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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOHAOBKO_00001	1.31e-37	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_00002	3.92e-22	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_00003	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOHAOBKO_00004	1e-91	-	-	-	-	-	-	-	-
IOHAOBKO_00005	9.44e-314	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
IOHAOBKO_00006	1.59e-241	-	-	-	-	-	-	-	-
IOHAOBKO_00007	1.21e-219	-	-	-	S	ko:K21688	-	ko00000	G5
IOHAOBKO_00008	1.59e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
IOHAOBKO_00009	1.83e-156	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
IOHAOBKO_00010	2e-204	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IOHAOBKO_00011	2.94e-282	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
IOHAOBKO_00012	3.63e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IOHAOBKO_00013	1.65e-283	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
IOHAOBKO_00014	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
IOHAOBKO_00015	2.09e-244	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOHAOBKO_00016	7.37e-272	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
IOHAOBKO_00017	2.9e-167	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IOHAOBKO_00018	0.0	pon1	-	-	M	-	-	-	Transglycosylase
IOHAOBKO_00019	8.2e-304	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IOHAOBKO_00020	2.17e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
IOHAOBKO_00021	5.12e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
IOHAOBKO_00022	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
IOHAOBKO_00023	4.15e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
IOHAOBKO_00024	1.26e-19	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
IOHAOBKO_00025	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IOHAOBKO_00026	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IOHAOBKO_00027	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOHAOBKO_00028	1.2e-236	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
IOHAOBKO_00029	1.05e-163	-	-	-	-	-	-	-	-
IOHAOBKO_00030	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOHAOBKO_00031	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOHAOBKO_00032	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
IOHAOBKO_00033	5.35e-307	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOHAOBKO_00034	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
IOHAOBKO_00035	5.07e-283	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOHAOBKO_00036	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
IOHAOBKO_00037	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
IOHAOBKO_00038	1.51e-297	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOHAOBKO_00039	9.28e-170	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOHAOBKO_00040	2.56e-212	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOHAOBKO_00041	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOHAOBKO_00042	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
IOHAOBKO_00043	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOHAOBKO_00044	3.57e-157	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOHAOBKO_00045	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_00046	8.44e-262	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOHAOBKO_00047	3.08e-267	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
IOHAOBKO_00048	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
IOHAOBKO_00049	9.07e-206	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
IOHAOBKO_00050	1.33e-105	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOHAOBKO_00051	1.15e-196	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOHAOBKO_00052	6.49e-217	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
IOHAOBKO_00053	1.79e-221	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00054	3.69e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00055	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOHAOBKO_00056	1.58e-200	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
IOHAOBKO_00057	2.38e-233	-	-	-	K	-	-	-	Periplasmic binding protein domain
IOHAOBKO_00058	2.3e-186	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_00059	1.43e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOHAOBKO_00060	1.66e-42	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOHAOBKO_00062	1.6e-291	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
IOHAOBKO_00063	1.56e-294	-	-	-	G	-	-	-	polysaccharide deacetylase
IOHAOBKO_00064	2.92e-247	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOHAOBKO_00065	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOHAOBKO_00066	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
IOHAOBKO_00067	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOHAOBKO_00068	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
IOHAOBKO_00069	7.01e-293	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
IOHAOBKO_00070	1.58e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IOHAOBKO_00071	1.72e-213	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
IOHAOBKO_00072	1.15e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
IOHAOBKO_00073	9.55e-271	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
IOHAOBKO_00074	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
IOHAOBKO_00075	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
IOHAOBKO_00076	4.75e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IOHAOBKO_00077	1.24e-281	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
IOHAOBKO_00078	2.04e-175	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00079	1.21e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
IOHAOBKO_00080	6.46e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IOHAOBKO_00081	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
IOHAOBKO_00082	1.23e-233	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOHAOBKO_00083	1.31e-302	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
IOHAOBKO_00084	1.49e-294	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
IOHAOBKO_00085	5.66e-75	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOHAOBKO_00086	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOHAOBKO_00087	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOHAOBKO_00088	4.49e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_00089	1.99e-282	-	-	-	G	-	-	-	Transmembrane secretion effector
IOHAOBKO_00090	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOHAOBKO_00091	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
IOHAOBKO_00092	2.62e-201	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOHAOBKO_00093	8.62e-155	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00094	1.55e-178	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00095	1.68e-132	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
IOHAOBKO_00096	9.29e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00097	2.51e-281	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
IOHAOBKO_00098	3.71e-47	-	-	-	T	-	-	-	Histidine kinase
IOHAOBKO_00099	1.31e-17	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
IOHAOBKO_00100	1.9e-170	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOHAOBKO_00101	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOHAOBKO_00102	2.37e-181	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
IOHAOBKO_00103	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOHAOBKO_00104	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOHAOBKO_00105	5.47e-314	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
IOHAOBKO_00106	2.83e-175	-	-	-	-	-	-	-	-
IOHAOBKO_00107	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
IOHAOBKO_00108	8.49e-66	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00109	9.47e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOHAOBKO_00110	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOHAOBKO_00111	2.57e-274	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
IOHAOBKO_00112	1.68e-277	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOHAOBKO_00114	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOHAOBKO_00115	6.94e-210	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
IOHAOBKO_00116	7.26e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
IOHAOBKO_00117	5.17e-162	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
IOHAOBKO_00118	3.44e-216	-	-	-	-	-	-	-	-
IOHAOBKO_00119	3.28e-297	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IOHAOBKO_00120	3.16e-82	-	-	-	K	-	-	-	Helix-turn-helix domain
IOHAOBKO_00121	9.2e-10	-	-	-	S	-	-	-	PIN domain
IOHAOBKO_00122	1.86e-59	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
IOHAOBKO_00123	7e-70	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
IOHAOBKO_00124	6.17e-97	-	-	-	P	-	-	-	branched-chain amino acid ABC transporter, permease protein
IOHAOBKO_00125	7.71e-144	-	-	-	G	-	-	-	ATPases associated with a variety of cellular activities
IOHAOBKO_00126	1.04e-97	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
IOHAOBKO_00127	5.5e-211	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
IOHAOBKO_00128	5.72e-90	xylR	-	-	GK	-	-	-	ROK family
IOHAOBKO_00129	2.37e-58	-	-	-	-	-	-	-	-
IOHAOBKO_00130	4.24e-217	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOHAOBKO_00131	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
IOHAOBKO_00132	1.4e-192	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
IOHAOBKO_00134	5.17e-126	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_00135	2.76e-162	-	-	-	-	-	-	-	-
IOHAOBKO_00136	7.22e-240	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOHAOBKO_00137	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOHAOBKO_00138	8.26e-106	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOHAOBKO_00139	6.66e-281	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOHAOBKO_00140	2.91e-278	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
IOHAOBKO_00141	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOHAOBKO_00142	6.83e-132	-	-	-	-	-	-	-	-
IOHAOBKO_00143	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
IOHAOBKO_00144	4.47e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOHAOBKO_00145	6.4e-241	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOHAOBKO_00146	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOHAOBKO_00147	1.74e-96	-	-	-	K	-	-	-	Transcriptional regulator
IOHAOBKO_00148	5.41e-253	-	-	-	S	-	-	-	Protein conserved in bacteria
IOHAOBKO_00149	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
IOHAOBKO_00150	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
IOHAOBKO_00151	1.58e-209	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
IOHAOBKO_00152	2.49e-265	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOHAOBKO_00153	5.97e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOHAOBKO_00155	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00156	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00157	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
IOHAOBKO_00158	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
IOHAOBKO_00159	1.15e-259	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
IOHAOBKO_00160	3.09e-224	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOHAOBKO_00161	2.47e-153	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_00162	3.31e-300	tcsS3	-	-	KT	-	-	-	PspC domain
IOHAOBKO_00163	0.0	pspC	-	-	KT	-	-	-	PspC domain
IOHAOBKO_00164	7.82e-105	-	-	-	-	-	-	-	-
IOHAOBKO_00165	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
IOHAOBKO_00166	1.83e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
IOHAOBKO_00167	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
IOHAOBKO_00168	3.82e-276	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
IOHAOBKO_00170	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOHAOBKO_00171	2.77e-222	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IOHAOBKO_00172	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOHAOBKO_00173	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IOHAOBKO_00174	1.68e-234	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOHAOBKO_00175	2.3e-44	-	-	-	-	-	-	-	-
IOHAOBKO_00176	1.6e-268	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOHAOBKO_00177	2.08e-216	-	-	-	S	-	-	-	CHAP domain
IOHAOBKO_00178	1.3e-141	-	-	-	M	-	-	-	NlpC/P60 family
IOHAOBKO_00179	1.08e-142	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IOHAOBKO_00181	2.25e-240	-	-	-	T	-	-	-	Universal stress protein family
IOHAOBKO_00182	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
IOHAOBKO_00183	8.56e-215	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOHAOBKO_00184	1.2e-161	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
IOHAOBKO_00185	3.01e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
IOHAOBKO_00186	9.79e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_00187	5.09e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
IOHAOBKO_00188	1.03e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOHAOBKO_00189	7.34e-12	-	-	-	L	-	-	-	HTH-like domain
IOHAOBKO_00190	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOHAOBKO_00191	1.83e-278	-	-	-	GK	-	-	-	ROK family
IOHAOBKO_00192	3.96e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00193	5.83e-28	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_00194	2.07e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IOHAOBKO_00195	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOHAOBKO_00198	1.72e-97	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_00199	1.27e-291	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOHAOBKO_00200	4.3e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_00201	5.74e-41	-	-	-	L	-	-	-	Transposase DDE domain
IOHAOBKO_00202	3.76e-17	-	-	-	L	-	-	-	Transposase DDE domain
IOHAOBKO_00203	2.34e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_00204	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOHAOBKO_00205	9.62e-116	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOHAOBKO_00206	3.56e-104	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOHAOBKO_00207	1.35e-94	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IOHAOBKO_00208	2.07e-145	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
IOHAOBKO_00211	5.1e-126	-	-	-	-	-	-	-	-
IOHAOBKO_00212	0.0	-	-	-	M	-	-	-	Conserved repeat domain
IOHAOBKO_00213	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
IOHAOBKO_00215	2.87e-112	-	-	-	-	-	-	-	-
IOHAOBKO_00216	6.46e-145	-	-	-	-	-	-	-	-
IOHAOBKO_00217	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOHAOBKO_00218	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOHAOBKO_00219	4.3e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IOHAOBKO_00220	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOHAOBKO_00221	1.21e-14	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOHAOBKO_00222	7.26e-72	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOHAOBKO_00223	1.67e-84	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IOHAOBKO_00224	1.42e-28	-	-	-	-	-	-	-	-
IOHAOBKO_00225	2.87e-216	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOHAOBKO_00226	3.03e-257	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOHAOBKO_00227	5.15e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOHAOBKO_00228	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOHAOBKO_00229	9.48e-85	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOHAOBKO_00230	2.08e-274	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
IOHAOBKO_00231	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOHAOBKO_00232	2.72e-208	-	-	-	P	-	-	-	Cation efflux family
IOHAOBKO_00233	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOHAOBKO_00234	9.61e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
IOHAOBKO_00235	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
IOHAOBKO_00236	8.06e-96	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
IOHAOBKO_00237	1.52e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
IOHAOBKO_00238	4.76e-119	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IOHAOBKO_00239	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
IOHAOBKO_00240	7.11e-172	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOHAOBKO_00241	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOHAOBKO_00242	3.89e-151	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IOHAOBKO_00243	1.47e-155	-	-	-	-	-	-	-	-
IOHAOBKO_00244	5.54e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOHAOBKO_00245	4.23e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
IOHAOBKO_00246	9.67e-251	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
IOHAOBKO_00247	7.41e-102	-	-	-	K	-	-	-	MerR, DNA binding
IOHAOBKO_00248	5.52e-152	-	-	-	-	-	-	-	-
IOHAOBKO_00249	1.98e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOHAOBKO_00250	4.49e-185	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOHAOBKO_00251	2.55e-170	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOHAOBKO_00252	1.09e-225	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
IOHAOBKO_00255	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOHAOBKO_00256	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00257	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00258	1.95e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOHAOBKO_00259	4.43e-221	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOHAOBKO_00260	2.34e-205	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOHAOBKO_00261	7.92e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_00262	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOHAOBKO_00263	3.21e-66	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
IOHAOBKO_00264	3.51e-11	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
IOHAOBKO_00266	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
IOHAOBKO_00267	6.35e-51	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
IOHAOBKO_00268	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00269	1.94e-14	-	-	-	L	-	-	-	Transposase DDE domain
IOHAOBKO_00270	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
IOHAOBKO_00271	7.28e-173	-	-	-	M	-	-	-	Mechanosensitive ion channel
IOHAOBKO_00272	8.39e-236	-	-	-	S	-	-	-	CAAX protease self-immunity
IOHAOBKO_00273	1.12e-303	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOHAOBKO_00274	3.37e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00275	4.85e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00276	3.04e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00277	7.06e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOHAOBKO_00278	1.38e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IOHAOBKO_00279	1.78e-241	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IOHAOBKO_00280	3.27e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
IOHAOBKO_00283	3.19e-151	-	-	-	S	-	-	-	CYTH
IOHAOBKO_00284	5.98e-218	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
IOHAOBKO_00285	3.14e-230	-	-	-	-	-	-	-	-
IOHAOBKO_00286	5.45e-243	-	-	-	-	-	-	-	-
IOHAOBKO_00287	2.43e-214	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
IOHAOBKO_00288	1.23e-165	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IOHAOBKO_00289	3.62e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOHAOBKO_00290	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOHAOBKO_00291	1.2e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOHAOBKO_00292	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOHAOBKO_00293	4.31e-193	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOHAOBKO_00294	6.77e-99	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOHAOBKO_00295	1.42e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOHAOBKO_00296	1.33e-187	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOHAOBKO_00297	4.09e-262	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOHAOBKO_00299	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
IOHAOBKO_00300	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
IOHAOBKO_00301	9.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IOHAOBKO_00302	1.11e-125	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOHAOBKO_00303	1.04e-153	-	-	-	-	-	-	-	-
IOHAOBKO_00304	2.67e-179	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
IOHAOBKO_00305	8.09e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOHAOBKO_00306	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOHAOBKO_00307	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOHAOBKO_00308	0.0	-	-	-	S	-	-	-	domain protein
IOHAOBKO_00309	1.89e-82	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
IOHAOBKO_00310	4.7e-62	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
IOHAOBKO_00311	3.01e-46	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_00312	3.15e-27	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_00313	2.52e-157	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IOHAOBKO_00314	1.09e-145	araQ	-	-	U	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00315	7.2e-159	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00316	4.35e-191	araN	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00317	1.25e-44	-	-	-	K	-	-	-	AraC-like ligand binding domain
IOHAOBKO_00318	1.42e-144	-	-	-	L	ko:K07485	-	ko00000	Transposase
IOHAOBKO_00319	5.23e-59	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
IOHAOBKO_00320	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOHAOBKO_00321	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
IOHAOBKO_00322	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
IOHAOBKO_00323	9.64e-248	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_00324	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOHAOBKO_00325	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOHAOBKO_00326	7.57e-68	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOHAOBKO_00327	3.05e-204	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_00328	5.99e-226	-	-	-	-	-	-	-	-
IOHAOBKO_00329	9.54e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOHAOBKO_00330	2.85e-215	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
IOHAOBKO_00331	3.99e-141	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOHAOBKO_00332	2.18e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
IOHAOBKO_00333	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
IOHAOBKO_00334	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IOHAOBKO_00335	2.45e-161	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOHAOBKO_00337	1.72e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IOHAOBKO_00338	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOHAOBKO_00339	4.09e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IOHAOBKO_00340	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOHAOBKO_00341	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOHAOBKO_00342	3.91e-245	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_00343	2.6e-58	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_00344	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IOHAOBKO_00345	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
IOHAOBKO_00346	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
IOHAOBKO_00347	5.09e-124	-	-	-	F	-	-	-	NUDIX domain
IOHAOBKO_00348	5.61e-311	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
IOHAOBKO_00349	5.46e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOHAOBKO_00350	1.07e-264	-	-	-	GK	-	-	-	ROK family
IOHAOBKO_00351	2e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOHAOBKO_00353	6.67e-281	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOHAOBKO_00354	5.56e-215	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOHAOBKO_00355	8.35e-07	-	-	-	-	-	-	-	-
IOHAOBKO_00357	3.94e-229	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
IOHAOBKO_00358	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOHAOBKO_00359	1.38e-275	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOHAOBKO_00360	2.45e-288	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
IOHAOBKO_00361	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOHAOBKO_00362	1.58e-263	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOHAOBKO_00363	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOHAOBKO_00364	3.7e-200	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOHAOBKO_00365	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
IOHAOBKO_00366	1.84e-90	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IOHAOBKO_00367	2.09e-243	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOHAOBKO_00368	2.33e-120	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOHAOBKO_00369	0.0	-	-	-	L	-	-	-	DNA helicase
IOHAOBKO_00370	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IOHAOBKO_00371	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOHAOBKO_00372	1.43e-67	-	-	-	M	-	-	-	Lysin motif
IOHAOBKO_00373	4.82e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOHAOBKO_00374	1.39e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOHAOBKO_00375	2.67e-224	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOHAOBKO_00376	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOHAOBKO_00377	1.99e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
IOHAOBKO_00378	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
IOHAOBKO_00379	1.24e-279	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
IOHAOBKO_00380	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOHAOBKO_00381	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
IOHAOBKO_00382	5.86e-168	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
IOHAOBKO_00383	3.43e-154	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOHAOBKO_00384	7.57e-163	-	-	-	-	-	-	-	-
IOHAOBKO_00385	1.66e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
IOHAOBKO_00386	1.57e-279	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOHAOBKO_00387	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOHAOBKO_00388	4.18e-71	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
IOHAOBKO_00389	7.81e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
IOHAOBKO_00390	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
IOHAOBKO_00391	7.85e-210	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
IOHAOBKO_00393	1.39e-186	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
IOHAOBKO_00394	1.18e-312	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
IOHAOBKO_00395	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00396	5.59e-224	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00397	2.27e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00398	8.17e-109	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
IOHAOBKO_00401	4.92e-18	-	-	-	S	-	-	-	Psort location Extracellular, score 8.82
IOHAOBKO_00402	1.59e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOHAOBKO_00405	3.83e-17	-	-	-	-	-	-	-	-
IOHAOBKO_00406	5.77e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_00407	3.63e-274	-	-	-	G	-	-	-	Transmembrane secretion effector
IOHAOBKO_00408	1.76e-23	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
IOHAOBKO_00409	1.04e-307	-	-	-	S	-	-	-	HipA-like C-terminal domain
IOHAOBKO_00410	1.52e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOHAOBKO_00411	9.65e-143	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00412	2.26e-153	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00413	7.78e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
IOHAOBKO_00414	4e-198	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOHAOBKO_00415	2.3e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOHAOBKO_00416	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
IOHAOBKO_00417	0.0	-	-	-	T	-	-	-	Histidine kinase
IOHAOBKO_00418	1.18e-179	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_00419	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOHAOBKO_00420	2.44e-214	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_00421	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
IOHAOBKO_00422	2.26e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IOHAOBKO_00423	4.32e-29	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOHAOBKO_00424	2.51e-98	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
IOHAOBKO_00425	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
IOHAOBKO_00426	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
IOHAOBKO_00427	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
IOHAOBKO_00428	4e-233	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
IOHAOBKO_00429	1.88e-145	safC	-	-	S	-	-	-	O-methyltransferase
IOHAOBKO_00430	2.65e-214	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOHAOBKO_00431	5.35e-305	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IOHAOBKO_00432	2.41e-302	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
IOHAOBKO_00435	9.18e-317	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOHAOBKO_00436	1.28e-155	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOHAOBKO_00437	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOHAOBKO_00438	1.85e-78	-	-	-	-	-	-	-	-
IOHAOBKO_00439	1.76e-312	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOHAOBKO_00440	3.47e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOHAOBKO_00441	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
IOHAOBKO_00442	7.83e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
IOHAOBKO_00443	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOHAOBKO_00444	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
IOHAOBKO_00445	1.24e-51	-	-	-	-	-	-	-	-
IOHAOBKO_00446	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IOHAOBKO_00447	5.66e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
IOHAOBKO_00448	3.9e-146	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00449	6.93e-281	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOHAOBKO_00450	4.26e-224	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
IOHAOBKO_00451	1.15e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOHAOBKO_00454	7.2e-174	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IOHAOBKO_00455	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOHAOBKO_00456	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOHAOBKO_00457	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
IOHAOBKO_00458	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOHAOBKO_00459	3.48e-23	-	-	-	-	-	-	-	-
IOHAOBKO_00460	5.21e-09	-	-	-	-	-	-	-	-
IOHAOBKO_00461	3.59e-38	-	-	-	-	-	-	-	-
IOHAOBKO_00462	4.79e-69	-	-	-	S	-	-	-	Putative DNA-binding domain
IOHAOBKO_00463	3.2e-138	-	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IOHAOBKO_00465	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
IOHAOBKO_00466	1.08e-214	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
IOHAOBKO_00468	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
IOHAOBKO_00469	1.01e-254	-	-	-	K	-	-	-	WYL domain
IOHAOBKO_00470	4.29e-227	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOHAOBKO_00471	2.45e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOHAOBKO_00472	2.85e-105	-	-	-	V	-	-	-	DivIVA protein
IOHAOBKO_00473	3.44e-60	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IOHAOBKO_00474	1.42e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOHAOBKO_00475	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOHAOBKO_00476	2.02e-316	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOHAOBKO_00477	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
IOHAOBKO_00478	1.05e-202	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOHAOBKO_00479	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOHAOBKO_00480	4.39e-287	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
IOHAOBKO_00481	6.57e-182	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOHAOBKO_00482	9.51e-81	-	-	-	S	-	-	-	Thiamine-binding protein
IOHAOBKO_00483	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOHAOBKO_00484	1.18e-293	-	-	-	T	-	-	-	Histidine kinase
IOHAOBKO_00485	5.01e-159	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_00486	8.19e-244	-	-	-	-	-	-	-	-
IOHAOBKO_00487	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
IOHAOBKO_00488	8.6e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_00489	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
IOHAOBKO_00490	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOHAOBKO_00491	6.61e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOHAOBKO_00492	8.77e-193	-	-	-	C	-	-	-	Putative TM nitroreductase
IOHAOBKO_00493	1.55e-252	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
IOHAOBKO_00494	4.04e-134	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOHAOBKO_00495	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_00496	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
IOHAOBKO_00497	1.66e-70	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IOHAOBKO_00498	2.26e-67	-	-	-	-	-	-	-	-
IOHAOBKO_00499	5.73e-239	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOHAOBKO_00500	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_00501	1.53e-41	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOHAOBKO_00502	2.53e-14	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOHAOBKO_00503	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
IOHAOBKO_00504	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
IOHAOBKO_00505	8.51e-254	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
IOHAOBKO_00506	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
IOHAOBKO_00507	6.56e-145	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
IOHAOBKO_00508	0.0	-	-	-	I	-	-	-	PAP2 superfamily
IOHAOBKO_00509	1.27e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00510	2.44e-143	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00511	3.54e-186	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOHAOBKO_00512	6.38e-196	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
IOHAOBKO_00513	5.22e-131	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IOHAOBKO_00514	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOHAOBKO_00515	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
IOHAOBKO_00516	0.0	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
IOHAOBKO_00517	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
IOHAOBKO_00518	4.49e-182	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
IOHAOBKO_00519	0.0	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IOHAOBKO_00521	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
IOHAOBKO_00522	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
IOHAOBKO_00523	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
IOHAOBKO_00524	2.31e-230	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOHAOBKO_00525	7.53e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
IOHAOBKO_00526	1.75e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOHAOBKO_00527	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOHAOBKO_00528	2.48e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
IOHAOBKO_00529	2.67e-148	-	-	-	-	-	-	-	-
IOHAOBKO_00530	6.57e-54	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
IOHAOBKO_00531	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOHAOBKO_00532	1.54e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IOHAOBKO_00533	8.33e-127	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
IOHAOBKO_00534	8.09e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOHAOBKO_00535	1.53e-245	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
IOHAOBKO_00536	3.97e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
IOHAOBKO_00537	2.68e-118	-	-	-	-	-	-	-	-
IOHAOBKO_00538	7.54e-242	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IOHAOBKO_00539	4.24e-213	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
IOHAOBKO_00540	8.64e-76	-	-	-	-	-	-	-	-
IOHAOBKO_00541	0.0	-	-	-	S	-	-	-	PGAP1-like protein
IOHAOBKO_00542	2.13e-143	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOHAOBKO_00543	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
IOHAOBKO_00544	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
IOHAOBKO_00545	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
IOHAOBKO_00546	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IOHAOBKO_00547	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
IOHAOBKO_00548	4.8e-224	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
IOHAOBKO_00549	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
IOHAOBKO_00550	4.32e-173	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
IOHAOBKO_00551	4.16e-229	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
IOHAOBKO_00552	2.2e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOHAOBKO_00553	5.44e-104	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOHAOBKO_00554	3.14e-94	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOHAOBKO_00555	0.0	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
IOHAOBKO_00556	4.48e-170	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOHAOBKO_00557	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
IOHAOBKO_00558	3.4e-162	-	-	-	S	-	-	-	SNARE associated Golgi protein
IOHAOBKO_00559	3.93e-152	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
IOHAOBKO_00560	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOHAOBKO_00561	8.38e-169	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOHAOBKO_00562	1.51e-234	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOHAOBKO_00563	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
IOHAOBKO_00564	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOHAOBKO_00565	1.67e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOHAOBKO_00566	4.94e-211	-	-	-	G	-	-	-	Fic/DOC family
IOHAOBKO_00567	2.3e-62	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
IOHAOBKO_00568	4.78e-110	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOHAOBKO_00569	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
IOHAOBKO_00570	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
IOHAOBKO_00571	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
IOHAOBKO_00572	1.01e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00573	2.78e-222	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00574	7.2e-200	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00575	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IOHAOBKO_00576	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IOHAOBKO_00577	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
IOHAOBKO_00578	2.45e-262	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_00579	5.35e-311	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
IOHAOBKO_00580	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
IOHAOBKO_00581	8.47e-42	-	-	-	-	-	-	-	-
IOHAOBKO_00582	4.85e-167	-	-	-	C	-	-	-	Putative TM nitroreductase
IOHAOBKO_00583	1.12e-216	-	-	-	EG	-	-	-	EamA-like transporter family
IOHAOBKO_00584	2.35e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
IOHAOBKO_00585	4.05e-294	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
IOHAOBKO_00586	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
IOHAOBKO_00587	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IOHAOBKO_00588	6.18e-205	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOHAOBKO_00589	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOHAOBKO_00590	9.69e-143	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
IOHAOBKO_00591	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
IOHAOBKO_00592	2.06e-220	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOHAOBKO_00593	8.71e-112	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
IOHAOBKO_00594	1.39e-201	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
IOHAOBKO_00595	3.32e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
IOHAOBKO_00596	1.32e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOHAOBKO_00598	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOHAOBKO_00599	1.33e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOHAOBKO_00600	1.4e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_00601	2.26e-176	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
IOHAOBKO_00602	2.79e-180	-	-	-	S	-	-	-	Fic/DOC family
IOHAOBKO_00605	5.3e-08	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_00607	5.53e-17	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
IOHAOBKO_00608	1.11e-24	-	-	-	L	ko:K07484	-	ko00000	Belongs to the 'phage' integrase family
IOHAOBKO_00609	1.48e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IOHAOBKO_00610	5.62e-226	-	-	-	V	-	-	-	Abi-like protein
IOHAOBKO_00611	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOHAOBKO_00612	1.37e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOHAOBKO_00614	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
IOHAOBKO_00615	1.89e-294	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOHAOBKO_00616	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOHAOBKO_00617	3.26e-274	-	-	-	-	-	-	-	-
IOHAOBKO_00619	2.57e-27	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
IOHAOBKO_00621	2.24e-155	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
IOHAOBKO_00622	3.52e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
IOHAOBKO_00623	9.31e-36	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IOHAOBKO_00624	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOHAOBKO_00625	4.87e-163	-	-	-	L	-	-	-	NUDIX domain
IOHAOBKO_00626	4.64e-227	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
IOHAOBKO_00627	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOHAOBKO_00628	2.41e-166	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
IOHAOBKO_00630	1.59e-138	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IOHAOBKO_00631	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
IOHAOBKO_00632	3.81e-228	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
IOHAOBKO_00633	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOHAOBKO_00634	1.18e-134	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOHAOBKO_00635	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOHAOBKO_00636	3.6e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOHAOBKO_00637	7.52e-264	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOHAOBKO_00638	1.5e-205	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00639	1.1e-174	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
IOHAOBKO_00640	1.77e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOHAOBKO_00641	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
IOHAOBKO_00642	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOHAOBKO_00643	3.51e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
IOHAOBKO_00644	4.09e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOHAOBKO_00645	5.28e-158	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
IOHAOBKO_00646	2.92e-190	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
IOHAOBKO_00647	2.13e-101	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOHAOBKO_00648	0.0	-	-	-	-	-	-	-	-
IOHAOBKO_00649	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
IOHAOBKO_00650	2.06e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOHAOBKO_00651	2.54e-303	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
IOHAOBKO_00652	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
IOHAOBKO_00653	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOHAOBKO_00654	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOHAOBKO_00655	9.75e-192	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
IOHAOBKO_00656	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOHAOBKO_00657	8.17e-98	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
IOHAOBKO_00658	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
IOHAOBKO_00659	2.34e-121	-	-	-	-	-	-	-	-
IOHAOBKO_00660	6.99e-50	int8	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_00661	8.98e-109	int8	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_00667	2.33e-44	-	-	-	-	-	-	-	-
IOHAOBKO_00668	2.07e-11	-	-	-	-	-	-	-	-
IOHAOBKO_00669	2.76e-149	-	-	-	K	-	-	-	Fic/DOC family
IOHAOBKO_00670	2.64e-08	-	-	-	-	-	-	-	-
IOHAOBKO_00671	1.1e-34	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_00672	2.65e-59	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_00673	7.81e-187	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_00674	6.48e-300	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOHAOBKO_00675	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
IOHAOBKO_00676	3.03e-165	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
IOHAOBKO_00677	3.86e-161	-	-	-	P	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00678	5.11e-267	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00679	7.8e-115	-	-	-	L	-	-	-	Resolvase, N terminal domain
IOHAOBKO_00680	1.22e-59	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_00681	1.05e-102	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
IOHAOBKO_00682	5.87e-102	-	-	-	L	-	-	-	HTH-like domain
IOHAOBKO_00684	9.07e-234	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOHAOBKO_00685	2.77e-133	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
IOHAOBKO_00686	1.51e-103	-	-	-	D	-	-	-	Septum formation initiator
IOHAOBKO_00687	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOHAOBKO_00688	1.82e-227	-	-	-	C	-	-	-	Aldo/keto reductase family
IOHAOBKO_00689	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOHAOBKO_00690	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOHAOBKO_00691	7.51e-118	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IOHAOBKO_00692	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
IOHAOBKO_00694	2.65e-194	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOHAOBKO_00696	3.76e-213	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
IOHAOBKO_00697	1.15e-164	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
IOHAOBKO_00698	5.25e-176	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOHAOBKO_00699	1.26e-124	-	-	-	-	-	-	-	-
IOHAOBKO_00700	4.49e-298	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOHAOBKO_00701	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
IOHAOBKO_00702	1.36e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
IOHAOBKO_00703	1.07e-93	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOHAOBKO_00704	3.61e-37	pacL2	3.6.3.8	-	P	ko:K01537,ko:K12955	-	ko00000,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IOHAOBKO_00705	4.04e-125	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOHAOBKO_00706	1.94e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOHAOBKO_00707	1.32e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00708	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IOHAOBKO_00709	1.32e-23	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_00710	1.37e-17	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_00711	1.34e-151	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IOHAOBKO_00712	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOHAOBKO_00713	9.09e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOHAOBKO_00714	4.29e-50	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
IOHAOBKO_00715	1.25e-64	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
IOHAOBKO_00716	7.68e-151	-	-	-	-	-	-	-	-
IOHAOBKO_00717	1.28e-179	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IOHAOBKO_00719	2.4e-257	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
IOHAOBKO_00720	7.66e-308	-	-	-	L	-	-	-	Tetratricopeptide repeat
IOHAOBKO_00721	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOHAOBKO_00722	2.29e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
IOHAOBKO_00723	9.39e-181	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IOHAOBKO_00724	6.92e-133	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOHAOBKO_00725	5.26e-84	-	-	-	P	-	-	-	Rhodanese Homology Domain
IOHAOBKO_00726	1.62e-188	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
IOHAOBKO_00727	1.19e-200	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOHAOBKO_00728	5.91e-38	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
IOHAOBKO_00729	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOHAOBKO_00730	1.2e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOHAOBKO_00731	1.24e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOHAOBKO_00732	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOHAOBKO_00733	1.39e-314	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IOHAOBKO_00734	6.84e-226	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IOHAOBKO_00735	9.26e-270	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOHAOBKO_00736	5.47e-258	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOHAOBKO_00737	5.13e-137	-	-	-	-	-	-	-	-
IOHAOBKO_00738	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
IOHAOBKO_00739	5.07e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOHAOBKO_00740	8.12e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOHAOBKO_00741	1.45e-208	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOHAOBKO_00742	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00743	4.38e-140	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOHAOBKO_00744	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
IOHAOBKO_00745	1.8e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
IOHAOBKO_00746	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOHAOBKO_00747	2.29e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
IOHAOBKO_00748	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOHAOBKO_00749	3.04e-259	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOHAOBKO_00750	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOHAOBKO_00751	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOHAOBKO_00752	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOHAOBKO_00753	3.54e-22	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
IOHAOBKO_00754	3.12e-179	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00755	2.74e-284	-	-	-	E	-	-	-	Aminotransferase class I and II
IOHAOBKO_00756	2.17e-243	-	-	-	P	-	-	-	NMT1/THI5 like
IOHAOBKO_00757	8.22e-172	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00758	1.58e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOHAOBKO_00759	4.62e-164	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOHAOBKO_00760	0.0	-	-	-	I	-	-	-	acetylesterase activity
IOHAOBKO_00761	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOHAOBKO_00762	4.35e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOHAOBKO_00763	2.12e-295	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
IOHAOBKO_00765	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
IOHAOBKO_00766	3.66e-211	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOHAOBKO_00767	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
IOHAOBKO_00768	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOHAOBKO_00769	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
IOHAOBKO_00770	3.25e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
IOHAOBKO_00771	1.54e-216	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
IOHAOBKO_00772	2.39e-166	-	-	-	S	-	-	-	Vitamin K epoxide reductase
IOHAOBKO_00773	9.28e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
IOHAOBKO_00774	4.68e-190	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOHAOBKO_00775	5.74e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
IOHAOBKO_00776	1.74e-72	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_00777	1.79e-170	hflK	-	-	O	-	-	-	prohibitin homologues
IOHAOBKO_00778	1.41e-11	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOHAOBKO_00779	3.8e-56	-	-	-	O	-	-	-	Glutaredoxin
IOHAOBKO_00780	1.83e-297	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOHAOBKO_00781	1.2e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOHAOBKO_00782	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
IOHAOBKO_00783	1.98e-06	-	-	-	-	-	-	-	-
IOHAOBKO_00784	7.2e-175	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
IOHAOBKO_00785	2.64e-135	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOHAOBKO_00786	4.4e-216	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOHAOBKO_00787	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IOHAOBKO_00788	2.95e-306	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IOHAOBKO_00789	1.45e-120	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOHAOBKO_00790	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOHAOBKO_00791	1.23e-162	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00792	2.46e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IOHAOBKO_00793	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IOHAOBKO_00794	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
IOHAOBKO_00795	0.0	-	-	-	M	-	-	-	probably involved in cell wall
IOHAOBKO_00797	4.23e-63	-	4.1.1.44	-	L	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IOHAOBKO_00798	3.4e-236	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IOHAOBKO_00799	2.75e-52	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IOHAOBKO_00800	3.5e-149	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IOHAOBKO_00801	0.000207	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
IOHAOBKO_00802	1.22e-156	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
IOHAOBKO_00803	8.03e-311	-	-	-	V	-	-	-	MatE
IOHAOBKO_00804	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IOHAOBKO_00805	1.33e-176	-	-	-	K	-	-	-	LysR substrate binding domain
IOHAOBKO_00806	4.37e-283	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_00807	2.56e-197	-	-	-	K	-	-	-	LysR substrate binding domain
IOHAOBKO_00808	9.67e-274	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
IOHAOBKO_00810	1.5e-180	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_00811	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
IOHAOBKO_00812	4.88e-176	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOHAOBKO_00813	2.96e-173	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOHAOBKO_00814	3.01e-197	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00815	1.79e-222	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00816	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOHAOBKO_00817	1.06e-297	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
IOHAOBKO_00818	6.01e-186	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IOHAOBKO_00819	8.35e-212	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
IOHAOBKO_00820	2.38e-99	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
IOHAOBKO_00821	1.52e-45	-	-	-	-	-	-	-	-
IOHAOBKO_00822	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_00823	5.61e-251	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOHAOBKO_00824	1.06e-97	-	-	-	K	-	-	-	MerR family regulatory protein
IOHAOBKO_00825	2.12e-114	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOHAOBKO_00826	1.37e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOHAOBKO_00827	2.16e-40	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOHAOBKO_00829	1.02e-236	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IOHAOBKO_00830	4.28e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IOHAOBKO_00831	1.04e-164	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
IOHAOBKO_00832	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOHAOBKO_00833	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOHAOBKO_00834	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOHAOBKO_00835	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOHAOBKO_00836	3.25e-142	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
IOHAOBKO_00838	1.01e-250	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
IOHAOBKO_00839	6.11e-277	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
IOHAOBKO_00840	1.56e-110	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IOHAOBKO_00841	3.76e-57	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
IOHAOBKO_00842	2.09e-18	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IOHAOBKO_00843	4.64e-165	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOHAOBKO_00844	2.78e-82	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOHAOBKO_00846	4.76e-305	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOHAOBKO_00847	4.41e-137	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
IOHAOBKO_00848	5.13e-209	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOHAOBKO_00849	4.87e-298	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
IOHAOBKO_00850	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
IOHAOBKO_00851	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
IOHAOBKO_00852	1.78e-241	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
IOHAOBKO_00853	7.51e-145	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
IOHAOBKO_00854	1.38e-145	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_00855	4.53e-274	-	-	-	T	-	-	-	Histidine kinase
IOHAOBKO_00856	1.01e-13	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOHAOBKO_00857	6.27e-224	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00858	5.48e-281	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOHAOBKO_00859	2.84e-304	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOHAOBKO_00860	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOHAOBKO_00861	2.69e-62	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IOHAOBKO_00862	6.11e-262	-	-	-	-	-	-	-	-
IOHAOBKO_00863	4.17e-142	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
IOHAOBKO_00864	2.51e-137	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
IOHAOBKO_00865	3.78e-219	-	-	-	M	-	-	-	pfam nlp p60
IOHAOBKO_00866	3.68e-195	-	-	-	I	-	-	-	Serine aminopeptidase, S33
IOHAOBKO_00867	4.02e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IOHAOBKO_00868	2.88e-307	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
IOHAOBKO_00869	1.48e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOHAOBKO_00870	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOHAOBKO_00871	4.61e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
IOHAOBKO_00872	1.28e-274	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOHAOBKO_00873	3.15e-203	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOHAOBKO_00874	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOHAOBKO_00875	1.07e-193	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
IOHAOBKO_00876	1.54e-90	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
IOHAOBKO_00877	1.01e-65	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOHAOBKO_00878	1.03e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
IOHAOBKO_00879	6.1e-85	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOHAOBKO_00880	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOHAOBKO_00881	2.43e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
IOHAOBKO_00882	1.28e-76	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IOHAOBKO_00883	6.59e-48	-	-	-	-	-	-	-	-
IOHAOBKO_00884	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOHAOBKO_00885	2.12e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOHAOBKO_00886	2.97e-252	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOHAOBKO_00887	1.74e-91	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
IOHAOBKO_00888	1.01e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOHAOBKO_00889	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOHAOBKO_00890	2.01e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IOHAOBKO_00891	1.24e-120	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_00892	4.21e-31	-	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_00894	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
IOHAOBKO_00895	1.2e-262	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IOHAOBKO_00896	0.0	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
IOHAOBKO_00897	0.0	-	2.1.1.72	-	L	ko:K07317	-	ko00000,ko01000,ko02048	Eco57I restriction-modification methylase
IOHAOBKO_00898	3.7e-233	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	BsuBI/PstI restriction endonuclease C-terminus
IOHAOBKO_00899	9.61e-287	-	-	-	-	-	-	-	-
IOHAOBKO_00901	6.83e-89	-	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_00902	5.25e-107	-	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_00903	9.48e-47	-	-	-	M	-	-	-	Peptidase family M23
IOHAOBKO_00904	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
IOHAOBKO_00905	9.53e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
IOHAOBKO_00906	4.18e-262	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
IOHAOBKO_00907	5.83e-120	-	-	-	-	-	-	-	-
IOHAOBKO_00908	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
IOHAOBKO_00909	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOHAOBKO_00910	1.56e-191	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOHAOBKO_00911	3.6e-183	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOHAOBKO_00912	1.09e-170	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOHAOBKO_00913	7.06e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOHAOBKO_00914	6.76e-222	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
IOHAOBKO_00915	1.85e-284	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOHAOBKO_00916	7.48e-68	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IOHAOBKO_00917	4.75e-21	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IOHAOBKO_00918	1.18e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOHAOBKO_00919	1.32e-92	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOHAOBKO_00920	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOHAOBKO_00921	5.46e-118	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
IOHAOBKO_00922	3.58e-206	-	-	-	-	-	-	-	-
IOHAOBKO_00923	2.3e-96	-	-	-	-	-	-	-	-
IOHAOBKO_00924	5.5e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
IOHAOBKO_00925	5.32e-11	-	-	-	-	-	-	-	-
IOHAOBKO_00926	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
IOHAOBKO_00927	1.77e-27	-	-	-	G	-	-	-	Major facilitator Superfamily
IOHAOBKO_00928	2.68e-54	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_00929	8.55e-120	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
IOHAOBKO_00930	8.81e-150	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
IOHAOBKO_00931	7.15e-43	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
IOHAOBKO_00932	4.3e-120	-	-	-	-	-	-	-	-
IOHAOBKO_00935	3.17e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00936	2.58e-167	-	-	-	-	-	-	-	-
IOHAOBKO_00937	8.32e-133	-	-	-	-	-	-	-	-
IOHAOBKO_00938	4.12e-178	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
IOHAOBKO_00939	1.68e-51	-	-	-	-	-	-	-	-
IOHAOBKO_00940	8.76e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
IOHAOBKO_00941	8.31e-115	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_00942	1.64e-119	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_00943	4.54e-83	-	2.7.13.3	-	T	ko:K07675	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOHAOBKO_00944	7.78e-71	-	-	-	S	-	-	-	SdpI/YhfL protein family
IOHAOBKO_00945	6.37e-125	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
IOHAOBKO_00946	3.28e-36	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOHAOBKO_00947	8.13e-18	-	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_00948	8.73e-35	-	-	-	S	-	-	-	PIN domain
IOHAOBKO_00949	2.32e-58	-	-	-	S	-	-	-	Helix-turn-helix domain
IOHAOBKO_00950	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
IOHAOBKO_00951	2.32e-152	-	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
IOHAOBKO_00952	2.17e-122	-	-	-	K	-	-	-	FR47-like protein
IOHAOBKO_00953	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
IOHAOBKO_00954	7.39e-54	-	-	-	-	-	-	-	-
IOHAOBKO_00955	3.57e-130	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
IOHAOBKO_00956	1.47e-111	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
IOHAOBKO_00957	6.06e-274	-	-	-	S	-	-	-	Helix-turn-helix domain
IOHAOBKO_00958	1.19e-15	-	-	-	S	-	-	-	Helix-turn-helix domain
IOHAOBKO_00960	5.23e-89	-	-	-	-	-	-	-	-
IOHAOBKO_00961	1.57e-214	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00962	4.22e-193	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_00963	6.51e-176	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
IOHAOBKO_00964	1.6e-175	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_00965	8.21e-245	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IOHAOBKO_00966	1.02e-279	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IOHAOBKO_00967	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IOHAOBKO_00968	4.78e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOHAOBKO_00969	4.31e-133	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOHAOBKO_00970	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
IOHAOBKO_00971	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOHAOBKO_00972	1.14e-307	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
IOHAOBKO_00973	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOHAOBKO_00974	8.7e-91	-	-	-	S	-	-	-	PIN domain
IOHAOBKO_00975	1.15e-47	-	-	-	-	-	-	-	-
IOHAOBKO_00976	1.63e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOHAOBKO_00977	1.2e-148	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOHAOBKO_00978	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
IOHAOBKO_00979	9.59e-268	-	-	-	P	-	-	-	Citrate transporter
IOHAOBKO_00980	9.8e-41	-	-	-	-	-	-	-	-
IOHAOBKO_00981	2.24e-50	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
IOHAOBKO_00982	2.93e-201	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IOHAOBKO_00985	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_00986	9.75e-295	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_00987	2.36e-90	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOHAOBKO_00988	8.1e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOHAOBKO_00989	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOHAOBKO_00990	2e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOHAOBKO_00991	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOHAOBKO_00992	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOHAOBKO_00993	1.05e-127	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOHAOBKO_00994	5.04e-315	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOHAOBKO_00995	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOHAOBKO_00996	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
IOHAOBKO_00997	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOHAOBKO_00998	3.09e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOHAOBKO_00999	5.43e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOHAOBKO_01000	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOHAOBKO_01001	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOHAOBKO_01002	3.93e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOHAOBKO_01003	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOHAOBKO_01004	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOHAOBKO_01005	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOHAOBKO_01006	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOHAOBKO_01007	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOHAOBKO_01008	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOHAOBKO_01009	1.09e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOHAOBKO_01010	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOHAOBKO_01011	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOHAOBKO_01012	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOHAOBKO_01013	9.78e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOHAOBKO_01014	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOHAOBKO_01015	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOHAOBKO_01016	3.82e-176	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IOHAOBKO_01017	7.26e-185	-	-	-	S	-	-	-	YwiC-like protein
IOHAOBKO_01018	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IOHAOBKO_01019	2.64e-217	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOHAOBKO_01020	6.49e-245	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
IOHAOBKO_01021	1.73e-248	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01022	2.69e-272	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
IOHAOBKO_01023	2.66e-97	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOHAOBKO_01024	3.04e-296	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01025	2.47e-227	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IOHAOBKO_01026	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOHAOBKO_01027	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOHAOBKO_01028	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOHAOBKO_01029	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IOHAOBKO_01030	9.47e-152	-	-	-	-	-	-	-	-
IOHAOBKO_01031	9.37e-142	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
IOHAOBKO_01032	6.76e-233	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOHAOBKO_01033	3.07e-19	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
IOHAOBKO_01034	2.49e-47	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
IOHAOBKO_01035	1.43e-63	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
IOHAOBKO_01036	1.44e-42	-	-	-	-	-	-	-	-
IOHAOBKO_01037	7.33e-183	-	-	-	-	-	-	-	-
IOHAOBKO_01038	1.64e-86	-	-	-	S	-	-	-	PrgI family protein
IOHAOBKO_01039	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
IOHAOBKO_01040	0.0	-	-	-	M	-	-	-	CHAP domain
IOHAOBKO_01041	8.71e-242	-	-	-	-	-	-	-	-
IOHAOBKO_01043	5.72e-83	-	-	-	S	-	-	-	Putative amidase domain
IOHAOBKO_01044	1.82e-126	-	-	-	S	-	-	-	Putative amidase domain
IOHAOBKO_01045	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
IOHAOBKO_01046	7.51e-78	-	-	-	-	-	-	-	-
IOHAOBKO_01047	4.83e-61	-	-	-	-	-	-	-	-
IOHAOBKO_01048	5.89e-161	-	-	-	-	-	-	-	-
IOHAOBKO_01049	0.0	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
IOHAOBKO_01050	4.93e-220	-	-	-	-	-	-	-	-
IOHAOBKO_01051	2.72e-207	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
IOHAOBKO_01052	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
IOHAOBKO_01053	2.35e-92	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
IOHAOBKO_01054	1.85e-110	-	-	-	-	-	-	-	-
IOHAOBKO_01055	2.58e-62	-	-	-	-	-	-	-	-
IOHAOBKO_01056	0.0	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
IOHAOBKO_01057	1.15e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF4192)
IOHAOBKO_01058	1.45e-296	-	-	-	T	-	-	-	Histidine kinase
IOHAOBKO_01059	1.55e-160	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_01060	2.21e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOHAOBKO_01061	1.06e-24	-	-	-	-	-	-	-	-
IOHAOBKO_01062	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOHAOBKO_01063	2.87e-42	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOHAOBKO_01064	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOHAOBKO_01066	9.4e-187	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Thiopeptide-type bacteriocin biosynthesis domain protein
IOHAOBKO_01067	1.44e-131	-	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Psort location Cytoplasmic, score
IOHAOBKO_01069	3.22e-146	-	-	-	V	-	-	-	VanZ like family
IOHAOBKO_01070	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
IOHAOBKO_01071	1.51e-206	-	-	-	-	-	-	-	-
IOHAOBKO_01072	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
IOHAOBKO_01073	3.7e-19	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
IOHAOBKO_01074	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
IOHAOBKO_01075	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
IOHAOBKO_01076	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
IOHAOBKO_01077	1.63e-195	-	-	-	P	-	-	-	VTC domain
IOHAOBKO_01078	4.71e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
IOHAOBKO_01079	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
IOHAOBKO_01080	1.27e-118	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOHAOBKO_01081	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOHAOBKO_01082	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOHAOBKO_01083	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IOHAOBKO_01084	1.57e-53	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOHAOBKO_01085	4.81e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
IOHAOBKO_01086	0.0	-	-	-	S	-	-	-	Amidohydrolase family
IOHAOBKO_01087	5.93e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOHAOBKO_01088	2.08e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
IOHAOBKO_01089	4.6e-147	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOHAOBKO_01090	6.47e-266	-	-	-	T	-	-	-	Histidine kinase
IOHAOBKO_01091	8.23e-294	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01092	2.13e-94	-	-	-	I	-	-	-	Sterol carrier protein
IOHAOBKO_01094	6.66e-298	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOHAOBKO_01095	1.14e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOHAOBKO_01096	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
IOHAOBKO_01097	8.75e-298	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOHAOBKO_01098	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
IOHAOBKO_01099	3.12e-143	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
IOHAOBKO_01100	1.96e-131	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
IOHAOBKO_01101	1.95e-19	-	-	-	C	-	-	-	Aldo/keto reductase family
IOHAOBKO_01102	1.63e-43	-	-	-	-	-	-	-	-
IOHAOBKO_01103	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
IOHAOBKO_01104	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOHAOBKO_01105	6.44e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOHAOBKO_01106	7.04e-308	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOHAOBKO_01107	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
IOHAOBKO_01108	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOHAOBKO_01109	7.06e-198	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
IOHAOBKO_01110	6.55e-93	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOHAOBKO_01111	3.18e-282	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOHAOBKO_01112	3.44e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOHAOBKO_01113	3.27e-230	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
IOHAOBKO_01114	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOHAOBKO_01115	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOHAOBKO_01116	3.69e-248	-	-	-	M	-	-	-	Conserved repeat domain
IOHAOBKO_01117	1.54e-182	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01118	1.78e-241	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOHAOBKO_01119	1.75e-117	-	-	-	K	-	-	-	MarR family
IOHAOBKO_01120	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_01121	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOHAOBKO_01122	1.69e-171	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_01123	6.44e-177	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
IOHAOBKO_01124	8.7e-214	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOHAOBKO_01125	7.24e-185	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOHAOBKO_01126	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOHAOBKO_01127	1e-76	-	-	-	L	ko:K07485	-	ko00000	Transposase
IOHAOBKO_01128	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
IOHAOBKO_01129	9.86e-177	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
IOHAOBKO_01130	0.0	-	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
IOHAOBKO_01131	5.28e-201	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
IOHAOBKO_01132	3.43e-170	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
IOHAOBKO_01133	5.83e-251	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOHAOBKO_01134	1.65e-48	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOHAOBKO_01137	2.08e-131	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01138	4.98e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
IOHAOBKO_01139	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01140	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01141	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01142	1.29e-183	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOHAOBKO_01143	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOHAOBKO_01144	4.32e-298	intA	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_01145	1.55e-103	-	-	-	-	-	-	-	-
IOHAOBKO_01146	4.61e-167	-	-	-	-	-	-	-	-
IOHAOBKO_01149	6.67e-311	intA	-	-	L	-	-	-	Phage integrase family
IOHAOBKO_01150	1.78e-43	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOHAOBKO_01151	7.61e-72	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOHAOBKO_01152	3.67e-172	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
IOHAOBKO_01153	1.23e-35	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOHAOBKO_01155	8.73e-154	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01156	3.3e-138	-	-	-	-	-	-	-	-
IOHAOBKO_01157	2.76e-104	-	-	-	-	-	-	-	-
IOHAOBKO_01160	5.75e-50	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
IOHAOBKO_01161	2.3e-56	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	PFAM ABC-2 type transporter
IOHAOBKO_01162	0.0	-	-	-	M	-	-	-	Cell surface antigen C-terminus
IOHAOBKO_01164	6.52e-157	-	-	-	K	-	-	-	Helix-turn-helix domain protein
IOHAOBKO_01165	2.46e-36	-	-	-	-	-	-	-	-
IOHAOBKO_01166	1.03e-91	-	-	-	-	-	-	-	-
IOHAOBKO_01167	1.43e-47	-	-	-	-	-	-	-	-
IOHAOBKO_01168	5.1e-134	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
IOHAOBKO_01169	3.71e-127	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
IOHAOBKO_01170	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOHAOBKO_01171	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
IOHAOBKO_01172	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
IOHAOBKO_01173	1.24e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
IOHAOBKO_01174	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IOHAOBKO_01175	1.25e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOHAOBKO_01176	4.82e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IOHAOBKO_01177	2.19e-142	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IOHAOBKO_01178	3.09e-307	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOHAOBKO_01179	7.89e-212	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
IOHAOBKO_01181	1.21e-192	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOHAOBKO_01182	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IOHAOBKO_01183	3.27e-276	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
IOHAOBKO_01184	1.33e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOHAOBKO_01185	0.0	corC	-	-	S	-	-	-	CBS domain
IOHAOBKO_01186	9.08e-235	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOHAOBKO_01187	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOHAOBKO_01188	1.34e-260	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
IOHAOBKO_01189	3.42e-56	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
IOHAOBKO_01190	8.58e-308	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IOHAOBKO_01191	5.08e-299	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IOHAOBKO_01192	1.08e-129	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOHAOBKO_01193	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
IOHAOBKO_01194	2.95e-187	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01195	4.82e-179	-	-	-	S	-	-	-	UPF0126 domain
IOHAOBKO_01196	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOHAOBKO_01197	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOHAOBKO_01198	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOHAOBKO_01200	9.59e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_01201	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
IOHAOBKO_01202	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOHAOBKO_01204	2.86e-58	-	-	-	-	-	-	-	-
IOHAOBKO_01205	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOHAOBKO_01206	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
IOHAOBKO_01207	2.41e-106	-	-	-	-	-	-	-	-
IOHAOBKO_01208	1.6e-310	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
IOHAOBKO_01209	4.18e-202	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01210	3.18e-201	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOHAOBKO_01211	5.35e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
IOHAOBKO_01212	4.24e-182	-	-	-	-	-	-	-	-
IOHAOBKO_01213	1.89e-101	-	-	-	L	-	-	-	Transposase, Mutator family
IOHAOBKO_01216	2.39e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOHAOBKO_01217	1.93e-117	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
IOHAOBKO_01218	1.64e-186	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
IOHAOBKO_01219	4.16e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOHAOBKO_01221	4.32e-172	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOHAOBKO_01222	9.33e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IOHAOBKO_01223	5.84e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
IOHAOBKO_01225	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOHAOBKO_01226	2.74e-208	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
IOHAOBKO_01227	3.45e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOHAOBKO_01228	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IOHAOBKO_01229	8.56e-227	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOHAOBKO_01230	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
IOHAOBKO_01231	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOHAOBKO_01232	1.74e-223	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
IOHAOBKO_01233	2.25e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
IOHAOBKO_01234	6.9e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOHAOBKO_01235	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOHAOBKO_01236	1.08e-39	-	-	-	-	-	-	-	-
IOHAOBKO_01237	4.99e-274	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01238	1.55e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IOHAOBKO_01239	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOHAOBKO_01240	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOHAOBKO_01241	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IOHAOBKO_01242	5.24e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOHAOBKO_01243	1.66e-25	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01244	4.45e-120	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
IOHAOBKO_01245	1.67e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01246	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOHAOBKO_01247	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOHAOBKO_01248	2.95e-240	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
IOHAOBKO_01249	5.43e-229	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOHAOBKO_01250	2.86e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOHAOBKO_01251	2.06e-278	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
IOHAOBKO_01252	4.88e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOHAOBKO_01253	5.94e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
IOHAOBKO_01254	4.61e-223	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IOHAOBKO_01255	2e-205	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOHAOBKO_01256	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
IOHAOBKO_01257	1.61e-244	-	-	-	-	-	-	-	-
IOHAOBKO_01258	3.42e-297	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOHAOBKO_01259	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOHAOBKO_01260	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
IOHAOBKO_01261	4.92e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOHAOBKO_01262	2.29e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOHAOBKO_01263	7.54e-200	-	-	-	G	-	-	-	Fructosamine kinase
IOHAOBKO_01264	1.51e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOHAOBKO_01265	1.78e-168	-	-	-	S	-	-	-	PAC2 family
IOHAOBKO_01271	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOHAOBKO_01272	1.6e-144	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
IOHAOBKO_01273	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IOHAOBKO_01274	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IOHAOBKO_01275	1.19e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOHAOBKO_01276	2.48e-253	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOHAOBKO_01277	6.21e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
IOHAOBKO_01278	1.86e-129	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOHAOBKO_01279	4.18e-282	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOHAOBKO_01280	5.31e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOHAOBKO_01281	2.3e-295	-	-	-	-	-	-	-	-
IOHAOBKO_01282	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOHAOBKO_01283	3.55e-43	-	-	-	-	-	-	-	-
IOHAOBKO_01284	2.36e-175	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOHAOBKO_01285	9.06e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOHAOBKO_01286	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOHAOBKO_01288	8.84e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IOHAOBKO_01289	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOHAOBKO_01290	0.0	-	-	-	K	-	-	-	WYL domain
IOHAOBKO_01291	4.22e-70	-	-	-	-	-	-	-	-
IOHAOBKO_01292	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
IOHAOBKO_01293	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
IOHAOBKO_01294	6.16e-178	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOHAOBKO_01295	1.21e-48	-	-	-	-	-	-	-	-
IOHAOBKO_01296	3.89e-87	-	-	-	-	-	-	-	-
IOHAOBKO_01297	2.6e-142	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOHAOBKO_01298	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
IOHAOBKO_01299	6.51e-181	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOHAOBKO_01300	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
IOHAOBKO_01301	4.04e-217	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOHAOBKO_01302	3.69e-135	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOHAOBKO_01303	3.56e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
IOHAOBKO_01304	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
IOHAOBKO_01305	7.16e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
IOHAOBKO_01306	1.11e-239	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOHAOBKO_01307	1.03e-206	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOHAOBKO_01308	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOHAOBKO_01309	1.84e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
IOHAOBKO_01310	4.15e-196	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOHAOBKO_01311	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
IOHAOBKO_01313	6.97e-240	-	-	-	V	-	-	-	VanZ like family
IOHAOBKO_01314	2.85e-18	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
IOHAOBKO_01315	5e-42	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
IOHAOBKO_01316	3.57e-35	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
IOHAOBKO_01317	1.1e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_01318	3.88e-62	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOHAOBKO_01319	1.49e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
IOHAOBKO_01320	2.55e-65	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
IOHAOBKO_01322	1.16e-42	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01323	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01324	1.66e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_01325	1.47e-210	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOHAOBKO_01326	7.45e-181	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
IOHAOBKO_01327	2.77e-189	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
IOHAOBKO_01328	2.25e-300	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOHAOBKO_01329	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
IOHAOBKO_01330	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
IOHAOBKO_01331	0.0	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IOHAOBKO_01332	8.82e-141	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
IOHAOBKO_01333	1.38e-47	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOHAOBKO_01334	5.54e-127	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IOHAOBKO_01335	6.43e-284	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IOHAOBKO_01336	2.78e-34	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
IOHAOBKO_01337	9.92e-91	istB	-	-	L	-	-	-	IstB-like ATP binding protein
IOHAOBKO_01338	2.08e-75	-	-	-	L	-	-	-	IstB-like ATP binding protein
IOHAOBKO_01339	1.93e-210	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_01341	3.34e-30	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_01342	5.55e-169	istB	-	-	L	-	-	-	IstB-like ATP binding protein
IOHAOBKO_01343	2.43e-263	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_01344	2.38e-84	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_01345	3.45e-127	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
IOHAOBKO_01346	2.59e-25	-	-	-	S	-	-	-	AAA ATPase domain
IOHAOBKO_01347	2.28e-128	-	-	-	L	ko:K07485	-	ko00000	Transposase
IOHAOBKO_01348	1.98e-59	-	-	-	L	-	-	-	Transposase, Mutator family
IOHAOBKO_01349	4.55e-86	-	-	-	-	-	-	-	-
IOHAOBKO_01350	9.63e-109	-	-	-	-	-	-	-	-
IOHAOBKO_01351	9.99e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_01352	1.53e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
IOHAOBKO_01353	1.01e-187	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOHAOBKO_01354	8.22e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOHAOBKO_01355	6.89e-278	-	-	-	GK	-	-	-	ROK family
IOHAOBKO_01356	1.12e-203	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
IOHAOBKO_01357	0.0	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
IOHAOBKO_01358	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
IOHAOBKO_01359	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
IOHAOBKO_01360	7.98e-151	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
IOHAOBKO_01361	5.31e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_01362	9.29e-67	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOHAOBKO_01363	2.48e-276	-	-	-	L	-	-	-	Transposase, Mutator family
IOHAOBKO_01364	2.01e-68	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
IOHAOBKO_01365	2.66e-58	-	-	-	K	-	-	-	Addiction module
IOHAOBKO_01367	2.16e-103	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IOHAOBKO_01368	1.3e-183	-	-	-	P	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOHAOBKO_01369	7e-121	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
IOHAOBKO_01370	3.84e-156	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
IOHAOBKO_01371	7.88e-239	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	family 5
IOHAOBKO_01372	7.29e-26	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IOHAOBKO_01373	1.6e-83	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IOHAOBKO_01375	8.06e-298	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01376	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01377	1.84e-206	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01378	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
IOHAOBKO_01379	7.29e-220	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
IOHAOBKO_01380	3.27e-187	traX	-	-	S	-	-	-	TraX protein
IOHAOBKO_01381	5.58e-248	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_01382	3.71e-37	-	-	-	L	-	-	-	Helix-turn-helix domain
IOHAOBKO_01383	3.31e-228	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
IOHAOBKO_01384	2.87e-166	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
IOHAOBKO_01385	9.15e-188	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01386	1.28e-219	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IOHAOBKO_01387	4.18e-280	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
IOHAOBKO_01389	3.36e-196	-	2.7.8.12	-	S	ko:K09809	-	ko00000,ko01000	Glycosyl transferase family 2
IOHAOBKO_01390	6.16e-33	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IOHAOBKO_01396	9e-48	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
IOHAOBKO_01397	6.02e-37	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
IOHAOBKO_01398	5.82e-133	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
IOHAOBKO_01399	2.48e-16	-	-	-	S	-	-	-	Unextendable partial coding region
IOHAOBKO_01401	6e-244	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOHAOBKO_01403	6.86e-213	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOHAOBKO_01404	4.24e-78	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
IOHAOBKO_01405	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
IOHAOBKO_01406	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOHAOBKO_01407	2.49e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOHAOBKO_01408	2.45e-224	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
IOHAOBKO_01409	2.35e-133	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
IOHAOBKO_01410	5.43e-21	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
IOHAOBKO_01411	1.1e-141	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
IOHAOBKO_01412	7.57e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
IOHAOBKO_01413	1.57e-163	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
IOHAOBKO_01414	7.43e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IOHAOBKO_01415	1.69e-155	-	-	-	D	-	-	-	bacterial-type flagellum organization
IOHAOBKO_01416	2.43e-241	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
IOHAOBKO_01417	1.2e-93	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
IOHAOBKO_01418	3.27e-149	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
IOHAOBKO_01419	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
IOHAOBKO_01420	2.92e-75	-	-	-	U	-	-	-	TadE-like protein
IOHAOBKO_01421	3.01e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
IOHAOBKO_01422	1.09e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
IOHAOBKO_01423	2.69e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_01424	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
IOHAOBKO_01425	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOHAOBKO_01426	2.81e-37	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOHAOBKO_01427	7.89e-270	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOHAOBKO_01428	1.1e-90	-	-	-	V	-	-	-	Abi-like protein
IOHAOBKO_01429	1.31e-245	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IOHAOBKO_01430	6.3e-174	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
IOHAOBKO_01431	6.76e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
IOHAOBKO_01432	7.59e-269	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOHAOBKO_01433	2.83e-144	-	-	-	-	-	-	-	-
IOHAOBKO_01434	2.11e-221	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
IOHAOBKO_01435	2.48e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOHAOBKO_01436	1.2e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IOHAOBKO_01437	4.05e-204	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
IOHAOBKO_01438	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOHAOBKO_01439	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01440	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOHAOBKO_01441	2.39e-188	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01442	1.83e-231	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
IOHAOBKO_01443	3.54e-188	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOHAOBKO_01444	4.83e-17	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
IOHAOBKO_01445	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
IOHAOBKO_01446	1.84e-312	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_01447	3.99e-196	-	-	-	K	-	-	-	FCD
IOHAOBKO_01448	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IOHAOBKO_01449	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOHAOBKO_01450	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
IOHAOBKO_01451	2.87e-214	-	-	-	I	-	-	-	PAP2 superfamily
IOHAOBKO_01452	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOHAOBKO_01453	1.68e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOHAOBKO_01454	1.85e-265	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOHAOBKO_01455	5.22e-137	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_01456	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
IOHAOBKO_01457	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOHAOBKO_01458	5.95e-135	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IOHAOBKO_01459	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IOHAOBKO_01460	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
IOHAOBKO_01461	1.11e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
IOHAOBKO_01462	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
IOHAOBKO_01463	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01464	4.34e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
IOHAOBKO_01465	3.5e-205	-	-	-	-	-	-	-	-
IOHAOBKO_01466	3.62e-289	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IOHAOBKO_01467	1.24e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IOHAOBKO_01469	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOHAOBKO_01472	7e-38	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IOHAOBKO_01473	8.34e-28	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IOHAOBKO_01475	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
IOHAOBKO_01476	1.89e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
IOHAOBKO_01477	2.03e-291	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
IOHAOBKO_01478	6.04e-290	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IOHAOBKO_01479	5.7e-278	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOHAOBKO_01480	1.14e-186	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_01481	6.54e-100	-	-	-	S	-	-	-	FMN_bind
IOHAOBKO_01482	1.62e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01483	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOHAOBKO_01484	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOHAOBKO_01485	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IOHAOBKO_01486	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOHAOBKO_01487	3.54e-193	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
IOHAOBKO_01488	8.56e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
IOHAOBKO_01489	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOHAOBKO_01490	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IOHAOBKO_01492	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IOHAOBKO_01493	2.2e-251	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
IOHAOBKO_01494	4.13e-193	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_01495	1.69e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOHAOBKO_01496	1.12e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
IOHAOBKO_01497	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
IOHAOBKO_01498	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
IOHAOBKO_01499	4.25e-305	dinF	-	-	V	-	-	-	MatE
IOHAOBKO_01500	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOHAOBKO_01501	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
IOHAOBKO_01502	1.29e-180	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
IOHAOBKO_01503	1.91e-52	-	-	-	S	-	-	-	granule-associated protein
IOHAOBKO_01504	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
IOHAOBKO_01505	2.87e-89	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
IOHAOBKO_01506	1.39e-296	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
IOHAOBKO_01507	3.01e-197	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOHAOBKO_01508	3.31e-238	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOHAOBKO_01509	8.96e-212	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOHAOBKO_01510	3.3e-295	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
IOHAOBKO_01511	2.06e-182	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
IOHAOBKO_01512	9.3e-149	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01513	7.54e-186	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01514	6.93e-06	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
IOHAOBKO_01515	4.51e-148	-	-	-	K	-	-	-	WHG domain
IOHAOBKO_01516	1.75e-143	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
IOHAOBKO_01517	2.62e-29	-	-	-	-	-	-	-	-
IOHAOBKO_01518	4.53e-16	-	-	-	-	-	-	-	-
IOHAOBKO_01520	3.89e-212	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOHAOBKO_01521	1.08e-111	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
IOHAOBKO_01522	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOHAOBKO_01523	1.98e-18	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01524	1.84e-212	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IOHAOBKO_01528	2.97e-211	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IOHAOBKO_01529	1.15e-163	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOHAOBKO_01530	2.45e-29	-	-	-	-	-	-	-	-
IOHAOBKO_01531	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
IOHAOBKO_01532	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOHAOBKO_01533	1.92e-66	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IOHAOBKO_01534	8.17e-112	istB	-	-	L	-	-	-	IstB-like ATP binding protein
IOHAOBKO_01535	3.33e-217	-	-	-	G	-	-	-	Acyltransferase family
IOHAOBKO_01536	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IOHAOBKO_01537	6.83e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
IOHAOBKO_01538	3.01e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOHAOBKO_01539	2.08e-264	-	-	-	S	-	-	-	AAA ATPase domain
IOHAOBKO_01540	3.58e-300	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IOHAOBKO_01541	1.55e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IOHAOBKO_01542	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_01543	3.46e-157	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
IOHAOBKO_01546	4e-21	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_01547	3.64e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOHAOBKO_01548	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOHAOBKO_01549	3.42e-259	-	-	-	V	-	-	-	VanZ like family
IOHAOBKO_01550	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01551	2.81e-13	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
IOHAOBKO_01552	3.55e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IOHAOBKO_01553	6.05e-89	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
IOHAOBKO_01554	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOHAOBKO_01555	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOHAOBKO_01556	3.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
IOHAOBKO_01557	2.26e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOHAOBKO_01558	4.88e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOHAOBKO_01559	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOHAOBKO_01560	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IOHAOBKO_01561	2.15e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOHAOBKO_01562	2.94e-236	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
IOHAOBKO_01563	1.97e-119	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
IOHAOBKO_01564	3.56e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IOHAOBKO_01565	5.17e-223	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOHAOBKO_01566	3.33e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOHAOBKO_01567	2.45e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOHAOBKO_01568	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
IOHAOBKO_01569	0.0	-	-	-	-	-	-	-	-
IOHAOBKO_01570	5.27e-211	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
IOHAOBKO_01571	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
IOHAOBKO_01572	4.16e-143	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
IOHAOBKO_01573	2.47e-222	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOHAOBKO_01574	7.89e-216	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOHAOBKO_01575	6.72e-282	rpfB	-	-	S	ko:K21688	-	ko00000	G5
IOHAOBKO_01577	2.54e-181	-	-	-	O	-	-	-	Thioredoxin
IOHAOBKO_01578	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IOHAOBKO_01579	1.97e-143	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
IOHAOBKO_01580	4.57e-152	-	-	-	T	-	-	-	LytTr DNA-binding domain
IOHAOBKO_01581	2.82e-167	-	-	-	T	-	-	-	GHKL domain
IOHAOBKO_01582	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
IOHAOBKO_01583	1.03e-73	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
IOHAOBKO_01584	5.89e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
IOHAOBKO_01585	7.8e-156	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOHAOBKO_01586	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
IOHAOBKO_01587	6.17e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IOHAOBKO_01589	1.34e-56	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IOHAOBKO_01590	8.53e-115	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IOHAOBKO_01591	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOHAOBKO_01593	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOHAOBKO_01594	1.68e-274	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOHAOBKO_01595	1.66e-95	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOHAOBKO_01596	1.04e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IOHAOBKO_01597	3.12e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
IOHAOBKO_01598	7.15e-176	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
IOHAOBKO_01599	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOHAOBKO_01600	7.18e-31	-	-	-	L	-	-	-	Winged helix-turn helix
IOHAOBKO_01602	2.72e-231	-	-	-	-	-	-	-	-
IOHAOBKO_01603	4.32e-191	-	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
IOHAOBKO_01604	3.89e-223	rbsA	3.6.3.17	-	G	ko:K10441,ko:K10542,ko:K17215	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01605	6.91e-187	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
IOHAOBKO_01606	1.13e-166	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_01607	7.31e-22	tnp3521a2	-	-	L	-	-	-	Integrase core domain
IOHAOBKO_01608	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
IOHAOBKO_01609	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IOHAOBKO_01610	3.02e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOHAOBKO_01611	1.22e-175	-	-	-	-	-	-	-	-
IOHAOBKO_01612	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
IOHAOBKO_01613	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IOHAOBKO_01614	2.35e-210	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
IOHAOBKO_01615	3.08e-220	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOHAOBKO_01616	8.98e-27	-	-	-	-	-	-	-	-
IOHAOBKO_01617	5.1e-160	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IOHAOBKO_01618	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
IOHAOBKO_01619	1.14e-105	-	-	-	-	-	-	-	-
IOHAOBKO_01620	1.43e-142	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
IOHAOBKO_01621	2.47e-193	-	-	-	-	-	-	-	-
IOHAOBKO_01622	6.17e-189	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
IOHAOBKO_01623	1.02e-158	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOHAOBKO_01624	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
IOHAOBKO_01625	1.77e-102	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOHAOBKO_01626	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
IOHAOBKO_01627	8.97e-294	-	-	-	GK	-	-	-	ROK family
IOHAOBKO_01628	3.13e-310	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01629	5.6e-206	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01630	7.15e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01632	7.85e-290	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IOHAOBKO_01633	2.11e-98	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
IOHAOBKO_01635	4.15e-134	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
IOHAOBKO_01640	8.55e-85	-	-	-	L	-	-	-	Integrase core domain
IOHAOBKO_01641	1.22e-61	-	-	-	L	-	-	-	Integrase core domain
IOHAOBKO_01642	1.93e-61	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IOHAOBKO_01643	9.49e-178	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOHAOBKO_01644	1.14e-68	-	-	-	-	-	-	-	-
IOHAOBKO_01645	2.24e-238	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOHAOBKO_01646	1.41e-243	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOHAOBKO_01647	5.06e-234	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOHAOBKO_01648	4.92e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOHAOBKO_01649	2.03e-251	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOHAOBKO_01650	1.1e-172	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
IOHAOBKO_01651	4.29e-08	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
IOHAOBKO_01652	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOHAOBKO_01653	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
IOHAOBKO_01654	1.57e-80	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOHAOBKO_01655	2.1e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IOHAOBKO_01656	7.82e-183	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
IOHAOBKO_01657	1.34e-191	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
IOHAOBKO_01658	1.93e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOHAOBKO_01659	1.11e-150	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOHAOBKO_01660	4.33e-196	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
IOHAOBKO_01661	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOHAOBKO_01662	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IOHAOBKO_01663	1.07e-207	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
IOHAOBKO_01664	1.92e-301	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
IOHAOBKO_01665	3.49e-24	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
IOHAOBKO_01666	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOHAOBKO_01667	1.49e-176	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01668	4.2e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
IOHAOBKO_01669	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
IOHAOBKO_01670	5.73e-101	-	-	-	-	-	-	-	-
IOHAOBKO_01671	1.41e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IOHAOBKO_01672	1.36e-242	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
IOHAOBKO_01673	9.63e-56	-	-	-	-	-	-	-	-
IOHAOBKO_01674	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IOHAOBKO_01675	7.44e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_01676	2.96e-242	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
IOHAOBKO_01677	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IOHAOBKO_01678	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01679	2.12e-228	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOHAOBKO_01680	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
IOHAOBKO_01681	1.13e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
IOHAOBKO_01682	3.99e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
IOHAOBKO_01683	2.99e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
IOHAOBKO_01684	1.86e-306	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOHAOBKO_01685	5.29e-127	-	-	-	-	-	-	-	-
IOHAOBKO_01686	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IOHAOBKO_01687	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOHAOBKO_01688	6.43e-153	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01689	1.86e-105	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
IOHAOBKO_01690	2.33e-174	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IOHAOBKO_01691	3.21e-211	-	-	-	EG	-	-	-	EamA-like transporter family
IOHAOBKO_01692	6.23e-186	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
IOHAOBKO_01693	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOHAOBKO_01694	3.38e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOHAOBKO_01695	3.87e-193	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IOHAOBKO_01696	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
IOHAOBKO_01697	4.89e-152	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOHAOBKO_01698	1.54e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOHAOBKO_01699	2.3e-101	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOHAOBKO_01700	9.29e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
IOHAOBKO_01701	1.29e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOHAOBKO_01702	1.84e-132	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IOHAOBKO_01703	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOHAOBKO_01704	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOHAOBKO_01705	5.12e-243	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOHAOBKO_01706	1.89e-158	-	-	-	-	-	-	-	-
IOHAOBKO_01707	2.4e-169	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
IOHAOBKO_01708	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
IOHAOBKO_01709	1.95e-250	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOHAOBKO_01710	2.58e-141	-	-	-	-	-	-	-	-
IOHAOBKO_01711	2.4e-248	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOHAOBKO_01712	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
IOHAOBKO_01713	1.25e-284	-	-	-	G	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01714	1.17e-218	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOHAOBKO_01715	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IOHAOBKO_01718	3.14e-27	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOHAOBKO_01719	7.07e-127	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01720	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
IOHAOBKO_01721	7.3e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
IOHAOBKO_01722	2.05e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
IOHAOBKO_01723	4.95e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
IOHAOBKO_01724	2.39e-108	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IOHAOBKO_01725	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOHAOBKO_01726	8.07e-133	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOHAOBKO_01727	1.31e-98	-	-	-	-	-	-	-	-
IOHAOBKO_01729	7.8e-299	-	-	-	S	-	-	-	HipA-like C-terminal domain
IOHAOBKO_01730	6.44e-64	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
IOHAOBKO_01732	1.53e-35	-	-	-	-	-	-	-	-
IOHAOBKO_01733	3.41e-183	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IOHAOBKO_01734	9.5e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
IOHAOBKO_01735	7.21e-205	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01736	1.99e-207	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01737	2.11e-309	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01738	6.09e-276	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_01739	4.86e-29	-	-	-	-	-	-	-	-
IOHAOBKO_01741	2.11e-77	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
IOHAOBKO_01742	6.07e-27	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
IOHAOBKO_01743	3.9e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOHAOBKO_01744	2.83e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
IOHAOBKO_01745	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
IOHAOBKO_01746	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
IOHAOBKO_01747	4e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IOHAOBKO_01748	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
IOHAOBKO_01752	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOHAOBKO_01753	1.32e-183	-	-	-	-	-	-	-	-
IOHAOBKO_01754	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOHAOBKO_01755	2.06e-78	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
IOHAOBKO_01756	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
IOHAOBKO_01757	1.92e-120	-	-	-	NO	-	-	-	SAF
IOHAOBKO_01758	8.07e-34	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
IOHAOBKO_01759	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
IOHAOBKO_01760	2.22e-273	-	-	-	T	-	-	-	Forkhead associated domain
IOHAOBKO_01761	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOHAOBKO_01762	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOHAOBKO_01763	5.66e-186	-	-	-	S	-	-	-	alpha beta
IOHAOBKO_01764	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
IOHAOBKO_01765	1.57e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOHAOBKO_01766	1.86e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IOHAOBKO_01767	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOHAOBKO_01768	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
IOHAOBKO_01769	1.5e-182	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IOHAOBKO_01770	1.14e-276	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
IOHAOBKO_01771	7.6e-305	-	-	-	EGP	-	-	-	Sugar (and other) transporter
IOHAOBKO_01772	2.11e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOHAOBKO_01773	9.45e-300	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOHAOBKO_01774	2.3e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOHAOBKO_01775	1.97e-111	-	-	-	G	ko:K12112	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001	YhcH YjgK YiaL family protein
IOHAOBKO_01776	0.0	-	3.2.1.23	-	G	ko:K12111	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01777	6.14e-147	pgmB	5.4.2.6	-	S	ko:K01838,ko:K04844	ko00500,map00500	ko00000,ko00001,ko01000	phosphonoacetaldehyde hydrolase activity
IOHAOBKO_01778	6.58e-200	-	-	-	EG	-	-	-	EamA-like transporter family
IOHAOBKO_01779	0.0	kojP	2.4.1.230, 2.4.1.64	GH65	G	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
IOHAOBKO_01780	1.51e-195	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01781	5.76e-216	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01782	2.04e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01783	1.59e-241	-	-	-	K	-	-	-	Periplasmic binding protein domain
IOHAOBKO_01784	1.41e-127	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
IOHAOBKO_01785	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOHAOBKO_01786	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOHAOBKO_01787	6.94e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
IOHAOBKO_01788	6.14e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOHAOBKO_01789	1.56e-192	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOHAOBKO_01790	5.84e-252	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
IOHAOBKO_01791	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
IOHAOBKO_01792	2.38e-225	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOHAOBKO_01793	1.17e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
IOHAOBKO_01794	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
IOHAOBKO_01795	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
IOHAOBKO_01796	2.02e-246	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
IOHAOBKO_01797	7.26e-302	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
IOHAOBKO_01798	2.28e-168	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOHAOBKO_01799	3.59e-82	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
IOHAOBKO_01800	2.07e-71	-	-	-	L	-	-	-	RelB antitoxin
IOHAOBKO_01801	1.49e-30	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
IOHAOBKO_01802	1.41e-244	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOHAOBKO_01803	1.28e-12	-	-	-	-	-	-	-	-
IOHAOBKO_01807	1.01e-58	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
IOHAOBKO_01808	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
IOHAOBKO_01809	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
IOHAOBKO_01810	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
IOHAOBKO_01812	1.6e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOHAOBKO_01813	3.7e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
IOHAOBKO_01814	0.0	-	-	-	-	-	-	-	-
IOHAOBKO_01815	7.54e-211	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IOHAOBKO_01816	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOHAOBKO_01817	2.9e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOHAOBKO_01818	4.78e-58	istB	-	-	L	-	-	-	IstB-like ATP binding protein
IOHAOBKO_01819	6.32e-55	-	-	-	-	-	-	-	-
IOHAOBKO_01820	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOHAOBKO_01821	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
IOHAOBKO_01822	1.05e-177	nfrA	-	-	C	-	-	-	Nitroreductase family
IOHAOBKO_01823	6.43e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
IOHAOBKO_01824	1.29e-132	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
IOHAOBKO_01825	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01826	1.4e-235	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_01827	3.3e-200	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01828	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IOHAOBKO_01829	9.49e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOHAOBKO_01830	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
IOHAOBKO_01831	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOHAOBKO_01832	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IOHAOBKO_01833	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IOHAOBKO_01834	8.11e-121	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOHAOBKO_01835	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_01836	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
IOHAOBKO_01837	4.14e-229	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOHAOBKO_01838	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
IOHAOBKO_01840	8.72e-235	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOHAOBKO_01841	5.33e-156	-	-	-	-	-	-	-	-
IOHAOBKO_01842	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOHAOBKO_01843	2.02e-62	-	-	-	-	-	-	-	-
IOHAOBKO_01844	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IOHAOBKO_01845	3.53e-228	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01846	8.61e-227	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
IOHAOBKO_01847	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOHAOBKO_01848	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IOHAOBKO_01849	2.41e-44	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IOHAOBKO_01850	1.48e-71	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IOHAOBKO_01851	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
IOHAOBKO_01852	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
IOHAOBKO_01853	5.81e-249	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
IOHAOBKO_01854	9.99e-309	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOHAOBKO_01855	3.14e-227	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01856	3.67e-196	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOHAOBKO_01857	7.96e-243	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
IOHAOBKO_01858	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
IOHAOBKO_01859	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
IOHAOBKO_01860	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOHAOBKO_01861	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOHAOBKO_01862	1.92e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
IOHAOBKO_01863	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IOHAOBKO_01864	4.08e-204	-	-	-	S	-	-	-	Glutamine amidotransferase domain
IOHAOBKO_01865	1.01e-179	-	-	-	T	ko:K06950	-	ko00000	HD domain
IOHAOBKO_01866	1.88e-243	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOHAOBKO_01867	0.0	-	-	-	V	-	-	-	ABC transporter permease
IOHAOBKO_01868	1.61e-309	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
IOHAOBKO_01869	3.42e-270	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IOHAOBKO_01870	6.77e-219	-	-	-	M	-	-	-	Glycosyl transferase family 2
IOHAOBKO_01871	0.0	-	-	-	-	-	-	-	-
IOHAOBKO_01872	1.39e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOHAOBKO_01873	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOHAOBKO_01874	4.97e-218	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOHAOBKO_01875	7.29e-231	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOHAOBKO_01876	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
IOHAOBKO_01877	1.44e-192	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
IOHAOBKO_01878	1.26e-299	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOHAOBKO_01879	0.0	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IOHAOBKO_01880	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOHAOBKO_01881	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
IOHAOBKO_01884	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
IOHAOBKO_01885	7.05e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
IOHAOBKO_01886	1.09e-226	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOHAOBKO_01887	0.0	-	-	-	S	-	-	-	AI-2E family transporter
IOHAOBKO_01888	5.88e-297	-	-	-	M	-	-	-	Glycosyl transferase family 21
IOHAOBKO_01889	4.06e-246	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01890	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IOHAOBKO_01891	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
IOHAOBKO_01892	1.78e-263	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOHAOBKO_01893	2.66e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOHAOBKO_01894	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOHAOBKO_01896	7.27e-139	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IOHAOBKO_01897	3.57e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOHAOBKO_01898	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOHAOBKO_01899	2.23e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
IOHAOBKO_01900	1.48e-216	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
IOHAOBKO_01901	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
IOHAOBKO_01902	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOHAOBKO_01904	2.48e-227	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IOHAOBKO_01905	8.08e-117	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IOHAOBKO_01906	9.34e-23	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
IOHAOBKO_01907	7.01e-210	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
IOHAOBKO_01908	1.76e-94	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOHAOBKO_01909	2.4e-187	-	-	-	-	-	-	-	-
IOHAOBKO_01910	1.2e-90	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
IOHAOBKO_01912	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IOHAOBKO_01913	5.78e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOHAOBKO_01914	2.39e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOHAOBKO_01915	5.37e-271	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOHAOBKO_01916	1.08e-196	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOHAOBKO_01917	1.25e-240	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOHAOBKO_01918	2.73e-205	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
IOHAOBKO_01919	4.8e-159	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOHAOBKO_01920	2.92e-153	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
IOHAOBKO_01921	9.69e-275	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
IOHAOBKO_01922	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOHAOBKO_01923	3.86e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IOHAOBKO_01924	0.0	-	-	-	L	-	-	-	PIF1-like helicase
IOHAOBKO_01925	0.0	-	-	-	S	ko:K06990	-	ko00000,ko04812	AMMECR1
IOHAOBKO_01926	2.78e-254	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
IOHAOBKO_01927	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOHAOBKO_01928	2.29e-152	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
IOHAOBKO_01929	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
IOHAOBKO_01930	2.29e-196	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IOHAOBKO_01931	1.25e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOHAOBKO_01932	6.38e-315	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
IOHAOBKO_01933	7.18e-218	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
IOHAOBKO_01934	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
IOHAOBKO_01935	3.54e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_01936	1.24e-114	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IOHAOBKO_01937	2.14e-257	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
IOHAOBKO_01938	6.37e-299	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
IOHAOBKO_01939	2.39e-228	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
IOHAOBKO_01940	1.21e-268	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
IOHAOBKO_01942	7.41e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
IOHAOBKO_01943	1.35e-87	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOHAOBKO_01944	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
IOHAOBKO_01945	3.71e-122	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
IOHAOBKO_01946	1.02e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOHAOBKO_01947	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOHAOBKO_01948	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
IOHAOBKO_01949	2.3e-174	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOHAOBKO_01950	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
IOHAOBKO_01951	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
IOHAOBKO_01952	5.49e-183	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOHAOBKO_01953	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
IOHAOBKO_01955	5.86e-61	-	-	-	S	-	-	-	Nucleotidyltransferase domain
IOHAOBKO_01956	1.26e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
IOHAOBKO_01957	3.88e-308	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IOHAOBKO_01958	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IOHAOBKO_01959	1.6e-220	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOHAOBKO_01960	0.0	-	-	-	M	-	-	-	domain protein
IOHAOBKO_01961	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
IOHAOBKO_01963	1.84e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
IOHAOBKO_01964	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
IOHAOBKO_01965	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOHAOBKO_01966	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOHAOBKO_01967	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
IOHAOBKO_01968	5.98e-243	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_01969	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
IOHAOBKO_01970	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
IOHAOBKO_01971	1.15e-257	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOHAOBKO_01972	1.02e-63	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IOHAOBKO_01973	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOHAOBKO_01974	1.24e-200	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOHAOBKO_01975	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
IOHAOBKO_01976	2.27e-307	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOHAOBKO_01977	1e-248	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
IOHAOBKO_01978	2.17e-214	-	-	-	EG	-	-	-	EamA-like transporter family
IOHAOBKO_01980	9.22e-217	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IOHAOBKO_01981	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
IOHAOBKO_01982	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
IOHAOBKO_01983	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
IOHAOBKO_01984	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOHAOBKO_01986	6.07e-192	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
IOHAOBKO_01987	1.65e-115	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
IOHAOBKO_01988	1.23e-69	-	-	-	S	-	-	-	Putative heavy-metal-binding
IOHAOBKO_01989	1.1e-208	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IOHAOBKO_01990	1.91e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4928)
IOHAOBKO_01991	1.24e-215	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
IOHAOBKO_01992	8.49e-313	-	-	-	L	-	-	-	Z1 domain
IOHAOBKO_01993	6.73e-40	-	-	-	S	-	-	-	Putative PD-(D/E)XK family member, (DUF4420)
IOHAOBKO_01995	1.62e-295	-	-	-	S	-	-	-	AIPR protein
IOHAOBKO_01996	8.56e-217	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
IOHAOBKO_01997	2.82e-210	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOHAOBKO_01998	5.4e-252	-	-	-	S	-	-	-	Fic/DOC family
IOHAOBKO_01999	1.01e-168	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IOHAOBKO_02000	5.21e-256	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOHAOBKO_02001	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
IOHAOBKO_02002	0.0	-	-	-	S	-	-	-	Putative esterase
IOHAOBKO_02003	7.42e-28	-	-	-	-	-	-	-	-
IOHAOBKO_02004	3.74e-218	-	-	-	EG	-	-	-	EamA-like transporter family
IOHAOBKO_02005	2.45e-119	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
IOHAOBKO_02006	1.08e-270	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
IOHAOBKO_02007	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
IOHAOBKO_02008	8.7e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
IOHAOBKO_02009	8.95e-105	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
IOHAOBKO_02010	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
IOHAOBKO_02011	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOHAOBKO_02012	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IOHAOBKO_02013	1.54e-221	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOHAOBKO_02014	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IOHAOBKO_02015	9.12e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
IOHAOBKO_02016	3.94e-292	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOHAOBKO_02017	1.56e-162	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
IOHAOBKO_02018	1.98e-100	crgA	-	-	D	-	-	-	Involved in cell division
IOHAOBKO_02019	2.82e-177	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IOHAOBKO_02020	2.96e-47	-	-	-	-	-	-	-	-
IOHAOBKO_02021	1.18e-52	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties