ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KNFDGABE_00001 2.31e-52 - - - S - - - Protein of unknown function (DUF1797)
KNFDGABE_00002 3.26e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNFDGABE_00003 1.13e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KNFDGABE_00004 5.17e-290 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KNFDGABE_00005 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNFDGABE_00006 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KNFDGABE_00007 1.38e-37 - - - - - - - -
KNFDGABE_00008 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KNFDGABE_00009 1.56e-130 - - - S - - - Pfam:DUF3816
KNFDGABE_00010 9.48e-183 - - - G - - - MucBP domain
KNFDGABE_00011 7.22e-142 - - - - - - - -
KNFDGABE_00012 1.99e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00013 7.18e-86 - - - K - - - Transcriptional regulator, GntR family
KNFDGABE_00014 1.53e-64 - - - M - - - Peptidase_C39 like family
KNFDGABE_00015 5.01e-81 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KNFDGABE_00016 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KNFDGABE_00017 9.71e-301 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KNFDGABE_00018 4.18e-202 - - - S - - - Psort location CytoplasmicMembrane, score
KNFDGABE_00019 1.19e-228 yueF - - S - - - AI-2E family transporter
KNFDGABE_00020 4.9e-95 - - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 dextransucrase activity
KNFDGABE_00022 7.51e-59 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KNFDGABE_00023 1.04e-191 - - - M - - - Glycosyltransferase like family 2
KNFDGABE_00024 7.68e-42 - - - - - - - -
KNFDGABE_00025 1.74e-153 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
KNFDGABE_00026 2.53e-53 - - - M - - - KxYKxGKxW signal domain protein
KNFDGABE_00028 1.57e-105 - - - S - - - Psort location CytoplasmicMembrane, score
KNFDGABE_00029 1.63e-108 - - - M - - - biosynthesis protein
KNFDGABE_00030 1.23e-234 cps3F - - - - - - -
KNFDGABE_00031 4.45e-127 - - - S - - - enterobacterial common antigen metabolic process
KNFDGABE_00033 1.49e-86 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
KNFDGABE_00034 2.88e-167 - - - M - - - transferase activity, transferring glycosyl groups
KNFDGABE_00035 8.06e-190 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
KNFDGABE_00036 6.99e-304 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KNFDGABE_00037 1.68e-276 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KNFDGABE_00038 2.32e-152 - - - M - - - Bacterial sugar transferase
KNFDGABE_00039 1.33e-223 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KNFDGABE_00040 2.33e-190 cps1D - - M - - - Domain of unknown function (DUF4422)
KNFDGABE_00041 1.22e-176 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KNFDGABE_00042 2.53e-42 - - - - - - - -
KNFDGABE_00043 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
KNFDGABE_00044 2.13e-198 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KNFDGABE_00045 0.0 potE - - E - - - Amino Acid
KNFDGABE_00046 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KNFDGABE_00047 2.8e-280 arcT - - E - - - Aminotransferase
KNFDGABE_00048 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
KNFDGABE_00049 6.68e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KNFDGABE_00050 7.02e-88 gtcA - - S - - - Teichoic acid glycosylation protein
KNFDGABE_00051 1.73e-73 - - - - - - - -
KNFDGABE_00052 1.21e-290 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KNFDGABE_00053 1.41e-79 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KNFDGABE_00054 3.46e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KNFDGABE_00056 2.32e-298 yfmL - - L - - - DEAD DEAH box helicase
KNFDGABE_00057 5.34e-245 mocA - - S - - - Oxidoreductase
KNFDGABE_00058 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
KNFDGABE_00059 7.24e-136 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KNFDGABE_00060 9.2e-214 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KNFDGABE_00061 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KNFDGABE_00062 1.16e-239 - - - S - - - Protein of unknown function (DUF3114)
KNFDGABE_00063 4.36e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
KNFDGABE_00064 3.21e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KNFDGABE_00065 7.95e-255 - - - P - - - Major Facilitator Superfamily
KNFDGABE_00066 1.55e-26 - - - - - - - -
KNFDGABE_00067 2.89e-100 - - - K - - - LytTr DNA-binding domain
KNFDGABE_00068 2.54e-96 - - - S - - - Protein of unknown function (DUF3021)
KNFDGABE_00069 3.35e-216 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
KNFDGABE_00070 2.16e-108 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
KNFDGABE_00071 3.87e-161 pnb - - C - - - nitroreductase
KNFDGABE_00072 2.12e-119 - - - - - - - -
KNFDGABE_00073 2.67e-106 yvbK - - K - - - GNAT family
KNFDGABE_00074 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
KNFDGABE_00075 6.26e-269 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KNFDGABE_00076 3.53e-44 - - - L - - - Winged helix-turn helix
KNFDGABE_00077 4.84e-21 ung2 - - L - - - Uracil-DNA glycosylase
KNFDGABE_00078 3.26e-144 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
KNFDGABE_00079 8.67e-122 dpsB - - P - - - Belongs to the Dps family
KNFDGABE_00080 1.35e-46 - - - C - - - Heavy-metal-associated domain
KNFDGABE_00081 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
KNFDGABE_00082 1.11e-110 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KNFDGABE_00083 9.81e-212 - - - L - - - PFAM Integrase catalytic region
KNFDGABE_00084 3.13e-61 - - - - - - - -
KNFDGABE_00085 3.18e-143 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_00086 1.4e-38 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_00087 6.79e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
KNFDGABE_00088 5.95e-96 - - - K - - - LytTr DNA-binding domain
KNFDGABE_00089 9.77e-80 - - - S - - - Protein of unknown function (DUF3021)
KNFDGABE_00090 2.6e-208 - - - L - - - Plasmid pRiA4b ORF-3-like protein
KNFDGABE_00091 2.7e-38 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNFDGABE_00092 7.71e-171 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNFDGABE_00093 8.32e-77 - 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 Domain of unknown function DUF83
KNFDGABE_00094 4.97e-239 - - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
KNFDGABE_00095 2.54e-90 - - - L ko:K19090 - ko00000,ko02048 CRISPR-associated protein Cas5
KNFDGABE_00096 5.86e-134 - - - L ko:K19075 - ko00000,ko02048 CRISPR-associated negative auto-regulator DevR/Csa2
KNFDGABE_00097 3e-77 - - - S ko:K19088 - ko00000,ko02048 CRISPR-associated protein (Cas_CXXC_CXXC)
KNFDGABE_00098 2.23e-15 - - - S ko:K19088 - ko00000,ko02048 CRISPR-associated protein (Cas_CXXC_CXXC)
KNFDGABE_00099 4.81e-65 - - - L ko:K19091 - ko00000,ko01000,ko02048 CRISPR associated protein Cas6
KNFDGABE_00100 0.0 - - - L - - - Helicase C-terminal domain protein
KNFDGABE_00101 2.29e-60 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KNFDGABE_00102 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNFDGABE_00103 5.72e-239 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
KNFDGABE_00104 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNFDGABE_00105 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KNFDGABE_00106 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNFDGABE_00107 1.11e-260 camS - - S - - - sex pheromone
KNFDGABE_00108 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNFDGABE_00109 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KNFDGABE_00110 4.61e-272 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KNFDGABE_00111 2.26e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KNFDGABE_00112 5.09e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
KNFDGABE_00113 5.21e-179 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
KNFDGABE_00114 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KNFDGABE_00115 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNFDGABE_00116 3.03e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KNFDGABE_00117 8.27e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNFDGABE_00118 2.49e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNFDGABE_00119 3.14e-189 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNFDGABE_00120 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KNFDGABE_00121 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNFDGABE_00122 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KNFDGABE_00123 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KNFDGABE_00124 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KNFDGABE_00125 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNFDGABE_00126 1.51e-159 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KNFDGABE_00127 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KNFDGABE_00128 1.22e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KNFDGABE_00129 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KNFDGABE_00130 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNFDGABE_00131 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNFDGABE_00132 8.7e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNFDGABE_00133 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNFDGABE_00134 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNFDGABE_00135 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNFDGABE_00136 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNFDGABE_00137 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNFDGABE_00138 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNFDGABE_00139 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KNFDGABE_00140 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNFDGABE_00141 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNFDGABE_00142 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNFDGABE_00143 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KNFDGABE_00144 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNFDGABE_00145 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KNFDGABE_00146 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KNFDGABE_00147 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KNFDGABE_00148 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KNFDGABE_00149 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNFDGABE_00150 2.4e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KNFDGABE_00151 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNFDGABE_00152 4.26e-148 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
KNFDGABE_00153 1.29e-260 - - - - - - - -
KNFDGABE_00154 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNFDGABE_00155 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNFDGABE_00156 5.99e-143 - - - K - - - Bacterial regulatory proteins, tetR family
KNFDGABE_00157 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KNFDGABE_00158 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KNFDGABE_00159 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KNFDGABE_00160 2.3e-229 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
KNFDGABE_00166 9.09e-149 dgk2 - - F - - - deoxynucleoside kinase
KNFDGABE_00167 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
KNFDGABE_00168 2.34e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KNFDGABE_00169 1.33e-151 - - - I - - - phosphatase
KNFDGABE_00170 6.11e-106 - - - S - - - Threonine/Serine exporter, ThrE
KNFDGABE_00171 5.75e-164 - - - S - - - Putative threonine/serine exporter
KNFDGABE_00172 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KNFDGABE_00173 5.46e-160 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
KNFDGABE_00174 4.92e-213 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KNFDGABE_00175 1.27e-152 - - - S - - - membrane
KNFDGABE_00176 2.34e-142 - - - S - - - VIT family
KNFDGABE_00177 2.79e-107 - - - T - - - Belongs to the universal stress protein A family
KNFDGABE_00178 2.8e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00179 3.85e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_00180 4.3e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KNFDGABE_00181 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KNFDGABE_00182 1.83e-278 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KNFDGABE_00183 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNFDGABE_00184 4.03e-75 - - - - - - - -
KNFDGABE_00185 5.33e-98 - - - K - - - MerR HTH family regulatory protein
KNFDGABE_00186 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
KNFDGABE_00187 6.68e-154 - - - S - - - Domain of unknown function (DUF4811)
KNFDGABE_00188 1.59e-210 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KNFDGABE_00190 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNFDGABE_00191 6.46e-121 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KNFDGABE_00192 5.3e-239 - - - I - - - Alpha beta
KNFDGABE_00193 0.0 qacA - - EGP - - - Major Facilitator
KNFDGABE_00194 3.16e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
KNFDGABE_00195 0.0 - - - S - - - Putative threonine/serine exporter
KNFDGABE_00196 5.08e-205 - - - K - - - LysR family
KNFDGABE_00197 2.71e-143 - - - I - - - Alpha/beta hydrolase family
KNFDGABE_00198 2.72e-194 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KNFDGABE_00199 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
KNFDGABE_00200 3.29e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
KNFDGABE_00201 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
KNFDGABE_00202 2.31e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KNFDGABE_00203 9.44e-223 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
KNFDGABE_00204 2.15e-158 citR - - K - - - sugar-binding domain protein
KNFDGABE_00205 7.5e-217 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KNFDGABE_00206 7.33e-167 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KNFDGABE_00207 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KNFDGABE_00208 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KNFDGABE_00209 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
KNFDGABE_00210 3.38e-201 mleR - - K - - - LysR family
KNFDGABE_00211 1.17e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNFDGABE_00212 1.35e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
KNFDGABE_00213 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
KNFDGABE_00214 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
KNFDGABE_00217 6.92e-31 - - - - - - - -
KNFDGABE_00218 8.65e-254 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KNFDGABE_00219 5.36e-97 - - - - - - - -
KNFDGABE_00220 5.17e-290 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KNFDGABE_00221 2.77e-178 - - - V - - - Beta-lactamase enzyme family
KNFDGABE_00222 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
KNFDGABE_00223 2.11e-273 - - - EGP - - - Transporter, major facilitator family protein
KNFDGABE_00224 0.0 arcT - - E - - - Dipeptidase
KNFDGABE_00225 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
KNFDGABE_00226 1.05e-227 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
KNFDGABE_00227 3.4e-215 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KNFDGABE_00228 3.17e-175 - - - I - - - alpha/beta hydrolase fold
KNFDGABE_00229 2.04e-230 - - - S - - - Conserved hypothetical protein 698
KNFDGABE_00230 2.14e-123 - - - S - - - NADPH-dependent FMN reductase
KNFDGABE_00231 3.23e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KNFDGABE_00232 9.01e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KNFDGABE_00233 7.69e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KNFDGABE_00234 3.97e-82 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KNFDGABE_00236 2.82e-71 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KNFDGABE_00242 7.87e-113 - - - Q - - - Methyltransferase
KNFDGABE_00243 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
KNFDGABE_00244 9.2e-303 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
KNFDGABE_00245 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KNFDGABE_00246 1.56e-178 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KNFDGABE_00247 5.69e-283 - - - G - - - Glycosyl hydrolases family 8
KNFDGABE_00248 1.18e-308 - - - M - - - Glycosyl transferase
KNFDGABE_00249 2.12e-193 - - - - - - - -
KNFDGABE_00250 3.02e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KNFDGABE_00251 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNFDGABE_00252 2.58e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
KNFDGABE_00253 1.37e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KNFDGABE_00254 4.19e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KNFDGABE_00255 2.14e-172 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
KNFDGABE_00256 6.63e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_00257 2.86e-184 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KNFDGABE_00258 1.11e-236 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
KNFDGABE_00259 4.23e-212 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KNFDGABE_00260 1.4e-145 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KNFDGABE_00261 1.45e-170 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KNFDGABE_00262 3.08e-102 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KNFDGABE_00263 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
KNFDGABE_00264 6.94e-92 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
KNFDGABE_00265 3.71e-64 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
KNFDGABE_00266 8.81e-129 - - - S - - - AmiS/UreI family transporter
KNFDGABE_00267 3.75e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KNFDGABE_00269 9.9e-240 - - - - - - - -
KNFDGABE_00270 9.45e-126 - - - K - - - acetyltransferase
KNFDGABE_00271 4.91e-28 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KNFDGABE_00272 1.06e-129 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KNFDGABE_00273 1.22e-289 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KNFDGABE_00274 2.09e-100 - - - L ko:K07491 - ko00000 Transposase IS200 like
KNFDGABE_00275 3.75e-226 - - - - - - - -
KNFDGABE_00276 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNFDGABE_00277 1.26e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KNFDGABE_00278 1.88e-34 - - - M - - - LPXTG-motif cell wall anchor domain protein
KNFDGABE_00279 2.79e-145 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KNFDGABE_00280 4.67e-62 azlD - - E - - - Branched-chain amino acid transport
KNFDGABE_00281 1.02e-11 - - - - - - - -
KNFDGABE_00282 2.02e-30 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KNFDGABE_00283 2.66e-106 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00284 4.22e-50 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
KNFDGABE_00285 0.0 - - - S - - - amidohydrolase
KNFDGABE_00286 2.65e-212 - - - S - - - reductase
KNFDGABE_00287 1.04e-119 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
KNFDGABE_00288 1.72e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KNFDGABE_00289 1.81e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
KNFDGABE_00290 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNFDGABE_00291 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KNFDGABE_00292 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KNFDGABE_00293 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNFDGABE_00294 3.1e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
KNFDGABE_00295 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNFDGABE_00296 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KNFDGABE_00297 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KNFDGABE_00298 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNFDGABE_00299 4.91e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KNFDGABE_00300 6.33e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
KNFDGABE_00301 2.95e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNFDGABE_00302 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNFDGABE_00303 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNFDGABE_00304 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KNFDGABE_00305 1.46e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNFDGABE_00306 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNFDGABE_00307 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KNFDGABE_00308 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KNFDGABE_00309 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KNFDGABE_00310 4.58e-270 yttB - - EGP - - - Major Facilitator
KNFDGABE_00311 2.21e-80 - - - - - - - -
KNFDGABE_00312 2.17e-209 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
KNFDGABE_00313 1.67e-128 - - - K - - - DNA-binding helix-turn-helix protein
KNFDGABE_00315 1.88e-96 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
KNFDGABE_00316 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KNFDGABE_00318 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KNFDGABE_00319 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNFDGABE_00320 1.14e-313 yycH - - S - - - YycH protein
KNFDGABE_00321 4.13e-192 yycI - - S - - - YycH protein
KNFDGABE_00322 3.06e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
KNFDGABE_00323 1.31e-286 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
KNFDGABE_00324 2.18e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
KNFDGABE_00325 3.65e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KNFDGABE_00326 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KNFDGABE_00328 9.06e-125 - - - S - - - reductase
KNFDGABE_00329 6.23e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
KNFDGABE_00330 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KNFDGABE_00331 1.46e-190 - - - E - - - Glyoxalase-like domain
KNFDGABE_00332 2.91e-187 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNFDGABE_00333 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KNFDGABE_00334 6.76e-199 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNFDGABE_00335 3.28e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KNFDGABE_00336 1.6e-271 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KNFDGABE_00337 5.55e-67 - - - - - - - -
KNFDGABE_00338 3.31e-61 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KNFDGABE_00339 0.0 - - - S - - - Putative peptidoglycan binding domain
KNFDGABE_00343 1.42e-224 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KNFDGABE_00344 9.67e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KNFDGABE_00347 8.74e-299 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNFDGABE_00349 3.97e-97 - - - O - - - OsmC-like protein
KNFDGABE_00350 1.54e-224 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNFDGABE_00351 1.44e-275 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KNFDGABE_00352 8.68e-44 - - - - - - - -
KNFDGABE_00353 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
KNFDGABE_00355 4.56e-52 - - - K - - - PFAM GCN5-related N-acetyltransferase
KNFDGABE_00356 4.3e-50 - - - K - - - PFAM GCN5-related N-acetyltransferase
KNFDGABE_00357 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNFDGABE_00358 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KNFDGABE_00359 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KNFDGABE_00360 2.2e-223 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KNFDGABE_00361 6.46e-266 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KNFDGABE_00362 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KNFDGABE_00363 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KNFDGABE_00364 1.76e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KNFDGABE_00365 3.43e-300 - - - L - - - Transposase
KNFDGABE_00366 3.8e-92 - - - - - - - -
KNFDGABE_00367 1.24e-112 - - - T - - - Region found in RelA / SpoT proteins
KNFDGABE_00368 1.01e-149 dltr - - K - - - response regulator
KNFDGABE_00369 5.36e-288 sptS - - T - - - Histidine kinase
KNFDGABE_00370 4.71e-264 - - - P - - - Voltage gated chloride channel
KNFDGABE_00371 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KNFDGABE_00372 4.32e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
KNFDGABE_00373 4.24e-214 - - - C - - - Aldo keto reductase
KNFDGABE_00374 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
KNFDGABE_00375 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
KNFDGABE_00376 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KNFDGABE_00377 1.46e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNFDGABE_00378 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNFDGABE_00379 5.13e-121 - - - - - - - -
KNFDGABE_00380 4.65e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNFDGABE_00382 6.88e-144 - - - K - - - Transcriptional regulator, TetR family
KNFDGABE_00383 2.35e-92 - - - - - - - -
KNFDGABE_00384 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KNFDGABE_00385 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
KNFDGABE_00386 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
KNFDGABE_00387 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KNFDGABE_00388 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
KNFDGABE_00389 1.91e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KNFDGABE_00390 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KNFDGABE_00391 8.52e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
KNFDGABE_00392 1.99e-199 yvgN - - S - - - Aldo keto reductase
KNFDGABE_00393 2.71e-258 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
KNFDGABE_00394 1.95e-109 uspA - - T - - - universal stress protein
KNFDGABE_00395 5.13e-61 - - - - - - - -
KNFDGABE_00396 4.83e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KNFDGABE_00397 4.1e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KNFDGABE_00398 9.79e-29 - - - - - - - -
KNFDGABE_00399 2e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
KNFDGABE_00400 4.16e-180 - - - S - - - Membrane
KNFDGABE_00401 9.4e-178 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KNFDGABE_00402 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KNFDGABE_00403 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KNFDGABE_00404 5.97e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KNFDGABE_00405 2.25e-85 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KNFDGABE_00406 1.2e-76 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
KNFDGABE_00407 5.97e-120 - - - L - - - Transposase
KNFDGABE_00408 2.57e-125 - - - L - - - Transposase
KNFDGABE_00409 3.89e-203 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
KNFDGABE_00410 0.0 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
KNFDGABE_00412 1.5e-18 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
KNFDGABE_00413 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KNFDGABE_00414 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KNFDGABE_00415 3.94e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KNFDGABE_00416 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNFDGABE_00417 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KNFDGABE_00418 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
KNFDGABE_00419 9.42e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
KNFDGABE_00420 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KNFDGABE_00421 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KNFDGABE_00422 1.09e-295 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KNFDGABE_00423 2.9e-310 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KNFDGABE_00424 3.6e-158 radC - - L ko:K03630 - ko00000 DNA repair protein
KNFDGABE_00425 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
KNFDGABE_00426 3.67e-193 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KNFDGABE_00427 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
KNFDGABE_00428 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KNFDGABE_00429 3.42e-150 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00430 4.04e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KNFDGABE_00431 2.04e-292 ymfF - - S - - - Peptidase M16 inactive domain protein
KNFDGABE_00432 1.92e-316 ymfH - - S - - - Peptidase M16
KNFDGABE_00433 1.97e-195 - - - S - - - Helix-turn-helix domain
KNFDGABE_00434 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNFDGABE_00435 4.11e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KNFDGABE_00436 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNFDGABE_00437 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KNFDGABE_00438 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KNFDGABE_00439 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNFDGABE_00440 5.28e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KNFDGABE_00441 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KNFDGABE_00442 5.3e-243 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KNFDGABE_00443 2.91e-59 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KNFDGABE_00444 6.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
KNFDGABE_00445 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KNFDGABE_00446 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNFDGABE_00447 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
KNFDGABE_00448 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KNFDGABE_00449 7.57e-63 yrzB - - S - - - Belongs to the UPF0473 family
KNFDGABE_00450 7.15e-122 cvpA - - S - - - Colicin V production protein
KNFDGABE_00451 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KNFDGABE_00452 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KNFDGABE_00453 1.74e-125 yslB - - S - - - Protein of unknown function (DUF2507)
KNFDGABE_00454 7.39e-184 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KNFDGABE_00455 9.55e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNFDGABE_00456 7.84e-119 - - - S ko:K07095 - ko00000 Phosphoesterase
KNFDGABE_00457 3.48e-98 ykuL - - S - - - (CBS) domain
KNFDGABE_00458 1.1e-195 - - - S - - - haloacid dehalogenase-like hydrolase
KNFDGABE_00459 6.5e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KNFDGABE_00460 1.26e-70 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KNFDGABE_00461 1.84e-75 - - - - - - - -
KNFDGABE_00462 5.75e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KNFDGABE_00463 4.66e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KNFDGABE_00464 8.11e-179 - - - - - - - -
KNFDGABE_00465 7.07e-168 yebC - - K - - - Transcriptional regulatory protein
KNFDGABE_00466 1.45e-235 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
KNFDGABE_00467 1.34e-236 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KNFDGABE_00468 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
KNFDGABE_00469 1.43e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
KNFDGABE_00470 2.38e-56 - - - - - - - -
KNFDGABE_00471 1.88e-91 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
KNFDGABE_00473 5.09e-186 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
KNFDGABE_00474 5.31e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNFDGABE_00475 1.21e-143 - - - S - - - Calcineurin-like phosphoesterase
KNFDGABE_00476 2.66e-120 yutD - - S - - - Protein of unknown function (DUF1027)
KNFDGABE_00477 4.08e-171 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KNFDGABE_00478 4.18e-131 - - - S - - - Protein of unknown function (DUF1461)
KNFDGABE_00479 1.83e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
KNFDGABE_00480 9.95e-168 - - - L ko:K07484 - ko00000 Transposase IS66 family
KNFDGABE_00481 2.89e-124 - - - K - - - Acetyltransferase (GNAT) domain
KNFDGABE_00482 1.52e-301 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
KNFDGABE_00483 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KNFDGABE_00484 7.95e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNFDGABE_00485 2.23e-204 - - - O - - - Uncharacterized protein family (UPF0051)
KNFDGABE_00486 2.03e-134 - - - M - - - LysM domain protein
KNFDGABE_00487 0.0 - - - EP - - - Psort location Cytoplasmic, score
KNFDGABE_00488 1.23e-141 - - - M - - - LysM domain protein
KNFDGABE_00489 4.89e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KNFDGABE_00490 2.81e-298 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KNFDGABE_00491 3.79e-308 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KNFDGABE_00492 1.23e-194 yeaE - - S - - - Aldo keto
KNFDGABE_00493 3.13e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KNFDGABE_00494 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
KNFDGABE_00495 1.54e-101 - - - S - - - Psort location Cytoplasmic, score
KNFDGABE_00496 2.91e-110 - - - S - - - Short repeat of unknown function (DUF308)
KNFDGABE_00497 7.03e-33 - - - - - - - -
KNFDGABE_00498 5.76e-134 - - - V - - - VanZ like family
KNFDGABE_00499 5.75e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KNFDGABE_00500 1.46e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KNFDGABE_00501 0.0 - - - EGP - - - Major Facilitator
KNFDGABE_00502 5.22e-120 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KNFDGABE_00503 2.71e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNFDGABE_00504 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KNFDGABE_00505 1.02e-55 - - - - - - - -
KNFDGABE_00506 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KNFDGABE_00507 1.18e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KNFDGABE_00508 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
KNFDGABE_00509 1.79e-111 - - - T - - - Belongs to the universal stress protein A family
KNFDGABE_00510 9.29e-233 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KNFDGABE_00511 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
KNFDGABE_00512 6.22e-146 - - - - - - - -
KNFDGABE_00513 2.82e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
KNFDGABE_00514 4.68e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNFDGABE_00515 1.78e-42 - - - - - - - -
KNFDGABE_00516 3.64e-150 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
KNFDGABE_00517 2.63e-58 - - - - - - - -
KNFDGABE_00519 1.54e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KNFDGABE_00520 6.09e-86 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KNFDGABE_00521 1.27e-90 - - - - - - - -
KNFDGABE_00522 3.95e-71 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KNFDGABE_00523 1.46e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KNFDGABE_00524 4.77e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
KNFDGABE_00525 9.52e-284 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KNFDGABE_00526 3.47e-135 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
KNFDGABE_00527 4.76e-268 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
KNFDGABE_00528 1.88e-60 - - - - - - - -
KNFDGABE_00529 1.49e-54 - - - - - - - -
KNFDGABE_00531 2.24e-212 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KNFDGABE_00532 1.45e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KNFDGABE_00533 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KNFDGABE_00534 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KNFDGABE_00535 3.9e-79 yheA - - S - - - Belongs to the UPF0342 family
KNFDGABE_00536 3.27e-276 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
KNFDGABE_00537 0.0 yhaN - - L - - - AAA domain
KNFDGABE_00538 4.08e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KNFDGABE_00540 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
KNFDGABE_00541 1.9e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00542 2.82e-280 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KNFDGABE_00543 3.07e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KNFDGABE_00544 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KNFDGABE_00545 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KNFDGABE_00546 1.1e-233 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KNFDGABE_00547 4.92e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KNFDGABE_00548 2.27e-75 - - - S - - - Small secreted protein
KNFDGABE_00549 2.95e-75 ytpP - - CO - - - Thioredoxin
KNFDGABE_00550 3.43e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNFDGABE_00551 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KNFDGABE_00552 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KNFDGABE_00553 5.87e-155 - - - S - - - Protein of unknown function (DUF1275)
KNFDGABE_00554 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNFDGABE_00555 7.53e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KNFDGABE_00556 3.57e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNFDGABE_00557 1.63e-104 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNFDGABE_00558 1.82e-296 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
KNFDGABE_00559 6.05e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KNFDGABE_00560 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KNFDGABE_00561 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KNFDGABE_00562 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNFDGABE_00563 7.78e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
KNFDGABE_00564 9.01e-278 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
KNFDGABE_00565 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
KNFDGABE_00566 1.4e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNFDGABE_00567 1.03e-145 yqeK - - H - - - Hydrolase, HD family
KNFDGABE_00568 1.56e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KNFDGABE_00569 1.83e-178 yqeM - - Q - - - Methyltransferase
KNFDGABE_00570 1.48e-268 ylbM - - S - - - Belongs to the UPF0348 family
KNFDGABE_00571 5.84e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KNFDGABE_00572 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KNFDGABE_00573 7.04e-288 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
KNFDGABE_00574 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
KNFDGABE_00575 1.72e-315 - - - E ko:K03294 - ko00000 amino acid
KNFDGABE_00576 5.69e-234 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNFDGABE_00578 7.41e-38 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KNFDGABE_00580 5.57e-269 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
KNFDGABE_00581 2.23e-54 - - - S - - - Cytochrome B5
KNFDGABE_00582 8.47e-08 - - - S - - - Cytochrome B5
KNFDGABE_00583 2.3e-52 - - - S - - - Cytochrome B5
KNFDGABE_00584 7.07e-97 - - - S ko:K02348 - ko00000 Gnat family
KNFDGABE_00585 1.11e-156 - - - GM - - - NmrA-like family
KNFDGABE_00586 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
KNFDGABE_00587 3.33e-140 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
KNFDGABE_00588 2.17e-107 - - - K - - - Transcriptional regulator, HxlR family
KNFDGABE_00589 3.24e-291 - - - - - - - -
KNFDGABE_00590 1.53e-268 - - - EGP - - - Major Facilitator Superfamily
KNFDGABE_00591 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KNFDGABE_00592 8.37e-145 - - - GM - - - NAD dependent epimerase dehydratase family protein
KNFDGABE_00593 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KNFDGABE_00594 1.78e-61 ywnA - - K - - - Transcriptional regulator
KNFDGABE_00595 1.31e-121 - - - S - - - ECF transporter, substrate-specific component
KNFDGABE_00596 2.89e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KNFDGABE_00597 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KNFDGABE_00599 8.44e-168 - - - F - - - glutamine amidotransferase
KNFDGABE_00600 7.08e-85 - - - - - - - -
KNFDGABE_00601 7.12e-142 - - - GM - - - NAD(P)H-binding
KNFDGABE_00602 7.3e-250 - - - S - - - membrane
KNFDGABE_00603 2.27e-134 - - - K - - - Transcriptional regulator C-terminal region
KNFDGABE_00604 4.29e-201 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KNFDGABE_00605 1.65e-187 - - - K - - - Transcriptional regulator
KNFDGABE_00606 5.69e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
KNFDGABE_00607 3.4e-213 ypuA - - S - - - Protein of unknown function (DUF1002)
KNFDGABE_00608 1.94e-290 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
KNFDGABE_00609 2.28e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KNFDGABE_00610 1.2e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
KNFDGABE_00611 6.91e-168 - - - S - - - Alpha beta hydrolase
KNFDGABE_00612 3.02e-113 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KNFDGABE_00613 7.25e-82 lysR - - K - - - Transcriptional regulator
KNFDGABE_00614 5.18e-109 - - - C - - - Flavodoxin
KNFDGABE_00615 9.59e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
KNFDGABE_00616 9.45e-210 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
KNFDGABE_00617 5.81e-99 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KNFDGABE_00618 5.94e-107 - - - K - - - Bacterial regulatory proteins, tetR family
KNFDGABE_00619 2e-73 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
KNFDGABE_00620 7.67e-142 - - - M - - - Protein of unknown function (DUF3737)
KNFDGABE_00621 2.82e-282 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KNFDGABE_00622 3.42e-13 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
KNFDGABE_00623 2.92e-139 - - - P - - - nitric oxide dioxygenase activity
KNFDGABE_00624 4.05e-133 - - - S - - - Peptidase propeptide and YPEB domain
KNFDGABE_00625 7.19e-298 - - - T - - - GHKL domain
KNFDGABE_00626 3.39e-155 - - - T - - - Transcriptional regulatory protein, C terminal
KNFDGABE_00627 2.71e-207 - - - S ko:K07088 - ko00000 Membrane transport protein
KNFDGABE_00628 8.29e-151 - - - H - - - RibD C-terminal domain
KNFDGABE_00633 5.17e-253 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KNFDGABE_00634 8.46e-154 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KNFDGABE_00635 4.96e-24 - - - - - - - -
KNFDGABE_00636 1.2e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
KNFDGABE_00637 7.91e-16 emrE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KNFDGABE_00638 1.72e-64 - - - EG - - - EamA-like transporter family
KNFDGABE_00639 4.76e-111 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
KNFDGABE_00640 9.89e-86 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNFDGABE_00641 6.03e-249 flp - - V - - - Beta-lactamase
KNFDGABE_00642 2.6e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KNFDGABE_00643 1.24e-161 - - - S ko:K07507 - ko00000,ko02000 MgtC family
KNFDGABE_00644 1.02e-20 - - - S - - - GyrI-like small molecule binding domain
KNFDGABE_00645 9.58e-21 - - - M - - - LPXTG-motif cell wall anchor domain protein
KNFDGABE_00646 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNFDGABE_00647 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_00648 3.28e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00649 6.17e-286 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KNFDGABE_00650 1.69e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
KNFDGABE_00651 3.5e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
KNFDGABE_00652 2.96e-208 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
KNFDGABE_00653 1.27e-162 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KNFDGABE_00654 5.06e-198 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KNFDGABE_00655 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
KNFDGABE_00656 1.32e-195 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KNFDGABE_00657 1.41e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
KNFDGABE_00658 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KNFDGABE_00659 7.35e-174 - - - S - - - Protein of unknown function (DUF1129)
KNFDGABE_00660 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KNFDGABE_00661 6.87e-300 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KNFDGABE_00662 9.54e-302 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
KNFDGABE_00663 2.69e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KNFDGABE_00664 2.03e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
KNFDGABE_00665 8.49e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNFDGABE_00666 9.76e-161 vanR - - K - - - response regulator
KNFDGABE_00667 2.83e-260 hpk31 - - T - - - Histidine kinase
KNFDGABE_00668 9.98e-195 - - - E - - - AzlC protein
KNFDGABE_00669 4.05e-70 - - - S - - - branched-chain amino acid
KNFDGABE_00670 4.81e-178 - - - K - - - LysR substrate binding domain
KNFDGABE_00671 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KNFDGABE_00672 8.66e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNFDGABE_00673 5.59e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KNFDGABE_00674 1.96e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KNFDGABE_00675 4.32e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNFDGABE_00676 1.35e-150 - - - S - - - Haloacid dehalogenase-like hydrolase
KNFDGABE_00677 3.73e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNFDGABE_00678 8.91e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KNFDGABE_00679 4.02e-219 ydbI - - K - - - AI-2E family transporter
KNFDGABE_00680 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KNFDGABE_00681 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KNFDGABE_00682 6.6e-168 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
KNFDGABE_00683 5.18e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KNFDGABE_00684 5.6e-272 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KNFDGABE_00685 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNFDGABE_00686 4.3e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KNFDGABE_00687 4.5e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNFDGABE_00688 1.15e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNFDGABE_00689 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNFDGABE_00690 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KNFDGABE_00691 5.37e-248 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KNFDGABE_00692 3.37e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KNFDGABE_00693 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KNFDGABE_00694 4.97e-311 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KNFDGABE_00695 3.05e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNFDGABE_00696 5.55e-227 - - - - - - - -
KNFDGABE_00697 1.21e-305 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNFDGABE_00698 0.0 - - - M - - - Rib/alpha-like repeat
KNFDGABE_00699 1.45e-262 - - - M - - - Rib/alpha-like repeat
KNFDGABE_00700 1.56e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KNFDGABE_00701 7.19e-266 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
KNFDGABE_00702 1.87e-132 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
KNFDGABE_00703 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNFDGABE_00704 1.05e-229 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
KNFDGABE_00705 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KNFDGABE_00706 3.6e-266 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KNFDGABE_00707 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KNFDGABE_00708 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KNFDGABE_00709 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KNFDGABE_00710 3.66e-159 int2 - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_00711 1.78e-120 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
KNFDGABE_00712 6.82e-99 - - - S - - - Bacteriophage holin family
KNFDGABE_00714 7.31e-05 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
KNFDGABE_00717 1.47e-60 - - - S - - - Calcineurin-like phosphoesterase
KNFDGABE_00718 0.000252 - - - - - - - -
KNFDGABE_00719 0.0 - - - M - - - Prophage endopeptidase tail
KNFDGABE_00720 1.57e-190 - - - S - - - phage tail
KNFDGABE_00721 1.27e-109 - - - D - - - Phage tail tape measure protein
KNFDGABE_00722 4.1e-74 - - - - - - - -
KNFDGABE_00723 4.1e-73 - - - S - - - Phage tail assembly chaperone protein, TAC
KNFDGABE_00724 1.65e-133 - - - S - - - Phage tail tube protein
KNFDGABE_00725 1.75e-27 - - - S - - - Protein of unknown function (DUF3168)
KNFDGABE_00726 5.94e-88 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KNFDGABE_00727 2.36e-53 - - - - - - - -
KNFDGABE_00728 1.53e-71 - - - S - - - Phage gp6-like head-tail connector protein
KNFDGABE_00729 1.15e-123 - - - - - - - -
KNFDGABE_00730 2.09e-47 - - - S - - - aminoacyl-tRNA ligase activity
KNFDGABE_00731 1.89e-44 - - - S - - - YjcQ protein
KNFDGABE_00733 1.52e-259 - - - S - - - Phage Mu protein F like protein
KNFDGABE_00734 2.62e-203 - - - S - - - Phage portal protein
KNFDGABE_00735 2.22e-178 - - - S - - - Terminase-like family
KNFDGABE_00736 2.53e-59 - - - L ko:K07474 - ko00000 Terminase small subunit
KNFDGABE_00737 2.67e-22 - - - S - - - Super-infection exclusion protein B
KNFDGABE_00738 5.1e-105 - - - S - - - Phage transcriptional regulator, ArpU family
KNFDGABE_00746 5.11e-28 - - - - - - - -
KNFDGABE_00747 2.89e-39 - - - L - - - Endodeoxyribonuclease RusA
KNFDGABE_00748 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
KNFDGABE_00749 0.0 - - - L - - - Helicase C-terminal domain protein
KNFDGABE_00750 7.94e-91 - - - - - - - -
KNFDGABE_00751 4.94e-152 - - - S - - - AAA domain
KNFDGABE_00752 1.24e-31 - - - S - - - Siphovirus Gp157
KNFDGABE_00754 4.37e-43 - - - - - - - -
KNFDGABE_00757 6.09e-51 - - - - - - - -
KNFDGABE_00758 1.48e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_00759 1.74e-83 - - - K - - - Peptidase S24-like
KNFDGABE_00762 5.55e-83 - - - V - - - Abi-like protein
KNFDGABE_00763 7.87e-184 int2 - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_00773 9.32e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KNFDGABE_00774 2.73e-204 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
KNFDGABE_00775 2.17e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KNFDGABE_00776 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KNFDGABE_00777 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
KNFDGABE_00778 9.81e-77 - - - - - - - -
KNFDGABE_00779 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KNFDGABE_00780 2.1e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KNFDGABE_00781 5.99e-74 ftsL - - D - - - Cell division protein FtsL
KNFDGABE_00782 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KNFDGABE_00783 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNFDGABE_00784 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNFDGABE_00785 9.81e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNFDGABE_00786 7.99e-191 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KNFDGABE_00787 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KNFDGABE_00788 3.1e-287 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNFDGABE_00789 1.57e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KNFDGABE_00790 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
KNFDGABE_00791 2.61e-190 ylmH - - S - - - S4 domain protein
KNFDGABE_00792 6.11e-108 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
KNFDGABE_00793 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNFDGABE_00794 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KNFDGABE_00795 8.32e-128 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KNFDGABE_00796 7.05e-23 - - - - - - - -
KNFDGABE_00797 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNFDGABE_00798 1.05e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KNFDGABE_00799 2.27e-75 XK27_04120 - - S - - - Putative amino acid metabolism
KNFDGABE_00800 6.17e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KNFDGABE_00801 1.15e-158 pgm6 - - G - - - phosphoglycerate mutase
KNFDGABE_00802 3.82e-157 - - - S - - - repeat protein
KNFDGABE_00803 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KNFDGABE_00804 1.48e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNFDGABE_00806 2.05e-186 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KNFDGABE_00807 1.51e-126 - - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KNFDGABE_00808 7.69e-170 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00809 1.73e-161 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
KNFDGABE_00810 4.82e-194 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
KNFDGABE_00811 1.29e-231 - - - G - - - Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KNFDGABE_00812 6.92e-228 - - - L - - - Transposase
KNFDGABE_00813 2.04e-127 - - - L - - - Transposase
KNFDGABE_00814 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
KNFDGABE_00815 6.5e-71 - - - - - - - -
KNFDGABE_00816 2.91e-147 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KNFDGABE_00817 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00818 1.81e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KNFDGABE_00819 4.21e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
KNFDGABE_00820 1.1e-177 - - - IQ - - - KR domain
KNFDGABE_00821 7.76e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
KNFDGABE_00822 1.98e-232 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KNFDGABE_00823 7.09e-132 - - - S - - - Double zinc ribbon
KNFDGABE_00824 5.18e-235 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KNFDGABE_00826 6.47e-170 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KNFDGABE_00827 1.62e-17 - - - S - - - Domain of unknown function (DUF4767)
KNFDGABE_00831 1.27e-29 - - - S - - - Domain of unknown function (DUF4767)
KNFDGABE_00833 2.38e-189 - - - S - - - PD-(D/E)XK nuclease family transposase
KNFDGABE_00834 1.35e-33 - - - S - - - PD-(D/E)XK nuclease family transposase
KNFDGABE_00835 6e-58 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KNFDGABE_00836 3.86e-26 agrC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KNFDGABE_00838 2.97e-166 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNFDGABE_00839 1.5e-47 - - - - - - - -
KNFDGABE_00840 2.13e-120 - - - L - - - Integrase
KNFDGABE_00842 3.64e-39 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KNFDGABE_00843 1.5e-55 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
KNFDGABE_00850 4.08e-43 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
KNFDGABE_00851 2.47e-112 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
KNFDGABE_00854 2.06e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KNFDGABE_00855 1.61e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KNFDGABE_00856 8.43e-198 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNFDGABE_00857 2.24e-301 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KNFDGABE_00858 7.94e-42 - - - S - - - Protein of unknown function (DUF2929)
KNFDGABE_00859 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KNFDGABE_00860 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KNFDGABE_00861 2.27e-216 yitL - - S ko:K00243 - ko00000 S1 domain
KNFDGABE_00862 3.89e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
KNFDGABE_00863 7.13e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNFDGABE_00864 1.13e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNFDGABE_00865 1.29e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNFDGABE_00866 1.01e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KNFDGABE_00867 8.52e-130 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KNFDGABE_00868 5.82e-250 - - - S - - - Helix-turn-helix domain
KNFDGABE_00869 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KNFDGABE_00870 1.04e-69 - - - M - - - Lysin motif
KNFDGABE_00871 7.34e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KNFDGABE_00872 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KNFDGABE_00873 9.51e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KNFDGABE_00874 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNFDGABE_00875 9.5e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
KNFDGABE_00876 2.86e-286 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KNFDGABE_00877 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_00878 5.75e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNFDGABE_00879 1.88e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNFDGABE_00880 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
KNFDGABE_00881 1.1e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
KNFDGABE_00882 9.66e-221 - - - E - - - lipolytic protein G-D-S-L family
KNFDGABE_00883 2.01e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
KNFDGABE_00884 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
KNFDGABE_00885 2.08e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNFDGABE_00886 3.03e-182 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNFDGABE_00887 1.58e-206 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KNFDGABE_00888 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNFDGABE_00889 1e-214 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KNFDGABE_00890 2.22e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KNFDGABE_00891 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNFDGABE_00892 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNFDGABE_00893 8.38e-103 - - - F - - - NUDIX domain
KNFDGABE_00894 1.22e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KNFDGABE_00895 1.5e-88 - - - S - - - Belongs to the HesB IscA family
KNFDGABE_00896 3.19e-66 - - - - - - - -
KNFDGABE_00898 1.04e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KNFDGABE_00899 8.08e-83 asp1 - - S - - - Asp23 family, cell envelope-related function
KNFDGABE_00900 1.04e-33 - - - - - - - -
KNFDGABE_00901 5.41e-123 - - - - - - - -
KNFDGABE_00902 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KNFDGABE_00903 2.38e-233 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
KNFDGABE_00904 3.82e-295 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
KNFDGABE_00905 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KNFDGABE_00906 4.86e-124 - - - K - - - Acetyltransferase (GNAT) domain
KNFDGABE_00907 3.8e-63 - - - - - - - -
KNFDGABE_00908 1.81e-41 - - - - - - - -
KNFDGABE_00909 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
KNFDGABE_00910 1.26e-60 - - - - - - - -
KNFDGABE_00911 4.71e-97 - - - S - - - Protein of unknown function (DUF805)
KNFDGABE_00912 1.39e-127 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KNFDGABE_00913 0.0 - - - L - - - PLD-like domain
KNFDGABE_00915 5.01e-228 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
KNFDGABE_00916 6.85e-234 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNFDGABE_00917 7.64e-121 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KNFDGABE_00918 9.19e-287 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KNFDGABE_00919 7.5e-100 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KNFDGABE_00920 3.01e-145 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
KNFDGABE_00921 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KNFDGABE_00922 9.82e-262 - - - G - - - Transporter, major facilitator family protein
KNFDGABE_00923 1.13e-138 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
KNFDGABE_00924 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
KNFDGABE_00925 4.03e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KNFDGABE_00926 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KNFDGABE_00927 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
KNFDGABE_00928 1.65e-41 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
KNFDGABE_00929 4.46e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KNFDGABE_00930 7.05e-307 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
KNFDGABE_00931 1.29e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNFDGABE_00932 5.28e-105 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KNFDGABE_00933 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KNFDGABE_00934 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
KNFDGABE_00935 4.51e-204 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KNFDGABE_00936 1.38e-145 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
KNFDGABE_00937 2.38e-50 - - - S - - - Cytochrome B5
KNFDGABE_00938 1.11e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KNFDGABE_00939 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
KNFDGABE_00940 3.12e-191 - - - O - - - Band 7 protein
KNFDGABE_00941 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
KNFDGABE_00942 4.24e-162 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
KNFDGABE_00943 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
KNFDGABE_00944 3.6e-160 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
KNFDGABE_00945 1.68e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KNFDGABE_00946 2.46e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KNFDGABE_00947 2.61e-236 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
KNFDGABE_00948 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KNFDGABE_00949 3.35e-121 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
KNFDGABE_00950 1.8e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KNFDGABE_00951 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KNFDGABE_00952 1.71e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KNFDGABE_00953 1.04e-219 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
KNFDGABE_00954 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KNFDGABE_00955 1.57e-113 ypmB - - S - - - Protein conserved in bacteria
KNFDGABE_00956 3.24e-157 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
KNFDGABE_00957 2.42e-208 - - - EG - - - EamA-like transporter family
KNFDGABE_00958 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
KNFDGABE_00959 7.01e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KNFDGABE_00960 4.11e-131 ypsA - - S - - - Belongs to the UPF0398 family
KNFDGABE_00961 3.25e-72 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KNFDGABE_00962 1.01e-109 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
KNFDGABE_00963 2.07e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KNFDGABE_00964 1.16e-131 - - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_00965 1.66e-58 - - - - - - - -
KNFDGABE_00966 1.29e-56 - - - - - - - -
KNFDGABE_00967 1.24e-24 - - - - - - - -
KNFDGABE_00968 1.94e-91 - - - S - - - IrrE N-terminal-like domain
KNFDGABE_00969 1.6e-34 - - - K - - - Helix-turn-helix domain
KNFDGABE_00982 1.11e-05 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KNFDGABE_00985 6.59e-110 - - - S - - - Bacteriophage Mu Gam like protein
KNFDGABE_00986 2.38e-153 - - - S - - - AAA domain
KNFDGABE_00987 1.43e-110 - - - S - - - Protein of unknown function (DUF669)
KNFDGABE_00988 2.25e-82 - - - S - - - Putative HNHc nuclease
KNFDGABE_00989 1.71e-40 - - - L - - - Psort location Cytoplasmic, score
KNFDGABE_00990 2.52e-69 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
KNFDGABE_00994 5.19e-20 - - - - - - - -
KNFDGABE_00999 1.6e-42 - - - L - - - HNH endonuclease domain protein
KNFDGABE_01003 2.01e-28 - - - - - - - -
KNFDGABE_01005 8.8e-62 - - - S - - - Protein of unknown function (DUF1064)
KNFDGABE_01014 2.9e-24 - - - - - - - -
KNFDGABE_01015 4.5e-155 xtmA - - L ko:K07474 - ko00000 Terminase small subunit
KNFDGABE_01016 4.25e-274 - - - S - - - Terminase-like family
KNFDGABE_01017 1.71e-273 - - - S - - - Phage portal protein, SPP1 Gp6-like
KNFDGABE_01018 5.37e-192 - - - S - - - Phage Mu protein F like protein
KNFDGABE_01019 8.66e-81 - - - S - - - Domain of unknown function (DUF4355)
KNFDGABE_01020 1.22e-68 - - - - - - - -
KNFDGABE_01021 8.56e-215 - - - S - - - Phage major capsid protein E
KNFDGABE_01022 1.15e-46 - - - - - - - -
KNFDGABE_01023 3.27e-72 - - - - - - - -
KNFDGABE_01024 3.83e-103 - - - - - - - -
KNFDGABE_01025 1.02e-58 - - - - - - - -
KNFDGABE_01026 9.26e-94 - - - S - - - Phage tail tube protein, TTP
KNFDGABE_01027 8.06e-76 - - - - - - - -
KNFDGABE_01028 2.15e-42 - - - - - - - -
KNFDGABE_01029 0.0 - - - L - - - Phage tail tape measure protein TP901
KNFDGABE_01030 5.44e-70 - - - - - - - -
KNFDGABE_01031 0.0 - - - LM - - - gp58-like protein
KNFDGABE_01035 1.29e-235 - - - M - - - lysozyme activity
KNFDGABE_01036 1.88e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
KNFDGABE_01037 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
KNFDGABE_01038 5.12e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNFDGABE_01039 1.07e-56 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KNFDGABE_01040 1.54e-152 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KNFDGABE_01041 1.58e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
KNFDGABE_01042 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KNFDGABE_01043 0.0 FbpA - - K - - - Fibronectin-binding protein
KNFDGABE_01044 2.95e-207 - - - S - - - EDD domain protein, DegV family
KNFDGABE_01045 7.18e-126 - - - - - - - -
KNFDGABE_01046 7.48e-155 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KNFDGABE_01047 2.83e-200 gspA - - M - - - family 8
KNFDGABE_01048 4.91e-205 - - - S - - - Alpha beta hydrolase
KNFDGABE_01049 9.11e-123 - - - K - - - Acetyltransferase (GNAT) domain
KNFDGABE_01050 6.38e-106 - - - S - - - Cupin domain
KNFDGABE_01051 3.87e-97 - - - S - - - UPF0756 membrane protein
KNFDGABE_01052 3.38e-308 - - - U - - - Belongs to the major facilitator superfamily
KNFDGABE_01053 1.68e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
KNFDGABE_01054 1.84e-316 yhdP - - S - - - Transporter associated domain
KNFDGABE_01055 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
KNFDGABE_01056 3.51e-184 - - - S - - - DUF218 domain
KNFDGABE_01057 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNFDGABE_01058 3.06e-77 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNFDGABE_01059 3.5e-70 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNFDGABE_01060 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
KNFDGABE_01061 1.68e-157 - - - S - - - SNARE associated Golgi protein
KNFDGABE_01062 3.65e-291 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KNFDGABE_01063 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KNFDGABE_01065 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
KNFDGABE_01066 2.83e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
KNFDGABE_01067 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNFDGABE_01068 1.38e-54 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
KNFDGABE_01069 3.75e-93 - - - S - - - Protein of unknown function (DUF3290)
KNFDGABE_01070 2.82e-147 - - - S - - - Protein of unknown function (DUF421)
KNFDGABE_01071 7.91e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KNFDGABE_01072 5.02e-29 - - - - - - - -
KNFDGABE_01073 2.68e-115 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
KNFDGABE_01074 2.28e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KNFDGABE_01075 1.94e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
KNFDGABE_01077 6.27e-30 - - - M - - - Glycosyl hydrolases family 25
KNFDGABE_01078 1.75e-97 - - - L - - - PFAM Integrase catalytic region
KNFDGABE_01079 6.4e-26 - - - S - - - Phage derived protein Gp49-like (DUF891)
KNFDGABE_01080 3.09e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_01081 2.61e-11 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_01082 6.61e-205 - - - I - - - alpha/beta hydrolase fold
KNFDGABE_01083 1.69e-145 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KNFDGABE_01084 1.29e-72 - - - - - - - -
KNFDGABE_01093 1.66e-169 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KNFDGABE_01094 1.73e-173 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
KNFDGABE_01095 5.43e-180 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNFDGABE_01096 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
KNFDGABE_01097 1.1e-74 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KNFDGABE_01099 3.42e-258 xerS - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01100 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
KNFDGABE_01101 3.44e-202 rssA - - S - - - Phospholipase, patatin family
KNFDGABE_01102 9.45e-152 - - - L - - - Integrase
KNFDGABE_01103 8.94e-195 - - - EG - - - EamA-like transporter family
KNFDGABE_01104 2.71e-167 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
KNFDGABE_01105 1.72e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
KNFDGABE_01106 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KNFDGABE_01107 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KNFDGABE_01108 3.18e-237 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
KNFDGABE_01109 1.72e-109 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KNFDGABE_01110 1.17e-286 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
KNFDGABE_01111 3.2e-97 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KNFDGABE_01112 2.53e-121 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KNFDGABE_01113 1.56e-60 - - - - - - - -
KNFDGABE_01114 3.57e-238 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
KNFDGABE_01115 4.31e-149 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
KNFDGABE_01116 1.26e-25 - - - - - - - -
KNFDGABE_01117 2.79e-227 - - - - - - - -
KNFDGABE_01118 1.42e-180 - - - H - - - geranyltranstransferase activity
KNFDGABE_01119 2.5e-277 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
KNFDGABE_01120 5.33e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
KNFDGABE_01121 3.65e-81 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
KNFDGABE_01122 9.93e-99 - - - S - - - Flavodoxin
KNFDGABE_01123 1.02e-164 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNFDGABE_01124 1.42e-172 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KNFDGABE_01125 1.48e-226 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KNFDGABE_01126 3.93e-221 - - - - - - - -
KNFDGABE_01127 9.01e-95 - - - - - - - -
KNFDGABE_01128 1.7e-157 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
KNFDGABE_01129 0.0 - - - S - - - SEC-C Motif Domain Protein
KNFDGABE_01130 3.54e-67 - - - - - - - -
KNFDGABE_01131 2.54e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KNFDGABE_01132 3.92e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KNFDGABE_01133 1.29e-149 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KNFDGABE_01134 1.24e-295 - - - P - - - Chloride transporter, ClC family
KNFDGABE_01135 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
KNFDGABE_01136 5.89e-145 - - - I - - - Acid phosphatase homologues
KNFDGABE_01138 2.41e-125 - - - L - - - Transposase
KNFDGABE_01139 1.29e-107 isp - - L - - - Transposase
KNFDGABE_01140 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KNFDGABE_01141 4.08e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KNFDGABE_01142 5.67e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KNFDGABE_01143 3.69e-259 coiA - - S ko:K06198 - ko00000 Competence protein
KNFDGABE_01144 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNFDGABE_01145 1.4e-147 yjbH - - Q - - - Thioredoxin
KNFDGABE_01146 1.29e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KNFDGABE_01147 1.25e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KNFDGABE_01148 5.6e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KNFDGABE_01149 3.03e-30 - - - S - - - DNA binding domain, excisionase family
KNFDGABE_01151 7.05e-149 - - - - - - - -
KNFDGABE_01154 3.96e-100 tnpR1 - - L - - - Resolvase, N terminal domain
KNFDGABE_01158 2.03e-248 int7 - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01159 1.27e-110 - - - - - - - -
KNFDGABE_01179 3.88e-202 - - - L ko:K07497 - ko00000 hmm pf00665
KNFDGABE_01180 2.79e-164 - - - L - - - Helix-turn-helix domain
KNFDGABE_01181 1.51e-253 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
KNFDGABE_01183 0.0 - - - - - - - -
KNFDGABE_01184 3.11e-212 - - - - - - - -
KNFDGABE_01185 0.0 - - - - - - - -
KNFDGABE_01186 1.67e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KNFDGABE_01187 1.95e-133 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KNFDGABE_01188 5.24e-92 - - - - - - - -
KNFDGABE_01189 1.66e-43 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNFDGABE_01190 1.08e-23 - - - L - - - nuclease
KNFDGABE_01191 2.11e-119 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNFDGABE_01192 7.01e-38 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNFDGABE_01193 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
KNFDGABE_01194 4.36e-263 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KNFDGABE_01195 2.52e-224 - - - M - - - Glycosyl hydrolases family 25
KNFDGABE_01196 1.68e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
KNFDGABE_01197 0.0 snf - - KL - - - domain protein
KNFDGABE_01199 2.87e-180 - - - S - - - Protein of unknown function (DUF3800)
KNFDGABE_01202 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KNFDGABE_01203 5.36e-219 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KNFDGABE_01205 1.5e-23 - - - S - - - Protein of unknown function (DUF4065)
KNFDGABE_01206 1.56e-35 - - - S - - - Protein of unknown function (DUF4065)
KNFDGABE_01207 3.77e-34 - - - S - - - Region found in RelA / SpoT proteins
KNFDGABE_01208 9.92e-166 - 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NAD(P)H-binding
KNFDGABE_01209 2.11e-06 - - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
KNFDGABE_01210 5.49e-28 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KNFDGABE_01211 9.76e-27 - - - - - - - -
KNFDGABE_01214 4.93e-66 - - - V - - - Type I restriction modification DNA specificity domain
KNFDGABE_01215 8.38e-289 - - - V - - - N-6 DNA Methylase
KNFDGABE_01217 5.67e-214 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD/REP helicase N-terminal domain
KNFDGABE_01218 6.66e-266 - - - L - - - AAA ATPase domain
KNFDGABE_01219 7.72e-11 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KNFDGABE_01220 7.38e-143 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KNFDGABE_01221 3.04e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KNFDGABE_01223 3.05e-110 - - - M - - - Glycosyltransferase, group 1 family protein
KNFDGABE_01224 1.48e-123 - - - M - - - Glycosyltransferase
KNFDGABE_01225 4.12e-41 - - - S - - - Glycosyltransferase family 28 C-terminal domain
KNFDGABE_01226 8.82e-45 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
KNFDGABE_01227 1.03e-37 - - - M - - - Glycosyltransferase like family 2
KNFDGABE_01228 3.43e-148 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KNFDGABE_01229 1.28e-78 cps3F - - - - - - -
KNFDGABE_01230 8.28e-93 - - - S - - - Bacterial transferase hexapeptide (six repeats)
KNFDGABE_01231 2.36e-97 - - - M - - - Glycosyltransferase like family 2
KNFDGABE_01232 1.65e-133 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
KNFDGABE_01233 1.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
KNFDGABE_01234 3.93e-191 epsB - - M - - - biosynthesis protein
KNFDGABE_01235 9.53e-220 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KNFDGABE_01236 1.8e-86 - - - K - - - Transcriptional regulator, HxlR family
KNFDGABE_01237 3.51e-164 - - - - - - - -
KNFDGABE_01238 6.76e-131 - - - K - - - DNA-templated transcription, initiation
KNFDGABE_01239 2.38e-50 - - - - - - - -
KNFDGABE_01240 3.21e-115 - - - - - - - -
KNFDGABE_01241 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNFDGABE_01242 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KNFDGABE_01243 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
KNFDGABE_01244 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNFDGABE_01250 0.0 - - - M - - - family 8
KNFDGABE_01252 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KNFDGABE_01253 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KNFDGABE_01254 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KNFDGABE_01255 2.45e-212 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
KNFDGABE_01256 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
KNFDGABE_01257 0.0 - - - M - - - transferase activity, transferring glycosyl groups
KNFDGABE_01258 1.03e-264 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
KNFDGABE_01259 2.09e-244 - - - M - - - transferase activity, transferring glycosyl groups
KNFDGABE_01260 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KNFDGABE_01261 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
KNFDGABE_01262 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
KNFDGABE_01263 5.58e-192 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KNFDGABE_01264 1.1e-157 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
KNFDGABE_01266 3.52e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNFDGABE_01267 4.08e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
KNFDGABE_01268 4.44e-292 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KNFDGABE_01269 5.88e-164 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KNFDGABE_01270 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
KNFDGABE_01271 3.97e-229 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KNFDGABE_01272 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
KNFDGABE_01273 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KNFDGABE_01274 1.64e-239 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KNFDGABE_01275 6.95e-59 - - - S - - - CRISPR-associated protein (Cas_Csn2)
KNFDGABE_01276 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNFDGABE_01277 7.63e-141 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNFDGABE_01278 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNFDGABE_01279 1.55e-109 - - - - - - - -
KNFDGABE_01280 5.11e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KNFDGABE_01281 1.75e-69 - - - S - - - Mazg nucleotide pyrophosphohydrolase
KNFDGABE_01282 4.45e-47 - - - - - - - -
KNFDGABE_01285 9.73e-54 - - - - - - - -
KNFDGABE_01288 1.21e-60 - - - - - - - -
KNFDGABE_01289 2.12e-217 - - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01290 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KNFDGABE_01291 0.0 - - - E ko:K03294 - ko00000 amino acid
KNFDGABE_01292 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KNFDGABE_01293 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNFDGABE_01294 2.17e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KNFDGABE_01295 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KNFDGABE_01296 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KNFDGABE_01297 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KNFDGABE_01298 5.34e-258 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KNFDGABE_01299 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KNFDGABE_01300 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KNFDGABE_01301 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNFDGABE_01302 4.72e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KNFDGABE_01303 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNFDGABE_01304 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
KNFDGABE_01305 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
KNFDGABE_01306 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KNFDGABE_01307 2.72e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KNFDGABE_01308 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KNFDGABE_01309 8.48e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KNFDGABE_01310 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KNFDGABE_01311 2.57e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KNFDGABE_01312 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNFDGABE_01313 4.27e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNFDGABE_01314 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNFDGABE_01315 5.41e-274 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNFDGABE_01316 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KNFDGABE_01317 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KNFDGABE_01318 7.12e-69 - - - - - - - -
KNFDGABE_01319 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KNFDGABE_01320 7.54e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KNFDGABE_01321 2.81e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KNFDGABE_01322 7.46e-200 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KNFDGABE_01323 2.83e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNFDGABE_01324 9.28e-279 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNFDGABE_01325 1.32e-191 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNFDGABE_01326 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNFDGABE_01327 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
KNFDGABE_01328 3.21e-143 - - - J - - - 2'-5' RNA ligase superfamily
KNFDGABE_01329 8.69e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KNFDGABE_01330 3.69e-168 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KNFDGABE_01331 1.78e-120 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
KNFDGABE_01332 2.33e-37 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
KNFDGABE_01333 2.14e-52 - - - - - - - -
KNFDGABE_01336 3.13e-67 - - - G - - - cellulose 1,4-beta-cellobiosidase activity
KNFDGABE_01337 7.97e-31 - - - - - - - -
KNFDGABE_01338 6.31e-148 - - - S - - - Baseplate J-like protein
KNFDGABE_01340 2.23e-37 - - - - - - - -
KNFDGABE_01341 1.83e-115 - - - - - - - -
KNFDGABE_01342 5.17e-46 - - - - - - - -
KNFDGABE_01343 1.06e-67 - - - M - - - LysM domain
KNFDGABE_01347 1.68e-48 - - - - - - - -
KNFDGABE_01348 1.67e-130 - - - S - - - Protein of unknown function (DUF3383)
KNFDGABE_01351 1.35e-64 - - - - - - - -
KNFDGABE_01352 9.17e-40 - - - - - - - -
KNFDGABE_01353 1.65e-25 - - - - - - - -
KNFDGABE_01354 1.16e-123 - - - - - - - -
KNFDGABE_01355 5.86e-47 - - - S - - - Domain of unknown function (DUF4355)
KNFDGABE_01356 6.93e-50 - - - S - - - YjcQ protein
KNFDGABE_01358 2.6e-112 - - - - - - - -
KNFDGABE_01359 1.82e-227 - - - S - - - Phage portal protein, SPP1 Gp6-like
KNFDGABE_01360 1.28e-239 - - - S - - - Terminase-like family
KNFDGABE_01361 7.11e-101 xtmA - - L ko:K07474 - ko00000 Terminase small subunit
KNFDGABE_01362 1.14e-26 - - - - - - - -
KNFDGABE_01367 7.39e-30 rusA - - L - - - Endodeoxyribonuclease RusA
KNFDGABE_01368 2.51e-106 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
KNFDGABE_01371 2.45e-12 - - - - - - - -
KNFDGABE_01372 3.91e-47 - - - S - - - ORF6C domain
KNFDGABE_01375 3.83e-68 - - - - - - - -
KNFDGABE_01376 4.83e-73 - - - L - - - Psort location Cytoplasmic, score
KNFDGABE_01377 3.2e-69 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
KNFDGABE_01378 1.69e-101 recT - - L ko:K07455 - ko00000,ko03400 RecT family
KNFDGABE_01382 4.53e-41 - - - - - - - -
KNFDGABE_01385 8.65e-73 - - - S - - - DNA binding
KNFDGABE_01386 3.41e-28 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
KNFDGABE_01387 6.11e-45 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_01388 1.56e-50 - - - E - - - Zn peptidase
KNFDGABE_01389 5.25e-25 - - - - - - - -
KNFDGABE_01390 3.48e-60 - - - - - - - -
KNFDGABE_01391 8.19e-267 - - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01392 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KNFDGABE_01393 4.18e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
KNFDGABE_01394 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KNFDGABE_01395 1.99e-146 - - - K - - - Transcriptional regulator
KNFDGABE_01398 8.5e-116 - - - S - - - Protein conserved in bacteria
KNFDGABE_01399 3.68e-233 - - - - - - - -
KNFDGABE_01400 1.39e-202 - - - - - - - -
KNFDGABE_01401 1.27e-66 yitW - - S - - - Iron-sulfur cluster assembly protein
KNFDGABE_01402 1.64e-130 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNFDGABE_01403 4.16e-198 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KNFDGABE_01404 1.28e-18 - - - - - - - -
KNFDGABE_01405 3.85e-279 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KNFDGABE_01406 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNFDGABE_01407 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KNFDGABE_01408 7.35e-220 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNFDGABE_01409 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
KNFDGABE_01410 7.66e-88 yqhL - - P - - - Rhodanese-like protein
KNFDGABE_01411 8.4e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KNFDGABE_01412 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
KNFDGABE_01413 2.99e-141 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
KNFDGABE_01414 1.38e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNFDGABE_01415 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KNFDGABE_01416 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KNFDGABE_01417 0.0 - - - S - - - membrane
KNFDGABE_01418 5.87e-86 yneR - - S - - - Belongs to the HesB IscA family
KNFDGABE_01419 3.52e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNFDGABE_01420 4.85e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KNFDGABE_01421 3.29e-146 - - - M - - - PFAM NLP P60 protein
KNFDGABE_01422 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNFDGABE_01423 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNFDGABE_01424 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
KNFDGABE_01425 4.38e-118 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KNFDGABE_01426 6.64e-187 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNFDGABE_01427 6.76e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KNFDGABE_01428 5.52e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNFDGABE_01429 1.52e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KNFDGABE_01430 1.61e-292 - - - V - - - MatE
KNFDGABE_01431 0.0 potE - - E - - - Amino Acid
KNFDGABE_01432 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNFDGABE_01433 5.62e-155 csrR - - K - - - response regulator
KNFDGABE_01436 2.01e-86 - - - L ko:K07484 - ko00000 Transposase IS66 family
KNFDGABE_01437 1.89e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_01438 5.19e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KNFDGABE_01439 8.55e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
KNFDGABE_01440 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KNFDGABE_01441 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
KNFDGABE_01442 1.05e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
KNFDGABE_01443 1e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNFDGABE_01444 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
KNFDGABE_01445 7.36e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KNFDGABE_01446 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNFDGABE_01447 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNFDGABE_01448 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNFDGABE_01449 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNFDGABE_01450 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KNFDGABE_01451 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNFDGABE_01452 1.55e-160 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KNFDGABE_01453 8.02e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
KNFDGABE_01454 8.15e-167 yibF - - S - - - overlaps another CDS with the same product name
KNFDGABE_01455 3.88e-245 yibE - - S - - - overlaps another CDS with the same product name
KNFDGABE_01456 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNFDGABE_01457 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNFDGABE_01458 7.71e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNFDGABE_01459 3.12e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KNFDGABE_01460 2.35e-211 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KNFDGABE_01461 4.07e-247 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNFDGABE_01462 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KNFDGABE_01463 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
KNFDGABE_01464 1.4e-172 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
KNFDGABE_01466 6.87e-298 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
KNFDGABE_01467 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KNFDGABE_01468 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KNFDGABE_01469 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
KNFDGABE_01470 1.29e-236 ampC - - V - - - Beta-lactamase
KNFDGABE_01471 2.76e-80 - - - - - - - -
KNFDGABE_01472 0.0 - - - M - - - domain protein
KNFDGABE_01473 2.46e-127 - - - - - - - -
KNFDGABE_01474 2.15e-170 int2 - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01475 2.41e-25 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KNFDGABE_01476 1.85e-24 - - - S - - - Helix-turn-helix domain
KNFDGABE_01477 3.79e-40 - - - - - - - -
KNFDGABE_01478 7.33e-57 - - - K - - - COG3617 Prophage antirepressor
KNFDGABE_01479 7.68e-07 - - - S - - - Helix-turn-helix domain
KNFDGABE_01485 2.23e-13 - - - L - - - DnaD domain protein
KNFDGABE_01487 2.98e-90 - - - - - - - -
KNFDGABE_01492 1.63e-50 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
KNFDGABE_01493 1.28e-75 - - - - - - - -
KNFDGABE_01495 5.22e-112 - - - - - - - -
KNFDGABE_01496 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KNFDGABE_01497 1.27e-64 - - - S - - - Cupredoxin-like domain
KNFDGABE_01498 5.13e-70 - - - S - - - Cupredoxin-like domain
KNFDGABE_01499 8.55e-135 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KNFDGABE_01500 7.8e-207 - - - EG - - - EamA-like transporter family
KNFDGABE_01501 1.37e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
KNFDGABE_01502 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KNFDGABE_01503 2.15e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
KNFDGABE_01504 5.02e-36 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
KNFDGABE_01506 2.69e-36 - - - - - - - -
KNFDGABE_01507 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KNFDGABE_01508 1.65e-151 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KNFDGABE_01509 9.07e-199 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KNFDGABE_01510 0.0 yclK - - T - - - Histidine kinase
KNFDGABE_01511 2.81e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
KNFDGABE_01513 5.74e-107 lytE - - M - - - Lysin motif
KNFDGABE_01514 5.46e-191 - - - S - - - Cof-like hydrolase
KNFDGABE_01515 3.45e-100 - - - K - - - Transcriptional regulator
KNFDGABE_01516 0.0 oatA - - I - - - Acyltransferase
KNFDGABE_01517 1.01e-67 - - - - - - - -
KNFDGABE_01518 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KNFDGABE_01519 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNFDGABE_01520 2.8e-162 ybbR - - S - - - YbbR-like protein
KNFDGABE_01521 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNFDGABE_01522 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
KNFDGABE_01523 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KNFDGABE_01524 7.55e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNFDGABE_01525 2.17e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KNFDGABE_01526 1.51e-132 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KNFDGABE_01527 2.92e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
KNFDGABE_01528 1.78e-113 - - - K - - - Acetyltransferase (GNAT) domain
KNFDGABE_01529 6.95e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
KNFDGABE_01530 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KNFDGABE_01531 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNFDGABE_01532 9.61e-137 - - - - - - - -
KNFDGABE_01533 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KNFDGABE_01534 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KNFDGABE_01535 2.22e-185 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
KNFDGABE_01536 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KNFDGABE_01537 0.0 eriC - - P ko:K03281 - ko00000 chloride
KNFDGABE_01538 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
KNFDGABE_01539 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KNFDGABE_01540 2.93e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNFDGABE_01541 4.41e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KNFDGABE_01542 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNFDGABE_01544 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNFDGABE_01545 1.67e-307 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
KNFDGABE_01546 1.83e-21 - - - - - - - -
KNFDGABE_01548 1.37e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KNFDGABE_01549 6.97e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KNFDGABE_01550 9.4e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KNFDGABE_01551 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
KNFDGABE_01552 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KNFDGABE_01553 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNFDGABE_01554 1.03e-19 - - - - - - - -
KNFDGABE_01555 4.17e-149 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
KNFDGABE_01556 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KNFDGABE_01557 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
KNFDGABE_01558 2e-206 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
KNFDGABE_01559 1.83e-259 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KNFDGABE_01560 8.29e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KNFDGABE_01561 4.77e-216 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
KNFDGABE_01562 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
KNFDGABE_01563 3.55e-175 lutC - - S ko:K00782 - ko00000 LUD domain
KNFDGABE_01564 7.6e-216 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KNFDGABE_01565 2.31e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KNFDGABE_01566 1.64e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNFDGABE_01567 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNFDGABE_01568 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KNFDGABE_01569 2.11e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
KNFDGABE_01570 2.62e-237 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNFDGABE_01571 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KNFDGABE_01572 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNFDGABE_01573 1.87e-151 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KNFDGABE_01574 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
KNFDGABE_01575 4.68e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KNFDGABE_01576 6.43e-273 - - - EGP - - - Major Facilitator
KNFDGABE_01577 9.88e-77 - - - K - - - Transcriptional regulator
KNFDGABE_01578 1.53e-52 - - - - - - - -
KNFDGABE_01579 0.0 ydaO - - E - - - amino acid
KNFDGABE_01580 0.0 - - - E - - - amino acid
KNFDGABE_01581 2.86e-102 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
KNFDGABE_01582 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KNFDGABE_01583 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNFDGABE_01585 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNFDGABE_01586 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KNFDGABE_01587 1.02e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNFDGABE_01588 1.31e-290 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KNFDGABE_01589 3.82e-183 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
KNFDGABE_01590 3.49e-175 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KNFDGABE_01591 7.35e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KNFDGABE_01592 1.64e-166 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNFDGABE_01593 9.67e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNFDGABE_01594 6.1e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
KNFDGABE_01595 2.19e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
KNFDGABE_01596 7.03e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KNFDGABE_01597 1.47e-218 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KNFDGABE_01598 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KNFDGABE_01599 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KNFDGABE_01600 3.02e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KNFDGABE_01601 1.34e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNFDGABE_01602 5.28e-76 yabA - - L - - - Involved in initiation control of chromosome replication
KNFDGABE_01603 5.49e-237 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KNFDGABE_01604 1.64e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
KNFDGABE_01605 3.41e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNFDGABE_01606 2.71e-51 - - - S - - - Protein of unknown function (DUF2508)
KNFDGABE_01607 4.05e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNFDGABE_01608 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNFDGABE_01609 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNFDGABE_01610 3.59e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KNFDGABE_01611 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KNFDGABE_01612 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNFDGABE_01613 1.14e-255 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNFDGABE_01614 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KNFDGABE_01615 2.66e-169 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KNFDGABE_01616 2.3e-128 - - - S - - - Protein of unknown function (DUF1700)
KNFDGABE_01617 1.14e-74 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
KNFDGABE_01618 1.2e-64 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KNFDGABE_01620 8.34e-65 - - - - - - - -
KNFDGABE_01621 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KNFDGABE_01622 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KNFDGABE_01623 7.29e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KNFDGABE_01624 2.29e-303 - - - M - - - Glycosyl transferase family group 2
KNFDGABE_01625 4.35e-108 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KNFDGABE_01626 9.63e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
KNFDGABE_01627 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KNFDGABE_01628 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNFDGABE_01629 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KNFDGABE_01630 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KNFDGABE_01631 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KNFDGABE_01632 3.02e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNFDGABE_01633 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KNFDGABE_01634 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KNFDGABE_01635 9.48e-262 yacL - - S - - - domain protein
KNFDGABE_01636 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNFDGABE_01637 1.39e-128 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
KNFDGABE_01638 4.04e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
KNFDGABE_01639 3.41e-160 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNFDGABE_01640 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KNFDGABE_01641 1.67e-178 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KNFDGABE_01642 9.69e-171 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01643 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_01644 9e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KNFDGABE_01645 3.63e-215 - - - I - - - alpha/beta hydrolase fold
KNFDGABE_01646 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KNFDGABE_01647 0.0 - - - S - - - Bacterial membrane protein, YfhO
KNFDGABE_01648 4.51e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
KNFDGABE_01649 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
KNFDGABE_01651 1.59e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KNFDGABE_01652 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
KNFDGABE_01653 4.33e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KNFDGABE_01654 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNFDGABE_01655 8.35e-164 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
KNFDGABE_01656 5.86e-167 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KNFDGABE_01657 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
KNFDGABE_01658 0.0 - - - EGP - - - Major Facilitator
KNFDGABE_01659 1.05e-143 - - - - - - - -
KNFDGABE_01662 2.91e-190 - - - S - - - Calcineurin-like phosphoesterase
KNFDGABE_01663 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
KNFDGABE_01666 1.19e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
KNFDGABE_01667 3.24e-77 - - - M - - - LPXTG-motif cell wall anchor domain protein
KNFDGABE_01668 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KNFDGABE_01669 1.92e-220 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KNFDGABE_01670 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KNFDGABE_01671 1.02e-314 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KNFDGABE_01672 2.18e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KNFDGABE_01673 1.91e-282 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KNFDGABE_01674 5.62e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNFDGABE_01675 1.56e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KNFDGABE_01676 2.93e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KNFDGABE_01677 4.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNFDGABE_01678 3.07e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KNFDGABE_01679 2.15e-75 - - - - - - - -
KNFDGABE_01681 5.53e-246 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KNFDGABE_01682 2.09e-37 - - - - - - - -
KNFDGABE_01683 2.6e-233 - - - I - - - Diacylglycerol kinase catalytic
KNFDGABE_01684 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
KNFDGABE_01685 2.21e-104 - - - - - - - -
KNFDGABE_01686 4.81e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KNFDGABE_01687 9.95e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KNFDGABE_01688 3.28e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
KNFDGABE_01689 2.59e-312 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KNFDGABE_01690 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KNFDGABE_01691 4.08e-62 yktA - - S - - - Belongs to the UPF0223 family
KNFDGABE_01692 6.8e-175 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
KNFDGABE_01693 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KNFDGABE_01694 9.19e-285 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KNFDGABE_01695 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
KNFDGABE_01696 3.93e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
KNFDGABE_01697 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNFDGABE_01698 2.58e-253 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KNFDGABE_01699 7.15e-140 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
KNFDGABE_01700 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KNFDGABE_01701 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KNFDGABE_01702 9.31e-193 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KNFDGABE_01703 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KNFDGABE_01704 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KNFDGABE_01705 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNFDGABE_01706 3.58e-208 - - - S - - - Tetratricopeptide repeat
KNFDGABE_01707 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNFDGABE_01708 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KNFDGABE_01709 5.06e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNFDGABE_01710 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KNFDGABE_01711 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
KNFDGABE_01712 4.93e-20 - - - - - - - -
KNFDGABE_01713 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KNFDGABE_01714 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNFDGABE_01715 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KNFDGABE_01716 2.24e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KNFDGABE_01717 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KNFDGABE_01718 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNFDGABE_01719 1.53e-122 - - - - - - - -
KNFDGABE_01721 1.25e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNFDGABE_01722 1.17e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
KNFDGABE_01723 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNFDGABE_01724 2.7e-47 ynzC - - S - - - UPF0291 protein
KNFDGABE_01725 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
KNFDGABE_01726 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KNFDGABE_01727 5.9e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
KNFDGABE_01728 9.65e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
KNFDGABE_01729 1.97e-231 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNFDGABE_01730 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KNFDGABE_01731 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNFDGABE_01732 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KNFDGABE_01733 8.54e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KNFDGABE_01734 3.03e-181 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNFDGABE_01735 4.1e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KNFDGABE_01736 2.83e-299 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KNFDGABE_01737 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNFDGABE_01738 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNFDGABE_01739 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KNFDGABE_01740 2.9e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KNFDGABE_01741 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
KNFDGABE_01742 1.61e-64 ylxQ - - J - - - ribosomal protein
KNFDGABE_01743 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNFDGABE_01744 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNFDGABE_01745 7.03e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNFDGABE_01746 9.36e-227 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KNFDGABE_01747 1.04e-83 - - - - - - - -
KNFDGABE_01748 1.13e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KNFDGABE_01749 4.3e-113 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KNFDGABE_01750 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KNFDGABE_01751 1.55e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KNFDGABE_01752 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KNFDGABE_01753 2.16e-286 int7 - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01754 1.63e-34 - - - - - - - -
KNFDGABE_01755 4.53e-89 - - - S - - - MTH538 TIR-like domain (DUF1863)
KNFDGABE_01756 2.89e-29 - - - S - - - Protein of unknown function (DUF4231)
KNFDGABE_01760 9.75e-101 - - - K - - - Peptidase S24-like
KNFDGABE_01761 9.06e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_01764 2.67e-22 - - - - - - - -
KNFDGABE_01767 1.73e-194 - - - L - - - DnaD domain protein
KNFDGABE_01768 1.31e-244 - - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_01769 7.78e-158 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
KNFDGABE_01771 5.43e-90 - - - - - - - -
KNFDGABE_01772 1.62e-173 - - - - - - - -
KNFDGABE_01779 7.73e-109 - - - S - - - Phage transcriptional regulator, ArpU family
KNFDGABE_01780 8.92e-06 - - - - - - - -
KNFDGABE_01782 2.32e-200 - - - L - - - HNH nucleases
KNFDGABE_01783 6.89e-102 - - - L - - - Phage terminase, small subunit
KNFDGABE_01784 0.0 terL - - S - - - overlaps another CDS with the same product name
KNFDGABE_01787 7.58e-306 - - - S - - - Phage portal protein
KNFDGABE_01788 2.79e-145 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
KNFDGABE_01789 1.81e-253 - - - S - - - Phage capsid family
KNFDGABE_01790 7.81e-88 - - - S - - - Phage gp6-like head-tail connector protein
KNFDGABE_01791 4.51e-54 - - - S - - - Phage head-tail joining protein
KNFDGABE_01792 6.21e-81 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KNFDGABE_01793 1.24e-96 - - - - - - - -
KNFDGABE_01794 3.28e-140 - - - - - - - -
KNFDGABE_01796 8.23e-28 - - - - - - - -
KNFDGABE_01797 0.0 - - - L - - - Phage tail tape measure protein TP901
KNFDGABE_01798 3.74e-204 - - - S - - - Phage tail protein
KNFDGABE_01799 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
KNFDGABE_01801 5.73e-121 - - - M - - - CotH kinase protein
KNFDGABE_01803 1.41e-27 - - - - - - - -
KNFDGABE_01804 8.31e-86 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
KNFDGABE_01805 9.8e-258 - - - M - - - hydrolase, family 25
KNFDGABE_01807 1.56e-110 - - - K - - - IrrE N-terminal-like domain
KNFDGABE_01808 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNFDGABE_01809 2.04e-254 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
KNFDGABE_01810 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KNFDGABE_01811 3.36e-77 - - - - - - - -
KNFDGABE_01812 3.27e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KNFDGABE_01813 8.25e-166 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KNFDGABE_01814 1.96e-71 - - - - - - - -
KNFDGABE_01815 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNFDGABE_01816 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KNFDGABE_01817 2.37e-217 - - - G - - - Phosphotransferase enzyme family
KNFDGABE_01818 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KNFDGABE_01819 4.45e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01820 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KNFDGABE_01821 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KNFDGABE_01822 1.11e-90 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
KNFDGABE_01823 2.62e-238 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KNFDGABE_01824 3.44e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KNFDGABE_01825 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KNFDGABE_01826 2.42e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KNFDGABE_01827 4.59e-222 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KNFDGABE_01828 1.83e-234 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KNFDGABE_01829 1.81e-108 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNFDGABE_01830 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KNFDGABE_01831 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNFDGABE_01832 2.5e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KNFDGABE_01833 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KNFDGABE_01834 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KNFDGABE_01835 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KNFDGABE_01836 2.54e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KNFDGABE_01837 1.82e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KNFDGABE_01838 1.25e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
KNFDGABE_01839 1.3e-95 - - - K - - - Transcriptional regulator
KNFDGABE_01840 4.72e-205 - - - - - - - -
KNFDGABE_01841 4.82e-167 idhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNFDGABE_01842 1.11e-214 - - - S ko:K07088 - ko00000 Membrane transport protein
KNFDGABE_01843 1.2e-110 - - - K - - - FCD
KNFDGABE_01844 6.85e-147 - - - C - - - Zinc-binding dehydrogenase
KNFDGABE_01845 1.7e-42 - - - C - - - Zinc-binding dehydrogenase
KNFDGABE_01846 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
KNFDGABE_01847 1.95e-270 - - - EGP - - - Major Facilitator
KNFDGABE_01848 1.25e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KNFDGABE_01849 1.16e-151 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KNFDGABE_01850 3.18e-11 - - - - - - - -
KNFDGABE_01851 1.78e-83 - - - - - - - -
KNFDGABE_01852 4.97e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KNFDGABE_01853 7.46e-106 uspA3 - - T - - - universal stress protein
KNFDGABE_01854 0.0 fusA1 - - J - - - elongation factor G
KNFDGABE_01855 2.09e-211 - - - GK - - - ROK family
KNFDGABE_01856 4.63e-309 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KNFDGABE_01857 3.16e-180 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
KNFDGABE_01858 4.11e-308 - - - E - - - amino acid
KNFDGABE_01859 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KNFDGABE_01860 5.23e-172 gntR - - K - - - UbiC transcription regulator-associated domain protein
KNFDGABE_01861 1.65e-113 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNFDGABE_01862 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNFDGABE_01863 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
KNFDGABE_01864 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01865 6.71e-241 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNFDGABE_01866 8.41e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KNFDGABE_01867 2.65e-195 - - - - - - - -
KNFDGABE_01868 1.77e-198 - - - G - - - Xylose isomerase domain protein TIM barrel
KNFDGABE_01869 4.81e-239 XK27_12525 - - S - - - AI-2E family transporter
KNFDGABE_01870 1.75e-169 XK27_07210 - - S - - - B3 4 domain
KNFDGABE_01871 6.71e-102 yybA - - K - - - Transcriptional regulator
KNFDGABE_01872 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
KNFDGABE_01873 8.08e-117 - - - GM - - - epimerase
KNFDGABE_01874 4.66e-197 - - - V - - - (ABC) transporter
KNFDGABE_01875 3.93e-306 yhdP - - S - - - Transporter associated domain
KNFDGABE_01876 4e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
KNFDGABE_01877 1.5e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
KNFDGABE_01878 3.59e-244 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
KNFDGABE_01879 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KNFDGABE_01880 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNFDGABE_01881 1.06e-53 - - - - - - - -
KNFDGABE_01882 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KNFDGABE_01883 1.57e-102 usp5 - - T - - - universal stress protein
KNFDGABE_01884 6.62e-105 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
KNFDGABE_01885 5.61e-292 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNFDGABE_01886 1.57e-135 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
KNFDGABE_01887 2.92e-233 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KNFDGABE_01888 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KNFDGABE_01889 5.13e-288 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNFDGABE_01890 8.7e-231 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
KNFDGABE_01891 4.87e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KNFDGABE_01892 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KNFDGABE_01893 1.21e-48 - - - - - - - -
KNFDGABE_01894 1.76e-68 - - - - - - - -
KNFDGABE_01895 1.58e-261 - - - - - - - -
KNFDGABE_01896 1.93e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNFDGABE_01897 5.87e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KNFDGABE_01898 3.58e-202 yvgN - - S - - - Aldo keto reductase
KNFDGABE_01899 9.11e-163 XK27_10500 - - K - - - response regulator
KNFDGABE_01900 6.14e-233 kinG - - T - - - Histidine kinase-like ATPases
KNFDGABE_01901 2.48e-174 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01902 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KNFDGABE_01903 5.97e-203 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KNFDGABE_01904 1.59e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KNFDGABE_01905 4.89e-70 - - - K - - - helix_turn_helix, mercury resistance
KNFDGABE_01906 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNFDGABE_01907 1.48e-252 - - - EGP - - - Major Facilitator
KNFDGABE_01908 1.8e-115 ymdB - - S - - - Macro domain protein
KNFDGABE_01909 3.49e-134 - - - K - - - Helix-turn-helix domain
KNFDGABE_01910 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KNFDGABE_01911 8.55e-64 - - - - - - - -
KNFDGABE_01912 1.14e-292 - - - S - - - Putative metallopeptidase domain
KNFDGABE_01913 2.25e-265 - - - S - - - associated with various cellular activities
KNFDGABE_01914 6.7e-154 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KNFDGABE_01915 1.92e-86 yeaO - - S - - - Protein of unknown function, DUF488
KNFDGABE_01917 2.58e-155 yrkL - - S - - - Flavodoxin-like fold
KNFDGABE_01918 6.7e-72 - - - - - - - -
KNFDGABE_01920 9.7e-84 - 2.1.1.72 - D ko:K03427 - ko00000,ko01000,ko02048 peptidase
KNFDGABE_01921 4.62e-67 - - - S - - - PD-(D/E)XK nuclease family transposase
KNFDGABE_01922 2.48e-66 - - - - - - - -
KNFDGABE_01924 1.3e-08 - - - D - - - nuclear chromosome segregation
KNFDGABE_01925 6.19e-20 - - - K - - - Helix-turn-helix domain
KNFDGABE_01927 8.4e-259 yngD - - S ko:K07097 - ko00000 DHHA1 domain
KNFDGABE_01928 1.1e-294 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
KNFDGABE_01929 5.41e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KNFDGABE_01930 3.46e-136 - - - NU - - - mannosyl-glycoprotein
KNFDGABE_01931 3.56e-187 - - - S - - - Putative ABC-transporter type IV
KNFDGABE_01932 0.0 - - - S - - - ABC transporter, ATP-binding protein
KNFDGABE_01933 1.62e-128 - - - K - - - Helix-turn-helix domain
KNFDGABE_01934 6.4e-65 - - - - - - - -
KNFDGABE_01935 8.66e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
KNFDGABE_01936 7.13e-134 - - - S - - - Protein of unknown function (DUF3278)
KNFDGABE_01938 2.71e-166 - - - M - - - PFAM NLP P60 protein
KNFDGABE_01939 7.76e-234 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KNFDGABE_01940 4.79e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KNFDGABE_01941 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01942 2.01e-121 - - - P - - - Cadmium resistance transporter
KNFDGABE_01943 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
KNFDGABE_01944 8.33e-79 - - - M - - - domain protein
KNFDGABE_01945 1.46e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
KNFDGABE_01946 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KNFDGABE_01947 5.37e-169 yceF - - P ko:K05794 - ko00000 membrane
KNFDGABE_01948 2.09e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KNFDGABE_01949 6.47e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KNFDGABE_01950 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNFDGABE_01951 1.6e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KNFDGABE_01952 5.46e-313 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KNFDGABE_01953 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
KNFDGABE_01954 1.92e-161 pgm3 - - G - - - phosphoglycerate mutase family
KNFDGABE_01955 2.07e-55 - - - - - - - -
KNFDGABE_01956 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KNFDGABE_01957 4.71e-263 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
KNFDGABE_01958 8.55e-187 - - - S - - - Alpha beta hydrolase
KNFDGABE_01959 1.33e-275 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KNFDGABE_01960 8.83e-128 - - - - - - - -
KNFDGABE_01962 1.03e-161 - - - M - - - ErfK YbiS YcfS YnhG
KNFDGABE_01963 0.0 - - - S - - - Putative peptidoglycan binding domain
KNFDGABE_01964 4.3e-142 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KNFDGABE_01965 6.28e-116 - - - - - - - -
KNFDGABE_01966 1.38e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KNFDGABE_01967 7.4e-275 yttB - - EGP - - - Major Facilitator
KNFDGABE_01968 1.52e-148 - - - - - - - -
KNFDGABE_01969 2.6e-33 - - - - - - - -
KNFDGABE_01970 3.24e-222 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
KNFDGABE_01971 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KNFDGABE_01972 1.36e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
KNFDGABE_01973 6.59e-48 - - - - - - - -
KNFDGABE_01974 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01975 1.49e-155 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_01976 1.96e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KNFDGABE_01977 9.16e-114 - - - K - - - transcriptional regulator (TetR family)
KNFDGABE_01978 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
KNFDGABE_01979 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KNFDGABE_01980 7.21e-75 - - - - - - - -
KNFDGABE_01981 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNFDGABE_01983 1.7e-27 - - - L ko:K07484 - ko00000 Transposase IS66 family
KNFDGABE_01985 6.1e-203 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KNFDGABE_01986 4.84e-170 - - - F - - - NUDIX domain
KNFDGABE_01987 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNFDGABE_01988 2.79e-132 pncA - - Q - - - Isochorismatase family
KNFDGABE_01989 4.25e-200 - - - O - - - ADP-ribosylglycohydrolase
KNFDGABE_01990 2.51e-94 - - - G - - - Belongs to the carbohydrate kinase PfkB family
KNFDGABE_01991 5.36e-50 hxlR - - K - - - regulation of RNA biosynthetic process
KNFDGABE_01992 6.07e-309 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
KNFDGABE_01993 8.61e-168 - - - IQ - - - dehydrogenase reductase
KNFDGABE_01994 9.18e-49 - - - - - - - -
KNFDGABE_01995 1.63e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
KNFDGABE_01996 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
KNFDGABE_01997 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KNFDGABE_01998 9.76e-233 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNFDGABE_02000 1.34e-127 - - - S ko:K07002 - ko00000 Serine hydrolase
KNFDGABE_02001 6.25e-83 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
KNFDGABE_02002 8.69e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNFDGABE_02004 7.38e-225 ydhF - - S - - - Aldo keto reductase
KNFDGABE_02005 1.78e-107 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
KNFDGABE_02006 0.0 - - - L - - - Helicase C-terminal domain protein
KNFDGABE_02008 3.3e-314 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
KNFDGABE_02009 1.52e-68 - - - S - - - Sugar efflux transporter for intercellular exchange
KNFDGABE_02010 9.01e-164 - - - - - - - -
KNFDGABE_02011 3e-167 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KNFDGABE_02012 0.0 cadA - - P - - - P-type ATPase
KNFDGABE_02013 4.81e-274 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
KNFDGABE_02014 4.44e-11 - - - - - - - -
KNFDGABE_02015 1.64e-200 - - - GM - - - NAD(P)H-binding
KNFDGABE_02016 5.27e-95 ywnA - - K - - - Transcriptional regulator
KNFDGABE_02017 1.77e-207 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
KNFDGABE_02018 2.74e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KNFDGABE_02019 1.23e-181 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_02020 1.32e-136 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
KNFDGABE_02021 3.67e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KNFDGABE_02022 0.0 eriC - - P ko:K03281 - ko00000 chloride
KNFDGABE_02023 1.44e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KNFDGABE_02024 1.24e-138 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KNFDGABE_02025 1.47e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNFDGABE_02026 6.16e-200 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KNFDGABE_02027 1.47e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KNFDGABE_02028 2.41e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
KNFDGABE_02029 1.3e-58 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
KNFDGABE_02030 1.15e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNFDGABE_02031 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
KNFDGABE_02032 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNFDGABE_02034 1.1e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KNFDGABE_02035 0.0 - - - L - - - DNA helicase
KNFDGABE_02036 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
KNFDGABE_02037 2.15e-234 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
KNFDGABE_02038 1.3e-241 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KNFDGABE_02039 7.81e-213 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KNFDGABE_02040 4.1e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KNFDGABE_02041 2.21e-227 - - - - - - - -
KNFDGABE_02042 1.14e-165 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
KNFDGABE_02044 2.25e-206 yunF - - F - - - Protein of unknown function DUF72
KNFDGABE_02045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNFDGABE_02046 5.93e-197 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
KNFDGABE_02047 8.23e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KNFDGABE_02048 8.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KNFDGABE_02049 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
KNFDGABE_02050 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KNFDGABE_02051 5.78e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KNFDGABE_02052 4.85e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KNFDGABE_02053 8.69e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
KNFDGABE_02054 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KNFDGABE_02055 4.57e-316 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNFDGABE_02056 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNFDGABE_02057 1.96e-101 - - - - - - - -
KNFDGABE_02058 3.93e-257 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KNFDGABE_02059 1.62e-190 yidA - - S - - - hydrolase
KNFDGABE_02060 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
KNFDGABE_02061 1.63e-195 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
KNFDGABE_02062 6.79e-91 ywiB - - S - - - Domain of unknown function (DUF1934)
KNFDGABE_02063 2.68e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KNFDGABE_02064 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KNFDGABE_02065 9.55e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNFDGABE_02066 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KNFDGABE_02067 2.64e-302 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNFDGABE_02068 3.75e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KNFDGABE_02069 1.23e-161 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
KNFDGABE_02070 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KNFDGABE_02071 1.84e-192 - - - G - - - Right handed beta helix region
KNFDGABE_02072 1.43e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNFDGABE_02073 6.47e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
KNFDGABE_02074 4.33e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
KNFDGABE_02075 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNFDGABE_02076 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
KNFDGABE_02077 2.61e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KNFDGABE_02078 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KNFDGABE_02079 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KNFDGABE_02080 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
KNFDGABE_02081 8.01e-211 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KNFDGABE_02082 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNFDGABE_02083 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNFDGABE_02084 4.49e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
KNFDGABE_02085 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNFDGABE_02086 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
KNFDGABE_02087 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KNFDGABE_02088 8.89e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNFDGABE_02089 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KNFDGABE_02090 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
KNFDGABE_02091 1.31e-307 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
KNFDGABE_02092 4.85e-187 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
KNFDGABE_02093 8.08e-147 - - - S - - - (CBS) domain
KNFDGABE_02094 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KNFDGABE_02095 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNFDGABE_02096 1.01e-52 yabO - - J - - - S4 domain protein
KNFDGABE_02097 1.44e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KNFDGABE_02098 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
KNFDGABE_02099 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KNFDGABE_02100 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KNFDGABE_02101 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNFDGABE_02102 1.6e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNFDGABE_02103 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNFDGABE_02104 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KNFDGABE_02106 3.85e-206 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KNFDGABE_02107 1.01e-58 ydeP - - K - - - Transcriptional regulator, HxlR family
KNFDGABE_02109 2.65e-07 - - - K - - - Helix-turn-helix domain
KNFDGABE_02110 1.98e-50 - - - D - - - nuclear chromosome segregation
KNFDGABE_02111 9.42e-99 - - - L - - - PFAM Integrase catalytic region
KNFDGABE_02112 1.68e-68 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
KNFDGABE_02121 4.73e-120 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
KNFDGABE_02130 1.36e-169 - - - S - - - Terminase-like family
KNFDGABE_02132 2.92e-65 - - - - - - - -
KNFDGABE_02134 5.13e-77 - - - - - - - -
KNFDGABE_02140 6.62e-11 - - - - - - - -
KNFDGABE_02141 1.48e-32 - - - O - - - gp58-like protein
KNFDGABE_02142 4e-31 - - - - - - - -
KNFDGABE_02146 3.73e-16 - - - S - - - COG5546 Small integral membrane protein
KNFDGABE_02149 2.25e-97 xerH - - L ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
KNFDGABE_02150 2.02e-74 - - - D - - - Phage-related minor tail protein
KNFDGABE_02153 9.84e-82 - - - - - - - -
KNFDGABE_02159 4.96e-140 - - - S - - - Glycosyl hydrolases family 25
KNFDGABE_02160 7.1e-60 - - - E - - - GDSL-like Lipase/Acylhydrolase
KNFDGABE_02162 3.42e-42 - - - S - - - CHC2 zinc finger
KNFDGABE_02163 2.88e-39 addB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
KNFDGABE_02165 7.26e-258 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KNFDGABE_02167 8.69e-73 - - - S - - - DNA ligase (ATP) activity
KNFDGABE_02168 1.23e-28 - - - S - - - Protein of unknown function (DUF1064)
KNFDGABE_02172 1.44e-75 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Methyltransferase
KNFDGABE_02173 2.74e-36 - - - L - - - C-5 cytosine-specific DNA methylase
KNFDGABE_02176 9.52e-17 - - - - - - - -
KNFDGABE_02179 8.06e-66 - 2.7.6.1 - EF ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNFDGABE_02180 5.45e-127 - - - S - - - nicotinate-nucleotide diphosphorylase (carboxylating) activity
KNFDGABE_02183 3.97e-43 pgpA - - I - - - Phosphatidylglycerophosphatase A
KNFDGABE_02185 8.28e-74 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Thymidine kinase
KNFDGABE_02186 9.37e-42 - - - M - - - LysM domain protein
KNFDGABE_02188 5.54e-101 - - - L - - - Integrase
KNFDGABE_02201 1.16e-71 - - - S - - - AAA domain
KNFDGABE_02208 1.37e-92 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
KNFDGABE_02222 7.21e-111 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
KNFDGABE_02230 3.17e-12 - - - S - - - electron carrier activity
KNFDGABE_02232 4.06e-64 - - - H - - - Nicotinamide mononucleotide transporter
KNFDGABE_02234 2.19e-102 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
KNFDGABE_02237 3.34e-140 - - - L - - - Helix-hairpin-helix containing domain
KNFDGABE_02240 1.61e-118 - - - L - - - DnaB-like helicase C terminal domain
KNFDGABE_02243 4.29e-65 - - - S - - - hydrolase activity
KNFDGABE_02249 5.76e-107 - - - L - - - Belongs to the 'phage' integrase family
KNFDGABE_02251 1.31e-58 - - - - - - - -
KNFDGABE_02252 2.7e-29 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KNFDGABE_02256 7.46e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_02257 1.45e-55 - - - S - - - Phage derived protein Gp49-like (DUF891)
KNFDGABE_02270 9.27e-15 - - - S - - - Antirestriction protein (ArdA)
KNFDGABE_02272 9.07e-150 - - - S - - - HAD hydrolase, family IA, variant
KNFDGABE_02273 0.0 yagE - - E - - - amino acid
KNFDGABE_02274 2.93e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KNFDGABE_02275 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KNFDGABE_02276 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KNFDGABE_02277 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNFDGABE_02278 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KNFDGABE_02279 1.44e-186 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KNFDGABE_02280 4.43e-183 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KNFDGABE_02281 4.21e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNFDGABE_02282 1.45e-295 - - - - - - - -
KNFDGABE_02283 1.62e-294 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KNFDGABE_02284 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
KNFDGABE_02285 1.46e-96 - - - F - - - Nudix hydrolase
KNFDGABE_02286 4.78e-135 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
KNFDGABE_02287 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KNFDGABE_02288 2.15e-37 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
KNFDGABE_02289 3.42e-195 - - - - - - - -
KNFDGABE_02290 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
KNFDGABE_02291 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
KNFDGABE_02292 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
KNFDGABE_02293 3.41e-232 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNFDGABE_02294 6.47e-10 - - - S - - - CsbD-like
KNFDGABE_02295 1.98e-42 - - - S - - - Transglycosylase associated protein
KNFDGABE_02296 2.63e-14 - - - - - - - -
KNFDGABE_02297 2.11e-290 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNFDGABE_02298 2.73e-161 pgm3 - - G - - - phosphoglycerate mutase
KNFDGABE_02299 3.83e-147 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KNFDGABE_02300 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KNFDGABE_02301 2.52e-300 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KNFDGABE_02302 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KNFDGABE_02303 2.73e-206 - - - EG - - - EamA-like transporter family
KNFDGABE_02304 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KNFDGABE_02305 8.32e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KNFDGABE_02306 6.18e-282 - - - S ko:K07133 - ko00000 cog cog1373
KNFDGABE_02308 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KNFDGABE_02309 4.72e-242 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KNFDGABE_02311 2.12e-62 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KNFDGABE_02312 9.32e-65 - - - - - - - -
KNFDGABE_02316 1.55e-09 - - - K - - - Helix-turn-helix XRE-family like proteins
KNFDGABE_02317 3.77e-29 - - - D - - - nuclear chromosome segregation
KNFDGABE_02319 1.7e-63 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
KNFDGABE_02322 3.42e-205 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KNFDGABE_02323 3.52e-59 ydeP - - K - - - Transcriptional regulator, HxlR family
KNFDGABE_02324 2.6e-200 - - - J - - - Methyltransferase
KNFDGABE_02325 1.81e-85 rmeB - - K - - - transcriptional regulator, MerR family
KNFDGABE_02326 5.49e-82 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KNFDGABE_02327 3.81e-129 - - - K - - - Cyclic nucleotide-binding domain
KNFDGABE_02328 2.47e-166 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
KNFDGABE_02329 7.19e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KNFDGABE_02330 5.58e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KNFDGABE_02331 1.79e-159 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KNFDGABE_02332 2.08e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNFDGABE_02333 3.86e-124 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
KNFDGABE_02334 6.14e-118 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
KNFDGABE_02335 7.76e-230 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KNFDGABE_02336 1.92e-206 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KNFDGABE_02337 2.86e-150 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
KNFDGABE_02338 8.35e-101 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KNFDGABE_02339 5.1e-118 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KNFDGABE_02340 5.09e-126 ywlG - - S - - - Belongs to the UPF0340 family
KNFDGABE_02341 5.75e-250 - - - EGP - - - Major Facilitator
KNFDGABE_02342 1.85e-153 - - - M - - - Lysin motif
KNFDGABE_02343 1.91e-103 - - - - - - - -
KNFDGABE_02344 3.31e-120 - - - K - - - PFAM GCN5-related N-acetyltransferase
KNFDGABE_02345 5.38e-120 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
KNFDGABE_02346 1.83e-259 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
KNFDGABE_02347 3.7e-19 - - - - - - - -
KNFDGABE_02348 5.8e-115 - - - S - - - Domain of unknown function (DUF4767)
KNFDGABE_02349 1.27e-249 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KNFDGABE_02350 2.26e-149 - - - S - - - Membrane
KNFDGABE_02351 1.06e-159 - - - O - - - Zinc-dependent metalloprotease
KNFDGABE_02352 3.82e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KNFDGABE_02353 1.51e-202 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KNFDGABE_02354 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KNFDGABE_02355 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)