APFKBCAI_01727	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APFKBCAI_01728	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
APFKBCAI_01729	1.32e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APFKBCAI_01730	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
APFKBCAI_01731	3.9e-264	-	-	-	-	-	-	-	-
APFKBCAI_01732	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APFKBCAI_01733	1.17e-218	-	-	-	-	-	-	-	-
APFKBCAI_01734	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APFKBCAI_01735	7.98e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
APFKBCAI_01736	6.26e-305	ytoI	-	-	K	-	-	-	DRTGG domain
APFKBCAI_01737	2.17e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APFKBCAI_01738	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APFKBCAI_01739	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
APFKBCAI_01740	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
APFKBCAI_01741	1.66e-77	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
APFKBCAI_01742	1.64e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APFKBCAI_01743	2.16e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APFKBCAI_01744	1.43e-249	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APFKBCAI_01745	6.95e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APFKBCAI_01746	1.25e-134	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
APFKBCAI_01747	1.19e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APFKBCAI_01748	6.91e-283	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
APFKBCAI_01749	5.25e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
APFKBCAI_01750	5.25e-149	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
APFKBCAI_01751	1.26e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
APFKBCAI_01752	6.15e-160	-	-	-	-	-	-	-	-
APFKBCAI_01753	1.3e-201	dkgB	-	-	S	-	-	-	reductase
APFKBCAI_01754	6.13e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
APFKBCAI_01755	5.66e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
APFKBCAI_01756	3.72e-100	-	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_01757	3.04e-154	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
APFKBCAI_01758	2.29e-255	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APFKBCAI_01759	2.39e-120	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APFKBCAI_01760	1.03e-77	-	-	-	-	-	-	-	-
APFKBCAI_01761	6.84e-225	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APFKBCAI_01762	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
APFKBCAI_01763	1.91e-78	-	-	-	-	-	-	-	-
APFKBCAI_01764	1.17e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
APFKBCAI_01765	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
APFKBCAI_01766	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APFKBCAI_01767	4.96e-222	-	-	-	K	-	-	-	sequence-specific DNA binding
APFKBCAI_01768	2.95e-123	-	-	-	-	-	-	-	-
APFKBCAI_01769	1.6e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APFKBCAI_01770	8.81e-218	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
APFKBCAI_01771	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
APFKBCAI_01772	1.4e-205	mleR	-	-	K	-	-	-	LysR family
APFKBCAI_01773	1.22e-220	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
APFKBCAI_01774	2.41e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
APFKBCAI_01775	5.82e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APFKBCAI_01776	4.22e-170	-	-	-	-	-	-	-	-
APFKBCAI_01777	5.47e-137	-	-	-	S	-	-	-	Flavin reductase like domain
APFKBCAI_01778	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
APFKBCAI_01779	7.08e-96	-	-	-	-	-	-	-	-
APFKBCAI_01780	2.46e-130	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APFKBCAI_01781	1.99e-36	-	-	-	-	-	-	-	-
APFKBCAI_01782	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
APFKBCAI_01783	6.82e-104	-	-	-	-	-	-	-	-
APFKBCAI_01784	2.38e-74	-	-	-	-	-	-	-	-
APFKBCAI_01785	2.06e-234	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
APFKBCAI_01786	1.46e-65	-	-	-	-	-	-	-	-
APFKBCAI_01787	5.89e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
APFKBCAI_01788	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
APFKBCAI_01789	1.18e-230	-	-	-	K	-	-	-	sequence-specific DNA binding
APFKBCAI_01792	3.57e-260	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
APFKBCAI_01793	1.19e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
APFKBCAI_01794	1.99e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
APFKBCAI_01795	1.87e-307	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
APFKBCAI_01796	4.31e-165	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
APFKBCAI_01797	3.08e-93	-	-	-	S	-	-	-	GtrA-like protein
APFKBCAI_01798	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
APFKBCAI_01799	1.9e-231	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
APFKBCAI_01800	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
APFKBCAI_01801	1.08e-218	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
APFKBCAI_01802	4.78e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_01803	2.78e-207	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
APFKBCAI_01804	8.37e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_01805	4.54e-215	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
APFKBCAI_01806	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
APFKBCAI_01807	1.83e-150	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
APFKBCAI_01809	8.01e-254	-	-	-	-	-	-	-	-
APFKBCAI_01810	1.35e-196	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
APFKBCAI_01811	7.75e-115	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
APFKBCAI_01813	1.22e-155	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
APFKBCAI_01814	6.41e-192	-	-	-	I	-	-	-	alpha/beta hydrolase fold
APFKBCAI_01815	5.02e-268	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
APFKBCAI_01816	5.22e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
APFKBCAI_01817	4.79e-21	-	-	-	-	-	-	-	-
APFKBCAI_01818	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
APFKBCAI_01819	3.21e-266	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APFKBCAI_01820	1.07e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
APFKBCAI_01821	2.49e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
APFKBCAI_01822	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
APFKBCAI_01823	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
APFKBCAI_01824	1.64e-236	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
APFKBCAI_01825	1.69e-207	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
APFKBCAI_01826	6.47e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
APFKBCAI_01827	3.74e-198	-	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_01828	4.95e-124	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
APFKBCAI_01829	5.34e-78	-	-	-	-	-	-	-	-
APFKBCAI_01830	1.32e-86	-	-	-	G	-	-	-	PTS system fructose IIA component
APFKBCAI_01831	3.46e-171	-	-	-	G	-	-	-	PTS system mannose/fructose/sorbose family IID component
APFKBCAI_01832	2.22e-160	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APFKBCAI_01833	5.34e-108	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
APFKBCAI_01835	2.01e-12	-	-	-	-	-	-	-	-
APFKBCAI_01836	2.28e-249	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
APFKBCAI_01837	5.62e-211	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
APFKBCAI_01838	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
APFKBCAI_01839	1.36e-203	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
APFKBCAI_01840	1.64e-32	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
APFKBCAI_01841	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APFKBCAI_01843	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APFKBCAI_01844	1.81e-309	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APFKBCAI_01845	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
APFKBCAI_01846	5.46e-178	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
APFKBCAI_01848	2.8e-171	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
APFKBCAI_01849	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APFKBCAI_01850	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
APFKBCAI_01851	2.82e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
APFKBCAI_01852	2.56e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
APFKBCAI_01853	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
APFKBCAI_01854	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
APFKBCAI_01855	2.24e-13	-	-	-	-	-	-	-	-
APFKBCAI_01857	3.56e-194	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
APFKBCAI_01858	3.15e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
APFKBCAI_01859	6.58e-226	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
APFKBCAI_01860	6.6e-312	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
APFKBCAI_01861	5.21e-200	-	-	-	C	-	-	-	nadph quinone reductase
APFKBCAI_01862	5.98e-121	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
APFKBCAI_01863	3.05e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
APFKBCAI_01864	1.4e-148	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
APFKBCAI_01865	5.17e-176	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
APFKBCAI_01866	1.34e-201	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_01867	2.67e-192	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
APFKBCAI_01868	2.14e-89	-	-	-	K	-	-	-	LytTr DNA-binding domain
APFKBCAI_01869	4.03e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
APFKBCAI_01870	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
APFKBCAI_01871	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
APFKBCAI_01872	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
APFKBCAI_01873	1.41e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
APFKBCAI_01874	9.51e-148	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
APFKBCAI_01875	1.96e-234	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
APFKBCAI_01876	4.7e-95	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
APFKBCAI_01877	6.52e-98	-	-	-	O	-	-	-	OsmC-like protein
APFKBCAI_01878	6.56e-87	-	-	-	-	-	-	-	-
APFKBCAI_01879	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
APFKBCAI_01880	1.86e-316	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
APFKBCAI_01881	3.11e-219	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
APFKBCAI_01882	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
APFKBCAI_01883	4.39e-273	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
APFKBCAI_01884	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_01885	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APFKBCAI_01886	3.66e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
APFKBCAI_01887	2.07e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
APFKBCAI_01888	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_01889	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_01890	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APFKBCAI_01891	9.2e-210	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
APFKBCAI_01892	5.86e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
APFKBCAI_01893	4.61e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
APFKBCAI_01894	0.0	-	-	-	L	-	-	-	PFAM Integrase core domain
APFKBCAI_01895	1.55e-116	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
APFKBCAI_01896	0.0	-	-	-	S	-	-	-	Phage tail protein
APFKBCAI_01897	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
APFKBCAI_01898	2.72e-27	-	-	-	-	-	-	-	-
APFKBCAI_01899	1.89e-93	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
APFKBCAI_01900	3.25e-39	-	-	-	-	-	-	-	-
APFKBCAI_01901	8.05e-88	-	-	-	S	-	-	-	exonuclease activity
APFKBCAI_01902	6.82e-53	-	-	-	S	-	-	-	Phage head-tail joining protein
APFKBCAI_01903	4.38e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
APFKBCAI_01904	4.67e-37	-	-	-	S	-	-	-	peptidase activity
APFKBCAI_01905	2.1e-257	-	-	-	S	-	-	-	peptidase activity
APFKBCAI_01906	1.34e-139	-	-	-	S	-	-	-	peptidase activity
APFKBCAI_01907	6.69e-283	-	-	-	S	-	-	-	Phage portal protein
APFKBCAI_01909	0.0	-	-	-	S	-	-	-	Phage Terminase
APFKBCAI_01910	2.95e-101	-	-	-	S	-	-	-	Phage terminase, small subunit
APFKBCAI_01911	1.26e-91	-	-	-	S	-	-	-	HNH endonuclease
APFKBCAI_01912	2.99e-66	-	-	-	-	-	-	-	-
APFKBCAI_01913	3.24e-125	-	-	-	S	-	-	-	HNH endonuclease
APFKBCAI_01914	5.47e-301	-	-	-	-	-	-	-	-
APFKBCAI_01916	6.97e-28	-	-	-	-	-	-	-	-
APFKBCAI_01917	4.4e-101	-	-	-	-	-	-	-	-
APFKBCAI_01920	7.07e-38	-	-	-	-	-	-	-	-
APFKBCAI_01921	2.99e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
APFKBCAI_01923	1.13e-157	-	-	-	S	-	-	-	DNA methylation
APFKBCAI_01925	2.27e-86	-	-	-	S	-	-	-	magnesium ion binding
APFKBCAI_01926	2.3e-44	-	-	-	-	-	-	-	-
APFKBCAI_01928	3.35e-157	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
APFKBCAI_01929	7.16e-121	-	-	-	S	-	-	-	calcium ion binding
APFKBCAI_01930	1.33e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
APFKBCAI_01931	4.31e-167	-	-	-	S	-	-	-	AAA domain
APFKBCAI_01932	2.4e-104	-	-	-	S	-	-	-	Siphovirus Gp157
APFKBCAI_01939	2.87e-12	-	-	-	-	-	-	-	-
APFKBCAI_01940	3.46e-168	-	-	-	S	-	-	-	sequence-specific DNA binding
APFKBCAI_01941	1.4e-24	-	-	-	K	-	-	-	Peptidase S24-like
APFKBCAI_01942	1.28e-112	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
APFKBCAI_01943	1.35e-211	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APFKBCAI_01944	5.86e-84	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
APFKBCAI_01945	2.83e-267	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
APFKBCAI_01946	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
APFKBCAI_01947	2.87e-270	-	-	-	-	-	-	-	-
APFKBCAI_01948	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
APFKBCAI_01949	1.88e-86	pip	-	-	V	ko:K01421	-	ko00000	domain protein
APFKBCAI_01950	8.94e-88	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_01951	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_01952	7.51e-311	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APFKBCAI_01953	6.55e-227	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
APFKBCAI_01954	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
APFKBCAI_01956	7.51e-204	-	-	-	GM	-	-	-	NmrA-like family
APFKBCAI_01957	6.84e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
APFKBCAI_01958	1.02e-185	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
APFKBCAI_01959	6.61e-189	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APFKBCAI_01960	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
APFKBCAI_01961	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APFKBCAI_01962	9.15e-90	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APFKBCAI_01963	4.91e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APFKBCAI_01964	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
APFKBCAI_01965	3.44e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
APFKBCAI_01966	6.47e-219	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
APFKBCAI_01967	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APFKBCAI_01968	5.82e-223	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APFKBCAI_01969	4.21e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
APFKBCAI_01970	7.93e-94	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
APFKBCAI_01971	7.01e-244	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
APFKBCAI_01972	2.02e-288	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
APFKBCAI_01973	6.3e-82	-	-	-	P	-	-	-	Rhodanese-like domain
APFKBCAI_01974	9.96e-109	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APFKBCAI_01975	5.55e-101	-	-	-	T	-	-	-	diguanylate cyclase activity
APFKBCAI_01976	0.000946	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
APFKBCAI_01977	2.65e-233	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
APFKBCAI_01978	2.24e-228	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
APFKBCAI_01979	2.65e-97	-	-	-	S	-	-	-	Protein conserved in bacteria
APFKBCAI_01980	4.47e-79	-	-	-	-	-	-	-	-
APFKBCAI_01981	9.3e-100	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
APFKBCAI_01982	2.7e-67	-	-	-	T	-	-	-	diguanylate cyclase
APFKBCAI_01983	1.12e-213	nox	-	-	C	-	-	-	NADH oxidase
APFKBCAI_01984	2.87e-92	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
APFKBCAI_01985	3.31e-89	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
APFKBCAI_01986	3.25e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
APFKBCAI_01987	6.75e-112	-	-	-	S	-	-	-	Putative esterase
APFKBCAI_01988	6.05e-74	-	-	-	S	-	-	-	Putative esterase
APFKBCAI_01989	1.42e-233	-	-	-	-	-	-	-	-
APFKBCAI_01990	3.09e-133	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
APFKBCAI_01991	1.39e-110	-	-	-	F	-	-	-	NUDIX domain
APFKBCAI_01992	1.89e-220	-	-	-	U	-	-	-	Major Facilitator Superfamily
APFKBCAI_01993	1.42e-49	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
APFKBCAI_01994	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APFKBCAI_01995	2.82e-40	-	-	-	-	-	-	-	-
APFKBCAI_01996	3.53e-188	-	-	-	S	-	-	-	zinc-ribbon domain
APFKBCAI_01997	3.38e-252	pbpX	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_01998	1.77e-239	ydbI	-	-	K	-	-	-	AI-2E family transporter
APFKBCAI_01999	1.19e-163	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
APFKBCAI_02000	2e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
APFKBCAI_02001	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
APFKBCAI_02002	1.17e-217	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
APFKBCAI_02003	1.23e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
APFKBCAI_02004	1.85e-284	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
APFKBCAI_02005	1.23e-170	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
APFKBCAI_02006	8.35e-93	usp1	-	-	T	-	-	-	Universal stress protein family
APFKBCAI_02007	9.92e-317	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
APFKBCAI_02008	3.25e-195	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APFKBCAI_02009	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
APFKBCAI_02010	4.79e-292	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
APFKBCAI_02011	7.67e-83	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APFKBCAI_02012	8.03e-188	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
APFKBCAI_02013	7.02e-286	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
APFKBCAI_02014	1.92e-88	-	-	-	-	-	-	-	-
APFKBCAI_02015	5.76e-212	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
APFKBCAI_02016	1.81e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APFKBCAI_02017	7.71e-276	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
APFKBCAI_02018	3.93e-32	-	-	-	E	-	-	-	lactoylglutathione lyase activity
APFKBCAI_02019	9.23e-155	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
APFKBCAI_02020	1.34e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase family
APFKBCAI_02021	5.73e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_02022	7.57e-226	-	-	-	V	ko:K01421	-	ko00000	domain protein
APFKBCAI_02023	4.41e-220	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APFKBCAI_02024	4.01e-307	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02025	1.1e-71	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02026	9.5e-221	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02027	2.56e-42	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02028	2.87e-87	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
APFKBCAI_02029	3.08e-71	-	-	-	M	-	-	-	SIS domain
APFKBCAI_02030	1.86e-107	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
APFKBCAI_02031	4.42e-60	-	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	arabinose-5-phosphate isomerase activity
APFKBCAI_02032	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
APFKBCAI_02033	3.26e-16	-	-	-	-	-	-	-	-
APFKBCAI_02034	5.92e-261	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
APFKBCAI_02035	1.24e-205	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
APFKBCAI_02036	1.33e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
APFKBCAI_02037	4.52e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APFKBCAI_02038	1.72e-212	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_02039	1.45e-280	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APFKBCAI_02040	3.94e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
APFKBCAI_02041	5.96e-205	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_02042	1.98e-148	-	-	-	I	-	-	-	ABC-2 family transporter protein
APFKBCAI_02043	2.3e-184	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
APFKBCAI_02044	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
APFKBCAI_02045	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_02046	9.88e-205	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
APFKBCAI_02047	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APFKBCAI_02048	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
APFKBCAI_02049	3.68e-97	-	-	-	S	-	-	-	NusG domain II
APFKBCAI_02050	3.34e-232	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
APFKBCAI_02051	2.29e-48	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_02052	3.49e-148	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
APFKBCAI_02053	8.37e-66	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APFKBCAI_02054	7.04e-216	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APFKBCAI_02055	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
APFKBCAI_02056	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APFKBCAI_02057	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
APFKBCAI_02058	2.91e-232	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
APFKBCAI_02059	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
APFKBCAI_02060	3.2e-301	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
APFKBCAI_02061	1.27e-227	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
APFKBCAI_02062	1.18e-50	-	-	-	-	-	-	-	-
APFKBCAI_02063	5.73e-86	-	-	-	-	-	-	-	-
APFKBCAI_02064	4.28e-11	-	-	-	-	-	-	-	-
APFKBCAI_02065	1.57e-34	-	-	-	-	-	-	-	-
APFKBCAI_02066	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
APFKBCAI_02067	2.08e-145	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
APFKBCAI_02068	3.44e-17	-	-	-	-	-	-	-	-
APFKBCAI_02069	1.94e-100	usp5	-	-	T	-	-	-	universal stress protein
APFKBCAI_02070	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
APFKBCAI_02071	1.29e-186	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
APFKBCAI_02072	5.06e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
APFKBCAI_02073	3.64e-83	-	-	-	-	-	-	-	-
APFKBCAI_02074	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
APFKBCAI_02076	5.22e-132	-	-	-	Q	-	-	-	methyltransferase
APFKBCAI_02077	2.41e-145	-	-	-	T	-	-	-	Sh3 type 3 domain protein
APFKBCAI_02078	1.78e-147	-	-	-	F	-	-	-	glutamine amidotransferase
APFKBCAI_02079	1.5e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
APFKBCAI_02080	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
APFKBCAI_02081	2.69e-185	-	-	-	S	-	-	-	Alpha beta hydrolase
APFKBCAI_02082	9.69e-254	-	-	-	I	-	-	-	Acyltransferase
APFKBCAI_02083	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
APFKBCAI_02084	1.31e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
APFKBCAI_02085	5.61e-121	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
APFKBCAI_02086	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APFKBCAI_02087	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APFKBCAI_02088	0.0	ydaO	-	-	E	-	-	-	amino acid
APFKBCAI_02089	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
APFKBCAI_02094	9.82e-200	-	-	-	S	-	-	-	Alpha beta hydrolase
APFKBCAI_02095	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
APFKBCAI_02096	1.28e-165	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_02098	2.33e-206	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
APFKBCAI_02099	5.84e-252	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
APFKBCAI_02100	6.1e-64	-	-	-	-	-	-	-	-
APFKBCAI_02101	3.48e-219	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
APFKBCAI_02102	4.54e-214	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APFKBCAI_02103	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
APFKBCAI_02104	1.3e-49	-	-	-	-	-	-	-	-
APFKBCAI_02105	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
APFKBCAI_02106	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
APFKBCAI_02107	9.28e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
APFKBCAI_02108	1.84e-169	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
APFKBCAI_02109	1.28e-156	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
APFKBCAI_02110	2.21e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
APFKBCAI_02112	0.0	-	-	-	M	-	-	-	LysM domain
APFKBCAI_02114	3.3e-64	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
APFKBCAI_02115	1.13e-45	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
APFKBCAI_02116	2.46e-33	-	-	-	L	-	-	-	Transposase DDE domain group 1
APFKBCAI_02119	1.31e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APFKBCAI_02120	1.79e-148	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
APFKBCAI_02121	7.2e-104	-	-	-	L	-	-	-	Restriction endonuclease EcoRV
APFKBCAI_02122	2.7e-63	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
APFKBCAI_02123	5.8e-111	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	DNA methylase
APFKBCAI_02124	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
APFKBCAI_02125	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
APFKBCAI_02126	2.72e-69	-	-	-	-	-	-	-	-
APFKBCAI_02127	2.59e-55	-	-	-	-	-	-	-	-
APFKBCAI_02128	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
APFKBCAI_02129	6.86e-108	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
APFKBCAI_02130	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
APFKBCAI_02131	2.13e-36	-	-	-	-	-	-	-	-
APFKBCAI_02132	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
APFKBCAI_02133	3.98e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
APFKBCAI_02134	7.8e-107	yjhE	-	-	S	-	-	-	Phage tail protein
APFKBCAI_02135	6.51e-305	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
APFKBCAI_02136	1.77e-235	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
APFKBCAI_02137	1.64e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
APFKBCAI_02138	2.79e-159	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
APFKBCAI_02139	3.01e-46	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
APFKBCAI_02140	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
APFKBCAI_02141	3.26e-175	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02142	0.0	-	-	-	E	-	-	-	Amino Acid
APFKBCAI_02143	4.57e-212	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
APFKBCAI_02144	1.46e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APFKBCAI_02145	2.68e-140	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
APFKBCAI_02146	0.0	-	-	-	M	-	-	-	Sulfatase
APFKBCAI_02147	1.7e-221	-	-	-	S	-	-	-	EpsG family
APFKBCAI_02148	1.13e-107	-	-	-	D	-	-	-	Capsular exopolysaccharide family
APFKBCAI_02149	1.45e-126	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
APFKBCAI_02150	9.53e-248	-	-	-	S	-	-	-	polysaccharide biosynthetic process
APFKBCAI_02151	1.55e-43	-	-	-	S	-	-	-	polysaccharide biosynthetic process
APFKBCAI_02152	2.61e-252	-	-	-	M	-	-	-	Glycosyl transferases group 1
APFKBCAI_02153	2.43e-81	-	-	-	M	-	-	-	Glycosyltransferase like family 2
APFKBCAI_02154	2.64e-44	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
APFKBCAI_02155	2.18e-277	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
APFKBCAI_02156	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
APFKBCAI_02157	7.03e-225	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
APFKBCAI_02158	3.19e-142	-	-	-	M	-	-	-	Acyltransferase family
APFKBCAI_02159	8.66e-202	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
APFKBCAI_02160	1.34e-255	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APFKBCAI_02161	2.25e-107	-	-	-	-	-	-	-	-
APFKBCAI_02162	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
APFKBCAI_02163	5.41e-171	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
APFKBCAI_02164	1.56e-145	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
APFKBCAI_02165	1.88e-224	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
APFKBCAI_02166	7.92e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_02167	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_02168	1.44e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
APFKBCAI_02170	8.66e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02171	1.13e-220	-	-	-	-	-	-	-	-
APFKBCAI_02172	0.000417	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
APFKBCAI_02173	5.53e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
APFKBCAI_02174	1.1e-13	-	-	-	-	-	-	-	-
APFKBCAI_02175	1.79e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
APFKBCAI_02176	1.36e-87	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_02177	2.33e-200	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
APFKBCAI_02178	2.28e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APFKBCAI_02179	3.15e-208	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APFKBCAI_02180	1.38e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
APFKBCAI_02181	2.2e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APFKBCAI_02182	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APFKBCAI_02183	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
APFKBCAI_02184	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
APFKBCAI_02185	8.67e-258	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
APFKBCAI_02186	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APFKBCAI_02187	9.91e-69	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APFKBCAI_02188	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APFKBCAI_02189	1.02e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
APFKBCAI_02190	1.23e-171	-	-	-	M	-	-	-	Sortase family
APFKBCAI_02191	2.06e-183	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APFKBCAI_02192	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
APFKBCAI_02193	3.92e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
APFKBCAI_02194	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
APFKBCAI_02195	5.46e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
APFKBCAI_02196	7.73e-201	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
APFKBCAI_02197	7.15e-95	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
APFKBCAI_02198	3.44e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APFKBCAI_02199	6.87e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APFKBCAI_02200	3.12e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APFKBCAI_02201	1.25e-207	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APFKBCAI_02202	8.1e-80	-	-	-	S	-	-	-	SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
APFKBCAI_02203	1.52e-09	-	-	-	M	-	-	-	Glycosyl transferase 4-like
APFKBCAI_02205	8.15e-90	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
APFKBCAI_02206	5.55e-26	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
APFKBCAI_02207	1.47e-44	-	-	-	M	-	-	-	Glycosyl transferases group 1
APFKBCAI_02208	4.43e-46	-	-	-	S	-	-	-	Glycosyl transferase family 2
APFKBCAI_02209	1.43e-106	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
APFKBCAI_02210	7.18e-144	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
APFKBCAI_02211	6.98e-148	epsB	-	-	M	-	-	-	biosynthesis protein
APFKBCAI_02212	1.23e-169	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
APFKBCAI_02213	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
APFKBCAI_02214	6.57e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
APFKBCAI_02215	2.98e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
APFKBCAI_02216	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
APFKBCAI_02217	2.94e-149	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
APFKBCAI_02218	2.22e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APFKBCAI_02219	2.89e-250	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
APFKBCAI_02220	3.36e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APFKBCAI_02221	1.15e-207	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APFKBCAI_02222	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APFKBCAI_02223	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
APFKBCAI_02224	5.82e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APFKBCAI_02225	1.06e-167	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
APFKBCAI_02226	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
APFKBCAI_02227	9.83e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
APFKBCAI_02228	1.54e-130	-	-	-	-	-	-	-	-
APFKBCAI_02229	6.5e-71	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
APFKBCAI_02230	3.1e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
APFKBCAI_02231	2.25e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
APFKBCAI_02232	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APFKBCAI_02233	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APFKBCAI_02234	1.18e-170	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
APFKBCAI_02235	5.85e-171	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
APFKBCAI_02236	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
APFKBCAI_02237	2.01e-141	-	-	-	-	-	-	-	-
APFKBCAI_02238	1.38e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
APFKBCAI_02239	1.38e-185	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
APFKBCAI_02240	0.0	-	-	-	G	-	-	-	Phosphodiester glycosidase
APFKBCAI_02242	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
APFKBCAI_02243	1.41e-263	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
APFKBCAI_02244	4.88e-283	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
APFKBCAI_02245	1.27e-164	-	-	-	-	-	-	-	-
APFKBCAI_02246	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
APFKBCAI_02247	9.91e-28	-	-	-	-	-	-	-	-
APFKBCAI_02249	1.32e-270	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
APFKBCAI_02252	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
APFKBCAI_02253	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
APFKBCAI_02254	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
APFKBCAI_02255	8.92e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
APFKBCAI_02256	2.32e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
APFKBCAI_02257	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
APFKBCAI_02258	3.31e-143	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
APFKBCAI_02259	1.34e-147	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APFKBCAI_02260	7.79e-112	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
APFKBCAI_02261	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
APFKBCAI_02262	1.71e-155	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APFKBCAI_02263	2.19e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
APFKBCAI_02264	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APFKBCAI_02266	7.13e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
APFKBCAI_02267	4.44e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
APFKBCAI_02268	5.13e-46	-	-	-	-	-	-	-	-
APFKBCAI_02269	1.66e-247	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
APFKBCAI_02270	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
APFKBCAI_02271	6.22e-211	lysR	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_02272	1.46e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APFKBCAI_02273	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APFKBCAI_02274	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
APFKBCAI_02275	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_02276	1.9e-72	-	-	-	-	-	-	-	-
APFKBCAI_02277	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APFKBCAI_02278	9.94e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
APFKBCAI_02279	2.28e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
APFKBCAI_02280	1.16e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
APFKBCAI_02281	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
APFKBCAI_02282	5.71e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APFKBCAI_02283	1.74e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
APFKBCAI_02285	7.77e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APFKBCAI_02286	3.31e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
APFKBCAI_02287	1.44e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
APFKBCAI_02288	1.94e-306	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APFKBCAI_02289	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
APFKBCAI_02290	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
APFKBCAI_02291	7.99e-195	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APFKBCAI_02292	1.27e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APFKBCAI_02293	1.9e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APFKBCAI_02294	1.91e-245	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
APFKBCAI_02295	1.43e-67	-	-	-	S	-	-	-	MazG-like family
APFKBCAI_02296	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
APFKBCAI_02298	5.1e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
APFKBCAI_02299	1.55e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
APFKBCAI_02300	2.07e-262	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
APFKBCAI_02301	2.12e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APFKBCAI_02302	7.73e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APFKBCAI_02303	8.89e-288	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APFKBCAI_02304	1.21e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
APFKBCAI_02305	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APFKBCAI_02306	2.78e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APFKBCAI_02307	8.59e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APFKBCAI_02308	3.38e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
APFKBCAI_02309	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
APFKBCAI_02310	5.29e-262	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APFKBCAI_02311	1.97e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
APFKBCAI_02312	1.76e-145	-	-	-	C	-	-	-	Nitroreductase family
APFKBCAI_02313	1.22e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_02314	7.37e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_02315	2.23e-279	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
APFKBCAI_02316	4.31e-165	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APFKBCAI_02317	1.95e-221	-	-	-	T	-	-	-	Histidine kinase-like ATPases
APFKBCAI_02318	4.44e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02319	7.18e-49	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
APFKBCAI_02320	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
APFKBCAI_02321	1.36e-265	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
APFKBCAI_02322	1.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
APFKBCAI_02323	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
APFKBCAI_02324	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APFKBCAI_02325	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
APFKBCAI_02326	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APFKBCAI_02327	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APFKBCAI_02328	5.07e-143	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APFKBCAI_02329	7.64e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
APFKBCAI_02330	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APFKBCAI_02331	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APFKBCAI_02332	5.78e-215	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
APFKBCAI_02333	3.78e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APFKBCAI_02334	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APFKBCAI_02335	4.31e-37	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
APFKBCAI_02336	2.98e-130	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
APFKBCAI_02337	2.79e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APFKBCAI_02338	1.84e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APFKBCAI_02339	3.35e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
APFKBCAI_02340	2.8e-12	-	-	-	-	-	-	-	-
APFKBCAI_02341	1.11e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APFKBCAI_02342	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
APFKBCAI_02343	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
APFKBCAI_02344	2.34e-124	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APFKBCAI_02345	1.76e-146	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
APFKBCAI_02346	2.24e-201	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
APFKBCAI_02347	1.18e-191	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
APFKBCAI_02348	4.5e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
APFKBCAI_02349	6.29e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APFKBCAI_02350	2.17e-246	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APFKBCAI_02351	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02352	5.96e-110	-	-	-	-	-	-	-	-
APFKBCAI_02353	1.98e-160	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APFKBCAI_02354	1.35e-101	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APFKBCAI_02355	2.95e-207	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APFKBCAI_02356	1.64e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
APFKBCAI_02357	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APFKBCAI_02358	3.67e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
APFKBCAI_02359	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
APFKBCAI_02360	4.45e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
APFKBCAI_02361	7.22e-86	-	-	-	M	-	-	-	Lysin motif
APFKBCAI_02362	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
APFKBCAI_02363	5.09e-238	-	-	-	S	-	-	-	Helix-turn-helix domain
APFKBCAI_02364	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
APFKBCAI_02365	5.3e-124	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APFKBCAI_02366	3.03e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
APFKBCAI_02367	1.1e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APFKBCAI_02368	8.93e-163	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APFKBCAI_02369	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APFKBCAI_02370	1.21e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
APFKBCAI_02371	1.47e-208	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
APFKBCAI_02372	6.13e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
APFKBCAI_02373	3.85e-71	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
APFKBCAI_02374	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
APFKBCAI_02375	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APFKBCAI_02376	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
APFKBCAI_02377	2.06e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
APFKBCAI_02378	7.5e-188	-	-	-	-	-	-	-	-
APFKBCAI_02379	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
APFKBCAI_02380	3.83e-56	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
APFKBCAI_02381	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
APFKBCAI_02382	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APFKBCAI_02383	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
APFKBCAI_02384	4.46e-182	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
APFKBCAI_02385	3.56e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APFKBCAI_02386	0.0	oatA	-	-	I	-	-	-	Acyltransferase
APFKBCAI_02387	1.29e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APFKBCAI_02388	4.8e-171	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
APFKBCAI_02389	5.35e-216	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
APFKBCAI_02390	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
APFKBCAI_02392	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APFKBCAI_02393	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02394	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_02395	2.34e-28	-	-	-	-	-	-	-	-
APFKBCAI_02396	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
APFKBCAI_02397	1.21e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
APFKBCAI_02398	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APFKBCAI_02399	2.78e-269	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APFKBCAI_02400	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
APFKBCAI_02401	1.32e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APFKBCAI_02402	2.21e-309	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
APFKBCAI_02403	8.07e-204	-	-	-	K	-	-	-	LysR substrate binding domain
APFKBCAI_02404	3.13e-99	-	-	-	-	-	-	-	-
APFKBCAI_02405	2.37e-95	-	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_02406	3.68e-311	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
APFKBCAI_02407	1.22e-165	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
APFKBCAI_02409	7.84e-317	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02410	6.21e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02411	4.19e-89	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02412	1.86e-154	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
APFKBCAI_02413	1.86e-212	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
APFKBCAI_02414	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
APFKBCAI_02415	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
APFKBCAI_02416	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APFKBCAI_02417	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
APFKBCAI_02418	4.24e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
APFKBCAI_02419	1.23e-274	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
APFKBCAI_02420	1.35e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
APFKBCAI_02421	9.19e-155	-	-	-	-	-	-	-	-
APFKBCAI_02422	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APFKBCAI_02423	0.0	-	-	-	M	-	-	-	Right handed beta helix region
APFKBCAI_02424	1.09e-98	-	-	-	-	-	-	-	-
APFKBCAI_02425	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
APFKBCAI_02427	1.78e-86	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
APFKBCAI_02428	7.09e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APFKBCAI_02429	4.89e-172	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APFKBCAI_02430	1.2e-105	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APFKBCAI_02431	3.82e-258	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
APFKBCAI_02432	1.2e-129	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
APFKBCAI_02433	6.48e-140	-	-	-	K	-	-	-	Bacterial transcriptional regulator
APFKBCAI_02434	6.27e-182	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APFKBCAI_02435	2.15e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APFKBCAI_02436	8.35e-115	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
APFKBCAI_02437	8e-192	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
APFKBCAI_02438	8.99e-157	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APFKBCAI_02440	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
APFKBCAI_02441	5.82e-250	-	-	-	G	-	-	-	Melibiase
APFKBCAI_02442	6.48e-52	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APFKBCAI_02443	5.55e-83	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APFKBCAI_02444	2.21e-79	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APFKBCAI_02445	4.58e-30	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
APFKBCAI_02446	6.05e-65	araR	-	-	K	ko:K02103	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
APFKBCAI_02447	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
APFKBCAI_02448	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
APFKBCAI_02450	1.47e-160	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APFKBCAI_02451	4.98e-107	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
APFKBCAI_02452	5.63e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
APFKBCAI_02453	3.56e-259	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
APFKBCAI_02454	6.07e-275	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
APFKBCAI_02455	3.36e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
APFKBCAI_02456	2.89e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
APFKBCAI_02457	1.66e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
APFKBCAI_02458	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
APFKBCAI_02459	1.62e-71	-	-	-	S	-	-	-	PRD domain
APFKBCAI_02460	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
APFKBCAI_02461	4.85e-158	-	-	-	H	-	-	-	Pfam:Transaldolase
APFKBCAI_02462	1.74e-82	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
APFKBCAI_02463	5.39e-252	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
APFKBCAI_02464	1.43e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
APFKBCAI_02465	4.36e-114	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
APFKBCAI_02466	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
APFKBCAI_02467	8.33e-185	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
APFKBCAI_02468	2.14e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
APFKBCAI_02469	1.02e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APFKBCAI_02470	5.14e-214	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
APFKBCAI_02471	3.66e-177	-	-	-	K	-	-	-	DeoR C terminal sensor domain
APFKBCAI_02472	7.47e-148	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
APFKBCAI_02473	6.78e-61	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02474	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02475	2.42e-105	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02476	1.21e-270	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
APFKBCAI_02477	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
APFKBCAI_02478	9.05e-55	-	-	-	-	-	-	-	-
APFKBCAI_02479	1.69e-200	-	-	-	GK	-	-	-	ROK family
APFKBCAI_02480	1.5e-230	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
APFKBCAI_02481	2.27e-315	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
APFKBCAI_02482	5.02e-168	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
APFKBCAI_02483	2.05e-16	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
APFKBCAI_02484	7.84e-226	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
APFKBCAI_02485	9.84e-264	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
APFKBCAI_02486	4.6e-196	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
APFKBCAI_02487	2.26e-144	-	-	-	S	-	-	-	DJ-1/PfpI family
APFKBCAI_02488	5.87e-62	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
APFKBCAI_02489	6.5e-119	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
APFKBCAI_02490	4.16e-143	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
APFKBCAI_02491	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
APFKBCAI_02492	5.05e-171	-	-	-	F	-	-	-	NUDIX domain
APFKBCAI_02493	9.35e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
APFKBCAI_02494	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APFKBCAI_02495	2.14e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
APFKBCAI_02496	5.05e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APFKBCAI_02497	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
APFKBCAI_02498	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_02499	1.76e-208	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
APFKBCAI_02500	3.09e-267	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
APFKBCAI_02501	1.94e-288	-	-	-	EGP	-	-	-	Transmembrane secretion effector
APFKBCAI_02502	4.15e-187	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
APFKBCAI_02503	1.04e-243	-	-	-	V	-	-	-	Beta-lactamase
APFKBCAI_02504	1.53e-187	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APFKBCAI_02505	1.1e-209	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
APFKBCAI_02506	7.93e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APFKBCAI_02507	5.03e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
APFKBCAI_02508	1.88e-168	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APFKBCAI_02510	7.17e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
APFKBCAI_02511	1.65e-213	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
APFKBCAI_02512	9.84e-184	-	-	-	Q	-	-	-	Methyltransferase
APFKBCAI_02513	1.25e-67	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
APFKBCAI_02514	2.44e-07	-	-	-	K	-	-	-	SpoVT / AbrB like domain
APFKBCAI_02515	4.22e-173	-	-	-	V	-	-	-	ABC transporter transmembrane region
APFKBCAI_02516	1.33e-77	-	-	-	-	-	-	-	-
APFKBCAI_02517	1.78e-49	-	-	-	-	-	-	-	-
APFKBCAI_02518	1.4e-140	-	-	-	S	-	-	-	alpha beta
APFKBCAI_02519	3.49e-113	yfbM	-	-	K	-	-	-	FR47-like protein
APFKBCAI_02520	3.24e-169	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
APFKBCAI_02521	2.21e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
APFKBCAI_02522	1.45e-159	-	-	-	-	-	-	-	-
APFKBCAI_02523	1.7e-53	-	-	-	S	-	-	-	ASCH
APFKBCAI_02524	6.31e-16	-	-	-	S	-	-	-	ASCH
APFKBCAI_02525	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APFKBCAI_02526	7.69e-254	ysdE	-	-	P	-	-	-	Citrate transporter
APFKBCAI_02527	1.17e-136	-	-	-	-	-	-	-	-
APFKBCAI_02528	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
APFKBCAI_02529	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APFKBCAI_02530	2.7e-204	-	-	-	-	-	-	-	-
APFKBCAI_02531	0.0	cadA	-	-	P	-	-	-	P-type ATPase
APFKBCAI_02532	3.36e-98	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
APFKBCAI_02533	1.94e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
APFKBCAI_02534	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
APFKBCAI_02536	2.29e-244	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
APFKBCAI_02538	1.91e-316	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
APFKBCAI_02539	1.41e-77	-	-	-	-	-	-	-	-
APFKBCAI_02540	6.43e-106	-	-	-	-	-	-	-	-
APFKBCAI_02541	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
APFKBCAI_02542	2.21e-42	-	-	-	-	-	-	-	-
APFKBCAI_02543	1.34e-121	-	-	-	S	-	-	-	acetyltransferase
APFKBCAI_02544	0.0	yclK	-	-	T	-	-	-	Histidine kinase
APFKBCAI_02545	2.91e-125	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
APFKBCAI_02546	1.55e-91	-	-	-	S	-	-	-	SdpI/YhfL protein family
APFKBCAI_02548	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
APFKBCAI_02549	1.45e-207	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
APFKBCAI_02550	8.68e-229	arbY	-	-	M	-	-	-	family 8
APFKBCAI_02551	6.75e-211	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
APFKBCAI_02552	1.34e-184	arbV	-	-	I	-	-	-	Phosphate acyltransferases
APFKBCAI_02553	1.74e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
APFKBCAI_02554	4.7e-94	-	-	-	-	-	-	-	-
APFKBCAI_02555	2.23e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
APFKBCAI_02556	3.74e-59	-	-	-	-	-	-	-	-
APFKBCAI_02557	4.66e-100	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
APFKBCAI_02558	3.45e-63	-	-	-	-	-	-	-	-
APFKBCAI_02560	2.85e-64	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
APFKBCAI_02561	2.08e-215	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
APFKBCAI_02562	6.78e-175	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
APFKBCAI_02563	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
APFKBCAI_02564	5.18e-119	-	-	-	S	-	-	-	VanZ like family
APFKBCAI_02565	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
APFKBCAI_02566	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APFKBCAI_02567	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APFKBCAI_02568	2.39e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
APFKBCAI_02569	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APFKBCAI_02570	4.27e-167	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APFKBCAI_02571	1.02e-244	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_02572	3.12e-151	-	-	-	K	-	-	-	Transcriptional regulator
APFKBCAI_02573	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
APFKBCAI_02576	5.98e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
APFKBCAI_02577	1.67e-185	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_02578	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
APFKBCAI_02579	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APFKBCAI_02580	4.84e-125	-	-	-	K	-	-	-	Cupin domain
APFKBCAI_02581	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
APFKBCAI_02582	3.91e-201	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
APFKBCAI_02583	5.5e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
APFKBCAI_02584	1.9e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
APFKBCAI_02585	1.14e-208	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APFKBCAI_02586	8.34e-44	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
APFKBCAI_02587	5.34e-213	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02588	4.87e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
APFKBCAI_02589	1.82e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
APFKBCAI_02590	4.68e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APFKBCAI_02591	4.87e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APFKBCAI_02592	5.33e-119	-	-	-	-	-	-	-	-
APFKBCAI_02593	1.6e-133	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
APFKBCAI_02594	6.04e-249	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
APFKBCAI_02595	3.2e-27	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
APFKBCAI_02596	7.6e-157	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
APFKBCAI_02597	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
APFKBCAI_02598	5.23e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
APFKBCAI_02599	1.03e-305	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
APFKBCAI_02601	5.27e-64	-	-	-	-	-	-	-	-
APFKBCAI_02602	8.3e-150	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
APFKBCAI_02603	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
APFKBCAI_02604	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
APFKBCAI_02605	9.03e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APFKBCAI_02606	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APFKBCAI_02607	1.29e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
APFKBCAI_02608	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
APFKBCAI_02609	1.48e-78	-	-	-	-	-	-	-	-
APFKBCAI_02610	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
APFKBCAI_02611	2.17e-81	-	-	-	-	-	-	-	-
APFKBCAI_02612	2.39e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APFKBCAI_02613	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APFKBCAI_02614	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
APFKBCAI_02615	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APFKBCAI_02616	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
APFKBCAI_02618	1.71e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APFKBCAI_02619	6.45e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
APFKBCAI_02620	3.36e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
APFKBCAI_02621	2.87e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
APFKBCAI_02622	1.21e-212	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
APFKBCAI_02623	6.02e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
APFKBCAI_02624	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APFKBCAI_02625	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APFKBCAI_02626	4.68e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
APFKBCAI_02627	2.85e-300	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
APFKBCAI_02628	4.02e-116	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
APFKBCAI_02629	7.64e-142	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
APFKBCAI_02630	7.27e-108	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
APFKBCAI_02631	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
APFKBCAI_02632	4.84e-229	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APFKBCAI_02633	2.2e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
APFKBCAI_02634	2e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APFKBCAI_02635	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APFKBCAI_02636	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
APFKBCAI_02637	4.06e-48	-	-	-	-	-	-	-	-
APFKBCAI_02638	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
APFKBCAI_02639	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
APFKBCAI_02640	1.18e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APFKBCAI_02641	6.38e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APFKBCAI_02642	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
APFKBCAI_02643	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
APFKBCAI_02644	4.5e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
APFKBCAI_02645	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
APFKBCAI_02646	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
APFKBCAI_02647	7.12e-254	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
APFKBCAI_02648	4.82e-128	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APFKBCAI_02649	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
APFKBCAI_02650	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APFKBCAI_02651	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APFKBCAI_02652	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APFKBCAI_02653	1.8e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
APFKBCAI_02654	1.51e-297	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
APFKBCAI_02655	6.12e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
APFKBCAI_02656	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
APFKBCAI_02657	2.24e-98	-	-	-	L	-	-	-	Resolvase, N-terminal
APFKBCAI_02661	3.26e-176	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
APFKBCAI_02662	4.77e-60	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
APFKBCAI_02663	1.02e-191	-	-	-	S	-	-	-	hydrolase
APFKBCAI_02664	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
APFKBCAI_02665	8.62e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
APFKBCAI_02666	1.82e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
APFKBCAI_02667	5.12e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
APFKBCAI_02668	1.2e-187	-	-	-	M	-	-	-	hydrolase, family 25
APFKBCAI_02669	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
APFKBCAI_02671	6.02e-163	-	-	-	-	-	-	-	-
APFKBCAI_02672	5.26e-73	-	-	-	C	-	-	-	nitroreductase
APFKBCAI_02673	1.74e-15	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
APFKBCAI_02674	3.15e-241	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02675	2.4e-92	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
APFKBCAI_02676	8.31e-110	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
APFKBCAI_02677	1.23e-233	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02678	3.78e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02679	1.53e-56	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02680	8.9e-83	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
APFKBCAI_02681	2.63e-272	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02682	3.24e-241	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
APFKBCAI_02683	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02684	4.85e-80	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02685	1.3e-244	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
APFKBCAI_02686	2.53e-144	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
APFKBCAI_02687	1.18e-160	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
APFKBCAI_02688	1.38e-210	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
APFKBCAI_02689	1.21e-60	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02690	2.9e-79	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02691	2.95e-213	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APFKBCAI_02692	1.08e-35	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
APFKBCAI_02693	1.74e-288	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
APFKBCAI_02694	1.63e-66	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
APFKBCAI_02695	1.17e-55	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
APFKBCAI_02696	2.67e-11	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
APFKBCAI_02698	1.28e-46	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
APFKBCAI_02699	5.83e-262	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
APFKBCAI_02700	4.21e-277	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
APFKBCAI_02701	1.66e-84	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
APFKBCAI_02702	1.54e-166	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
APFKBCAI_02703	4.79e-35	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APFKBCAI_02704	3.85e-230	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02705	8e-41	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02706	3.97e-73	gntR	-	-	K	-	-	-	rpiR family
APFKBCAI_02707	3.37e-67	-	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
APFKBCAI_02708	1.62e-81	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
APFKBCAI_02709	4.95e-39	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02710	1.47e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02711	2.02e-236	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	iic component
APFKBCAI_02713	4.63e-124	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
APFKBCAI_02714	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
APFKBCAI_02715	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
APFKBCAI_02716	4.15e-312	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
APFKBCAI_02717	8.63e-192	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
APFKBCAI_02718	6.13e-190	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
APFKBCAI_02719	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
APFKBCAI_02720	2.03e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
APFKBCAI_02721	3.73e-203	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
APFKBCAI_02722	1.12e-189	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APFKBCAI_02723	5.62e-191	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
APFKBCAI_02724	6.96e-178	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
APFKBCAI_02725	2.85e-103	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
APFKBCAI_02726	2.14e-81	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
APFKBCAI_02727	6.9e-168	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
APFKBCAI_02728	2.81e-209	-	-	-	K	-	-	-	sugar-binding domain protein
APFKBCAI_02729	4.9e-303	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
APFKBCAI_02730	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
APFKBCAI_02731	2.62e-198	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APFKBCAI_02732	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APFKBCAI_02733	1.77e-198	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02734	9e-160	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
APFKBCAI_02735	2.78e-117	fabG10	1.1.1.100, 1.3.1.28	-	IQ	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
APFKBCAI_02736	5.7e-223	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
APFKBCAI_02737	2.51e-48	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APFKBCAI_02738	7.94e-112	-	-	-	G	-	-	-	DeoC/LacD family aldolase
APFKBCAI_02739	2.13e-152	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
APFKBCAI_02741	9.09e-270	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
APFKBCAI_02742	1.32e-199	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
APFKBCAI_02743	7.76e-113	-	-	-	S	-	-	-	Zeta toxin
APFKBCAI_02744	2.67e-191	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
APFKBCAI_02745	4.31e-55	-	-	-	-	-	-	-	-
APFKBCAI_02746	4.22e-287	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
APFKBCAI_02747	1.27e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
APFKBCAI_02748	1.34e-205	-	-	-	GKT	-	-	-	transcriptional antiterminator
APFKBCAI_02749	3.75e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
APFKBCAI_02750	8.52e-41	-	-	-	-	-	-	-	-
APFKBCAI_02751	2.9e-134	-	-	-	-	-	-	-	-
APFKBCAI_02752	5.81e-91	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
APFKBCAI_02753	1.79e-303	-	-	-	EGP	-	-	-	Major Facilitator
APFKBCAI_02754	2.02e-116	-	-	-	-	-	-	-	-
APFKBCAI_02755	5.1e-77	-	-	-	-	-	-	-	-
APFKBCAI_02756	2.78e-99	-	-	-	-	-	-	-	-
APFKBCAI_02757	8.43e-112	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
APFKBCAI_02758	7.78e-69	-	-	-	-	-	-	-	-
APFKBCAI_02759	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
APFKBCAI_02760	4.01e-52	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
APFKBCAI_02761	4.69e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APFKBCAI_02762	7.61e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
APFKBCAI_02763	2.36e-205	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
APFKBCAI_02764	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APFKBCAI_02765	2.78e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APFKBCAI_02766	4.71e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
APFKBCAI_02767	0.0	-	-	-	E	-	-	-	Amino acid permease
APFKBCAI_02768	7.09e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
APFKBCAI_02769	3.38e-133	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APFKBCAI_02770	2.69e-192	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APFKBCAI_02771	8.48e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
APFKBCAI_02772	3.83e-163	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APFKBCAI_02773	3.26e-143	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
APFKBCAI_02774	1.1e-310	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
APFKBCAI_02775	1.86e-122	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
APFKBCAI_02776	5.22e-214	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
APFKBCAI_02777	2.23e-155	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
APFKBCAI_02779	9.5e-156	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
APFKBCAI_02780	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
APFKBCAI_02781	2.34e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides