ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PHEDMDMH_00001 2.73e-92 - - - - - - - -
PHEDMDMH_00002 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PHEDMDMH_00003 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHEDMDMH_00004 8.12e-306 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
PHEDMDMH_00005 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
PHEDMDMH_00006 7.14e-183 - - - - - - - -
PHEDMDMH_00007 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
PHEDMDMH_00008 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHEDMDMH_00009 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHEDMDMH_00010 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
PHEDMDMH_00011 2.21e-56 - - - - - - - -
PHEDMDMH_00012 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
PHEDMDMH_00013 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
PHEDMDMH_00014 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
PHEDMDMH_00015 7.54e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PHEDMDMH_00016 1.17e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PHEDMDMH_00017 2.13e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
PHEDMDMH_00018 7.87e-243 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
PHEDMDMH_00019 1.22e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
PHEDMDMH_00020 2.92e-258 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
PHEDMDMH_00021 5.16e-271 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
PHEDMDMH_00022 9.23e-270 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
PHEDMDMH_00023 6.14e-53 - - - - - - - -
PHEDMDMH_00024 2.37e-294 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_00025 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
PHEDMDMH_00026 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
PHEDMDMH_00027 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
PHEDMDMH_00028 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
PHEDMDMH_00029 2.98e-90 - - - - - - - -
PHEDMDMH_00030 1.22e-125 - - - - - - - -
PHEDMDMH_00031 5.92e-67 - - - - - - - -
PHEDMDMH_00032 1.96e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PHEDMDMH_00033 2.84e-110 - - - - - - - -
PHEDMDMH_00034 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
PHEDMDMH_00035 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_00036 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
PHEDMDMH_00037 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHEDMDMH_00038 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHEDMDMH_00039 4.94e-126 - - - K - - - Helix-turn-helix domain
PHEDMDMH_00040 1.37e-283 - - - C - - - FAD dependent oxidoreductase
PHEDMDMH_00041 9.01e-221 - - - P - - - Major Facilitator Superfamily
PHEDMDMH_00042 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHEDMDMH_00043 1.2e-91 - - - - - - - -
PHEDMDMH_00044 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHEDMDMH_00045 1.77e-200 dkgB - - S - - - reductase
PHEDMDMH_00046 2.28e-114 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PHEDMDMH_00047 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00048 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PHEDMDMH_00049 1.75e-149 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
PHEDMDMH_00050 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
PHEDMDMH_00051 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHEDMDMH_00052 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHEDMDMH_00053 3.81e-18 - - - - - - - -
PHEDMDMH_00054 6.12e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHEDMDMH_00055 4.56e-210 fbpA - - K - - - Domain of unknown function (DUF814)
PHEDMDMH_00056 1.35e-78 - - - S - - - Domain of unknown function (DU1801)
PHEDMDMH_00057 6.33e-46 - - - - - - - -
PHEDMDMH_00058 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
PHEDMDMH_00059 1.11e-146 pgm1 - - G - - - phosphoglycerate mutase
PHEDMDMH_00060 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PHEDMDMH_00061 1.19e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHEDMDMH_00062 1.31e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PHEDMDMH_00063 7.83e-38 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_00064 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_00065 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_00066 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
PHEDMDMH_00068 0.0 - - - M - - - domain protein
PHEDMDMH_00069 2.22e-207 mleR - - K - - - LysR substrate binding domain
PHEDMDMH_00070 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHEDMDMH_00071 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
PHEDMDMH_00072 1.92e-209 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
PHEDMDMH_00073 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHEDMDMH_00074 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
PHEDMDMH_00075 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PHEDMDMH_00076 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHEDMDMH_00077 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
PHEDMDMH_00078 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
PHEDMDMH_00079 9.17e-52 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
PHEDMDMH_00080 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
PHEDMDMH_00081 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
PHEDMDMH_00082 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHEDMDMH_00083 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
PHEDMDMH_00084 2.91e-190 malA - - S - - - maltodextrose utilization protein MalA
PHEDMDMH_00085 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00086 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_00087 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHEDMDMH_00088 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
PHEDMDMH_00089 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
PHEDMDMH_00090 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
PHEDMDMH_00091 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHEDMDMH_00092 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
PHEDMDMH_00093 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
PHEDMDMH_00094 1.58e-238 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
PHEDMDMH_00095 9.56e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
PHEDMDMH_00096 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00097 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
PHEDMDMH_00098 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
PHEDMDMH_00099 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
PHEDMDMH_00100 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
PHEDMDMH_00101 6.03e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_00102 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
PHEDMDMH_00103 3.37e-115 - - - - - - - -
PHEDMDMH_00104 2.42e-89 - - - - - - - -
PHEDMDMH_00105 1.71e-88 - - - - - - - -
PHEDMDMH_00106 6.08e-180 - - - - - - - -
PHEDMDMH_00107 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
PHEDMDMH_00108 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
PHEDMDMH_00110 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
PHEDMDMH_00111 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00112 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
PHEDMDMH_00113 6.49e-268 - - - C - - - Oxidoreductase
PHEDMDMH_00114 0.0 - - - - - - - -
PHEDMDMH_00115 4.29e-102 - - - - - - - -
PHEDMDMH_00116 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
PHEDMDMH_00117 1.92e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
PHEDMDMH_00118 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
PHEDMDMH_00119 2.16e-204 morA - - S - - - reductase
PHEDMDMH_00121 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
PHEDMDMH_00122 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_00123 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
PHEDMDMH_00124 5.51e-106 - - - S - - - Protein of unknown function (DUF3021)
PHEDMDMH_00125 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PHEDMDMH_00126 2.11e-97 - - - K - - - Transcriptional regulator
PHEDMDMH_00127 1.72e-142 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PHEDMDMH_00128 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PHEDMDMH_00129 5.46e-183 - - - F - - - Phosphorylase superfamily
PHEDMDMH_00130 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
PHEDMDMH_00131 9.93e-127 - - - S - - - CRISPR-associated protein (Cas_Csn2)
PHEDMDMH_00132 5.67e-64 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHEDMDMH_00133 1.23e-199 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHEDMDMH_00134 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHEDMDMH_00135 4.17e-191 - - - I - - - Alpha/beta hydrolase family
PHEDMDMH_00136 1.27e-159 - - - - - - - -
PHEDMDMH_00137 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
PHEDMDMH_00138 5.04e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
PHEDMDMH_00139 0.0 - - - L - - - HIRAN domain
PHEDMDMH_00140 3.4e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
PHEDMDMH_00141 4.15e-261 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
PHEDMDMH_00142 1.48e-140 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PHEDMDMH_00143 1.18e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PHEDMDMH_00144 9.25e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PHEDMDMH_00146 1.23e-227 - - - C - - - Zinc-binding dehydrogenase
PHEDMDMH_00147 5.24e-193 larE - - S ko:K06864 - ko00000 NAD synthase
PHEDMDMH_00148 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHEDMDMH_00149 1.75e-98 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
PHEDMDMH_00150 2.9e-178 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PHEDMDMH_00151 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
PHEDMDMH_00152 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
PHEDMDMH_00153 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
PHEDMDMH_00154 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
PHEDMDMH_00155 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PHEDMDMH_00156 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_00157 1.67e-54 - - - - - - - -
PHEDMDMH_00158 5.66e-184 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PHEDMDMH_00159 4.07e-05 - - - - - - - -
PHEDMDMH_00160 2.4e-180 - - - - - - - -
PHEDMDMH_00161 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
PHEDMDMH_00162 2.38e-99 - - - - - - - -
PHEDMDMH_00163 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
PHEDMDMH_00164 5.21e-214 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
PHEDMDMH_00165 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
PHEDMDMH_00166 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_00167 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
PHEDMDMH_00168 1.4e-162 - - - S - - - DJ-1/PfpI family
PHEDMDMH_00169 7.65e-121 yfbM - - K - - - FR47-like protein
PHEDMDMH_00170 4.28e-195 - - - EG - - - EamA-like transporter family
PHEDMDMH_00171 2.84e-81 - - - S - - - Protein of unknown function
PHEDMDMH_00172 7.44e-51 - - - S - - - Protein of unknown function
PHEDMDMH_00173 0.0 fusA1 - - J - - - elongation factor G
PHEDMDMH_00174 6.65e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PHEDMDMH_00175 1.67e-220 - - - K - - - WYL domain
PHEDMDMH_00176 4.35e-165 - - - F - - - glutamine amidotransferase
PHEDMDMH_00177 1.36e-105 - - - S - - - ASCH
PHEDMDMH_00178 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
PHEDMDMH_00179 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHEDMDMH_00180 0.0 - - - S - - - Putative threonine/serine exporter
PHEDMDMH_00181 1.27e-247 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHEDMDMH_00182 1.56e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
PHEDMDMH_00183 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
PHEDMDMH_00184 5.07e-157 ydgI - - C - - - Nitroreductase family
PHEDMDMH_00185 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
PHEDMDMH_00186 1.66e-210 - - - S - - - KR domain
PHEDMDMH_00187 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHEDMDMH_00188 2.49e-95 - - - C - - - FMN binding
PHEDMDMH_00189 1.46e-204 - - - K - - - LysR family
PHEDMDMH_00190 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PHEDMDMH_00191 0.0 - - - C - - - FMN_bind
PHEDMDMH_00192 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
PHEDMDMH_00193 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
PHEDMDMH_00194 1.34e-153 pnb - - C - - - nitroreductase
PHEDMDMH_00195 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
PHEDMDMH_00196 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PHEDMDMH_00197 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
PHEDMDMH_00198 2.84e-123 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00199 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHEDMDMH_00200 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
PHEDMDMH_00201 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
PHEDMDMH_00202 3.54e-195 yycI - - S - - - YycH protein
PHEDMDMH_00203 3.55e-313 yycH - - S - - - YycH protein
PHEDMDMH_00204 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PHEDMDMH_00205 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PHEDMDMH_00207 2.54e-50 - - - - - - - -
PHEDMDMH_00208 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
PHEDMDMH_00209 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
PHEDMDMH_00210 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
PHEDMDMH_00211 2.59e-153 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
PHEDMDMH_00212 2.4e-183 - - - S - - - haloacid dehalogenase-like hydrolase
PHEDMDMH_00214 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PHEDMDMH_00215 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PHEDMDMH_00216 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
PHEDMDMH_00217 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
PHEDMDMH_00218 5.02e-277 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PHEDMDMH_00219 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PHEDMDMH_00220 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_00222 1.88e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PHEDMDMH_00223 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHEDMDMH_00224 4.96e-289 yttB - - EGP - - - Major Facilitator
PHEDMDMH_00225 4.03e-315 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PHEDMDMH_00226 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
PHEDMDMH_00227 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PHEDMDMH_00228 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHEDMDMH_00229 1.59e-95 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHEDMDMH_00230 1.71e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PHEDMDMH_00231 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHEDMDMH_00232 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHEDMDMH_00233 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHEDMDMH_00234 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
PHEDMDMH_00235 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHEDMDMH_00236 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHEDMDMH_00237 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
PHEDMDMH_00238 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHEDMDMH_00239 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHEDMDMH_00240 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_00241 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
PHEDMDMH_00242 1.3e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
PHEDMDMH_00243 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHEDMDMH_00244 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHEDMDMH_00245 1.31e-143 - - - S - - - Cell surface protein
PHEDMDMH_00246 1.29e-210 - - - S - - - Bacterial protein of unknown function (DUF916)
PHEDMDMH_00248 0.0 - - - - - - - -
PHEDMDMH_00249 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PHEDMDMH_00251 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
PHEDMDMH_00252 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
PHEDMDMH_00253 4.69e-202 degV1 - - S - - - DegV family
PHEDMDMH_00254 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
PHEDMDMH_00255 6.11e-187 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
PHEDMDMH_00256 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
PHEDMDMH_00257 7.43e-130 padR - - K - - - Virulence activator alpha C-term
PHEDMDMH_00258 2.51e-103 - - - T - - - Universal stress protein family
PHEDMDMH_00259 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
PHEDMDMH_00260 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PHEDMDMH_00261 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHEDMDMH_00262 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PHEDMDMH_00263 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
PHEDMDMH_00264 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
PHEDMDMH_00265 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PHEDMDMH_00266 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
PHEDMDMH_00267 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
PHEDMDMH_00268 5.88e-233 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
PHEDMDMH_00269 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
PHEDMDMH_00270 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PHEDMDMH_00271 5.03e-95 - - - K - - - Transcriptional regulator
PHEDMDMH_00272 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PHEDMDMH_00273 4.64e-255 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PHEDMDMH_00275 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
PHEDMDMH_00276 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
PHEDMDMH_00277 9.62e-19 - - - - - - - -
PHEDMDMH_00278 2.18e-211 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHEDMDMH_00279 7.42e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PHEDMDMH_00280 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
PHEDMDMH_00281 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
PHEDMDMH_00282 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
PHEDMDMH_00283 1.06e-16 - - - - - - - -
PHEDMDMH_00284 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
PHEDMDMH_00285 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
PHEDMDMH_00286 2.28e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
PHEDMDMH_00287 2.13e-159 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PHEDMDMH_00288 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PHEDMDMH_00289 4.66e-197 nanK - - GK - - - ROK family
PHEDMDMH_00290 9.03e-173 - - - G - - - Xylose isomerase domain protein TIM barrel
PHEDMDMH_00291 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHEDMDMH_00292 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PHEDMDMH_00293 3.89e-205 - - - I - - - alpha/beta hydrolase fold
PHEDMDMH_00294 7.3e-210 - - - I - - - alpha/beta hydrolase fold
PHEDMDMH_00295 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
PHEDMDMH_00296 2.17e-179 - - - K - - - Helix-turn-helix domain, rpiR family
PHEDMDMH_00297 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
PHEDMDMH_00298 1.83e-146 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
PHEDMDMH_00299 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHEDMDMH_00300 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHEDMDMH_00301 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
PHEDMDMH_00302 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
PHEDMDMH_00303 9.14e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
PHEDMDMH_00304 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHEDMDMH_00305 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHEDMDMH_00306 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
PHEDMDMH_00307 3.35e-305 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
PHEDMDMH_00308 1.02e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PHEDMDMH_00309 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PHEDMDMH_00310 1.74e-184 yxeH - - S - - - hydrolase
PHEDMDMH_00311 1.91e-235 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHEDMDMH_00313 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
PHEDMDMH_00314 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
PHEDMDMH_00315 1.08e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
PHEDMDMH_00316 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
PHEDMDMH_00317 4.12e-108 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
PHEDMDMH_00318 6.59e-75 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
PHEDMDMH_00319 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHEDMDMH_00320 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_00321 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_00322 4.05e-98 - - - - - - - -
PHEDMDMH_00323 4.15e-78 - - - - - - - -
PHEDMDMH_00324 1e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PHEDMDMH_00325 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
PHEDMDMH_00326 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PHEDMDMH_00327 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
PHEDMDMH_00328 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
PHEDMDMH_00329 1.49e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
PHEDMDMH_00330 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PHEDMDMH_00331 1.02e-102 uspA3 - - T - - - universal stress protein
PHEDMDMH_00332 5.88e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PHEDMDMH_00333 3.77e-24 - - - - - - - -
PHEDMDMH_00334 3.87e-56 - - - S - - - zinc-ribbon domain
PHEDMDMH_00335 8.5e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PHEDMDMH_00336 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
PHEDMDMH_00337 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
PHEDMDMH_00338 5.31e-285 - - - M - - - Glycosyl transferases group 1
PHEDMDMH_00339 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
PHEDMDMH_00340 4.74e-208 - - - S - - - Putative esterase
PHEDMDMH_00341 3.53e-169 - - - K - - - Transcriptional regulator
PHEDMDMH_00342 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHEDMDMH_00343 1.74e-178 - - - - - - - -
PHEDMDMH_00344 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHEDMDMH_00345 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
PHEDMDMH_00346 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
PHEDMDMH_00347 1.55e-79 - - - - - - - -
PHEDMDMH_00348 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PHEDMDMH_00349 2.97e-76 - - - - - - - -
PHEDMDMH_00350 0.0 yhdP - - S - - - Transporter associated domain
PHEDMDMH_00351 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
PHEDMDMH_00352 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
PHEDMDMH_00353 2.03e-271 yttB - - EGP - - - Major Facilitator
PHEDMDMH_00354 4.71e-81 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_00355 1.27e-219 - - - C - - - Zinc-binding dehydrogenase
PHEDMDMH_00356 4.71e-74 - - - S - - - SdpI/YhfL protein family
PHEDMDMH_00357 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHEDMDMH_00358 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
PHEDMDMH_00359 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHEDMDMH_00360 1.21e-183 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHEDMDMH_00361 3.59e-26 - - - - - - - -
PHEDMDMH_00362 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
PHEDMDMH_00363 5.73e-208 mleR - - K - - - LysR family
PHEDMDMH_00364 1.29e-148 - - - GM - - - NAD(P)H-binding
PHEDMDMH_00365 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
PHEDMDMH_00366 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PHEDMDMH_00367 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PHEDMDMH_00368 9.44e-219 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
PHEDMDMH_00369 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHEDMDMH_00370 1.55e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHEDMDMH_00371 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHEDMDMH_00372 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
PHEDMDMH_00373 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PHEDMDMH_00374 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHEDMDMH_00375 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PHEDMDMH_00376 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHEDMDMH_00377 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
PHEDMDMH_00378 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
PHEDMDMH_00379 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
PHEDMDMH_00380 2.24e-206 - - - GM - - - NmrA-like family
PHEDMDMH_00381 1.25e-199 - - - T - - - EAL domain
PHEDMDMH_00382 3.73e-121 - - - - - - - -
PHEDMDMH_00383 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
PHEDMDMH_00384 6.93e-162 - - - E - - - Methionine synthase
PHEDMDMH_00385 1.83e-278 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PHEDMDMH_00386 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PHEDMDMH_00387 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PHEDMDMH_00388 1.01e-156 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PHEDMDMH_00389 2.78e-61 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PHEDMDMH_00390 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHEDMDMH_00391 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHEDMDMH_00392 1.63e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHEDMDMH_00393 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHEDMDMH_00394 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PHEDMDMH_00395 5.8e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHEDMDMH_00396 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHEDMDMH_00397 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
PHEDMDMH_00398 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
PHEDMDMH_00399 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
PHEDMDMH_00400 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHEDMDMH_00401 3.44e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
PHEDMDMH_00402 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_00403 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
PHEDMDMH_00404 8.34e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00405 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PHEDMDMH_00406 4.76e-56 - - - - - - - -
PHEDMDMH_00407 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
PHEDMDMH_00408 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00409 3.41e-190 - - - - - - - -
PHEDMDMH_00410 2.7e-104 usp5 - - T - - - universal stress protein
PHEDMDMH_00411 1.08e-47 - - - - - - - -
PHEDMDMH_00412 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
PHEDMDMH_00413 1.76e-114 - - - - - - - -
PHEDMDMH_00414 4.87e-66 - - - - - - - -
PHEDMDMH_00415 4.79e-13 - - - - - - - -
PHEDMDMH_00416 8.32e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
PHEDMDMH_00417 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
PHEDMDMH_00418 1.02e-149 - - - - - - - -
PHEDMDMH_00419 1.21e-69 - - - - - - - -
PHEDMDMH_00421 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PHEDMDMH_00422 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
PHEDMDMH_00423 1.33e-185 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHEDMDMH_00424 4.72e-40 - - - S - - - Pentapeptide repeats (8 copies)
PHEDMDMH_00425 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
PHEDMDMH_00426 3.24e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
PHEDMDMH_00427 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
PHEDMDMH_00428 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
PHEDMDMH_00429 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
PHEDMDMH_00430 9.97e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
PHEDMDMH_00431 1.73e-291 - - - S - - - Sterol carrier protein domain
PHEDMDMH_00432 6.45e-146 - - - - - - - -
PHEDMDMH_00434 6.47e-147 is18 - - L - - - Integrase core domain
PHEDMDMH_00435 2.08e-60 - - - S - - - Phage derived protein Gp49-like (DUF891)
PHEDMDMH_00436 3.03e-49 - - - K - - - sequence-specific DNA binding
PHEDMDMH_00437 5.81e-88 - - - L - - - Transposase
PHEDMDMH_00438 7.6e-139 - - - L - - - Integrase
PHEDMDMH_00439 4.4e-138 - - - L - - - Integrase
PHEDMDMH_00440 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
PHEDMDMH_00442 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
PHEDMDMH_00443 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
PHEDMDMH_00447 5.21e-65 - - - S - - - Cupin 2, conserved barrel domain protein
PHEDMDMH_00448 1.38e-71 - - - S - - - Cupin domain
PHEDMDMH_00449 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
PHEDMDMH_00450 3.21e-145 - - - L - - - Helix-turn-helix domain
PHEDMDMH_00451 4.6e-218 - - - L ko:K07497 - ko00000 hmm pf00665
PHEDMDMH_00452 1.86e-246 ysdE - - P - - - Citrate transporter
PHEDMDMH_00453 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
PHEDMDMH_00454 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHEDMDMH_00455 2.4e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHEDMDMH_00456 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
PHEDMDMH_00457 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PHEDMDMH_00458 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHEDMDMH_00459 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHEDMDMH_00460 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
PHEDMDMH_00461 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
PHEDMDMH_00462 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
PHEDMDMH_00463 5.34e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PHEDMDMH_00464 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PHEDMDMH_00465 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHEDMDMH_00467 2.27e-197 - - - G - - - Peptidase_C39 like family
PHEDMDMH_00468 2.63e-217 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
PHEDMDMH_00469 2.43e-174 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
PHEDMDMH_00470 8.89e-218 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
PHEDMDMH_00471 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
PHEDMDMH_00472 0.0 levR - - K - - - Sigma-54 interaction domain
PHEDMDMH_00473 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PHEDMDMH_00474 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
PHEDMDMH_00475 3.67e-228 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHEDMDMH_00476 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
PHEDMDMH_00477 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
PHEDMDMH_00478 3.66e-184 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHEDMDMH_00479 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
PHEDMDMH_00480 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PHEDMDMH_00481 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
PHEDMDMH_00482 8.57e-227 - - - EG - - - EamA-like transporter family
PHEDMDMH_00483 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHEDMDMH_00484 1.12e-157 zmp2 - - O - - - Zinc-dependent metalloprotease
PHEDMDMH_00485 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
PHEDMDMH_00486 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHEDMDMH_00487 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
PHEDMDMH_00488 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
PHEDMDMH_00489 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHEDMDMH_00490 4.91e-265 yacL - - S - - - domain protein
PHEDMDMH_00491 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHEDMDMH_00492 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHEDMDMH_00493 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHEDMDMH_00494 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHEDMDMH_00495 3.4e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
PHEDMDMH_00496 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
PHEDMDMH_00497 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PHEDMDMH_00498 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHEDMDMH_00499 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PHEDMDMH_00500 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_00501 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHEDMDMH_00502 2.21e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHEDMDMH_00503 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHEDMDMH_00504 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHEDMDMH_00505 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
PHEDMDMH_00506 1.12e-84 - - - L - - - nuclease
PHEDMDMH_00507 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHEDMDMH_00508 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PHEDMDMH_00509 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHEDMDMH_00510 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHEDMDMH_00511 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
PHEDMDMH_00512 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PHEDMDMH_00513 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHEDMDMH_00514 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHEDMDMH_00515 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHEDMDMH_00516 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHEDMDMH_00517 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
PHEDMDMH_00518 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHEDMDMH_00519 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
PHEDMDMH_00520 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PHEDMDMH_00521 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
PHEDMDMH_00522 1.26e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHEDMDMH_00523 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
PHEDMDMH_00524 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PHEDMDMH_00525 2.09e-267 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
PHEDMDMH_00526 7.33e-142 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
PHEDMDMH_00527 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00528 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
PHEDMDMH_00529 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PHEDMDMH_00530 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
PHEDMDMH_00531 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
PHEDMDMH_00532 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
PHEDMDMH_00533 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PHEDMDMH_00534 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHEDMDMH_00535 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
PHEDMDMH_00536 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHEDMDMH_00537 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_00538 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHEDMDMH_00539 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHEDMDMH_00540 0.0 ydaO - - E - - - amino acid
PHEDMDMH_00541 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
PHEDMDMH_00542 3.8e-198 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PHEDMDMH_00543 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
PHEDMDMH_00544 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
PHEDMDMH_00545 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
PHEDMDMH_00546 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHEDMDMH_00547 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHEDMDMH_00548 3.41e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHEDMDMH_00549 8.15e-77 - - - - - - - -
PHEDMDMH_00550 2.09e-106 - - - - - - - -
PHEDMDMH_00551 5.21e-119 B4168_4126 - - L ko:K07493 - ko00000 Transposase
PHEDMDMH_00552 5.81e-191 - - - NU - - - Mycoplasma protein of unknown function, DUF285
PHEDMDMH_00553 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_00554 3.25e-96 - - - S - - - Bacterial protein of unknown function (DUF916)
PHEDMDMH_00555 3.29e-47 - - - S - - - Bacterial protein of unknown function (DUF916)
PHEDMDMH_00556 2.49e-57 - - - S - - - Bacterial protein of unknown function (DUF916)
PHEDMDMH_00557 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHEDMDMH_00558 6.41e-84 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_00559 1.5e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PHEDMDMH_00560 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
PHEDMDMH_00561 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_00562 2.28e-200 - - - GM - - - NmrA-like family
PHEDMDMH_00563 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00564 7.82e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHEDMDMH_00565 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHEDMDMH_00566 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PHEDMDMH_00567 3.35e-217 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PHEDMDMH_00568 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00569 0.0 yfjF - - U - - - Sugar (and other) transporter
PHEDMDMH_00570 1.33e-227 ydhF - - S - - - Aldo keto reductase
PHEDMDMH_00571 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
PHEDMDMH_00572 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
PHEDMDMH_00573 1.66e-125 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00574 3.27e-170 - - - S - - - KR domain
PHEDMDMH_00575 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
PHEDMDMH_00576 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
PHEDMDMH_00577 4.41e-54 - - - M - - - Glycosyl hydrolases family 25
PHEDMDMH_00578 0.0 - - - M - - - Glycosyl hydrolases family 25
PHEDMDMH_00579 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PHEDMDMH_00580 6.24e-215 - - - GM - - - NmrA-like family
PHEDMDMH_00581 1.03e-126 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00583 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHEDMDMH_00584 1.27e-170 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PHEDMDMH_00585 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PHEDMDMH_00586 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
PHEDMDMH_00587 1.81e-272 - - - EGP - - - Major Facilitator
PHEDMDMH_00588 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
PHEDMDMH_00589 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
PHEDMDMH_00590 4.13e-157 - - - - - - - -
PHEDMDMH_00591 4.3e-302 - - - NU - - - Mycoplasma protein of unknown function, DUF285
PHEDMDMH_00592 1.47e-83 - - - - - - - -
PHEDMDMH_00593 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_00594 7.66e-237 ynjC - - S - - - Cell surface protein
PHEDMDMH_00595 3.89e-148 - - - S - - - GyrI-like small molecule binding domain
PHEDMDMH_00596 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
PHEDMDMH_00597 1.55e-224 - - - C - - - Alcohol dehydrogenase GroES-like domain
PHEDMDMH_00598 3.48e-136 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_00599 5.14e-246 - - - S - - - Cell surface protein
PHEDMDMH_00600 2.69e-99 - - - - - - - -
PHEDMDMH_00601 0.0 - - - - - - - -
PHEDMDMH_00602 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHEDMDMH_00603 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
PHEDMDMH_00604 2.81e-181 - - - K - - - Helix-turn-helix domain
PHEDMDMH_00605 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PHEDMDMH_00606 1.36e-84 - - - S - - - Cupredoxin-like domain
PHEDMDMH_00607 1.49e-58 - - - S - - - Cupredoxin-like domain
PHEDMDMH_00608 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PHEDMDMH_00609 1.37e-271 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
PHEDMDMH_00610 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
PHEDMDMH_00611 1.67e-86 lysM - - M - - - LysM domain
PHEDMDMH_00612 0.0 - - - E - - - Amino Acid
PHEDMDMH_00613 2.47e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
PHEDMDMH_00614 1.97e-92 - - - - - - - -
PHEDMDMH_00616 2.96e-209 yhxD - - IQ - - - KR domain
PHEDMDMH_00617 7.29e-287 amd - - E - - - Peptidase family M20/M25/M40
PHEDMDMH_00618 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00619 1.45e-97 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_00620 3.5e-308 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_00621 2.31e-277 - - - - - - - -
PHEDMDMH_00622 2.4e-151 - - - GM - - - NAD(P)H-binding
PHEDMDMH_00623 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
PHEDMDMH_00624 3.55e-79 - - - I - - - sulfurtransferase activity
PHEDMDMH_00625 6.7e-102 yphH - - S - - - Cupin domain
PHEDMDMH_00626 1.37e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
PHEDMDMH_00627 1.77e-150 - - - GM - - - NAD(P)H-binding
PHEDMDMH_00628 7.62e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
PHEDMDMH_00629 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_00630 5.26e-96 - - - - - - - -
PHEDMDMH_00631 1.66e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
PHEDMDMH_00632 1.56e-56 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_00633 1e-98 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
PHEDMDMH_00634 6.61e-77 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_00636 3.15e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
PHEDMDMH_00637 3.26e-58 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PHEDMDMH_00638 9.99e-19 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
PHEDMDMH_00639 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PHEDMDMH_00640 2.57e-116 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHEDMDMH_00641 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PHEDMDMH_00642 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_00643 1.93e-31 plnF - - - - - - -
PHEDMDMH_00644 2.59e-19 - - - - - - - -
PHEDMDMH_00645 1.65e-199 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHEDMDMH_00646 3.13e-278 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHEDMDMH_00647 1.17e-306 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
PHEDMDMH_00648 1.83e-140 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_00649 8.02e-152 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_00650 1.86e-143 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_00651 1.59e-145 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_00652 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
PHEDMDMH_00653 0.0 - - - L - - - DNA helicase
PHEDMDMH_00654 5.87e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
PHEDMDMH_00655 2.35e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PHEDMDMH_00656 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
PHEDMDMH_00657 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_00658 9.68e-34 - - - - - - - -
PHEDMDMH_00659 1.69e-97 - - - S - - - Domain of unknown function (DUF3284)
PHEDMDMH_00660 5.9e-46 - - - - - - - -
PHEDMDMH_00661 1.6e-77 chpA - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHEDMDMH_00662 1.2e-243 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHEDMDMH_00663 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
PHEDMDMH_00664 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
PHEDMDMH_00665 4.65e-229 - - - - - - - -
PHEDMDMH_00666 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
PHEDMDMH_00667 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
PHEDMDMH_00668 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
PHEDMDMH_00669 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHEDMDMH_00670 1.81e-273 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
PHEDMDMH_00671 5.1e-106 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
PHEDMDMH_00673 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
PHEDMDMH_00674 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHEDMDMH_00675 1.19e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHEDMDMH_00676 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
PHEDMDMH_00677 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PHEDMDMH_00678 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
PHEDMDMH_00679 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PHEDMDMH_00680 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
PHEDMDMH_00681 2.95e-57 - - - S - - - ankyrin repeats
PHEDMDMH_00682 5.3e-49 - - - - - - - -
PHEDMDMH_00683 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PHEDMDMH_00684 5.78e-292 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHEDMDMH_00685 7.44e-192 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
PHEDMDMH_00686 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHEDMDMH_00687 2.82e-236 - - - S - - - DUF218 domain
PHEDMDMH_00688 2.49e-178 - - - - - - - -
PHEDMDMH_00689 1.45e-191 yxeH - - S - - - hydrolase
PHEDMDMH_00690 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
PHEDMDMH_00691 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
PHEDMDMH_00692 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
PHEDMDMH_00693 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHEDMDMH_00694 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHEDMDMH_00695 8.29e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHEDMDMH_00696 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
PHEDMDMH_00697 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
PHEDMDMH_00698 9.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PHEDMDMH_00699 6.59e-170 - - - S - - - YheO-like PAS domain
PHEDMDMH_00700 4.01e-36 - - - - - - - -
PHEDMDMH_00701 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHEDMDMH_00702 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PHEDMDMH_00703 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PHEDMDMH_00704 1.49e-273 - - - J - - - translation release factor activity
PHEDMDMH_00705 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
PHEDMDMH_00706 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
PHEDMDMH_00707 1.78e-191 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PHEDMDMH_00708 1.84e-189 - - - - - - - -
PHEDMDMH_00709 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHEDMDMH_00710 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHEDMDMH_00711 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHEDMDMH_00712 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHEDMDMH_00713 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
PHEDMDMH_00714 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
PHEDMDMH_00715 1.13e-247 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_00716 7.44e-203 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_00717 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHEDMDMH_00718 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
PHEDMDMH_00719 3.11e-41 - - - D - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHEDMDMH_00722 0.0 - - - S - - - ABC transporter, ATP-binding protein
PHEDMDMH_00723 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
PHEDMDMH_00724 3.9e-105 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHEDMDMH_00725 9.2e-62 - - - - - - - -
PHEDMDMH_00726 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
PHEDMDMH_00727 4.37e-241 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHEDMDMH_00728 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
PHEDMDMH_00729 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
PHEDMDMH_00730 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PHEDMDMH_00731 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
PHEDMDMH_00732 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_00733 7.03e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHEDMDMH_00734 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00735 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
PHEDMDMH_00736 9.51e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
PHEDMDMH_00737 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
PHEDMDMH_00738 7.09e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
PHEDMDMH_00739 4.48e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PHEDMDMH_00740 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
PHEDMDMH_00741 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PHEDMDMH_00742 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PHEDMDMH_00743 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PHEDMDMH_00744 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PHEDMDMH_00745 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PHEDMDMH_00746 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PHEDMDMH_00747 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PHEDMDMH_00748 4.44e-273 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PHEDMDMH_00749 3.2e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
PHEDMDMH_00750 3.72e-283 ysaA - - V - - - RDD family
PHEDMDMH_00751 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
PHEDMDMH_00752 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
PHEDMDMH_00753 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
PHEDMDMH_00754 2.49e-190 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_00755 4.54e-126 - - - J - - - glyoxalase III activity
PHEDMDMH_00756 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHEDMDMH_00757 9.88e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHEDMDMH_00758 1.45e-46 - - - - - - - -
PHEDMDMH_00759 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
PHEDMDMH_00760 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
PHEDMDMH_00761 0.0 - - - M - - - domain protein
PHEDMDMH_00762 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
PHEDMDMH_00763 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHEDMDMH_00764 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
PHEDMDMH_00765 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PHEDMDMH_00766 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_00767 6.93e-248 - - - S - - - domain, Protein
PHEDMDMH_00768 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
PHEDMDMH_00769 2.57e-128 - - - C - - - Nitroreductase family
PHEDMDMH_00770 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
PHEDMDMH_00771 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHEDMDMH_00772 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHEDMDMH_00773 1.48e-201 ccpB - - K - - - lacI family
PHEDMDMH_00774 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
PHEDMDMH_00775 9.95e-92 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHEDMDMH_00776 2.02e-217 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PHEDMDMH_00777 1.55e-49 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHEDMDMH_00778 9.51e-49 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHEDMDMH_00779 8.97e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
PHEDMDMH_00780 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
PHEDMDMH_00781 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHEDMDMH_00782 2.69e-138 pncA - - Q - - - Isochorismatase family
PHEDMDMH_00783 2.66e-172 - - - - - - - -
PHEDMDMH_00784 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_00785 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
PHEDMDMH_00786 7.2e-61 - - - S - - - Enterocin A Immunity
PHEDMDMH_00787 4.62e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
PHEDMDMH_00788 0.0 pepF2 - - E - - - Oligopeptidase F
PHEDMDMH_00789 1.4e-95 - - - K - - - Transcriptional regulator
PHEDMDMH_00790 2.64e-210 - - - - - - - -
PHEDMDMH_00792 3.68e-77 - - - - - - - -
PHEDMDMH_00793 4.83e-64 - - - - - - - -
PHEDMDMH_00794 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PHEDMDMH_00795 5.82e-89 - - - - - - - -
PHEDMDMH_00796 1.97e-185 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
PHEDMDMH_00797 9.89e-74 ytpP - - CO - - - Thioredoxin
PHEDMDMH_00798 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
PHEDMDMH_00799 3.89e-62 - - - - - - - -
PHEDMDMH_00800 1.57e-71 - - - - - - - -
PHEDMDMH_00801 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
PHEDMDMH_00802 8.19e-49 - - - L - - - Transposase DDE domain
PHEDMDMH_00803 1.04e-56 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
PHEDMDMH_00804 0.0 FbpA - - K - - - Fibronectin-binding protein
PHEDMDMH_00805 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHEDMDMH_00806 4.87e-205 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00807 1.27e-115 - - - F - - - NUDIX domain
PHEDMDMH_00809 3.42e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
PHEDMDMH_00810 2.08e-92 - - - S - - - LuxR family transcriptional regulator
PHEDMDMH_00811 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
PHEDMDMH_00813 7.75e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PHEDMDMH_00814 2.01e-145 - - - G - - - Phosphoglycerate mutase family
PHEDMDMH_00815 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
PHEDMDMH_00816 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
PHEDMDMH_00817 1.56e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHEDMDMH_00818 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PHEDMDMH_00819 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHEDMDMH_00820 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
PHEDMDMH_00821 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
PHEDMDMH_00822 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
PHEDMDMH_00823 8.53e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
PHEDMDMH_00824 3.03e-186 - - - S - - - hydrolase activity, acting on ester bonds
PHEDMDMH_00825 6.79e-249 - - - - - - - -
PHEDMDMH_00826 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHEDMDMH_00827 4.35e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
PHEDMDMH_00828 1.38e-232 - - - V - - - LD-carboxypeptidase
PHEDMDMH_00829 1.23e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
PHEDMDMH_00830 6.74e-101 - - - K - - - Acetyltransferase (GNAT) domain
PHEDMDMH_00831 3.46e-267 mccF - - V - - - LD-carboxypeptidase
PHEDMDMH_00832 9.63e-307 - - - M - - - Glycosyltransferase, group 2 family protein
PHEDMDMH_00833 9.19e-95 - - - S - - - SnoaL-like domain
PHEDMDMH_00834 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PHEDMDMH_00835 6.32e-309 - - - P - - - Major Facilitator Superfamily
PHEDMDMH_00836 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_00837 5.84e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PHEDMDMH_00839 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHEDMDMH_00840 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
PHEDMDMH_00841 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHEDMDMH_00842 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
PHEDMDMH_00843 8.03e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PHEDMDMH_00844 8.06e-234 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHEDMDMH_00845 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_00846 5.32e-109 - - - T - - - Universal stress protein family
PHEDMDMH_00847 1.58e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PHEDMDMH_00848 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00849 1.34e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHEDMDMH_00851 3.25e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
PHEDMDMH_00852 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
PHEDMDMH_00853 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PHEDMDMH_00854 2.53e-107 ypmB - - S - - - protein conserved in bacteria
PHEDMDMH_00855 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PHEDMDMH_00856 1.21e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
PHEDMDMH_00857 2.22e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
PHEDMDMH_00858 7.22e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
PHEDMDMH_00859 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHEDMDMH_00860 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
PHEDMDMH_00861 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
PHEDMDMH_00862 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
PHEDMDMH_00863 1.38e-156 - - - S - - - Domain of unknown function (DUF4767)
PHEDMDMH_00864 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
PHEDMDMH_00865 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
PHEDMDMH_00866 0.0 - - - E ko:K03294 - ko00000 Amino Acid
PHEDMDMH_00867 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PHEDMDMH_00868 3.23e-58 - - - - - - - -
PHEDMDMH_00869 1.25e-66 - - - - - - - -
PHEDMDMH_00870 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
PHEDMDMH_00871 1.48e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
PHEDMDMH_00872 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHEDMDMH_00873 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
PHEDMDMH_00874 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHEDMDMH_00875 1.06e-53 - - - - - - - -
PHEDMDMH_00876 4e-40 - - - S - - - CsbD-like
PHEDMDMH_00877 2.22e-55 - - - S - - - transglycosylase associated protein
PHEDMDMH_00878 5.79e-21 - - - - - - - -
PHEDMDMH_00879 1.51e-48 - - - - - - - -
PHEDMDMH_00880 2.43e-87 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
PHEDMDMH_00881 2.59e-228 - - - - - - - -
PHEDMDMH_00882 2.11e-104 - - - - - - - -
PHEDMDMH_00883 3.47e-47 - - - - - - - -
PHEDMDMH_00884 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
PHEDMDMH_00885 2.03e-75 - - - - - - - -
PHEDMDMH_00886 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHEDMDMH_00887 1.26e-100 - - - S ko:K02348 - ko00000 GNAT family
PHEDMDMH_00888 1.24e-99 - - - K - - - Transcriptional regulator
PHEDMDMH_00889 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PHEDMDMH_00890 2.18e-53 - - - - - - - -
PHEDMDMH_00891 3.07e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_00892 1.31e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00893 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00894 1.46e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHEDMDMH_00895 1.5e-124 - - - K - - - Cupin domain
PHEDMDMH_00896 8.08e-110 - - - S - - - ASCH
PHEDMDMH_00897 1.88e-111 - - - K - - - GNAT family
PHEDMDMH_00898 1.19e-114 - - - K - - - acetyltransferase
PHEDMDMH_00899 2.06e-30 - - - - - - - -
PHEDMDMH_00900 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PHEDMDMH_00901 7.53e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_00902 1.47e-241 - - - - - - - -
PHEDMDMH_00903 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
PHEDMDMH_00904 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
PHEDMDMH_00906 5.55e-304 xylP1 - - G - - - MFS/sugar transport protein
PHEDMDMH_00907 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
PHEDMDMH_00908 7.28e-42 - - - - - - - -
PHEDMDMH_00909 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHEDMDMH_00910 6.4e-54 - - - - - - - -
PHEDMDMH_00911 7.31e-122 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PHEDMDMH_00912 5.83e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHEDMDMH_00913 4.03e-81 - - - S - - - CHY zinc finger
PHEDMDMH_00914 2.58e-283 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHEDMDMH_00915 1.1e-280 - - - - - - - -
PHEDMDMH_00916 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
PHEDMDMH_00917 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PHEDMDMH_00918 6.53e-58 - - - - - - - -
PHEDMDMH_00919 4.63e-119 - - - K - - - Transcriptional regulator PadR-like family
PHEDMDMH_00920 0.0 - - - P - - - Major Facilitator Superfamily
PHEDMDMH_00921 1.66e-305 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
PHEDMDMH_00922 7.39e-226 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
PHEDMDMH_00923 8.95e-60 - - - - - - - -
PHEDMDMH_00924 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
PHEDMDMH_00925 6.87e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PHEDMDMH_00926 0.0 sufI - - Q - - - Multicopper oxidase
PHEDMDMH_00927 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
PHEDMDMH_00928 5.33e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
PHEDMDMH_00929 3.25e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
PHEDMDMH_00930 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
PHEDMDMH_00931 2.16e-103 - - - - - - - -
PHEDMDMH_00932 3.45e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHEDMDMH_00933 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
PHEDMDMH_00934 2.42e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_00935 4.06e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
PHEDMDMH_00936 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHEDMDMH_00937 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00938 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
PHEDMDMH_00939 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHEDMDMH_00940 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
PHEDMDMH_00941 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHEDMDMH_00942 0.0 - - - M - - - domain protein
PHEDMDMH_00943 8.33e-90 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
PHEDMDMH_00944 1.82e-34 - - - S - - - Immunity protein 74
PHEDMDMH_00945 5.01e-226 - - - - - - - -
PHEDMDMH_00946 1.24e-11 - - - S - - - Immunity protein 22
PHEDMDMH_00947 5.89e-131 - - - S - - - ankyrin repeats
PHEDMDMH_00948 1.3e-49 - - - - - - - -
PHEDMDMH_00949 8.53e-28 - - - - - - - -
PHEDMDMH_00950 5.52e-64 - - - U - - - nuclease activity
PHEDMDMH_00951 5.89e-90 - - - - - - - -
PHEDMDMH_00952 1.32e-29 - - - - - - - -
PHEDMDMH_00954 5.87e-22 - - - - - - - -
PHEDMDMH_00955 3.27e-81 - - - - - - - -
PHEDMDMH_00956 8.02e-110 - - - S - - - Pfam:DUF3816
PHEDMDMH_00957 3.47e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHEDMDMH_00958 1.27e-143 - - - - - - - -
PHEDMDMH_00959 1.08e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHEDMDMH_00960 9.06e-184 - - - S - - - Peptidase_C39 like family
PHEDMDMH_00961 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
PHEDMDMH_00962 1.95e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PHEDMDMH_00963 3.82e-188 - - - KT - - - helix_turn_helix, mercury resistance
PHEDMDMH_00964 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PHEDMDMH_00965 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
PHEDMDMH_00966 1.4e-239 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00967 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00968 2.27e-116 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
PHEDMDMH_00969 8.13e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
PHEDMDMH_00970 1.39e-124 ywjB - - H - - - RibD C-terminal domain
PHEDMDMH_00971 8.02e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHEDMDMH_00972 9.01e-155 - - - S - - - Membrane
PHEDMDMH_00973 1.42e-197 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
PHEDMDMH_00974 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
PHEDMDMH_00975 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
PHEDMDMH_00976 1.99e-160 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PHEDMDMH_00977 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
PHEDMDMH_00978 2.33e-103 - - - S - - - Domain of unknown function (DUF4811)
PHEDMDMH_00979 7.96e-127 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHEDMDMH_00980 4.38e-222 - - - S - - - Conserved hypothetical protein 698
PHEDMDMH_00981 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
PHEDMDMH_00982 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
PHEDMDMH_00983 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHEDMDMH_00985 9.92e-88 - - - M - - - LysM domain
PHEDMDMH_00986 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
PHEDMDMH_00987 9.97e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00988 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHEDMDMH_00989 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_00990 4.72e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PHEDMDMH_00991 4.77e-100 yphH - - S - - - Cupin domain
PHEDMDMH_00992 5.19e-103 - - - K - - - transcriptional regulator, MerR family
PHEDMDMH_00993 1.46e-299 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
PHEDMDMH_00994 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
PHEDMDMH_00995 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_00997 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHEDMDMH_00998 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
PHEDMDMH_00999 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PHEDMDMH_01001 4.86e-111 - - - - - - - -
PHEDMDMH_01002 1.04e-110 yvbK - - K - - - GNAT family
PHEDMDMH_01003 9.76e-50 - - - - - - - -
PHEDMDMH_01004 2.81e-64 - - - - - - - -
PHEDMDMH_01005 7.44e-143 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
PHEDMDMH_01006 6.09e-83 - - - S - - - Domain of unknown function (DUF4440)
PHEDMDMH_01007 6.13e-200 - - - K - - - LysR substrate binding domain
PHEDMDMH_01008 1.52e-135 - - - GM - - - NAD(P)H-binding
PHEDMDMH_01009 1.66e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PHEDMDMH_01010 3.38e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PHEDMDMH_01011 1.28e-45 - - - - - - - -
PHEDMDMH_01012 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
PHEDMDMH_01013 2.09e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
PHEDMDMH_01014 5.89e-161 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PHEDMDMH_01015 2.31e-79 - - - - - - - -
PHEDMDMH_01016 5.29e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
PHEDMDMH_01017 2.33e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
PHEDMDMH_01018 1.07e-131 - - - M - - - Protein of unknown function (DUF3737)
PHEDMDMH_01019 1.8e-249 - - - C - - - Aldo/keto reductase family
PHEDMDMH_01021 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_01022 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_01023 4.51e-314 - - - EGP - - - Major Facilitator
PHEDMDMH_01024 7.21e-35 - - - - - - - -
PHEDMDMH_01025 2.55e-65 - - - - - - - -
PHEDMDMH_01026 4.86e-84 - - - S - - - Protein of unknown function (DUF1398)
PHEDMDMH_01027 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
PHEDMDMH_01028 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
PHEDMDMH_01029 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
PHEDMDMH_01030 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
PHEDMDMH_01031 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
PHEDMDMH_01032 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
PHEDMDMH_01033 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PHEDMDMH_01034 8.84e-182 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
PHEDMDMH_01036 1.12e-208 yvgN - - C - - - Aldo keto reductase
PHEDMDMH_01037 2.57e-171 - - - S - - - Putative threonine/serine exporter
PHEDMDMH_01038 1.7e-101 - - - S - - - Threonine/Serine exporter, ThrE
PHEDMDMH_01039 1.5e-56 - - - S - - - Protein of unknown function (DUF1093)
PHEDMDMH_01040 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PHEDMDMH_01041 5.94e-118 ymdB - - S - - - Macro domain protein
PHEDMDMH_01042 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
PHEDMDMH_01043 1.58e-66 - - - - - - - -
PHEDMDMH_01044 1.39e-211 - - - S - - - Protein of unknown function (DUF1002)
PHEDMDMH_01045 0.0 - - - - - - - -
PHEDMDMH_01046 6.48e-244 - - - S - - - Bacterial protein of unknown function (DUF916)
PHEDMDMH_01047 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_01048 2.74e-175 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
PHEDMDMH_01049 5.33e-114 - - - K - - - Winged helix DNA-binding domain
PHEDMDMH_01050 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_01051 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
PHEDMDMH_01052 4.45e-38 - - - - - - - -
PHEDMDMH_01053 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
PHEDMDMH_01054 2.75e-96 - - - M - - - PFAM NLP P60 protein
PHEDMDMH_01055 6.18e-71 - - - - - - - -
PHEDMDMH_01056 5.77e-81 - - - - - - - -
PHEDMDMH_01058 9.39e-84 - - - - - - - -
PHEDMDMH_01060 1.12e-134 - - - K - - - transcriptional regulator
PHEDMDMH_01061 7.46e-35 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
PHEDMDMH_01062 2.07e-154 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
PHEDMDMH_01063 3.42e-174 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PHEDMDMH_01064 1.5e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
PHEDMDMH_01065 1.98e-232 - - - E - - - GDSL-like Lipase/Acylhydrolase family
PHEDMDMH_01066 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
PHEDMDMH_01067 2.71e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHEDMDMH_01068 2.34e-72 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
PHEDMDMH_01069 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
PHEDMDMH_01070 1.01e-26 - - - - - - - -
PHEDMDMH_01071 1.74e-125 dpsB - - P - - - Belongs to the Dps family
PHEDMDMH_01072 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
PHEDMDMH_01073 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
PHEDMDMH_01074 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
PHEDMDMH_01075 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PHEDMDMH_01076 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
PHEDMDMH_01077 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
PHEDMDMH_01078 1.83e-235 - - - S - - - Cell surface protein
PHEDMDMH_01079 1.44e-158 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_01080 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_01081 7.83e-60 - - - - - - - -
PHEDMDMH_01082 8.19e-134 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
PHEDMDMH_01083 1.03e-65 - - - - - - - -
PHEDMDMH_01084 4.67e-316 - - - S - - - Putative metallopeptidase domain
PHEDMDMH_01085 3.31e-282 - - - S - - - associated with various cellular activities
PHEDMDMH_01086 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHEDMDMH_01087 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
PHEDMDMH_01088 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PHEDMDMH_01089 4.67e-250 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
PHEDMDMH_01090 9.54e-65 - - - K - - - sequence-specific DNA binding
PHEDMDMH_01095 1.38e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHEDMDMH_01096 2.05e-231 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHEDMDMH_01097 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PHEDMDMH_01098 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHEDMDMH_01099 1.24e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PHEDMDMH_01100 3.06e-205 mleR2 - - K - - - LysR family transcriptional regulator
PHEDMDMH_01101 6.5e-215 mleR - - K - - - LysR family
PHEDMDMH_01102 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
PHEDMDMH_01103 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
PHEDMDMH_01104 0.0 - - - E ko:K03294 - ko00000 Amino Acid
PHEDMDMH_01105 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
PHEDMDMH_01106 6.07e-33 - - - - - - - -
PHEDMDMH_01107 0.0 - - - S ko:K06889 - ko00000 Alpha beta
PHEDMDMH_01108 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
PHEDMDMH_01109 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
PHEDMDMH_01110 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PHEDMDMH_01111 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PHEDMDMH_01112 1.02e-121 - - - S - - - L,D-transpeptidase catalytic domain
PHEDMDMH_01113 1.24e-66 - - - S - - - protein conserved in bacteria
PHEDMDMH_01114 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PHEDMDMH_01115 2.84e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
PHEDMDMH_01116 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
PHEDMDMH_01117 3.41e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
PHEDMDMH_01118 8.19e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHEDMDMH_01119 1.13e-120 yebE - - S - - - UPF0316 protein
PHEDMDMH_01120 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PHEDMDMH_01121 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PHEDMDMH_01122 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHEDMDMH_01123 3.86e-262 camS - - S - - - sex pheromone
PHEDMDMH_01124 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHEDMDMH_01125 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHEDMDMH_01126 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHEDMDMH_01127 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
PHEDMDMH_01128 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHEDMDMH_01129 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_01130 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
PHEDMDMH_01131 2.75e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_01132 1.94e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_01133 9.33e-195 gntR - - K - - - rpiR family
PHEDMDMH_01134 1.67e-177 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
PHEDMDMH_01135 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
PHEDMDMH_01136 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
PHEDMDMH_01137 1.94e-245 mocA - - S - - - Oxidoreductase
PHEDMDMH_01138 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
PHEDMDMH_01140 3.93e-99 - - - T - - - Universal stress protein family
PHEDMDMH_01141 5.45e-314 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_01142 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_01144 7.62e-97 - - - - - - - -
PHEDMDMH_01145 2.9e-139 - - - - - - - -
PHEDMDMH_01147 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_01148 1.31e-29 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_01150 1.77e-145 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
PHEDMDMH_01151 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
PHEDMDMH_01152 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
PHEDMDMH_01153 8.81e-205 - - - S - - - Alpha beta hydrolase
PHEDMDMH_01154 1.39e-143 - - - GM - - - NmrA-like family
PHEDMDMH_01155 1.74e-101 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
PHEDMDMH_01156 5.72e-207 - - - K - - - Transcriptional regulator
PHEDMDMH_01157 3.78e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
PHEDMDMH_01159 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHEDMDMH_01160 1.04e-137 - - - - - - - -
PHEDMDMH_01161 4.94e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_01162 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PHEDMDMH_01163 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHEDMDMH_01164 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHEDMDMH_01165 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PHEDMDMH_01166 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PHEDMDMH_01167 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PHEDMDMH_01168 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHEDMDMH_01169 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PHEDMDMH_01170 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHEDMDMH_01171 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
PHEDMDMH_01172 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
PHEDMDMH_01173 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PHEDMDMH_01174 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PHEDMDMH_01175 3.5e-164 - - - C - - - Enoyl-(Acyl carrier protein) reductase
PHEDMDMH_01176 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PHEDMDMH_01177 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHEDMDMH_01178 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHEDMDMH_01179 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHEDMDMH_01180 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHEDMDMH_01181 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PHEDMDMH_01182 4.01e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
PHEDMDMH_01183 2.97e-210 - - - G - - - Fructosamine kinase
PHEDMDMH_01184 2.43e-150 yjcF - - J - - - HAD-hyrolase-like
PHEDMDMH_01185 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHEDMDMH_01186 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHEDMDMH_01187 2.56e-76 - - - - - - - -
PHEDMDMH_01188 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PHEDMDMH_01189 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
PHEDMDMH_01190 5.28e-146 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PHEDMDMH_01191 4.78e-65 - - - - - - - -
PHEDMDMH_01192 1.73e-67 - - - - - - - -
PHEDMDMH_01195 1.01e-158 int7 - - L - - - Belongs to the 'phage' integrase family
PHEDMDMH_01196 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHEDMDMH_01197 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHEDMDMH_01198 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHEDMDMH_01199 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
PHEDMDMH_01200 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHEDMDMH_01201 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
PHEDMDMH_01202 8.49e-266 pbpX2 - - V - - - Beta-lactamase
PHEDMDMH_01203 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHEDMDMH_01204 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PHEDMDMH_01205 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHEDMDMH_01206 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHEDMDMH_01207 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
PHEDMDMH_01208 1.53e-241 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PHEDMDMH_01209 8.94e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHEDMDMH_01210 2.41e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PHEDMDMH_01211 1.47e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PHEDMDMH_01212 1.24e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PHEDMDMH_01213 1.63e-121 - - - - - - - -
PHEDMDMH_01214 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PHEDMDMH_01215 0.0 - - - G - - - Major Facilitator
PHEDMDMH_01216 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHEDMDMH_01217 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHEDMDMH_01218 3.28e-63 ylxQ - - J - - - ribosomal protein
PHEDMDMH_01219 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
PHEDMDMH_01220 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PHEDMDMH_01221 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PHEDMDMH_01222 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHEDMDMH_01223 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHEDMDMH_01224 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PHEDMDMH_01225 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PHEDMDMH_01226 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHEDMDMH_01227 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHEDMDMH_01228 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PHEDMDMH_01229 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHEDMDMH_01230 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PHEDMDMH_01231 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
PHEDMDMH_01232 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHEDMDMH_01233 5.67e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
PHEDMDMH_01234 2.11e-171 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
PHEDMDMH_01235 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
PHEDMDMH_01236 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
PHEDMDMH_01237 7.68e-48 ynzC - - S - - - UPF0291 protein
PHEDMDMH_01238 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHEDMDMH_01239 7.8e-123 - - - - - - - -
PHEDMDMH_01240 1.56e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
PHEDMDMH_01241 1.38e-98 - - - - - - - -
PHEDMDMH_01242 3.81e-87 - - - - - - - -
PHEDMDMH_01243 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
PHEDMDMH_01244 2.19e-131 - - - L - - - Helix-turn-helix domain
PHEDMDMH_01245 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
PHEDMDMH_01246 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHEDMDMH_01247 3.64e-144 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_01248 3.06e-234 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_01249 1.96e-293 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
PHEDMDMH_01251 3.33e-56 - - - S - - - Bacteriophage holin
PHEDMDMH_01252 1.46e-46 - - - S - - - Haemolysin XhlA
PHEDMDMH_01253 2.31e-257 - - - M - - - Glycosyl hydrolases family 25
PHEDMDMH_01254 9.89e-33 - - - - - - - -
PHEDMDMH_01255 3.51e-99 - - - - - - - -
PHEDMDMH_01258 3.47e-186 - - - - - - - -
PHEDMDMH_01259 0.0 - - - S - - - Phage minor structural protein
PHEDMDMH_01260 0.0 - - - S - - - Phage tail protein
PHEDMDMH_01261 5.57e-241 - - - L - - - Phage tail tape measure protein TP901
PHEDMDMH_01262 0.0 - - - D - - - domain protein
PHEDMDMH_01263 5.71e-33 - - - - - - - -
PHEDMDMH_01264 1.58e-74 - - - S - - - Phage tail assembly chaperone proteins, TAC
PHEDMDMH_01265 1.59e-135 - - - S - - - Phage tail tube protein
PHEDMDMH_01266 7.47e-74 - - - S - - - Protein of unknown function (DUF806)
PHEDMDMH_01267 3.74e-85 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PHEDMDMH_01268 6.96e-76 - - - S - - - Phage head-tail joining protein
PHEDMDMH_01269 1.97e-66 - - - S - - - Phage gp6-like head-tail connector protein
PHEDMDMH_01270 9.11e-266 - - - S - - - Phage capsid family
PHEDMDMH_01271 5.38e-161 - - - S - - - Clp protease
PHEDMDMH_01272 8.48e-285 - - - S - - - Phage portal protein
PHEDMDMH_01273 3.74e-32 - - - S - - - Protein of unknown function (DUF1056)
PHEDMDMH_01274 0.0 - - - S - - - Phage Terminase
PHEDMDMH_01275 1.29e-102 - - - S - - - Phage terminase, small subunit
PHEDMDMH_01276 5.72e-117 - - - L - - - HNH nucleases
PHEDMDMH_01279 4.83e-47 - - - S - - - Transcriptional regulator, RinA family
PHEDMDMH_01282 8.09e-235 - - - - - - - -
PHEDMDMH_01284 2.21e-50 - - - S - - - YopX protein
PHEDMDMH_01286 2.1e-17 - - - - - - - -
PHEDMDMH_01287 4.83e-61 - - - - - - - -
PHEDMDMH_01289 2.4e-186 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
PHEDMDMH_01290 7.13e-42 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
PHEDMDMH_01293 1.87e-24 - - - - - - - -
PHEDMDMH_01301 6.04e-87 - - - S - - - DNA binding
PHEDMDMH_01303 2.9e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
PHEDMDMH_01306 4.16e-51 - - - S - - - Membrane
PHEDMDMH_01312 8.67e-75 int3 - - L - - - Belongs to the 'phage' integrase family
PHEDMDMH_01313 1.75e-43 - - - - - - - -
PHEDMDMH_01314 6.34e-178 - - - Q - - - Methyltransferase
PHEDMDMH_01315 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
PHEDMDMH_01316 2.75e-268 - - - EGP - - - Major facilitator Superfamily
PHEDMDMH_01317 3.58e-129 - - - K - - - Helix-turn-helix domain
PHEDMDMH_01318 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHEDMDMH_01319 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PHEDMDMH_01320 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
PHEDMDMH_01321 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_01322 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHEDMDMH_01323 6.62e-62 - - - - - - - -
PHEDMDMH_01324 1.28e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHEDMDMH_01325 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
PHEDMDMH_01326 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHEDMDMH_01327 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
PHEDMDMH_01328 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
PHEDMDMH_01329 4.34e-220 cps4J - - S - - - MatE
PHEDMDMH_01330 1.19e-88 cps4J - - S - - - MatE
PHEDMDMH_01331 3.4e-228 cps4I - - M - - - Glycosyltransferase like family 2
PHEDMDMH_01332 1.91e-297 - - - - - - - -
PHEDMDMH_01333 9.2e-243 cps4G - - M - - - Glycosyltransferase Family 4
PHEDMDMH_01334 8.84e-137 cps4F - - M - - - Glycosyl transferases group 1
PHEDMDMH_01335 7.3e-86 cps4F - - M - - - Glycosyl transferases group 1
PHEDMDMH_01336 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
PHEDMDMH_01337 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
PHEDMDMH_01338 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
PHEDMDMH_01339 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
PHEDMDMH_01340 2.94e-160 epsB - - M - - - biosynthesis protein
PHEDMDMH_01341 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHEDMDMH_01342 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_01343 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
PHEDMDMH_01344 5.12e-31 - - - - - - - -
PHEDMDMH_01345 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
PHEDMDMH_01346 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
PHEDMDMH_01347 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PHEDMDMH_01348 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHEDMDMH_01349 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHEDMDMH_01350 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHEDMDMH_01351 1.39e-202 - - - S - - - Tetratricopeptide repeat
PHEDMDMH_01352 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHEDMDMH_01353 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHEDMDMH_01354 4.48e-261 - - - EGP - - - Major Facilitator Superfamily
PHEDMDMH_01355 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHEDMDMH_01356 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PHEDMDMH_01357 2.42e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PHEDMDMH_01358 4.44e-84 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PHEDMDMH_01359 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PHEDMDMH_01360 1.01e-115 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PHEDMDMH_01361 2.19e-163 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
PHEDMDMH_01362 3.01e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PHEDMDMH_01363 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHEDMDMH_01364 7.08e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
PHEDMDMH_01365 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
PHEDMDMH_01366 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PHEDMDMH_01367 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PHEDMDMH_01368 0.0 - - - - - - - -
PHEDMDMH_01369 0.0 icaA - - M - - - Glycosyl transferase family group 2
PHEDMDMH_01370 9.51e-135 - - - - - - - -
PHEDMDMH_01371 7.94e-195 - - - - - - - -
PHEDMDMH_01372 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PHEDMDMH_01373 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
PHEDMDMH_01374 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
PHEDMDMH_01375 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
PHEDMDMH_01376 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
PHEDMDMH_01377 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PHEDMDMH_01378 8.65e-228 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
PHEDMDMH_01379 4.94e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
PHEDMDMH_01380 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHEDMDMH_01381 6.45e-111 - - - - - - - -
PHEDMDMH_01382 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
PHEDMDMH_01383 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHEDMDMH_01384 3.45e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PHEDMDMH_01385 2.16e-39 - - - - - - - -
PHEDMDMH_01386 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
PHEDMDMH_01387 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHEDMDMH_01388 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHEDMDMH_01389 1.02e-155 - - - S - - - repeat protein
PHEDMDMH_01390 1.39e-156 pgm6 - - G - - - phosphoglycerate mutase
PHEDMDMH_01391 0.0 - - - N - - - domain, Protein
PHEDMDMH_01392 4.97e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
PHEDMDMH_01393 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
PHEDMDMH_01394 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
PHEDMDMH_01395 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
PHEDMDMH_01396 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHEDMDMH_01397 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
PHEDMDMH_01398 4.88e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
PHEDMDMH_01399 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHEDMDMH_01400 7.74e-47 - - - - - - - -
PHEDMDMH_01401 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PHEDMDMH_01402 1.41e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PHEDMDMH_01403 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHEDMDMH_01404 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
PHEDMDMH_01405 2.06e-187 ylmH - - S - - - S4 domain protein
PHEDMDMH_01406 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
PHEDMDMH_01407 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHEDMDMH_01408 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHEDMDMH_01409 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHEDMDMH_01410 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHEDMDMH_01411 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHEDMDMH_01412 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHEDMDMH_01413 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHEDMDMH_01414 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PHEDMDMH_01415 7.01e-76 ftsL - - D - - - Cell division protein FtsL
PHEDMDMH_01416 1.74e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHEDMDMH_01417 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PHEDMDMH_01418 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
PHEDMDMH_01419 4.1e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
PHEDMDMH_01420 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PHEDMDMH_01421 1.41e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHEDMDMH_01422 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
PHEDMDMH_01423 3.59e-301 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PHEDMDMH_01425 1.3e-206 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
PHEDMDMH_01426 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHEDMDMH_01427 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
PHEDMDMH_01428 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
PHEDMDMH_01429 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
PHEDMDMH_01430 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
PHEDMDMH_01431 6.31e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PHEDMDMH_01432 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHEDMDMH_01433 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
PHEDMDMH_01434 2.24e-148 yjbH - - Q - - - Thioredoxin
PHEDMDMH_01435 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PHEDMDMH_01436 1.85e-263 coiA - - S ko:K06198 - ko00000 Competence protein
PHEDMDMH_01437 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHEDMDMH_01438 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHEDMDMH_01439 3.83e-176 yhfI - - S - - - Metallo-beta-lactamase superfamily
PHEDMDMH_01440 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
PHEDMDMH_01441 2.17e-232 - - - L - - - Transposase IS66 family
PHEDMDMH_01443 4.9e-76 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
PHEDMDMH_01444 1.77e-35 - - - - - - - -
PHEDMDMH_01462 1.23e-53 - - - S - - - Enterocin A Immunity
PHEDMDMH_01463 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PHEDMDMH_01464 1.78e-139 - - - - - - - -
PHEDMDMH_01465 3.43e-303 - - - S - - - module of peptide synthetase
PHEDMDMH_01466 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
PHEDMDMH_01468 5.08e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
PHEDMDMH_01469 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHEDMDMH_01470 7.54e-200 - - - GM - - - NmrA-like family
PHEDMDMH_01471 4.08e-101 - - - K - - - MerR family regulatory protein
PHEDMDMH_01472 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHEDMDMH_01473 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
PHEDMDMH_01474 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHEDMDMH_01475 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
PHEDMDMH_01476 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
PHEDMDMH_01477 2.24e-116 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
PHEDMDMH_01478 3.54e-190 - - - S - - - haloacid dehalogenase-like hydrolase
PHEDMDMH_01479 2.69e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
PHEDMDMH_01480 6.26e-101 - - - - - - - -
PHEDMDMH_01481 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHEDMDMH_01482 2.93e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_01483 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
PHEDMDMH_01484 3.73e-263 - - - S - - - DUF218 domain
PHEDMDMH_01485 6.12e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
PHEDMDMH_01486 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHEDMDMH_01487 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHEDMDMH_01488 1.13e-200 - - - S - - - Putative adhesin
PHEDMDMH_01489 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
PHEDMDMH_01490 2.86e-68 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
PHEDMDMH_01491 1.07e-127 - - - KT - - - response to antibiotic
PHEDMDMH_01492 7.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PHEDMDMH_01493 3.52e-175 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_01494 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_01495 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PHEDMDMH_01496 2.07e-302 - - - EK - - - Aminotransferase, class I
PHEDMDMH_01497 3.36e-216 - - - K - - - LysR substrate binding domain
PHEDMDMH_01498 1.49e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_01499 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PHEDMDMH_01500 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
PHEDMDMH_01501 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
PHEDMDMH_01502 8.63e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PHEDMDMH_01503 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
PHEDMDMH_01504 7.16e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PHEDMDMH_01505 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
PHEDMDMH_01506 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHEDMDMH_01507 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
PHEDMDMH_01508 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHEDMDMH_01509 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHEDMDMH_01510 1.39e-160 - - - S - - - Protein of unknown function (DUF1275)
PHEDMDMH_01511 1.14e-159 vanR - - K - - - response regulator
PHEDMDMH_01512 5.61e-273 hpk31 - - T - - - Histidine kinase
PHEDMDMH_01513 3.61e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PHEDMDMH_01514 6.77e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
PHEDMDMH_01515 4.83e-166 - - - E - - - branched-chain amino acid
PHEDMDMH_01516 5.93e-73 - - - S - - - branched-chain amino acid
PHEDMDMH_01517 3.37e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
PHEDMDMH_01518 5.94e-40 - - - - - - - -
PHEDMDMH_01519 1.3e-91 - - - - - - - -
PHEDMDMH_01520 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PHEDMDMH_01521 2.83e-114 - - - - - - - -
PHEDMDMH_01522 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHEDMDMH_01523 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHEDMDMH_01524 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PHEDMDMH_01525 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PHEDMDMH_01526 1.26e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
PHEDMDMH_01527 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHEDMDMH_01528 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
PHEDMDMH_01529 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHEDMDMH_01530 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHEDMDMH_01531 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
PHEDMDMH_01532 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHEDMDMH_01533 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
PHEDMDMH_01534 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PHEDMDMH_01535 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHEDMDMH_01536 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PHEDMDMH_01537 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
PHEDMDMH_01538 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PHEDMDMH_01539 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHEDMDMH_01540 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PHEDMDMH_01541 7.94e-114 ykuL - - S - - - (CBS) domain
PHEDMDMH_01542 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHEDMDMH_01543 6.72e-289 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHEDMDMH_01544 1.9e-201 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
PHEDMDMH_01545 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHEDMDMH_01546 1.6e-96 - - - - - - - -
PHEDMDMH_01547 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_01548 1.81e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
PHEDMDMH_01549 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PHEDMDMH_01550 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
PHEDMDMH_01551 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
PHEDMDMH_01552 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
PHEDMDMH_01553 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHEDMDMH_01554 2.57e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
PHEDMDMH_01555 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
PHEDMDMH_01556 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
PHEDMDMH_01557 4.29e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
PHEDMDMH_01558 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
PHEDMDMH_01559 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
PHEDMDMH_01561 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
PHEDMDMH_01562 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHEDMDMH_01563 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
PHEDMDMH_01564 1.66e-150 - - - S - - - Calcineurin-like phosphoesterase
PHEDMDMH_01565 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PHEDMDMH_01566 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
PHEDMDMH_01567 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHEDMDMH_01568 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
PHEDMDMH_01569 8.38e-152 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
PHEDMDMH_01570 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHEDMDMH_01571 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
PHEDMDMH_01572 1.11e-84 - - - - - - - -
PHEDMDMH_01573 4.83e-151 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
PHEDMDMH_01574 2.59e-69 - - - - - - - -
PHEDMDMH_01575 2.54e-46 - - - S - - - Protein of unknown function (DUF2922)
PHEDMDMH_01576 1.17e-42 - - - - - - - -
PHEDMDMH_01577 5.7e-36 - - - - - - - -
PHEDMDMH_01578 3.82e-128 - - - K - - - DNA-templated transcription, initiation
PHEDMDMH_01579 1.39e-169 - - - - - - - -
PHEDMDMH_01580 3.93e-180 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
PHEDMDMH_01581 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PHEDMDMH_01582 5.34e-168 lytE - - M - - - NlpC/P60 family
PHEDMDMH_01583 8.01e-64 - - - K - - - sequence-specific DNA binding
PHEDMDMH_01584 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
PHEDMDMH_01585 4.22e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
PHEDMDMH_01586 1.13e-257 yueF - - S - - - AI-2E family transporter
PHEDMDMH_01587 3.5e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
PHEDMDMH_01588 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
PHEDMDMH_01589 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PHEDMDMH_01590 4.77e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
PHEDMDMH_01591 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
PHEDMDMH_01592 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHEDMDMH_01593 0.0 - - - - - - - -
PHEDMDMH_01594 2.12e-252 - - - M - - - MucBP domain
PHEDMDMH_01595 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
PHEDMDMH_01596 4.78e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
PHEDMDMH_01597 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
PHEDMDMH_01598 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_01599 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHEDMDMH_01600 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHEDMDMH_01601 2.81e-257 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHEDMDMH_01602 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHEDMDMH_01603 3.4e-85 - - - K - - - Winged helix DNA-binding domain
PHEDMDMH_01604 2.5e-132 - - - L - - - Integrase
PHEDMDMH_01605 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
PHEDMDMH_01606 5.6e-41 - - - - - - - -
PHEDMDMH_01607 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
PHEDMDMH_01608 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHEDMDMH_01609 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
PHEDMDMH_01610 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
PHEDMDMH_01611 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHEDMDMH_01612 8.93e-290 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PHEDMDMH_01613 5.8e-291 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHEDMDMH_01614 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
PHEDMDMH_01615 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHEDMDMH_01616 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
PHEDMDMH_01617 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
PHEDMDMH_01618 1.67e-53 - - - - - - - -
PHEDMDMH_01619 8.01e-97 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
PHEDMDMH_01620 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PHEDMDMH_01621 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
PHEDMDMH_01622 1.47e-144 - - - S - - - VIT family
PHEDMDMH_01623 2.66e-155 - - - S - - - membrane
PHEDMDMH_01624 9.43e-203 - - - EG - - - EamA-like transporter family
PHEDMDMH_01625 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
PHEDMDMH_01626 3.57e-150 - - - GM - - - NmrA-like family
PHEDMDMH_01627 4.79e-21 - - - - - - - -
PHEDMDMH_01628 3.78e-73 - - - - - - - -
PHEDMDMH_01629 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PHEDMDMH_01630 1.36e-112 - - - - - - - -
PHEDMDMH_01631 1.22e-81 - - - - - - - -
PHEDMDMH_01632 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
PHEDMDMH_01633 1.7e-70 - - - - - - - -
PHEDMDMH_01634 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
PHEDMDMH_01635 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
PHEDMDMH_01636 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
PHEDMDMH_01637 6.47e-208 - - - GM - - - NmrA-like family
PHEDMDMH_01638 4.75e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
PHEDMDMH_01639 4.28e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_01640 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
PHEDMDMH_01641 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
PHEDMDMH_01642 3.58e-36 - - - S - - - Belongs to the LOG family
PHEDMDMH_01643 7.12e-256 glmS2 - - M - - - SIS domain
PHEDMDMH_01644 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PHEDMDMH_01645 3.05e-281 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
PHEDMDMH_01646 2.32e-160 - - - S - - - YjbR
PHEDMDMH_01648 0.0 cadA - - P - - - P-type ATPase
PHEDMDMH_01649 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
PHEDMDMH_01650 8.79e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
PHEDMDMH_01651 4.29e-101 - - - - - - - -
PHEDMDMH_01652 9.9e-49 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
PHEDMDMH_01653 2.42e-127 - - - FG - - - HIT domain
PHEDMDMH_01654 6.07e-223 ydhF - - S - - - Aldo keto reductase
PHEDMDMH_01655 8.93e-71 - - - S - - - Pfam:DUF59
PHEDMDMH_01656 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHEDMDMH_01657 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
PHEDMDMH_01658 1.26e-247 - - - V - - - Beta-lactamase
PHEDMDMH_01659 3.74e-125 - - - V - - - VanZ like family
PHEDMDMH_01660 3.6e-211 - - - I - - - Diacylglycerol kinase catalytic domain
PHEDMDMH_01661 5.58e-87 - - - S - - - Protein of unknown function (DUF805)
PHEDMDMH_01662 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
PHEDMDMH_01663 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
PHEDMDMH_01664 2.05e-55 - - - - - - - -
PHEDMDMH_01665 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
PHEDMDMH_01666 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
PHEDMDMH_01667 1.05e-41 - - - L ko:K07497 - ko00000 hmm pf00665
PHEDMDMH_01668 1.33e-273 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
PHEDMDMH_01669 8.23e-39 - - - - - - - -
PHEDMDMH_01670 1.48e-71 - - - - - - - -
PHEDMDMH_01671 1.14e-193 - - - O - - - Band 7 protein
PHEDMDMH_01672 0.0 - - - EGP - - - Major Facilitator
PHEDMDMH_01673 6.05e-121 - - - K - - - transcriptional regulator
PHEDMDMH_01674 3.53e-124 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHEDMDMH_01675 2.01e-113 ykhA - - I - - - Thioesterase superfamily
PHEDMDMH_01676 2.16e-206 - - - K - - - LysR substrate binding domain
PHEDMDMH_01677 1.48e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PHEDMDMH_01678 5.01e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
PHEDMDMH_01679 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PHEDMDMH_01680 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
PHEDMDMH_01681 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHEDMDMH_01682 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
PHEDMDMH_01683 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PHEDMDMH_01684 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHEDMDMH_01685 7.64e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHEDMDMH_01686 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PHEDMDMH_01687 3.47e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
PHEDMDMH_01688 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHEDMDMH_01689 1.62e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHEDMDMH_01690 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHEDMDMH_01691 1.62e-229 yneE - - K - - - Transcriptional regulator
PHEDMDMH_01692 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PHEDMDMH_01694 1.49e-77 - - - S - - - Protein of unknown function (DUF1648)
PHEDMDMH_01695 2.69e-252 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PHEDMDMH_01696 7.96e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
PHEDMDMH_01697 1.62e-276 - - - E - - - glutamate:sodium symporter activity
PHEDMDMH_01698 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
PHEDMDMH_01699 2.04e-226 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
PHEDMDMH_01700 5.89e-126 entB - - Q - - - Isochorismatase family
PHEDMDMH_01701 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PHEDMDMH_01702 6.25e-288 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PHEDMDMH_01703 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
PHEDMDMH_01704 1.2e-165 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PHEDMDMH_01705 2.01e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PHEDMDMH_01706 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
PHEDMDMH_01707 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
PHEDMDMH_01709 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
PHEDMDMH_01710 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PHEDMDMH_01711 9.06e-112 - - - - - - - -
PHEDMDMH_01712 7.92e-199 - - - M - - - LPXTG-motif cell wall anchor domain protein
PHEDMDMH_01713 0.0 - - - S - - - membrane
PHEDMDMH_01714 4.29e-26 - - - S - - - NUDIX domain
PHEDMDMH_01715 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHEDMDMH_01716 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
PHEDMDMH_01717 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
PHEDMDMH_01718 4.43e-129 - - - - - - - -
PHEDMDMH_01719 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHEDMDMH_01720 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
PHEDMDMH_01721 6.59e-227 - - - K - - - LysR substrate binding domain
PHEDMDMH_01722 2.41e-233 - - - M - - - Peptidase family S41
PHEDMDMH_01723 1.05e-272 - - - - - - - -
PHEDMDMH_01724 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHEDMDMH_01725 0.0 yhaN - - L - - - AAA domain
PHEDMDMH_01726 3.67e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
PHEDMDMH_01727 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
PHEDMDMH_01728 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PHEDMDMH_01729 2.43e-18 - - - - - - - -
PHEDMDMH_01730 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PHEDMDMH_01731 5.58e-271 arcT - - E - - - Aminotransferase
PHEDMDMH_01732 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
PHEDMDMH_01733 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
PHEDMDMH_01734 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHEDMDMH_01735 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
PHEDMDMH_01736 1.67e-217 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
PHEDMDMH_01737 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_01738 1.02e-285 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_01739 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHEDMDMH_01740 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
PHEDMDMH_01741 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
PHEDMDMH_01742 0.0 celR - - K - - - PRD domain
PHEDMDMH_01743 6.25e-138 - - - - - - - -
PHEDMDMH_01744 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
PHEDMDMH_01745 4.64e-106 - - - - - - - -
PHEDMDMH_01746 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PHEDMDMH_01747 8.2e-102 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
PHEDMDMH_01750 1.79e-42 - - - - - - - -
PHEDMDMH_01751 2.69e-316 dinF - - V - - - MatE
PHEDMDMH_01752 7.77e-234 - - - D ko:K06889 - ko00000 Alpha beta
PHEDMDMH_01753 1.01e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PHEDMDMH_01754 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
PHEDMDMH_01755 2.05e-72 - - - S - - - Enterocin A Immunity
PHEDMDMH_01756 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHEDMDMH_01757 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHEDMDMH_01758 4.17e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHEDMDMH_01759 6.97e-134 amiF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
PHEDMDMH_01760 4.29e-33 amiF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
PHEDMDMH_01761 1.84e-241 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PHEDMDMH_01762 2.53e-200 - - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHEDMDMH_01763 0.0 amiC - - U ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_01764 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
PHEDMDMH_01765 5.9e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
PHEDMDMH_01766 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHEDMDMH_01768 2.2e-105 - - - - - - - -
PHEDMDMH_01769 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
PHEDMDMH_01771 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
PHEDMDMH_01772 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHEDMDMH_01773 1.54e-228 ydbI - - K - - - AI-2E family transporter
PHEDMDMH_01774 1.68e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
PHEDMDMH_01775 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PHEDMDMH_01776 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PHEDMDMH_01777 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
PHEDMDMH_01778 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_01779 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
PHEDMDMH_01780 6.62e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
PHEDMDMH_01782 8.03e-28 - - - - - - - -
PHEDMDMH_01783 1.31e-122 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
PHEDMDMH_01784 1.37e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
PHEDMDMH_01785 3.59e-130 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
PHEDMDMH_01786 5.04e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PHEDMDMH_01787 1.04e-133 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
PHEDMDMH_01788 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PHEDMDMH_01789 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PHEDMDMH_01790 4.08e-107 cvpA - - S - - - Colicin V production protein
PHEDMDMH_01791 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PHEDMDMH_01792 8.83e-317 - - - EGP - - - Major Facilitator
PHEDMDMH_01794 4.54e-54 - - - - - - - -
PHEDMDMH_01795 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
PHEDMDMH_01796 2.81e-90 - - - S - - - Domain of unknown function (DUF3284)
PHEDMDMH_01797 8.86e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_01798 1.13e-228 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
PHEDMDMH_01799 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PHEDMDMH_01800 5.02e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
PHEDMDMH_01801 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PHEDMDMH_01802 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
PHEDMDMH_01803 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
PHEDMDMH_01804 6.22e-140 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
PHEDMDMH_01805 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PHEDMDMH_01806 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PHEDMDMH_01807 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PHEDMDMH_01808 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PHEDMDMH_01809 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PHEDMDMH_01810 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
PHEDMDMH_01811 1.64e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
PHEDMDMH_01812 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
PHEDMDMH_01813 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
PHEDMDMH_01814 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
PHEDMDMH_01815 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PHEDMDMH_01816 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
PHEDMDMH_01817 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
PHEDMDMH_01818 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHEDMDMH_01819 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHEDMDMH_01820 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PHEDMDMH_01821 1.12e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHEDMDMH_01822 3.8e-223 - - - K - - - Transcriptional regulator, LysR family
PHEDMDMH_01823 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
PHEDMDMH_01824 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHEDMDMH_01825 2.33e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHEDMDMH_01826 1.64e-72 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
PHEDMDMH_01827 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
PHEDMDMH_01828 2.57e-212 yjdB - - S - - - Domain of unknown function (DUF4767)
PHEDMDMH_01829 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
PHEDMDMH_01830 3.25e-181 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PHEDMDMH_01831 3.07e-84 - - - S - - - Putative inner membrane protein (DUF1819)
PHEDMDMH_01832 1.15e-93 - - - S - - - Domain of unknown function (DUF1788)
PHEDMDMH_01833 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PHEDMDMH_01834 0.0 - - - LV - - - Eco57I restriction-modification methylase
PHEDMDMH_01835 2.15e-189 - - - L - - - Belongs to the 'phage' integrase family
PHEDMDMH_01836 3.73e-221 - - - LV - - - Eco57I restriction-modification methylase
PHEDMDMH_01837 2.34e-280 - - - S - - - PglZ domain
PHEDMDMH_01838 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
PHEDMDMH_01839 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
PHEDMDMH_01840 6.09e-53 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
PHEDMDMH_01841 5.7e-199 is18 - - L - - - Integrase core domain
PHEDMDMH_01842 1.23e-108 - - - L - - - PFAM Integrase catalytic region
PHEDMDMH_01844 1.39e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
PHEDMDMH_01845 0.0 - - - M - - - MucBP domain
PHEDMDMH_01846 1.42e-08 - - - - - - - -
PHEDMDMH_01847 1.27e-115 - - - S - - - AAA domain
PHEDMDMH_01848 1.97e-175 - - - K - - - sequence-specific DNA binding
PHEDMDMH_01849 1.05e-121 - - - K - - - Helix-turn-helix domain
PHEDMDMH_01850 6.52e-219 - - - K - - - Transcriptional regulator
PHEDMDMH_01851 0.0 - - - C - - - FMN_bind
PHEDMDMH_01853 1.23e-85 tnpR1 - - L - - - Resolvase, N terminal domain
PHEDMDMH_01854 0.0 - - - EGP - - - Major Facilitator
PHEDMDMH_01855 2.56e-135 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_01856 3.89e-56 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PHEDMDMH_01857 5.4e-11 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PHEDMDMH_01858 1.15e-192 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_01859 1.46e-46 - - - - - - - -
PHEDMDMH_01860 6.94e-229 repA - - S - - - Replication initiator protein A
PHEDMDMH_01861 3.67e-37 - - - - - - - -
PHEDMDMH_01862 7.42e-37 - - - S - - - protein conserved in bacteria
PHEDMDMH_01863 1.12e-50 - - - - - - - -
PHEDMDMH_01864 3e-32 - - - - - - - -
PHEDMDMH_01865 0.0 traA - - L - - - MobA MobL family protein
PHEDMDMH_01866 1.86e-45 - - - - - - - -
PHEDMDMH_01867 9.68e-128 - - - - - - - -
PHEDMDMH_01868 1.81e-67 - - - S - - - Cag pathogenicity island, type IV secretory system
PHEDMDMH_01869 8.94e-70 - - - - - - - -
PHEDMDMH_01870 8.68e-150 - - - - - - - -
PHEDMDMH_01871 0.0 - - - U - - - AAA-like domain
PHEDMDMH_01872 8.81e-317 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
PHEDMDMH_01873 4.29e-276 - - - M - - - CHAP domain
PHEDMDMH_01874 1.58e-120 - - - - - - - -
PHEDMDMH_01875 8.31e-76 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
PHEDMDMH_01876 5.23e-102 - - - - - - - -
PHEDMDMH_01877 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
PHEDMDMH_01878 2.43e-78 - - - - - - - -
PHEDMDMH_01879 3.42e-198 - - - - - - - -
PHEDMDMH_01880 3.72e-81 - - - - - - - -
PHEDMDMH_01881 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHEDMDMH_01882 8.86e-38 - - - - - - - -
PHEDMDMH_01883 4.1e-237 - - - L - - - Psort location Cytoplasmic, score
PHEDMDMH_01884 6.18e-185 - - - L - - - DNA restriction-modification system
PHEDMDMH_01885 3.27e-70 - - - V - - - Restriction endonuclease
PHEDMDMH_01886 5.11e-29 - - - L - - - Transposase DDE domain
PHEDMDMH_01889 1.05e-275 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
PHEDMDMH_01890 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PHEDMDMH_01891 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PHEDMDMH_01892 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PHEDMDMH_01893 1.83e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PHEDMDMH_01894 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
PHEDMDMH_01895 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHEDMDMH_01896 2.69e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHEDMDMH_01897 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
PHEDMDMH_01898 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
PHEDMDMH_01899 6.77e-70 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
PHEDMDMH_01900 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHEDMDMH_01901 3.62e-212 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHEDMDMH_01902 1.98e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PHEDMDMH_01903 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PHEDMDMH_01904 3.69e-159 - - - T - - - Putative diguanylate phosphodiesterase
PHEDMDMH_01905 0.0 nox - - C - - - NADH oxidase
PHEDMDMH_01906 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHEDMDMH_01907 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
PHEDMDMH_01908 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
PHEDMDMH_01909 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PHEDMDMH_01910 2.4e-169 - - - T - - - Putative diguanylate phosphodiesterase
PHEDMDMH_01911 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHEDMDMH_01912 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PHEDMDMH_01913 4.38e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
PHEDMDMH_01914 9.07e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
PHEDMDMH_01915 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHEDMDMH_01916 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHEDMDMH_01917 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHEDMDMH_01918 3.06e-301 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PHEDMDMH_01919 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PHEDMDMH_01920 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
PHEDMDMH_01921 2e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PHEDMDMH_01922 1.46e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PHEDMDMH_01923 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PHEDMDMH_01924 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
PHEDMDMH_01925 2.11e-223 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHEDMDMH_01926 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHEDMDMH_01928 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
PHEDMDMH_01929 9.53e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
PHEDMDMH_01930 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHEDMDMH_01931 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PHEDMDMH_01932 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHEDMDMH_01933 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHEDMDMH_01934 2.42e-169 - - - - - - - -
PHEDMDMH_01935 6.4e-201 eriC - - P ko:K03281 - ko00000 chloride
PHEDMDMH_01936 2.05e-144 eriC - - P ko:K03281 - ko00000 chloride
PHEDMDMH_01937 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
PHEDMDMH_01938 1.05e-176 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
PHEDMDMH_01939 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHEDMDMH_01940 9.78e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHEDMDMH_01941 0.0 - - - M - - - Domain of unknown function (DUF5011)
PHEDMDMH_01942 0.0 - - - M - - - Domain of unknown function (DUF5011)
PHEDMDMH_01943 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_01944 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_01945 7.98e-137 - - - - - - - -
PHEDMDMH_01946 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHEDMDMH_01947 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHEDMDMH_01948 5e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
PHEDMDMH_01949 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
PHEDMDMH_01950 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
PHEDMDMH_01951 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PHEDMDMH_01952 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PHEDMDMH_01953 2.43e-210 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
PHEDMDMH_01954 2.54e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
PHEDMDMH_01955 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
PHEDMDMH_01956 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PHEDMDMH_01957 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
PHEDMDMH_01958 3.39e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHEDMDMH_01959 2.54e-181 ybbR - - S - - - YbbR-like protein
PHEDMDMH_01960 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHEDMDMH_01961 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHEDMDMH_01962 4.47e-158 - - - T - - - EAL domain
PHEDMDMH_01963 3.27e-189 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
PHEDMDMH_01964 4.12e-06 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_01965 4.87e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
PHEDMDMH_01966 3.38e-70 - - - - - - - -
PHEDMDMH_01967 2.49e-95 - - - - - - - -
PHEDMDMH_01968 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
PHEDMDMH_01969 5.79e-196 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
PHEDMDMH_01970 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHEDMDMH_01971 6.37e-186 - - - - - - - -
PHEDMDMH_01973 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
PHEDMDMH_01974 3.88e-46 - - - - - - - -
PHEDMDMH_01975 2.08e-117 - - - V - - - VanZ like family
PHEDMDMH_01976 1.02e-312 - - - EGP - - - Major Facilitator
PHEDMDMH_01977 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
PHEDMDMH_01978 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PHEDMDMH_01979 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
PHEDMDMH_01980 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
PHEDMDMH_01981 6.16e-107 - - - K - - - Transcriptional regulator
PHEDMDMH_01982 1.36e-27 - - - - - - - -
PHEDMDMH_01983 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PHEDMDMH_01984 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PHEDMDMH_01985 1.06e-195 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PHEDMDMH_01986 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PHEDMDMH_01987 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
PHEDMDMH_01988 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHEDMDMH_01989 0.0 oatA - - I - - - Acyltransferase
PHEDMDMH_01990 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHEDMDMH_01991 1.89e-90 - - - O - - - OsmC-like protein
PHEDMDMH_01992 1.09e-60 - - - - - - - -
PHEDMDMH_01993 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
PHEDMDMH_01994 6.12e-115 - - - - - - - -
PHEDMDMH_01995 1.23e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
PHEDMDMH_01996 7.48e-96 - - - F - - - Nudix hydrolase
PHEDMDMH_01997 1.48e-27 - - - - - - - -
PHEDMDMH_01998 2.45e-134 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
PHEDMDMH_01999 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PHEDMDMH_02000 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
PHEDMDMH_02001 1.01e-188 - - - - - - - -
PHEDMDMH_02002 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
PHEDMDMH_02003 7.9e-269 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PHEDMDMH_02004 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHEDMDMH_02005 5.2e-54 - - - - - - - -
PHEDMDMH_02007 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02008 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PHEDMDMH_02009 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_02010 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_02011 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHEDMDMH_02012 7.77e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
PHEDMDMH_02013 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
PHEDMDMH_02014 3.16e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
PHEDMDMH_02015 0.0 steT - - E ko:K03294 - ko00000 amino acid
PHEDMDMH_02016 1.26e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PHEDMDMH_02017 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
PHEDMDMH_02018 8.83e-93 - - - K - - - MarR family
PHEDMDMH_02019 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
PHEDMDMH_02020 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
PHEDMDMH_02021 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_02022 1.7e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHEDMDMH_02023 4.6e-102 rppH3 - - F - - - NUDIX domain
PHEDMDMH_02024 1.95e-61 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
PHEDMDMH_02025 1.61e-36 - - - - - - - -
PHEDMDMH_02026 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
PHEDMDMH_02027 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
PHEDMDMH_02028 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
PHEDMDMH_02029 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PHEDMDMH_02030 1.11e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
PHEDMDMH_02031 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PHEDMDMH_02032 2.08e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
PHEDMDMH_02033 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PHEDMDMH_02034 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PHEDMDMH_02036 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
PHEDMDMH_02037 3.61e-76 yeeA - - V - - - Type II restriction enzyme, methylase subunits
PHEDMDMH_02038 0.0 - - - L - - - DEAD-like helicases superfamily
PHEDMDMH_02039 3.66e-162 yeeC - - P - - - T5orf172
PHEDMDMH_02042 1.96e-81 - - - L - - - AAA domain
PHEDMDMH_02043 6.18e-130 - - - K - - - Transcriptional regulator, AbiEi antitoxin
PHEDMDMH_02044 9.75e-176 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
PHEDMDMH_02045 3.01e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
PHEDMDMH_02046 1.04e-69 - - - - - - - -
PHEDMDMH_02047 8.89e-80 - - - K - - - Helix-turn-helix domain
PHEDMDMH_02048 1.57e-140 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_02049 1.22e-242 - - - S - - - Cysteine-rich secretory protein family
PHEDMDMH_02050 1.59e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
PHEDMDMH_02051 1.96e-117 - - - D - - - nuclear chromosome segregation
PHEDMDMH_02052 6.46e-111 - - - - - - - -
PHEDMDMH_02054 6.19e-208 - - - K - - - Transcriptional regulator
PHEDMDMH_02055 1.2e-206 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
PHEDMDMH_02056 1.66e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
PHEDMDMH_02057 2.45e-101 - - - K - - - Winged helix DNA-binding domain
PHEDMDMH_02058 0.0 ycaM - - E - - - amino acid
PHEDMDMH_02059 2.1e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
PHEDMDMH_02060 4.3e-44 - - - - - - - -
PHEDMDMH_02061 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PHEDMDMH_02062 7.65e-81 - - - M - - - Domain of unknown function (DUF5011)
PHEDMDMH_02063 0.0 - - - M - - - Domain of unknown function (DUF5011)
PHEDMDMH_02064 1.66e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
PHEDMDMH_02065 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
PHEDMDMH_02066 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
PHEDMDMH_02067 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PHEDMDMH_02068 2.25e-73 - - - EG - - - EamA-like transporter family
PHEDMDMH_02069 1.2e-107 - - - EG - - - EamA-like transporter family
PHEDMDMH_02070 2.05e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHEDMDMH_02071 5.06e-196 - - - S - - - hydrolase
PHEDMDMH_02072 7.63e-107 - - - - - - - -
PHEDMDMH_02073 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
PHEDMDMH_02074 1.4e-181 epsV - - S - - - glycosyl transferase family 2
PHEDMDMH_02075 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
PHEDMDMH_02076 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHEDMDMH_02077 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
PHEDMDMH_02078 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_02079 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_02080 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
PHEDMDMH_02081 2.61e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PHEDMDMH_02082 3.61e-244 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PHEDMDMH_02083 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PHEDMDMH_02084 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PHEDMDMH_02085 4.28e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
PHEDMDMH_02086 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PHEDMDMH_02087 1.3e-110 queT - - S - - - QueT transporter
PHEDMDMH_02088 5.29e-211 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
PHEDMDMH_02089 8.1e-157 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
PHEDMDMH_02090 4.87e-148 - - - S - - - (CBS) domain
PHEDMDMH_02091 0.0 - - - S - - - Putative peptidoglycan binding domain
PHEDMDMH_02092 1.61e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PHEDMDMH_02093 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHEDMDMH_02094 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHEDMDMH_02095 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
PHEDMDMH_02096 7.72e-57 yabO - - J - - - S4 domain protein
PHEDMDMH_02098 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PHEDMDMH_02099 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
PHEDMDMH_02100 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHEDMDMH_02101 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
PHEDMDMH_02102 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHEDMDMH_02103 1.11e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHEDMDMH_02104 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHEDMDMH_02105 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PHEDMDMH_02106 9.59e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_02107 1.32e-170 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_02108 5.68e-155 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_02109 8.31e-292 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
PHEDMDMH_02110 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
PHEDMDMH_02111 5.62e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
PHEDMDMH_02112 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
PHEDMDMH_02113 1.17e-135 - - - K - - - transcriptional regulator
PHEDMDMH_02114 1.41e-141 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
PHEDMDMH_02115 1.49e-63 - - - - - - - -
PHEDMDMH_02116 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
PHEDMDMH_02117 7.18e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PHEDMDMH_02118 2.87e-56 - - - - - - - -
PHEDMDMH_02119 3.35e-75 - - - - - - - -
PHEDMDMH_02120 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_02121 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
PHEDMDMH_02122 2.42e-65 - - - - - - - -
PHEDMDMH_02123 1.9e-165 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
PHEDMDMH_02124 0.0 hpk2 - - T - - - Histidine kinase
PHEDMDMH_02125 2.39e-31 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_02126 0.0 ydiC - - EGP - - - Major Facilitator
PHEDMDMH_02127 1.55e-55 - - - - - - - -
PHEDMDMH_02128 4.48e-52 - - - - - - - -
PHEDMDMH_02129 1.15e-152 - - - - - - - -
PHEDMDMH_02130 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PHEDMDMH_02131 8.62e-155 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_02132 8.9e-96 ywnA - - K - - - Transcriptional regulator
PHEDMDMH_02133 2.33e-56 - - - K - - - HxlR-like helix-turn-helix
PHEDMDMH_02134 1.31e-139 yoaZ - - S - - - intracellular protease amidase
PHEDMDMH_02135 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
PHEDMDMH_02136 2.23e-279 - - - S - - - Membrane
PHEDMDMH_02137 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
PHEDMDMH_02138 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_02139 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PHEDMDMH_02140 5.15e-16 - - - - - - - -
PHEDMDMH_02141 2.09e-85 - - - - - - - -
PHEDMDMH_02142 7.36e-316 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_02143 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_02144 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
PHEDMDMH_02145 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PHEDMDMH_02146 0.0 - - - S - - - MucBP domain
PHEDMDMH_02147 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
PHEDMDMH_02148 1.06e-205 - - - K - - - LysR substrate binding domain
PHEDMDMH_02149 1.07e-200 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
PHEDMDMH_02150 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
PHEDMDMH_02151 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHEDMDMH_02152 6.88e-152 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_02153 2e-62 - - - K - - - Helix-turn-helix domain
PHEDMDMH_02154 1.92e-115 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHEDMDMH_02155 2.5e-66 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PHEDMDMH_02156 7.85e-114 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02157 6.79e-53 - - - - - - - -
PHEDMDMH_02158 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHEDMDMH_02159 1.6e-233 ydbI - - K - - - AI-2E family transporter
PHEDMDMH_02160 9.28e-271 xylR - - GK - - - ROK family
PHEDMDMH_02161 2.92e-143 - - - - - - - -
PHEDMDMH_02162 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
PHEDMDMH_02163 3.32e-210 - - - - - - - -
PHEDMDMH_02164 1.86e-256 pkn2 - - KLT - - - Protein tyrosine kinase
PHEDMDMH_02165 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
PHEDMDMH_02166 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
PHEDMDMH_02167 5.61e-98 - - - S - - - Psort location Cytoplasmic, score
PHEDMDMH_02168 1.82e-158 epsB - - M - - - biosynthesis protein
PHEDMDMH_02169 9.65e-163 ywqD - - D - - - Capsular exopolysaccharide family
PHEDMDMH_02170 5.05e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
PHEDMDMH_02171 8.98e-225 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
PHEDMDMH_02172 4.65e-157 tuaA - - M - - - Bacterial sugar transferase
PHEDMDMH_02173 2.15e-26 lsgF - - M - - - Glycosyltransferases involved in cell wall biogenesis
PHEDMDMH_02174 7.62e-16 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase dehydratase family protein
PHEDMDMH_02175 6.39e-82 tuaA - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PHEDMDMH_02176 1.54e-82 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PHEDMDMH_02177 2.18e-246 - - - L - - - Transposase and inactivated derivatives, IS30 family
PHEDMDMH_02178 1.09e-35 - - - - - - - -
PHEDMDMH_02179 4.01e-31 - - - - - - - -
PHEDMDMH_02181 2.21e-134 traA - - L - - - MobA MobL family protein
PHEDMDMH_02182 0.0 traA - - L - - - MobA MobL family protein
PHEDMDMH_02183 8.56e-226 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
PHEDMDMH_02184 2.94e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
PHEDMDMH_02185 5.67e-257 cps3I - - G - - - Acyltransferase family
PHEDMDMH_02186 1.75e-256 cps3H - - - - - - -
PHEDMDMH_02187 2.03e-208 cps3F - - - - - - -
PHEDMDMH_02188 3.98e-143 cps3E - - - - - - -
PHEDMDMH_02189 5.58e-260 cps3D - - - - - - -
PHEDMDMH_02190 6.91e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
PHEDMDMH_02191 7.72e-228 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
PHEDMDMH_02192 4.93e-170 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
PHEDMDMH_02194 6.17e-71 - - - S - - - SMI1-KNR4 cell-wall
PHEDMDMH_02196 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
PHEDMDMH_02197 1.84e-261 - - - EGP - - - Transporter, major facilitator family protein
PHEDMDMH_02198 3.41e-187 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PHEDMDMH_02199 3.21e-210 - - - K - - - Transcriptional regulator
PHEDMDMH_02200 3.41e-191 - - - S - - - hydrolase
PHEDMDMH_02201 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PHEDMDMH_02202 1.78e-264 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHEDMDMH_02204 2.2e-149 - - - - - - - -
PHEDMDMH_02205 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
PHEDMDMH_02206 2.4e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
PHEDMDMH_02207 5.07e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PHEDMDMH_02208 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_02209 5.44e-174 - - - K - - - UTRA domain
PHEDMDMH_02210 2.63e-200 estA - - S - - - Putative esterase
PHEDMDMH_02211 4.93e-82 - - - - - - - -
PHEDMDMH_02212 1.06e-262 - - - EGP - - - Major Facilitator Superfamily
PHEDMDMH_02213 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
PHEDMDMH_02214 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
PHEDMDMH_02215 2.73e-274 ybfG - - M - - - peptidoglycan-binding domain-containing protein
PHEDMDMH_02219 1.12e-06 B4168_4126 - - L ko:K07493 - ko00000 Transposase
PHEDMDMH_02221 7.55e-61 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
PHEDMDMH_02223 2.32e-17 ygzD - - K ko:K07729 - ko00000,ko03000 transcriptional
PHEDMDMH_02225 8.21e-77 - - - - - - - -
PHEDMDMH_02226 1.7e-200 - - - L - - - Initiator Replication protein
PHEDMDMH_02227 1.24e-39 - - - - - - - -
PHEDMDMH_02228 1.04e-42 - - - L - - - Integrase
PHEDMDMH_02229 3.2e-70 - - - - - - - -
PHEDMDMH_02230 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHEDMDMH_02231 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PHEDMDMH_02232 6.42e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHEDMDMH_02233 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PHEDMDMH_02234 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PHEDMDMH_02235 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHEDMDMH_02236 2.95e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHEDMDMH_02237 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHEDMDMH_02238 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PHEDMDMH_02239 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHEDMDMH_02240 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHEDMDMH_02241 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHEDMDMH_02242 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHEDMDMH_02243 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
PHEDMDMH_02244 2.89e-75 yloU - - S - - - Asp23 family, cell envelope-related function
PHEDMDMH_02245 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PHEDMDMH_02246 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PHEDMDMH_02247 3.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PHEDMDMH_02248 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHEDMDMH_02249 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PHEDMDMH_02250 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PHEDMDMH_02251 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PHEDMDMH_02252 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHEDMDMH_02253 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHEDMDMH_02254 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHEDMDMH_02255 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHEDMDMH_02256 2.83e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PHEDMDMH_02257 8.28e-73 - - - - - - - -
PHEDMDMH_02258 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_02259 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHEDMDMH_02260 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_02261 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02262 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PHEDMDMH_02263 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PHEDMDMH_02264 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
PHEDMDMH_02265 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PHEDMDMH_02266 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHEDMDMH_02267 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHEDMDMH_02268 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHEDMDMH_02269 2.82e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHEDMDMH_02270 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
PHEDMDMH_02271 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHEDMDMH_02272 3.49e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
PHEDMDMH_02273 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PHEDMDMH_02274 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
PHEDMDMH_02275 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PHEDMDMH_02276 8.15e-125 - - - K - - - Transcriptional regulator
PHEDMDMH_02277 9.81e-27 - - - - - - - -
PHEDMDMH_02280 2.97e-41 - - - - - - - -
PHEDMDMH_02281 3.11e-73 - - - - - - - -
PHEDMDMH_02282 8.37e-126 - - - S - - - Protein conserved in bacteria
PHEDMDMH_02283 1.34e-232 - - - - - - - -
PHEDMDMH_02284 1.77e-205 - - - - - - - -
PHEDMDMH_02285 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PHEDMDMH_02286 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
PHEDMDMH_02287 3.8e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHEDMDMH_02288 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
PHEDMDMH_02289 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
PHEDMDMH_02290 1.15e-89 yqhL - - P - - - Rhodanese-like protein
PHEDMDMH_02291 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
PHEDMDMH_02292 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PHEDMDMH_02293 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
PHEDMDMH_02294 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
PHEDMDMH_02295 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHEDMDMH_02296 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PHEDMDMH_02297 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PHEDMDMH_02298 0.0 - - - S - - - membrane
PHEDMDMH_02299 2.5e-71 yneR - - S - - - Belongs to the HesB IscA family
PHEDMDMH_02300 2.33e-98 - - - K - - - LytTr DNA-binding domain
PHEDMDMH_02301 3.78e-143 - - - S - - - membrane
PHEDMDMH_02302 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHEDMDMH_02303 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PHEDMDMH_02304 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PHEDMDMH_02305 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHEDMDMH_02306 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHEDMDMH_02307 4.45e-83 yodB - - K - - - Transcriptional regulator, HxlR family
PHEDMDMH_02308 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHEDMDMH_02309 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHEDMDMH_02310 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PHEDMDMH_02311 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHEDMDMH_02312 1.77e-122 - - - S - - - SdpI/YhfL protein family
PHEDMDMH_02313 9.59e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PHEDMDMH_02314 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
PHEDMDMH_02315 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
PHEDMDMH_02316 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PHEDMDMH_02317 1.38e-155 csrR - - K - - - response regulator
PHEDMDMH_02318 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
PHEDMDMH_02319 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHEDMDMH_02320 1.09e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHEDMDMH_02321 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
PHEDMDMH_02322 1.49e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
PHEDMDMH_02323 3.04e-280 ylbM - - S - - - Belongs to the UPF0348 family
PHEDMDMH_02324 3.3e-180 yqeM - - Q - - - Methyltransferase
PHEDMDMH_02325 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHEDMDMH_02326 1.71e-149 yqeK - - H - - - Hydrolase, HD family
PHEDMDMH_02327 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHEDMDMH_02328 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
PHEDMDMH_02329 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
PHEDMDMH_02330 1.34e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
PHEDMDMH_02331 8.99e-114 - - - - - - - -
PHEDMDMH_02332 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
PHEDMDMH_02333 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PHEDMDMH_02334 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
PHEDMDMH_02335 1.18e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PHEDMDMH_02336 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
PHEDMDMH_02337 1.87e-72 - - - - - - - -
PHEDMDMH_02338 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHEDMDMH_02339 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PHEDMDMH_02340 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHEDMDMH_02341 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHEDMDMH_02342 3.5e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PHEDMDMH_02343 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
PHEDMDMH_02344 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHEDMDMH_02345 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHEDMDMH_02346 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHEDMDMH_02347 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHEDMDMH_02348 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
PHEDMDMH_02349 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
PHEDMDMH_02350 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
PHEDMDMH_02351 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
PHEDMDMH_02352 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
PHEDMDMH_02353 3.17e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHEDMDMH_02354 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
PHEDMDMH_02355 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
PHEDMDMH_02356 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
PHEDMDMH_02357 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
PHEDMDMH_02358 3.04e-29 - - - S - - - Virus attachment protein p12 family
PHEDMDMH_02359 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PHEDMDMH_02360 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PHEDMDMH_02361 1.29e-148 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHEDMDMH_02362 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
PHEDMDMH_02363 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHEDMDMH_02364 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
PHEDMDMH_02365 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_02366 6.35e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02367 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
PHEDMDMH_02368 4.06e-65 - - - - - - - -
PHEDMDMH_02369 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHEDMDMH_02370 1.78e-153 draG - - O - - - ADP-ribosylglycohydrolase
PHEDMDMH_02371 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_02372 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_02373 1.37e-247 - - - S - - - Fn3-like domain
PHEDMDMH_02374 1.65e-80 - - - - - - - -
PHEDMDMH_02375 0.0 - - - - - - - -
PHEDMDMH_02376 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
PHEDMDMH_02377 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_02378 2.71e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
PHEDMDMH_02379 1.96e-137 - - - - - - - -
PHEDMDMH_02380 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
PHEDMDMH_02381 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PHEDMDMH_02382 4.9e-283 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PHEDMDMH_02383 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PHEDMDMH_02384 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PHEDMDMH_02385 5.14e-21 - - - S - - - FRG
PHEDMDMH_02386 4.39e-277 - - - EGP - - - Major Facilitator
PHEDMDMH_02387 1.62e-150 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PHEDMDMH_02388 6.32e-08 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
PHEDMDMH_02389 7.07e-106 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
PHEDMDMH_02390 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHEDMDMH_02391 1.95e-220 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
PHEDMDMH_02392 3.29e-232 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
PHEDMDMH_02393 3.46e-151 - - - L ko:K07497 - ko00000 hmm pf00665
PHEDMDMH_02394 4.83e-36 - - - L ko:K07497 - ko00000 hmm pf00665
PHEDMDMH_02395 8.6e-62 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PHEDMDMH_02396 7.56e-203 ugd 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PHEDMDMH_02397 1.21e-97 - 2.4.1.348 GT4 M ko:K12995 - ko00000,ko01000,ko01003,ko01005 transferase activity, transferring glycosyl groups
PHEDMDMH_02398 8.85e-37 - - - S - - - Glycosyl transferase, family 2
PHEDMDMH_02399 8.38e-91 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
PHEDMDMH_02400 7.56e-183 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PHEDMDMH_02401 2.7e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHEDMDMH_02402 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PHEDMDMH_02403 5.11e-186 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHEDMDMH_02404 1.38e-244 B4168_4126 - - L ko:K07493 - ko00000 Transposase
PHEDMDMH_02405 3.99e-36 - - - - - - - -
PHEDMDMH_02406 1.08e-53 - - - - - - - -
PHEDMDMH_02407 9.87e-148 - - - L - - - PFAM Integrase catalytic region
PHEDMDMH_02408 6.39e-104 - - - L - - - PFAM Integrase catalytic region
PHEDMDMH_02409 8.57e-75 - - - - - - - -
PHEDMDMH_02410 2.83e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
PHEDMDMH_02411 1.32e-115 - - - L ko:K07497 - ko00000 hmm pf00665
PHEDMDMH_02413 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_02415 3.67e-41 - - - - - - - -
PHEDMDMH_02416 1.87e-139 - - - L - - - Integrase
PHEDMDMH_02417 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
PHEDMDMH_02418 1.03e-77 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHEDMDMH_02420 3.81e-35 - - - - - - - -
PHEDMDMH_02422 1.13e-15 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
PHEDMDMH_02423 2.94e-97 repB - - L - - - Initiator Replication protein
PHEDMDMH_02424 3.66e-224 - - - L ko:K07482 - ko00000 Integrase core domain
PHEDMDMH_02425 0.0 - - - L - - - DEAD-like helicases superfamily
PHEDMDMH_02426 1.21e-76 - - - S - - - Protein of unknown function (DUF1722)
PHEDMDMH_02427 4.43e-226 - - - - - - - -
PHEDMDMH_02428 0.0 - - - - - - - -
PHEDMDMH_02429 3.69e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
PHEDMDMH_02430 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PHEDMDMH_02431 1.23e-200 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PHEDMDMH_02432 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHEDMDMH_02433 4.4e-273 pbpX - - V - - - Beta-lactamase
PHEDMDMH_02434 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PHEDMDMH_02435 6.79e-42 - - - - - - - -
PHEDMDMH_02436 2.39e-127 repA - - S - - - Replication initiator protein A
PHEDMDMH_02437 1.47e-70 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
PHEDMDMH_02439 4.97e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_02442 1.48e-45 - - - - - - - -
PHEDMDMH_02444 9.75e-119 llrE - - K - - - Transcriptional regulatory protein, C terminal
PHEDMDMH_02445 1.73e-186 kinE - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PHEDMDMH_02446 3.75e-111 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
PHEDMDMH_02447 1.24e-64 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
PHEDMDMH_02448 2.15e-166 ykoT - - M - - - Glycosyl transferase family 2
PHEDMDMH_02449 7.89e-236 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHEDMDMH_02452 3.69e-38 - - - - - - - -
PHEDMDMH_02453 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHEDMDMH_02454 2.09e-41 - - - - - - - -
PHEDMDMH_02455 1.45e-235 - - - L - - - Psort location Cytoplasmic, score
PHEDMDMH_02456 3.59e-26 - - - - - - - -
PHEDMDMH_02457 1.85e-74 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
PHEDMDMH_02458 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
PHEDMDMH_02459 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PHEDMDMH_02460 1.28e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
PHEDMDMH_02461 1.98e-184 lipA - - I - - - Carboxylesterase family
PHEDMDMH_02462 1.24e-144 - - - K - - - helix_turn_helix, arabinose operon control protein
PHEDMDMH_02463 1.78e-201 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
PHEDMDMH_02464 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
PHEDMDMH_02465 2.07e-123 - - - - - - - -
PHEDMDMH_02466 1.5e-235 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
PHEDMDMH_02467 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
PHEDMDMH_02478 2.48e-66 - - - L ko:K07487 - ko00000 Transposase
PHEDMDMH_02479 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHEDMDMH_02480 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHEDMDMH_02481 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
PHEDMDMH_02482 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PHEDMDMH_02483 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHEDMDMH_02484 1.56e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PHEDMDMH_02485 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHEDMDMH_02486 4.71e-171 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
PHEDMDMH_02487 0.0 ymfH - - S - - - Peptidase M16
PHEDMDMH_02488 5.88e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
PHEDMDMH_02489 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PHEDMDMH_02490 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PHEDMDMH_02491 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02492 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
PHEDMDMH_02493 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
PHEDMDMH_02494 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PHEDMDMH_02495 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
PHEDMDMH_02496 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PHEDMDMH_02497 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
PHEDMDMH_02498 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
PHEDMDMH_02499 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PHEDMDMH_02500 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHEDMDMH_02501 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PHEDMDMH_02502 6.39e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
PHEDMDMH_02503 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHEDMDMH_02504 2.59e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
PHEDMDMH_02506 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHEDMDMH_02507 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PHEDMDMH_02508 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHEDMDMH_02509 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
PHEDMDMH_02510 4e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
PHEDMDMH_02511 2.6e-141 - - - S - - - Protein of unknown function (DUF1648)
PHEDMDMH_02512 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_02513 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
PHEDMDMH_02514 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
PHEDMDMH_02515 1.34e-52 - - - - - - - -
PHEDMDMH_02516 2.37e-107 uspA - - T - - - universal stress protein
PHEDMDMH_02517 8.1e-261 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
PHEDMDMH_02518 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
PHEDMDMH_02519 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
PHEDMDMH_02520 8.91e-271 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PHEDMDMH_02521 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PHEDMDMH_02522 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
PHEDMDMH_02523 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
PHEDMDMH_02524 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PHEDMDMH_02525 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_02526 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHEDMDMH_02527 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
PHEDMDMH_02528 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PHEDMDMH_02529 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
PHEDMDMH_02530 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
PHEDMDMH_02531 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
PHEDMDMH_02532 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHEDMDMH_02533 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHEDMDMH_02534 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PHEDMDMH_02535 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHEDMDMH_02536 1.07e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHEDMDMH_02537 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHEDMDMH_02538 5.83e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHEDMDMH_02539 7.68e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHEDMDMH_02540 3.66e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHEDMDMH_02541 6.85e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PHEDMDMH_02542 1.44e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
PHEDMDMH_02543 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHEDMDMH_02544 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHEDMDMH_02545 7.28e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHEDMDMH_02546 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHEDMDMH_02547 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHEDMDMH_02548 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PHEDMDMH_02549 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
PHEDMDMH_02550 1.06e-174 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
PHEDMDMH_02551 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PHEDMDMH_02552 2.65e-245 ampC - - V - - - Beta-lactamase
PHEDMDMH_02553 2.1e-41 - - - - - - - -
PHEDMDMH_02554 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PHEDMDMH_02555 1.33e-77 - - - - - - - -
PHEDMDMH_02556 5.37e-182 - - - - - - - -
PHEDMDMH_02557 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
PHEDMDMH_02558 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02559 5.63e-89 yxeA - - S - - - Protein of unknown function (DUF1093)
PHEDMDMH_02560 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
PHEDMDMH_02563 8.08e-40 - - - - - - - -
PHEDMDMH_02566 7.78e-76 - - - - - - - -
PHEDMDMH_02567 1.62e-53 - - - S - - - Phage gp6-like head-tail connector protein
PHEDMDMH_02568 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
PHEDMDMH_02569 1.84e-261 - - - S - - - Phage portal protein
PHEDMDMH_02570 0.000349 - - - - - - - -
PHEDMDMH_02571 0.0 terL - - S - - - overlaps another CDS with the same product name
PHEDMDMH_02572 6.36e-108 - - - L - - - overlaps another CDS with the same product name
PHEDMDMH_02573 2.59e-89 - - - L - - - HNH endonuclease
PHEDMDMH_02574 7.63e-65 - - - S - - - Head-tail joining protein
PHEDMDMH_02576 3.36e-96 - - - - - - - -
PHEDMDMH_02577 0.0 - - - S - - - Virulence-associated protein E
PHEDMDMH_02578 9.72e-184 - - - L - - - DNA replication protein
PHEDMDMH_02579 3.18e-41 - - - - - - - -
PHEDMDMH_02581 3.96e-13 - - - - - - - -
PHEDMDMH_02583 1.1e-06 - - - K ko:K07727 - ko00000,ko03000 transcriptional regulator
PHEDMDMH_02584 2.54e-289 - - - L - - - Belongs to the 'phage' integrase family
PHEDMDMH_02585 1.28e-51 - - - - - - - -
PHEDMDMH_02586 1.09e-56 - - - - - - - -
PHEDMDMH_02587 1.27e-109 - - - K - - - MarR family
PHEDMDMH_02588 0.0 - - - D - - - nuclear chromosome segregation
PHEDMDMH_02589 0.0 inlJ - - M - - - MucBP domain
PHEDMDMH_02590 6.58e-24 - - - - - - - -
PHEDMDMH_02591 3.26e-24 - - - - - - - -
PHEDMDMH_02592 1.56e-22 - - - - - - - -
PHEDMDMH_02593 1.07e-26 - - - - - - - -
PHEDMDMH_02594 9.35e-24 - - - - - - - -
PHEDMDMH_02595 9.35e-24 - - - - - - - -
PHEDMDMH_02596 2.16e-26 - - - - - - - -
PHEDMDMH_02597 4.63e-24 - - - - - - - -
PHEDMDMH_02598 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
PHEDMDMH_02599 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHEDMDMH_02600 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02601 2.1e-33 - - - - - - - -
PHEDMDMH_02602 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PHEDMDMH_02603 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
PHEDMDMH_02604 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
PHEDMDMH_02605 0.0 yclK - - T - - - Histidine kinase
PHEDMDMH_02606 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
PHEDMDMH_02607 3.51e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
PHEDMDMH_02608 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
PHEDMDMH_02609 1.26e-218 - - - EG - - - EamA-like transporter family
PHEDMDMH_02611 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
PHEDMDMH_02612 1.31e-64 - - - - - - - -
PHEDMDMH_02613 1.13e-272 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
PHEDMDMH_02614 8.05e-178 - - - F - - - NUDIX domain
PHEDMDMH_02615 2.68e-32 - - - - - - - -
PHEDMDMH_02617 2e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
PHEDMDMH_02618 2.47e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
PHEDMDMH_02619 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
PHEDMDMH_02620 2.29e-48 - - - - - - - -
PHEDMDMH_02621 1.11e-45 - - - - - - - -
PHEDMDMH_02622 2.58e-274 - - - T - - - diguanylate cyclase
PHEDMDMH_02623 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
PHEDMDMH_02624 4.22e-34 - - - - - - - -
PHEDMDMH_02625 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
PHEDMDMH_02626 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
PHEDMDMH_02627 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
PHEDMDMH_02628 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
PHEDMDMH_02629 1.29e-31 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
PHEDMDMH_02630 4.05e-170 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
PHEDMDMH_02631 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
PHEDMDMH_02632 1.38e-45 - - - - - - - -
PHEDMDMH_02634 4.84e-38 - - - S - - - Psort location CytoplasmicMembrane, score
PHEDMDMH_02635 8.18e-33 mpr - - E - - - Trypsin-like serine protease
PHEDMDMH_02636 4.51e-46 - - - L - - - 4.5 Transposon and IS
PHEDMDMH_02637 4.68e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
PHEDMDMH_02638 8.83e-57 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
PHEDMDMH_02639 1.47e-07 - - - L - - - Integrase
PHEDMDMH_02641 7.21e-08 - - - L - - - Transposase and inactivated derivatives, IS30 family
PHEDMDMH_02642 1.17e-125 tnp1216 - - L ko:K07498 - ko00000 DDE domain
PHEDMDMH_02643 7.51e-61 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PHEDMDMH_02644 4.33e-190 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_02646 5.09e-69 - - - - - - - -
PHEDMDMH_02647 1.8e-236 repA - - S - - - Replication initiator protein A
PHEDMDMH_02648 2.83e-58 - - - L - - - Addiction module antitoxin, RelB DinJ family
PHEDMDMH_02649 2.73e-38 - - - - - - - -
PHEDMDMH_02650 1.4e-163 - - - S - - - protein conserved in bacteria
PHEDMDMH_02651 5.12e-56 - - - - - - - -
PHEDMDMH_02652 4.76e-88 - - - L - - - manually curated
PHEDMDMH_02653 4.05e-130 repE - - K - - - Primase C terminal 1 (PriCT-1)
PHEDMDMH_02654 2.02e-110 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_02657 2.65e-73 - - - L - - - recombinase activity
PHEDMDMH_02658 5.53e-90 - - - S - - - Domain of unknown function (DUF4767)
PHEDMDMH_02659 6.35e-69 - - - - - - - -
PHEDMDMH_02660 8.49e-60 - - - S - - - MORN repeat
PHEDMDMH_02661 0.0 XK27_09800 - - I - - - Acyltransferase family
PHEDMDMH_02662 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
PHEDMDMH_02663 1.95e-116 - - - - - - - -
PHEDMDMH_02664 5.74e-32 - - - - - - - -
PHEDMDMH_02665 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
PHEDMDMH_02666 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
PHEDMDMH_02667 3.42e-141 - - - - - - - -
PHEDMDMH_02668 2.27e-140 - - - L - - - Integrase
PHEDMDMH_02669 1.02e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
PHEDMDMH_02670 2.08e-77 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHEDMDMH_02671 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
PHEDMDMH_02674 4.6e-102 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PHEDMDMH_02675 4.3e-55 - - - - - - - -
PHEDMDMH_02677 2.61e-88 - - - - - - - -
PHEDMDMH_02679 7.79e-97 - - - S - - - Initiator Replication protein
PHEDMDMH_02680 3.89e-132 tnpR - - L - - - Resolvase, N terminal domain
PHEDMDMH_02681 3.13e-238 - - - C - - - FMN_bind
PHEDMDMH_02682 2.45e-49 - - - K - - - LysR substrate binding domain
PHEDMDMH_02683 2.96e-77 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHEDMDMH_02684 0.0 ybeC - - E - - - amino acid
PHEDMDMH_02685 7.04e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
PHEDMDMH_02686 1.36e-132 tnpR - - L - - - Resolvase, N terminal domain
PHEDMDMH_02688 1.1e-108 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
PHEDMDMH_02689 4.55e-126 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PHEDMDMH_02690 1.54e-141 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PHEDMDMH_02691 2.97e-234 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
PHEDMDMH_02692 1.97e-87 - - - K - - - Transcriptional regulator
PHEDMDMH_02693 1.11e-205 - - - S - - - EDD domain protein, DegV family
PHEDMDMH_02694 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
PHEDMDMH_02695 1.96e-168 - - - S - - - Protein of unknown function (DUF975)
PHEDMDMH_02696 2.29e-36 - - - - - - - -
PHEDMDMH_02697 2.37e-65 - - - - - - - -
PHEDMDMH_02698 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
PHEDMDMH_02699 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
PHEDMDMH_02701 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
PHEDMDMH_02702 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
PHEDMDMH_02703 1.05e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
PHEDMDMH_02704 7.45e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
PHEDMDMH_02705 2.79e-181 - - - - - - - -
PHEDMDMH_02706 7.79e-78 - - - - - - - -
PHEDMDMH_02707 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PHEDMDMH_02708 8.23e-291 - - - - - - - -
PHEDMDMH_02709 2.13e-151 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
PHEDMDMH_02710 8.6e-31 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
PHEDMDMH_02711 1.17e-181 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
PHEDMDMH_02712 2.89e-273 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHEDMDMH_02713 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHEDMDMH_02714 3.29e-121 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PHEDMDMH_02715 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PHEDMDMH_02716 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
PHEDMDMH_02717 7.27e-57 - - - - - - - -
PHEDMDMH_02718 1.18e-310 - - - M - - - Glycosyl transferase family group 2
PHEDMDMH_02719 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHEDMDMH_02720 4.19e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
PHEDMDMH_02721 1.07e-43 - - - S - - - YozE SAM-like fold
PHEDMDMH_02722 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHEDMDMH_02723 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PHEDMDMH_02724 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
PHEDMDMH_02725 5.43e-228 - - - K - - - Transcriptional regulator
PHEDMDMH_02726 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHEDMDMH_02727 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHEDMDMH_02728 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHEDMDMH_02729 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PHEDMDMH_02730 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PHEDMDMH_02731 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PHEDMDMH_02732 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
PHEDMDMH_02733 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PHEDMDMH_02734 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHEDMDMH_02735 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
PHEDMDMH_02736 1.01e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHEDMDMH_02737 2.25e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHEDMDMH_02739 5.13e-292 XK27_05470 - - E - - - Methionine synthase
PHEDMDMH_02740 7.05e-219 cpsY - - K - - - Transcriptional regulator, LysR family
PHEDMDMH_02741 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
PHEDMDMH_02742 3.53e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
PHEDMDMH_02743 1.43e-251 XK27_00915 - - C - - - Luciferase-like monooxygenase
PHEDMDMH_02744 0.0 qacA - - EGP - - - Major Facilitator
PHEDMDMH_02745 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PHEDMDMH_02746 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
PHEDMDMH_02747 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
PHEDMDMH_02748 5.66e-207 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
PHEDMDMH_02749 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
PHEDMDMH_02750 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHEDMDMH_02751 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHEDMDMH_02752 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02753 6.46e-109 - - - - - - - -
PHEDMDMH_02754 1.27e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHEDMDMH_02755 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHEDMDMH_02756 7.48e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
PHEDMDMH_02757 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
PHEDMDMH_02758 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHEDMDMH_02759 4.84e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PHEDMDMH_02760 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PHEDMDMH_02761 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PHEDMDMH_02762 1.25e-39 - - - M - - - Lysin motif
PHEDMDMH_02763 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
PHEDMDMH_02764 1.72e-245 - - - S - - - Helix-turn-helix domain
PHEDMDMH_02765 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHEDMDMH_02766 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PHEDMDMH_02767 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHEDMDMH_02768 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHEDMDMH_02769 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHEDMDMH_02770 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
PHEDMDMH_02771 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
PHEDMDMH_02772 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
PHEDMDMH_02773 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PHEDMDMH_02774 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHEDMDMH_02775 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PHEDMDMH_02776 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
PHEDMDMH_02778 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHEDMDMH_02779 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PHEDMDMH_02780 1.09e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHEDMDMH_02781 6.85e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PHEDMDMH_02782 1.75e-295 - - - M - - - O-Antigen ligase
PHEDMDMH_02783 5.09e-165 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
PHEDMDMH_02784 2.08e-213 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_02785 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PHEDMDMH_02786 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHEDMDMH_02787 1.06e-69 - - - P - - - Rhodanese Homology Domain
PHEDMDMH_02788 6.11e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
PHEDMDMH_02789 1.93e-266 - - - - - - - -
PHEDMDMH_02790 4.8e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
PHEDMDMH_02791 1.02e-230 - - - C - - - Zinc-binding dehydrogenase
PHEDMDMH_02792 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
PHEDMDMH_02793 1.04e-308 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHEDMDMH_02794 1.32e-306 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
PHEDMDMH_02795 4.38e-102 - - - K - - - Transcriptional regulator
PHEDMDMH_02796 7.53e-264 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
PHEDMDMH_02797 4.03e-245 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHEDMDMH_02798 1.64e-126 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHEDMDMH_02799 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
PHEDMDMH_02800 1.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
PHEDMDMH_02801 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
PHEDMDMH_02802 6.34e-90 - - - S - - - Protein of unknown function (DUF1722)
PHEDMDMH_02803 8.09e-146 - - - GM - - - epimerase
PHEDMDMH_02804 0.0 - - - S - - - Zinc finger, swim domain protein
PHEDMDMH_02805 1.51e-105 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_02806 5.58e-274 - - - S - - - membrane
PHEDMDMH_02807 3.79e-39 - - - - - - - -
PHEDMDMH_02808 3.7e-164 - - - L ko:K07498 - ko00000 Transposase IS66 family
PHEDMDMH_02809 3.06e-35 - - - L ko:K07483 - ko00000 Homeodomain-like domain
PHEDMDMH_02810 1.91e-91 - - - - - - - -
PHEDMDMH_02811 4.59e-58 - - - - - - - -
PHEDMDMH_02812 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
PHEDMDMH_02814 2.34e-90 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
PHEDMDMH_02815 4.36e-148 - - - EGP - - - Transmembrane secretion effector
PHEDMDMH_02816 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
PHEDMDMH_02817 3.26e-262 - - - EGP - - - Transmembrane secretion effector
PHEDMDMH_02818 3.18e-246 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHEDMDMH_02819 0.0 eriC - - P ko:K03281 - ko00000 chloride
PHEDMDMH_02820 7.12e-36 - - - - - - - -
PHEDMDMH_02821 9.04e-155 - - - P - - - Major Facilitator Superfamily
PHEDMDMH_02822 5.42e-142 - - - GK - - - ROK family
PHEDMDMH_02823 1.33e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PHEDMDMH_02824 3.4e-90 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PHEDMDMH_02825 1.97e-189 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_02826 1.37e-62 - - - S - - - Family of unknown function (DUF5388)
PHEDMDMH_02829 5.54e-08 - - - - - - - -
PHEDMDMH_02830 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
PHEDMDMH_02831 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
PHEDMDMH_02832 1.74e-25 - - - - - - - -
PHEDMDMH_02833 8.03e-160 - - - S - - - Fic/DOC family
PHEDMDMH_02834 4.45e-38 - - - - - - - -
PHEDMDMH_02835 1.58e-59 - - - L - - - Transposase DDE domain
PHEDMDMH_02836 3.98e-198 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
PHEDMDMH_02837 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PHEDMDMH_02838 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_02842 1.03e-314 yhgE - - V ko:K01421 - ko00000 domain protein
PHEDMDMH_02843 3.01e-124 - - - K - - - Transcriptional regulator (TetR family)
PHEDMDMH_02844 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_02845 4.88e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
PHEDMDMH_02846 1.34e-132 yokL3 - - J - - - Acetyltransferase (GNAT) domain
PHEDMDMH_02847 1.24e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHEDMDMH_02848 3.27e-171 - - - M - - - Phosphotransferase enzyme family
PHEDMDMH_02849 3.18e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_02850 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
PHEDMDMH_02851 1.9e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
PHEDMDMH_02852 0.0 - - - S - - - Predicted membrane protein (DUF2207)
PHEDMDMH_02853 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
PHEDMDMH_02854 9.48e-265 - - - EGP - - - Major facilitator Superfamily
PHEDMDMH_02855 7.97e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
PHEDMDMH_02856 1.45e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
PHEDMDMH_02857 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
PHEDMDMH_02858 2.85e-206 - - - I - - - alpha/beta hydrolase fold
PHEDMDMH_02859 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
PHEDMDMH_02860 0.0 - - - - - - - -
PHEDMDMH_02861 2e-52 - - - S - - - Cytochrome B5
PHEDMDMH_02862 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHEDMDMH_02863 1.11e-65 - - - T - - - Diguanylate cyclase, GGDEF domain
PHEDMDMH_02864 5.08e-194 - - - T - - - Diguanylate cyclase, GGDEF domain
PHEDMDMH_02865 1.63e-162 - - - T - - - Putative diguanylate phosphodiesterase
PHEDMDMH_02866 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHEDMDMH_02867 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
PHEDMDMH_02868 1.56e-108 - - - - - - - -
PHEDMDMH_02869 6.98e-95 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHEDMDMH_02870 3.08e-241 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHEDMDMH_02871 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHEDMDMH_02872 7.16e-30 - - - - - - - -
PHEDMDMH_02873 1.84e-134 - - - - - - - -
PHEDMDMH_02874 3.46e-210 - - - K - - - LysR substrate binding domain
PHEDMDMH_02875 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
PHEDMDMH_02876 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PHEDMDMH_02877 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PHEDMDMH_02878 1.61e-183 - - - S - - - zinc-ribbon domain
PHEDMDMH_02880 4.29e-50 - - - - - - - -
PHEDMDMH_02881 1.48e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
PHEDMDMH_02882 2.35e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
PHEDMDMH_02883 0.0 - - - I - - - acetylesterase activity
PHEDMDMH_02884 6.55e-295 - - - M - - - Collagen binding domain
PHEDMDMH_02885 8.08e-205 yicL - - EG - - - EamA-like transporter family
PHEDMDMH_02886 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
PHEDMDMH_02887 1.44e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
PHEDMDMH_02888 4.68e-141 - - - K - - - Transcriptional regulator C-terminal region
PHEDMDMH_02889 1.85e-51 - - - K - - - HxlR-like helix-turn-helix
PHEDMDMH_02890 4.54e-208 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
PHEDMDMH_02891 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
PHEDMDMH_02892 9.86e-117 - - - - - - - -
PHEDMDMH_02893 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PHEDMDMH_02894 7.39e-121 - - - K - - - Transcriptional regulator, MarR family
PHEDMDMH_02895 5.85e-204 ccpB - - K - - - lacI family
PHEDMDMH_02896 2.21e-154 yceE - - S - - - haloacid dehalogenase-like hydrolase
PHEDMDMH_02897 3.29e-153 ydgI3 - - C - - - Nitroreductase family
PHEDMDMH_02898 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
PHEDMDMH_02899 4.21e-150 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PHEDMDMH_02900 1.01e-198 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PHEDMDMH_02901 5.98e-217 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_02902 0.0 - - - - - - - -
PHEDMDMH_02903 4.71e-81 - - - - - - - -
PHEDMDMH_02904 9.55e-243 - - - S - - - Cell surface protein
PHEDMDMH_02905 1.48e-136 - - - S - - - WxL domain surface cell wall-binding
PHEDMDMH_02906 5.06e-82 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PHEDMDMH_02907 1.09e-42 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PHEDMDMH_02908 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
PHEDMDMH_02909 1.74e-178 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
PHEDMDMH_02910 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
PHEDMDMH_02911 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
PHEDMDMH_02912 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
PHEDMDMH_02914 1.15e-43 - - - - - - - -
PHEDMDMH_02915 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
PHEDMDMH_02916 2.88e-106 gtcA3 - - S - - - GtrA-like protein
PHEDMDMH_02917 1.39e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
PHEDMDMH_02918 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PHEDMDMH_02919 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
PHEDMDMH_02920 7.03e-62 - - - - - - - -
PHEDMDMH_02921 1.81e-150 - - - S - - - SNARE associated Golgi protein
PHEDMDMH_02922 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
PHEDMDMH_02923 7.89e-124 - - - P - - - Cadmium resistance transporter
PHEDMDMH_02924 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PHEDMDMH_02925 7.38e-90 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
PHEDMDMH_02926 1.8e-285 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
PHEDMDMH_02927 2.03e-84 - - - - - - - -
PHEDMDMH_02928 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
PHEDMDMH_02929 1.21e-73 - - - - - - - -
PHEDMDMH_02930 1.24e-194 - - - K - - - Helix-turn-helix domain
PHEDMDMH_02931 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHEDMDMH_02932 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PHEDMDMH_02933 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHEDMDMH_02934 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PHEDMDMH_02935 7.8e-238 - - - GM - - - Male sterility protein
PHEDMDMH_02936 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_02937 2.18e-99 - - - M - - - LysM domain
PHEDMDMH_02938 1.44e-128 - - - M - - - Lysin motif
PHEDMDMH_02939 1.4e-138 - - - S - - - SdpI/YhfL protein family
PHEDMDMH_02940 1.58e-72 nudA - - S - - - ASCH
PHEDMDMH_02941 2.74e-210 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PHEDMDMH_02942 1.41e-118 - - - - - - - -
PHEDMDMH_02943 6.68e-156 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
PHEDMDMH_02944 1.22e-272 - - - T - - - diguanylate cyclase
PHEDMDMH_02945 4.65e-91 - - - S - - - Psort location Cytoplasmic, score
PHEDMDMH_02946 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
PHEDMDMH_02947 1.43e-57 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
PHEDMDMH_02948 6.88e-151 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
PHEDMDMH_02949 5.36e-38 - - - - - - - -
PHEDMDMH_02950 1e-62 adhR - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_02951 1.58e-47 - - - C - - - Flavodoxin
PHEDMDMH_02952 1.2e-208 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
PHEDMDMH_02953 2.62e-173 - - - C - - - Aldo/keto reductase family
PHEDMDMH_02954 7.53e-102 - - - GM - - - NmrA-like family
PHEDMDMH_02955 1.91e-44 - - - C - - - Flavodoxin
PHEDMDMH_02956 8.4e-15 - - - L ko:K07487 - ko00000 Transposase
PHEDMDMH_02957 3.33e-23 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
PHEDMDMH_02958 4.2e-306 xylP - - G - - - MFS/sugar transport protein
PHEDMDMH_02959 8.99e-133 - - - - - - - -
PHEDMDMH_02960 1.24e-162 tnp1216 - - L ko:K07498 - ko00000 DDE domain
PHEDMDMH_02961 1.35e-214 - - - L - - - Replication protein
PHEDMDMH_02963 4.97e-174 mob - - D - - - Plasmid recombination enzyme
PHEDMDMH_02964 2.38e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 COG1136 ABC-type antimicrobial peptide transport system, ATPase component
PHEDMDMH_02965 6.84e-233 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
PHEDMDMH_02966 2.71e-33 - - - L ko:K07483 - ko00000 Transposase
PHEDMDMH_02967 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
PHEDMDMH_02968 7.11e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PHEDMDMH_02969 1.45e-253 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-type multidrug transport system, permease component
PHEDMDMH_02970 1.44e-150 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_02971 1.89e-58 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHEDMDMH_02972 3.07e-218 - - - L - - - PFAM Integrase catalytic region
PHEDMDMH_02973 8.83e-06 - - - - - - - -
PHEDMDMH_02974 2.21e-84 - - - D - - - AAA domain
PHEDMDMH_02975 3.42e-41 - - - L - - - Integrase
PHEDMDMH_02977 4.18e-39 - - - - - - - -
PHEDMDMH_02978 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
PHEDMDMH_02979 1.76e-127 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHEDMDMH_02981 2.34e-35 - - - - - - - -
PHEDMDMH_02983 5.86e-148 - - - S - - - Plasmid replication protein
PHEDMDMH_02984 4.13e-104 - - - K - - - Transcriptional regulator
PHEDMDMH_02985 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PHEDMDMH_02986 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
PHEDMDMH_02987 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
PHEDMDMH_02988 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PHEDMDMH_02989 1.32e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PHEDMDMH_02990 9.05e-55 - - - - - - - -
PHEDMDMH_02991 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
PHEDMDMH_02992 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
PHEDMDMH_02993 9.95e-211 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PHEDMDMH_02994 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PHEDMDMH_02995 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
PHEDMDMH_02996 1.86e-242 - - - - - - - -
PHEDMDMH_02997 1.89e-277 yibE - - S - - - overlaps another CDS with the same product name
PHEDMDMH_02998 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
PHEDMDMH_02999 1.37e-131 - - - K - - - FR47-like protein
PHEDMDMH_03000 1.24e-155 gpm5 - - G - - - Phosphoglycerate mutase family
PHEDMDMH_03001 2.74e-63 - - - - - - - -
PHEDMDMH_03002 2.98e-246 - - - I - - - alpha/beta hydrolase fold
PHEDMDMH_03003 0.0 xylP2 - - G - - - symporter
PHEDMDMH_03004 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHEDMDMH_03005 2.42e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
PHEDMDMH_03006 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PHEDMDMH_03007 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
PHEDMDMH_03008 1.43e-155 azlC - - E - - - branched-chain amino acid
PHEDMDMH_03009 1.75e-47 - - - K - - - MerR HTH family regulatory protein
PHEDMDMH_03010 1.46e-170 - - - - - - - -
PHEDMDMH_03011 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
PHEDMDMH_03012 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
PHEDMDMH_03013 7.79e-112 - - - K - - - MerR HTH family regulatory protein
PHEDMDMH_03014 1.36e-77 - - - - - - - -
PHEDMDMH_03015 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
PHEDMDMH_03016 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
PHEDMDMH_03017 4.6e-169 - - - S - - - Putative threonine/serine exporter
PHEDMDMH_03018 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
PHEDMDMH_03019 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PHEDMDMH_03020 4.15e-153 - - - I - - - phosphatase
PHEDMDMH_03021 3.88e-198 - - - I - - - alpha/beta hydrolase fold
PHEDMDMH_03022 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PHEDMDMH_03023 9.82e-118 - - - K - - - Transcriptional regulator
PHEDMDMH_03024 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PHEDMDMH_03025 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
PHEDMDMH_03026 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PHEDMDMH_03027 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
PHEDMDMH_03028 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHEDMDMH_03036 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PHEDMDMH_03037 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHEDMDMH_03038 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
PHEDMDMH_03039 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHEDMDMH_03040 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHEDMDMH_03041 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHEDMDMH_03042 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHEDMDMH_03043 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHEDMDMH_03044 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PHEDMDMH_03045 2.51e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHEDMDMH_03046 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PHEDMDMH_03047 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHEDMDMH_03048 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHEDMDMH_03049 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHEDMDMH_03050 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHEDMDMH_03051 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHEDMDMH_03052 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHEDMDMH_03053 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PHEDMDMH_03054 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHEDMDMH_03055 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHEDMDMH_03056 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHEDMDMH_03057 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHEDMDMH_03058 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHEDMDMH_03059 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHEDMDMH_03060 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHEDMDMH_03061 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHEDMDMH_03062 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PHEDMDMH_03063 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
PHEDMDMH_03064 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHEDMDMH_03065 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHEDMDMH_03066 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHEDMDMH_03067 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHEDMDMH_03068 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHEDMDMH_03069 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHEDMDMH_03070 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PHEDMDMH_03071 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PHEDMDMH_03072 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
PHEDMDMH_03073 5.37e-112 - - - S - - - NusG domain II
PHEDMDMH_03074 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PHEDMDMH_03075 3.19e-194 - - - S - - - FMN_bind
PHEDMDMH_03076 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHEDMDMH_03077 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHEDMDMH_03078 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHEDMDMH_03079 2.39e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHEDMDMH_03080 8.77e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHEDMDMH_03081 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHEDMDMH_03082 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PHEDMDMH_03083 4.92e-209 yitS - - S - - - Uncharacterised protein, DegV family COG1307
PHEDMDMH_03084 2.46e-235 - - - S - - - Membrane
PHEDMDMH_03085 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
PHEDMDMH_03086 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PHEDMDMH_03087 2.25e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHEDMDMH_03088 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
PHEDMDMH_03089 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PHEDMDMH_03090 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PHEDMDMH_03091 4.33e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
PHEDMDMH_03092 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
PHEDMDMH_03093 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
PHEDMDMH_03094 1.28e-253 - - - K - - - Helix-turn-helix domain
PHEDMDMH_03095 4.49e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PHEDMDMH_03096 8.31e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PHEDMDMH_03097 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
PHEDMDMH_03098 1.73e-221 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PHEDMDMH_03099 1.18e-66 - - - - - - - -
PHEDMDMH_03100 3.75e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PHEDMDMH_03101 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PHEDMDMH_03102 8.69e-230 citR - - K - - - sugar-binding domain protein
PHEDMDMH_03103 3.88e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
PHEDMDMH_03104 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PHEDMDMH_03105 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
PHEDMDMH_03106 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
PHEDMDMH_03107 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
PHEDMDMH_03109 1.95e-45 ydaT - - - - - - -
PHEDMDMH_03110 4.25e-198 - - - L ko:K07482 - ko00000 Integrase core domain
PHEDMDMH_03112 2.03e-31 - - - S - - - Family of unknown function (DUF5388)
PHEDMDMH_03113 1.18e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
PHEDMDMH_03114 3.3e-261 butB 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
PHEDMDMH_03115 2.75e-40 - - - - - - - -
PHEDMDMH_03116 1.75e-124 - - - S - - - Protease prsW family
PHEDMDMH_03117 3.24e-230 - - - U - - - Relaxase/Mobilisation nuclease domain
PHEDMDMH_03120 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PHEDMDMH_03121 1.07e-213 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
PHEDMDMH_03122 4.94e-197 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHEDMDMH_03123 1.94e-149 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHEDMDMH_03124 6.75e-157 - - - - - - - -
PHEDMDMH_03125 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHEDMDMH_03126 0.0 mdr - - EGP - - - Major Facilitator
PHEDMDMH_03127 1.63e-288 - - - N - - - Cell shape-determining protein MreB
PHEDMDMH_03128 0.0 - - - S - - - Pfam Methyltransferase
PHEDMDMH_03129 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHEDMDMH_03130 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PHEDMDMH_03131 9.32e-40 - - - - - - - -
PHEDMDMH_03132 3.03e-122 mraW1 - - J - - - Putative rRNA methylase
PHEDMDMH_03133 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PHEDMDMH_03134 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PHEDMDMH_03135 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
PHEDMDMH_03136 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PHEDMDMH_03137 3.03e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHEDMDMH_03138 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
PHEDMDMH_03139 9.54e-109 - - - T - - - Belongs to the universal stress protein A family
PHEDMDMH_03140 1.45e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
PHEDMDMH_03141 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PHEDMDMH_03142 2.51e-192 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
PHEDMDMH_03143 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PHEDMDMH_03144 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PHEDMDMH_03145 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
PHEDMDMH_03146 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHEDMDMH_03147 1.48e-315 XK27_06930 - - V ko:K01421 - ko00000 domain protein
PHEDMDMH_03149 3.03e-135 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
PHEDMDMH_03150 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PHEDMDMH_03151 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
PHEDMDMH_03153 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHEDMDMH_03154 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
PHEDMDMH_03155 1.64e-151 - - - GM - - - NAD(P)H-binding
PHEDMDMH_03156 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PHEDMDMH_03157 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
PHEDMDMH_03158 7.83e-140 - - - - - - - -
PHEDMDMH_03159 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PHEDMDMH_03160 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PHEDMDMH_03161 5.37e-74 - - - - - - - -
PHEDMDMH_03162 4.56e-78 - - - - - - - -
PHEDMDMH_03163 3.54e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
PHEDMDMH_03164 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
PHEDMDMH_03165 3.59e-118 - - - - - - - -
PHEDMDMH_03166 7.12e-62 - - - - - - - -
PHEDMDMH_03167 0.0 uvrA2 - - L - - - ABC transporter
PHEDMDMH_03169 4.19e-118 int3 - - L - - - Belongs to the 'phage' integrase family
PHEDMDMH_03170 1.39e-296 yeeA - - V - - - Type II restriction enzyme, methylase subunits
PHEDMDMH_03175 5.72e-27 - - - - - - - -
PHEDMDMH_03176 1.53e-11 - - - - - - - -
PHEDMDMH_03177 2.52e-35 - - - S - - - Domain of unknown function (DUF771)
PHEDMDMH_03182 1.29e-52 - - - S - - - Siphovirus Gp157
PHEDMDMH_03183 3.5e-217 - - - S - - - helicase activity
PHEDMDMH_03184 2.01e-93 - - - L - - - AAA domain
PHEDMDMH_03185 3.18e-28 - - - - - - - -
PHEDMDMH_03187 1.55e-95 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
PHEDMDMH_03188 9.08e-166 - - - S ko:K06919 - ko00000 Virulence-associated protein E
PHEDMDMH_03189 1.74e-48 - - - S - - - hydrolase activity, acting on ester bonds
PHEDMDMH_03190 0.000459 - - - - - - - -
PHEDMDMH_03191 1.45e-51 - - - S - - - DNA N-6-adenine-methyltransferase (Dam)
PHEDMDMH_03193 1.87e-43 - - - - - - - -
PHEDMDMH_03197 2.4e-32 - - - V - - - HNH nucleases
PHEDMDMH_03200 3.41e-13 - - - - - - - -
PHEDMDMH_03201 1.56e-211 - - - S - - - Terminase
PHEDMDMH_03202 1.24e-128 - - - S - - - Phage portal protein
PHEDMDMH_03203 2.45e-72 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
PHEDMDMH_03204 5.26e-134 - - - S - - - Phage capsid family
PHEDMDMH_03205 3.26e-19 - - - - - - - -
PHEDMDMH_03206 2.14e-32 - - - - - - - -
PHEDMDMH_03207 1.12e-32 - - - - - - - -
PHEDMDMH_03208 4.57e-29 - - - - - - - -
PHEDMDMH_03209 1.07e-43 - - - S - - - Phage tail tube protein
PHEDMDMH_03211 1.6e-188 - - - L - - - Phage tail tape measure protein TP901
PHEDMDMH_03213 9.18e-136 - - - LM - - - DNA recombination
PHEDMDMH_03214 9.48e-24 - - - S - - - Protein of unknown function (DUF1617)
PHEDMDMH_03216 1.94e-60 - - - - - - - -
PHEDMDMH_03218 5.04e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
PHEDMDMH_03219 4.18e-137 - - - M - - - Glycosyl hydrolases family 25
PHEDMDMH_03221 4.29e-87 - - - - - - - -
PHEDMDMH_03222 9.03e-16 - - - - - - - -
PHEDMDMH_03223 1.12e-236 - - - - - - - -
PHEDMDMH_03224 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
PHEDMDMH_03225 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
PHEDMDMH_03226 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PHEDMDMH_03227 1.3e-111 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHEDMDMH_03228 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHEDMDMH_03229 0.0 - - - S - - - Protein conserved in bacteria
PHEDMDMH_03230 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
PHEDMDMH_03231 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PHEDMDMH_03232 2.54e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
PHEDMDMH_03233 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
PHEDMDMH_03234 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
PHEDMDMH_03236 0.000793 - - - - - - - -
PHEDMDMH_03237 2.22e-169 - - - L - - - Helix-turn-helix domain
PHEDMDMH_03238 3.54e-211 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
PHEDMDMH_03239 3.32e-101 repA - - S - - - Replication initiator protein A
PHEDMDMH_03240 1.15e-57 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
PHEDMDMH_03241 3.11e-218 - - - L ko:K07497 - ko00000 Integrase core domain
PHEDMDMH_03242 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
PHEDMDMH_03243 6.67e-76 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PHEDMDMH_03244 2.06e-234 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
PHEDMDMH_03245 1e-186 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
PHEDMDMH_03246 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHEDMDMH_03247 3.16e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)