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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKBNCOEO_00002	1.31e-37	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_00003	3.92e-22	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_00004	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HKBNCOEO_00005	1e-91	-	-	-	-	-	-	-	-
HKBNCOEO_00006	9.44e-314	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HKBNCOEO_00007	1.59e-241	-	-	-	-	-	-	-	-
HKBNCOEO_00008	1.21e-219	-	-	-	S	ko:K21688	-	ko00000	G5
HKBNCOEO_00009	1.59e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HKBNCOEO_00010	1.83e-156	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HKBNCOEO_00011	2e-204	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKBNCOEO_00012	2.94e-282	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HKBNCOEO_00013	3.63e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HKBNCOEO_00014	1.65e-283	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HKBNCOEO_00015	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HKBNCOEO_00016	2.09e-244	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKBNCOEO_00017	7.37e-272	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HKBNCOEO_00018	2.9e-167	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKBNCOEO_00019	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HKBNCOEO_00020	8.2e-304	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HKBNCOEO_00021	2.17e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HKBNCOEO_00022	5.12e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HKBNCOEO_00023	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HKBNCOEO_00024	4.15e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HKBNCOEO_00025	1.26e-19	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
HKBNCOEO_00026	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKBNCOEO_00027	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKBNCOEO_00028	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKBNCOEO_00029	1.2e-236	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HKBNCOEO_00030	1.05e-163	-	-	-	-	-	-	-	-
HKBNCOEO_00031	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKBNCOEO_00032	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKBNCOEO_00033	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HKBNCOEO_00034	5.35e-307	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKBNCOEO_00035	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HKBNCOEO_00036	5.07e-283	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HKBNCOEO_00037	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKBNCOEO_00038	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HKBNCOEO_00039	1.51e-297	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00040	9.28e-170	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKBNCOEO_00041	2.56e-212	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKBNCOEO_00042	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKBNCOEO_00043	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HKBNCOEO_00044	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKBNCOEO_00045	3.57e-157	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKBNCOEO_00046	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_00047	8.44e-262	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKBNCOEO_00048	3.08e-267	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HKBNCOEO_00049	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HKBNCOEO_00050	9.07e-206	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HKBNCOEO_00051	1.33e-105	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKBNCOEO_00052	1.15e-196	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HKBNCOEO_00053	6.49e-217	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HKBNCOEO_00054	1.79e-221	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00055	3.69e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00056	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKBNCOEO_00057	1.58e-200	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HKBNCOEO_00058	5.3e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
HKBNCOEO_00059	2.3e-186	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_00060	1.43e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKBNCOEO_00061	1.66e-42	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKBNCOEO_00063	1.6e-291	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HKBNCOEO_00064	1.56e-294	-	-	-	G	-	-	-	polysaccharide deacetylase
HKBNCOEO_00065	2.92e-247	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKBNCOEO_00066	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKBNCOEO_00067	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HKBNCOEO_00068	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKBNCOEO_00069	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HKBNCOEO_00070	7.01e-293	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HKBNCOEO_00071	1.58e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKBNCOEO_00072	1.72e-213	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HKBNCOEO_00073	1.15e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
HKBNCOEO_00074	9.55e-271	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HKBNCOEO_00075	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HKBNCOEO_00076	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HKBNCOEO_00077	4.75e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HKBNCOEO_00078	1.24e-281	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HKBNCOEO_00079	3.52e-166	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00080	1.21e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HKBNCOEO_00081	6.46e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKBNCOEO_00082	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HKBNCOEO_00083	1.23e-233	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKBNCOEO_00084	1.31e-302	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKBNCOEO_00085	1.49e-294	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKBNCOEO_00086	5.66e-75	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKBNCOEO_00087	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKBNCOEO_00088	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKBNCOEO_00089	4.49e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_00090	1.99e-282	-	-	-	G	-	-	-	Transmembrane secretion effector
HKBNCOEO_00091	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKBNCOEO_00092	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HKBNCOEO_00093	2.62e-201	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKBNCOEO_00094	8.62e-155	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00095	1.55e-178	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00096	1.68e-132	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HKBNCOEO_00097	9.29e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00098	2.51e-281	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HKBNCOEO_00099	3.71e-47	-	-	-	T	-	-	-	Histidine kinase
HKBNCOEO_00100	1.31e-17	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HKBNCOEO_00101	1.9e-170	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKBNCOEO_00102	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKBNCOEO_00103	2.37e-181	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HKBNCOEO_00104	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKBNCOEO_00105	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKBNCOEO_00106	5.47e-314	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HKBNCOEO_00107	2.83e-175	-	-	-	-	-	-	-	-
HKBNCOEO_00108	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
HKBNCOEO_00109	8.49e-66	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00110	9.47e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKBNCOEO_00111	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKBNCOEO_00112	2.57e-274	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HKBNCOEO_00113	1.68e-277	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKBNCOEO_00115	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKBNCOEO_00116	6.94e-210	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HKBNCOEO_00117	7.26e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HKBNCOEO_00118	5.17e-162	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HKBNCOEO_00119	3.44e-216	-	-	-	-	-	-	-	-
HKBNCOEO_00120	3.28e-297	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKBNCOEO_00121	3.16e-82	-	-	-	K	-	-	-	Helix-turn-helix domain
HKBNCOEO_00122	9.2e-10	-	-	-	S	-	-	-	PIN domain
HKBNCOEO_00123	1.86e-59	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
HKBNCOEO_00124	7e-70	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
HKBNCOEO_00125	6.17e-97	-	-	-	P	-	-	-	branched-chain amino acid ABC transporter, permease protein
HKBNCOEO_00126	7.71e-144	-	-	-	G	-	-	-	ATPases associated with a variety of cellular activities
HKBNCOEO_00127	1.04e-97	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HKBNCOEO_00128	5.5e-211	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HKBNCOEO_00129	5.72e-90	xylR	-	-	GK	-	-	-	ROK family
HKBNCOEO_00130	2.37e-58	-	-	-	-	-	-	-	-
HKBNCOEO_00131	4.24e-217	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKBNCOEO_00132	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HKBNCOEO_00133	1.4e-192	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HKBNCOEO_00135	5.17e-126	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_00136	2.76e-162	-	-	-	-	-	-	-	-
HKBNCOEO_00137	7.22e-240	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKBNCOEO_00138	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKBNCOEO_00139	8.26e-106	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKBNCOEO_00140	6.66e-281	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKBNCOEO_00141	2.91e-278	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HKBNCOEO_00142	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKBNCOEO_00143	6.83e-132	-	-	-	-	-	-	-	-
HKBNCOEO_00144	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HKBNCOEO_00145	4.47e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKBNCOEO_00146	6.4e-241	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKBNCOEO_00147	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKBNCOEO_00148	1.74e-96	-	-	-	K	-	-	-	Transcriptional regulator
HKBNCOEO_00149	5.41e-253	-	-	-	S	-	-	-	Protein conserved in bacteria
HKBNCOEO_00150	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HKBNCOEO_00151	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HKBNCOEO_00152	1.58e-209	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKBNCOEO_00153	2.49e-265	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKBNCOEO_00154	5.97e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKBNCOEO_00156	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00157	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00158	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HKBNCOEO_00159	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HKBNCOEO_00160	1.15e-259	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
HKBNCOEO_00161	3.09e-224	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKBNCOEO_00162	2.47e-153	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_00163	3.31e-300	tcsS3	-	-	KT	-	-	-	PspC domain
HKBNCOEO_00164	0.0	pspC	-	-	KT	-	-	-	PspC domain
HKBNCOEO_00165	7.82e-105	-	-	-	-	-	-	-	-
HKBNCOEO_00166	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HKBNCOEO_00167	1.83e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HKBNCOEO_00168	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HKBNCOEO_00169	3.82e-276	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HKBNCOEO_00171	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKBNCOEO_00172	2.77e-222	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HKBNCOEO_00173	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKBNCOEO_00174	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKBNCOEO_00175	1.68e-234	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKBNCOEO_00176	2.3e-44	-	-	-	-	-	-	-	-
HKBNCOEO_00177	1.6e-268	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKBNCOEO_00178	2.08e-216	-	-	-	S	-	-	-	CHAP domain
HKBNCOEO_00179	1.3e-141	-	-	-	M	-	-	-	NlpC/P60 family
HKBNCOEO_00180	1.08e-142	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HKBNCOEO_00182	2.25e-240	-	-	-	T	-	-	-	Universal stress protein family
HKBNCOEO_00183	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
HKBNCOEO_00184	8.56e-215	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKBNCOEO_00185	1.2e-161	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HKBNCOEO_00186	3.01e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HKBNCOEO_00187	9.79e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_00188	5.09e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HKBNCOEO_00189	1.03e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKBNCOEO_00190	7.34e-12	-	-	-	L	-	-	-	HTH-like domain
HKBNCOEO_00191	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HKBNCOEO_00192	1.83e-278	-	-	-	GK	-	-	-	ROK family
HKBNCOEO_00193	3.96e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00194	5.83e-28	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_00195	2.07e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKBNCOEO_00196	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKBNCOEO_00198	1.72e-97	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_00199	1.27e-291	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HKBNCOEO_00200	4.3e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00201	1.81e-39	-	-	-	L	-	-	-	Transposase DDE domain
HKBNCOEO_00202	3.76e-17	-	-	-	L	-	-	-	Transposase DDE domain
HKBNCOEO_00203	2.34e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_00204	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKBNCOEO_00205	9.62e-116	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKBNCOEO_00206	3.56e-104	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKBNCOEO_00207	1.35e-94	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKBNCOEO_00208	2.07e-145	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HKBNCOEO_00211	5.1e-126	-	-	-	-	-	-	-	-
HKBNCOEO_00212	0.0	-	-	-	M	-	-	-	Conserved repeat domain
HKBNCOEO_00213	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HKBNCOEO_00215	3.09e-66	-	-	-	-	-	-	-	-
HKBNCOEO_00217	6.46e-145	-	-	-	-	-	-	-	-
HKBNCOEO_00218	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKBNCOEO_00219	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKBNCOEO_00220	4.3e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKBNCOEO_00221	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKBNCOEO_00222	1.21e-14	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKBNCOEO_00223	7.26e-72	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKBNCOEO_00224	1.67e-84	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKBNCOEO_00225	1.42e-28	-	-	-	-	-	-	-	-
HKBNCOEO_00226	2.87e-216	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HKBNCOEO_00227	3.03e-257	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKBNCOEO_00228	5.15e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKBNCOEO_00229	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKBNCOEO_00230	9.48e-85	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKBNCOEO_00231	2.08e-274	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HKBNCOEO_00232	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKBNCOEO_00233	2.72e-208	-	-	-	P	-	-	-	Cation efflux family
HKBNCOEO_00234	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKBNCOEO_00235	9.61e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HKBNCOEO_00236	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HKBNCOEO_00237	8.06e-96	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
HKBNCOEO_00238	1.52e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
HKBNCOEO_00239	4.76e-119	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HKBNCOEO_00240	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HKBNCOEO_00241	7.11e-172	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKBNCOEO_00242	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKBNCOEO_00243	3.89e-151	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKBNCOEO_00244	1.47e-155	-	-	-	-	-	-	-	-
HKBNCOEO_00245	5.54e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKBNCOEO_00246	4.23e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HKBNCOEO_00247	9.67e-251	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HKBNCOEO_00248	7.41e-102	-	-	-	K	-	-	-	MerR, DNA binding
HKBNCOEO_00249	5.52e-152	-	-	-	-	-	-	-	-
HKBNCOEO_00250	1.98e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKBNCOEO_00251	4.49e-185	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKBNCOEO_00252	2.55e-170	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKBNCOEO_00253	1.09e-225	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HKBNCOEO_00256	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKBNCOEO_00257	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00258	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00259	1.95e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKBNCOEO_00260	4.43e-221	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKBNCOEO_00261	2.34e-205	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKBNCOEO_00262	7.92e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_00263	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HKBNCOEO_00264	3.21e-66	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HKBNCOEO_00265	3.51e-11	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HKBNCOEO_00267	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HKBNCOEO_00268	6.35e-51	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HKBNCOEO_00269	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00270	1.94e-14	-	-	-	L	-	-	-	Transposase DDE domain
HKBNCOEO_00271	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HKBNCOEO_00272	7.28e-173	-	-	-	M	-	-	-	Mechanosensitive ion channel
HKBNCOEO_00273	8.39e-236	-	-	-	S	-	-	-	CAAX protease self-immunity
HKBNCOEO_00274	1.12e-303	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKBNCOEO_00275	3.37e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00276	4.85e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00277	3.04e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00278	7.06e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKBNCOEO_00279	1.38e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HKBNCOEO_00280	1.78e-241	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HKBNCOEO_00281	3.27e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HKBNCOEO_00284	3.19e-151	-	-	-	S	-	-	-	CYTH
HKBNCOEO_00285	5.98e-218	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HKBNCOEO_00286	3.14e-230	-	-	-	-	-	-	-	-
HKBNCOEO_00287	5.45e-243	-	-	-	-	-	-	-	-
HKBNCOEO_00288	2.43e-214	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HKBNCOEO_00289	1.23e-165	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HKBNCOEO_00290	3.62e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKBNCOEO_00291	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKBNCOEO_00292	1.2e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKBNCOEO_00293	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKBNCOEO_00294	4.31e-193	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKBNCOEO_00295	6.77e-99	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKBNCOEO_00296	1.42e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKBNCOEO_00297	1.33e-187	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKBNCOEO_00298	4.09e-262	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKBNCOEO_00300	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HKBNCOEO_00301	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HKBNCOEO_00302	9.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HKBNCOEO_00303	1.11e-125	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HKBNCOEO_00304	1.04e-153	-	-	-	-	-	-	-	-
HKBNCOEO_00305	2.67e-179	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HKBNCOEO_00306	8.09e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKBNCOEO_00307	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKBNCOEO_00308	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKBNCOEO_00309	0.0	-	-	-	S	-	-	-	domain protein
HKBNCOEO_00310	1.89e-82	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HKBNCOEO_00311	4.7e-62	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HKBNCOEO_00312	3.01e-46	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_00313	3.15e-27	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_00314	2.52e-157	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKBNCOEO_00315	1.09e-145	araQ	-	-	U	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00316	7.2e-159	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00317	4.35e-191	araN	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00318	1.25e-44	-	-	-	K	-	-	-	AraC-like ligand binding domain
HKBNCOEO_00319	1.42e-144	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKBNCOEO_00320	5.23e-59	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HKBNCOEO_00321	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKBNCOEO_00322	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HKBNCOEO_00323	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HKBNCOEO_00324	9.64e-248	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_00325	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKBNCOEO_00326	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKBNCOEO_00327	7.57e-68	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKBNCOEO_00328	3.05e-204	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_00329	5.99e-226	-	-	-	-	-	-	-	-
HKBNCOEO_00330	9.54e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKBNCOEO_00331	2.85e-215	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HKBNCOEO_00332	3.99e-141	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKBNCOEO_00333	2.18e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HKBNCOEO_00334	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HKBNCOEO_00335	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKBNCOEO_00336	2.45e-161	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKBNCOEO_00338	1.72e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKBNCOEO_00339	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKBNCOEO_00340	4.09e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HKBNCOEO_00341	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKBNCOEO_00342	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKBNCOEO_00343	3.91e-245	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_00344	2.6e-58	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_00345	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKBNCOEO_00346	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HKBNCOEO_00347	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HKBNCOEO_00348	5.09e-124	-	-	-	F	-	-	-	NUDIX domain
HKBNCOEO_00349	5.61e-311	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HKBNCOEO_00350	5.46e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKBNCOEO_00351	1.07e-264	-	-	-	GK	-	-	-	ROK family
HKBNCOEO_00352	2e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKBNCOEO_00354	6.67e-281	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKBNCOEO_00355	5.56e-215	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKBNCOEO_00356	8.35e-07	-	-	-	-	-	-	-	-
HKBNCOEO_00358	3.94e-229	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HKBNCOEO_00359	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKBNCOEO_00360	1.38e-275	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKBNCOEO_00361	2.45e-288	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HKBNCOEO_00362	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKBNCOEO_00363	1.58e-263	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKBNCOEO_00364	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKBNCOEO_00365	3.7e-200	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKBNCOEO_00366	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HKBNCOEO_00367	1.84e-90	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HKBNCOEO_00368	2.09e-243	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKBNCOEO_00369	2.33e-120	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKBNCOEO_00370	0.0	-	-	-	L	-	-	-	DNA helicase
HKBNCOEO_00371	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKBNCOEO_00372	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKBNCOEO_00373	1.43e-67	-	-	-	M	-	-	-	Lysin motif
HKBNCOEO_00374	4.82e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKBNCOEO_00375	1.39e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKBNCOEO_00376	2.67e-224	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKBNCOEO_00377	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKBNCOEO_00378	1.99e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HKBNCOEO_00379	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HKBNCOEO_00380	1.24e-279	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HKBNCOEO_00381	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKBNCOEO_00382	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HKBNCOEO_00383	5.86e-168	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HKBNCOEO_00384	3.43e-154	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKBNCOEO_00385	7.57e-163	-	-	-	-	-	-	-	-
HKBNCOEO_00386	1.66e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HKBNCOEO_00387	1.57e-279	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKBNCOEO_00388	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKBNCOEO_00389	4.18e-71	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
HKBNCOEO_00390	7.81e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
HKBNCOEO_00391	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HKBNCOEO_00392	7.85e-210	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HKBNCOEO_00394	1.39e-186	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HKBNCOEO_00395	1.18e-312	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HKBNCOEO_00396	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00397	5.59e-224	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00398	2.27e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00399	8.17e-109	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HKBNCOEO_00402	4.92e-18	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
HKBNCOEO_00403	1.59e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HKBNCOEO_00406	3.83e-17	-	-	-	-	-	-	-	-
HKBNCOEO_00407	5.77e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_00408	3.63e-274	-	-	-	G	-	-	-	Transmembrane secretion effector
HKBNCOEO_00409	1.76e-23	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
HKBNCOEO_00410	1.04e-307	-	-	-	S	-	-	-	HipA-like C-terminal domain
HKBNCOEO_00411	1.52e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKBNCOEO_00412	9.65e-143	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00413	2.26e-153	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00414	7.78e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HKBNCOEO_00415	4e-198	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKBNCOEO_00416	2.3e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKBNCOEO_00417	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HKBNCOEO_00418	0.0	-	-	-	T	-	-	-	Histidine kinase
HKBNCOEO_00419	1.18e-179	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_00420	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKBNCOEO_00421	2.44e-214	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_00422	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HKBNCOEO_00423	2.26e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKBNCOEO_00424	4.32e-29	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HKBNCOEO_00425	2.51e-98	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HKBNCOEO_00426	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HKBNCOEO_00427	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HKBNCOEO_00428	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HKBNCOEO_00429	4e-233	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HKBNCOEO_00430	1.88e-145	safC	-	-	S	-	-	-	O-methyltransferase
HKBNCOEO_00431	2.65e-214	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKBNCOEO_00432	5.35e-305	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HKBNCOEO_00433	2.41e-302	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HKBNCOEO_00436	9.18e-317	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKBNCOEO_00437	1.28e-155	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKBNCOEO_00438	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKBNCOEO_00439	1.85e-78	-	-	-	-	-	-	-	-
HKBNCOEO_00440	1.76e-312	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKBNCOEO_00441	3.47e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKBNCOEO_00442	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HKBNCOEO_00443	7.83e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HKBNCOEO_00444	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKBNCOEO_00445	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKBNCOEO_00446	1.24e-51	-	-	-	-	-	-	-	-
HKBNCOEO_00447	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKBNCOEO_00448	5.66e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
HKBNCOEO_00449	3.9e-146	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00450	6.93e-281	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKBNCOEO_00451	4.26e-224	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HKBNCOEO_00452	1.15e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKBNCOEO_00455	7.2e-174	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HKBNCOEO_00456	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKBNCOEO_00457	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKBNCOEO_00458	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HKBNCOEO_00459	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKBNCOEO_00460	3.48e-23	-	-	-	-	-	-	-	-
HKBNCOEO_00461	5.21e-09	-	-	-	-	-	-	-	-
HKBNCOEO_00462	3.59e-38	-	-	-	-	-	-	-	-
HKBNCOEO_00463	4.79e-69	-	-	-	S	-	-	-	Putative DNA-binding domain
HKBNCOEO_00464	3.2e-138	-	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HKBNCOEO_00466	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HKBNCOEO_00467	1.08e-214	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
HKBNCOEO_00469	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HKBNCOEO_00470	1.01e-254	-	-	-	K	-	-	-	WYL domain
HKBNCOEO_00471	4.29e-227	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKBNCOEO_00472	2.45e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKBNCOEO_00473	2.85e-105	-	-	-	V	-	-	-	DivIVA protein
HKBNCOEO_00474	3.44e-60	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKBNCOEO_00475	1.42e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKBNCOEO_00476	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKBNCOEO_00477	2.02e-316	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKBNCOEO_00478	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HKBNCOEO_00479	1.05e-202	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKBNCOEO_00480	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKBNCOEO_00481	4.39e-287	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
HKBNCOEO_00482	6.57e-182	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKBNCOEO_00483	9.51e-81	-	-	-	S	-	-	-	Thiamine-binding protein
HKBNCOEO_00484	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HKBNCOEO_00485	1.18e-293	-	-	-	T	-	-	-	Histidine kinase
HKBNCOEO_00486	5.01e-159	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_00487	8.19e-244	-	-	-	-	-	-	-	-
HKBNCOEO_00488	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
HKBNCOEO_00489	8.6e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_00490	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HKBNCOEO_00491	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HKBNCOEO_00492	6.61e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKBNCOEO_00493	8.77e-193	-	-	-	C	-	-	-	Putative TM nitroreductase
HKBNCOEO_00494	1.55e-252	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HKBNCOEO_00495	4.04e-134	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKBNCOEO_00496	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_00497	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HKBNCOEO_00498	1.66e-70	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKBNCOEO_00499	2.26e-67	-	-	-	-	-	-	-	-
HKBNCOEO_00500	5.73e-239	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKBNCOEO_00501	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00502	1.53e-41	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKBNCOEO_00503	2.53e-14	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKBNCOEO_00504	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HKBNCOEO_00505	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HKBNCOEO_00506	8.51e-254	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKBNCOEO_00507	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HKBNCOEO_00508	6.56e-145	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HKBNCOEO_00509	0.0	-	-	-	I	-	-	-	PAP2 superfamily
HKBNCOEO_00510	1.27e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00511	2.44e-143	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00512	3.54e-186	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKBNCOEO_00513	6.38e-196	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HKBNCOEO_00514	5.22e-131	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HKBNCOEO_00515	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKBNCOEO_00516	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HKBNCOEO_00517	0.0	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HKBNCOEO_00518	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HKBNCOEO_00519	4.49e-182	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
HKBNCOEO_00520	0.0	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HKBNCOEO_00522	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
HKBNCOEO_00523	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HKBNCOEO_00524	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HKBNCOEO_00525	2.31e-230	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKBNCOEO_00526	7.53e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HKBNCOEO_00527	1.75e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKBNCOEO_00528	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKBNCOEO_00529	2.48e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HKBNCOEO_00530	2.67e-148	-	-	-	-	-	-	-	-
HKBNCOEO_00531	6.57e-54	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HKBNCOEO_00532	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKBNCOEO_00533	1.54e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKBNCOEO_00534	8.33e-127	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HKBNCOEO_00535	8.09e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKBNCOEO_00536	1.53e-245	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKBNCOEO_00537	3.97e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKBNCOEO_00538	2.68e-118	-	-	-	-	-	-	-	-
HKBNCOEO_00539	7.54e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HKBNCOEO_00540	4.24e-213	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HKBNCOEO_00541	8.64e-76	-	-	-	-	-	-	-	-
HKBNCOEO_00542	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HKBNCOEO_00543	2.13e-143	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKBNCOEO_00544	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HKBNCOEO_00545	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HKBNCOEO_00546	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HKBNCOEO_00547	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HKBNCOEO_00548	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HKBNCOEO_00549	4.8e-224	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HKBNCOEO_00550	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HKBNCOEO_00551	4.32e-173	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
HKBNCOEO_00552	4.16e-229	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HKBNCOEO_00553	2.2e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKBNCOEO_00554	5.44e-104	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKBNCOEO_00555	3.14e-94	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKBNCOEO_00556	0.0	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
HKBNCOEO_00557	4.48e-170	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKBNCOEO_00558	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HKBNCOEO_00559	3.4e-162	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKBNCOEO_00560	3.93e-152	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HKBNCOEO_00561	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKBNCOEO_00562	8.38e-169	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKBNCOEO_00563	1.51e-234	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKBNCOEO_00564	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HKBNCOEO_00565	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKBNCOEO_00566	1.67e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKBNCOEO_00567	4.94e-211	-	-	-	G	-	-	-	Fic/DOC family
HKBNCOEO_00568	2.3e-62	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HKBNCOEO_00569	4.78e-110	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKBNCOEO_00570	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HKBNCOEO_00571	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HKBNCOEO_00572	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HKBNCOEO_00573	1.01e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00574	2.78e-222	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00575	7.2e-200	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00576	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKBNCOEO_00577	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HKBNCOEO_00578	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HKBNCOEO_00579	2.45e-262	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_00580	5.35e-311	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HKBNCOEO_00581	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HKBNCOEO_00582	8.47e-42	-	-	-	-	-	-	-	-
HKBNCOEO_00583	4.85e-167	-	-	-	C	-	-	-	Putative TM nitroreductase
HKBNCOEO_00584	1.12e-216	-	-	-	EG	-	-	-	EamA-like transporter family
HKBNCOEO_00585	2.35e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HKBNCOEO_00586	4.05e-294	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HKBNCOEO_00587	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HKBNCOEO_00588	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKBNCOEO_00589	6.18e-205	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKBNCOEO_00590	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKBNCOEO_00591	9.69e-143	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HKBNCOEO_00592	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HKBNCOEO_00593	2.06e-220	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKBNCOEO_00594	8.71e-112	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HKBNCOEO_00595	1.39e-201	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HKBNCOEO_00596	3.32e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HKBNCOEO_00597	1.32e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKBNCOEO_00599	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKBNCOEO_00600	1.33e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKBNCOEO_00601	1.4e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_00602	2.26e-176	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
HKBNCOEO_00603	2.79e-180	-	-	-	S	-	-	-	Fic/DOC family
HKBNCOEO_00606	5.3e-08	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_00608	5.53e-17	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
HKBNCOEO_00609	1.11e-24	-	-	-	L	ko:K07484	-	ko00000	Belongs to the 'phage' integrase family
HKBNCOEO_00610	1.48e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKBNCOEO_00611	5.62e-226	-	-	-	V	-	-	-	Abi-like protein
HKBNCOEO_00612	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HKBNCOEO_00613	1.37e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKBNCOEO_00615	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HKBNCOEO_00616	1.89e-294	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKBNCOEO_00617	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKBNCOEO_00618	3.26e-274	-	-	-	-	-	-	-	-
HKBNCOEO_00620	2.57e-27	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HKBNCOEO_00622	2.24e-155	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKBNCOEO_00623	3.52e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
HKBNCOEO_00624	9.31e-36	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKBNCOEO_00625	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKBNCOEO_00626	4.87e-163	-	-	-	L	-	-	-	NUDIX domain
HKBNCOEO_00627	4.64e-227	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HKBNCOEO_00628	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKBNCOEO_00629	2.41e-166	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HKBNCOEO_00631	1.59e-138	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKBNCOEO_00632	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HKBNCOEO_00633	3.81e-228	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HKBNCOEO_00634	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKBNCOEO_00635	1.18e-134	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKBNCOEO_00636	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKBNCOEO_00637	3.6e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKBNCOEO_00638	7.52e-264	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKBNCOEO_00639	1.5e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00640	1.1e-174	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HKBNCOEO_00641	1.77e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKBNCOEO_00642	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HKBNCOEO_00643	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKBNCOEO_00644	3.51e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HKBNCOEO_00645	4.09e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKBNCOEO_00646	5.28e-158	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HKBNCOEO_00647	2.92e-190	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HKBNCOEO_00648	2.13e-101	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HKBNCOEO_00649	0.0	-	-	-	-	-	-	-	-
HKBNCOEO_00650	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HKBNCOEO_00651	2.06e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HKBNCOEO_00652	2.54e-303	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HKBNCOEO_00653	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HKBNCOEO_00654	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HKBNCOEO_00655	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKBNCOEO_00656	9.75e-192	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HKBNCOEO_00657	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKBNCOEO_00658	8.17e-98	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HKBNCOEO_00659	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HKBNCOEO_00660	2.34e-121	-	-	-	-	-	-	-	-
HKBNCOEO_00661	6.99e-50	int8	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_00662	8.98e-109	int8	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_00668	2.33e-44	-	-	-	-	-	-	-	-
HKBNCOEO_00669	2.07e-11	-	-	-	-	-	-	-	-
HKBNCOEO_00670	2.76e-149	-	-	-	K	-	-	-	Fic/DOC family
HKBNCOEO_00671	2.64e-08	-	-	-	-	-	-	-	-
HKBNCOEO_00672	1.1e-34	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_00673	2.65e-59	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_00674	7.81e-187	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_00675	6.48e-300	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HKBNCOEO_00676	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
HKBNCOEO_00677	3.03e-165	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
HKBNCOEO_00678	3.86e-161	-	-	-	P	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00679	5.11e-267	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00680	7.8e-115	-	-	-	L	-	-	-	Resolvase, N terminal domain
HKBNCOEO_00681	1.22e-59	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_00682	1.05e-102	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HKBNCOEO_00683	5.87e-102	-	-	-	L	-	-	-	HTH-like domain
HKBNCOEO_00685	9.07e-234	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HKBNCOEO_00686	2.77e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HKBNCOEO_00687	1.51e-103	-	-	-	D	-	-	-	Septum formation initiator
HKBNCOEO_00688	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKBNCOEO_00689	1.82e-227	-	-	-	C	-	-	-	Aldo/keto reductase family
HKBNCOEO_00690	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKBNCOEO_00691	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKBNCOEO_00692	7.51e-118	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKBNCOEO_00693	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HKBNCOEO_00695	2.65e-194	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKBNCOEO_00697	3.76e-213	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HKBNCOEO_00698	1.15e-164	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
HKBNCOEO_00699	5.25e-176	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKBNCOEO_00700	1.26e-124	-	-	-	-	-	-	-	-
HKBNCOEO_00701	4.49e-298	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKBNCOEO_00702	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HKBNCOEO_00703	1.36e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKBNCOEO_00704	1.07e-93	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKBNCOEO_00705	3.61e-37	pacL2	3.6.3.8	-	P	ko:K01537,ko:K12955	-	ko00000,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HKBNCOEO_00706	4.04e-125	-	-	-	S	-	-	-	ABC-2 family transporter protein
HKBNCOEO_00707	1.94e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
HKBNCOEO_00708	1.32e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00709	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKBNCOEO_00710	1.32e-23	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_00711	1.37e-17	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_00712	1.34e-151	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKBNCOEO_00713	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKBNCOEO_00714	9.09e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKBNCOEO_00715	4.29e-50	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HKBNCOEO_00716	1.25e-64	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HKBNCOEO_00717	7.68e-151	-	-	-	-	-	-	-	-
HKBNCOEO_00718	1.28e-179	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKBNCOEO_00720	2.4e-257	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HKBNCOEO_00721	7.66e-308	-	-	-	L	-	-	-	Tetratricopeptide repeat
HKBNCOEO_00722	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKBNCOEO_00723	2.29e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKBNCOEO_00724	9.39e-181	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HKBNCOEO_00725	6.92e-133	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKBNCOEO_00726	5.26e-84	-	-	-	P	-	-	-	Rhodanese Homology Domain
HKBNCOEO_00727	1.62e-188	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HKBNCOEO_00728	1.19e-200	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKBNCOEO_00729	5.91e-38	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HKBNCOEO_00730	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKBNCOEO_00731	1.2e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKBNCOEO_00732	1.24e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKBNCOEO_00733	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKBNCOEO_00734	1.39e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKBNCOEO_00735	6.84e-226	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKBNCOEO_00736	9.26e-270	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKBNCOEO_00737	5.47e-258	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKBNCOEO_00738	5.13e-137	-	-	-	-	-	-	-	-
HKBNCOEO_00739	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HKBNCOEO_00740	5.07e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKBNCOEO_00741	8.12e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKBNCOEO_00742	1.45e-208	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKBNCOEO_00743	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00744	4.38e-140	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKBNCOEO_00745	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HKBNCOEO_00746	1.8e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HKBNCOEO_00747	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKBNCOEO_00748	2.29e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HKBNCOEO_00749	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKBNCOEO_00750	3.04e-259	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKBNCOEO_00751	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKBNCOEO_00752	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKBNCOEO_00753	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKBNCOEO_00754	3.54e-22	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HKBNCOEO_00755	3.12e-179	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00756	2.74e-284	-	-	-	E	-	-	-	Aminotransferase class I and II
HKBNCOEO_00757	2.17e-243	-	-	-	P	-	-	-	NMT1/THI5 like
HKBNCOEO_00758	8.22e-172	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00759	1.58e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKBNCOEO_00760	4.62e-164	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKBNCOEO_00761	0.0	-	-	-	I	-	-	-	acetylesterase activity
HKBNCOEO_00762	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKBNCOEO_00763	4.35e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKBNCOEO_00764	2.12e-295	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HKBNCOEO_00766	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HKBNCOEO_00767	3.66e-211	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKBNCOEO_00768	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HKBNCOEO_00769	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKBNCOEO_00770	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HKBNCOEO_00771	3.25e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HKBNCOEO_00772	1.54e-216	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HKBNCOEO_00773	2.39e-166	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HKBNCOEO_00774	9.28e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HKBNCOEO_00775	4.68e-190	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKBNCOEO_00776	5.74e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
HKBNCOEO_00777	1.74e-72	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_00778	1.79e-170	hflK	-	-	O	-	-	-	prohibitin homologues
HKBNCOEO_00779	1.41e-11	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKBNCOEO_00780	3.8e-56	-	-	-	O	-	-	-	Glutaredoxin
HKBNCOEO_00781	1.83e-297	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKBNCOEO_00782	1.2e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HKBNCOEO_00783	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HKBNCOEO_00784	1.98e-06	-	-	-	-	-	-	-	-
HKBNCOEO_00785	7.2e-175	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HKBNCOEO_00786	2.64e-135	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKBNCOEO_00787	4.4e-216	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKBNCOEO_00788	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKBNCOEO_00789	2.95e-306	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HKBNCOEO_00790	1.45e-120	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKBNCOEO_00791	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKBNCOEO_00792	1.23e-162	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00793	2.46e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKBNCOEO_00794	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HKBNCOEO_00795	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
HKBNCOEO_00796	0.0	-	-	-	M	-	-	-	probably involved in cell wall
HKBNCOEO_00798	4.23e-63	-	4.1.1.44	-	L	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HKBNCOEO_00799	3.4e-236	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKBNCOEO_00800	2.75e-52	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKBNCOEO_00801	3.5e-149	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKBNCOEO_00802	0.000207	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKBNCOEO_00803	1.22e-156	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
HKBNCOEO_00804	8.03e-311	-	-	-	V	-	-	-	MatE
HKBNCOEO_00805	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKBNCOEO_00806	1.33e-176	-	-	-	K	-	-	-	LysR substrate binding domain
HKBNCOEO_00807	4.37e-283	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00808	2.56e-197	-	-	-	K	-	-	-	LysR substrate binding domain
HKBNCOEO_00809	9.67e-274	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HKBNCOEO_00811	1.5e-180	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_00812	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
HKBNCOEO_00813	4.88e-176	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKBNCOEO_00814	2.96e-173	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKBNCOEO_00815	3.01e-197	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00816	1.79e-222	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00817	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKBNCOEO_00818	1.06e-297	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HKBNCOEO_00819	6.01e-186	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKBNCOEO_00820	8.35e-212	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HKBNCOEO_00821	2.38e-99	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HKBNCOEO_00822	1.52e-45	-	-	-	-	-	-	-	-
HKBNCOEO_00823	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_00824	5.61e-251	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HKBNCOEO_00825	1.06e-97	-	-	-	K	-	-	-	MerR family regulatory protein
HKBNCOEO_00826	2.12e-114	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKBNCOEO_00827	1.37e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKBNCOEO_00828	2.16e-40	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKBNCOEO_00830	1.02e-236	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKBNCOEO_00831	4.28e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKBNCOEO_00832	1.04e-164	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HKBNCOEO_00833	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKBNCOEO_00834	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKBNCOEO_00835	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKBNCOEO_00836	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKBNCOEO_00837	3.25e-142	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HKBNCOEO_00839	1.01e-250	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HKBNCOEO_00840	6.11e-277	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HKBNCOEO_00841	1.56e-110	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKBNCOEO_00842	2.09e-18	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKBNCOEO_00843	4.64e-165	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HKBNCOEO_00844	2.78e-82	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKBNCOEO_00846	4.76e-305	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKBNCOEO_00847	4.41e-137	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HKBNCOEO_00848	5.13e-209	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKBNCOEO_00849	4.87e-298	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HKBNCOEO_00850	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HKBNCOEO_00851	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKBNCOEO_00852	1.78e-241	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HKBNCOEO_00853	7.51e-145	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HKBNCOEO_00854	1.38e-145	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_00855	4.53e-274	-	-	-	T	-	-	-	Histidine kinase
HKBNCOEO_00856	1.01e-13	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKBNCOEO_00857	6.27e-224	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00858	5.48e-281	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKBNCOEO_00859	2.84e-304	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKBNCOEO_00860	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HKBNCOEO_00861	2.69e-62	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKBNCOEO_00862	6.11e-262	-	-	-	-	-	-	-	-
HKBNCOEO_00863	4.17e-142	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HKBNCOEO_00864	2.51e-137	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HKBNCOEO_00865	3.78e-219	-	-	-	M	-	-	-	pfam nlp p60
HKBNCOEO_00866	3.68e-195	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HKBNCOEO_00867	4.02e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HKBNCOEO_00868	2.88e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HKBNCOEO_00869	1.48e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKBNCOEO_00870	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKBNCOEO_00871	4.61e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HKBNCOEO_00872	1.28e-274	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKBNCOEO_00873	3.15e-203	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKBNCOEO_00874	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKBNCOEO_00875	1.07e-193	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HKBNCOEO_00876	1.54e-90	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
HKBNCOEO_00877	1.01e-65	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKBNCOEO_00878	1.03e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HKBNCOEO_00879	6.1e-85	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKBNCOEO_00880	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKBNCOEO_00881	2.43e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HKBNCOEO_00882	1.28e-76	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HKBNCOEO_00883	6.59e-48	-	-	-	-	-	-	-	-
HKBNCOEO_00884	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKBNCOEO_00885	2.12e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKBNCOEO_00886	2.97e-252	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKBNCOEO_00887	1.74e-91	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HKBNCOEO_00888	1.01e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKBNCOEO_00889	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKBNCOEO_00890	2.01e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HKBNCOEO_00891	1.24e-120	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_00892	4.21e-31	-	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_00894	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
HKBNCOEO_00895	1.2e-262	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HKBNCOEO_00896	0.0	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HKBNCOEO_00897	0.0	-	2.1.1.72	-	L	ko:K07317	-	ko00000,ko01000,ko02048	Eco57I restriction-modification methylase
HKBNCOEO_00898	3.7e-233	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	BsuBI/PstI restriction endonuclease C-terminus
HKBNCOEO_00899	9.61e-287	-	-	-	-	-	-	-	-
HKBNCOEO_00901	6.83e-89	-	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_00902	5.25e-107	-	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_00903	9.48e-47	-	-	-	M	-	-	-	Peptidase family M23
HKBNCOEO_00904	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HKBNCOEO_00905	9.53e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HKBNCOEO_00906	4.18e-262	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HKBNCOEO_00907	5.83e-120	-	-	-	-	-	-	-	-
HKBNCOEO_00908	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HKBNCOEO_00909	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKBNCOEO_00910	1.56e-191	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKBNCOEO_00911	3.6e-183	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKBNCOEO_00912	1.09e-170	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKBNCOEO_00913	7.06e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKBNCOEO_00914	6.76e-222	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HKBNCOEO_00915	1.85e-284	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKBNCOEO_00916	7.48e-68	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKBNCOEO_00917	4.75e-21	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKBNCOEO_00918	1.18e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKBNCOEO_00919	1.32e-92	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKBNCOEO_00920	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKBNCOEO_00921	5.46e-118	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HKBNCOEO_00922	3.58e-206	-	-	-	-	-	-	-	-
HKBNCOEO_00923	2.3e-96	-	-	-	-	-	-	-	-
HKBNCOEO_00924	5.5e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HKBNCOEO_00925	5.32e-11	-	-	-	-	-	-	-	-
HKBNCOEO_00926	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HKBNCOEO_00927	1.77e-27	-	-	-	G	-	-	-	Major facilitator Superfamily
HKBNCOEO_00928	2.68e-54	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00929	8.55e-120	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HKBNCOEO_00930	2.25e-150	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
HKBNCOEO_00931	7.15e-43	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HKBNCOEO_00932	4.3e-120	-	-	-	-	-	-	-	-
HKBNCOEO_00935	3.17e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_00936	2.58e-167	-	-	-	-	-	-	-	-
HKBNCOEO_00937	8.32e-133	-	-	-	-	-	-	-	-
HKBNCOEO_00938	4.12e-178	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HKBNCOEO_00939	1.68e-51	-	-	-	-	-	-	-	-
HKBNCOEO_00940	8.76e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HKBNCOEO_00941	8.31e-115	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_00942	1.64e-119	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_00943	4.54e-83	-	2.7.13.3	-	T	ko:K07675	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKBNCOEO_00944	7.78e-71	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKBNCOEO_00945	6.37e-125	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HKBNCOEO_00946	2.36e-90	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKBNCOEO_00947	8.1e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKBNCOEO_00948	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKBNCOEO_00949	2e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKBNCOEO_00950	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKBNCOEO_00951	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKBNCOEO_00952	1.05e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKBNCOEO_00953	5.04e-315	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKBNCOEO_00954	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HKBNCOEO_00955	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HKBNCOEO_00956	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKBNCOEO_00957	3.09e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKBNCOEO_00958	5.43e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKBNCOEO_00959	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKBNCOEO_00960	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKBNCOEO_00961	3.93e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKBNCOEO_00962	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKBNCOEO_00963	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKBNCOEO_00964	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKBNCOEO_00965	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKBNCOEO_00966	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKBNCOEO_00967	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKBNCOEO_00968	1.09e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKBNCOEO_00969	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKBNCOEO_00970	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKBNCOEO_00971	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKBNCOEO_00972	9.78e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKBNCOEO_00973	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKBNCOEO_00974	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKBNCOEO_00975	3.82e-176	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HKBNCOEO_00976	7.26e-185	-	-	-	S	-	-	-	YwiC-like protein
HKBNCOEO_00977	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKBNCOEO_00978	2.64e-217	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKBNCOEO_00979	6.49e-245	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HKBNCOEO_00980	1.73e-248	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00981	2.69e-272	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HKBNCOEO_00982	2.66e-97	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKBNCOEO_00983	3.04e-296	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_00984	2.47e-227	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HKBNCOEO_00985	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKBNCOEO_00986	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKBNCOEO_00987	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKBNCOEO_00988	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKBNCOEO_00989	9.47e-152	-	-	-	-	-	-	-	-
HKBNCOEO_00990	9.37e-142	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HKBNCOEO_00991	6.76e-233	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKBNCOEO_00992	3.07e-19	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HKBNCOEO_00993	2.49e-47	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HKBNCOEO_00994	2.08e-131	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_00995	4.98e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HKBNCOEO_00996	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKBNCOEO_00997	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00998	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_00999	1.29e-183	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKBNCOEO_01000	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKBNCOEO_01001	1.57e-214	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01002	4.22e-193	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01003	6.51e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HKBNCOEO_01004	1.6e-175	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01005	8.21e-245	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKBNCOEO_01006	1.02e-279	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKBNCOEO_01007	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKBNCOEO_01008	4.78e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKBNCOEO_01009	4.31e-133	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKBNCOEO_01010	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HKBNCOEO_01011	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKBNCOEO_01012	1.14e-307	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HKBNCOEO_01013	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKBNCOEO_01014	8.7e-91	-	-	-	S	-	-	-	PIN domain
HKBNCOEO_01015	1.15e-47	-	-	-	-	-	-	-	-
HKBNCOEO_01016	1.63e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKBNCOEO_01017	1.2e-148	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKBNCOEO_01018	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
HKBNCOEO_01019	9.59e-268	-	-	-	P	-	-	-	Citrate transporter
HKBNCOEO_01020	9.8e-41	-	-	-	-	-	-	-	-
HKBNCOEO_01021	2.24e-50	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HKBNCOEO_01022	2.93e-201	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKBNCOEO_01025	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01026	9.75e-295	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_01027	1.43e-63	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
HKBNCOEO_01028	1.44e-42	-	-	-	-	-	-	-	-
HKBNCOEO_01029	7.33e-183	-	-	-	-	-	-	-	-
HKBNCOEO_01030	1.64e-86	-	-	-	S	-	-	-	PrgI family protein
HKBNCOEO_01031	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
HKBNCOEO_01032	0.0	-	-	-	M	-	-	-	CHAP domain
HKBNCOEO_01033	8.71e-242	-	-	-	-	-	-	-	-
HKBNCOEO_01035	5.72e-83	-	-	-	S	-	-	-	Putative amidase domain
HKBNCOEO_01036	1.82e-126	-	-	-	S	-	-	-	Putative amidase domain
HKBNCOEO_01037	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
HKBNCOEO_01038	7.51e-78	-	-	-	-	-	-	-	-
HKBNCOEO_01039	4.83e-61	-	-	-	-	-	-	-	-
HKBNCOEO_01040	5.89e-161	-	-	-	-	-	-	-	-
HKBNCOEO_01041	0.0	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HKBNCOEO_01042	4.93e-220	-	-	-	-	-	-	-	-
HKBNCOEO_01043	2.72e-207	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HKBNCOEO_01044	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HKBNCOEO_01045	2.35e-92	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HKBNCOEO_01046	1.85e-110	-	-	-	-	-	-	-	-
HKBNCOEO_01047	2.58e-62	-	-	-	-	-	-	-	-
HKBNCOEO_01048	0.0	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HKBNCOEO_01049	1.15e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF4192)
HKBNCOEO_01050	1.45e-296	-	-	-	T	-	-	-	Histidine kinase
HKBNCOEO_01051	1.55e-160	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_01052	2.21e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKBNCOEO_01053	1.06e-24	-	-	-	-	-	-	-	-
HKBNCOEO_01054	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKBNCOEO_01055	2.87e-42	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKBNCOEO_01056	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKBNCOEO_01058	9.4e-187	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Thiopeptide-type bacteriocin biosynthesis domain protein
HKBNCOEO_01059	1.44e-131	-	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Psort location Cytoplasmic, score
HKBNCOEO_01061	3.22e-146	-	-	-	V	-	-	-	VanZ like family
HKBNCOEO_01062	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HKBNCOEO_01063	1.51e-206	-	-	-	-	-	-	-	-
HKBNCOEO_01064	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HKBNCOEO_01065	3.7e-19	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HKBNCOEO_01066	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HKBNCOEO_01067	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HKBNCOEO_01068	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HKBNCOEO_01069	1.63e-195	-	-	-	P	-	-	-	VTC domain
HKBNCOEO_01070	4.71e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HKBNCOEO_01071	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HKBNCOEO_01072	1.27e-118	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HKBNCOEO_01073	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HKBNCOEO_01074	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKBNCOEO_01075	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKBNCOEO_01076	1.57e-53	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKBNCOEO_01077	4.81e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
HKBNCOEO_01078	0.0	-	-	-	S	-	-	-	Amidohydrolase family
HKBNCOEO_01079	5.93e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKBNCOEO_01080	2.08e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HKBNCOEO_01081	4.6e-147	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKBNCOEO_01082	6.47e-266	-	-	-	T	-	-	-	Histidine kinase
HKBNCOEO_01083	8.23e-294	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_01084	2.13e-94	-	-	-	I	-	-	-	Sterol carrier protein
HKBNCOEO_01086	6.66e-298	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKBNCOEO_01087	1.14e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKBNCOEO_01088	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HKBNCOEO_01089	8.75e-298	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKBNCOEO_01090	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HKBNCOEO_01091	3.12e-143	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HKBNCOEO_01092	1.96e-131	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HKBNCOEO_01093	1.95e-19	-	-	-	C	-	-	-	Aldo/keto reductase family
HKBNCOEO_01094	1.63e-43	-	-	-	-	-	-	-	-
HKBNCOEO_01095	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HKBNCOEO_01096	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKBNCOEO_01097	6.44e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKBNCOEO_01098	7.04e-308	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKBNCOEO_01099	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HKBNCOEO_01100	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HKBNCOEO_01101	7.06e-198	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKBNCOEO_01102	6.55e-93	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKBNCOEO_01103	3.18e-282	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKBNCOEO_01104	3.44e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKBNCOEO_01105	3.27e-230	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKBNCOEO_01106	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKBNCOEO_01107	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKBNCOEO_01108	3.69e-248	-	-	-	M	-	-	-	Conserved repeat domain
HKBNCOEO_01109	1.54e-182	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01110	1.78e-241	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HKBNCOEO_01111	1.75e-117	-	-	-	K	-	-	-	MarR family
HKBNCOEO_01112	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_01113	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKBNCOEO_01114	1.69e-171	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_01115	6.44e-177	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKBNCOEO_01116	8.7e-214	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HKBNCOEO_01117	7.24e-185	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKBNCOEO_01118	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKBNCOEO_01119	1e-76	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKBNCOEO_01120	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
HKBNCOEO_01121	9.86e-177	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HKBNCOEO_01122	0.0	-	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
HKBNCOEO_01123	5.28e-201	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HKBNCOEO_01124	3.43e-170	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
HKBNCOEO_01125	5.83e-251	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKBNCOEO_01126	1.65e-48	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKBNCOEO_01129	3.28e-36	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HKBNCOEO_01130	8.13e-18	-	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_01131	8.73e-35	-	-	-	S	-	-	-	PIN domain
HKBNCOEO_01132	2.32e-58	-	-	-	S	-	-	-	Helix-turn-helix domain
HKBNCOEO_01133	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
HKBNCOEO_01134	2.32e-152	-	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HKBNCOEO_01135	2.17e-122	-	-	-	K	-	-	-	FR47-like protein
HKBNCOEO_01136	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
HKBNCOEO_01137	7.39e-54	-	-	-	-	-	-	-	-
HKBNCOEO_01138	3.57e-130	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HKBNCOEO_01139	1.47e-111	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
HKBNCOEO_01140	6.06e-274	-	-	-	S	-	-	-	Helix-turn-helix domain
HKBNCOEO_01141	1.19e-15	-	-	-	S	-	-	-	Helix-turn-helix domain
HKBNCOEO_01143	1.49e-88	-	-	-	-	-	-	-	-
HKBNCOEO_01144	4.32e-298	intA	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_01145	1.55e-103	-	-	-	-	-	-	-	-
HKBNCOEO_01146	4.61e-167	-	-	-	-	-	-	-	-
HKBNCOEO_01149	6.67e-311	intA	-	-	L	-	-	-	Phage integrase family
HKBNCOEO_01150	1.78e-43	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HKBNCOEO_01151	7.61e-72	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HKBNCOEO_01152	3.67e-172	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HKBNCOEO_01153	1.23e-35	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HKBNCOEO_01155	8.73e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01156	3.3e-138	-	-	-	-	-	-	-	-
HKBNCOEO_01157	2.76e-104	-	-	-	-	-	-	-	-
HKBNCOEO_01160	5.75e-50	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
HKBNCOEO_01161	2.3e-56	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	PFAM ABC-2 type transporter
HKBNCOEO_01162	0.0	-	-	-	M	-	-	-	Cell surface antigen C-terminus
HKBNCOEO_01164	6.52e-157	-	-	-	K	-	-	-	Helix-turn-helix domain protein
HKBNCOEO_01165	4.56e-32	-	-	-	-	-	-	-	-
HKBNCOEO_01166	1.03e-91	-	-	-	-	-	-	-	-
HKBNCOEO_01167	1.43e-47	-	-	-	-	-	-	-	-
HKBNCOEO_01168	5.1e-134	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HKBNCOEO_01169	3.71e-127	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
HKBNCOEO_01170	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKBNCOEO_01171	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKBNCOEO_01172	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HKBNCOEO_01173	1.24e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HKBNCOEO_01174	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKBNCOEO_01175	1.25e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKBNCOEO_01176	4.82e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKBNCOEO_01177	2.19e-142	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKBNCOEO_01178	3.09e-307	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKBNCOEO_01179	7.89e-212	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HKBNCOEO_01181	1.21e-192	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKBNCOEO_01182	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HKBNCOEO_01183	3.27e-276	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HKBNCOEO_01184	1.33e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKBNCOEO_01185	0.0	corC	-	-	S	-	-	-	CBS domain
HKBNCOEO_01186	9.08e-235	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKBNCOEO_01187	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HKBNCOEO_01188	1.34e-260	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HKBNCOEO_01189	3.42e-56	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HKBNCOEO_01190	8.58e-308	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HKBNCOEO_01191	5.08e-299	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HKBNCOEO_01192	1.08e-129	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKBNCOEO_01193	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HKBNCOEO_01194	2.95e-187	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01195	4.82e-179	-	-	-	S	-	-	-	UPF0126 domain
HKBNCOEO_01196	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKBNCOEO_01197	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKBNCOEO_01198	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HKBNCOEO_01200	9.59e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_01201	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HKBNCOEO_01202	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKBNCOEO_01204	2.86e-58	-	-	-	-	-	-	-	-
HKBNCOEO_01205	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKBNCOEO_01206	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
HKBNCOEO_01207	2.41e-106	-	-	-	-	-	-	-	-
HKBNCOEO_01208	1.6e-310	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HKBNCOEO_01209	4.18e-202	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01210	3.18e-201	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKBNCOEO_01211	5.35e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HKBNCOEO_01212	4.24e-182	-	-	-	-	-	-	-	-
HKBNCOEO_01213	1.89e-101	-	-	-	L	-	-	-	Transposase, Mutator family
HKBNCOEO_01216	2.39e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKBNCOEO_01217	1.93e-117	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HKBNCOEO_01218	1.64e-186	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HKBNCOEO_01219	4.16e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKBNCOEO_01221	4.32e-172	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HKBNCOEO_01222	9.33e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HKBNCOEO_01223	5.84e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HKBNCOEO_01225	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKBNCOEO_01226	2.74e-208	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HKBNCOEO_01227	3.45e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKBNCOEO_01228	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HKBNCOEO_01229	8.56e-227	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKBNCOEO_01230	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HKBNCOEO_01231	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKBNCOEO_01232	1.74e-223	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HKBNCOEO_01233	2.25e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HKBNCOEO_01234	6.9e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKBNCOEO_01235	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKBNCOEO_01236	1.08e-39	-	-	-	-	-	-	-	-
HKBNCOEO_01237	4.99e-274	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01238	1.55e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKBNCOEO_01239	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKBNCOEO_01240	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKBNCOEO_01241	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKBNCOEO_01242	5.24e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKBNCOEO_01243	1.66e-25	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01244	4.45e-120	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
HKBNCOEO_01245	1.67e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01246	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKBNCOEO_01247	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKBNCOEO_01248	2.95e-240	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HKBNCOEO_01249	5.43e-229	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKBNCOEO_01250	2.86e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKBNCOEO_01251	2.06e-278	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HKBNCOEO_01252	4.88e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKBNCOEO_01253	5.94e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HKBNCOEO_01254	4.61e-223	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKBNCOEO_01255	2e-205	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKBNCOEO_01256	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HKBNCOEO_01257	1.61e-244	-	-	-	-	-	-	-	-
HKBNCOEO_01258	3.42e-297	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKBNCOEO_01259	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKBNCOEO_01260	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HKBNCOEO_01261	4.92e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKBNCOEO_01262	2.29e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKBNCOEO_01263	7.54e-200	-	-	-	G	-	-	-	Fructosamine kinase
HKBNCOEO_01264	1.51e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKBNCOEO_01265	1.78e-168	-	-	-	S	-	-	-	PAC2 family
HKBNCOEO_01271	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKBNCOEO_01272	1.6e-144	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
HKBNCOEO_01273	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HKBNCOEO_01274	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HKBNCOEO_01275	1.19e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKBNCOEO_01276	2.48e-253	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKBNCOEO_01277	6.21e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HKBNCOEO_01278	1.86e-129	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKBNCOEO_01279	4.18e-282	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKBNCOEO_01280	5.31e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKBNCOEO_01281	2.3e-295	-	-	-	-	-	-	-	-
HKBNCOEO_01282	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKBNCOEO_01283	3.55e-43	-	-	-	-	-	-	-	-
HKBNCOEO_01284	2.36e-175	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKBNCOEO_01285	9.06e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKBNCOEO_01286	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKBNCOEO_01288	8.84e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKBNCOEO_01289	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKBNCOEO_01290	0.0	-	-	-	K	-	-	-	WYL domain
HKBNCOEO_01291	4.22e-70	-	-	-	-	-	-	-	-
HKBNCOEO_01292	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HKBNCOEO_01293	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HKBNCOEO_01294	6.16e-178	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKBNCOEO_01295	1.21e-48	-	-	-	-	-	-	-	-
HKBNCOEO_01296	3.89e-87	-	-	-	-	-	-	-	-
HKBNCOEO_01297	2.6e-142	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKBNCOEO_01298	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HKBNCOEO_01299	6.51e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HKBNCOEO_01300	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HKBNCOEO_01301	4.04e-217	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HKBNCOEO_01302	3.69e-135	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKBNCOEO_01303	3.56e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HKBNCOEO_01304	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HKBNCOEO_01305	7.16e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HKBNCOEO_01306	1.11e-239	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKBNCOEO_01307	1.03e-206	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKBNCOEO_01308	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKBNCOEO_01309	1.84e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
HKBNCOEO_01310	4.15e-196	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKBNCOEO_01311	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HKBNCOEO_01313	6.97e-240	-	-	-	V	-	-	-	VanZ like family
HKBNCOEO_01314	2.85e-18	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
HKBNCOEO_01315	5e-42	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
HKBNCOEO_01316	3.57e-35	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HKBNCOEO_01317	1.1e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_01318	3.88e-62	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKBNCOEO_01319	1.49e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKBNCOEO_01320	2.55e-65	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKBNCOEO_01322	1.16e-42	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01323	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01324	1.66e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_01325	1.47e-210	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HKBNCOEO_01326	7.45e-181	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HKBNCOEO_01327	2.77e-189	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
HKBNCOEO_01328	2.25e-300	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKBNCOEO_01329	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HKBNCOEO_01330	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HKBNCOEO_01331	0.0	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKBNCOEO_01332	8.82e-141	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HKBNCOEO_01333	1.38e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HKBNCOEO_01334	5.54e-127	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKBNCOEO_01335	6.43e-284	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKBNCOEO_01336	2.78e-34	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HKBNCOEO_01337	9.92e-91	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HKBNCOEO_01338	2.08e-75	-	-	-	L	-	-	-	IstB-like ATP binding protein
HKBNCOEO_01339	1.93e-210	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_01341	3.34e-30	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_01342	5.55e-169	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HKBNCOEO_01343	2.43e-263	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_01344	2.38e-84	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_01345	6.16e-119	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
HKBNCOEO_01346	2.59e-25	-	-	-	S	-	-	-	AAA ATPase domain
HKBNCOEO_01347	2.28e-128	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKBNCOEO_01348	1.98e-59	-	-	-	L	-	-	-	Transposase, Mutator family
HKBNCOEO_01349	4.55e-86	-	-	-	-	-	-	-	-
HKBNCOEO_01350	3.37e-109	-	-	-	-	-	-	-	-
HKBNCOEO_01351	9.99e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_01352	1.53e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HKBNCOEO_01353	1.01e-187	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKBNCOEO_01354	8.22e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKBNCOEO_01355	6.89e-278	-	-	-	GK	-	-	-	ROK family
HKBNCOEO_01356	1.12e-203	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HKBNCOEO_01357	0.0	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HKBNCOEO_01358	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HKBNCOEO_01359	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HKBNCOEO_01360	7.98e-151	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HKBNCOEO_01361	5.31e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_01362	9.29e-67	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HKBNCOEO_01363	2.48e-276	-	-	-	L	-	-	-	Transposase, Mutator family
HKBNCOEO_01364	2.01e-68	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HKBNCOEO_01365	2.66e-58	-	-	-	K	-	-	-	Addiction module
HKBNCOEO_01367	2.16e-103	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HKBNCOEO_01368	1.3e-183	-	-	-	P	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKBNCOEO_01369	7e-121	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HKBNCOEO_01370	3.84e-156	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HKBNCOEO_01371	7.88e-239	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	family 5
HKBNCOEO_01372	7.29e-26	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HKBNCOEO_01373	1.6e-83	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HKBNCOEO_01375	8.06e-298	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01376	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01377	1.84e-206	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01378	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKBNCOEO_01379	7.29e-220	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HKBNCOEO_01380	3.27e-187	traX	-	-	S	-	-	-	TraX protein
HKBNCOEO_01381	5.58e-248	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_01382	3.71e-37	-	-	-	L	-	-	-	Helix-turn-helix domain
HKBNCOEO_01383	3.31e-228	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
HKBNCOEO_01384	2.87e-166	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
HKBNCOEO_01385	9.15e-188	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01386	1.28e-219	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKBNCOEO_01387	4.18e-280	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HKBNCOEO_01389	3.36e-196	-	2.7.8.12	-	S	ko:K09809	-	ko00000,ko01000	Glycosyl transferase family 2
HKBNCOEO_01390	6.16e-33	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKBNCOEO_01396	9e-48	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HKBNCOEO_01397	6.02e-37	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HKBNCOEO_01398	5.82e-133	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HKBNCOEO_01399	2.48e-16	-	-	-	S	-	-	-	Unextendable partial coding region
HKBNCOEO_01401	4.24e-78	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HKBNCOEO_01402	6.86e-213	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HKBNCOEO_01404	6e-244	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKBNCOEO_01405	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HKBNCOEO_01406	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKBNCOEO_01407	2.49e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKBNCOEO_01408	2.45e-224	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HKBNCOEO_01409	2.35e-133	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HKBNCOEO_01410	5.43e-21	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HKBNCOEO_01411	1.1e-141	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HKBNCOEO_01412	7.57e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HKBNCOEO_01413	1.57e-163	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HKBNCOEO_01414	7.43e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HKBNCOEO_01415	1.69e-155	-	-	-	D	-	-	-	bacterial-type flagellum organization
HKBNCOEO_01416	2.43e-241	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HKBNCOEO_01417	1.2e-93	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HKBNCOEO_01418	3.27e-149	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HKBNCOEO_01419	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HKBNCOEO_01420	2.92e-75	-	-	-	U	-	-	-	TadE-like protein
HKBNCOEO_01421	3.01e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HKBNCOEO_01422	1.09e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HKBNCOEO_01423	2.69e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_01424	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HKBNCOEO_01425	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKBNCOEO_01426	2.81e-37	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HKBNCOEO_01427	7.89e-270	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKBNCOEO_01428	1.1e-90	-	-	-	V	-	-	-	Abi-like protein
HKBNCOEO_01429	1.31e-245	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HKBNCOEO_01430	6.3e-174	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKBNCOEO_01431	6.76e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HKBNCOEO_01432	7.59e-269	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKBNCOEO_01433	2.83e-144	-	-	-	-	-	-	-	-
HKBNCOEO_01434	2.11e-221	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
HKBNCOEO_01435	2.48e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKBNCOEO_01436	1.2e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKBNCOEO_01437	4.05e-204	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
HKBNCOEO_01438	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKBNCOEO_01439	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01440	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKBNCOEO_01441	2.39e-188	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01442	1.83e-231	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HKBNCOEO_01443	3.54e-188	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKBNCOEO_01444	4.83e-17	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HKBNCOEO_01445	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HKBNCOEO_01446	1.84e-312	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_01447	3.99e-196	-	-	-	K	-	-	-	FCD
HKBNCOEO_01448	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKBNCOEO_01449	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKBNCOEO_01450	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HKBNCOEO_01451	2.87e-214	-	-	-	I	-	-	-	PAP2 superfamily
HKBNCOEO_01452	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKBNCOEO_01453	1.68e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKBNCOEO_01454	1.85e-265	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKBNCOEO_01455	5.22e-137	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_01456	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HKBNCOEO_01457	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKBNCOEO_01458	5.95e-135	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKBNCOEO_01459	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HKBNCOEO_01460	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HKBNCOEO_01461	1.11e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HKBNCOEO_01462	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
HKBNCOEO_01463	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_01464	4.34e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKBNCOEO_01465	3.5e-205	-	-	-	-	-	-	-	-
HKBNCOEO_01466	3.62e-289	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKBNCOEO_01467	1.24e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKBNCOEO_01469	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKBNCOEO_01472	7e-38	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKBNCOEO_01473	8.34e-28	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKBNCOEO_01475	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HKBNCOEO_01476	1.89e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HKBNCOEO_01477	2.03e-291	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HKBNCOEO_01478	6.04e-290	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKBNCOEO_01479	5.7e-278	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKBNCOEO_01480	1.14e-186	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_01481	6.54e-100	-	-	-	S	-	-	-	FMN_bind
HKBNCOEO_01482	1.62e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01483	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HKBNCOEO_01484	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HKBNCOEO_01485	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HKBNCOEO_01486	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKBNCOEO_01487	3.54e-193	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HKBNCOEO_01488	8.56e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HKBNCOEO_01489	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKBNCOEO_01490	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKBNCOEO_01492	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HKBNCOEO_01493	2.2e-251	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HKBNCOEO_01494	4.13e-193	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_01495	1.69e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKBNCOEO_01496	1.12e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HKBNCOEO_01497	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HKBNCOEO_01498	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HKBNCOEO_01499	4.25e-305	dinF	-	-	V	-	-	-	MatE
HKBNCOEO_01500	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKBNCOEO_01501	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HKBNCOEO_01502	1.29e-180	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HKBNCOEO_01503	1.91e-52	-	-	-	S	-	-	-	granule-associated protein
HKBNCOEO_01504	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HKBNCOEO_01505	2.87e-89	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HKBNCOEO_01506	1.39e-296	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
HKBNCOEO_01507	3.01e-197	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKBNCOEO_01508	3.31e-238	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKBNCOEO_01509	1.41e-59	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HKBNCOEO_01510	9.3e-149	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_01511	7.54e-186	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_01512	6.93e-06	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
HKBNCOEO_01513	4.51e-148	-	-	-	K	-	-	-	WHG domain
HKBNCOEO_01514	1.75e-143	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
HKBNCOEO_01515	8.96e-212	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKBNCOEO_01516	3.3e-295	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKBNCOEO_01517	2.06e-182	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HKBNCOEO_01518	2.62e-29	-	-	-	-	-	-	-	-
HKBNCOEO_01519	4.53e-16	-	-	-	-	-	-	-	-
HKBNCOEO_01521	3.89e-212	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKBNCOEO_01522	1.08e-111	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
HKBNCOEO_01523	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKBNCOEO_01524	1.98e-18	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01525	1.84e-212	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKBNCOEO_01529	6.25e-213	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKBNCOEO_01530	1.15e-163	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKBNCOEO_01531	2.45e-29	-	-	-	-	-	-	-	-
HKBNCOEO_01532	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HKBNCOEO_01533	1.92e-66	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKBNCOEO_01534	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKBNCOEO_01535	3.33e-217	-	-	-	G	-	-	-	Acyltransferase family
HKBNCOEO_01536	8.17e-112	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HKBNCOEO_01537	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HKBNCOEO_01538	6.83e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HKBNCOEO_01539	3.01e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HKBNCOEO_01540	2.08e-264	-	-	-	S	-	-	-	AAA ATPase domain
HKBNCOEO_01541	3.58e-300	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKBNCOEO_01542	1.55e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKBNCOEO_01543	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_01544	3.46e-157	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HKBNCOEO_01547	4e-21	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_01548	3.64e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKBNCOEO_01549	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKBNCOEO_01550	3.42e-259	-	-	-	V	-	-	-	VanZ like family
HKBNCOEO_01551	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01552	2.81e-13	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HKBNCOEO_01553	3.55e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKBNCOEO_01554	6.05e-89	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HKBNCOEO_01555	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKBNCOEO_01556	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKBNCOEO_01557	3.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HKBNCOEO_01558	2.26e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKBNCOEO_01559	4.88e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKBNCOEO_01560	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKBNCOEO_01561	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HKBNCOEO_01562	2.15e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKBNCOEO_01563	2.94e-236	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HKBNCOEO_01564	1.97e-119	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HKBNCOEO_01565	3.56e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKBNCOEO_01566	5.17e-223	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HKBNCOEO_01567	3.33e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKBNCOEO_01568	2.45e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKBNCOEO_01569	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HKBNCOEO_01570	0.0	-	-	-	-	-	-	-	-
HKBNCOEO_01571	5.27e-211	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HKBNCOEO_01572	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HKBNCOEO_01573	4.16e-143	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HKBNCOEO_01574	2.47e-222	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKBNCOEO_01575	7.89e-216	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKBNCOEO_01576	6.72e-282	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HKBNCOEO_01578	2.54e-181	-	-	-	O	-	-	-	Thioredoxin
HKBNCOEO_01579	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKBNCOEO_01580	1.97e-143	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HKBNCOEO_01581	4.57e-152	-	-	-	T	-	-	-	LytTr DNA-binding domain
HKBNCOEO_01582	2.82e-167	-	-	-	T	-	-	-	GHKL domain
HKBNCOEO_01583	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HKBNCOEO_01584	1.03e-73	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HKBNCOEO_01585	5.89e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HKBNCOEO_01586	7.8e-156	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKBNCOEO_01587	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HKBNCOEO_01588	6.17e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKBNCOEO_01590	1.34e-56	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKBNCOEO_01591	8.53e-115	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HKBNCOEO_01592	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKBNCOEO_01594	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKBNCOEO_01595	1.68e-274	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKBNCOEO_01596	1.66e-95	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKBNCOEO_01597	1.04e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKBNCOEO_01598	3.12e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKBNCOEO_01599	7.15e-176	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
HKBNCOEO_01600	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKBNCOEO_01601	2.53e-60	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HKBNCOEO_01602	7.18e-31	-	-	-	L	-	-	-	Winged helix-turn helix
HKBNCOEO_01604	2.72e-231	-	-	-	-	-	-	-	-
HKBNCOEO_01605	4.32e-191	-	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKBNCOEO_01606	3.89e-223	rbsA	3.6.3.17	-	G	ko:K10441,ko:K10542,ko:K17215	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01607	6.91e-187	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HKBNCOEO_01608	1.13e-166	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_01609	7.31e-22	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HKBNCOEO_01610	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
HKBNCOEO_01611	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKBNCOEO_01612	3.02e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKBNCOEO_01613	1.22e-175	-	-	-	-	-	-	-	-
HKBNCOEO_01614	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HKBNCOEO_01615	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKBNCOEO_01616	2.35e-210	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HKBNCOEO_01617	3.08e-220	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKBNCOEO_01618	8.98e-27	-	-	-	-	-	-	-	-
HKBNCOEO_01619	5.1e-160	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKBNCOEO_01620	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKBNCOEO_01621	1.14e-105	-	-	-	-	-	-	-	-
HKBNCOEO_01622	1.43e-142	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HKBNCOEO_01623	2.47e-193	-	-	-	-	-	-	-	-
HKBNCOEO_01624	6.17e-189	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HKBNCOEO_01625	1.02e-158	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKBNCOEO_01626	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HKBNCOEO_01627	1.77e-102	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKBNCOEO_01628	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HKBNCOEO_01629	8.97e-294	-	-	-	GK	-	-	-	ROK family
HKBNCOEO_01630	3.13e-310	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01631	5.6e-206	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01632	7.15e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01634	7.85e-290	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HKBNCOEO_01639	2.11e-98	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HKBNCOEO_01641	4.15e-134	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HKBNCOEO_01642	8.55e-85	-	-	-	L	-	-	-	Integrase core domain
HKBNCOEO_01643	9.49e-178	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKBNCOEO_01644	1.14e-68	-	-	-	-	-	-	-	-
HKBNCOEO_01645	2.24e-238	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKBNCOEO_01646	1.41e-243	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKBNCOEO_01647	5.06e-234	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKBNCOEO_01648	4.92e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKBNCOEO_01649	2.03e-251	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKBNCOEO_01650	1.1e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HKBNCOEO_01651	4.29e-08	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
HKBNCOEO_01652	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKBNCOEO_01653	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HKBNCOEO_01654	1.57e-80	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKBNCOEO_01655	2.1e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKBNCOEO_01656	7.82e-183	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HKBNCOEO_01657	1.34e-191	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HKBNCOEO_01658	1.93e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKBNCOEO_01659	1.11e-150	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKBNCOEO_01660	4.33e-196	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HKBNCOEO_01661	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKBNCOEO_01662	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HKBNCOEO_01663	1.07e-207	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HKBNCOEO_01664	1.92e-301	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HKBNCOEO_01665	3.49e-24	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HKBNCOEO_01666	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKBNCOEO_01667	1.49e-176	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01668	4.2e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
HKBNCOEO_01669	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HKBNCOEO_01670	5.73e-101	-	-	-	-	-	-	-	-
HKBNCOEO_01671	3.21e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HKBNCOEO_01672	1.36e-242	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HKBNCOEO_01673	9.63e-56	-	-	-	-	-	-	-	-
HKBNCOEO_01674	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKBNCOEO_01675	7.44e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_01676	2.96e-242	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HKBNCOEO_01677	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKBNCOEO_01678	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01679	2.12e-228	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HKBNCOEO_01680	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKBNCOEO_01681	1.13e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HKBNCOEO_01682	3.99e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HKBNCOEO_01683	2.99e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HKBNCOEO_01684	1.86e-306	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKBNCOEO_01685	5.29e-127	-	-	-	-	-	-	-	-
HKBNCOEO_01686	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKBNCOEO_01687	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKBNCOEO_01688	6.43e-153	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01689	1.86e-105	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKBNCOEO_01690	2.33e-174	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKBNCOEO_01691	3.21e-211	-	-	-	EG	-	-	-	EamA-like transporter family
HKBNCOEO_01692	6.23e-186	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HKBNCOEO_01693	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKBNCOEO_01694	3.38e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKBNCOEO_01695	3.87e-193	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKBNCOEO_01696	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HKBNCOEO_01697	4.89e-152	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKBNCOEO_01698	1.54e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKBNCOEO_01699	2.3e-101	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKBNCOEO_01700	9.29e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HKBNCOEO_01701	1.29e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKBNCOEO_01702	1.84e-132	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HKBNCOEO_01703	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKBNCOEO_01704	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKBNCOEO_01705	5.12e-243	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKBNCOEO_01706	1.89e-158	-	-	-	-	-	-	-	-
HKBNCOEO_01707	2.4e-169	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HKBNCOEO_01708	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HKBNCOEO_01709	1.95e-250	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKBNCOEO_01710	2.58e-141	-	-	-	-	-	-	-	-
HKBNCOEO_01711	2.4e-248	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKBNCOEO_01712	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HKBNCOEO_01713	1.25e-284	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKBNCOEO_01714	1.17e-218	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKBNCOEO_01715	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HKBNCOEO_01718	3.14e-27	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKBNCOEO_01719	7.07e-127	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01720	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HKBNCOEO_01721	7.3e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HKBNCOEO_01722	2.05e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HKBNCOEO_01723	4.95e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HKBNCOEO_01724	2.39e-108	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HKBNCOEO_01725	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKBNCOEO_01726	8.07e-133	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKBNCOEO_01727	1.31e-98	-	-	-	-	-	-	-	-
HKBNCOEO_01729	7.8e-299	-	-	-	S	-	-	-	HipA-like C-terminal domain
HKBNCOEO_01730	6.44e-64	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HKBNCOEO_01732	1.53e-35	-	-	-	-	-	-	-	-
HKBNCOEO_01733	3.41e-183	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKBNCOEO_01734	4.26e-62	-	-	-	L	-	-	-	Integrase core domain
HKBNCOEO_01735	1.93e-61	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKBNCOEO_01736	5.79e-71	-	-	-	L	-	-	-	Transposase
HKBNCOEO_01737	9.5e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HKBNCOEO_01738	7.21e-205	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01739	1.99e-207	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01740	2.11e-309	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01741	6.09e-276	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_01742	4.86e-29	-	-	-	-	-	-	-	-
HKBNCOEO_01744	2.11e-77	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HKBNCOEO_01745	6.07e-27	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HKBNCOEO_01746	3.9e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKBNCOEO_01747	2.83e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HKBNCOEO_01748	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HKBNCOEO_01749	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HKBNCOEO_01750	4e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKBNCOEO_01751	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HKBNCOEO_01755	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKBNCOEO_01756	1.32e-183	-	-	-	-	-	-	-	-
HKBNCOEO_01757	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKBNCOEO_01758	2.06e-78	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HKBNCOEO_01759	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
HKBNCOEO_01760	1.92e-120	-	-	-	NO	-	-	-	SAF
HKBNCOEO_01761	8.07e-34	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HKBNCOEO_01762	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HKBNCOEO_01763	2.22e-273	-	-	-	T	-	-	-	Forkhead associated domain
HKBNCOEO_01764	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKBNCOEO_01765	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKBNCOEO_01766	5.66e-186	-	-	-	S	-	-	-	alpha beta
HKBNCOEO_01767	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HKBNCOEO_01768	1.57e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKBNCOEO_01769	1.86e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HKBNCOEO_01770	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKBNCOEO_01771	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HKBNCOEO_01772	1.5e-182	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKBNCOEO_01773	1.14e-276	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HKBNCOEO_01774	7.6e-305	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HKBNCOEO_01775	2.11e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKBNCOEO_01776	9.45e-300	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKBNCOEO_01777	2.3e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKBNCOEO_01778	1.97e-111	-	-	-	G	ko:K12112	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001	YhcH YjgK YiaL family protein
HKBNCOEO_01779	0.0	-	3.2.1.23	-	G	ko:K12111	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01780	6.14e-147	pgmB	5.4.2.6	-	S	ko:K01838,ko:K04844	ko00500,map00500	ko00000,ko00001,ko01000	phosphonoacetaldehyde hydrolase activity
HKBNCOEO_01781	6.58e-200	-	-	-	EG	-	-	-	EamA-like transporter family
HKBNCOEO_01782	0.0	kojP	2.4.1.230, 2.4.1.64	GH65	G	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HKBNCOEO_01783	1.51e-195	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01784	5.76e-216	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01785	2.04e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01786	1.59e-241	-	-	-	K	-	-	-	Periplasmic binding protein domain
HKBNCOEO_01787	1.41e-127	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HKBNCOEO_01788	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKBNCOEO_01789	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKBNCOEO_01790	6.94e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
HKBNCOEO_01791	6.14e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKBNCOEO_01792	1.56e-192	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKBNCOEO_01793	5.84e-252	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HKBNCOEO_01794	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HKBNCOEO_01795	2.38e-225	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKBNCOEO_01796	1.17e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HKBNCOEO_01797	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HKBNCOEO_01798	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HKBNCOEO_01799	2.02e-246	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HKBNCOEO_01800	7.26e-302	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HKBNCOEO_01801	2.28e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKBNCOEO_01802	3.59e-82	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HKBNCOEO_01803	2.07e-71	-	-	-	L	-	-	-	RelB antitoxin
HKBNCOEO_01804	1.49e-30	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
HKBNCOEO_01805	1.41e-244	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKBNCOEO_01806	1.28e-12	-	-	-	-	-	-	-	-
HKBNCOEO_01810	1.01e-58	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HKBNCOEO_01811	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HKBNCOEO_01812	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HKBNCOEO_01813	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HKBNCOEO_01815	1.6e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKBNCOEO_01816	3.7e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HKBNCOEO_01817	0.0	-	-	-	-	-	-	-	-
HKBNCOEO_01818	7.54e-211	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKBNCOEO_01819	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKBNCOEO_01820	2.9e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKBNCOEO_01821	6.32e-55	-	-	-	-	-	-	-	-
HKBNCOEO_01822	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HKBNCOEO_01823	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HKBNCOEO_01824	1.05e-177	nfrA	-	-	C	-	-	-	Nitroreductase family
HKBNCOEO_01825	6.43e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HKBNCOEO_01826	1.29e-132	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HKBNCOEO_01827	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01828	1.4e-235	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_01829	3.3e-200	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01830	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKBNCOEO_01831	9.49e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HKBNCOEO_01832	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HKBNCOEO_01833	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKBNCOEO_01834	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKBNCOEO_01835	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKBNCOEO_01836	8.11e-121	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKBNCOEO_01837	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_01838	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKBNCOEO_01839	4.14e-229	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKBNCOEO_01840	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HKBNCOEO_01842	8.72e-235	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKBNCOEO_01843	5.33e-156	-	-	-	-	-	-	-	-
HKBNCOEO_01844	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKBNCOEO_01845	2.02e-62	-	-	-	-	-	-	-	-
HKBNCOEO_01846	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKBNCOEO_01847	3.53e-228	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01848	8.61e-227	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HKBNCOEO_01849	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKBNCOEO_01850	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKBNCOEO_01851	2.41e-44	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKBNCOEO_01852	1.48e-71	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKBNCOEO_01853	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HKBNCOEO_01854	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
HKBNCOEO_01855	5.81e-249	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKBNCOEO_01856	9.99e-309	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKBNCOEO_01857	3.14e-227	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01858	3.67e-196	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKBNCOEO_01859	7.96e-243	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HKBNCOEO_01860	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKBNCOEO_01861	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HKBNCOEO_01862	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKBNCOEO_01863	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKBNCOEO_01864	1.92e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HKBNCOEO_01865	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKBNCOEO_01866	4.08e-204	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HKBNCOEO_01867	1.01e-179	-	-	-	T	ko:K06950	-	ko00000	HD domain
HKBNCOEO_01868	1.88e-243	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKBNCOEO_01869	0.0	-	-	-	V	-	-	-	ABC transporter permease
HKBNCOEO_01870	1.61e-309	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HKBNCOEO_01871	3.42e-270	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKBNCOEO_01872	6.77e-219	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKBNCOEO_01873	0.0	-	-	-	-	-	-	-	-
HKBNCOEO_01874	1.39e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKBNCOEO_01875	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKBNCOEO_01876	4.97e-218	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKBNCOEO_01877	7.29e-231	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKBNCOEO_01878	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
HKBNCOEO_01879	1.44e-192	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKBNCOEO_01880	1.26e-299	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKBNCOEO_01881	0.0	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKBNCOEO_01882	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HKBNCOEO_01883	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HKBNCOEO_01884	4.78e-58	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HKBNCOEO_01887	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HKBNCOEO_01888	7.05e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HKBNCOEO_01889	1.09e-226	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKBNCOEO_01890	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HKBNCOEO_01891	5.88e-297	-	-	-	M	-	-	-	Glycosyl transferase family 21
HKBNCOEO_01892	4.06e-246	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01893	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKBNCOEO_01894	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HKBNCOEO_01895	1.78e-263	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKBNCOEO_01896	2.66e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKBNCOEO_01897	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKBNCOEO_01899	7.27e-139	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HKBNCOEO_01900	3.57e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKBNCOEO_01901	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKBNCOEO_01902	2.23e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HKBNCOEO_01903	1.48e-216	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HKBNCOEO_01904	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HKBNCOEO_01905	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKBNCOEO_01907	2.48e-227	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKBNCOEO_01908	8.08e-117	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKBNCOEO_01909	9.34e-23	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HKBNCOEO_01910	7.01e-210	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HKBNCOEO_01911	1.76e-94	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKBNCOEO_01912	2.4e-187	-	-	-	-	-	-	-	-
HKBNCOEO_01913	1.2e-90	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HKBNCOEO_01915	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HKBNCOEO_01916	5.78e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKBNCOEO_01917	2.39e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKBNCOEO_01918	5.37e-271	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKBNCOEO_01919	1.08e-196	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKBNCOEO_01920	1.25e-240	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKBNCOEO_01921	2.73e-205	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HKBNCOEO_01922	4.8e-159	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKBNCOEO_01923	2.92e-153	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HKBNCOEO_01924	9.69e-275	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HKBNCOEO_01925	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKBNCOEO_01926	3.86e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HKBNCOEO_01927	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HKBNCOEO_01928	0.0	-	-	-	S	ko:K06990	-	ko00000,ko04812	AMMECR1
HKBNCOEO_01929	2.78e-254	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HKBNCOEO_01930	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKBNCOEO_01931	2.29e-152	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HKBNCOEO_01932	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HKBNCOEO_01933	2.29e-196	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKBNCOEO_01934	1.25e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HKBNCOEO_01935	6.38e-315	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HKBNCOEO_01936	7.18e-218	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HKBNCOEO_01937	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HKBNCOEO_01938	3.54e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_01939	1.24e-114	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HKBNCOEO_01940	2.14e-257	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKBNCOEO_01941	6.37e-299	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HKBNCOEO_01942	2.39e-228	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HKBNCOEO_01943	1.21e-268	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HKBNCOEO_01945	7.41e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKBNCOEO_01946	1.35e-87	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKBNCOEO_01947	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HKBNCOEO_01948	3.71e-122	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
HKBNCOEO_01949	1.02e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKBNCOEO_01950	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKBNCOEO_01951	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HKBNCOEO_01952	2.3e-174	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKBNCOEO_01953	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HKBNCOEO_01954	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HKBNCOEO_01955	5.49e-183	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKBNCOEO_01956	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HKBNCOEO_01958	5.86e-61	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HKBNCOEO_01959	1.26e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HKBNCOEO_01960	3.88e-308	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKBNCOEO_01961	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKBNCOEO_01962	1.6e-220	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKBNCOEO_01963	0.0	-	-	-	M	-	-	-	domain protein
HKBNCOEO_01964	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
HKBNCOEO_01966	1.84e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKBNCOEO_01967	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HKBNCOEO_01968	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKBNCOEO_01969	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKBNCOEO_01970	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HKBNCOEO_01971	5.98e-243	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_01972	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HKBNCOEO_01973	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HKBNCOEO_01974	1.15e-257	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKBNCOEO_01975	1.02e-63	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKBNCOEO_01976	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKBNCOEO_01977	1.24e-200	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKBNCOEO_01978	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKBNCOEO_01979	2.27e-307	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKBNCOEO_01980	1e-248	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKBNCOEO_01981	2.17e-214	-	-	-	EG	-	-	-	EamA-like transporter family
HKBNCOEO_01983	9.22e-217	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKBNCOEO_01984	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HKBNCOEO_01985	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKBNCOEO_01986	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HKBNCOEO_01987	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKBNCOEO_01989	6.07e-192	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HKBNCOEO_01990	1.65e-115	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
HKBNCOEO_01991	1.23e-69	-	-	-	S	-	-	-	Putative heavy-metal-binding
HKBNCOEO_01992	1.1e-208	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HKBNCOEO_01993	1.91e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4928)
HKBNCOEO_01994	1.24e-215	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HKBNCOEO_01995	8.49e-313	-	-	-	L	-	-	-	Z1 domain
HKBNCOEO_01996	6.73e-40	-	-	-	S	-	-	-	Putative PD-(D/E)XK family member, (DUF4420)
HKBNCOEO_01998	1.62e-295	-	-	-	S	-	-	-	AIPR protein
HKBNCOEO_01999	8.56e-217	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HKBNCOEO_02000	2.82e-210	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKBNCOEO_02001	5.4e-252	-	-	-	S	-	-	-	Fic/DOC family
HKBNCOEO_02002	1.01e-168	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HKBNCOEO_02003	5.21e-256	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKBNCOEO_02004	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HKBNCOEO_02005	0.0	-	-	-	S	-	-	-	Putative esterase
HKBNCOEO_02006	7.42e-28	-	-	-	-	-	-	-	-
HKBNCOEO_02007	3.74e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HKBNCOEO_02008	2.45e-119	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
HKBNCOEO_02009	1.08e-270	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HKBNCOEO_02010	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HKBNCOEO_02011	8.7e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HKBNCOEO_02012	8.95e-105	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HKBNCOEO_02013	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HKBNCOEO_02014	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKBNCOEO_02015	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HKBNCOEO_02016	1.54e-221	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HKBNCOEO_02017	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HKBNCOEO_02018	9.12e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HKBNCOEO_02019	3.94e-292	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKBNCOEO_02020	1.56e-162	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HKBNCOEO_02021	1.98e-100	crgA	-	-	D	-	-	-	Involved in cell division
HKBNCOEO_02022	2.82e-177	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HKBNCOEO_02023	2.96e-47	-	-	-	-	-	-	-	-
HKBNCOEO_02024	1.18e-52	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties