ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KEHGHMLM_00001 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
KEHGHMLM_00009 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KEHGHMLM_00010 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KEHGHMLM_00011 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
KEHGHMLM_00012 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KEHGHMLM_00013 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KEHGHMLM_00014 2.81e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
KEHGHMLM_00015 7.75e-262 cotI - - S ko:K06331 - ko00000 Spore coat protein
KEHGHMLM_00016 2.04e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
KEHGHMLM_00017 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
KEHGHMLM_00019 2.14e-299 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
KEHGHMLM_00020 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
KEHGHMLM_00021 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEHGHMLM_00022 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
KEHGHMLM_00023 3.53e-168 yteA - - T - - - COG1734 DnaK suppressor protein
KEHGHMLM_00024 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KEHGHMLM_00025 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KEHGHMLM_00026 1.1e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KEHGHMLM_00027 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KEHGHMLM_00028 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KEHGHMLM_00029 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KEHGHMLM_00030 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KEHGHMLM_00031 5.03e-178 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KEHGHMLM_00032 1.5e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KEHGHMLM_00033 3.76e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KEHGHMLM_00034 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
KEHGHMLM_00035 2.83e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KEHGHMLM_00036 7.51e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KEHGHMLM_00037 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KEHGHMLM_00038 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KEHGHMLM_00039 3.41e-112 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KEHGHMLM_00040 1.95e-94 ytkA - - S - - - YtkA-like
KEHGHMLM_00042 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KEHGHMLM_00043 1.59e-81 ytkC - - S - - - Bacteriophage holin family
KEHGHMLM_00044 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KEHGHMLM_00045 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KEHGHMLM_00046 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KEHGHMLM_00047 1.26e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KEHGHMLM_00048 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KEHGHMLM_00049 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
KEHGHMLM_00050 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KEHGHMLM_00051 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KEHGHMLM_00052 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KEHGHMLM_00053 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_00054 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KEHGHMLM_00055 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
KEHGHMLM_00056 2.29e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
KEHGHMLM_00057 1.59e-135 ytqB - - J - - - Putative rRNA methylase
KEHGHMLM_00058 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
KEHGHMLM_00059 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
KEHGHMLM_00061 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
KEHGHMLM_00062 1.4e-205 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_00063 5.22e-187 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KEHGHMLM_00064 1.63e-163 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KEHGHMLM_00065 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_00066 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KEHGHMLM_00067 2.07e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_00068 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
KEHGHMLM_00069 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_00070 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
KEHGHMLM_00071 5.75e-78 yttA - - S - - - Pfam Transposase IS66
KEHGHMLM_00072 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
KEHGHMLM_00073 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KEHGHMLM_00074 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
KEHGHMLM_00075 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KEHGHMLM_00076 1.22e-68 ytwF - - P - - - Sulfurtransferase
KEHGHMLM_00077 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KEHGHMLM_00078 1.48e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KEHGHMLM_00079 4.75e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KEHGHMLM_00080 2.58e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KEHGHMLM_00081 2.17e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_00082 1.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
KEHGHMLM_00083 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KEHGHMLM_00084 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KEHGHMLM_00085 6.91e-280 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KEHGHMLM_00086 9.36e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KEHGHMLM_00087 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KEHGHMLM_00088 4.38e-286 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KEHGHMLM_00089 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
KEHGHMLM_00090 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KEHGHMLM_00091 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KEHGHMLM_00092 0.0 ytdP - - K - - - Transcriptional regulator
KEHGHMLM_00093 6.24e-219 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
KEHGHMLM_00094 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KEHGHMLM_00095 4.78e-94 yteS - - G - - - transport
KEHGHMLM_00096 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
KEHGHMLM_00097 1.55e-149 yteU - - S - - - Integral membrane protein
KEHGHMLM_00098 2.14e-36 yteV - - S - - - Sporulation protein Cse60
KEHGHMLM_00099 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
KEHGHMLM_00100 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
KEHGHMLM_00101 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEHGHMLM_00102 4.3e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KEHGHMLM_00103 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
KEHGHMLM_00104 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KEHGHMLM_00105 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
KEHGHMLM_00106 2.35e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
KEHGHMLM_00107 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
KEHGHMLM_00108 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KEHGHMLM_00109 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KEHGHMLM_00110 4.04e-211 ytlQ - - - - - - -
KEHGHMLM_00111 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KEHGHMLM_00112 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KEHGHMLM_00113 3.02e-192 ytmP - - M - - - Phosphotransferase
KEHGHMLM_00114 9.51e-61 ytzH - - S - - - YtzH-like protein
KEHGHMLM_00115 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KEHGHMLM_00116 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KEHGHMLM_00117 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KEHGHMLM_00118 6.75e-67 ytzB - - S - - - small secreted protein
KEHGHMLM_00119 1.06e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KEHGHMLM_00120 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
KEHGHMLM_00121 3.17e-75 ytpP - - CO - - - Thioredoxin
KEHGHMLM_00122 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
KEHGHMLM_00123 1.2e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEHGHMLM_00124 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KEHGHMLM_00125 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KEHGHMLM_00126 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KEHGHMLM_00127 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
KEHGHMLM_00128 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
KEHGHMLM_00129 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KEHGHMLM_00130 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KEHGHMLM_00131 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KEHGHMLM_00132 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KEHGHMLM_00133 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
KEHGHMLM_00134 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KEHGHMLM_00135 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KEHGHMLM_00136 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KEHGHMLM_00137 1.52e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEHGHMLM_00139 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KEHGHMLM_00140 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
KEHGHMLM_00141 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KEHGHMLM_00142 2.94e-142 yttP - - K - - - Transcriptional regulator
KEHGHMLM_00143 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KEHGHMLM_00144 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KEHGHMLM_00145 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KEHGHMLM_00146 3.34e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KEHGHMLM_00147 2.97e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KEHGHMLM_00148 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
KEHGHMLM_00149 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KEHGHMLM_00150 0.0 ytcJ - - S - - - amidohydrolase
KEHGHMLM_00151 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEHGHMLM_00152 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
KEHGHMLM_00153 2.36e-111 yteJ - - S - - - RDD family
KEHGHMLM_00154 2.05e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
KEHGHMLM_00155 8.51e-96 ytfJ - - S - - - Sporulation protein YtfJ
KEHGHMLM_00156 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KEHGHMLM_00157 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KEHGHMLM_00158 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KEHGHMLM_00159 4.71e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KEHGHMLM_00160 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KEHGHMLM_00161 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KEHGHMLM_00163 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_00164 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
KEHGHMLM_00165 6.8e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
KEHGHMLM_00166 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KEHGHMLM_00167 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KEHGHMLM_00168 1.57e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KEHGHMLM_00169 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_00170 6.48e-153 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_00171 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KEHGHMLM_00172 1.19e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEHGHMLM_00173 1.2e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
KEHGHMLM_00174 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEHGHMLM_00175 2.31e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
KEHGHMLM_00176 4.52e-301 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KEHGHMLM_00177 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
KEHGHMLM_00178 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
KEHGHMLM_00179 2.15e-63 ytpI - - S - - - YtpI-like protein
KEHGHMLM_00180 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
KEHGHMLM_00181 1.15e-39 - - - - - - - -
KEHGHMLM_00182 5.12e-112 ytrI - - - - - - -
KEHGHMLM_00183 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
KEHGHMLM_00184 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KEHGHMLM_00185 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
KEHGHMLM_00186 8.83e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KEHGHMLM_00187 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KEHGHMLM_00188 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KEHGHMLM_00189 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KEHGHMLM_00190 3.85e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
KEHGHMLM_00191 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
KEHGHMLM_00192 1.56e-93 ytwI - - S - - - membrane
KEHGHMLM_00193 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KEHGHMLM_00194 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
KEHGHMLM_00195 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
KEHGHMLM_00196 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_00197 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
KEHGHMLM_00198 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KEHGHMLM_00199 4.05e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KEHGHMLM_00200 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
KEHGHMLM_00201 3.84e-124 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KEHGHMLM_00202 4.54e-205 ytbE - - S - - - reductase
KEHGHMLM_00203 4.57e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
KEHGHMLM_00204 9.85e-88 ytcD - - K - - - Transcriptional regulator
KEHGHMLM_00205 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEHGHMLM_00206 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KEHGHMLM_00207 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KEHGHMLM_00208 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
KEHGHMLM_00209 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KEHGHMLM_00210 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
KEHGHMLM_00211 3.32e-203 ytxC - - S - - - YtxC-like family
KEHGHMLM_00213 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEHGHMLM_00214 1.4e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
KEHGHMLM_00215 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_00216 6.84e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KEHGHMLM_00217 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KEHGHMLM_00218 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KEHGHMLM_00220 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KEHGHMLM_00221 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KEHGHMLM_00222 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KEHGHMLM_00223 1.27e-59 ysdA - - S - - - Membrane
KEHGHMLM_00224 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
KEHGHMLM_00225 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
KEHGHMLM_00226 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KEHGHMLM_00227 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KEHGHMLM_00228 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
KEHGHMLM_00229 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KEHGHMLM_00230 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
KEHGHMLM_00231 1.02e-279 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KEHGHMLM_00232 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KEHGHMLM_00233 5.56e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
KEHGHMLM_00234 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
KEHGHMLM_00235 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
KEHGHMLM_00236 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
KEHGHMLM_00237 1.26e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
KEHGHMLM_00238 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
KEHGHMLM_00239 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
KEHGHMLM_00240 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
KEHGHMLM_00241 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
KEHGHMLM_00242 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEHGHMLM_00243 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KEHGHMLM_00244 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEHGHMLM_00245 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEHGHMLM_00246 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KEHGHMLM_00247 1.55e-111 yshB - - S - - - membrane protein, required for colicin V production
KEHGHMLM_00248 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
KEHGHMLM_00249 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KEHGHMLM_00250 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
KEHGHMLM_00251 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KEHGHMLM_00252 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_00253 4.25e-174 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
KEHGHMLM_00254 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
KEHGHMLM_00255 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
KEHGHMLM_00257 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
KEHGHMLM_00258 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KEHGHMLM_00259 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KEHGHMLM_00260 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KEHGHMLM_00261 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
KEHGHMLM_00262 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
KEHGHMLM_00263 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KEHGHMLM_00264 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
KEHGHMLM_00265 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
KEHGHMLM_00266 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_00267 3.23e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_00268 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KEHGHMLM_00269 3.81e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
KEHGHMLM_00270 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KEHGHMLM_00271 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KEHGHMLM_00272 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KEHGHMLM_00274 7.9e-180 ysnF - - S - - - protein conserved in bacteria
KEHGHMLM_00275 3.93e-177 - - - N - - - domain, Protein
KEHGHMLM_00276 2.52e-102 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
KEHGHMLM_00278 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KEHGHMLM_00279 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KEHGHMLM_00280 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KEHGHMLM_00281 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KEHGHMLM_00282 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KEHGHMLM_00283 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEHGHMLM_00284 7.31e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEHGHMLM_00285 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
KEHGHMLM_00286 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KEHGHMLM_00287 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KEHGHMLM_00288 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
KEHGHMLM_00289 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KEHGHMLM_00290 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KEHGHMLM_00291 8.23e-117 ysxD - - - - - - -
KEHGHMLM_00292 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KEHGHMLM_00293 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
KEHGHMLM_00294 2.19e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KEHGHMLM_00295 6.12e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KEHGHMLM_00296 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
KEHGHMLM_00297 7.12e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KEHGHMLM_00298 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
KEHGHMLM_00299 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KEHGHMLM_00300 1.53e-35 - - - - - - - -
KEHGHMLM_00301 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KEHGHMLM_00302 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KEHGHMLM_00303 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KEHGHMLM_00304 6.07e-211 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
KEHGHMLM_00305 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
KEHGHMLM_00306 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KEHGHMLM_00307 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
KEHGHMLM_00308 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KEHGHMLM_00309 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
KEHGHMLM_00310 1.75e-157 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KEHGHMLM_00311 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KEHGHMLM_00312 1.5e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KEHGHMLM_00313 1.25e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
KEHGHMLM_00314 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KEHGHMLM_00315 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
KEHGHMLM_00316 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KEHGHMLM_00317 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
KEHGHMLM_00318 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KEHGHMLM_00319 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
KEHGHMLM_00320 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KEHGHMLM_00321 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KEHGHMLM_00322 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KEHGHMLM_00323 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KEHGHMLM_00324 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
KEHGHMLM_00325 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KEHGHMLM_00326 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
KEHGHMLM_00327 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEHGHMLM_00328 8.63e-165 yebC - - K - - - transcriptional regulatory protein
KEHGHMLM_00329 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
KEHGHMLM_00331 7.31e-67 - - - S - - - Family of unknown function (DUF5412)
KEHGHMLM_00333 2.32e-152 yrzF - - T - - - serine threonine protein kinase
KEHGHMLM_00334 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
KEHGHMLM_00335 0.0 csbX - - EGP - - - the major facilitator superfamily
KEHGHMLM_00336 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
KEHGHMLM_00337 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KEHGHMLM_00338 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KEHGHMLM_00339 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
KEHGHMLM_00340 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KEHGHMLM_00341 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KEHGHMLM_00342 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
KEHGHMLM_00343 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
KEHGHMLM_00344 6.34e-147 yrbG - - S - - - membrane
KEHGHMLM_00345 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEHGHMLM_00346 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
KEHGHMLM_00347 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KEHGHMLM_00348 1.87e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KEHGHMLM_00349 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
KEHGHMLM_00350 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KEHGHMLM_00351 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KEHGHMLM_00352 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KEHGHMLM_00353 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEHGHMLM_00354 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
KEHGHMLM_00356 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KEHGHMLM_00357 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KEHGHMLM_00358 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KEHGHMLM_00359 2.33e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KEHGHMLM_00360 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_00361 2.66e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KEHGHMLM_00362 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KEHGHMLM_00363 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
KEHGHMLM_00364 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KEHGHMLM_00365 3.54e-108 yrrD - - S - - - protein conserved in bacteria
KEHGHMLM_00366 8.4e-42 yrzR - - - - - - -
KEHGHMLM_00367 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
KEHGHMLM_00368 3.77e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KEHGHMLM_00369 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KEHGHMLM_00370 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KEHGHMLM_00371 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KEHGHMLM_00372 3.07e-242 yrrI - - S - - - AI-2E family transporter
KEHGHMLM_00373 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KEHGHMLM_00374 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
KEHGHMLM_00375 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KEHGHMLM_00376 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
KEHGHMLM_00377 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KEHGHMLM_00378 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
KEHGHMLM_00379 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KEHGHMLM_00380 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
KEHGHMLM_00381 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KEHGHMLM_00382 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KEHGHMLM_00383 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
KEHGHMLM_00384 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
KEHGHMLM_00385 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
KEHGHMLM_00386 8.44e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
KEHGHMLM_00387 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KEHGHMLM_00388 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
KEHGHMLM_00389 5.77e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KEHGHMLM_00390 6.93e-49 yrhC - - S - - - YrhC-like protein
KEHGHMLM_00391 4.36e-104 ydcL - - L - - - Belongs to the 'phage' integrase family
KEHGHMLM_00392 6.1e-53 - - - E - - - Pfam:DUF955
KEHGHMLM_00393 1.22e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
KEHGHMLM_00394 2.06e-10 - - - - - - - -
KEHGHMLM_00395 4.75e-47 - - - - - - - -
KEHGHMLM_00397 9.11e-84 - - - S - - - Bacterial protein of unknown function (DUF961)
KEHGHMLM_00398 2.71e-96 - - - - - - - -
KEHGHMLM_00399 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
KEHGHMLM_00400 7.94e-249 nicK - - L ko:K07467 - ko00000 Replication initiation factor
KEHGHMLM_00401 2.37e-86 - - - M - - - Acetyltransferase (GNAT) domain
KEHGHMLM_00404 2.05e-62 yddA - - - - - - -
KEHGHMLM_00405 3.54e-221 yddB - - S - - - Conjugative transposon protein TcpC
KEHGHMLM_00406 3.41e-54 yddC - - - - - - -
KEHGHMLM_00407 4.52e-123 yddD - - S - - - TcpE family
KEHGHMLM_00408 0.0 yddE - - S - - - AAA-like domain
KEHGHMLM_00409 4.67e-73 - - - S - - - Domain of unknown function (DUF1874)
KEHGHMLM_00410 0.0 yddG - - S - - - maturation of SSU-rRNA
KEHGHMLM_00411 2.52e-238 yddH - - M - - - Lysozyme-like
KEHGHMLM_00412 4.36e-109 yddI - - - - - - -
KEHGHMLM_00413 1.38e-51 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
KEHGHMLM_00414 6.02e-52 - - - S - - - SIR2-like domain
KEHGHMLM_00416 7.93e-85 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KEHGHMLM_00418 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
KEHGHMLM_00419 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
KEHGHMLM_00420 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
KEHGHMLM_00421 5.62e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
KEHGHMLM_00423 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
KEHGHMLM_00424 7.13e-123 yrhH - - Q - - - methyltransferase
KEHGHMLM_00425 3.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
KEHGHMLM_00426 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KEHGHMLM_00427 2.67e-62 yrhK - - S - - - YrhK-like protein
KEHGHMLM_00428 0.0 oatA - - I - - - Acyltransferase family
KEHGHMLM_00429 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
KEHGHMLM_00430 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_00431 1.14e-191 yrhO - - K - - - Archaeal transcriptional regulator TrmB
KEHGHMLM_00432 5.63e-137 yrhP - - E - - - LysE type translocator
KEHGHMLM_00433 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_00434 0.0 levR - - K - - - PTS system fructose IIA component
KEHGHMLM_00435 2.18e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KEHGHMLM_00436 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
KEHGHMLM_00437 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KEHGHMLM_00438 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KEHGHMLM_00439 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KEHGHMLM_00440 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KEHGHMLM_00441 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
KEHGHMLM_00442 2.61e-14 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
KEHGHMLM_00443 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KEHGHMLM_00444 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
KEHGHMLM_00445 6.11e-36 yraE - - - ko:K06440 - ko00000 -
KEHGHMLM_00446 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KEHGHMLM_00447 9.61e-84 yraF - - M - - - Spore coat protein
KEHGHMLM_00448 1.2e-49 yraG - - - ko:K06440 - ko00000 -
KEHGHMLM_00449 5.24e-84 - - - E - - - Glyoxalase-like domain
KEHGHMLM_00450 5.9e-81 - - - T - - - sh3 domain protein
KEHGHMLM_00451 2.69e-79 - - - T - - - sh3 domain protein
KEHGHMLM_00452 1.76e-193 - - - S - - - Alpha beta hydrolase
KEHGHMLM_00453 2.51e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_00454 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KEHGHMLM_00455 2.71e-259 yraM - - S - - - PrpF protein
KEHGHMLM_00456 7e-209 yraN - - K - - - Transcriptional regulator
KEHGHMLM_00457 1.02e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KEHGHMLM_00458 3.26e-139 yrpG - - C - - - Aldo/keto reductase family
KEHGHMLM_00459 3.3e-85 yrpG - - C - - - Aldo/keto reductase family
KEHGHMLM_00460 1.24e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_00461 2.55e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KEHGHMLM_00463 2.29e-160 yrpD - - S - - - Domain of unknown function, YrpD
KEHGHMLM_00464 2.01e-101 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KEHGHMLM_00465 2.1e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KEHGHMLM_00466 2.98e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
KEHGHMLM_00467 2.75e-116 yrdA - - S - - - DinB family
KEHGHMLM_00468 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
KEHGHMLM_00469 2.11e-130 yrdC - - Q - - - Isochorismatase family
KEHGHMLM_00470 1.44e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KEHGHMLM_00471 2.73e-33 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
KEHGHMLM_00472 8.34e-104 bkdR - - K - - - helix_turn_helix ASNC type
KEHGHMLM_00473 9.34e-176 azlC - - E - - - AzlC protein
KEHGHMLM_00474 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
KEHGHMLM_00475 5.81e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KEHGHMLM_00476 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
KEHGHMLM_00477 2.05e-86 yodA - - S - - - tautomerase
KEHGHMLM_00478 2.79e-202 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
KEHGHMLM_00479 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
KEHGHMLM_00480 3.3e-202 - - - K - - - Transcriptional regulator
KEHGHMLM_00481 7.28e-218 yrdR - - EG - - - EamA-like transporter family
KEHGHMLM_00482 2.45e-23 - - - S - - - YrzO-like protein
KEHGHMLM_00483 6.45e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KEHGHMLM_00484 8.79e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
KEHGHMLM_00485 1.87e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_00486 5.9e-193 bltR - - K - - - helix_turn_helix, mercury resistance
KEHGHMLM_00487 2.21e-138 yrkC - - G - - - Cupin domain
KEHGHMLM_00488 4.38e-52 yrkD - - S - - - protein conserved in bacteria
KEHGHMLM_00489 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
KEHGHMLM_00490 4.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
KEHGHMLM_00491 4.57e-59 perX - - S - - - DsrE/DsrF-like family
KEHGHMLM_00492 1.98e-261 yrkH - - P - - - Rhodanese Homology Domain
KEHGHMLM_00493 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
KEHGHMLM_00494 5.31e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
KEHGHMLM_00495 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
KEHGHMLM_00496 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
KEHGHMLM_00497 5.41e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
KEHGHMLM_00498 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KEHGHMLM_00499 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
KEHGHMLM_00500 8.54e-305 yrkQ - - T - - - Histidine kinase
KEHGHMLM_00501 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
KEHGHMLM_00502 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_00503 1.58e-122 xkdA - - E - - - IrrE N-terminal-like domain
KEHGHMLM_00504 8.73e-132 yqaC - - F - - - adenylate kinase activity
KEHGHMLM_00506 1.25e-74 - - - K - - - sequence-specific DNA binding
KEHGHMLM_00507 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
KEHGHMLM_00509 1.27e-134 - - - - - - - -
KEHGHMLM_00513 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
KEHGHMLM_00514 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
KEHGHMLM_00515 1.92e-158 yqaL - - L - - - DnaD domain protein
KEHGHMLM_00516 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
KEHGHMLM_00518 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
KEHGHMLM_00519 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
KEHGHMLM_00520 7.56e-214 - - - - - - - -
KEHGHMLM_00521 1.58e-105 yqaQ - - L - - - Transposase
KEHGHMLM_00523 2.02e-158 yqaS - - L - - - DNA packaging
KEHGHMLM_00524 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
KEHGHMLM_00525 0.0 yqbA - - S - - - portal protein
KEHGHMLM_00526 1.73e-217 - - - S - - - Phage Mu protein F like protein
KEHGHMLM_00527 2.13e-149 - - - - - - - -
KEHGHMLM_00528 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
KEHGHMLM_00529 9.21e-216 xkdG - - S - - - Phage capsid family
KEHGHMLM_00530 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
KEHGHMLM_00531 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
KEHGHMLM_00532 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
KEHGHMLM_00533 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KEHGHMLM_00534 3.24e-102 yqbJ - - - - - - -
KEHGHMLM_00535 2.52e-36 - - - - - - - -
KEHGHMLM_00536 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
KEHGHMLM_00537 4.23e-99 xkdM - - S - - - Phage tail tube protein
KEHGHMLM_00539 1.58e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KEHGHMLM_00540 0.0 xkdO - - L - - - Transglycosylase SLT domain
KEHGHMLM_00541 3.12e-154 xkdP - - S - - - Lysin motif
KEHGHMLM_00542 1.81e-225 xkdQ - - G - - - NLP P60 protein
KEHGHMLM_00543 4.54e-48 xkdR - - S - - - Protein of unknown function (DUF2577)
KEHGHMLM_00544 1.75e-86 xkdS - - S - - - Protein of unknown function (DUF2634)
KEHGHMLM_00545 3.86e-238 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KEHGHMLM_00546 9.55e-127 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KEHGHMLM_00547 8.29e-52 - - - - - - - -
KEHGHMLM_00548 1.19e-282 - - - - - - - -
KEHGHMLM_00549 1.01e-73 xkdW - - S - - - XkdW protein
KEHGHMLM_00550 9.34e-33 - - - - - - - -
KEHGHMLM_00551 1.46e-205 xepA - - - - - - -
KEHGHMLM_00552 5.65e-87 - - - S - - - Bacteriophage holin family
KEHGHMLM_00553 8.93e-183 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KEHGHMLM_00555 5.4e-80 - - - - - - - -
KEHGHMLM_00557 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
KEHGHMLM_00558 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
KEHGHMLM_00561 8.68e-120 - - - S - - - Tetratricopeptide repeat
KEHGHMLM_00562 1.7e-187 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
KEHGHMLM_00563 2.17e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
KEHGHMLM_00564 3.34e-91 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_00565 1.18e-231 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
KEHGHMLM_00566 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KEHGHMLM_00567 0.0 - - - L ko:K06400 - ko00000 Recombinase
KEHGHMLM_00568 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_00569 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
KEHGHMLM_00570 9.38e-171 - - - - - - - -
KEHGHMLM_00571 6.26e-216 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
KEHGHMLM_00572 5.41e-134 yqeD - - S - - - SNARE associated Golgi protein
KEHGHMLM_00573 2.2e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KEHGHMLM_00574 9.11e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
KEHGHMLM_00576 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KEHGHMLM_00577 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KEHGHMLM_00578 9.86e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KEHGHMLM_00579 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
KEHGHMLM_00580 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KEHGHMLM_00581 1.13e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KEHGHMLM_00582 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KEHGHMLM_00583 1.39e-178 yqeM - - Q - - - Methyltransferase
KEHGHMLM_00584 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEHGHMLM_00585 7.77e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KEHGHMLM_00586 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KEHGHMLM_00587 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KEHGHMLM_00588 2.36e-22 - - - S - - - YqzM-like protein
KEHGHMLM_00589 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KEHGHMLM_00590 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KEHGHMLM_00591 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KEHGHMLM_00592 3.88e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
KEHGHMLM_00593 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
KEHGHMLM_00594 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KEHGHMLM_00595 1.68e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KEHGHMLM_00596 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KEHGHMLM_00597 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KEHGHMLM_00598 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KEHGHMLM_00599 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KEHGHMLM_00600 4.63e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
KEHGHMLM_00601 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KEHGHMLM_00602 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
KEHGHMLM_00603 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KEHGHMLM_00604 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KEHGHMLM_00605 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
KEHGHMLM_00606 9.29e-291 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
KEHGHMLM_00607 2.06e-190 yqfA - - S - - - UPF0365 protein
KEHGHMLM_00608 1.37e-73 yqfB - - - - - - -
KEHGHMLM_00609 2.07e-60 yqfC - - S - - - sporulation protein YqfC
KEHGHMLM_00610 9.93e-241 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
KEHGHMLM_00611 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
KEHGHMLM_00613 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
KEHGHMLM_00614 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KEHGHMLM_00615 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KEHGHMLM_00616 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KEHGHMLM_00617 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KEHGHMLM_00618 5.29e-27 - - - S - - - YqzL-like protein
KEHGHMLM_00619 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KEHGHMLM_00620 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KEHGHMLM_00621 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KEHGHMLM_00622 3.29e-144 ccpN - - K - - - CBS domain
KEHGHMLM_00623 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KEHGHMLM_00624 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
KEHGHMLM_00625 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KEHGHMLM_00626 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KEHGHMLM_00627 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KEHGHMLM_00628 4.66e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KEHGHMLM_00629 3.77e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KEHGHMLM_00630 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KEHGHMLM_00631 4.89e-58 yqfQ - - S - - - YqfQ-like protein
KEHGHMLM_00632 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KEHGHMLM_00633 1.72e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KEHGHMLM_00634 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
KEHGHMLM_00635 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KEHGHMLM_00636 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
KEHGHMLM_00637 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
KEHGHMLM_00638 2.04e-81 yqfX - - S - - - membrane
KEHGHMLM_00639 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KEHGHMLM_00640 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
KEHGHMLM_00641 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
KEHGHMLM_00642 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
KEHGHMLM_00643 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KEHGHMLM_00644 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
KEHGHMLM_00645 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KEHGHMLM_00646 1.51e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KEHGHMLM_00647 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KEHGHMLM_00648 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KEHGHMLM_00649 2.8e-189 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEHGHMLM_00650 6.37e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEHGHMLM_00651 1.09e-93 yqzC - - S - - - YceG-like family
KEHGHMLM_00652 2.81e-67 yqzD - - - - - - -
KEHGHMLM_00654 3.36e-249 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
KEHGHMLM_00655 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KEHGHMLM_00656 1.05e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KEHGHMLM_00657 3.38e-14 yqgO - - - - - - -
KEHGHMLM_00658 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KEHGHMLM_00659 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
KEHGHMLM_00660 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KEHGHMLM_00661 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KEHGHMLM_00662 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
KEHGHMLM_00663 5.65e-258 yqgU - - - - - - -
KEHGHMLM_00664 7.34e-66 yqgV - - S - - - Thiamine-binding protein
KEHGHMLM_00665 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
KEHGHMLM_00666 7.54e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KEHGHMLM_00667 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
KEHGHMLM_00668 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KEHGHMLM_00670 2.05e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEHGHMLM_00671 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KEHGHMLM_00672 1.51e-233 yqxL - - P - - - Mg2 transporter protein
KEHGHMLM_00673 4.13e-08 yhcV - - S - - - COG0517 FOG CBS domain
KEHGHMLM_00674 5.23e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KEHGHMLM_00675 8.73e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
KEHGHMLM_00676 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KEHGHMLM_00677 4.62e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
KEHGHMLM_00678 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
KEHGHMLM_00679 2.47e-61 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KEHGHMLM_00680 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
KEHGHMLM_00681 3.33e-35 yqzE - - S - - - YqzE-like protein
KEHGHMLM_00682 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
KEHGHMLM_00683 9.75e-157 yqxM - - - ko:K19433 - ko00000 -
KEHGHMLM_00684 3.5e-96 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
KEHGHMLM_00685 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
KEHGHMLM_00686 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
KEHGHMLM_00687 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
KEHGHMLM_00688 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
KEHGHMLM_00689 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KEHGHMLM_00690 3.17e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
KEHGHMLM_00691 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KEHGHMLM_00692 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KEHGHMLM_00693 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
KEHGHMLM_00694 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KEHGHMLM_00695 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KEHGHMLM_00696 5.75e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KEHGHMLM_00697 5.18e-81 yqhP - - - - - - -
KEHGHMLM_00698 8.55e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
KEHGHMLM_00699 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
KEHGHMLM_00700 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KEHGHMLM_00701 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KEHGHMLM_00702 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KEHGHMLM_00703 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
KEHGHMLM_00704 2.02e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
KEHGHMLM_00705 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
KEHGHMLM_00706 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
KEHGHMLM_00707 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
KEHGHMLM_00708 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
KEHGHMLM_00709 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
KEHGHMLM_00710 8.86e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
KEHGHMLM_00711 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
KEHGHMLM_00712 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KEHGHMLM_00713 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KEHGHMLM_00714 1.65e-88 yqhY - - S - - - protein conserved in bacteria
KEHGHMLM_00715 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KEHGHMLM_00716 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KEHGHMLM_00717 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEHGHMLM_00718 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEHGHMLM_00719 2.43e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KEHGHMLM_00720 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KEHGHMLM_00721 1.02e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
KEHGHMLM_00722 1.53e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KEHGHMLM_00723 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KEHGHMLM_00724 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
KEHGHMLM_00725 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KEHGHMLM_00727 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KEHGHMLM_00728 2.74e-36 - - - - - - - -
KEHGHMLM_00729 2.7e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
KEHGHMLM_00730 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KEHGHMLM_00731 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KEHGHMLM_00732 1.45e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
KEHGHMLM_00733 6.02e-269 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
KEHGHMLM_00734 4.75e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KEHGHMLM_00735 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
KEHGHMLM_00736 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KEHGHMLM_00737 1.82e-45 yqzF - - S - - - Protein of unknown function (DUF2627)
KEHGHMLM_00738 0.0 bkdR - - KT - - - Transcriptional regulator
KEHGHMLM_00739 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
KEHGHMLM_00740 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KEHGHMLM_00741 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
KEHGHMLM_00742 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEHGHMLM_00743 2.24e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEHGHMLM_00744 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEHGHMLM_00745 4.4e-287 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEHGHMLM_00746 4.31e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
KEHGHMLM_00747 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_00748 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KEHGHMLM_00749 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
KEHGHMLM_00750 2.89e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KEHGHMLM_00751 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KEHGHMLM_00752 1.74e-164 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KEHGHMLM_00753 1.88e-225 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
KEHGHMLM_00754 2.32e-126 yqjB - - S - - - protein conserved in bacteria
KEHGHMLM_00756 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
KEHGHMLM_00757 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEHGHMLM_00758 1.76e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
KEHGHMLM_00759 2.82e-180 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
KEHGHMLM_00760 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEHGHMLM_00761 1.77e-32 yqzJ - - - - - - -
KEHGHMLM_00762 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEHGHMLM_00763 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEHGHMLM_00764 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KEHGHMLM_00765 3.12e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KEHGHMLM_00766 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KEHGHMLM_00767 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEHGHMLM_00768 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KEHGHMLM_00769 0.0 rocB - - E - - - arginine degradation protein
KEHGHMLM_00770 2.67e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEHGHMLM_00771 2.69e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KEHGHMLM_00772 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_00773 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
KEHGHMLM_00774 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KEHGHMLM_00775 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_00777 2.28e-286 yqjV - - G - - - Major Facilitator Superfamily
KEHGHMLM_00779 1.99e-302 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEHGHMLM_00780 3.23e-66 yqiX - - S - - - YolD-like protein
KEHGHMLM_00781 1.29e-111 yqjY - - K ko:K06977 - ko00000 acetyltransferase
KEHGHMLM_00782 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
KEHGHMLM_00783 2.28e-248 yqkA - - K - - - GrpB protein
KEHGHMLM_00784 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
KEHGHMLM_00785 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
KEHGHMLM_00786 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KEHGHMLM_00787 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
KEHGHMLM_00788 5.13e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
KEHGHMLM_00789 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
KEHGHMLM_00790 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KEHGHMLM_00791 1.98e-278 yqxK - - L - - - DNA helicase
KEHGHMLM_00792 1.29e-76 ansR - - K - - - Transcriptional regulator
KEHGHMLM_00793 3.58e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
KEHGHMLM_00794 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
KEHGHMLM_00795 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KEHGHMLM_00796 5.62e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KEHGHMLM_00797 7.27e-42 yqkK - - - - - - -
KEHGHMLM_00798 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KEHGHMLM_00799 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KEHGHMLM_00800 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
KEHGHMLM_00801 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
KEHGHMLM_00802 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KEHGHMLM_00803 8.04e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KEHGHMLM_00804 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KEHGHMLM_00805 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
KEHGHMLM_00806 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KEHGHMLM_00807 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_00808 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
KEHGHMLM_00809 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
KEHGHMLM_00810 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
KEHGHMLM_00811 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
KEHGHMLM_00812 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
KEHGHMLM_00813 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
KEHGHMLM_00814 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
KEHGHMLM_00815 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KEHGHMLM_00816 2.67e-193 ypuA - - S - - - Secreted protein
KEHGHMLM_00817 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KEHGHMLM_00820 5.49e-17 - - - S - - - SNARE associated Golgi protein
KEHGHMLM_00821 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
KEHGHMLM_00822 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KEHGHMLM_00823 5.98e-72 ypuD - - - - - - -
KEHGHMLM_00824 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KEHGHMLM_00825 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KEHGHMLM_00826 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KEHGHMLM_00827 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KEHGHMLM_00828 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_00829 5.92e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
KEHGHMLM_00830 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KEHGHMLM_00831 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KEHGHMLM_00832 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
KEHGHMLM_00833 2.28e-270 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KEHGHMLM_00834 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
KEHGHMLM_00835 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
KEHGHMLM_00836 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KEHGHMLM_00837 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KEHGHMLM_00838 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
KEHGHMLM_00839 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KEHGHMLM_00840 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_00841 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_00842 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_00843 1.49e-254 rsiX - - - - - - -
KEHGHMLM_00844 1.67e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KEHGHMLM_00845 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEHGHMLM_00846 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KEHGHMLM_00847 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
KEHGHMLM_00848 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
KEHGHMLM_00849 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KEHGHMLM_00850 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
KEHGHMLM_00851 9.72e-146 ypbE - - M - - - Lysin motif
KEHGHMLM_00852 8.23e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
KEHGHMLM_00853 1.97e-184 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KEHGHMLM_00854 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KEHGHMLM_00855 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KEHGHMLM_00856 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
KEHGHMLM_00857 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
KEHGHMLM_00858 5.69e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
KEHGHMLM_00859 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
KEHGHMLM_00860 2.2e-142 ypfA - - M - - - Flagellar protein YcgR
KEHGHMLM_00861 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
KEHGHMLM_00862 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KEHGHMLM_00863 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KEHGHMLM_00864 3.28e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KEHGHMLM_00865 1.13e-11 - - - S - - - YpzI-like protein
KEHGHMLM_00866 3.18e-133 yphA - - - - - - -
KEHGHMLM_00867 1.77e-206 yphB - - S ko:K05739 - ko00000 YIEGIA protein
KEHGHMLM_00868 2.06e-38 ypzH - - - - - - -
KEHGHMLM_00869 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KEHGHMLM_00870 9.24e-228 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KEHGHMLM_00871 3.51e-27 yphE - - S - - - Protein of unknown function (DUF2768)
KEHGHMLM_00872 9.07e-178 yphF - - - - - - -
KEHGHMLM_00873 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KEHGHMLM_00874 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KEHGHMLM_00875 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KEHGHMLM_00876 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KEHGHMLM_00877 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KEHGHMLM_00878 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KEHGHMLM_00879 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KEHGHMLM_00880 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KEHGHMLM_00881 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
KEHGHMLM_00882 2.91e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KEHGHMLM_00883 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KEHGHMLM_00884 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KEHGHMLM_00885 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEHGHMLM_00886 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KEHGHMLM_00887 1.2e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KEHGHMLM_00888 2.71e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
KEHGHMLM_00889 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KEHGHMLM_00890 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KEHGHMLM_00891 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KEHGHMLM_00892 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KEHGHMLM_00893 1.35e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KEHGHMLM_00894 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
KEHGHMLM_00895 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
KEHGHMLM_00896 3.75e-98 ypiF - - S - - - Protein of unknown function (DUF2487)
KEHGHMLM_00897 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
KEHGHMLM_00898 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
KEHGHMLM_00899 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
KEHGHMLM_00900 2.82e-126 ypjA - - S - - - membrane
KEHGHMLM_00901 2.79e-182 ypjB - - S - - - sporulation protein
KEHGHMLM_00902 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KEHGHMLM_00903 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
KEHGHMLM_00904 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KEHGHMLM_00905 4.19e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
KEHGHMLM_00906 1.56e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
KEHGHMLM_00907 4.94e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
KEHGHMLM_00908 3.04e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KEHGHMLM_00909 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KEHGHMLM_00910 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KEHGHMLM_00911 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KEHGHMLM_00912 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KEHGHMLM_00913 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KEHGHMLM_00914 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
KEHGHMLM_00915 2.66e-102 ypmB - - S - - - protein conserved in bacteria
KEHGHMLM_00916 1.25e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KEHGHMLM_00917 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
KEHGHMLM_00918 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
KEHGHMLM_00919 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KEHGHMLM_00920 1.43e-121 ypoC - - - - - - -
KEHGHMLM_00921 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KEHGHMLM_00922 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KEHGHMLM_00923 6.19e-239 yppC - - S - - - Protein of unknown function (DUF2515)
KEHGHMLM_00926 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
KEHGHMLM_00927 9.21e-11 - - - S - - - YppF-like protein
KEHGHMLM_00928 8.72e-68 yppG - - S - - - YppG-like protein
KEHGHMLM_00929 1.76e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KEHGHMLM_00930 1.75e-108 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
KEHGHMLM_00931 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KEHGHMLM_00932 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
KEHGHMLM_00933 1.19e-128 ypsA - - S - - - Belongs to the UPF0398 family
KEHGHMLM_00934 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KEHGHMLM_00935 1.11e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KEHGHMLM_00937 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
KEHGHMLM_00938 1.68e-178 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_00939 1.03e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KEHGHMLM_00940 2.14e-235 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
KEHGHMLM_00941 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
KEHGHMLM_00942 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
KEHGHMLM_00943 6.77e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KEHGHMLM_00944 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KEHGHMLM_00945 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KEHGHMLM_00946 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
KEHGHMLM_00947 2.16e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
KEHGHMLM_00948 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
KEHGHMLM_00949 0.0 ypbR - - S - - - Dynamin family
KEHGHMLM_00950 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
KEHGHMLM_00951 1.08e-11 - - - - - - - -
KEHGHMLM_00952 2.26e-213 ypcP - - L - - - 5'3' exonuclease
KEHGHMLM_00953 5.23e-05 - - - - ko:K06429 - ko00000 -
KEHGHMLM_00954 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
KEHGHMLM_00955 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KEHGHMLM_00956 9.17e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
KEHGHMLM_00957 7.99e-41 ypeQ - - S - - - Zinc-finger
KEHGHMLM_00958 6.1e-40 - - - S - - - Protein of unknown function (DUF2564)
KEHGHMLM_00959 1.17e-22 degR - - - - - - -
KEHGHMLM_00960 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KEHGHMLM_00961 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KEHGHMLM_00963 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KEHGHMLM_00964 2.21e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KEHGHMLM_00965 1.34e-137 yagB - - S ko:K06950 - ko00000 phosphohydrolase
KEHGHMLM_00966 3.46e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
KEHGHMLM_00967 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KEHGHMLM_00968 1.96e-98 yphP - - S - - - Belongs to the UPF0403 family
KEHGHMLM_00969 1.19e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
KEHGHMLM_00970 1.16e-146 ypjP - - S - - - YpjP-like protein
KEHGHMLM_00971 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KEHGHMLM_00972 5.74e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KEHGHMLM_00973 9.96e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KEHGHMLM_00974 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KEHGHMLM_00975 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KEHGHMLM_00976 1.4e-236 yplP - - K - - - Transcriptional regulator
KEHGHMLM_00977 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KEHGHMLM_00978 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
KEHGHMLM_00979 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KEHGHMLM_00980 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
KEHGHMLM_00981 6.8e-129 ypmS - - S - - - protein conserved in bacteria
KEHGHMLM_00982 2.13e-40 ypmT - - S - - - Uncharacterized ympT
KEHGHMLM_00983 9.99e-290 mepA - - V - - - MATE efflux family protein
KEHGHMLM_00984 4.14e-94 ypoP - - K - - - transcriptional
KEHGHMLM_00985 1.4e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KEHGHMLM_00986 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KEHGHMLM_00987 4.75e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KEHGHMLM_00988 2.31e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
KEHGHMLM_00989 5.72e-238 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
KEHGHMLM_00990 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
KEHGHMLM_00991 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
KEHGHMLM_00992 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
KEHGHMLM_00993 9.78e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
KEHGHMLM_00995 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEHGHMLM_00996 3.41e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KEHGHMLM_00997 7.76e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KEHGHMLM_00998 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
KEHGHMLM_00999 2.61e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
KEHGHMLM_01000 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
KEHGHMLM_01001 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
KEHGHMLM_01002 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
KEHGHMLM_01003 1.29e-159 yodN - - - - - - -
KEHGHMLM_01005 5.18e-34 yozD - - S - - - YozD-like protein
KEHGHMLM_01006 5.48e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KEHGHMLM_01007 1.17e-71 yodL - - S - - - YodL-like
KEHGHMLM_01008 2.08e-12 - - - - - - - -
KEHGHMLM_01009 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KEHGHMLM_01010 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KEHGHMLM_01011 2.93e-42 yodI - - - - - - -
KEHGHMLM_01012 3.69e-167 yodH - - Q - - - Methyltransferase
KEHGHMLM_01013 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KEHGHMLM_01014 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEHGHMLM_01015 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
KEHGHMLM_01016 2.28e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KEHGHMLM_01017 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
KEHGHMLM_01018 1.11e-139 yodC - - C - - - nitroreductase
KEHGHMLM_01019 2.63e-73 yodB - - K - - - transcriptional
KEHGHMLM_01020 5.64e-84 iolK - - S - - - tautomerase
KEHGHMLM_01021 9.24e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KEHGHMLM_01022 1.95e-14 - - - - - - - -
KEHGHMLM_01023 5.82e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
KEHGHMLM_01024 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
KEHGHMLM_01025 1.85e-58 - - - - - - - -
KEHGHMLM_01026 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
KEHGHMLM_01027 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
KEHGHMLM_01028 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEHGHMLM_01029 6.88e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KEHGHMLM_01031 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEHGHMLM_01032 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
KEHGHMLM_01033 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KEHGHMLM_01034 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KEHGHMLM_01035 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
KEHGHMLM_01036 0.0 yojO - - P - - - Von Willebrand factor
KEHGHMLM_01037 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KEHGHMLM_01038 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KEHGHMLM_01039 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
KEHGHMLM_01040 6.18e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KEHGHMLM_01041 1.36e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
KEHGHMLM_01042 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
KEHGHMLM_01043 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KEHGHMLM_01044 1.91e-42 yozC - - - - - - -
KEHGHMLM_01045 2.17e-74 yozO - - S - - - Bacterial PH domain
KEHGHMLM_01046 1.83e-49 yocN - - - - - - -
KEHGHMLM_01047 2.94e-55 yozN - - - - - - -
KEHGHMLM_01048 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KEHGHMLM_01049 7.29e-46 - - - - - - - -
KEHGHMLM_01050 3.02e-70 yocL - - - - - - -
KEHGHMLM_01051 1.42e-107 yocK - - T - - - general stress protein
KEHGHMLM_01052 1.4e-145 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KEHGHMLM_01053 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
KEHGHMLM_01054 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
KEHGHMLM_01055 1.92e-134 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_01056 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_01057 2.81e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KEHGHMLM_01058 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
KEHGHMLM_01059 1.08e-121 yocC - - - - - - -
KEHGHMLM_01060 2.61e-18 - - - - - - - -
KEHGHMLM_01061 9.79e-130 - - - - - - - -
KEHGHMLM_01062 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
KEHGHMLM_01063 2.89e-151 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEHGHMLM_01064 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
KEHGHMLM_01065 3.01e-120 yobW - - - - - - -
KEHGHMLM_01066 2.3e-226 yobV - - K - - - WYL domain
KEHGHMLM_01067 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
KEHGHMLM_01068 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KEHGHMLM_01069 2e-123 yobS - - K - - - Transcriptional regulator
KEHGHMLM_01070 4.16e-180 - - - J - - - FR47-like protein
KEHGHMLM_01071 6.36e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
KEHGHMLM_01072 7.4e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
KEHGHMLM_01073 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
KEHGHMLM_01074 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
KEHGHMLM_01075 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KEHGHMLM_01076 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
KEHGHMLM_01077 1.09e-134 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KEHGHMLM_01078 0.0 aga 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
KEHGHMLM_01079 1.33e-141 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_01080 5.77e-58 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KEHGHMLM_01081 5.09e-53 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KEHGHMLM_01083 1.23e-272 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
KEHGHMLM_01084 3.14e-167 - - - K - - - Bacterial regulatory proteins, lacI family
KEHGHMLM_01085 1.04e-219 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KEHGHMLM_01086 2.71e-29 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEHGHMLM_01087 1.48e-30 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
KEHGHMLM_01088 9.27e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KEHGHMLM_01089 1.08e-73 - - - K - - - Helix-turn-helix
KEHGHMLM_01090 6.27e-51 - - - S - - - TM2 domain
KEHGHMLM_01091 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
KEHGHMLM_01092 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
KEHGHMLM_01095 1.47e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
KEHGHMLM_01096 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
KEHGHMLM_01097 1.33e-100 yoaW - - - - - - -
KEHGHMLM_01098 4.32e-200 yoaV - - EG - - - EamA-like transporter family
KEHGHMLM_01099 7.78e-202 yoaU - - K - - - LysR substrate binding domain
KEHGHMLM_01100 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
KEHGHMLM_01101 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_01102 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
KEHGHMLM_01103 1.04e-217 yoaR - - V - - - vancomycin resistance protein
KEHGHMLM_01104 1.53e-112 - - - - - - - -
KEHGHMLM_01106 1.49e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
KEHGHMLM_01107 3.71e-185 yoaP - - K - - - YoaP-like
KEHGHMLM_01109 1.21e-290 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KEHGHMLM_01112 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
KEHGHMLM_01113 2.38e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
KEHGHMLM_01114 1.79e-145 yoaK - - S - - - Membrane
KEHGHMLM_01115 5.06e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
KEHGHMLM_01116 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
KEHGHMLM_01117 3.58e-314 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
KEHGHMLM_01118 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
KEHGHMLM_01119 1.2e-18 - - - - - - - -
KEHGHMLM_01121 7.24e-45 yoaF - - - - - - -
KEHGHMLM_01122 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEHGHMLM_01123 1.37e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEHGHMLM_01124 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
KEHGHMLM_01125 1.51e-298 yoaB - - EGP - - - the major facilitator superfamily
KEHGHMLM_01126 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
KEHGHMLM_01127 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
KEHGHMLM_01128 1.14e-113 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEHGHMLM_01129 5.51e-168 yoxB - - - - - - -
KEHGHMLM_01130 9.05e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
KEHGHMLM_01131 6.25e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_01132 5.59e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KEHGHMLM_01133 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEHGHMLM_01134 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEHGHMLM_01135 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_01136 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
KEHGHMLM_01137 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KEHGHMLM_01138 1.2e-236 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KEHGHMLM_01139 9.8e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_01140 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KEHGHMLM_01141 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
KEHGHMLM_01142 1.14e-124 - - - L - - - Integrase
KEHGHMLM_01144 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
KEHGHMLM_01145 9.8e-313 yoeA - - V - - - MATE efflux family protein
KEHGHMLM_01146 2.73e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KEHGHMLM_01147 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KEHGHMLM_01148 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_01149 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_01150 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_01151 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_01152 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
KEHGHMLM_01153 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
KEHGHMLM_01154 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
KEHGHMLM_01155 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KEHGHMLM_01156 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KEHGHMLM_01157 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KEHGHMLM_01158 9.05e-313 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
KEHGHMLM_01159 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
KEHGHMLM_01160 5.77e-213 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
KEHGHMLM_01161 8.57e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
KEHGHMLM_01162 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KEHGHMLM_01163 5.21e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
KEHGHMLM_01164 2.01e-134 yngC - - S - - - membrane-associated protein
KEHGHMLM_01165 6.45e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KEHGHMLM_01166 1.04e-104 yngA - - S - - - membrane
KEHGHMLM_01167 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KEHGHMLM_01168 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
KEHGHMLM_01170 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
KEHGHMLM_01171 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KEHGHMLM_01172 8.74e-75 ynfC - - - - - - -
KEHGHMLM_01173 1.82e-18 - - - - - - - -
KEHGHMLM_01174 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEHGHMLM_01175 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEHGHMLM_01176 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KEHGHMLM_01177 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KEHGHMLM_01178 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
KEHGHMLM_01179 1.63e-71 yneQ - - - - - - -
KEHGHMLM_01180 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
KEHGHMLM_01181 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
KEHGHMLM_01183 9.26e-10 - - - S - - - Fur-regulated basic protein B
KEHGHMLM_01184 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KEHGHMLM_01185 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KEHGHMLM_01186 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
KEHGHMLM_01187 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
KEHGHMLM_01188 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
KEHGHMLM_01189 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
KEHGHMLM_01190 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
KEHGHMLM_01191 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
KEHGHMLM_01192 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
KEHGHMLM_01193 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
KEHGHMLM_01194 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KEHGHMLM_01195 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
KEHGHMLM_01196 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KEHGHMLM_01197 1.15e-43 ynzC - - S - - - UPF0291 protein
KEHGHMLM_01198 2.29e-144 yneB - - L - - - resolvase
KEHGHMLM_01199 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KEHGHMLM_01200 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KEHGHMLM_01201 1.52e-83 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KEHGHMLM_01202 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
KEHGHMLM_01203 1.88e-174 yndL - - S - - - Replication protein
KEHGHMLM_01205 0.0 yndJ - - S - - - YndJ-like protein
KEHGHMLM_01206 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
KEHGHMLM_01207 5.29e-198 yndG - - S - - - DoxX-like family
KEHGHMLM_01208 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
KEHGHMLM_01209 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
KEHGHMLM_01210 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KEHGHMLM_01213 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
KEHGHMLM_01214 8.92e-96 - - - - - - - -
KEHGHMLM_01215 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
KEHGHMLM_01218 2.11e-170 - - - S - - - Domain of unknown function, YrpD
KEHGHMLM_01220 3.91e-210 - - - S - - - Thymidylate synthase
KEHGHMLM_01223 7.54e-22 - - - - - - - -
KEHGHMLM_01224 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
KEHGHMLM_01225 9.48e-108 - - - S - - - Protein of unknown function (DUF2691)
KEHGHMLM_01226 1.77e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEHGHMLM_01227 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KEHGHMLM_01228 2.51e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
KEHGHMLM_01229 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
KEHGHMLM_01230 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
KEHGHMLM_01231 8.66e-276 xylR - - GK - - - ROK family
KEHGHMLM_01232 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
KEHGHMLM_01233 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
KEHGHMLM_01234 1.38e-105 - - - E - - - phosphoribosylanthranilate isomerase activity
KEHGHMLM_01237 4.46e-142 - - - S - - - Domain of unknown function (DUF3885)
KEHGHMLM_01238 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KEHGHMLM_01239 3.35e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KEHGHMLM_01240 2.44e-90 - - - S - - - CAAX protease self-immunity
KEHGHMLM_01242 7.98e-124 ynaD - - J - - - Acetyltransferase (GNAT) domain
KEHGHMLM_01244 7.73e-275 - - - H - - - N-terminal domain of galactosyltransferase
KEHGHMLM_01245 5.26e-202 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KEHGHMLM_01246 2.22e-47 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KEHGHMLM_01247 1.79e-74 - - - S - - - Bacteriophage holin family
KEHGHMLM_01248 1.92e-120 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
KEHGHMLM_01249 8.33e-77 - - - L - - - Belongs to the 'phage' integrase family
KEHGHMLM_01250 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KEHGHMLM_01251 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
KEHGHMLM_01252 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KEHGHMLM_01253 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KEHGHMLM_01254 9.33e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
KEHGHMLM_01255 2.23e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KEHGHMLM_01256 2.24e-141 - - - - - - - -
KEHGHMLM_01257 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEHGHMLM_01258 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEHGHMLM_01259 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KEHGHMLM_01260 1.2e-30 ymzA - - - - - - -
KEHGHMLM_01261 1.63e-31 - - - - - - - -
KEHGHMLM_01262 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KEHGHMLM_01263 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KEHGHMLM_01264 5.41e-76 ymaF - - S - - - YmaF family
KEHGHMLM_01266 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KEHGHMLM_01267 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
KEHGHMLM_01268 1.47e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
KEHGHMLM_01269 3.96e-163 ymaC - - S - - - Replication protein
KEHGHMLM_01271 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
KEHGHMLM_01272 1.09e-206 - - - S - - - Metallo-beta-lactamase superfamily
KEHGHMLM_01273 3.27e-80 ymzB - - - - - - -
KEHGHMLM_01274 8.33e-296 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KEHGHMLM_01275 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
KEHGHMLM_01276 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KEHGHMLM_01277 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KEHGHMLM_01278 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
KEHGHMLM_01279 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
KEHGHMLM_01280 1.05e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
KEHGHMLM_01281 1.44e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
KEHGHMLM_01282 1.13e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
KEHGHMLM_01283 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KEHGHMLM_01284 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
KEHGHMLM_01285 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KEHGHMLM_01286 1.64e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
KEHGHMLM_01288 1.78e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KEHGHMLM_01289 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
KEHGHMLM_01290 2.94e-141 pksA - - K - - - Transcriptional regulator
KEHGHMLM_01291 1.38e-127 ymcC - - S - - - Membrane
KEHGHMLM_01292 6.68e-92 - - - S - - - Regulatory protein YrvL
KEHGHMLM_01293 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KEHGHMLM_01294 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KEHGHMLM_01295 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
KEHGHMLM_01296 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KEHGHMLM_01297 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KEHGHMLM_01298 4.15e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KEHGHMLM_01299 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KEHGHMLM_01300 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
KEHGHMLM_01301 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
KEHGHMLM_01302 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KEHGHMLM_01303 4e-280 pbpX - - V - - - Beta-lactamase
KEHGHMLM_01304 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KEHGHMLM_01305 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KEHGHMLM_01306 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEHGHMLM_01307 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
KEHGHMLM_01308 5.56e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
KEHGHMLM_01309 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
KEHGHMLM_01310 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KEHGHMLM_01311 2.37e-309 ymfH - - S - - - zinc protease
KEHGHMLM_01312 9.47e-299 albE - - S - - - Peptidase M16
KEHGHMLM_01313 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_01314 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_01315 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KEHGHMLM_01316 4.94e-44 - - - S - - - YlzJ-like protein
KEHGHMLM_01317 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
KEHGHMLM_01318 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEHGHMLM_01319 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KEHGHMLM_01320 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KEHGHMLM_01321 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KEHGHMLM_01322 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KEHGHMLM_01323 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
KEHGHMLM_01324 1.53e-56 ymxH - - S - - - YlmC YmxH family
KEHGHMLM_01325 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
KEHGHMLM_01326 2.06e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
KEHGHMLM_01327 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KEHGHMLM_01328 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KEHGHMLM_01329 1.1e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KEHGHMLM_01330 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KEHGHMLM_01331 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KEHGHMLM_01332 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
KEHGHMLM_01333 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KEHGHMLM_01334 6.16e-63 ylxQ - - J - - - ribosomal protein
KEHGHMLM_01335 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
KEHGHMLM_01336 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KEHGHMLM_01337 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KEHGHMLM_01338 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEHGHMLM_01339 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KEHGHMLM_01340 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KEHGHMLM_01341 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KEHGHMLM_01342 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KEHGHMLM_01343 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KEHGHMLM_01344 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KEHGHMLM_01345 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KEHGHMLM_01346 8.06e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KEHGHMLM_01347 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KEHGHMLM_01348 6.62e-99 ylxL - - - - - - -
KEHGHMLM_01349 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_01350 1.36e-111 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KEHGHMLM_01351 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KEHGHMLM_01352 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
KEHGHMLM_01353 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
KEHGHMLM_01354 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KEHGHMLM_01355 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
KEHGHMLM_01356 9.37e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
KEHGHMLM_01357 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KEHGHMLM_01358 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KEHGHMLM_01359 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
KEHGHMLM_01360 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
KEHGHMLM_01361 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
KEHGHMLM_01362 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
KEHGHMLM_01363 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
KEHGHMLM_01364 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KEHGHMLM_01365 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KEHGHMLM_01366 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
KEHGHMLM_01367 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
KEHGHMLM_01368 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
KEHGHMLM_01369 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
KEHGHMLM_01370 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
KEHGHMLM_01371 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
KEHGHMLM_01372 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KEHGHMLM_01373 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
KEHGHMLM_01374 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KEHGHMLM_01375 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
KEHGHMLM_01376 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
KEHGHMLM_01377 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
KEHGHMLM_01378 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KEHGHMLM_01379 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KEHGHMLM_01380 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KEHGHMLM_01381 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KEHGHMLM_01382 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
KEHGHMLM_01383 4.47e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KEHGHMLM_01384 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEHGHMLM_01385 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
KEHGHMLM_01386 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KEHGHMLM_01387 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KEHGHMLM_01388 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
KEHGHMLM_01389 0.0 ylqG - - - - - - -
KEHGHMLM_01390 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEHGHMLM_01391 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KEHGHMLM_01392 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KEHGHMLM_01393 6.9e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KEHGHMLM_01394 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KEHGHMLM_01395 9.77e-80 ylqD - - S - - - YlqD protein
KEHGHMLM_01396 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KEHGHMLM_01397 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KEHGHMLM_01398 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KEHGHMLM_01399 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KEHGHMLM_01400 1.38e-113 - - - - - - - -
KEHGHMLM_01401 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KEHGHMLM_01402 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KEHGHMLM_01403 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KEHGHMLM_01404 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KEHGHMLM_01405 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KEHGHMLM_01406 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
KEHGHMLM_01407 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KEHGHMLM_01408 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KEHGHMLM_01409 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KEHGHMLM_01410 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KEHGHMLM_01411 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KEHGHMLM_01412 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KEHGHMLM_01413 3.65e-78 yloU - - S - - - protein conserved in bacteria
KEHGHMLM_01414 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KEHGHMLM_01415 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KEHGHMLM_01416 1.91e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KEHGHMLM_01417 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KEHGHMLM_01418 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KEHGHMLM_01419 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KEHGHMLM_01420 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KEHGHMLM_01421 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KEHGHMLM_01422 3.51e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KEHGHMLM_01423 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEHGHMLM_01424 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEHGHMLM_01425 5.98e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KEHGHMLM_01426 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KEHGHMLM_01427 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KEHGHMLM_01428 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
KEHGHMLM_01429 1.19e-201 yloC - - S - - - stress-induced protein
KEHGHMLM_01430 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
KEHGHMLM_01431 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KEHGHMLM_01432 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
KEHGHMLM_01433 1.69e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
KEHGHMLM_01434 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KEHGHMLM_01435 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KEHGHMLM_01436 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KEHGHMLM_01437 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
KEHGHMLM_01438 1.03e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KEHGHMLM_01440 1.22e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KEHGHMLM_01441 1.09e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KEHGHMLM_01442 1.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KEHGHMLM_01443 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KEHGHMLM_01444 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
KEHGHMLM_01445 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KEHGHMLM_01446 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KEHGHMLM_01447 2.44e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KEHGHMLM_01448 6.15e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
KEHGHMLM_01449 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KEHGHMLM_01450 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KEHGHMLM_01451 6.39e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KEHGHMLM_01452 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
KEHGHMLM_01453 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KEHGHMLM_01454 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KEHGHMLM_01455 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
KEHGHMLM_01456 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
KEHGHMLM_01457 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KEHGHMLM_01458 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KEHGHMLM_01459 3.73e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
KEHGHMLM_01460 1.46e-50 ylmC - - S - - - sporulation protein
KEHGHMLM_01461 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
KEHGHMLM_01462 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KEHGHMLM_01463 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_01464 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_01465 2.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KEHGHMLM_01466 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
KEHGHMLM_01467 2.14e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KEHGHMLM_01468 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KEHGHMLM_01469 5.37e-76 sbp - - S - - - small basic protein
KEHGHMLM_01470 1.06e-132 ylxX - - S - - - protein conserved in bacteria
KEHGHMLM_01471 2.23e-142 ylxW - - S - - - protein conserved in bacteria
KEHGHMLM_01472 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KEHGHMLM_01473 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KEHGHMLM_01474 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KEHGHMLM_01475 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KEHGHMLM_01476 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KEHGHMLM_01477 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KEHGHMLM_01478 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KEHGHMLM_01479 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
KEHGHMLM_01480 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KEHGHMLM_01481 3.42e-68 ftsL - - D - - - Essential cell division protein
KEHGHMLM_01482 1.94e-217 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KEHGHMLM_01483 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KEHGHMLM_01484 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KEHGHMLM_01485 7.58e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEHGHMLM_01486 1.33e-115 ylbP - - K - - - n-acetyltransferase
KEHGHMLM_01487 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KEHGHMLM_01488 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KEHGHMLM_01489 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KEHGHMLM_01491 3.29e-298 ylbM - - S - - - Belongs to the UPF0348 family
KEHGHMLM_01492 2.24e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KEHGHMLM_01493 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
KEHGHMLM_01494 3.18e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
KEHGHMLM_01495 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KEHGHMLM_01496 3.51e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KEHGHMLM_01497 5.1e-51 ylbG - - S - - - UPF0298 protein
KEHGHMLM_01498 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
KEHGHMLM_01499 1.73e-48 ylbE - - S - - - YlbE-like protein
KEHGHMLM_01500 3.24e-89 ylbD - - S - - - Putative coat protein
KEHGHMLM_01501 6.24e-256 ylbC - - S - - - protein with SCP PR1 domains
KEHGHMLM_01502 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
KEHGHMLM_01503 1.61e-81 ylbA - - S - - - YugN-like family
KEHGHMLM_01504 4.06e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
KEHGHMLM_01505 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KEHGHMLM_01506 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KEHGHMLM_01507 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KEHGHMLM_01508 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KEHGHMLM_01509 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KEHGHMLM_01510 2e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KEHGHMLM_01511 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KEHGHMLM_01512 3.49e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KEHGHMLM_01513 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
KEHGHMLM_01514 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KEHGHMLM_01515 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KEHGHMLM_01516 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
KEHGHMLM_01517 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEHGHMLM_01518 8.92e-44 ylaI - - S - - - protein conserved in bacteria
KEHGHMLM_01519 1.26e-62 ylaH - - S - - - YlaH-like protein
KEHGHMLM_01520 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KEHGHMLM_01521 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
KEHGHMLM_01522 1.74e-57 ylaE - - - - - - -
KEHGHMLM_01524 3.56e-51 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_01525 1.44e-56 ylaB - - - - - - -
KEHGHMLM_01526 0.0 ylaA - - - - - - -
KEHGHMLM_01527 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KEHGHMLM_01528 8.61e-222 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KEHGHMLM_01529 1.21e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
KEHGHMLM_01530 1.91e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
KEHGHMLM_01531 4.48e-35 ykzI - - - - - - -
KEHGHMLM_01532 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
KEHGHMLM_01533 2.22e-55 yktA - - S - - - Belongs to the UPF0223 family
KEHGHMLM_01534 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
KEHGHMLM_01535 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
KEHGHMLM_01536 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEHGHMLM_01537 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEHGHMLM_01538 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEHGHMLM_01539 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEHGHMLM_01540 2.22e-140 ykyA - - L - - - Putative cell-wall binding lipoprotein
KEHGHMLM_01541 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KEHGHMLM_01542 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEHGHMLM_01543 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
KEHGHMLM_01544 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
KEHGHMLM_01545 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEHGHMLM_01546 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KEHGHMLM_01547 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KEHGHMLM_01548 6.63e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
KEHGHMLM_01549 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KEHGHMLM_01550 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
KEHGHMLM_01551 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
KEHGHMLM_01552 1.09e-18 - - - S - - - Uncharacterized protein YkpC
KEHGHMLM_01553 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KEHGHMLM_01554 3.9e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEHGHMLM_01555 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEHGHMLM_01556 5.43e-52 ykoA - - - - - - -
KEHGHMLM_01557 1.42e-133 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KEHGHMLM_01558 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KEHGHMLM_01559 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
KEHGHMLM_01560 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_01561 3.33e-266 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KEHGHMLM_01562 8.67e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_01563 3.32e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KEHGHMLM_01564 1.31e-150 yknW - - S - - - Yip1 domain
KEHGHMLM_01565 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KEHGHMLM_01566 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KEHGHMLM_01567 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KEHGHMLM_01568 2.22e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
KEHGHMLM_01569 7.8e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KEHGHMLM_01570 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
KEHGHMLM_01571 1.47e-242 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KEHGHMLM_01572 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KEHGHMLM_01573 5.72e-199 yknT - - - ko:K06437 - ko00000 -
KEHGHMLM_01574 4.71e-122 rok - - K - - - Repressor of ComK
KEHGHMLM_01575 1.47e-104 ykuV - - CO - - - thiol-disulfide
KEHGHMLM_01576 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
KEHGHMLM_01577 8.27e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
KEHGHMLM_01578 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
KEHGHMLM_01579 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KEHGHMLM_01580 1.52e-124 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KEHGHMLM_01581 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
KEHGHMLM_01582 7.7e-226 ykuO - - - - - - -
KEHGHMLM_01583 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
KEHGHMLM_01584 6.52e-216 ccpC - - K - - - Transcriptional regulator
KEHGHMLM_01585 5.15e-100 ykuL - - S - - - CBS domain
KEHGHMLM_01586 7.83e-38 ykzF - - S - - - Antirepressor AbbA
KEHGHMLM_01587 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
KEHGHMLM_01588 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
KEHGHMLM_01589 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
KEHGHMLM_01590 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_01591 2.01e-211 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
KEHGHMLM_01592 5.84e-115 ykuD - - S - - - protein conserved in bacteria
KEHGHMLM_01593 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_01594 3.71e-110 ykyB - - S - - - YkyB-like protein
KEHGHMLM_01595 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
KEHGHMLM_01596 1.05e-22 - - - - - - - -
KEHGHMLM_01597 1.63e-280 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KEHGHMLM_01598 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_01599 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KEHGHMLM_01600 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
KEHGHMLM_01601 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KEHGHMLM_01602 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_01603 5.32e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_01604 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
KEHGHMLM_01605 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_01606 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KEHGHMLM_01607 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
KEHGHMLM_01608 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_01609 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
KEHGHMLM_01611 3.28e-230 ykvZ - - K - - - Transcriptional regulator
KEHGHMLM_01612 1.11e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
KEHGHMLM_01613 3.99e-09 - - - - - - - -
KEHGHMLM_01614 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KEHGHMLM_01615 5.57e-115 stoA - - CO - - - thiol-disulfide
KEHGHMLM_01616 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEHGHMLM_01617 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
KEHGHMLM_01618 2.6e-39 - - - - - - - -
KEHGHMLM_01619 5.43e-35 ykvS - - S - - - protein conserved in bacteria
KEHGHMLM_01620 1.09e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
KEHGHMLM_01621 3.02e-205 - - - G - - - Glycosyl hydrolases family 18
KEHGHMLM_01622 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
KEHGHMLM_01623 6.07e-272 - - - M - - - Glycosyl transferases group 1
KEHGHMLM_01624 3.81e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KEHGHMLM_01625 3.53e-81 ykvN - - K - - - Transcriptional regulator
KEHGHMLM_01626 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KEHGHMLM_01627 1.45e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KEHGHMLM_01628 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KEHGHMLM_01629 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KEHGHMLM_01630 6.76e-227 ykvI - - S - - - membrane
KEHGHMLM_01631 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KEHGHMLM_01632 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
KEHGHMLM_01633 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
KEHGHMLM_01634 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
KEHGHMLM_01635 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KEHGHMLM_01636 1.96e-93 eag - - - - - - -
KEHGHMLM_01638 2.53e-67 - - - S - - - Protein of unknown function (DUF1232)
KEHGHMLM_01639 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KEHGHMLM_01640 1.06e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KEHGHMLM_01641 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KEHGHMLM_01642 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KEHGHMLM_01643 6.03e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KEHGHMLM_01644 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KEHGHMLM_01645 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KEHGHMLM_01646 2.2e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KEHGHMLM_01648 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEHGHMLM_01649 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_01650 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
KEHGHMLM_01651 2.51e-28 ykzE - - - - - - -
KEHGHMLM_01653 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
KEHGHMLM_01654 1.61e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KEHGHMLM_01655 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
KEHGHMLM_01656 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
KEHGHMLM_01657 1.27e-209 rsgI - - S - - - Anti-sigma factor N-terminus
KEHGHMLM_01658 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_01659 6.3e-225 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KEHGHMLM_01660 2.08e-144 ykoX - - S - - - membrane-associated protein
KEHGHMLM_01661 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
KEHGHMLM_01662 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KEHGHMLM_01663 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
KEHGHMLM_01664 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KEHGHMLM_01665 0.0 ykoS - - - - - - -
KEHGHMLM_01666 2.52e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
KEHGHMLM_01667 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
KEHGHMLM_01668 3.88e-271 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KEHGHMLM_01669 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
KEHGHMLM_01670 3.04e-36 ykoL - - - - - - -
KEHGHMLM_01671 1.63e-25 - - - - - - - -
KEHGHMLM_01672 1.49e-70 tnrA - - K - - - transcriptional
KEHGHMLM_01673 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
KEHGHMLM_01675 1.45e-08 - - - - - - - -
KEHGHMLM_01676 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
KEHGHMLM_01677 5.55e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
KEHGHMLM_01678 4.97e-306 ykoH - - T - - - Histidine kinase
KEHGHMLM_01679 4.3e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_01680 2.01e-141 ykoF - - S - - - YKOF-related Family
KEHGHMLM_01681 1.98e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KEHGHMLM_01682 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_01683 7.36e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KEHGHMLM_01684 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEHGHMLM_01685 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KEHGHMLM_01686 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KEHGHMLM_01687 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
KEHGHMLM_01688 3.32e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
KEHGHMLM_01689 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
KEHGHMLM_01690 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
KEHGHMLM_01691 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KEHGHMLM_01692 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEHGHMLM_01693 4.77e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KEHGHMLM_01694 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
KEHGHMLM_01695 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
KEHGHMLM_01696 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEHGHMLM_01697 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
KEHGHMLM_01698 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
KEHGHMLM_01699 3.55e-14 - - - - - - - -
KEHGHMLM_01700 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KEHGHMLM_01701 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
KEHGHMLM_01702 1.78e-205 ykgA - - E - - - Amidinotransferase
KEHGHMLM_01703 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
KEHGHMLM_01704 2.82e-235 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_01705 1.53e-211 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KEHGHMLM_01706 4.85e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KEHGHMLM_01707 2.64e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KEHGHMLM_01708 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KEHGHMLM_01709 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_01710 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEHGHMLM_01711 2.28e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEHGHMLM_01712 9.45e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
KEHGHMLM_01713 8.2e-179 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
KEHGHMLM_01714 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEHGHMLM_01716 6.35e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KEHGHMLM_01717 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEHGHMLM_01718 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KEHGHMLM_01719 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
KEHGHMLM_01720 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
KEHGHMLM_01721 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
KEHGHMLM_01722 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
KEHGHMLM_01723 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
KEHGHMLM_01725 1.85e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
KEHGHMLM_01726 3.87e-51 xhlB - - S - - - SPP1 phage holin
KEHGHMLM_01727 2.21e-51 xhlA - - S - - - Haemolysin XhlA
KEHGHMLM_01728 2.21e-193 xepA - - - - - - -
KEHGHMLM_01729 6.35e-31 xkdX - - - - - - -
KEHGHMLM_01730 3.67e-59 xkdW - - S - - - XkdW protein
KEHGHMLM_01731 0.0 - - - - - - - -
KEHGHMLM_01732 8.94e-56 - - - - - - - -
KEHGHMLM_01733 6.51e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KEHGHMLM_01734 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KEHGHMLM_01735 1.56e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
KEHGHMLM_01736 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
KEHGHMLM_01737 2.31e-232 xkdQ - - G - - - NLP P60 protein
KEHGHMLM_01738 1.7e-156 xkdP - - S - - - Lysin motif
KEHGHMLM_01739 0.0 xkdO - - L - - - Transglycosylase SLT domain
KEHGHMLM_01740 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
KEHGHMLM_01741 6.01e-99 xkdM - - S - - - Phage tail tube protein
KEHGHMLM_01742 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
KEHGHMLM_01743 2.87e-101 xkdJ - - - - - - -
KEHGHMLM_01744 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
KEHGHMLM_01745 3.02e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
KEHGHMLM_01746 9.07e-80 yqbG - - S - - - Protein of unknown function (DUF3199)
KEHGHMLM_01747 3.91e-217 xkdG - - S - - - Phage capsid family
KEHGHMLM_01748 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
KEHGHMLM_01749 0.0 yqbA - - S - - - portal protein
KEHGHMLM_01750 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
KEHGHMLM_01751 1.6e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
KEHGHMLM_01752 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KEHGHMLM_01756 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
KEHGHMLM_01757 5.09e-201 xkdB - - K - - - sequence-specific DNA binding
KEHGHMLM_01759 8.21e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
KEHGHMLM_01760 8.53e-142 xkdA - - E - - - IrrE N-terminal-like domain
KEHGHMLM_01761 1.3e-203 yjqC - - P ko:K07217 - ko00000 Catalase
KEHGHMLM_01762 9.94e-142 yjqB - - S - - - Pfam:DUF867
KEHGHMLM_01763 1.07e-77 yjqA - - S - - - Bacterial PH domain
KEHGHMLM_01764 7.58e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KEHGHMLM_01765 1.79e-55 - - - S - - - YCII-related domain
KEHGHMLM_01767 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KEHGHMLM_01768 7.1e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
KEHGHMLM_01769 2.71e-103 yjoA - - S - - - DinB family
KEHGHMLM_01770 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
KEHGHMLM_01771 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KEHGHMLM_01772 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
KEHGHMLM_01773 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
KEHGHMLM_01774 5.58e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
KEHGHMLM_01775 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_01776 2.27e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
KEHGHMLM_01777 4.91e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
KEHGHMLM_01778 2e-239 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
KEHGHMLM_01779 2.92e-312 - - - G ko:K03292 - ko00000 symporter YjmB
KEHGHMLM_01780 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
KEHGHMLM_01781 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KEHGHMLM_01782 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
KEHGHMLM_01783 2.46e-118 yjlB - - S - - - Cupin domain
KEHGHMLM_01784 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
KEHGHMLM_01785 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KEHGHMLM_01786 5.23e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
KEHGHMLM_01787 2.79e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
KEHGHMLM_01788 1.11e-41 - - - - - - - -
KEHGHMLM_01789 5.05e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KEHGHMLM_01790 2.74e-285 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KEHGHMLM_01792 1.57e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KEHGHMLM_01794 2.65e-121 yjgD - - S - - - Protein of unknown function (DUF1641)
KEHGHMLM_01795 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
KEHGHMLM_01796 1e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
KEHGHMLM_01797 7.98e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
KEHGHMLM_01798 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
KEHGHMLM_01799 1.13e-29 yjfB - - S - - - Putative motility protein
KEHGHMLM_01800 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
KEHGHMLM_01801 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
KEHGHMLM_01803 1.25e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KEHGHMLM_01804 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
KEHGHMLM_01805 5.97e-39 - - - S - - - Domain of unknown function (DUF4177)
KEHGHMLM_01806 2.89e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KEHGHMLM_01808 2.54e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KEHGHMLM_01809 5.34e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
KEHGHMLM_01810 1.03e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KEHGHMLM_01811 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_01812 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
KEHGHMLM_01813 0.000141 - - - - - - - -
KEHGHMLM_01814 1.14e-179 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KEHGHMLM_01815 7.38e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
KEHGHMLM_01816 4.96e-160 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KEHGHMLM_01820 9.15e-312 - - - M - - - nucleic acid phosphodiester bond hydrolysis
KEHGHMLM_01821 6.59e-41 - - - - - - - -
KEHGHMLM_01822 2.03e-43 - - - - - - - -
KEHGHMLM_01823 4.28e-21 - - - - - - - -
KEHGHMLM_01825 1.74e-272 yjcL - - S - - - Protein of unknown function (DUF819)
KEHGHMLM_01826 9.74e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
KEHGHMLM_01827 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KEHGHMLM_01828 4.65e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KEHGHMLM_01829 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
KEHGHMLM_01830 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
KEHGHMLM_01831 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_01832 2.12e-49 - - - - - - - -
KEHGHMLM_01833 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KEHGHMLM_01834 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
KEHGHMLM_01837 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
KEHGHMLM_01838 6.69e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
KEHGHMLM_01839 9.3e-32 cotW - - - ko:K06341 - ko00000 -
KEHGHMLM_01840 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
KEHGHMLM_01841 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
KEHGHMLM_01842 4.76e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
KEHGHMLM_01843 8.5e-103 yjbX - - S - - - Spore coat protein
KEHGHMLM_01844 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KEHGHMLM_01845 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KEHGHMLM_01846 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KEHGHMLM_01847 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KEHGHMLM_01848 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
KEHGHMLM_01849 1.22e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
KEHGHMLM_01850 2.71e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
KEHGHMLM_01851 8.1e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KEHGHMLM_01852 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KEHGHMLM_01853 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KEHGHMLM_01854 2.58e-203 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KEHGHMLM_01855 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEHGHMLM_01856 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
KEHGHMLM_01857 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
KEHGHMLM_01858 2.98e-129 yjbK - - S - - - protein conserved in bacteria
KEHGHMLM_01859 9.78e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KEHGHMLM_01860 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
KEHGHMLM_01861 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KEHGHMLM_01863 2.68e-28 - - - - - - - -
KEHGHMLM_01864 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KEHGHMLM_01865 2.53e-281 coiA - - S ko:K06198 - ko00000 Competence protein
KEHGHMLM_01866 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KEHGHMLM_01867 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
KEHGHMLM_01868 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KEHGHMLM_01869 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_01870 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
KEHGHMLM_01871 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_01872 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_01873 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEHGHMLM_01874 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEHGHMLM_01875 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KEHGHMLM_01876 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KEHGHMLM_01877 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
KEHGHMLM_01878 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEHGHMLM_01879 1.36e-215 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KEHGHMLM_01880 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
KEHGHMLM_01881 4.01e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_01882 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_01883 3.17e-191 yjaZ - - O - - - Zn-dependent protease
KEHGHMLM_01884 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KEHGHMLM_01885 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEHGHMLM_01886 2.66e-35 yjzB - - - - - - -
KEHGHMLM_01887 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
KEHGHMLM_01888 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
KEHGHMLM_01889 6.08e-131 yjaV - - - - - - -
KEHGHMLM_01890 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
KEHGHMLM_01891 1.53e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
KEHGHMLM_01892 2.51e-39 yjzC - - S - - - YjzC-like protein
KEHGHMLM_01893 1.74e-224 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KEHGHMLM_01894 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
KEHGHMLM_01895 7.78e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KEHGHMLM_01896 9.77e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KEHGHMLM_01897 1.48e-174 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KEHGHMLM_01898 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KEHGHMLM_01899 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KEHGHMLM_01900 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
KEHGHMLM_01901 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
KEHGHMLM_01902 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
KEHGHMLM_01903 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
KEHGHMLM_01904 8.38e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KEHGHMLM_01905 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KEHGHMLM_01906 1.92e-08 - - - - - - - -
KEHGHMLM_01907 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
KEHGHMLM_01908 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
KEHGHMLM_01909 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KEHGHMLM_01910 9.13e-202 yitS - - S - - - protein conserved in bacteria
KEHGHMLM_01911 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
KEHGHMLM_01912 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
KEHGHMLM_01913 1.29e-121 - - - - - - - -
KEHGHMLM_01914 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
KEHGHMLM_01915 2.31e-127 - - - S - - - Sporulation delaying protein SdpA
KEHGHMLM_01916 1.66e-217 - - - - - - - -
KEHGHMLM_01917 4.16e-122 - - - - - - - -
KEHGHMLM_01918 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
KEHGHMLM_01919 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
KEHGHMLM_01920 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KEHGHMLM_01921 1.99e-89 - - - S - - - Acetyltransferase (GNAT) domain
KEHGHMLM_01922 3.03e-195 yitH - - K - - - Acetyltransferase (GNAT) domain
KEHGHMLM_01923 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_01924 1.97e-279 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KEHGHMLM_01925 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KEHGHMLM_01926 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
KEHGHMLM_01927 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
KEHGHMLM_01928 2.15e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
KEHGHMLM_01929 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
KEHGHMLM_01930 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KEHGHMLM_01931 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEHGHMLM_01932 2.5e-95 yisX - - S - - - Pentapeptide repeats (9 copies)
KEHGHMLM_01933 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEHGHMLM_01934 2.08e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
KEHGHMLM_01935 9.94e-120 yisT - - S - - - DinB family
KEHGHMLM_01936 5.17e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KEHGHMLM_01937 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KEHGHMLM_01938 1.41e-207 yisR - - K - - - Transcriptional regulator
KEHGHMLM_01939 1.01e-310 yisQ - - V - - - Mate efflux family protein
KEHGHMLM_01940 1.8e-188 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
KEHGHMLM_01941 4.38e-114 yizA - - S - - - Damage-inducible protein DinB
KEHGHMLM_01942 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KEHGHMLM_01943 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
KEHGHMLM_01944 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KEHGHMLM_01945 1.02e-74 yisL - - S - - - UPF0344 protein
KEHGHMLM_01946 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KEHGHMLM_01947 2.29e-223 cotH - - M ko:K06330 - ko00000 Spore Coat
KEHGHMLM_01948 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
KEHGHMLM_01949 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
KEHGHMLM_01950 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
KEHGHMLM_01951 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
KEHGHMLM_01952 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
KEHGHMLM_01953 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
KEHGHMLM_01954 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
KEHGHMLM_01955 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
KEHGHMLM_01956 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
KEHGHMLM_01957 1.63e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KEHGHMLM_01958 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KEHGHMLM_01959 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
KEHGHMLM_01960 2.19e-100 yhjR - - S - - - Rubrerythrin
KEHGHMLM_01961 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
KEHGHMLM_01962 4.25e-271 - - - EGP - - - Transmembrane secretion effector
KEHGHMLM_01963 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
KEHGHMLM_01964 4.36e-239 yhjM - - K - - - Transcriptional regulator
KEHGHMLM_01965 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KEHGHMLM_01966 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
KEHGHMLM_01967 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
KEHGHMLM_01968 2.57e-272 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
KEHGHMLM_01969 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_01970 0.0 yhjG - - CH - - - FAD binding domain
KEHGHMLM_01971 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KEHGHMLM_01972 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
KEHGHMLM_01973 2.12e-77 yhjD - - - - - - -
KEHGHMLM_01974 9.31e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
KEHGHMLM_01975 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEHGHMLM_01976 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
KEHGHMLM_01977 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KEHGHMLM_01978 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
KEHGHMLM_01979 9.84e-45 yhzC - - S - - - IDEAL
KEHGHMLM_01980 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_01981 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
KEHGHMLM_01982 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
KEHGHMLM_01983 1.21e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KEHGHMLM_01984 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KEHGHMLM_01985 7.05e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KEHGHMLM_01986 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
KEHGHMLM_01987 2.27e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KEHGHMLM_01988 1.39e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
KEHGHMLM_01989 8.5e-100 - - - K - - - acetyltransferase
KEHGHMLM_01990 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KEHGHMLM_01991 9.64e-308 yhfN - - O - - - Peptidase M48
KEHGHMLM_01992 5.6e-85 yhfM - - - - - - -
KEHGHMLM_01993 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
KEHGHMLM_01994 1.01e-141 yhfK - - GM - - - NmrA-like family
KEHGHMLM_01995 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KEHGHMLM_01996 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KEHGHMLM_01997 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEHGHMLM_01998 6.22e-93 - - - S - - - ASCH
KEHGHMLM_01999 2.68e-253 yhfE - - G - - - peptidase M42
KEHGHMLM_02000 1.88e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
KEHGHMLM_02001 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEHGHMLM_02002 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
KEHGHMLM_02003 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_02004 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KEHGHMLM_02005 2.4e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KEHGHMLM_02006 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KEHGHMLM_02007 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KEHGHMLM_02008 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KEHGHMLM_02009 8.22e-44 - - - C - - - Rubrerythrin
KEHGHMLM_02010 3.01e-309 yhfA - - C - - - membrane
KEHGHMLM_02011 3.63e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KEHGHMLM_02012 3.37e-160 ecsC - - S - - - EcsC protein family
KEHGHMLM_02013 7.32e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KEHGHMLM_02014 1.1e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
KEHGHMLM_02015 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KEHGHMLM_02016 6.16e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KEHGHMLM_02017 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
KEHGHMLM_02018 9.66e-30 - - - - - - - -
KEHGHMLM_02019 1.74e-54 yhaH - - S - - - YtxH-like protein
KEHGHMLM_02020 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
KEHGHMLM_02021 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
KEHGHMLM_02022 1.4e-116 yhaK - - S - - - Putative zincin peptidase
KEHGHMLM_02023 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KEHGHMLM_02024 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
KEHGHMLM_02025 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
KEHGHMLM_02026 0.0 yhaN - - L - - - AAA domain
KEHGHMLM_02027 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
KEHGHMLM_02028 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
KEHGHMLM_02029 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02030 2.29e-36 - - - S - - - YhzD-like protein
KEHGHMLM_02031 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
KEHGHMLM_02033 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
KEHGHMLM_02034 2.63e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
KEHGHMLM_02035 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
KEHGHMLM_02036 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
KEHGHMLM_02037 1.58e-262 yhaZ - - L - - - DNA alkylation repair enzyme
KEHGHMLM_02038 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
KEHGHMLM_02039 1.69e-258 yheB - - S - - - Belongs to the UPF0754 family
KEHGHMLM_02040 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
KEHGHMLM_02041 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
KEHGHMLM_02042 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
KEHGHMLM_02043 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
KEHGHMLM_02044 3.31e-143 yheG - - GM - - - NAD(P)H-binding
KEHGHMLM_02045 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KEHGHMLM_02046 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KEHGHMLM_02047 5.24e-107 nhaX - - T - - - Belongs to the universal stress protein A family
KEHGHMLM_02048 1.4e-300 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
KEHGHMLM_02049 3.69e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KEHGHMLM_02050 5.47e-198 nodB1 - - G - - - deacetylase
KEHGHMLM_02051 4.66e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KEHGHMLM_02052 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
KEHGHMLM_02053 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
KEHGHMLM_02054 1.82e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KEHGHMLM_02055 1.43e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEHGHMLM_02056 4.47e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEHGHMLM_02057 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
KEHGHMLM_02058 1.63e-280 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KEHGHMLM_02059 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
KEHGHMLM_02060 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KEHGHMLM_02061 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KEHGHMLM_02062 3.9e-243 yhdN - - C - - - Aldo keto reductase
KEHGHMLM_02063 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_02064 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
KEHGHMLM_02065 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
KEHGHMLM_02066 8.33e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_02067 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEHGHMLM_02068 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KEHGHMLM_02069 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
KEHGHMLM_02070 1.3e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_02071 2.15e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KEHGHMLM_02072 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_02073 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KEHGHMLM_02074 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KEHGHMLM_02075 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
KEHGHMLM_02076 1.51e-306 ygxB - - M - - - Conserved TM helix
KEHGHMLM_02077 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
KEHGHMLM_02078 1.2e-268 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
KEHGHMLM_02079 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
KEHGHMLM_02080 1.65e-51 yhdB - - S - - - YhdB-like protein
KEHGHMLM_02081 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
KEHGHMLM_02082 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_02083 2.19e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_02084 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KEHGHMLM_02085 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KEHGHMLM_02086 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KEHGHMLM_02087 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KEHGHMLM_02088 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KEHGHMLM_02089 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEHGHMLM_02090 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KEHGHMLM_02091 4.32e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
KEHGHMLM_02092 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
KEHGHMLM_02093 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
KEHGHMLM_02094 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KEHGHMLM_02095 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
KEHGHMLM_02096 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KEHGHMLM_02097 1.68e-146 yhcQ - - M - - - Spore coat protein
KEHGHMLM_02098 3.64e-223 yhcP - - - - - - -
KEHGHMLM_02099 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEHGHMLM_02100 1.13e-70 yhcM - - - - - - -
KEHGHMLM_02101 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEHGHMLM_02102 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
KEHGHMLM_02103 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KEHGHMLM_02104 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
KEHGHMLM_02105 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEHGHMLM_02106 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02107 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02108 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_02109 2.92e-69 - - - - - - - -
KEHGHMLM_02110 3.95e-59 yhcC - - - - - - -
KEHGHMLM_02111 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
KEHGHMLM_02112 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
KEHGHMLM_02113 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
KEHGHMLM_02114 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
KEHGHMLM_02115 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
KEHGHMLM_02116 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
KEHGHMLM_02117 4.06e-103 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KEHGHMLM_02118 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
KEHGHMLM_02119 2.29e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
KEHGHMLM_02120 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KEHGHMLM_02121 2.28e-224 yhbB - - S - - - Putative amidase domain
KEHGHMLM_02122 8.1e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KEHGHMLM_02123 5.51e-147 yhzB - - S - - - B3/4 domain
KEHGHMLM_02125 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_02126 2.79e-102 ygaO - - - - - - -
KEHGHMLM_02127 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEHGHMLM_02129 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
KEHGHMLM_02130 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KEHGHMLM_02131 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
KEHGHMLM_02132 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KEHGHMLM_02133 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KEHGHMLM_02135 0.0 ygaK - - C - - - Berberine and berberine like
KEHGHMLM_02136 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KEHGHMLM_02137 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KEHGHMLM_02138 3.88e-37 - - - - - - - -
KEHGHMLM_02139 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
KEHGHMLM_02147 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
KEHGHMLM_02148 3.31e-120 - - - M - - - FR47-like protein
KEHGHMLM_02149 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
KEHGHMLM_02150 8e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
KEHGHMLM_02151 1.95e-109 yuaE - - S - - - DinB superfamily
KEHGHMLM_02152 8.58e-139 yuaD - - - - - - -
KEHGHMLM_02153 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
KEHGHMLM_02154 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KEHGHMLM_02155 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
KEHGHMLM_02156 5.83e-118 yuaB - - - - - - -
KEHGHMLM_02157 6.13e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KEHGHMLM_02158 8.78e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
KEHGHMLM_02159 3.31e-52 yubF - - S - - - yiaA/B two helix domain
KEHGHMLM_02160 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEHGHMLM_02161 0.0 yubD - - P - - - Major Facilitator Superfamily
KEHGHMLM_02162 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
KEHGHMLM_02164 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KEHGHMLM_02165 1.73e-252 yubA - - S - - - transporter activity
KEHGHMLM_02166 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KEHGHMLM_02167 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
KEHGHMLM_02168 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
KEHGHMLM_02169 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KEHGHMLM_02170 2.87e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KEHGHMLM_02171 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
KEHGHMLM_02173 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_02174 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_02175 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_02176 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_02177 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
KEHGHMLM_02178 1.44e-47 - - - - - - - -
KEHGHMLM_02179 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
KEHGHMLM_02180 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KEHGHMLM_02181 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
KEHGHMLM_02182 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
KEHGHMLM_02183 2.24e-50 - - - - - - - -
KEHGHMLM_02184 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
KEHGHMLM_02185 2.06e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
KEHGHMLM_02186 1.72e-94 yugN - - S - - - YugN-like family
KEHGHMLM_02188 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KEHGHMLM_02189 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
KEHGHMLM_02190 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
KEHGHMLM_02191 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
KEHGHMLM_02192 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KEHGHMLM_02193 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
KEHGHMLM_02194 6.74e-112 alaR - - K - - - Transcriptional regulator
KEHGHMLM_02195 9.89e-201 yugF - - I - - - Hydrolase
KEHGHMLM_02196 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
KEHGHMLM_02197 1.11e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KEHGHMLM_02198 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_02199 4.84e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
KEHGHMLM_02200 3.46e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
KEHGHMLM_02202 2.97e-240 yuxJ - - EGP - - - Major facilitator superfamily
KEHGHMLM_02203 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
KEHGHMLM_02204 1.92e-97 yuxK - - S - - - protein conserved in bacteria
KEHGHMLM_02205 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
KEHGHMLM_02206 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KEHGHMLM_02207 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KEHGHMLM_02208 1.49e-252 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KEHGHMLM_02209 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02210 9.08e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KEHGHMLM_02211 4.9e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KEHGHMLM_02212 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
KEHGHMLM_02213 1.42e-21 - - - - - - - -
KEHGHMLM_02214 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KEHGHMLM_02215 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEHGHMLM_02216 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEHGHMLM_02217 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEHGHMLM_02218 2.47e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEHGHMLM_02219 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KEHGHMLM_02220 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
KEHGHMLM_02221 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
KEHGHMLM_02222 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_02223 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_02225 1.16e-181 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
KEHGHMLM_02226 6.29e-10 - - - S - - - DegQ (SacQ) family
KEHGHMLM_02227 8.73e-09 yuzC - - - - - - -
KEHGHMLM_02228 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
KEHGHMLM_02229 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KEHGHMLM_02230 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
KEHGHMLM_02231 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
KEHGHMLM_02232 1.63e-52 yueH - - S - - - YueH-like protein
KEHGHMLM_02233 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
KEHGHMLM_02234 2.73e-244 yueF - - S - - - transporter activity
KEHGHMLM_02235 1.68e-85 - - - S - - - Protein of unknown function (DUF2283)
KEHGHMLM_02236 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
KEHGHMLM_02237 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
KEHGHMLM_02238 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_02239 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
KEHGHMLM_02240 0.0 yueB - - S - - - type VII secretion protein EsaA
KEHGHMLM_02241 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KEHGHMLM_02242 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
KEHGHMLM_02243 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
KEHGHMLM_02244 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
KEHGHMLM_02245 2.96e-292 yukF - - QT - - - Transcriptional regulator
KEHGHMLM_02246 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KEHGHMLM_02247 4.88e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
KEHGHMLM_02248 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
KEHGHMLM_02249 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_02250 1.1e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
KEHGHMLM_02251 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
KEHGHMLM_02252 3.48e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
KEHGHMLM_02253 4.1e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_02254 2.46e-210 eSD - - S ko:K07017 - ko00000 Putative esterase
KEHGHMLM_02255 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
KEHGHMLM_02256 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
KEHGHMLM_02257 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
KEHGHMLM_02258 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KEHGHMLM_02259 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
KEHGHMLM_02260 5.66e-150 yuiC - - S - - - protein conserved in bacteria
KEHGHMLM_02261 9.78e-47 yuiB - - S - - - Putative membrane protein
KEHGHMLM_02262 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KEHGHMLM_02263 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
KEHGHMLM_02265 6.68e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KEHGHMLM_02266 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
KEHGHMLM_02267 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_02268 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
KEHGHMLM_02269 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KEHGHMLM_02270 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEHGHMLM_02271 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
KEHGHMLM_02272 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KEHGHMLM_02273 1.1e-73 yuzD - - S - - - protein conserved in bacteria
KEHGHMLM_02274 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
KEHGHMLM_02275 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
KEHGHMLM_02276 8.58e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KEHGHMLM_02277 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KEHGHMLM_02278 3.36e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KEHGHMLM_02279 1.55e-253 yutH - - S - - - Spore coat protein
KEHGHMLM_02280 3.21e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
KEHGHMLM_02281 2.49e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KEHGHMLM_02282 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
KEHGHMLM_02283 3.2e-63 yutD - - S - - - protein conserved in bacteria
KEHGHMLM_02284 5.47e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KEHGHMLM_02285 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KEHGHMLM_02286 3.11e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
KEHGHMLM_02287 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
KEHGHMLM_02288 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
KEHGHMLM_02289 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KEHGHMLM_02290 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
KEHGHMLM_02291 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
KEHGHMLM_02292 3.06e-79 yunG - - - - - - -
KEHGHMLM_02293 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KEHGHMLM_02294 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
KEHGHMLM_02295 4.36e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
KEHGHMLM_02296 1.65e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
KEHGHMLM_02297 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KEHGHMLM_02298 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KEHGHMLM_02299 1.46e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KEHGHMLM_02300 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KEHGHMLM_02301 4.27e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KEHGHMLM_02302 1.03e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
KEHGHMLM_02303 2.09e-242 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KEHGHMLM_02305 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KEHGHMLM_02306 1.38e-293 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KEHGHMLM_02307 6.53e-218 bsn - - L - - - Ribonuclease
KEHGHMLM_02308 6.95e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_02309 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KEHGHMLM_02310 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
KEHGHMLM_02311 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
KEHGHMLM_02312 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_02313 1.17e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
KEHGHMLM_02314 1.29e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KEHGHMLM_02315 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
KEHGHMLM_02316 4.87e-260 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
KEHGHMLM_02318 4.76e-56 - - - - - - - -
KEHGHMLM_02319 6.91e-84 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_02320 1.03e-55 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KEHGHMLM_02321 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
KEHGHMLM_02322 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
KEHGHMLM_02323 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KEHGHMLM_02324 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KEHGHMLM_02325 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KEHGHMLM_02326 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KEHGHMLM_02327 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KEHGHMLM_02328 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
KEHGHMLM_02329 1.24e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KEHGHMLM_02330 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
KEHGHMLM_02331 2e-73 yusE - - CO - - - Thioredoxin
KEHGHMLM_02332 2.18e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
KEHGHMLM_02333 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
KEHGHMLM_02334 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KEHGHMLM_02335 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KEHGHMLM_02336 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
KEHGHMLM_02337 3.84e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
KEHGHMLM_02338 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
KEHGHMLM_02339 2.86e-14 - - - S - - - YuzL-like protein
KEHGHMLM_02340 4.91e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KEHGHMLM_02341 2.23e-54 - - - - - - - -
KEHGHMLM_02342 8.66e-70 yusN - - M - - - Coat F domain
KEHGHMLM_02343 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
KEHGHMLM_02344 0.0 yusP - - P - - - Major facilitator superfamily
KEHGHMLM_02345 1.7e-84 yusQ - - S - - - Tautomerase enzyme
KEHGHMLM_02346 4.07e-137 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_02347 1.98e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
KEHGHMLM_02348 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
KEHGHMLM_02349 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KEHGHMLM_02350 3.48e-88 - - - S - - - YusW-like protein
KEHGHMLM_02351 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
KEHGHMLM_02352 1.5e-194 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_02353 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
KEHGHMLM_02354 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEHGHMLM_02355 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_02356 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_02357 3.06e-204 yuxN - - K - - - Transcriptional regulator
KEHGHMLM_02358 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KEHGHMLM_02359 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
KEHGHMLM_02360 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KEHGHMLM_02361 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KEHGHMLM_02362 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
KEHGHMLM_02363 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_02364 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_02365 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
KEHGHMLM_02366 3.11e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KEHGHMLM_02367 8.16e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KEHGHMLM_02368 4.34e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
KEHGHMLM_02369 3.76e-287 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_02370 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
KEHGHMLM_02371 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KEHGHMLM_02372 1.49e-233 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_02373 2.01e-216 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KEHGHMLM_02374 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_02375 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
KEHGHMLM_02376 0.0 yvrG - - T - - - Histidine kinase
KEHGHMLM_02377 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_02378 5.07e-32 - - - - - - - -
KEHGHMLM_02379 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
KEHGHMLM_02380 3.46e-26 - - - S - - - YvrJ protein family
KEHGHMLM_02381 9.23e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
KEHGHMLM_02382 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
KEHGHMLM_02383 6.32e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
KEHGHMLM_02384 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02385 1.15e-227 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
KEHGHMLM_02386 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KEHGHMLM_02387 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_02388 6e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_02389 1.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KEHGHMLM_02390 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KEHGHMLM_02391 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
KEHGHMLM_02392 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KEHGHMLM_02393 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
KEHGHMLM_02394 1.03e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
KEHGHMLM_02395 1.8e-176 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
KEHGHMLM_02396 4.79e-151 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
KEHGHMLM_02397 2.63e-202 yvgN - - S - - - reductase
KEHGHMLM_02398 1.61e-112 yvgO - - - - - - -
KEHGHMLM_02399 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
KEHGHMLM_02400 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KEHGHMLM_02401 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KEHGHMLM_02402 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KEHGHMLM_02403 3.88e-140 yvgT - - S - - - membrane
KEHGHMLM_02404 2.83e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
KEHGHMLM_02405 3.45e-137 bdbD - - O - - - Thioredoxin
KEHGHMLM_02406 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
KEHGHMLM_02407 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KEHGHMLM_02408 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
KEHGHMLM_02409 3.99e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
KEHGHMLM_02410 5.71e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KEHGHMLM_02411 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KEHGHMLM_02412 1.43e-284 - - - S - - - Fusaric acid resistance protein-like
KEHGHMLM_02413 3.77e-117 - - - S - - - Fusaric acid resistance protein-like
KEHGHMLM_02414 2.07e-30 yvaD - - S - - - Family of unknown function (DUF5360)
KEHGHMLM_02415 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KEHGHMLM_02416 2.01e-127 - - - K - - - Bacterial regulatory proteins, tetR family
KEHGHMLM_02417 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_02419 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KEHGHMLM_02420 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KEHGHMLM_02421 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
KEHGHMLM_02422 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KEHGHMLM_02423 3.32e-193 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
KEHGHMLM_02424 3.44e-48 yvzC - - K - - - transcriptional
KEHGHMLM_02425 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
KEHGHMLM_02426 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KEHGHMLM_02427 3.85e-72 yvaP - - K - - - transcriptional
KEHGHMLM_02428 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_02429 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KEHGHMLM_02430 1.95e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KEHGHMLM_02431 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KEHGHMLM_02432 4.95e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KEHGHMLM_02433 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KEHGHMLM_02434 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KEHGHMLM_02435 1.74e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KEHGHMLM_02436 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
KEHGHMLM_02437 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KEHGHMLM_02438 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
KEHGHMLM_02439 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KEHGHMLM_02440 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
KEHGHMLM_02441 1.61e-156 yvbI - - M - - - Membrane
KEHGHMLM_02442 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KEHGHMLM_02443 6.87e-106 yvbK - - K - - - acetyltransferase
KEHGHMLM_02444 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KEHGHMLM_02445 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
KEHGHMLM_02446 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEHGHMLM_02447 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KEHGHMLM_02448 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEHGHMLM_02449 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KEHGHMLM_02450 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KEHGHMLM_02451 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
KEHGHMLM_02452 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEHGHMLM_02454 5.49e-205 yvbU - - K - - - Transcriptional regulator
KEHGHMLM_02455 3.93e-198 yvbV - - EG - - - EamA-like transporter family
KEHGHMLM_02456 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_02457 3e-249 - - - S - - - Glycosyl hydrolase
KEHGHMLM_02458 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KEHGHMLM_02459 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KEHGHMLM_02460 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KEHGHMLM_02461 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_02462 8.34e-256 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_02463 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KEHGHMLM_02464 3.85e-205 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
KEHGHMLM_02465 1.71e-199 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
KEHGHMLM_02466 1.55e-258 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
KEHGHMLM_02467 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
KEHGHMLM_02468 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
KEHGHMLM_02469 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KEHGHMLM_02470 1.24e-299 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KEHGHMLM_02471 7.78e-286 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KEHGHMLM_02472 1.51e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_02473 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
KEHGHMLM_02474 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KEHGHMLM_02475 3.9e-303 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KEHGHMLM_02476 5.69e-44 yvfG - - S - - - YvfG protein
KEHGHMLM_02477 5.31e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
KEHGHMLM_02478 2.05e-276 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KEHGHMLM_02479 1.01e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KEHGHMLM_02480 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KEHGHMLM_02481 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEHGHMLM_02482 8.59e-249 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KEHGHMLM_02483 1.91e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
KEHGHMLM_02484 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KEHGHMLM_02485 1.03e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
KEHGHMLM_02486 2.56e-272 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KEHGHMLM_02487 5.09e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
KEHGHMLM_02488 1.15e-283 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
KEHGHMLM_02489 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
KEHGHMLM_02490 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KEHGHMLM_02491 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
KEHGHMLM_02492 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
KEHGHMLM_02493 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
KEHGHMLM_02494 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KEHGHMLM_02495 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
KEHGHMLM_02496 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KEHGHMLM_02497 0.0 pbpE - - V - - - Beta-lactamase
KEHGHMLM_02498 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
KEHGHMLM_02499 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KEHGHMLM_02500 0.0 ybeC - - E - - - amino acid
KEHGHMLM_02501 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
KEHGHMLM_02502 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
KEHGHMLM_02503 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
KEHGHMLM_02504 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
KEHGHMLM_02505 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
KEHGHMLM_02506 9.45e-234 - - - S - - - Patatin-like phospholipase
KEHGHMLM_02508 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KEHGHMLM_02509 2.91e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KEHGHMLM_02510 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KEHGHMLM_02511 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
KEHGHMLM_02512 1.23e-196 malA - - S - - - Protein of unknown function (DUF1189)
KEHGHMLM_02513 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KEHGHMLM_02514 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
KEHGHMLM_02515 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
KEHGHMLM_02516 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
KEHGHMLM_02517 1.54e-221 yvdE - - K - - - Transcriptional regulator
KEHGHMLM_02518 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KEHGHMLM_02519 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
KEHGHMLM_02520 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KEHGHMLM_02521 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KEHGHMLM_02522 2.32e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEHGHMLM_02523 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KEHGHMLM_02524 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02525 2.38e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
KEHGHMLM_02526 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_02527 1.32e-43 - - - - - - - -
KEHGHMLM_02528 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
KEHGHMLM_02529 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
KEHGHMLM_02530 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KEHGHMLM_02531 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KEHGHMLM_02532 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KEHGHMLM_02533 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KEHGHMLM_02534 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KEHGHMLM_02535 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
KEHGHMLM_02536 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
KEHGHMLM_02537 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KEHGHMLM_02539 0.0 - - - - - - - -
KEHGHMLM_02540 5.25e-111 - - - - - - - -
KEHGHMLM_02541 8.75e-91 - - - - - - - -
KEHGHMLM_02542 5.91e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
KEHGHMLM_02543 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KEHGHMLM_02544 3.95e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KEHGHMLM_02545 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KEHGHMLM_02546 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KEHGHMLM_02547 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KEHGHMLM_02548 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KEHGHMLM_02549 6.64e-279 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KEHGHMLM_02550 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
KEHGHMLM_02551 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
KEHGHMLM_02552 1.69e-108 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
KEHGHMLM_02553 1.76e-152 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KEHGHMLM_02554 3.05e-210 yvoD - - P - - - COG0370 Fe2 transport system protein B
KEHGHMLM_02555 1.29e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KEHGHMLM_02556 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KEHGHMLM_02557 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KEHGHMLM_02558 1.43e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEHGHMLM_02559 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
KEHGHMLM_02560 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
KEHGHMLM_02561 5.44e-109 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_02562 2.19e-291 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
KEHGHMLM_02563 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KEHGHMLM_02564 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_02565 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
KEHGHMLM_02566 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
KEHGHMLM_02567 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KEHGHMLM_02568 5.8e-221 yvlB - - S - - - Putative adhesin
KEHGHMLM_02569 8.09e-65 yvlA - - - - - - -
KEHGHMLM_02570 2.25e-45 yvkN - - - - - - -
KEHGHMLM_02571 1.23e-146 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KEHGHMLM_02572 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KEHGHMLM_02573 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KEHGHMLM_02574 2.54e-42 csbA - - S - - - protein conserved in bacteria
KEHGHMLM_02575 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
KEHGHMLM_02576 1.43e-131 yvkB - - K - - - Transcriptional regulator
KEHGHMLM_02577 2.13e-295 yvkA - - P - - - -transporter
KEHGHMLM_02578 6.4e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEHGHMLM_02579 1.38e-73 swrA - - S - - - Swarming motility protein
KEHGHMLM_02580 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KEHGHMLM_02581 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KEHGHMLM_02582 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KEHGHMLM_02583 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
KEHGHMLM_02584 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KEHGHMLM_02585 8.14e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KEHGHMLM_02586 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KEHGHMLM_02587 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KEHGHMLM_02588 3.72e-87 - - - - - - - -
KEHGHMLM_02589 9.58e-08 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
KEHGHMLM_02590 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
KEHGHMLM_02591 1.27e-312 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KEHGHMLM_02592 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
KEHGHMLM_02593 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KEHGHMLM_02594 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KEHGHMLM_02595 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KEHGHMLM_02596 1.7e-92 yviE - - - - - - -
KEHGHMLM_02597 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
KEHGHMLM_02598 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
KEHGHMLM_02599 1.43e-101 yvyG - - NOU - - - FlgN protein
KEHGHMLM_02600 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
KEHGHMLM_02601 7.48e-96 yvyF - - S - - - flagellar protein
KEHGHMLM_02602 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
KEHGHMLM_02603 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
KEHGHMLM_02604 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KEHGHMLM_02605 2.15e-199 degV - - S - - - protein conserved in bacteria
KEHGHMLM_02606 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_02607 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KEHGHMLM_02608 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
KEHGHMLM_02609 4.43e-222 yvhJ - - K - - - Transcriptional regulator
KEHGHMLM_02610 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KEHGHMLM_02611 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
KEHGHMLM_02612 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
KEHGHMLM_02613 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
KEHGHMLM_02614 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
KEHGHMLM_02615 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEHGHMLM_02616 4.66e-278 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
KEHGHMLM_02617 3.98e-313 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEHGHMLM_02618 3.01e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KEHGHMLM_02619 1.27e-108 - - - M - - - Glycosyltransferase like family 2
KEHGHMLM_02620 2.61e-264 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KEHGHMLM_02621 0.0 lytB - - D - - - Stage II sporulation protein
KEHGHMLM_02622 9.07e-16 - - - - - - - -
KEHGHMLM_02623 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KEHGHMLM_02624 1.74e-273 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KEHGHMLM_02625 1.48e-103 - - - M - - - Glycosyltransferase like family 2
KEHGHMLM_02626 3.43e-118 - - - M - - - Glycosyl transferases group 1
KEHGHMLM_02628 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KEHGHMLM_02629 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KEHGHMLM_02630 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KEHGHMLM_02631 3.08e-181 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEHGHMLM_02632 6.73e-165 - - - M - - - Glycosyltransferase like family 2
KEHGHMLM_02633 2.93e-102 - - - - - - - -
KEHGHMLM_02634 2.57e-135 - - - M - - - Glycosyltransferase like family 2
KEHGHMLM_02635 6.32e-167 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEHGHMLM_02636 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
KEHGHMLM_02637 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KEHGHMLM_02638 3.84e-117 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KEHGHMLM_02639 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KEHGHMLM_02640 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KEHGHMLM_02641 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEHGHMLM_02642 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KEHGHMLM_02643 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEHGHMLM_02644 2.62e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KEHGHMLM_02645 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
KEHGHMLM_02646 1.14e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
KEHGHMLM_02647 1.33e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
KEHGHMLM_02648 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KEHGHMLM_02649 2.11e-222 ywtF_2 - - K - - - Transcriptional regulator
KEHGHMLM_02650 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KEHGHMLM_02651 2.76e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KEHGHMLM_02652 4.62e-29 ywtC - - - - - - -
KEHGHMLM_02653 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KEHGHMLM_02654 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
KEHGHMLM_02655 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
KEHGHMLM_02656 1.09e-226 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
KEHGHMLM_02657 2.62e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEHGHMLM_02658 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KEHGHMLM_02659 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KEHGHMLM_02660 1.93e-202 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KEHGHMLM_02661 1.28e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
KEHGHMLM_02662 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
KEHGHMLM_02663 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
KEHGHMLM_02664 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
KEHGHMLM_02665 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KEHGHMLM_02666 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KEHGHMLM_02667 3.36e-218 alsR - - K - - - LysR substrate binding domain
KEHGHMLM_02668 2.79e-280 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KEHGHMLM_02669 4.33e-162 ywrJ - - - - - - -
KEHGHMLM_02670 1.43e-182 cotB - - - ko:K06325 - ko00000 -
KEHGHMLM_02671 9.22e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
KEHGHMLM_02672 2.17e-16 - - - - - - - -
KEHGHMLM_02673 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KEHGHMLM_02674 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
KEHGHMLM_02675 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
KEHGHMLM_02676 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KEHGHMLM_02677 1.85e-131 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
KEHGHMLM_02678 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
KEHGHMLM_02680 1.5e-129 ywqN - - S - - - NAD(P)H-dependent
KEHGHMLM_02681 4.73e-209 - - - K - - - Transcriptional regulator
KEHGHMLM_02682 9.14e-152 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KEHGHMLM_02684 2.32e-99 ywqJ - - S - - - Pre-toxin TG
KEHGHMLM_02685 1.3e-23 - - - - - - - -
KEHGHMLM_02686 1.77e-26 - - - - - - - -
KEHGHMLM_02687 5.16e-264 - - - L - - - nucleic acid phosphodiester bond hydrolysis
KEHGHMLM_02688 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
KEHGHMLM_02690 4.7e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
KEHGHMLM_02691 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KEHGHMLM_02692 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
KEHGHMLM_02693 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
KEHGHMLM_02694 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
KEHGHMLM_02695 3.6e-25 - - - - - - - -
KEHGHMLM_02696 0.0 ywqB - - S - - - SWIM zinc finger
KEHGHMLM_02697 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
KEHGHMLM_02698 1.07e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KEHGHMLM_02699 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KEHGHMLM_02700 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KEHGHMLM_02701 3.04e-87 ywpG - - - - - - -
KEHGHMLM_02702 8.81e-89 ywpF - - S - - - YwpF-like protein
KEHGHMLM_02703 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KEHGHMLM_02704 2.51e-18 - - - M - - - cell wall anchor domain
KEHGHMLM_02705 1.28e-66 ywpD - - T - - - Histidine kinase
KEHGHMLM_02706 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KEHGHMLM_02707 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KEHGHMLM_02708 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
KEHGHMLM_02709 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KEHGHMLM_02710 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
KEHGHMLM_02711 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
KEHGHMLM_02712 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
KEHGHMLM_02713 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
KEHGHMLM_02714 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_02715 2.4e-311 ywoF - - P - - - Right handed beta helix region
KEHGHMLM_02716 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
KEHGHMLM_02717 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
KEHGHMLM_02718 1.04e-133 yjgF - - Q - - - Isochorismatase family
KEHGHMLM_02719 5.04e-101 - - - - - - - -
KEHGHMLM_02720 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
KEHGHMLM_02721 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
KEHGHMLM_02722 3.48e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
KEHGHMLM_02723 5.24e-92 ywnJ - - S - - - VanZ like family
KEHGHMLM_02724 1.3e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
KEHGHMLM_02725 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
KEHGHMLM_02726 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
KEHGHMLM_02727 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
KEHGHMLM_02728 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEHGHMLM_02729 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
KEHGHMLM_02730 3.55e-77 ywnC - - S - - - Family of unknown function (DUF5362)
KEHGHMLM_02731 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
KEHGHMLM_02732 2.65e-84 ywnA - - K - - - Transcriptional regulator
KEHGHMLM_02733 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KEHGHMLM_02734 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
KEHGHMLM_02735 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KEHGHMLM_02736 7.49e-20 csbD - - K - - - CsbD-like
KEHGHMLM_02737 1.21e-109 ywmF - - S - - - Peptidase M50
KEHGHMLM_02738 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KEHGHMLM_02739 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KEHGHMLM_02740 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KEHGHMLM_02742 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KEHGHMLM_02743 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KEHGHMLM_02744 2.8e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
KEHGHMLM_02745 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEHGHMLM_02746 1.14e-172 ywmB - - S - - - TATA-box binding
KEHGHMLM_02747 4.54e-45 ywzB - - S - - - membrane
KEHGHMLM_02748 1.69e-112 ywmA - - - - - - -
KEHGHMLM_02749 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KEHGHMLM_02750 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KEHGHMLM_02751 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KEHGHMLM_02752 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KEHGHMLM_02753 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEHGHMLM_02754 1.24e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KEHGHMLM_02755 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEHGHMLM_02756 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KEHGHMLM_02757 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
KEHGHMLM_02758 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KEHGHMLM_02759 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KEHGHMLM_02760 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
KEHGHMLM_02761 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
KEHGHMLM_02762 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEHGHMLM_02763 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
KEHGHMLM_02764 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KEHGHMLM_02765 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
KEHGHMLM_02766 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
KEHGHMLM_02767 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
KEHGHMLM_02769 7.78e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KEHGHMLM_02770 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KEHGHMLM_02771 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_02772 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KEHGHMLM_02773 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KEHGHMLM_02774 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
KEHGHMLM_02775 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KEHGHMLM_02776 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KEHGHMLM_02777 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KEHGHMLM_02778 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
KEHGHMLM_02779 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEHGHMLM_02780 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KEHGHMLM_02781 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
KEHGHMLM_02782 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
KEHGHMLM_02783 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
KEHGHMLM_02784 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KEHGHMLM_02785 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KEHGHMLM_02786 3.48e-268 acdA - - I - - - acyl-CoA dehydrogenase
KEHGHMLM_02787 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
KEHGHMLM_02788 9.57e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KEHGHMLM_02789 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KEHGHMLM_02790 1.32e-57 ywjC - - - - - - -
KEHGHMLM_02791 1.35e-124 ywjB - - H - - - RibD C-terminal domain
KEHGHMLM_02792 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KEHGHMLM_02793 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEHGHMLM_02794 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
KEHGHMLM_02795 1.95e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
KEHGHMLM_02796 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
KEHGHMLM_02797 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEHGHMLM_02798 7.13e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
KEHGHMLM_02799 1.84e-179 ywiC - - S - - - YwiC-like protein
KEHGHMLM_02800 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
KEHGHMLM_02801 1.7e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KEHGHMLM_02802 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KEHGHMLM_02803 4.64e-96 ywiB - - S - - - protein conserved in bacteria
KEHGHMLM_02804 3.71e-12 - - - S - - - Bacteriocin subtilosin A
KEHGHMLM_02805 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
KEHGHMLM_02807 3.03e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KEHGHMLM_02808 2.41e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
KEHGHMLM_02809 8.09e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
KEHGHMLM_02810 3.9e-316 - - - L - - - Peptidase, M16
KEHGHMLM_02812 0.0 ywhL - - CO - - - amine dehydrogenase activity
KEHGHMLM_02813 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
KEHGHMLM_02814 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KEHGHMLM_02817 1.52e-14 - - - S - - - ABC-2 family transporter protein
KEHGHMLM_02820 7.42e-77 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KEHGHMLM_02822 1.42e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KEHGHMLM_02823 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KEHGHMLM_02824 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KEHGHMLM_02825 7.83e-123 ywhD - - S - - - YwhD family
KEHGHMLM_02826 3.29e-154 ywhC - - S - - - Peptidase family M50
KEHGHMLM_02827 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
KEHGHMLM_02828 1.45e-93 ywhA - - K - - - Transcriptional regulator
KEHGHMLM_02829 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEHGHMLM_02831 6.75e-304 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
KEHGHMLM_02832 3.15e-103 yffB - - K - - - Transcriptional regulator
KEHGHMLM_02833 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
KEHGHMLM_02834 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
KEHGHMLM_02835 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
KEHGHMLM_02836 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
KEHGHMLM_02837 3.7e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
KEHGHMLM_02838 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KEHGHMLM_02839 5.53e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_02840 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
KEHGHMLM_02841 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
KEHGHMLM_02842 4.1e-177 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
KEHGHMLM_02843 4.46e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KEHGHMLM_02844 9.19e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
KEHGHMLM_02845 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KEHGHMLM_02846 4.47e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_02847 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KEHGHMLM_02848 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KEHGHMLM_02849 6.3e-274 ywfA - - EGP - - - -transporter
KEHGHMLM_02850 8.84e-317 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KEHGHMLM_02851 0.0 rocB - - E - - - arginine degradation protein
KEHGHMLM_02852 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KEHGHMLM_02853 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KEHGHMLM_02854 3.7e-101 - - - - - - - -
KEHGHMLM_02855 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
KEHGHMLM_02856 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KEHGHMLM_02857 1.83e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KEHGHMLM_02858 2.14e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KEHGHMLM_02859 2.24e-237 spsG - - M - - - Spore Coat
KEHGHMLM_02860 1.18e-162 spsF - - M ko:K07257 - ko00000 Spore Coat
KEHGHMLM_02861 1.31e-269 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
KEHGHMLM_02862 1.72e-209 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
KEHGHMLM_02863 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
KEHGHMLM_02864 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
KEHGHMLM_02865 8.08e-187 spsA - - M - - - Spore Coat
KEHGHMLM_02866 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KEHGHMLM_02867 1.59e-78 ywdK - - S - - - small membrane protein
KEHGHMLM_02868 1.86e-303 ywdJ - - F - - - Xanthine uracil
KEHGHMLM_02869 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
KEHGHMLM_02870 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KEHGHMLM_02871 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KEHGHMLM_02872 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
KEHGHMLM_02874 8.74e-146 ywdD - - - - - - -
KEHGHMLM_02875 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
KEHGHMLM_02876 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KEHGHMLM_02877 6.19e-39 ywdA - - - - - - -
KEHGHMLM_02878 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KEHGHMLM_02879 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_02880 1.61e-177 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
KEHGHMLM_02881 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KEHGHMLM_02883 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KEHGHMLM_02884 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEHGHMLM_02885 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
KEHGHMLM_02886 5.14e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KEHGHMLM_02887 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
KEHGHMLM_02888 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KEHGHMLM_02889 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
KEHGHMLM_02890 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KEHGHMLM_02891 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KEHGHMLM_02892 5.11e-49 ydaS - - S - - - membrane
KEHGHMLM_02893 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KEHGHMLM_02894 2.17e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KEHGHMLM_02895 3.88e-76 gtcA - - S - - - GtrA-like protein
KEHGHMLM_02896 3.42e-158 ywcC - - K - - - transcriptional regulator
KEHGHMLM_02898 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
KEHGHMLM_02899 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEHGHMLM_02900 4.43e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
KEHGHMLM_02901 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
KEHGHMLM_02902 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
KEHGHMLM_02903 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
KEHGHMLM_02904 2.47e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KEHGHMLM_02905 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KEHGHMLM_02906 3.73e-203 ywbI - - K - - - Transcriptional regulator
KEHGHMLM_02907 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KEHGHMLM_02908 7e-143 ywbG - - M - - - effector of murein hydrolase
KEHGHMLM_02909 4.31e-277 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
KEHGHMLM_02910 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
KEHGHMLM_02911 8.07e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KEHGHMLM_02912 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
KEHGHMLM_02913 1.5e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEHGHMLM_02914 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KEHGHMLM_02915 2.79e-310 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_02916 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KEHGHMLM_02917 4.41e-215 gspA - - M - - - General stress
KEHGHMLM_02918 4.08e-157 ywaF - - S - - - Integral membrane protein
KEHGHMLM_02919 3.57e-114 ywaE - - K - - - Transcriptional regulator
KEHGHMLM_02920 2.9e-293 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEHGHMLM_02921 3.65e-316 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
KEHGHMLM_02922 2.67e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
KEHGHMLM_02923 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KEHGHMLM_02924 3.96e-165 - - - EGP - - - Permeases of the major facilitator superfamily
KEHGHMLM_02925 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
KEHGHMLM_02926 4.89e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KEHGHMLM_02927 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
KEHGHMLM_02928 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_02929 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
KEHGHMLM_02930 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_02931 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KEHGHMLM_02932 4.83e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_02933 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KEHGHMLM_02934 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KEHGHMLM_02935 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_02936 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEHGHMLM_02937 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
KEHGHMLM_02938 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KEHGHMLM_02939 8.94e-28 yxzF - - - - - - -
KEHGHMLM_02940 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KEHGHMLM_02941 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KEHGHMLM_02942 1.05e-269 yxlH - - EGP - - - Major Facilitator Superfamily
KEHGHMLM_02943 1.23e-113 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEHGHMLM_02944 1.36e-40 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEHGHMLM_02945 1.65e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_02946 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
KEHGHMLM_02947 1.75e-43 - - - - - - - -
KEHGHMLM_02948 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
KEHGHMLM_02949 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_02950 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
KEHGHMLM_02951 7.23e-200 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KEHGHMLM_02952 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
KEHGHMLM_02953 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
KEHGHMLM_02954 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
KEHGHMLM_02955 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
KEHGHMLM_02956 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
KEHGHMLM_02957 0.0 - - - O - - - Peptidase family M48
KEHGHMLM_02959 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
KEHGHMLM_02960 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KEHGHMLM_02961 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
KEHGHMLM_02962 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEHGHMLM_02963 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KEHGHMLM_02964 1.95e-99 yxkC - - S - - - Domain of unknown function (DUF4352)
KEHGHMLM_02965 6.06e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KEHGHMLM_02966 9.35e-101 - - - S - - - Protein of unknown function (DUF1453)
KEHGHMLM_02967 3.23e-257 - - - T - - - Signal transduction histidine kinase
KEHGHMLM_02968 1.1e-147 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
KEHGHMLM_02969 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KEHGHMLM_02972 2.88e-111 yxjI - - S - - - LURP-one-related
KEHGHMLM_02973 8.66e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KEHGHMLM_02974 2.57e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KEHGHMLM_02975 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KEHGHMLM_02976 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KEHGHMLM_02977 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KEHGHMLM_02978 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
KEHGHMLM_02979 4.19e-202 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
KEHGHMLM_02980 1.21e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEHGHMLM_02981 1.15e-130 - - - T - - - Domain of unknown function (DUF4163)
KEHGHMLM_02982 2.28e-63 yxiS - - - - - - -
KEHGHMLM_02983 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
KEHGHMLM_02984 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KEHGHMLM_02985 1.77e-183 bglS - - M - - - licheninase activity
KEHGHMLM_02986 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KEHGHMLM_02987 1.07e-142 - - - - - - - -
KEHGHMLM_02988 2.99e-289 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
KEHGHMLM_02989 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KEHGHMLM_02990 2.65e-269 - - - E - - - GDSL-like Lipase/Acylhydrolase
KEHGHMLM_02993 6.23e-62 yxiJ - - S - - - YxiJ-like protein
KEHGHMLM_02994 1.74e-121 yxiI - - S - - - Protein of unknown function (DUF2716)
KEHGHMLM_02995 6.18e-176 - - - - - - - -
KEHGHMLM_02996 8.76e-99 yxiG - - - - - - -
KEHGHMLM_02997 1.12e-82 - - - - - - - -
KEHGHMLM_02998 3.69e-111 - - - - - - - -
KEHGHMLM_02999 1.09e-94 yxxG - - - - - - -
KEHGHMLM_03000 0.0 wapA - - M - - - COG3209 Rhs family protein
KEHGHMLM_03001 4.67e-207 yxxF - - EG - - - EamA-like transporter family
KEHGHMLM_03002 9.93e-94 yxiE - - T - - - Belongs to the universal stress protein A family
KEHGHMLM_03003 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KEHGHMLM_03004 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03005 8.25e-69 - - - - - - - -
KEHGHMLM_03006 2.12e-276 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
KEHGHMLM_03007 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
KEHGHMLM_03008 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
KEHGHMLM_03009 0.0 - - - L - - - HKD family nuclease
KEHGHMLM_03011 3.7e-77 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KEHGHMLM_03012 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
KEHGHMLM_03014 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KEHGHMLM_03015 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
KEHGHMLM_03016 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KEHGHMLM_03017 5.04e-296 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
KEHGHMLM_03018 3.98e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KEHGHMLM_03019 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KEHGHMLM_03020 4.02e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
KEHGHMLM_03021 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KEHGHMLM_03022 4.8e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KEHGHMLM_03023 2.02e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KEHGHMLM_03024 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
KEHGHMLM_03025 3.01e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
KEHGHMLM_03026 2.06e-314 yxeQ - - S - - - MmgE/PrpD family
KEHGHMLM_03027 2.77e-270 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
KEHGHMLM_03028 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_03029 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KEHGHMLM_03030 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KEHGHMLM_03031 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEHGHMLM_03032 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEHGHMLM_03033 2.92e-232 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KEHGHMLM_03034 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
KEHGHMLM_03037 7.32e-42 yxeE - - - - - - -
KEHGHMLM_03038 7.57e-28 yxeD - - - - - - -
KEHGHMLM_03039 9.65e-91 - - - - - - - -
KEHGHMLM_03040 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KEHGHMLM_03041 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
KEHGHMLM_03042 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KEHGHMLM_03043 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_03044 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_03045 3.27e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_03046 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KEHGHMLM_03047 3.26e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KEHGHMLM_03048 3.09e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
KEHGHMLM_03049 1.05e-249 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KEHGHMLM_03050 4.19e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
KEHGHMLM_03051 7.09e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KEHGHMLM_03052 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KEHGHMLM_03053 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KEHGHMLM_03054 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KEHGHMLM_03055 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEHGHMLM_03056 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KEHGHMLM_03057 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KEHGHMLM_03059 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
KEHGHMLM_03060 4.16e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KEHGHMLM_03061 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
KEHGHMLM_03063 2.92e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KEHGHMLM_03064 1.47e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
KEHGHMLM_03065 7.19e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KEHGHMLM_03066 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
KEHGHMLM_03067 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
KEHGHMLM_03068 7.46e-177 yxbB - - Q - - - Met-10+ like-protein
KEHGHMLM_03069 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
KEHGHMLM_03070 8.99e-114 yxnB - - - - - - -
KEHGHMLM_03071 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KEHGHMLM_03072 1.8e-271 yxaM - - U - - - MFS_1 like family
KEHGHMLM_03073 7.49e-137 yxaL - - S - - - PQQ-like domain
KEHGHMLM_03074 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
KEHGHMLM_03075 1.64e-98 yxaI - - S - - - membrane protein domain
KEHGHMLM_03076 4.77e-289 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
KEHGHMLM_03077 1.31e-244 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
KEHGHMLM_03078 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KEHGHMLM_03079 8.67e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KEHGHMLM_03080 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_03081 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
KEHGHMLM_03082 1.27e-152 yxaC - - M - - - effector of murein hydrolase
KEHGHMLM_03083 1.04e-244 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
KEHGHMLM_03084 6.98e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KEHGHMLM_03085 2.1e-162 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
KEHGHMLM_03086 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KEHGHMLM_03087 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
KEHGHMLM_03088 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEHGHMLM_03089 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
KEHGHMLM_03090 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
KEHGHMLM_03091 2.24e-237 - - - S - - - Polysaccharide pyruvyl transferase
KEHGHMLM_03092 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KEHGHMLM_03093 8.38e-44 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03094 1.23e-162 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_03095 2.4e-23 - - - - - - - -
KEHGHMLM_03096 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
KEHGHMLM_03097 0.0 - - - L - - - AAA domain
KEHGHMLM_03098 6.93e-310 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KEHGHMLM_03099 3.64e-56 - - - S - - - MazG-like family
KEHGHMLM_03100 1.36e-141 - - - S - - - Caspase domain
KEHGHMLM_03101 1.23e-134 - - - L - - - reverse transcriptase
KEHGHMLM_03103 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KEHGHMLM_03105 2.24e-87 - - - - - - - -
KEHGHMLM_03106 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KEHGHMLM_03108 2.16e-39 yycQ - - S - - - Protein of unknown function (DUF2651)
KEHGHMLM_03109 1.01e-271 yycP - - - - - - -
KEHGHMLM_03110 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KEHGHMLM_03111 5.25e-111 yycN - - K - - - Acetyltransferase
KEHGHMLM_03112 1.06e-239 - - - S - - - aspartate phosphatase
KEHGHMLM_03114 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
KEHGHMLM_03115 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KEHGHMLM_03116 8.29e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
KEHGHMLM_03117 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KEHGHMLM_03118 5.58e-216 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KEHGHMLM_03119 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
KEHGHMLM_03120 8.13e-99 - - - S - - - Peptidase propeptide and YPEB domain
KEHGHMLM_03121 1.23e-41 - - - S - - - Peptidase propeptide and YPEB domain
KEHGHMLM_03122 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KEHGHMLM_03123 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KEHGHMLM_03124 2.83e-199 yycI - - S - - - protein conserved in bacteria
KEHGHMLM_03125 0.0 yycH - - S - - - protein conserved in bacteria
KEHGHMLM_03126 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_03127 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_03132 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KEHGHMLM_03133 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_03134 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KEHGHMLM_03135 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KEHGHMLM_03137 1.89e-22 yycC - - K - - - YycC-like protein
KEHGHMLM_03138 1.2e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
KEHGHMLM_03139 2.73e-186 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEHGHMLM_03140 1.45e-237 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEHGHMLM_03141 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KEHGHMLM_03142 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KEHGHMLM_03143 5.23e-205 yybS - - S - - - membrane
KEHGHMLM_03145 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
KEHGHMLM_03146 6.43e-88 yybR - - K - - - Transcriptional regulator
KEHGHMLM_03147 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
KEHGHMLM_03148 1.3e-89 - - - - - - - -
KEHGHMLM_03150 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03151 3.59e-141 - - - K - - - TipAS antibiotic-recognition domain
KEHGHMLM_03152 7.14e-184 - - - - - - - -
KEHGHMLM_03153 1.44e-86 - - - S - - - SnoaL-like domain
KEHGHMLM_03154 1.09e-159 yybG - - S - - - Pentapeptide repeat-containing protein
KEHGHMLM_03155 2.9e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03156 6.48e-211 yybE - - K - - - Transcriptional regulator
KEHGHMLM_03157 1.08e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
KEHGHMLM_03158 3.91e-94 yybC - - - - - - -
KEHGHMLM_03159 4.88e-161 - - - S - - - Metallo-beta-lactamase superfamily
KEHGHMLM_03160 4.54e-100 yybA - - K - - - transcriptional
KEHGHMLM_03161 2.44e-94 yjcF - - S - - - Acetyltransferase (GNAT) domain
KEHGHMLM_03162 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
KEHGHMLM_03163 1.84e-117 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
KEHGHMLM_03164 1.23e-84 - - - S - - - YjbR
KEHGHMLM_03165 7.09e-136 yyaP - - H - - - RibD C-terminal domain
KEHGHMLM_03166 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03167 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
KEHGHMLM_03168 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
KEHGHMLM_03169 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
KEHGHMLM_03170 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
KEHGHMLM_03171 4.88e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_03172 3.4e-227 ccpB - - K - - - Transcriptional regulator
KEHGHMLM_03173 1.34e-183 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KEHGHMLM_03174 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KEHGHMLM_03175 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KEHGHMLM_03176 1.44e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KEHGHMLM_03177 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KEHGHMLM_03178 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEHGHMLM_03179 7.41e-45 yyzM - - S - - - protein conserved in bacteria
KEHGHMLM_03180 5.34e-227 yyaD - - S - - - Membrane
KEHGHMLM_03181 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
KEHGHMLM_03182 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KEHGHMLM_03183 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
KEHGHMLM_03184 9.26e-98 - - - S - - - Bacterial PH domain
KEHGHMLM_03185 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KEHGHMLM_03186 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KEHGHMLM_03187 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KEHGHMLM_03188 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KEHGHMLM_03189 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
KEHGHMLM_03190 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEHGHMLM_03191 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KEHGHMLM_03192 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KEHGHMLM_03193 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KEHGHMLM_03194 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KEHGHMLM_03195 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KEHGHMLM_03196 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
KEHGHMLM_03197 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEHGHMLM_03198 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEHGHMLM_03201 3.44e-202 ydhU - - P ko:K07217 - ko00000 Catalase
KEHGHMLM_03202 1.86e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
KEHGHMLM_03203 4.19e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KEHGHMLM_03204 8.91e-217 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
KEHGHMLM_03205 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
KEHGHMLM_03206 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KEHGHMLM_03207 9.72e-301 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEHGHMLM_03208 5.86e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03209 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03210 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
KEHGHMLM_03211 9.44e-129 ydhK - - M - - - Protein of unknown function (DUF1541)
KEHGHMLM_03212 8.41e-235 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KEHGHMLM_03213 5.84e-112 - - - K - - - Acetyltransferase (GNAT) domain
KEHGHMLM_03215 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KEHGHMLM_03216 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
KEHGHMLM_03217 5e-162 - - - - - - - -
KEHGHMLM_03218 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KEHGHMLM_03219 5.16e-309 ydhD - - M - - - Glycosyl hydrolase
KEHGHMLM_03220 5.24e-158 ydhC - - K - - - FCD
KEHGHMLM_03221 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
KEHGHMLM_03222 2.43e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
KEHGHMLM_03223 3.29e-90 - - - K - - - Winged helix DNA-binding domain
KEHGHMLM_03224 1.84e-146 ydgI - - C - - - nitroreductase
KEHGHMLM_03225 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
KEHGHMLM_03226 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_03227 1.17e-106 - - - S - - - DinB family
KEHGHMLM_03228 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_03229 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
KEHGHMLM_03230 2.49e-114 yycN - - K - - - Acetyltransferase
KEHGHMLM_03231 7e-71 - - - S - - - DoxX-like family
KEHGHMLM_03232 5.99e-130 ydgC - - K - - - Bacterial regulatory proteins, tetR family
KEHGHMLM_03233 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
KEHGHMLM_03234 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
KEHGHMLM_03235 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KEHGHMLM_03236 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
KEHGHMLM_03237 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
KEHGHMLM_03239 5.33e-39 - - - - - - - -
KEHGHMLM_03240 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
KEHGHMLM_03242 8.92e-73 ydfQ - - CO - - - Thioredoxin
KEHGHMLM_03243 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
KEHGHMLM_03244 9.14e-160 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KEHGHMLM_03245 5.63e-65 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KEHGHMLM_03246 8.12e-144 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
KEHGHMLM_03247 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEHGHMLM_03248 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
KEHGHMLM_03249 6.51e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KEHGHMLM_03250 1.88e-223 - - - S - - - Alpha/beta hydrolase family
KEHGHMLM_03251 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
KEHGHMLM_03252 3.82e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEHGHMLM_03253 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_03255 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KEHGHMLM_03256 2.13e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KEHGHMLM_03257 9.91e-150 ydfE - - S - - - Flavin reductase like domain
KEHGHMLM_03258 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEHGHMLM_03259 2.4e-204 - - - EG - - - EamA-like transporter family
KEHGHMLM_03260 1.34e-189 - - - J - - - GNAT acetyltransferase
KEHGHMLM_03261 7.13e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KEHGHMLM_03262 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
KEHGHMLM_03263 3.74e-136 ydeS - - K - - - Transcriptional regulator
KEHGHMLM_03264 1.02e-259 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
KEHGHMLM_03265 2.87e-144 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
KEHGHMLM_03266 2.92e-90 ydeP - - K - - - Transcriptional regulator
KEHGHMLM_03267 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
KEHGHMLM_03268 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
KEHGHMLM_03269 6.63e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
KEHGHMLM_03270 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
KEHGHMLM_03271 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEHGHMLM_03272 1.49e-193 ydeK - - EG - - - -transporter
KEHGHMLM_03274 1e-110 - - - K - - - Transcriptional regulator C-terminal region
KEHGHMLM_03275 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
KEHGHMLM_03276 4.01e-92 - - - S - - - SNARE associated Golgi protein
KEHGHMLM_03277 6.53e-177 - - - T - - - COG0642 Signal transduction histidine kinase
KEHGHMLM_03278 5.54e-146 - - - T - - - Transcriptional regulator
KEHGHMLM_03279 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
KEHGHMLM_03280 7.34e-142 - - - - - - - -
KEHGHMLM_03281 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
KEHGHMLM_03282 3.74e-69 ydeH - - - - - - -
KEHGHMLM_03283 5.39e-277 ydeG - - EGP - - - Major facilitator superfamily
KEHGHMLM_03284 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEHGHMLM_03285 2.1e-211 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
KEHGHMLM_03286 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KEHGHMLM_03287 1.87e-214 - - - K - - - AraC-like ligand binding domain
KEHGHMLM_03288 1.14e-180 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KEHGHMLM_03289 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
KEHGHMLM_03290 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
KEHGHMLM_03291 2.26e-243 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
KEHGHMLM_03292 1.21e-52 - - - - - - - -
KEHGHMLM_03293 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KEHGHMLM_03294 3.28e-11 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
KEHGHMLM_03295 2.57e-62 ydeH - - - - - - -
KEHGHMLM_03296 1.93e-259 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KEHGHMLM_03297 9.8e-262 - - - KLT - - - Protein kinase domain
KEHGHMLM_03302 1.55e-188 - - - KLT - - - Protein kinase domain
KEHGHMLM_03313 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KEHGHMLM_03314 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
KEHGHMLM_03315 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
KEHGHMLM_03316 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KEHGHMLM_03317 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KEHGHMLM_03318 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
KEHGHMLM_03319 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
KEHGHMLM_03320 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KEHGHMLM_03321 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
KEHGHMLM_03322 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
KEHGHMLM_03323 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KEHGHMLM_03324 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KEHGHMLM_03325 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEHGHMLM_03326 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
KEHGHMLM_03327 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KEHGHMLM_03328 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
KEHGHMLM_03329 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
KEHGHMLM_03330 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
KEHGHMLM_03331 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KEHGHMLM_03332 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KEHGHMLM_03333 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KEHGHMLM_03334 4.19e-75 ydbP - - CO - - - Thioredoxin
KEHGHMLM_03335 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEHGHMLM_03337 1.49e-26 - - - S - - - Fur-regulated basic protein B
KEHGHMLM_03338 7.45e-280 ydbM - - I - - - acyl-CoA dehydrogenase
KEHGHMLM_03339 9.32e-70 ydbL - - - - - - -
KEHGHMLM_03340 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KEHGHMLM_03341 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_03342 1.32e-230 ydbI - - S - - - AI-2E family transporter
KEHGHMLM_03343 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEHGHMLM_03344 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
KEHGHMLM_03345 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KEHGHMLM_03346 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KEHGHMLM_03347 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
KEHGHMLM_03348 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
KEHGHMLM_03349 7.58e-79 ydbB - - G - - - Cupin domain
KEHGHMLM_03350 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
KEHGHMLM_03351 1.75e-189 ydbA - - P - - - EcsC protein family
KEHGHMLM_03352 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
KEHGHMLM_03353 1.67e-42 ydaS - - S - - - membrane
KEHGHMLM_03354 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KEHGHMLM_03355 2.14e-53 - - - - - - - -
KEHGHMLM_03356 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KEHGHMLM_03357 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KEHGHMLM_03358 0.0 ydaO - - E - - - amino acid
KEHGHMLM_03359 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
KEHGHMLM_03360 7.86e-304 ydaM - - M - - - Glycosyl transferase family group 2
KEHGHMLM_03361 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
KEHGHMLM_03362 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
KEHGHMLM_03363 7.79e-261 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
KEHGHMLM_03364 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEHGHMLM_03365 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
KEHGHMLM_03366 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
KEHGHMLM_03367 3.09e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KEHGHMLM_03368 5.24e-101 ydaG - - S - - - general stress protein
KEHGHMLM_03369 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KEHGHMLM_03370 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
KEHGHMLM_03371 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_03372 1e-127 ydaC - - Q - - - Methyltransferase domain
KEHGHMLM_03373 0.0 ydaB - - IQ - - - acyl-CoA ligase
KEHGHMLM_03374 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
KEHGHMLM_03375 4.97e-219 ycsN - - S - - - Oxidoreductase
KEHGHMLM_03376 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
KEHGHMLM_03377 7.67e-66 yczJ - - S - - - biosynthesis
KEHGHMLM_03379 3.44e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
KEHGHMLM_03380 3.8e-171 kipR - - K - - - Transcriptional regulator
KEHGHMLM_03381 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
KEHGHMLM_03382 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
KEHGHMLM_03383 2.74e-187 ycsI - - S - - - Belongs to the D-glutamate cyclase family
KEHGHMLM_03384 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
KEHGHMLM_03385 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
KEHGHMLM_03386 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KEHGHMLM_03388 7.69e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KEHGHMLM_03389 1.21e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
KEHGHMLM_03390 1.32e-126 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KEHGHMLM_03391 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
KEHGHMLM_03392 5.13e-267 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
KEHGHMLM_03393 2.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KEHGHMLM_03394 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
KEHGHMLM_03395 9.44e-75 - - - - - - - -
KEHGHMLM_03396 2.88e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
KEHGHMLM_03397 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
KEHGHMLM_03398 3.99e-134 ycnI - - S - - - protein conserved in bacteria
KEHGHMLM_03399 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_03400 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KEHGHMLM_03401 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEHGHMLM_03402 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEHGHMLM_03403 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KEHGHMLM_03404 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KEHGHMLM_03405 1.68e-60 ycnE - - S - - - Monooxygenase
KEHGHMLM_03406 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
KEHGHMLM_03407 1.38e-196 ycnC - - K - - - Transcriptional regulator
KEHGHMLM_03408 0.0 ycnB - - EGP - - - the major facilitator superfamily
KEHGHMLM_03409 2.33e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KEHGHMLM_03410 1.33e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_03411 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03412 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03413 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KEHGHMLM_03414 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KEHGHMLM_03415 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
KEHGHMLM_03417 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
KEHGHMLM_03418 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KEHGHMLM_03419 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_03420 7.38e-273 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
KEHGHMLM_03421 4.82e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KEHGHMLM_03422 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
KEHGHMLM_03423 2.39e-296 gerKC - - S ko:K06297 - ko00000 spore germination
KEHGHMLM_03424 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
KEHGHMLM_03426 0.0 yclG - - M - - - Pectate lyase superfamily protein
KEHGHMLM_03427 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
KEHGHMLM_03428 7.82e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
KEHGHMLM_03429 1.34e-103 yclD - - - - - - -
KEHGHMLM_03430 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
KEHGHMLM_03431 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KEHGHMLM_03432 1.35e-141 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KEHGHMLM_03433 8.83e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
KEHGHMLM_03434 2.49e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KEHGHMLM_03435 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KEHGHMLM_03436 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
KEHGHMLM_03437 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
KEHGHMLM_03438 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
KEHGHMLM_03439 0.0 ycxD - - K - - - GntR family transcriptional regulator
KEHGHMLM_03440 9.36e-205 ycxC - - EG - - - EamA-like transporter family
KEHGHMLM_03441 2.1e-122 - - - S - - - YcxB-like protein
KEHGHMLM_03442 1.54e-288 - - - EGP - - - Major Facilitator Superfamily
KEHGHMLM_03443 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
KEHGHMLM_03444 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
KEHGHMLM_03445 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_03446 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEHGHMLM_03447 6.05e-86 hxlR - - K - - - transcriptional
KEHGHMLM_03448 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
KEHGHMLM_03449 6.28e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
KEHGHMLM_03450 2.16e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
KEHGHMLM_03451 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
KEHGHMLM_03452 4.78e-91 nin - - S - - - Competence protein J (ComJ)
KEHGHMLM_03453 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KEHGHMLM_03454 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
KEHGHMLM_03456 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KEHGHMLM_03457 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
KEHGHMLM_03458 3.22e-289 yciC - - S - - - GTPases (G3E family)
KEHGHMLM_03459 2.97e-131 - - - M - - - ErfK YbiS YcfS YnhG
KEHGHMLM_03460 7.92e-218 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
KEHGHMLM_03461 6.43e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
KEHGHMLM_03462 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
KEHGHMLM_03463 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEHGHMLM_03464 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KEHGHMLM_03465 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
KEHGHMLM_03466 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
KEHGHMLM_03467 2.01e-243 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KEHGHMLM_03468 1.34e-199 ycgS - - I - - - alpha/beta hydrolase fold
KEHGHMLM_03469 2.62e-186 ycgR - - S ko:K07089 - ko00000 permeases
KEHGHMLM_03470 3.03e-193 ycgQ - - S ko:K08986 - ko00000 membrane
KEHGHMLM_03471 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
KEHGHMLM_03472 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEHGHMLM_03473 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
KEHGHMLM_03474 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
KEHGHMLM_03475 4.31e-184 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
KEHGHMLM_03476 2.7e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
KEHGHMLM_03477 8.01e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
KEHGHMLM_03478 1.51e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
KEHGHMLM_03479 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KEHGHMLM_03481 3.09e-139 tmrB - - S - - - AAA domain
KEHGHMLM_03482 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KEHGHMLM_03483 4.4e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
KEHGHMLM_03484 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_03485 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
KEHGHMLM_03486 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
KEHGHMLM_03487 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
KEHGHMLM_03488 0.0 mdr - - EGP - - - the major facilitator superfamily
KEHGHMLM_03489 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KEHGHMLM_03490 1.69e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KEHGHMLM_03491 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
KEHGHMLM_03492 2.72e-105 ycgB - - - - - - -
KEHGHMLM_03493 0.0 ycgA - - S - - - Membrane
KEHGHMLM_03494 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
KEHGHMLM_03495 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KEHGHMLM_03496 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KEHGHMLM_03497 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
KEHGHMLM_03498 1.97e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KEHGHMLM_03499 1.07e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
KEHGHMLM_03500 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
KEHGHMLM_03501 2.96e-245 yceH - - P - - - Belongs to the TelA family
KEHGHMLM_03502 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
KEHGHMLM_03503 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
KEHGHMLM_03504 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KEHGHMLM_03505 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
KEHGHMLM_03506 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
KEHGHMLM_03507 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KEHGHMLM_03508 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KEHGHMLM_03509 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KEHGHMLM_03510 1.86e-219 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KEHGHMLM_03511 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
KEHGHMLM_03512 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
KEHGHMLM_03513 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
KEHGHMLM_03514 4.57e-124 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
KEHGHMLM_03515 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_03516 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_03517 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
KEHGHMLM_03518 2.38e-222 yccK - - C - - - Aldo keto reductase
KEHGHMLM_03519 1.55e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KEHGHMLM_03520 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KEHGHMLM_03521 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KEHGHMLM_03522 1.58e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KEHGHMLM_03523 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
KEHGHMLM_03524 6.61e-73 - - - S - - - RDD family
KEHGHMLM_03525 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KEHGHMLM_03526 2.06e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KEHGHMLM_03527 4.42e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
KEHGHMLM_03528 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
KEHGHMLM_03529 4.86e-259 ycbU - - E - - - Selenocysteine lyase
KEHGHMLM_03530 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KEHGHMLM_03531 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KEHGHMLM_03532 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KEHGHMLM_03533 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
KEHGHMLM_03534 2.7e-174 ycbR - - T - - - vWA found in TerF C terminus
KEHGHMLM_03535 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
KEHGHMLM_03536 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
KEHGHMLM_03537 2.87e-148 - - - S - - - ABC-2 family transporter protein
KEHGHMLM_03538 1.07e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_03539 9.21e-216 ycbM - - T - - - Histidine kinase
KEHGHMLM_03540 2.24e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KEHGHMLM_03541 2.18e-173 eamA1 - - EG - - - spore germination
KEHGHMLM_03542 3.57e-32 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
KEHGHMLM_03543 7.39e-224 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
KEHGHMLM_03544 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
KEHGHMLM_03545 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
KEHGHMLM_03546 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KEHGHMLM_03547 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03548 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEHGHMLM_03549 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
KEHGHMLM_03550 9.96e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
KEHGHMLM_03551 2.39e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_03552 1.25e-237 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KEHGHMLM_03553 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
KEHGHMLM_03554 2.8e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
KEHGHMLM_03555 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KEHGHMLM_03556 3.59e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KEHGHMLM_03558 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KEHGHMLM_03559 1.5e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEHGHMLM_03560 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03561 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEHGHMLM_03562 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KEHGHMLM_03563 1.24e-09 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
KEHGHMLM_03564 1.58e-59 ybfN - - - - - - -
KEHGHMLM_03565 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KEHGHMLM_03566 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
KEHGHMLM_03567 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEHGHMLM_03568 1.59e-213 - - - S - - - Alpha/beta hydrolase family
KEHGHMLM_03570 1.44e-229 mpr - - M - - - Belongs to the peptidase S1B family
KEHGHMLM_03571 2.18e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KEHGHMLM_03572 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
KEHGHMLM_03573 6.15e-207 ybfH - - EG - - - EamA-like transporter family
KEHGHMLM_03574 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
KEHGHMLM_03576 2.04e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03577 1e-216 ybfA - - K - - - FR47-like protein
KEHGHMLM_03578 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
KEHGHMLM_03579 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
KEHGHMLM_03580 1.11e-207 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
KEHGHMLM_03581 0.0 ybeC - - E - - - amino acid
KEHGHMLM_03582 1.11e-54 ybyB - - - - - - -
KEHGHMLM_03583 2.1e-269 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
KEHGHMLM_03584 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
KEHGHMLM_03585 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
KEHGHMLM_03586 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
KEHGHMLM_03587 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_03588 1.09e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
KEHGHMLM_03589 1.05e-192 ybdN - - - - - - -
KEHGHMLM_03590 4.44e-175 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KEHGHMLM_03592 1.08e-216 - - - T - - - His Kinase A (phospho-acceptor) domain
KEHGHMLM_03593 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
KEHGHMLM_03594 6.63e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KEHGHMLM_03595 1.66e-73 - - - - - - - -
KEHGHMLM_03596 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
KEHGHMLM_03597 9.45e-67 - - - K - - - Helix-turn-helix domain
KEHGHMLM_03598 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
KEHGHMLM_03599 1.6e-63 - - - - - - - -
KEHGHMLM_03601 9.84e-121 ybcF - - P - - - carbonic anhydrase
KEHGHMLM_03602 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
KEHGHMLM_03603 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KEHGHMLM_03604 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEHGHMLM_03605 1.25e-154 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
KEHGHMLM_03606 2.99e-217 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KEHGHMLM_03607 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KEHGHMLM_03608 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KEHGHMLM_03609 1.39e-290 ybbR - - S - - - protein conserved in bacteria
KEHGHMLM_03610 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEHGHMLM_03611 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KEHGHMLM_03612 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KEHGHMLM_03618 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
KEHGHMLM_03619 3.13e-114 ybbJ - - J - - - acetyltransferase
KEHGHMLM_03620 9.51e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KEHGHMLM_03621 3.01e-191 ybbH - - K - - - transcriptional
KEHGHMLM_03622 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03623 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
KEHGHMLM_03624 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
KEHGHMLM_03625 8.14e-303 ybbC - - S - - - protein conserved in bacteria
KEHGHMLM_03626 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
KEHGHMLM_03627 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
KEHGHMLM_03628 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03629 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03630 2.71e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
KEHGHMLM_03631 2.34e-203 ybaS - - S - - - Na -dependent transporter
KEHGHMLM_03633 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
KEHGHMLM_03635 5.68e-233 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KEHGHMLM_03636 2.13e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
KEHGHMLM_03637 3.98e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
KEHGHMLM_03638 4.91e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KEHGHMLM_03639 2.22e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KEHGHMLM_03640 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
KEHGHMLM_03641 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KEHGHMLM_03642 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KEHGHMLM_03643 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KEHGHMLM_03644 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KEHGHMLM_03645 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
KEHGHMLM_03646 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KEHGHMLM_03647 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KEHGHMLM_03648 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KEHGHMLM_03649 2.72e-182 - - - L - - - Belongs to the 'phage' integrase family
KEHGHMLM_03650 1.91e-61 xkdA - - E - - - IrrE N-terminal-like domain
KEHGHMLM_03651 1.28e-53 - - - S - - - Protein of unknown function (DUF4064)
KEHGHMLM_03652 1.53e-84 - - - - - - - -
KEHGHMLM_03653 5.15e-28 - - - K - - - sequence-specific DNA binding
KEHGHMLM_03655 6.84e-48 - - - - - - - -
KEHGHMLM_03656 6.76e-86 - - - S - - - DNA binding
KEHGHMLM_03657 6.31e-87 - - - - - - - -
KEHGHMLM_03663 1.89e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
KEHGHMLM_03664 8.87e-172 recT - - L ko:K07455 - ko00000,ko03400 RecT family
KEHGHMLM_03665 7.78e-42 yqaL - - L - - - DnaD domain protein
KEHGHMLM_03666 1.13e-162 yqaM - - L - - - IstB-like ATP binding protein
KEHGHMLM_03668 6.24e-95 - - - - - - - -
KEHGHMLM_03669 2.59e-70 - - - S - - - Protein of unknown function (DUF1064)
KEHGHMLM_03671 1.85e-29 yqaO - - S - - - Phage-like element PBSX protein XtrA
KEHGHMLM_03673 8.96e-98 - - - - - - - -
KEHGHMLM_03675 1.3e-76 - - - - - - - -
KEHGHMLM_03676 0.000179 - - - S - - - YopX protein
KEHGHMLM_03682 1.77e-103 - - - L - - - Transposase
KEHGHMLM_03685 5.54e-59 - - - L ko:K07474 - ko00000 Terminase small subunit
KEHGHMLM_03686 1.52e-247 - - - S - - - Phage terminase large subunit
KEHGHMLM_03688 2.47e-149 - - - S - - - Phage portal protein, SPP1 Gp6-like
KEHGHMLM_03689 1.08e-116 - - - S - - - Phage Mu protein F like protein
KEHGHMLM_03691 3.09e-55 - - - S - - - Phage minor structural protein GP20
KEHGHMLM_03692 4.89e-61 - - - S - - - viral capsid
KEHGHMLM_03694 4.32e-38 - - - S - - - Phage gp6-like head-tail connector protein
KEHGHMLM_03695 2.28e-37 - - - S - - - Phage head-tail joining protein
KEHGHMLM_03696 1.22e-47 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KEHGHMLM_03697 1.62e-37 - - - S - - - Protein of unknown function (DUF3168)
KEHGHMLM_03698 5.25e-43 - - - S - - - Phage tail tube protein
KEHGHMLM_03699 9.98e-07 - - - GI - - - Pectic acid lyase
KEHGHMLM_03700 3.65e-37 - - - S - - - Phage tail assembly chaperone protein, TAC
KEHGHMLM_03701 1.41e-182 - - - - - - - -
KEHGHMLM_03702 7.91e-12 - - - S - - - phage tail component
KEHGHMLM_03703 2.79e-243 - - - L - - - Phage minor structural protein
KEHGHMLM_03708 2.42e-36 xhlA - - S - - - Haemolysin XhlA
KEHGHMLM_03709 1.58e-41 xhlB - - S - - - SPP1 phage holin
KEHGHMLM_03710 1.39e-138 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
KEHGHMLM_03715 1.12e-36 - - - K - - - Helix-turn-helix domain
KEHGHMLM_03717 2.85e-113 - - - E - - - Zn peptidase
KEHGHMLM_03720 1.55e-192 ydjC - - S - - - Abhydrolase domain containing 18
KEHGHMLM_03721 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
KEHGHMLM_03722 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KEHGHMLM_03723 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
KEHGHMLM_03724 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KEHGHMLM_03725 2.65e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
KEHGHMLM_03726 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEHGHMLM_03727 2.2e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
KEHGHMLM_03728 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
KEHGHMLM_03729 1.08e-245 - - - S - - - Ion transport 2 domain protein
KEHGHMLM_03730 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KEHGHMLM_03731 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
KEHGHMLM_03732 1.79e-84 ydjM - - M - - - Lytic transglycolase
KEHGHMLM_03733 1.09e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
KEHGHMLM_03735 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
KEHGHMLM_03736 4.9e-200 - - - I - - - Alpha/beta hydrolase family
KEHGHMLM_03737 7.65e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
KEHGHMLM_03738 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
KEHGHMLM_03739 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
KEHGHMLM_03740 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEHGHMLM_03741 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
KEHGHMLM_03742 8.42e-281 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KEHGHMLM_03743 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
KEHGHMLM_03744 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KEHGHMLM_03745 3.27e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KEHGHMLM_03746 5.85e-165 yebC - - M - - - Membrane
KEHGHMLM_03748 1.08e-119 yebE - - S - - - UPF0316 protein
KEHGHMLM_03749 3.13e-38 yebG - - S - - - NETI protein
KEHGHMLM_03750 7.63e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KEHGHMLM_03751 9e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KEHGHMLM_03752 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KEHGHMLM_03753 2.04e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KEHGHMLM_03754 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEHGHMLM_03755 1.91e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEHGHMLM_03756 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEHGHMLM_03757 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KEHGHMLM_03758 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KEHGHMLM_03759 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KEHGHMLM_03760 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KEHGHMLM_03761 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KEHGHMLM_03762 1.06e-95 - - - K - - - helix_turn_helix ASNC type
KEHGHMLM_03763 2.04e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
KEHGHMLM_03764 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
KEHGHMLM_03765 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
KEHGHMLM_03766 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
KEHGHMLM_03767 6.27e-67 yerC - - S - - - protein conserved in bacteria
KEHGHMLM_03768 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
KEHGHMLM_03769 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KEHGHMLM_03770 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KEHGHMLM_03771 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KEHGHMLM_03772 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
KEHGHMLM_03773 7.33e-252 yerI - - S - - - homoserine kinase type II (protein kinase fold)
KEHGHMLM_03774 1.32e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
KEHGHMLM_03775 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEHGHMLM_03776 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEHGHMLM_03777 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KEHGHMLM_03778 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEHGHMLM_03779 7.27e-191 yerO - - K - - - Transcriptional regulator
KEHGHMLM_03780 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KEHGHMLM_03781 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KEHGHMLM_03782 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEHGHMLM_03783 1.14e-27 - - - - - - - -
KEHGHMLM_03784 0.0 - - - K - - - SIR2-like domain
KEHGHMLM_03786 2.59e-123 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
KEHGHMLM_03787 0.000203 - - - - - - - -
KEHGHMLM_03788 8.47e-55 - - - S - - - Immunity protein 22
KEHGHMLM_03789 2.91e-228 - - - S - - - Bacterial EndoU nuclease
KEHGHMLM_03790 2.85e-224 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
KEHGHMLM_03792 1.22e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
KEHGHMLM_03794 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
KEHGHMLM_03796 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
KEHGHMLM_03797 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
KEHGHMLM_03798 1.23e-195 yesF - - GM - - - NAD(P)H-binding
KEHGHMLM_03799 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
KEHGHMLM_03800 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
KEHGHMLM_03801 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
KEHGHMLM_03802 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
KEHGHMLM_03804 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
KEHGHMLM_03805 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KEHGHMLM_03806 3.27e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
KEHGHMLM_03807 5.06e-315 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KEHGHMLM_03808 4.08e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_03809 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_03810 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
KEHGHMLM_03811 0.0 yesS - - K - - - Transcriptional regulator
KEHGHMLM_03812 2.22e-165 - - - E - - - GDSL-like Lipase/Acylhydrolase
KEHGHMLM_03813 6.93e-161 yesU - - S - - - Domain of unknown function (DUF1961)
KEHGHMLM_03814 9.47e-144 - - - S - - - Protein of unknown function, DUF624
KEHGHMLM_03815 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
KEHGHMLM_03816 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
KEHGHMLM_03817 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
KEHGHMLM_03818 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
KEHGHMLM_03819 0.0 yetA - - - - - - -
KEHGHMLM_03820 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KEHGHMLM_03821 2.78e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
KEHGHMLM_03822 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KEHGHMLM_03823 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
KEHGHMLM_03824 1.49e-156 yetF - - S - - - membrane
KEHGHMLM_03825 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
KEHGHMLM_03826 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEHGHMLM_03827 9.79e-45 - - - - - - - -
KEHGHMLM_03828 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KEHGHMLM_03829 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
KEHGHMLM_03830 7.32e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
KEHGHMLM_03831 2.57e-38 yetM - - CH - - - FAD binding domain
KEHGHMLM_03832 2.11e-94 - - - - - - - -
KEHGHMLM_03834 2.66e-137 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
KEHGHMLM_03835 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
KEHGHMLM_03836 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
KEHGHMLM_03837 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KEHGHMLM_03838 1.46e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
KEHGHMLM_03839 2.77e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
KEHGHMLM_03840 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
KEHGHMLM_03841 9.92e-286 yfnE - - S - - - Glycosyltransferase like family 2
KEHGHMLM_03842 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
KEHGHMLM_03843 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03844 2.13e-167 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KEHGHMLM_03845 1.39e-311 yfnA - - E ko:K03294 - ko00000 amino acid
KEHGHMLM_03846 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KEHGHMLM_03847 5.14e-161 yfmS - - NT - - - chemotaxis protein
KEHGHMLM_03848 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEHGHMLM_03849 3.75e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
KEHGHMLM_03850 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
KEHGHMLM_03851 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
KEHGHMLM_03852 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KEHGHMLM_03853 8.46e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
KEHGHMLM_03854 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
KEHGHMLM_03855 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
KEHGHMLM_03856 1.72e-268 - - - G - - - Major Facilitator Superfamily
KEHGHMLM_03857 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
KEHGHMLM_03858 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KEHGHMLM_03859 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03860 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03861 6.66e-211 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KEHGHMLM_03862 2.55e-31 - - - S - - - Protein of unknown function (DUF3212)
KEHGHMLM_03863 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
KEHGHMLM_03864 1.42e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
KEHGHMLM_03865 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KEHGHMLM_03866 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
KEHGHMLM_03867 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KEHGHMLM_03868 6.89e-231 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
KEHGHMLM_03869 2.18e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
KEHGHMLM_03870 1.98e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
KEHGHMLM_03871 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KEHGHMLM_03872 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KEHGHMLM_03873 3.42e-157 yflK - - S - - - protein conserved in bacteria
KEHGHMLM_03874 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
KEHGHMLM_03875 6.9e-27 yflI - - - - - - -
KEHGHMLM_03876 1.48e-65 yflH - - S - - - Protein of unknown function (DUF3243)
KEHGHMLM_03877 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KEHGHMLM_03878 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KEHGHMLM_03879 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KEHGHMLM_03880 2.2e-86 ydhN1 - - S - - - Domain of unknown function (DUF1992)
KEHGHMLM_03881 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
KEHGHMLM_03882 1.84e-31 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
KEHGHMLM_03883 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03884 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KEHGHMLM_03885 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
KEHGHMLM_03886 1.02e-158 frp - - C - - - nitroreductase
KEHGHMLM_03887 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KEHGHMLM_03888 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
KEHGHMLM_03889 2.07e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03890 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
KEHGHMLM_03891 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEHGHMLM_03892 1.03e-66 yfkI - - S - - - gas vesicle protein
KEHGHMLM_03893 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KEHGHMLM_03894 2.74e-11 - - - - - - - -
KEHGHMLM_03895 2.7e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
KEHGHMLM_03896 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
KEHGHMLM_03897 3.69e-189 yfkD - - S - - - YfkD-like protein
KEHGHMLM_03898 2.57e-190 yfkC - - M - - - Mechanosensitive ion channel
KEHGHMLM_03899 1.69e-281 yfkA - - S - - - YfkB-like domain
KEHGHMLM_03900 3.26e-36 yfjT - - - - - - -
KEHGHMLM_03901 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
KEHGHMLM_03902 3.96e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KEHGHMLM_03903 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
KEHGHMLM_03904 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KEHGHMLM_03905 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEHGHMLM_03906 3.04e-59 - - - S - - - YfzA-like protein
KEHGHMLM_03907 6.18e-237 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEHGHMLM_03908 1.47e-105 yfjM - - S - - - Psort location Cytoplasmic, score
KEHGHMLM_03910 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KEHGHMLM_03911 6.47e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KEHGHMLM_03912 3.29e-262 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEHGHMLM_03913 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KEHGHMLM_03914 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
KEHGHMLM_03915 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
KEHGHMLM_03916 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
KEHGHMLM_03917 1.3e-101 - - - S - - - Family of unknown function (DUF5381)
KEHGHMLM_03918 3.52e-130 yfjD - - S - - - Family of unknown function (DUF5381)
KEHGHMLM_03919 2.5e-185 yfjC - - - - - - -
KEHGHMLM_03920 5.56e-270 yfjB - - - - - - -
KEHGHMLM_03921 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
KEHGHMLM_03922 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KEHGHMLM_03923 3.03e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
KEHGHMLM_03924 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KEHGHMLM_03925 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
KEHGHMLM_03926 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
KEHGHMLM_03927 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
KEHGHMLM_03928 3.34e-83 yfiD3 - - S - - - DoxX
KEHGHMLM_03929 4.21e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KEHGHMLM_03931 1.98e-271 baeS - - T - - - Histidine kinase
KEHGHMLM_03932 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
KEHGHMLM_03933 6.95e-211 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KEHGHMLM_03934 8.44e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KEHGHMLM_03935 3.44e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
KEHGHMLM_03936 1.89e-128 padR - - K - - - transcriptional
KEHGHMLM_03937 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
KEHGHMLM_03938 3.8e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KEHGHMLM_03939 4e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
KEHGHMLM_03940 0.0 yfiU - - EGP - - - the major facilitator superfamily
KEHGHMLM_03941 1.27e-104 yfiV - - K - - - transcriptional
KEHGHMLM_03942 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KEHGHMLM_03943 9.42e-232 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KEHGHMLM_03944 1.27e-224 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03945 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEHGHMLM_03946 7.61e-215 yfhB - - S - - - PhzF family
KEHGHMLM_03947 2.87e-138 yfhC - - C - - - nitroreductase
KEHGHMLM_03948 8.86e-35 yfhD - - S - - - YfhD-like protein
KEHGHMLM_03950 2.19e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
KEHGHMLM_03951 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KEHGHMLM_03952 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
KEHGHMLM_03954 1.65e-266 yfhI - - EGP - - - -transporter
KEHGHMLM_03955 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
KEHGHMLM_03956 8.95e-60 yfhJ - - S - - - WVELL protein
KEHGHMLM_03957 4.18e-118 yfhK - - T - - - Bacterial SH3 domain homologues
KEHGHMLM_03958 1.66e-62 yfhL - - S - - - SdpI/YhfL protein family
KEHGHMLM_03959 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
KEHGHMLM_03960 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
KEHGHMLM_03961 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KEHGHMLM_03962 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
KEHGHMLM_03963 5.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
KEHGHMLM_03964 1.73e-48 yfhS - - - - - - -
KEHGHMLM_03965 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KEHGHMLM_03966 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
KEHGHMLM_03967 2.01e-49 ygaB - - S - - - YgaB-like protein
KEHGHMLM_03968 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KEHGHMLM_03969 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
KEHGHMLM_03970 1.87e-238 ygaE - - S - - - Membrane
KEHGHMLM_03971 5.64e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
KEHGHMLM_03972 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
KEHGHMLM_03973 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KEHGHMLM_03974 5.46e-74 ygzB - - S - - - UPF0295 protein
KEHGHMLM_03975 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
KEHGHMLM_03976 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KEHGHMLM_03977 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
KEHGHMLM_03978 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KEHGHMLM_03979 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KEHGHMLM_03980 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KEHGHMLM_03981 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KEHGHMLM_03982 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
KEHGHMLM_03983 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KEHGHMLM_03984 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KEHGHMLM_03985 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KEHGHMLM_03986 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
KEHGHMLM_03987 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KEHGHMLM_03988 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KEHGHMLM_03989 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEHGHMLM_03990 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KEHGHMLM_03991 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
KEHGHMLM_03992 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KEHGHMLM_03993 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KEHGHMLM_03994 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KEHGHMLM_03995 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KEHGHMLM_03996 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KEHGHMLM_03997 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KEHGHMLM_03998 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KEHGHMLM_03999 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEHGHMLM_04000 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEHGHMLM_04001 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
KEHGHMLM_04002 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KEHGHMLM_04003 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KEHGHMLM_04004 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KEHGHMLM_04005 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KEHGHMLM_04006 2.04e-227 ybaC - - S - - - Alpha/beta hydrolase family
KEHGHMLM_04007 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KEHGHMLM_04008 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KEHGHMLM_04009 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KEHGHMLM_04010 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KEHGHMLM_04011 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KEHGHMLM_04012 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KEHGHMLM_04013 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KEHGHMLM_04014 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KEHGHMLM_04015 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KEHGHMLM_04016 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KEHGHMLM_04017 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KEHGHMLM_04018 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KEHGHMLM_04019 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KEHGHMLM_04020 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KEHGHMLM_04021 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEHGHMLM_04022 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KEHGHMLM_04023 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KEHGHMLM_04024 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KEHGHMLM_04025 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KEHGHMLM_04026 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KEHGHMLM_04027 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KEHGHMLM_04028 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KEHGHMLM_04029 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KEHGHMLM_04030 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KEHGHMLM_04031 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KEHGHMLM_04032 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KEHGHMLM_04033 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KEHGHMLM_04034 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KEHGHMLM_04035 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEHGHMLM_04036 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KEHGHMLM_04037 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEHGHMLM_04038 1.1e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEHGHMLM_04039 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEHGHMLM_04040 4.33e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KEHGHMLM_04041 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KEHGHMLM_04042 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KEHGHMLM_04043 2.5e-185 ybaJ - - Q - - - Methyltransferase domain
KEHGHMLM_04044 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
KEHGHMLM_04045 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
KEHGHMLM_04046 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KEHGHMLM_04047 1.04e-122 gerD - - - ko:K06294 - ko00000 -
KEHGHMLM_04048 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
KEHGHMLM_04049 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
KEHGHMLM_04050 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KEHGHMLM_04051 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEHGHMLM_04052 1.81e-41 yazB - - K - - - transcriptional
KEHGHMLM_04053 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KEHGHMLM_04054 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KEHGHMLM_04055 6.7e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KEHGHMLM_04056 4.4e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
KEHGHMLM_04057 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
KEHGHMLM_04058 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEHGHMLM_04059 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KEHGHMLM_04060 2.23e-194 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
KEHGHMLM_04061 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KEHGHMLM_04062 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KEHGHMLM_04063 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KEHGHMLM_04064 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KEHGHMLM_04065 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KEHGHMLM_04066 2.41e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
KEHGHMLM_04067 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
KEHGHMLM_04068 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
KEHGHMLM_04071 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
KEHGHMLM_04072 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KEHGHMLM_04073 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
KEHGHMLM_04074 1.91e-66 yabP - - S - - - Sporulation protein YabP
KEHGHMLM_04075 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KEHGHMLM_04076 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KEHGHMLM_04077 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KEHGHMLM_04078 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
KEHGHMLM_04079 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KEHGHMLM_04080 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
KEHGHMLM_04081 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KEHGHMLM_04082 4.16e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KEHGHMLM_04083 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEHGHMLM_04084 1.43e-306 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KEHGHMLM_04085 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KEHGHMLM_04086 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
KEHGHMLM_04087 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KEHGHMLM_04088 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KEHGHMLM_04089 5.32e-53 veg - - S - - - protein conserved in bacteria
KEHGHMLM_04090 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
KEHGHMLM_04091 4.14e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KEHGHMLM_04092 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KEHGHMLM_04093 7.43e-281 yabE - - T - - - protein conserved in bacteria
KEHGHMLM_04094 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
KEHGHMLM_04095 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KEHGHMLM_04096 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
KEHGHMLM_04097 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KEHGHMLM_04098 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KEHGHMLM_04099 1.34e-176 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
KEHGHMLM_04100 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
KEHGHMLM_04101 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
KEHGHMLM_04102 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KEHGHMLM_04103 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
KEHGHMLM_04104 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
KEHGHMLM_04105 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KEHGHMLM_04106 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
KEHGHMLM_04107 3.4e-258 yaaN - - P - - - Belongs to the TelA family
KEHGHMLM_04108 3.83e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KEHGHMLM_04109 1.82e-41 csfB - - S - - - Inhibitor of sigma-G Gin
KEHGHMLM_04110 3.7e-233 yaaC - - S - - - YaaC-like Protein
KEHGHMLM_04111 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KEHGHMLM_04112 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KEHGHMLM_04113 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KEHGHMLM_04114 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KEHGHMLM_04115 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KEHGHMLM_04117 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
KEHGHMLM_04118 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
KEHGHMLM_04119 1.22e-274 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
KEHGHMLM_04120 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
KEHGHMLM_04121 3e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KEHGHMLM_04122 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEHGHMLM_04123 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KEHGHMLM_04124 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KEHGHMLM_04125 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
KEHGHMLM_04126 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
KEHGHMLM_04129 2.4e-76 - - - - - - - -
KEHGHMLM_04131 2.66e-47 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
KEHGHMLM_04132 8.83e-209 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
KEHGHMLM_04133 1.98e-54 - - - - - - - -
KEHGHMLM_04135 1.86e-23 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
KEHGHMLM_04137 3.2e-39 - - - - - - - -
KEHGHMLM_04139 1.88e-21 - - - - - - - -
KEHGHMLM_04140 3.88e-111 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KEHGHMLM_04141 2.68e-39 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KEHGHMLM_04142 7.5e-70 - - - K - - - DNA binding
KEHGHMLM_04145 6.54e-35 - - - - - - - -
KEHGHMLM_04147 3.34e-39 - - - L - - - Phage integrase family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)