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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IMFCPDME_00018	1.68e-157	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IMFCPDME_00019	2.49e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IMFCPDME_00020	8.92e-145	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
IMFCPDME_00021	1.36e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMFCPDME_00022	3.84e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IMFCPDME_00023	4.63e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IMFCPDME_00024	1.19e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IMFCPDME_00025	1.89e-40	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMFCPDME_00026	3.03e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IMFCPDME_00027	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMFCPDME_00028	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMFCPDME_00029	2.26e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IMFCPDME_00030	6.87e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMFCPDME_00031	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IMFCPDME_00032	9.12e-200	-	-	-	S	-	-	-	CHAP domain
IMFCPDME_00033	7.86e-304	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IMFCPDME_00034	6.02e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMFCPDME_00035	7.74e-257	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMFCPDME_00036	8.64e-179	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
IMFCPDME_00037	3.12e-46	-	-	-	-	-	-	-	-
IMFCPDME_00038	3.76e-185	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
IMFCPDME_00039	2.14e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMFCPDME_00040	4.86e-142	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMFCPDME_00041	5.29e-205	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
IMFCPDME_00042	6.74e-176	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IMFCPDME_00043	2e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IMFCPDME_00044	1.91e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMFCPDME_00045	8.62e-292	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
IMFCPDME_00046	1.86e-70	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IMFCPDME_00047	7.61e-139	mur1	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
IMFCPDME_00048	9.57e-184	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IMFCPDME_00049	2.46e-108	-	-	-	S	-	-	-	Bacterial inner membrane protein
IMFCPDME_00050	4.84e-158	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
IMFCPDME_00051	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IMFCPDME_00052	9.14e-267	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMFCPDME_00053	1.45e-280	-	-	-	S	-	-	-	membrane
IMFCPDME_00054	1.23e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IMFCPDME_00055	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IMFCPDME_00056	6.77e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
IMFCPDME_00057	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
IMFCPDME_00059	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_00060	5.03e-179	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMFCPDME_00062	1.09e-89	-	-	-	K	-	-	-	Helix-turn-helix
IMFCPDME_00063	7.9e-57	-	-	-	-	-	-	-	-
IMFCPDME_00065	2.35e-213	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
IMFCPDME_00066	2.32e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMFCPDME_00067	5.94e-207	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IMFCPDME_00068	1.45e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMFCPDME_00069	4.94e-282	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
IMFCPDME_00070	5.83e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IMFCPDME_00071	2.26e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
IMFCPDME_00072	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
IMFCPDME_00073	1.8e-167	-	-	-	S	-	-	-	Putative SAM-dependent methyltransferase
IMFCPDME_00074	7.29e-248	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMFCPDME_00075	1.95e-158	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IMFCPDME_00076	2.38e-273	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
IMFCPDME_00077	1.7e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMFCPDME_00078	7.84e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IMFCPDME_00079	9.29e-40	-	-	-	S	ko:K19165	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
IMFCPDME_00080	3.43e-64	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
IMFCPDME_00081	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00082	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00083	4.81e-252	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMFCPDME_00084	4.44e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IMFCPDME_00085	5.81e-252	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IMFCPDME_00086	5.4e-39	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
IMFCPDME_00088	2.82e-162	-	-	-	F	-	-	-	Phosphorylase superfamily
IMFCPDME_00089	5.36e-148	-	-	-	S	-	-	-	VIT family
IMFCPDME_00090	4.38e-162	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IMFCPDME_00091	3.12e-272	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IMFCPDME_00092	2.21e-255	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IMFCPDME_00094	1.57e-110	-	-	-	-	-	-	-	-
IMFCPDME_00095	1.02e-130	spoVK	-	-	O	-	-	-	stage V sporulation protein K
IMFCPDME_00097	1.48e-178	-	-	-	E	-	-	-	Alpha beta hydrolase
IMFCPDME_00098	1.2e-314	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMFCPDME_00099	7.15e-199	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IMFCPDME_00100	3.11e-220	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IMFCPDME_00101	7.64e-225	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IMFCPDME_00102	7.51e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IMFCPDME_00104	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IMFCPDME_00105	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMFCPDME_00106	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
IMFCPDME_00107	1.08e-43	-	-	-	-	-	-	-	-
IMFCPDME_00108	2.1e-151	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMFCPDME_00109	0.0	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
IMFCPDME_00110	2.97e-243	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IMFCPDME_00111	8.5e-316	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IMFCPDME_00112	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMFCPDME_00113	4.44e-218	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMFCPDME_00114	1.07e-262	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
IMFCPDME_00115	1.64e-39	pspC	-	-	KT	-	-	-	PspC domain protein
IMFCPDME_00116	1.43e-151	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IMFCPDME_00117	1.08e-102	-	-	-	K	-	-	-	hmm pf08876
IMFCPDME_00118	5.64e-294	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IMFCPDME_00119	3.39e-275	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
IMFCPDME_00120	1.48e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IMFCPDME_00121	3.16e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMFCPDME_00122	2.97e-30	-	-	-	-	-	-	-	-
IMFCPDME_00123	8.89e-288	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMFCPDME_00124	9.58e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IMFCPDME_00125	0.0	lysP	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IMFCPDME_00126	3.68e-229	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
IMFCPDME_00127	3.14e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
IMFCPDME_00128	4.35e-19	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
IMFCPDME_00129	5.42e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IMFCPDME_00130	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMFCPDME_00133	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMFCPDME_00134	1.75e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IMFCPDME_00135	3.44e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IMFCPDME_00138	9.51e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
IMFCPDME_00141	5.27e-140	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
IMFCPDME_00142	1.95e-150	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
IMFCPDME_00143	6.84e-227	-	-	-	S	-	-	-	oxidoreductase
IMFCPDME_00144	2.23e-65	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IMFCPDME_00145	7.82e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IMFCPDME_00146	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IMFCPDME_00147	1.51e-233	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMFCPDME_00148	3.31e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IMFCPDME_00149	2.2e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IMFCPDME_00150	1.09e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_00151	3.52e-101	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
IMFCPDME_00152	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IMFCPDME_00153	2.42e-12	-	-	-	-	-	-	-	-
IMFCPDME_00154	1.3e-193	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IMFCPDME_00155	1.72e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMFCPDME_00156	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMFCPDME_00157	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
IMFCPDME_00158	1.85e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMFCPDME_00159	4.63e-191	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
IMFCPDME_00160	1.31e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMFCPDME_00161	2.97e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IMFCPDME_00162	1.16e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMFCPDME_00163	1.45e-193	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IMFCPDME_00164	9.15e-132	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMFCPDME_00165	2.41e-280	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
IMFCPDME_00166	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IMFCPDME_00167	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IMFCPDME_00168	1.15e-104	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IMFCPDME_00169	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMFCPDME_00170	1.17e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
IMFCPDME_00171	4.73e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
IMFCPDME_00172	4.5e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
IMFCPDME_00173	2.19e-240	XK27_07735	-	-	S	-	-	-	YjbR
IMFCPDME_00174	6.56e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IMFCPDME_00175	1.2e-100	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IMFCPDME_00176	6.13e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IMFCPDME_00177	1.1e-34	WQ51_00785	-	-	-	-	-	-	-
IMFCPDME_00178	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IMFCPDME_00179	1.1e-275	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IMFCPDME_00180	2.48e-152	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IMFCPDME_00181	9.13e-203	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMFCPDME_00182	7.17e-258	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMFCPDME_00183	2.49e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMFCPDME_00184	3.06e-261	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IMFCPDME_00185	2.99e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
IMFCPDME_00186	1.65e-216	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IMFCPDME_00187	7.21e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IMFCPDME_00188	4.42e-111	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMFCPDME_00189	6.93e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IMFCPDME_00190	5.27e-316	msrR	-	-	K	-	-	-	Transcriptional regulator
IMFCPDME_00191	2.15e-194	ydiA	-	-	P	ko:K03304,ko:K11041	ko05150,map05150	ko00000,ko00001,ko02000,ko02042	C4-dicarboxylate transporter malic acid transport protein
IMFCPDME_00192	1.38e-250	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
IMFCPDME_00193	5.21e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
IMFCPDME_00194	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMFCPDME_00195	1.52e-123	-	-	-	S	ko:K07023	-	ko00000	HD domain
IMFCPDME_00196	2.31e-182	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMFCPDME_00197	1.74e-99	-	-	-	J	-	-	-	Acetyltransferase GNAT family
IMFCPDME_00198	8.28e-178	-	-	-	S	-	-	-	CAAX protease self-immunity
IMFCPDME_00199	8.42e-204	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IMFCPDME_00200	1.84e-56	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMFCPDME_00201	1.69e-260	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	transporter
IMFCPDME_00202	1.44e-192	ChZ00x2	-	-	S	-	-	-	EDD domain protein, DegV family
IMFCPDME_00203	2.83e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IMFCPDME_00204	6.51e-126	yagB	-	-	F	ko:K06950	-	ko00000	HD superfamily hydrolase
IMFCPDME_00205	2.08e-166	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
IMFCPDME_00206	6.34e-139	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
IMFCPDME_00207	0.0	-	-	-	M	-	-	-	family 8
IMFCPDME_00208	8.06e-75	-	-	-	M	-	-	-	family 8
IMFCPDME_00209	0.0	-	-	-	L	-	-	-	Transposase
IMFCPDME_00210	0.0	-	-	-	P	-	-	-	Major facilitator superfamily
IMFCPDME_00211	2.59e-125	tetR	-	-	K	-	-	-	transcriptional regulator
IMFCPDME_00212	6.16e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4300)
IMFCPDME_00213	1.15e-160	-	-	-	V	-	-	-	CAAX protease self-immunity
IMFCPDME_00214	5.92e-210	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMFCPDME_00215	1.23e-174	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IMFCPDME_00216	4.1e-228	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IMFCPDME_00217	1.3e-169	-	-	-	S	-	-	-	Putative esterase
IMFCPDME_00218	1.39e-105	-	-	-	Q	-	-	-	Methyltransferase domain
IMFCPDME_00219	2.31e-32	-	-	-	K	-	-	-	TetR family transcriptional regulator
IMFCPDME_00220	1.01e-42	-	-	-	K	-	-	-	Transcriptional regulator
IMFCPDME_00221	1.32e-63	-	-	-	-	-	-	-	-
IMFCPDME_00222	6.16e-158	-	-	-	V	-	-	-	CAAX protease self-immunity
IMFCPDME_00224	2.21e-30	-	-	-	M	-	-	-	Bacterial lipoprotein
IMFCPDME_00225	2.67e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
IMFCPDME_00226	1.22e-85	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
IMFCPDME_00228	4.36e-67	-	-	-	-	-	-	-	-
IMFCPDME_00229	1e-122	-	-	-	S	-	-	-	CAAX protease self-immunity
IMFCPDME_00230	4.02e-152	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IMFCPDME_00231	2.7e-132	-	-	-	-	-	-	-	-
IMFCPDME_00232	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate permease and related transporters (MFS superfamily)
IMFCPDME_00233	8.38e-192	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
IMFCPDME_00234	1.33e-198	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
IMFCPDME_00236	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
IMFCPDME_00237	1.02e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
IMFCPDME_00238	1.03e-211	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IMFCPDME_00239	1.11e-192	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMFCPDME_00240	9.98e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMFCPDME_00241	3.91e-90	ytxH	-	-	S	-	-	-	General stress protein
IMFCPDME_00243	1.75e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IMFCPDME_00244	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IMFCPDME_00245	3.79e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
IMFCPDME_00247	6e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
IMFCPDME_00248	8.94e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IMFCPDME_00249	2.54e-19	-	-	-	-	-	-	-	-
IMFCPDME_00251	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IMFCPDME_00252	6.06e-213	-	-	-	M	-	-	-	LysM domain
IMFCPDME_00253	1.22e-36	-	-	-	-	-	-	-	-
IMFCPDME_00254	3.26e-224	-	-	-	S	ko:K07025	-	ko00000	hydrolase
IMFCPDME_00255	2.41e-148	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
IMFCPDME_00256	1.23e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMFCPDME_00257	1.02e-191	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
IMFCPDME_00258	8.64e-36	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
IMFCPDME_00259	2.95e-201	hmpP2	-	-	G	-	-	-	hydrolase
IMFCPDME_00260	6.66e-144	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMFCPDME_00261	8.2e-268	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IMFCPDME_00262	1e-170	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IMFCPDME_00263	1.93e-60	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
IMFCPDME_00264	4.88e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
IMFCPDME_00265	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IMFCPDME_00266	2.98e-147	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
IMFCPDME_00267	6.46e-137	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IMFCPDME_00268	1.93e-99	-	-	-	-	-	-	-	-
IMFCPDME_00269	1.23e-111	-	-	-	-	-	-	-	-
IMFCPDME_00270	9.81e-95	-	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_00271	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IMFCPDME_00272	3.46e-104	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
IMFCPDME_00273	0.0	-	-	-	M	-	-	-	Right handed beta helix region
IMFCPDME_00274	3.19e-239	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IMFCPDME_00275	1.08e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IMFCPDME_00276	5.96e-190	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IMFCPDME_00277	1.4e-153	sirR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
IMFCPDME_00278	4.61e-216	psaA	-	-	P	ko:K11704,ko:K19971,ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IMFCPDME_00279	4.06e-171	mtsC	-	-	P	ko:K11705,ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type Mn2 Zn2 transport systems, permease components
IMFCPDME_00280	1.05e-166	sitB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMFCPDME_00281	9.64e-94	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
IMFCPDME_00282	6.55e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IMFCPDME_00283	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IMFCPDME_00284	5.47e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IMFCPDME_00285	1.59e-143	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IMFCPDME_00286	1.74e-238	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
IMFCPDME_00287	6.01e-135	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IMFCPDME_00288	3.05e-116	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IMFCPDME_00289	9.25e-108	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IMFCPDME_00290	1.86e-37	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
IMFCPDME_00291	8e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IMFCPDME_00292	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IMFCPDME_00293	5.19e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
IMFCPDME_00294	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMFCPDME_00295	2.59e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMFCPDME_00296	1.91e-188	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IMFCPDME_00297	8.58e-293	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IMFCPDME_00298	5.57e-305	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMFCPDME_00299	9.77e-160	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMFCPDME_00300	1.21e-130	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
IMFCPDME_00301	9.29e-40	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
IMFCPDME_00302	1.89e-186	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IMFCPDME_00303	2.89e-193	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IMFCPDME_00304	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMFCPDME_00305	4.51e-236	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMFCPDME_00306	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMFCPDME_00307	4.78e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IMFCPDME_00308	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMFCPDME_00309	2.46e-270	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IMFCPDME_00310	4.36e-284	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
IMFCPDME_00311	2.72e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
IMFCPDME_00312	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMFCPDME_00313	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IMFCPDME_00314	6.48e-207	XK27_05670	-	-	S	ko:K07017	-	ko00000	Putative esterase
IMFCPDME_00315	4.54e-197	XK27_05675	-	-	S	-	-	-	Esterase
IMFCPDME_00316	8.51e-289	XK27_05680	-	-	M	-	-	-	carbamoylphosphate synthase large subunit
IMFCPDME_00317	4.34e-241	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IMFCPDME_00318	5.27e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IMFCPDME_00319	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
IMFCPDME_00320	7.55e-53	-	-	-	S	-	-	-	yiaA/B two helix domain
IMFCPDME_00321	2.22e-171	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
IMFCPDME_00322	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMFCPDME_00323	3.57e-193	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IMFCPDME_00324	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
IMFCPDME_00325	1.6e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMFCPDME_00326	3.46e-216	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_00327	1.85e-315	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMFCPDME_00328	9.06e-87	mesH	-	-	S	-	-	-	GtrA-like protein
IMFCPDME_00329	9.32e-154	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IMFCPDME_00330	1.06e-185	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMFCPDME_00331	6.54e-187	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
IMFCPDME_00332	1.38e-254	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
IMFCPDME_00333	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
IMFCPDME_00334	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMFCPDME_00335	3.91e-142	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IMFCPDME_00336	3.86e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IMFCPDME_00339	1.97e-278	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IMFCPDME_00340	2.61e-183	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IMFCPDME_00341	1.1e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IMFCPDME_00342	5.5e-155	-	-	-	S	-	-	-	tigr01906
IMFCPDME_00343	9.45e-181	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
IMFCPDME_00344	1.13e-198	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
IMFCPDME_00345	1.82e-80	XK27_08085	-	-	-	-	-	-	-
IMFCPDME_00346	1.13e-247	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMFCPDME_00347	1.02e-231	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMFCPDME_00348	1.98e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IMFCPDME_00349	8.41e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMFCPDME_00350	4.76e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IMFCPDME_00351	1.41e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMFCPDME_00352	4.13e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMFCPDME_00353	2.29e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IMFCPDME_00354	6.01e-80	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMFCPDME_00355	1.8e-66	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
IMFCPDME_00358	6.26e-131	XK27_05505	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_00359	2.06e-186	-	-	-	P	-	-	-	molecular chaperone
IMFCPDME_00360	4.62e-171	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
IMFCPDME_00361	1.23e-230	-	-	-	M	-	-	-	glycosyl transferase family 2
IMFCPDME_00362	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
IMFCPDME_00363	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
IMFCPDME_00364	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
IMFCPDME_00365	1.74e-296	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IMFCPDME_00366	9.09e-315	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMFCPDME_00367	2.17e-146	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
IMFCPDME_00368	5.18e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IMFCPDME_00369	5e-176	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IMFCPDME_00370	1.53e-88	GnaT	2.5.1.16	-	K	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferase
IMFCPDME_00371	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
IMFCPDME_00372	8.79e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMFCPDME_00373	6.91e-233	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMFCPDME_00374	3.15e-163	dnaD	-	-	-	ko:K02086	-	ko00000	-
IMFCPDME_00375	1.84e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMFCPDME_00377	2.66e-298	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMFCPDME_00378	3.47e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMFCPDME_00379	1.24e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IMFCPDME_00380	2.58e-188	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IMFCPDME_00381	3.09e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IMFCPDME_00382	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IMFCPDME_00383	8.33e-192	WQ51_01275	-	-	S	-	-	-	DegV family
IMFCPDME_00384	4.73e-208	XK27_03630	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
IMFCPDME_00385	5.77e-127	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_00386	3.1e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMFCPDME_00387	0.0	-	-	-	L	-	-	-	Transposase
IMFCPDME_00388	1.44e-228	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
IMFCPDME_00389	1.24e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMFCPDME_00390	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMFCPDME_00391	1.36e-241	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IMFCPDME_00392	1.41e-49	ysdA	-	-	L	-	-	-	Membrane
IMFCPDME_00393	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMFCPDME_00394	5.58e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMFCPDME_00395	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IMFCPDME_00396	2.33e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IMFCPDME_00397	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IMFCPDME_00399	1.01e-230	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IMFCPDME_00400	1.37e-190	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IMFCPDME_00401	9.34e-175	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00402	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMFCPDME_00403	1.2e-190	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Esterase
IMFCPDME_00404	3.8e-163	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
IMFCPDME_00405	6.66e-24	XK27_08880	-	-	-	-	-	-	-
IMFCPDME_00406	2.45e-98	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IMFCPDME_00407	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
IMFCPDME_00408	1.22e-53	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
IMFCPDME_00409	5.81e-272	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter ClC family
IMFCPDME_00410	2.33e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IMFCPDME_00413	9.42e-28	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IMFCPDME_00414	6.64e-205	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMFCPDME_00415	3.2e-116	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IMFCPDME_00416	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMFCPDME_00417	3.24e-221	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IMFCPDME_00418	2.45e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMFCPDME_00419	3.97e-276	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IMFCPDME_00420	1.04e-176	-	-	-	-	-	-	-	-
IMFCPDME_00422	0.0	ydaM	-	-	M	-	-	-	Glycosyltransferases, probably involved in cell wall biogenesis
IMFCPDME_00423	3.91e-268	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IMFCPDME_00425	2.5e-297	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMFCPDME_00426	1.43e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
IMFCPDME_00427	1.05e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IMFCPDME_00428	1.75e-143	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IMFCPDME_00429	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_00430	8.27e-186	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IMFCPDME_00431	1.1e-179	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_00432	1.44e-165	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCPDME_00433	2.01e-281	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMFCPDME_00434	2.52e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
IMFCPDME_00435	2.68e-75	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
IMFCPDME_00436	4.12e-275	murM	2.3.2.10	-	V	ko:K05363	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
IMFCPDME_00437	1.68e-185	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
IMFCPDME_00438	2.6e-199	XK27_00115	-	-	K	-	-	-	Acetyltransferase GNAT family
IMFCPDME_00439	5.87e-179	-	-	-	F	-	-	-	Phosphorylase superfamily
IMFCPDME_00440	2.05e-90	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IMFCPDME_00441	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
IMFCPDME_00442	7.68e-172	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IMFCPDME_00443	2.83e-209	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IMFCPDME_00444	3.54e-262	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMFCPDME_00445	1.08e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMFCPDME_00446	8.67e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IMFCPDME_00447	8.45e-211	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IMFCPDME_00448	3.39e-118	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
IMFCPDME_00449	6.65e-236	XK27_05220	-	-	S	-	-	-	permease
IMFCPDME_00450	2.75e-287	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
IMFCPDME_00451	3.24e-126	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IMFCPDME_00452	0.0	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
IMFCPDME_00453	1.48e-290	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IMFCPDME_00454	1.47e-115	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
IMFCPDME_00455	3.71e-29	-	-	-	M	-	-	-	LysM domain
IMFCPDME_00456	2.39e-155	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IMFCPDME_00457	1.1e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMFCPDME_00458	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IMFCPDME_00459	1.49e-72	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMFCPDME_00460	4.37e-100	XK27_03610	-	-	K	-	-	-	Gnat family
IMFCPDME_00461	1.02e-114	yybC	-	-	-	-	-	-	-
IMFCPDME_00462	1.38e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IMFCPDME_00463	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
IMFCPDME_00464	2.28e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IMFCPDME_00465	5.95e-305	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IMFCPDME_00466	3.02e-171	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
IMFCPDME_00467	2.45e-150	capA	-	-	M	-	-	-	biosynthesis protein
IMFCPDME_00468	1.34e-156	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
IMFCPDME_00469	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IMFCPDME_00470	2.56e-163	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IMFCPDME_00471	4.56e-206	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
IMFCPDME_00472	1.47e-210	-	-	-	S	-	-	-	Glycosyl transferase family 2
IMFCPDME_00473	2.62e-262	-	-	-	M	-	-	-	glycosyl transferase group 1
IMFCPDME_00474	4.69e-104	-	-	-	-	-	-	-	-
IMFCPDME_00475	8.26e-219	galnac-T15	-	-	S	ko:K07011	-	ko00000	glycosyl transferase family 2
IMFCPDME_00476	5.72e-263	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IMFCPDME_00477	9.44e-194	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IMFCPDME_00478	1.01e-142	XK27_06100	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IMFCPDME_00479	1.52e-137	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IMFCPDME_00480	2.05e-143	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IMFCPDME_00481	2.04e-255	XK27_12525	-	-	S	-	-	-	hmm pf01594
IMFCPDME_00482	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IMFCPDME_00483	2.35e-52	-	-	-	S	-	-	-	granule-associated protein
IMFCPDME_00484	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
IMFCPDME_00485	1.01e-135	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
IMFCPDME_00486	1.64e-204	-	-	-	S	-	-	-	Phospholipase, patatin family
IMFCPDME_00487	0.0	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
IMFCPDME_00488	6.92e-280	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMFCPDME_00489	2.71e-152	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMFCPDME_00490	3.58e-301	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IMFCPDME_00491	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IMFCPDME_00492	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
IMFCPDME_00493	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	An automated process has identified a potential problem with this gene model
IMFCPDME_00494	1.79e-138	casB	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasB
IMFCPDME_00495	2.12e-234	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
IMFCPDME_00496	2.58e-174	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasD
IMFCPDME_00497	1.1e-144	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasE
IMFCPDME_00498	2.88e-220	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IMFCPDME_00499	1.54e-218	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated endoribonuclease Cas2
IMFCPDME_00500	7.23e-300	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_00501	2.55e-275	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_00502	4.34e-236	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IMFCPDME_00503	6.61e-231	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IMFCPDME_00504	3.79e-273	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMFCPDME_00505	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IMFCPDME_00506	0.0	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
IMFCPDME_00507	5.69e-111	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
IMFCPDME_00508	0.0	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
IMFCPDME_00509	1.31e-164	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMFCPDME_00510	2.69e-199	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMFCPDME_00511	5e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_00512	3.11e-231	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
IMFCPDME_00513	7.66e-193	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IMFCPDME_00514	2.38e-293	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
IMFCPDME_00515	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IMFCPDME_00516	5.04e-154	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMFCPDME_00517	9.68e-34	-	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IMFCPDME_00518	2.27e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMFCPDME_00519	2.6e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_00520	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_00521	2.38e-291	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMFCPDME_00522	8.48e-221	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IMFCPDME_00523	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IMFCPDME_00524	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IMFCPDME_00527	3.58e-238	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IMFCPDME_00528	3.08e-247	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IMFCPDME_00529	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IMFCPDME_00530	9.39e-149	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IMFCPDME_00531	2.13e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMFCPDME_00532	7.48e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMFCPDME_00533	7.33e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
IMFCPDME_00534	7.67e-200	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IMFCPDME_00535	2.31e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
IMFCPDME_00536	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IMFCPDME_00537	2.21e-182	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IMFCPDME_00538	8.42e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IMFCPDME_00539	1.03e-92	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IMFCPDME_00540	9.3e-221	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IMFCPDME_00541	1.75e-187	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMFCPDME_00542	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
IMFCPDME_00543	8.72e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
IMFCPDME_00544	9.88e-145	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IMFCPDME_00545	1e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMFCPDME_00546	5.18e-77	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IMFCPDME_00547	4.36e-35	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IMFCPDME_00548	2.32e-304	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
IMFCPDME_00549	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IMFCPDME_00550	2.03e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
IMFCPDME_00551	1.19e-314	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMFCPDME_00552	7.19e-218	bglC	-	-	K	-	-	-	Transcriptional regulator
IMFCPDME_00553	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IMFCPDME_00554	4.63e-105	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_00555	1.13e-190	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IMFCPDME_00556	1.11e-303	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IMFCPDME_00557	3.05e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMFCPDME_00558	8.35e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IMFCPDME_00559	3.39e-226	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IMFCPDME_00560	2.69e-186	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IMFCPDME_00561	1.13e-120	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
IMFCPDME_00562	1.96e-183	-	-	-	S	-	-	-	TraX protein
IMFCPDME_00563	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IMFCPDME_00564	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_00565	1.83e-297	dinF	-	-	V	-	-	-	Mate efflux family protein
IMFCPDME_00566	7.15e-230	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
IMFCPDME_00567	9.44e-200	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
IMFCPDME_00568	1.62e-141	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
IMFCPDME_00569	4.05e-54	-	-	-	F	-	-	-	Phosphorylase superfamily
IMFCPDME_00570	1.24e-237	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
IMFCPDME_00571	2.4e-252	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IMFCPDME_00572	1.42e-192	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IMFCPDME_00573	1.54e-136	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
IMFCPDME_00574	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
IMFCPDME_00576	6.55e-95	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IMFCPDME_00577	2.93e-145	-	-	-	L	ko:K07498	-	ko00000	DDE domain
IMFCPDME_00578	7.14e-186	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMFCPDME_00579	1.03e-200	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_00580	1.99e-168	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IMFCPDME_00581	8.69e-127	-	2.7.7.65	-	T	ko:K16923,ko:K18967	-	ko00000,ko00002,ko01000,ko02000	phosphorelay sensor kinase activity
IMFCPDME_00582	1.73e-177	-	-	-	S	-	-	-	Phenazine biosynthesis protein
IMFCPDME_00583	5.45e-138	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
IMFCPDME_00584	0.0	proWX	-	-	P	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMFCPDME_00585	2.88e-164	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00586	1.52e-216	-	-	-	C	-	-	-	alcohol dehydrogenase
IMFCPDME_00587	6.27e-174	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
IMFCPDME_00588	1.78e-92	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IMFCPDME_00589	3.13e-101	-	-	-	S	-	-	-	Macro domain
IMFCPDME_00590	8.56e-121	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IMFCPDME_00591	3.1e-54	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
IMFCPDME_00592	1.9e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
IMFCPDME_00593	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IMFCPDME_00596	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IMFCPDME_00598	2.48e-25	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IMFCPDME_00599	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
IMFCPDME_00600	1.24e-176	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
IMFCPDME_00601	3.59e-223	-	-	-	P	-	-	-	Chloride transporter, ClC family
IMFCPDME_00602	1.69e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMFCPDME_00603	3.54e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
IMFCPDME_00604	2.11e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMFCPDME_00605	3.96e-154	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMFCPDME_00606	0.0	-	-	-	V	ko:K13732	ko05100,map05100	ko00000,ko00001	Glucan-binding protein C
IMFCPDME_00607	2.02e-91	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IMFCPDME_00608	1.11e-284	XK27_05470	-	-	E	-	-	-	Methionine synthase
IMFCPDME_00609	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMFCPDME_00610	5.3e-284	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IMFCPDME_00611	1.98e-155	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IMFCPDME_00613	4.97e-68	-	-	-	V	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IMFCPDME_00614	2.09e-106	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IMFCPDME_00615	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMFCPDME_00616	1.92e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IMFCPDME_00617	1.11e-209	-	-	-	GK	-	-	-	ROK family
IMFCPDME_00618	1.81e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMFCPDME_00619	1.4e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMFCPDME_00620	2.14e-164	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IMFCPDME_00621	1.58e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IMFCPDME_00622	1.33e-111	-	-	-	-	ko:K16788	-	ko00000,ko02000	-
IMFCPDME_00623	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMFCPDME_00624	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMFCPDME_00625	3.02e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IMFCPDME_00626	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IMFCPDME_00627	4.58e-127	-	-	-	-	-	-	-	-
IMFCPDME_00628	3.07e-71	-	-	-	S	-	-	-	ABC-2 type transporter
IMFCPDME_00629	5.44e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IMFCPDME_00630	1.45e-186	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IMFCPDME_00631	5.22e-174	fasA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
IMFCPDME_00632	1.33e-311	fasC	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_00633	1.43e-265	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_00634	2.99e-193	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_00635	1.18e-292	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
IMFCPDME_00636	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMFCPDME_00637	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IMFCPDME_00638	1.37e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IMFCPDME_00639	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMFCPDME_00640	4.66e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IMFCPDME_00641	4.77e-116	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IMFCPDME_00642	2.91e-163	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IMFCPDME_00643	1.08e-287	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMFCPDME_00644	8.52e-96	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
IMFCPDME_00645	4.94e-103	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IMFCPDME_00646	3.33e-140	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
IMFCPDME_00647	3.61e-307	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
IMFCPDME_00648	4.28e-181	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
IMFCPDME_00649	1.37e-123	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
IMFCPDME_00650	2.42e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IMFCPDME_00651	9.64e-219	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IMFCPDME_00652	2.2e-150	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IMFCPDME_00653	2.71e-120	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMFCPDME_00654	2.31e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IMFCPDME_00655	3.08e-109	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IMFCPDME_00656	1.5e-179	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant
IMFCPDME_00657	1.47e-205	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
IMFCPDME_00661	1.2e-117	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IMFCPDME_00662	3.13e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMFCPDME_00663	3.2e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
IMFCPDME_00664	2.24e-239	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
IMFCPDME_00665	4.53e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMFCPDME_00667	2.86e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IMFCPDME_00669	9.76e-256	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IMFCPDME_00670	2.36e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMFCPDME_00671	7.45e-131	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
IMFCPDME_00673	9.28e-124	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IMFCPDME_00674	1.05e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
IMFCPDME_00675	7.46e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMFCPDME_00676	1.38e-225	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IMFCPDME_00677	1e-16	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IMFCPDME_00678	6.52e-93	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
IMFCPDME_00679	3.03e-22	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
IMFCPDME_00680	9.78e-92	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
IMFCPDME_00681	4.5e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IMFCPDME_00682	3.79e-185	cglB	-	-	U	ko:K02244	-	ko00000,ko00002,ko02044	protein transport across the cell outer membrane
IMFCPDME_00683	1.55e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMFCPDME_00684	1.37e-91	-	-	-	S	-	-	-	cog cog4699
IMFCPDME_00685	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMFCPDME_00686	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMFCPDME_00687	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IMFCPDME_00688	1.36e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMFCPDME_00689	2.99e-247	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMFCPDME_00690	7.09e-101	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IMFCPDME_00691	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IMFCPDME_00692	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IMFCPDME_00693	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IMFCPDME_00694	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
IMFCPDME_00695	8.15e-285	norN	-	-	V	-	-	-	Mate efflux family protein
IMFCPDME_00696	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IMFCPDME_00697	6.92e-05	yebC	-	-	M	-	-	-	Membrane
IMFCPDME_00699	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IMFCPDME_00700	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IMFCPDME_00701	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IMFCPDME_00702	0.0	treP	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_00703	1.65e-151	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
IMFCPDME_00704	6.51e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IMFCPDME_00707	4.93e-211	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
IMFCPDME_00709	4.77e-306	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
IMFCPDME_00710	3.03e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
IMFCPDME_00711	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMFCPDME_00712	1.63e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMFCPDME_00713	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMFCPDME_00714	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IMFCPDME_00715	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMFCPDME_00716	4.85e-151	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IMFCPDME_00717	8.65e-293	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IMFCPDME_00718	6.96e-84	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IMFCPDME_00719	9.89e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
IMFCPDME_00720	7e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMFCPDME_00721	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMFCPDME_00722	5.88e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMFCPDME_00723	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMFCPDME_00724	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMFCPDME_00725	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMFCPDME_00726	5.67e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMFCPDME_00727	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMFCPDME_00728	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMFCPDME_00729	6.2e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IMFCPDME_00730	4.35e-94	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMFCPDME_00731	9.44e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMFCPDME_00732	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMFCPDME_00733	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMFCPDME_00734	5.06e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMFCPDME_00735	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IMFCPDME_00736	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IMFCPDME_00737	3.17e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMFCPDME_00738	4.29e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IMFCPDME_00739	2.95e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IMFCPDME_00740	3.49e-139	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IMFCPDME_00741	7.8e-42	adhP	1.1.1.1	-	P	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IMFCPDME_00742	1.55e-74	adhP	1.1.1.1	-	P	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IMFCPDME_00743	4.33e-62	-	-	-	-	-	-	-	-
IMFCPDME_00744	1.24e-67	-	-	-	-	-	-	-	-
IMFCPDME_00745	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMFCPDME_00746	1.35e-203	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IMFCPDME_00747	7.5e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_00748	1.17e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_00749	7.1e-78	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
IMFCPDME_00750	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IMFCPDME_00751	5.13e-213	cpsY	-	-	K	-	-	-	Transcriptional regulator
IMFCPDME_00752	3.54e-167	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
IMFCPDME_00753	1.24e-216	yeiH	-	-	S	-	-	-	Membrane
IMFCPDME_00756	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IMFCPDME_00757	1.49e-186	XK27_10720	-	-	D	-	-	-	peptidase activity
IMFCPDME_00758	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IMFCPDME_00759	1.99e-206	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IMFCPDME_00760	1.57e-234	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IMFCPDME_00761	1.78e-210	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IMFCPDME_00762	2.2e-175	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
IMFCPDME_00763	1.1e-300	-	-	-	D	-	-	-	nuclear chromosome segregation
IMFCPDME_00764	5.6e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IMFCPDME_00765	3.04e-173	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IMFCPDME_00766	7.04e-107	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IMFCPDME_00767	4.52e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IMFCPDME_00768	9.11e-84	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
IMFCPDME_00770	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IMFCPDME_00771	2.66e-270	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IMFCPDME_00772	4.43e-105	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_00773	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IMFCPDME_00774	1.78e-154	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IMFCPDME_00775	8.2e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IMFCPDME_00776	9.03e-236	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IMFCPDME_00777	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMFCPDME_00778	2.1e-246	-	-	-	S	ko:K07335	-	ko00000	membrane
IMFCPDME_00779	1.6e-89	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IMFCPDME_00780	1.74e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMFCPDME_00781	6.58e-295	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IMFCPDME_00782	3.08e-134	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
IMFCPDME_00783	2.2e-219	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IMFCPDME_00784	4.36e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IMFCPDME_00785	1.18e-308	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMFCPDME_00786	9.74e-154	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCPDME_00787	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IMFCPDME_00788	5.83e-152	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
IMFCPDME_00789	1.43e-118	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMFCPDME_00790	6.16e-120	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IMFCPDME_00791	1.21e-117	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_00792	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IMFCPDME_00793	5.14e-212	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
IMFCPDME_00794	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMFCPDME_00796	9.95e-180	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
IMFCPDME_00797	3.16e-230	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
IMFCPDME_00798	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
IMFCPDME_00799	1.04e-309	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IMFCPDME_00800	7.07e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMFCPDME_00801	3.07e-303	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
IMFCPDME_00802	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMFCPDME_00803	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_00804	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_00805	1.69e-125	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
IMFCPDME_00806	7.41e-229	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
IMFCPDME_00807	1.06e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMFCPDME_00808	2.53e-140	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IMFCPDME_00809	3.56e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IMFCPDME_00810	7.92e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMFCPDME_00811	4.74e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IMFCPDME_00812	1.58e-240	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IMFCPDME_00813	5.51e-197	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
IMFCPDME_00814	3.53e-226	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
IMFCPDME_00815	2.58e-226	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IMFCPDME_00816	3.52e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
IMFCPDME_00817	1.28e-293	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
IMFCPDME_00818	5.67e-211	ypuA	-	-	S	-	-	-	secreted protein
IMFCPDME_00819	1.5e-93	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IMFCPDME_00820	3.78e-170	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
IMFCPDME_00821	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMFCPDME_00822	7.17e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IMFCPDME_00823	0.0	noxE	-	-	P	-	-	-	NADH oxidase
IMFCPDME_00824	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
IMFCPDME_00825	6.54e-108	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IMFCPDME_00826	1.49e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
IMFCPDME_00827	1.2e-111	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IMFCPDME_00829	2.54e-305	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMFCPDME_00830	6.52e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
IMFCPDME_00832	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMFCPDME_00833	3.73e-121	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMFCPDME_00834	1.38e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMFCPDME_00835	7.46e-32	WQ51_00220	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
IMFCPDME_00836	1.81e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
IMFCPDME_00837	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IMFCPDME_00838	2.63e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IMFCPDME_00839	8.96e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMFCPDME_00840	5.02e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMFCPDME_00841	1.98e-154	-	-	-	L	-	-	-	DNA alkylation repair enzyme
IMFCPDME_00842	0.0	clsA_1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMFCPDME_00843	8.38e-113	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
IMFCPDME_00844	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMFCPDME_00845	2.22e-198	-	-	-	L	-	-	-	PFAM Integrase catalytic region
IMFCPDME_00846	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IMFCPDME_00847	2.01e-69	-	-	-	-	-	-	-	-
IMFCPDME_00848	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IMFCPDME_00849	3.16e-167	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
IMFCPDME_00850	1.14e-156	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IMFCPDME_00851	4.58e-189	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IMFCPDME_00852	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IMFCPDME_00853	3.18e-209	yjlA	-	-	EG	-	-	-	membrane
IMFCPDME_00854	8.06e-104	-	-	-	S	-	-	-	RDD family
IMFCPDME_00855	4.8e-203	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IMFCPDME_00856	1.61e-64	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	general stress protein
IMFCPDME_00857	0.0	prtA	-	-	O	-	-	-	Belongs to the peptidase S8 family
IMFCPDME_00858	2.41e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IMFCPDME_00859	5.21e-181	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IMFCPDME_00860	1.8e-182	M1-956	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IMFCPDME_00861	1.06e-235	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00862	1.1e-129	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMFCPDME_00863	9.36e-236	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMFCPDME_00864	2.78e-168	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IMFCPDME_00865	1.77e-204	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
IMFCPDME_00868	3.06e-212	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
IMFCPDME_00869	9.95e-108	-	-	-	F	-	-	-	cytidine deaminase activity
IMFCPDME_00870	2.57e-148	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transporter
IMFCPDME_00871	3.83e-199	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00874	1.67e-120	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
IMFCPDME_00875	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IMFCPDME_00876	1.94e-167	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IMFCPDME_00877	1.02e-198	-	-	-	T	-	-	-	Histidine kinase
IMFCPDME_00878	3.03e-158	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCPDME_00879	5.11e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IMFCPDME_00880	2.43e-283	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
IMFCPDME_00881	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
IMFCPDME_00882	1.31e-182	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IMFCPDME_00883	5.45e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IMFCPDME_00885	9.42e-232	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMFCPDME_00886	3.16e-296	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IMFCPDME_00887	1.24e-230	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IMFCPDME_00888	1.03e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IMFCPDME_00889	1.68e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IMFCPDME_00890	1.3e-32	-	-	-	S	-	-	-	CsbD-like
IMFCPDME_00891	5.29e-308	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
IMFCPDME_00892	1.44e-297	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IMFCPDME_00893	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00894	3.26e-176	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_00895	8.21e-148	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
IMFCPDME_00896	1.12e-146	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_00897	3.34e-211	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IMFCPDME_00898	3.93e-227	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
IMFCPDME_00899	1.96e-108	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IMFCPDME_00900	1.39e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IMFCPDME_00901	9.81e-260	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IMFCPDME_00902	4.82e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00903	3.79e-125	-	-	-	K	-	-	-	WHG domain
IMFCPDME_00904	3.21e-214	ydhF	-	-	S	-	-	-	Aldo keto reductase
IMFCPDME_00906	6.89e-37	XK27_07105	-	-	K	ko:K07729	-	ko00000,ko03000	transcriptional
IMFCPDME_00907	1.34e-42	-	-	-	-	-	-	-	-
IMFCPDME_00908	9.54e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
IMFCPDME_00909	3.54e-195	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IMFCPDME_00910	5.98e-100	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
IMFCPDME_00911	1.98e-198	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IMFCPDME_00912	1.61e-292	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMFCPDME_00913	2.65e-217	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00914	1.41e-164	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IMFCPDME_00915	9.56e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IMFCPDME_00916	1.17e-176	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IMFCPDME_00917	1.9e-145	-	-	-	T	-	-	-	Xre family transcriptional regulator
IMFCPDME_00918	2.6e-142	yodC	-	-	C	-	-	-	nitroreductase
IMFCPDME_00919	1.65e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IMFCPDME_00920	7.66e-52	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	nuclease activity
IMFCPDME_00921	2.97e-41	XK27_10490	-	-	-	-	-	-	-
IMFCPDME_00922	1.99e-199	yvgN	-	-	C	-	-	-	reductase
IMFCPDME_00923	7.02e-268	-	-	-	S	-	-	-	Tetratricopeptide repeat
IMFCPDME_00924	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
IMFCPDME_00925	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
IMFCPDME_00926	2.58e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IMFCPDME_00927	4.24e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMFCPDME_00928	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
IMFCPDME_00929	2.83e-283	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMFCPDME_00930	2.23e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IMFCPDME_00931	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	COG0366 Glycosidases
IMFCPDME_00932	2.35e-287	vncS	2.7.13.3	-	T	ko:K10819	-	ko00000,ko01000	Histidine kinase
IMFCPDME_00933	1.06e-149	vncR	-	-	K	-	-	-	Response regulator receiver domain protein
IMFCPDME_00934	9.21e-304	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
IMFCPDME_00935	2.49e-140	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_00936	5.48e-267	vex1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
IMFCPDME_00937	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
IMFCPDME_00939	2.85e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	glycerol dehydrogenase
IMFCPDME_00940	1.67e-226	XK27_10475	-	-	S	-	-	-	oxidoreductase
IMFCPDME_00941	1.65e-76	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	dihydroxyacetone kinase, phosphotransfer subunit
IMFCPDME_00942	4.91e-124	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
IMFCPDME_00943	9.69e-227	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
IMFCPDME_00944	4.06e-286	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_00945	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
IMFCPDME_00946	2.16e-45	-	-	-	S	-	-	-	Immunity protein 41
IMFCPDME_00947	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IMFCPDME_00948	1.39e-12	-	-	-	S	-	-	-	Enterocin A Immunity
IMFCPDME_00949	5.91e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
IMFCPDME_00950	3.48e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IMFCPDME_00951	2.2e-149	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IMFCPDME_00952	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
IMFCPDME_00954	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00955	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
IMFCPDME_00956	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00957	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00958	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00959	4.01e-94	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
IMFCPDME_00960	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
IMFCPDME_00961	0.0	tcdB	-	-	S	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	dextransucrase activity
IMFCPDME_00962	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00963	2.73e-133	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMFCPDME_00964	4.13e-200	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMFCPDME_00965	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
IMFCPDME_00966	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00967	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00968	0.0	-	-	-	S	-	-	-	dextransucrase activity
IMFCPDME_00970	2.02e-169	-	-	-	S	-	-	-	CAAX protease self-immunity
IMFCPDME_00971	2.1e-306	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
IMFCPDME_00972	5.31e-90	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IMFCPDME_00973	1.37e-128	maa	2.3.1.79	-	GK	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
IMFCPDME_00974	7.48e-184	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
IMFCPDME_00975	0.0	-	3.5.1.28	-	M	ko:K01448,ko:K13733,ko:K20276	ko01503,ko02024,ko05100,map01503,map02024,map05100	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	domain protein
IMFCPDME_00976	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
IMFCPDME_00977	3.69e-141	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IMFCPDME_00978	1.38e-28	-	-	-	U	-	-	-	LPXTG cell wall anchor motif
IMFCPDME_00980	1.59e-17	-	-	-	S	-	-	-	Accessory secretory protein Sec, Asp5
IMFCPDME_00981	8.08e-16	-	-	-	S	-	-	-	Accessory secretory protein Sec Asp4
IMFCPDME_00982	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IMFCPDME_00983	4.44e-89	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
IMFCPDME_00984	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
IMFCPDME_00985	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
IMFCPDME_00986	8.5e-208	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
IMFCPDME_00987	5.76e-307	-	-	-	M	-	-	-	family 8
IMFCPDME_00988	0.0	-	-	-	M	-	-	-	cog cog1442
IMFCPDME_00989	3.89e-214	cpsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
IMFCPDME_00990	1.36e-300	-	-	-	M	-	-	-	Glycosyltransferase, family 8
IMFCPDME_00991	6.5e-235	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IMFCPDME_00992	2.87e-248	-	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IMFCPDME_00993	1.7e-312	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IMFCPDME_00994	2.72e-304	-	-	-	M	-	-	-	Glycosyltransferase, family 8
IMFCPDME_00995	2.51e-203	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	acetyltransferase'
IMFCPDME_00996	0.0	-	-	-	M	-	-	-	family 8
IMFCPDME_00997	6.08e-202	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	acetyltransferase'
IMFCPDME_01000	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
IMFCPDME_01001	3.3e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IMFCPDME_01002	0.0	-	-	-	GM	-	-	-	domain, Protein
IMFCPDME_01003	0.0	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	signal peptide protein, YSIRK family
IMFCPDME_01004	0.0	-	-	-	M	-	-	-	Pilin isopeptide linkage domain protein
IMFCPDME_01005	0.0	-	-	-	M	-	-	-	Pilin isopeptide linkage domain protein
IMFCPDME_01006	7.24e-234	XK27_10075	-	-	S	-	-	-	abc transporter atp-binding protein
IMFCPDME_01007	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_01008	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_01009	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
IMFCPDME_01011	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
IMFCPDME_01012	8.59e-127	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
IMFCPDME_01013	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IMFCPDME_01014	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IMFCPDME_01015	9.81e-231	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	glucose-1-phosphate adenylyltransferase
IMFCPDME_01016	1.47e-249	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMFCPDME_01017	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMFCPDME_01018	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
IMFCPDME_01019	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IMFCPDME_01020	1.92e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IMFCPDME_01021	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IMFCPDME_01022	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMFCPDME_01025	1.9e-146	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMFCPDME_01026	2.53e-221	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IMFCPDME_01027	1.72e-151	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Membrane
IMFCPDME_01028	1.98e-140	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
IMFCPDME_01029	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IMFCPDME_01030	1.14e-176	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IMFCPDME_01031	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMFCPDME_01032	4.08e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMFCPDME_01033	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMFCPDME_01034	1.37e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
IMFCPDME_01035	4.34e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IMFCPDME_01036	6.83e-275	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IMFCPDME_01037	1.18e-187	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
IMFCPDME_01038	2.22e-188	-	-	-	S	-	-	-	overlaps another CDS with the same product name
IMFCPDME_01039	8.13e-82	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
IMFCPDME_01040	1.44e-159	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01041	3.86e-167	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_01042	4.08e-218	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMFCPDME_01043	1.15e-257	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMFCPDME_01044	4.05e-213	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01045	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01046	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IMFCPDME_01047	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IMFCPDME_01048	5.01e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IMFCPDME_01049	8.95e-221	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IMFCPDME_01050	5.67e-196	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMFCPDME_01051	2.4e-153	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
IMFCPDME_01052	2.26e-129	yjbK	-	-	S	-	-	-	Adenylate cyclase
IMFCPDME_01053	2.37e-224	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMFCPDME_01054	1.34e-257	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IMFCPDME_01055	1.25e-78	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IMFCPDME_01056	3.68e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IMFCPDME_01057	5.88e-163	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
IMFCPDME_01058	2.67e-153	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IMFCPDME_01059	9.18e-207	-	-	-	-	-	-	-	-
IMFCPDME_01060	1.86e-38	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_01061	2.08e-198	-	-	-	M	-	-	-	Glycosyl transferase family 2
IMFCPDME_01062	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
IMFCPDME_01063	1.29e-234	rgpEc	-	GT2	M	ko:K12998	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
IMFCPDME_01064	1.92e-283	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IMFCPDME_01065	4.1e-182	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
IMFCPDME_01066	1.96e-225	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IMFCPDME_01067	1.35e-268	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
IMFCPDME_01068	2.34e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IMFCPDME_01069	7.94e-220	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
IMFCPDME_01070	1.01e-73	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
IMFCPDME_01071	2.49e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IMFCPDME_01072	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IMFCPDME_01073	4.88e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IMFCPDME_01074	8.61e-28	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IMFCPDME_01075	2.45e-176	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IMFCPDME_01076	6.77e-270	arcT	-	-	E	-	-	-	Aminotransferase
IMFCPDME_01077	6.55e-179	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IMFCPDME_01078	7.65e-183	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
IMFCPDME_01079	7.49e-110	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
IMFCPDME_01080	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IMFCPDME_01082	6.48e-216	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
IMFCPDME_01083	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMFCPDME_01084	3.54e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_01085	5.23e-25	XK27_00735	-	-	-	-	-	-	-
IMFCPDME_01086	3.8e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMFCPDME_01087	9.86e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IMFCPDME_01088	5.85e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IMFCPDME_01089	4.89e-09	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
IMFCPDME_01090	1.35e-80	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
IMFCPDME_01091	3.93e-78	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
IMFCPDME_01093	1.55e-195	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
IMFCPDME_01095	4.14e-146	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
IMFCPDME_01096	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMFCPDME_01097	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMFCPDME_01098	1.25e-127	-	-	-	S	-	-	-	IA, variant 1
IMFCPDME_01099	5.34e-150	lrgB	-	-	M	-	-	-	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IMFCPDME_01100	1.69e-73	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
IMFCPDME_01101	7.61e-07	-	-	-	S	-	-	-	AAA domain
IMFCPDME_01102	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IMFCPDME_01103	7.44e-218	-	-	-	S	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
IMFCPDME_01104	1.96e-138	rimL	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IMFCPDME_01105	2.56e-140	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMFCPDME_01106	1.38e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IMFCPDME_01108	1.7e-190	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
IMFCPDME_01109	1.83e-198	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IMFCPDME_01110	1.47e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IMFCPDME_01111	5.77e-189	icaB	-	-	G	-	-	-	deacetylase
IMFCPDME_01112	4.19e-263	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IMFCPDME_01113	5.77e-161	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMFCPDME_01114	2e-283	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMFCPDME_01115	1.17e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMFCPDME_01116	6.75e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
IMFCPDME_01117	4.73e-184	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IMFCPDME_01118	0.0	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IMFCPDME_01120	1.32e-291	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IMFCPDME_01121	6.59e-171	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
IMFCPDME_01122	0.0	-	-	-	M	-	-	-	GBS Bsp-like repeat
IMFCPDME_01124	2.98e-12	-	-	-	-	-	-	-	-
IMFCPDME_01125	2.34e-160	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IMFCPDME_01126	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IMFCPDME_01127	5.43e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IMFCPDME_01128	2.58e-73	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IMFCPDME_01129	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMFCPDME_01130	1.07e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IMFCPDME_01131	6.79e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
IMFCPDME_01133	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMFCPDME_01135	1.78e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IMFCPDME_01136	1.62e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
IMFCPDME_01137	5.89e-296	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IMFCPDME_01138	1.77e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMFCPDME_01139	8.92e-87	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IMFCPDME_01140	3.05e-280	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMFCPDME_01141	2.3e-135	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
IMFCPDME_01142	2.09e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMFCPDME_01143	1.5e-203	-	-	-	GK	-	-	-	ROK family
IMFCPDME_01144	2.36e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
IMFCPDME_01145	4.79e-196	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
IMFCPDME_01146	2.14e-259	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
IMFCPDME_01147	3.07e-167	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
IMFCPDME_01148	4.03e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
IMFCPDME_01149	1.08e-269	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IMFCPDME_01150	6.53e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IMFCPDME_01151	3.96e-107	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMFCPDME_01152	3.53e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMFCPDME_01153	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IMFCPDME_01154	5.02e-186	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMFCPDME_01155	4.02e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
IMFCPDME_01156	0.0	ydaO	-	-	E	-	-	-	amino acid
IMFCPDME_01157	1.93e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IMFCPDME_01158	3.17e-50	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IMFCPDME_01159	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IMFCPDME_01161	5.9e-255	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IMFCPDME_01162	2.67e-166	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
IMFCPDME_01163	5.9e-250	-	-	-	O	-	-	-	protein import
IMFCPDME_01164	5.79e-214	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
IMFCPDME_01165	3.71e-15	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IMFCPDME_01166	2.9e-254	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMFCPDME_01168	8.48e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IMFCPDME_01169	5.55e-94	-	-	-	S	-	-	-	QueT transporter
IMFCPDME_01171	7.12e-229	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
IMFCPDME_01173	2.23e-236	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IMFCPDME_01174	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMFCPDME_01175	1.4e-110	ccl	-	-	S	-	-	-	cog cog4708
IMFCPDME_01176	3.3e-210	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IMFCPDME_01177	4.94e-212	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IMFCPDME_01178	7.45e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IMFCPDME_01179	1.44e-127	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
IMFCPDME_01180	1.34e-295	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMFCPDME_01181	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IMFCPDME_01182	2.22e-140	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IMFCPDME_01183	5.9e-182	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IMFCPDME_01184	1.79e-209	nodB3	-	-	G	-	-	-	deacetylase
IMFCPDME_01185	1.5e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
IMFCPDME_01186	3.52e-57	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IMFCPDME_01187	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IMFCPDME_01188	1.1e-202	corA	-	-	P	-	-	-	CorA-like protein
IMFCPDME_01189	1.51e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
IMFCPDME_01190	3.76e-128	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
IMFCPDME_01191	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMFCPDME_01192	8.67e-151	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
IMFCPDME_01193	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IMFCPDME_01197	2.71e-199	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IMFCPDME_01198	4.44e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_01199	3.24e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01200	2.46e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01201	4.39e-244	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IMFCPDME_01202	2.72e-42	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
IMFCPDME_01203	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IMFCPDME_01204	3.52e-96	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
IMFCPDME_01205	7.72e-207	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
IMFCPDME_01206	1.01e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IMFCPDME_01207	1.22e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IMFCPDME_01208	6.23e-128	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
IMFCPDME_01209	2.66e-171	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IMFCPDME_01210	3.01e-228	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMFCPDME_01211	7.09e-136	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
IMFCPDME_01212	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMFCPDME_01213	1.03e-55	-	4.2.99.21	-	E	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Chorismate mutase type II
IMFCPDME_01214	1.33e-77	-	-	-	-	-	-	-	-
IMFCPDME_01215	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IMFCPDME_01216	3.94e-55	-	-	-	-	-	-	-	-
IMFCPDME_01217	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMFCPDME_01219	6.76e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01220	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01221	6.04e-169	-	-	-	K	-	-	-	transcriptional regulator, MerR family
IMFCPDME_01222	5.11e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IMFCPDME_01223	5.18e-76	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
IMFCPDME_01224	4.76e-84	XK27_02560	-	-	S	-	-	-	cog cog2151
IMFCPDME_01225	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
IMFCPDME_01226	1.03e-283	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
IMFCPDME_01228	8.79e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IMFCPDME_01229	2.95e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
IMFCPDME_01230	1.55e-225	XK27_05910	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IMFCPDME_01231	9.7e-168	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01232	3.56e-94	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IMFCPDME_01236	1.98e-133	-	-	-	-	-	-	-	-
IMFCPDME_01238	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
IMFCPDME_01240	3.37e-251	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IMFCPDME_01241	1.5e-177	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
IMFCPDME_01242	3.42e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IMFCPDME_01243	2.86e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IMFCPDME_01244	6.44e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMFCPDME_01245	4.57e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IMFCPDME_01246	3.11e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IMFCPDME_01247	4.52e-128	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IMFCPDME_01248	5.35e-196	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IMFCPDME_01249	2.32e-82	-	-	-	-	-	-	-	-
IMFCPDME_01250	1.74e-280	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMFCPDME_01251	2.78e-73	-	-	-	-	-	-	-	-
IMFCPDME_01252	4.76e-53	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
IMFCPDME_01253	0.0	celR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IMFCPDME_01254	4.78e-62	celB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IMFCPDME_01255	1.09e-42	-	-	-	S	ko:K15383	-	ko00000,ko02000	PQ loop repeat
IMFCPDME_01256	0.0	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IMFCPDME_01258	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMFCPDME_01259	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IMFCPDME_01260	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMFCPDME_01261	1.12e-76	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
IMFCPDME_01262	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IMFCPDME_01263	1.5e-130	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
IMFCPDME_01264	2.12e-180	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IMFCPDME_01265	6.15e-302	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IMFCPDME_01266	6.2e-98	XK27_03180	-	-	T	-	-	-	universal stress protein
IMFCPDME_01268	1.21e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMFCPDME_01270	9.57e-303	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
IMFCPDME_01271	3.03e-184	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_01272	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
IMFCPDME_01274	3.01e-125	mraW1	-	-	J	-	-	-	(SAM)-dependent
IMFCPDME_01275	3.57e-235	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
IMFCPDME_01276	4.34e-240	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IMFCPDME_01277	1.53e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMFCPDME_01278	2.94e-134	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IMFCPDME_01279	1.17e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IMFCPDME_01280	7.33e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
IMFCPDME_01281	3.24e-168	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_01282	1.4e-208	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01283	2.32e-196	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
IMFCPDME_01285	4.17e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMFCPDME_01286	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
IMFCPDME_01288	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IMFCPDME_01289	1.4e-189	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
IMFCPDME_01290	4.67e-98	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMFCPDME_01292	3.22e-218	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
IMFCPDME_01293	5.62e-181	cppA	-	-	E	-	-	-	CppA N-terminal
IMFCPDME_01294	3.8e-132	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IMFCPDME_01295	7.88e-210	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IMFCPDME_01296	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IMFCPDME_01302	6.95e-17	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
IMFCPDME_01305	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01306	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01308	6.65e-121	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
IMFCPDME_01309	2.25e-285	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IMFCPDME_01310	8.19e-113	yutD	-	-	J	-	-	-	protein conserved in bacteria
IMFCPDME_01311	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IMFCPDME_01313	5.13e-217	-	-	-	T	-	-	-	GHKL domain
IMFCPDME_01314	1.17e-163	lytTr	-	-	KT	-	-	-	COG3279 Response regulator of the LytR AlgR family
IMFCPDME_01315	3.74e-160	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IMFCPDME_01316	6.13e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IMFCPDME_01317	4.56e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IMFCPDME_01318	3.15e-233	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMFCPDME_01319	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
IMFCPDME_01320	5.32e-60	ftsL	-	-	D	-	-	-	cell division protein FtsL
IMFCPDME_01321	2.67e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IMFCPDME_01324	1.67e-91	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
IMFCPDME_01325	3.81e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IMFCPDME_01326	1.22e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMFCPDME_01327	4.99e-182	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMFCPDME_01328	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IMFCPDME_01329	5.01e-170	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01330	1.48e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IMFCPDME_01331	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IMFCPDME_01332	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IMFCPDME_01333	1.29e-314	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_01334	8.96e-309	dcuS	2.7.13.3	-	T	ko:K02476,ko:K07701,ko:K07706,ko:K11614	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IMFCPDME_01335	8.5e-15	-	-	-	-	-	-	-	-
IMFCPDME_01338	2.4e-186	-	-	-	V	ko:K21397	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
IMFCPDME_01340	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
IMFCPDME_01341	5.48e-143	-	-	-	S	-	-	-	membrane
IMFCPDME_01342	1.34e-98	XK27_02470	-	-	K	-	-	-	LytTr DNA-binding domain protein
IMFCPDME_01343	0.0	-	-	-	KT	-	-	-	response to antibiotic
IMFCPDME_01344	9.47e-167	yebC	-	-	M	-	-	-	Membrane
IMFCPDME_01345	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
IMFCPDME_01346	9.73e-223	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IMFCPDME_01348	4.07e-43	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IMFCPDME_01352	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMFCPDME_01353	1.61e-251	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMFCPDME_01354	3.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IMFCPDME_01355	9.04e-250	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMFCPDME_01356	1.67e-250	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMFCPDME_01357	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IMFCPDME_01359	1.03e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IMFCPDME_01360	2.37e-220	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
IMFCPDME_01361	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_01362	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IMFCPDME_01363	3.67e-227	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	Transcriptional regulator
IMFCPDME_01364	1.09e-95	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMFCPDME_01365	2.12e-79	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
IMFCPDME_01366	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMFCPDME_01367	3.59e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IMFCPDME_01368	5.88e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
IMFCPDME_01369	2.65e-38	blpT	-	-	-	-	-	-	-
IMFCPDME_01372	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMFCPDME_01373	1.41e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
IMFCPDME_01374	8.39e-159	XK27_01040	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IMFCPDME_01376	4.1e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMFCPDME_01377	4.18e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMFCPDME_01378	6.54e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IMFCPDME_01379	4.05e-53	XK27_05745	-	-	-	-	-	-	-
IMFCPDME_01380	5.55e-292	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
IMFCPDME_01382	2.62e-09	-	-	-	-	-	-	-	-
IMFCPDME_01383	4.59e-49	-	-	-	-	-	-	-	-
IMFCPDME_01384	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMFCPDME_01385	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IMFCPDME_01386	2.79e-120	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
IMFCPDME_01387	1.18e-20	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IMFCPDME_01388	3.06e-198	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMFCPDME_01389	2.61e-148	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IMFCPDME_01390	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IMFCPDME_01391	2.69e-61	-	-	-	S	-	-	-	branched-chain amino acid
IMFCPDME_01392	4.18e-147	XK27_12120	-	-	E	-	-	-	AzlC protein
IMFCPDME_01393	2.72e-237	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMFCPDME_01394	2.98e-94	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IMFCPDME_01395	4.07e-147	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
IMFCPDME_01396	4.54e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IMFCPDME_01397	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMFCPDME_01398	4.35e-150	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
IMFCPDME_01399	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IMFCPDME_01400	4e-82	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
IMFCPDME_01401	4.38e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IMFCPDME_01402	3.32e-283	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IMFCPDME_01404	1.41e-239	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IMFCPDME_01405	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMFCPDME_01406	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IMFCPDME_01407	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMFCPDME_01408	7.91e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
IMFCPDME_01409	4.14e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
IMFCPDME_01410	1.62e-229	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
IMFCPDME_01411	6.44e-152	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IMFCPDME_01412	4.67e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IMFCPDME_01413	2.64e-209	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IMFCPDME_01415	1.02e-197	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IMFCPDME_01416	2.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMFCPDME_01417	1.16e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
IMFCPDME_01418	7.39e-98	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IMFCPDME_01419	5.36e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IMFCPDME_01420	1.75e-183	-	-	-	S	-	-	-	Macro domain protein
IMFCPDME_01421	3.68e-77	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
IMFCPDME_01422	2.89e-73	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
IMFCPDME_01423	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IMFCPDME_01424	3.08e-62	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
IMFCPDME_01425	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
IMFCPDME_01426	2.03e-130	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-quinone reductase (modulator of drug activity B)
IMFCPDME_01427	3.81e-135	-	-	-	K	-	-	-	Transcriptional regulator
IMFCPDME_01428	5.32e-201	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
IMFCPDME_01429	4.24e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMFCPDME_01430	9.69e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IMFCPDME_01431	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
IMFCPDME_01432	3.51e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IMFCPDME_01433	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
IMFCPDME_01434	4.22e-48	-	-	-	S	-	-	-	MORN repeat protein
IMFCPDME_01435	5.19e-103	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMFCPDME_01436	1.83e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMFCPDME_01437	9.92e-122	flaR	-	-	F	-	-	-	topology modulation protein
IMFCPDME_01439	6.76e-251	ltrA	-	-	S	-	-	-	Low temperature requirement protein
IMFCPDME_01440	5.96e-220	-	-	-	S	-	-	-	membrane
IMFCPDME_01441	1.07e-114	-	-	-	K	-	-	-	sequence-specific DNA binding
IMFCPDME_01442	3.95e-208	-	-	-	L	-	-	-	Replication initiation factor
IMFCPDME_01443	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
IMFCPDME_01444	1.75e-277	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMFCPDME_01446	5.94e-300	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
IMFCPDME_01447	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IMFCPDME_01448	9.75e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IMFCPDME_01449	9.82e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMFCPDME_01450	1.34e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IMFCPDME_01451	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IMFCPDME_01452	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IMFCPDME_01453	7.68e-20	-	-	-	-	-	-	-	-
IMFCPDME_01454	4.94e-114	-	-	-	K	-	-	-	acetyltransferase
IMFCPDME_01455	3.61e-149	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMFCPDME_01456	1.09e-154	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IMFCPDME_01457	1.46e-213	XK27_01785	-	-	S	-	-	-	cog cog1284
IMFCPDME_01458	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IMFCPDME_01460	1.79e-303	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IMFCPDME_01461	4.3e-311	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_01462	7.11e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IMFCPDME_01463	8.74e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IMFCPDME_01464	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IMFCPDME_01465	3.22e-73	-	-	-	-	-	-	-	-
IMFCPDME_01468	4.42e-58	-	-	-	-	-	-	-	-
IMFCPDME_01469	4.63e-235	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IMFCPDME_01470	1.51e-61	-	-	-	-	-	-	-	-
IMFCPDME_01471	6.63e-117	-	-	-	S	-	-	-	Plasmid replication protein
IMFCPDME_01472	2.37e-26	-	-	-	S	-	-	-	MerR HTH family regulatory protein
IMFCPDME_01473	4.79e-262	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IMFCPDME_01477	5.55e-149	XK27_06885	-	-	L	-	-	-	hydrolase
IMFCPDME_01478	1.24e-68	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
IMFCPDME_01479	6.02e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
IMFCPDME_01480	3.59e-145	-	-	-	S	-	-	-	Putative adhesin
IMFCPDME_01481	4.93e-260	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
IMFCPDME_01482	1.39e-124	XK27_06935	-	-	K	-	-	-	transcriptional regulator
IMFCPDME_01483	1.32e-71	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
IMFCPDME_01484	5.32e-13	-	-	-	-	-	-	-	-
IMFCPDME_01485	1.25e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMFCPDME_01486	6.16e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
IMFCPDME_01487	1.35e-314	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IMFCPDME_01488	1.77e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IMFCPDME_01489	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IMFCPDME_01490	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IMFCPDME_01491	6.35e-131	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IMFCPDME_01492	5.42e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IMFCPDME_01493	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IMFCPDME_01494	5.86e-127	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
IMFCPDME_01495	7.75e-100	lytE	-	-	M	-	-	-	LysM domain protein
IMFCPDME_01496	6.19e-170	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMFCPDME_01497	1.83e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMFCPDME_01498	1.06e-192	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMFCPDME_01499	2.68e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMFCPDME_01500	2.02e-167	-	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
IMFCPDME_01501	6.72e-303	ymfH	-	-	S	-	-	-	Peptidase M16
IMFCPDME_01502	1.69e-296	albE	-	-	S	-	-	-	Peptidase M16
IMFCPDME_01503	2.94e-75	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
IMFCPDME_01504	2.4e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMFCPDME_01505	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IMFCPDME_01506	1.93e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IMFCPDME_01507	3.8e-193	XK27_10395	-	-	S	-	-	-	membrane
IMFCPDME_01508	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
IMFCPDME_01509	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
IMFCPDME_01513	7.75e-154	yoaK	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IMFCPDME_01514	8.3e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMFCPDME_01515	1.01e-274	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IMFCPDME_01516	1.6e-172	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IMFCPDME_01517	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMFCPDME_01518	9.69e-254	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IMFCPDME_01519	1.4e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_01520	3.04e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IMFCPDME_01521	2.11e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IMFCPDME_01522	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMFCPDME_01523	7.62e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IMFCPDME_01524	3.9e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IMFCPDME_01525	1.36e-05	-	-	-	-	-	-	-	-
IMFCPDME_01526	6.7e-301	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
IMFCPDME_01527	2.33e-301	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IMFCPDME_01528	3.15e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMFCPDME_01529	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMFCPDME_01530	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01531	2.21e-190	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
IMFCPDME_01532	8.9e-36	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_01539	3.06e-261	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IMFCPDME_01540	1.45e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
IMFCPDME_01541	1.39e-88	-	-	-	-	-	-	-	-
IMFCPDME_01542	1.27e-291	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
IMFCPDME_01543	2.88e-95	-	-	-	-	-	-	-	-
IMFCPDME_01544	9.17e-100	-	-	-	K	-	-	-	transcriptional
IMFCPDME_01545	8.74e-139	-	-	-	S	-	-	-	Tetratricopeptide repeat
IMFCPDME_01547	5.75e-203	-	-	-	-	-	-	-	-
IMFCPDME_01549	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMFCPDME_01550	1.46e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IMFCPDME_01551	1.92e-46	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
IMFCPDME_01552	1.89e-95	-	-	-	K	-	-	-	Transcriptional regulator, marr family
IMFCPDME_01553	3.81e-123	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
IMFCPDME_01555	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase
IMFCPDME_01556	1.73e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	alkyl hydroperoxide reductase
IMFCPDME_01557	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IMFCPDME_01558	1.23e-233	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMFCPDME_01559	1.69e-107	-	-	-	S	-	-	-	Putative small multi-drug export protein
IMFCPDME_01560	9.88e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IMFCPDME_01561	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IMFCPDME_01562	1.74e-298	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IMFCPDME_01563	5.36e-292	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IMFCPDME_01564	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IMFCPDME_01565	3.4e-179	-	-	-	S	-	-	-	SseB protein N-terminal domain
IMFCPDME_01566	6.37e-144	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
IMFCPDME_01568	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IMFCPDME_01569	1.22e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMFCPDME_01571	1.75e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMFCPDME_01572	2e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IMFCPDME_01573	3.03e-197	yitS	-	-	S	-	-	-	DegV family
IMFCPDME_01575	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
IMFCPDME_01576	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMFCPDME_01577	7.39e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IMFCPDME_01578	1.34e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_01579	1.2e-120	-	-	-	H	-	-	-	Methyltransferase
IMFCPDME_01581	1.34e-132	cadD	-	-	P	-	-	-	cadmium resistance
IMFCPDME_01582	3.11e-73	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
IMFCPDME_01584	3.02e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
IMFCPDME_01585	9.78e-123	-	-	-	-	-	-	-	-
IMFCPDME_01586	5.05e-179	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	sortase, SrtB family
IMFCPDME_01587	1.49e-295	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
IMFCPDME_01588	7.18e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
IMFCPDME_01589	5.19e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IMFCPDME_01590	8.38e-169	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
IMFCPDME_01591	5.58e-178	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IMFCPDME_01592	5.77e-131	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Muramidase (Flagellum-specific)
IMFCPDME_01593	5.71e-238	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IMFCPDME_01594	2.44e-105	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMFCPDME_01595	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IMFCPDME_01597	6.04e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IMFCPDME_01598	6.12e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IMFCPDME_01599	1.01e-174	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
IMFCPDME_01600	1.68e-103	hmpT	-	-	S	-	-	-	cog cog4720
IMFCPDME_01602	9.6e-307	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IMFCPDME_01603	3.99e-181	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902 family
IMFCPDME_01604	7.74e-86	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
IMFCPDME_01605	8.96e-223	-	-	-	L	ko:K07482	-	ko00000	Integrase
IMFCPDME_01606	1.02e-56	exo	3.1.11.3	-	L	ko:K01143	-	ko00000,ko01000	Exonuclease
IMFCPDME_01608	2.65e-113	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
IMFCPDME_01609	2.37e-178	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IMFCPDME_01610	1.81e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IMFCPDME_01611	2.5e-101	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IMFCPDME_01612	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IMFCPDME_01613	3.55e-109	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
IMFCPDME_01614	2.38e-99	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IMFCPDME_01615	9.75e-110	XK27_02675	-	-	K	-	-	-	Acetyltransferase GNAT Family
IMFCPDME_01616	2.03e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IMFCPDME_01617	3.95e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IMFCPDME_01618	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IMFCPDME_01619	6.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IMFCPDME_01620	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMFCPDME_01621	5.55e-95	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IMFCPDME_01622	0.0	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
IMFCPDME_01623	2.24e-301	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMFCPDME_01624	5.97e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IMFCPDME_01625	3.16e-144	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IMFCPDME_01626	1.63e-244	XK27_00055	-	-	P	-	-	-	Major Facilitator
IMFCPDME_01627	3.52e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMFCPDME_01628	9.11e-127	-	-	-	V	-	-	-	VanZ like family
IMFCPDME_01629	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
IMFCPDME_01630	4.26e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IMFCPDME_01631	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMFCPDME_01632	1.75e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IMFCPDME_01634	7.31e-166	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IMFCPDME_01635	7.71e-243	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IMFCPDME_01636	1.65e-176	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IMFCPDME_01637	2.81e-297	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IMFCPDME_01638	2.82e-301	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMFCPDME_01639	2.2e-95	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IMFCPDME_01640	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IMFCPDME_01641	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IMFCPDME_01642	2.5e-205	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMFCPDME_01643	5.54e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMFCPDME_01644	1.55e-252	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMFCPDME_01645	3.94e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IMFCPDME_01646	1.43e-33	-	-	-	-	-	-	-	-
IMFCPDME_01647	4.5e-200	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMFCPDME_01648	2.41e-233	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMFCPDME_01649	2.39e-90	adcR	-	-	K	-	-	-	transcriptional
IMFCPDME_01650	3.43e-173	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IMFCPDME_01651	4.25e-164	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01652	3.86e-205	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IMFCPDME_01653	0.0	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_01654	3.37e-201	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
IMFCPDME_01655	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IMFCPDME_01656	3.8e-193	Z012_04635	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IMFCPDME_01657	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
IMFCPDME_01658	2.03e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IMFCPDME_01659	7.16e-64	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
IMFCPDME_01660	3.56e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMFCPDME_01661	5.24e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IMFCPDME_01662	5.21e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IMFCPDME_01663	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IMFCPDME_01664	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
IMFCPDME_01665	2.47e-182	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01666	6.35e-56	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMFCPDME_01667	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IMFCPDME_01669	1.71e-59	-	-	-	-	-	-	-	-
IMFCPDME_01670	2.12e-70	WQ51_06355	-	-	S	-	-	-	TM2 domain
IMFCPDME_01671	2.09e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IMFCPDME_01672	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IMFCPDME_01673	2.73e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IMFCPDME_01674	1.05e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
IMFCPDME_01675	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IMFCPDME_01676	3.06e-88	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
IMFCPDME_01677	2.3e-188	cof	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IMFCPDME_01678	2.04e-175	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
IMFCPDME_01679	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IMFCPDME_01680	1.46e-101	napB	-	-	K	-	-	-	transcriptional
IMFCPDME_01681	1.3e-306	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IMFCPDME_01682	1.83e-61	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IMFCPDME_01683	1.24e-197	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IMFCPDME_01684	4.84e-175	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IMFCPDME_01685	2.83e-99	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IMFCPDME_01686	3.6e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IMFCPDME_01687	2.38e-160	mta	-	-	K	ko:K21743	-	ko00000,ko03000	Transcriptional
IMFCPDME_01688	3.66e-153	-	-	-	V	-	-	-	abc transporter atp-binding protein
IMFCPDME_01689	4.97e-265	-	-	-	V	-	-	-	FtsX-like permease family
IMFCPDME_01690	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMFCPDME_01691	2.92e-193	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IMFCPDME_01692	5.35e-102	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
IMFCPDME_01693	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IMFCPDME_01694	1.53e-100	-	-	-	L	-	-	-	Transposase
IMFCPDME_01695	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IMFCPDME_01696	1.65e-139	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IMFCPDME_01697	1.78e-123	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IMFCPDME_01698	3.97e-66	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IMFCPDME_01699	2.62e-284	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IMFCPDME_01700	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IMFCPDME_01701	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
IMFCPDME_01702	4.8e-28	XK27_11680	-	-	-	-	-	-	-
IMFCPDME_01703	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IMFCPDME_01704	7.33e-115	-	-	-	K	-	-	-	histone acetyltransferase HPA2 and related acetyltransferases
IMFCPDME_01705	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMFCPDME_01706	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IMFCPDME_01707	1.07e-211	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMFCPDME_01708	5.51e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IMFCPDME_01709	1.27e-164	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMFCPDME_01710	6.25e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
IMFCPDME_01711	1.71e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IMFCPDME_01713	1.42e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IMFCPDME_01714	3.12e-117	-	-	-	K	-	-	-	transcriptional regulator
IMFCPDME_01715	2.31e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IMFCPDME_01716	2.92e-192	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IMFCPDME_01717	3.86e-235	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMFCPDME_01718	2.62e-126	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IMFCPDME_01719	1.81e-113	ykuL	-	-	S	-	-	-	CBS domain
IMFCPDME_01720	8.01e-173	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IMFCPDME_01721	4.56e-154	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMFCPDME_01722	1.11e-121	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMFCPDME_01723	1.23e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IMFCPDME_01724	9.94e-20	yidD	-	-	M	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IMFCPDME_01725	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
IMFCPDME_01726	9.42e-313	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
IMFCPDME_01727	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IMFCPDME_01728	1.36e-118	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMFCPDME_01729	4.6e-139	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
IMFCPDME_01730	8.82e-26	-	-	-	S	-	-	-	Bacteriophage lambda Kil protein
IMFCPDME_01732	5.83e-197	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IMFCPDME_01733	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IMFCPDME_01734	2.58e-71	yhaI	-	-	L	-	-	-	Membrane
IMFCPDME_01735	6.25e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
IMFCPDME_01736	2.16e-124	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
IMFCPDME_01737	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IMFCPDME_01738	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IMFCPDME_01739	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IMFCPDME_01740	1.36e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IMFCPDME_01741	1.06e-168	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IMFCPDME_01742	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IMFCPDME_01743	1.78e-206	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IMFCPDME_01744	1.18e-225	-	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biosynthesis protein CbiM
IMFCPDME_01745	2.77e-175	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
IMFCPDME_01746	7.71e-167	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IMFCPDME_01747	1.21e-185	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IMFCPDME_01748	7.28e-212	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IMFCPDME_01749	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IMFCPDME_01750	1.99e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMFCPDME_01751	1.27e-152	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IMFCPDME_01752	1.47e-267	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IMFCPDME_01753	4.66e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IMFCPDME_01754	2.46e-301	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
IMFCPDME_01755	2.05e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
IMFCPDME_01756	1.55e-116	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IMFCPDME_01757	2.3e-159	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCPDME_01758	0.0	covS	-	-	T	-	-	-	Histidine kinase
IMFCPDME_01759	1.01e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMFCPDME_01760	2.04e-273	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
IMFCPDME_01761	1.26e-212	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IMFCPDME_01762	5.05e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IMFCPDME_01763	6.09e-136	-	-	-	-	-	-	-	-
IMFCPDME_01764	2.4e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMFCPDME_01765	1.25e-80	manO	-	-	S	-	-	-	protein conserved in bacteria
IMFCPDME_01766	1.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
IMFCPDME_01767	4.8e-166	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
IMFCPDME_01768	1.39e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_01769	1.62e-87	manO	-	-	S	-	-	-	Protein conserved in bacteria
IMFCPDME_01770	8.01e-202	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
IMFCPDME_01771	2.07e-169	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
IMFCPDME_01772	7.02e-223	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IMFCPDME_01773	2.93e-178	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
IMFCPDME_01774	2.07e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IMFCPDME_01775	9.67e-316	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IMFCPDME_01776	2.1e-99	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IMFCPDME_01777	3.18e-118	XK27_05885	2.3.1.82	-	M	ko:K18816	-	br01600,ko00000,ko01000,ko01504	phosphinothricin N-acetyltransferase activity
IMFCPDME_01778	7.29e-271	brpA	-	-	K	-	-	-	Transcriptional
IMFCPDME_01779	1.75e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IMFCPDME_01780	1.37e-258	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IMFCPDME_01781	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
IMFCPDME_01782	1.66e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
IMFCPDME_01783	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMFCPDME_01784	5.68e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMFCPDME_01785	9.66e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IMFCPDME_01786	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMFCPDME_01787	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IMFCPDME_01788	0.0	pacL	-	-	P	-	-	-	cation transport ATPase
IMFCPDME_01789	3.41e-256	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IMFCPDME_01790	2.62e-283	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IMFCPDME_01791	0.0	-	3.2.1.26, 3.2.1.65	GH32	G	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IMFCPDME_01792	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
IMFCPDME_01793	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMFCPDME_01794	7.57e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IMFCPDME_01795	4.73e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IMFCPDME_01796	1.77e-61	ylbG	-	-	S	-	-	-	UPF0298 protein
IMFCPDME_01797	1.77e-270	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IMFCPDME_01798	1.65e-189	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IMFCPDME_01799	6.66e-184	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IMFCPDME_01800	2.68e-175	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IMFCPDME_01801	4.6e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IMFCPDME_01802	2.67e-144	XK27_04065	-	-	S	ko:K04767	-	ko00000	CBS domain
IMFCPDME_01803	4.93e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IMFCPDME_01804	2.23e-142	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IMFCPDME_01805	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMFCPDME_01806	1.91e-110	comFC	-	-	K	ko:K02242	-	ko00000,ko00002,ko02044	competence protein
IMFCPDME_01807	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMFCPDME_01810	1.16e-213	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IMFCPDME_01811	3.15e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
IMFCPDME_01812	1.99e-132	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IMFCPDME_01813	1.14e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IMFCPDME_01814	1.53e-313	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMFCPDME_01815	1.53e-244	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IMFCPDME_01816	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IMFCPDME_01817	5.69e-147	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
IMFCPDME_01818	9.63e-181	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
IMFCPDME_01819	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
IMFCPDME_01820	6.74e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMFCPDME_01821	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMFCPDME_01822	3.23e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
IMFCPDME_01823	1.84e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IMFCPDME_01824	2.27e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IMFCPDME_01825	4.3e-296	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IMFCPDME_01826	1.85e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IMFCPDME_01827	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IMFCPDME_01828	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IMFCPDME_01829	4.89e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMFCPDME_01830	4.63e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IMFCPDME_01831	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IMFCPDME_01832	6.36e-290	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IMFCPDME_01833	1.53e-162	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
IMFCPDME_01834	1.3e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IMFCPDME_01835	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IMFCPDME_01836	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMFCPDME_01837	3.4e-295	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IMFCPDME_01838	1.03e-06	-	-	-	-	-	-	-	-
IMFCPDME_01839	3.49e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IMFCPDME_01840	3.74e-284	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMFCPDME_01841	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IMFCPDME_01842	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IMFCPDME_01843	6.12e-123	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
IMFCPDME_01844	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IMFCPDME_01845	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IMFCPDME_01846	3.57e-173	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMFCPDME_01847	2.63e-82	WQ51_03320	-	-	S	-	-	-	cog cog4835
IMFCPDME_01848	6.12e-194	-	-	-	S	-	-	-	EDD domain protein, DegV family
IMFCPDME_01849	7.1e-176	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IMFCPDME_01850	3.32e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IMFCPDME_01851	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_01852	1.76e-29	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IMFCPDME_01853	1.21e-166	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
IMFCPDME_01854	1.08e-270	nadR	-	-	H	-	-	-	adenylyltransferase
IMFCPDME_01855	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IMFCPDME_01856	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IMFCPDME_01857	2.73e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IMFCPDME_01858	6.75e-96	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IMFCPDME_01859	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_01860	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IMFCPDME_01861	7.78e-145	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IMFCPDME_01862	5.29e-145	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
IMFCPDME_01863	3.02e-153	dltr	-	-	T	-	-	-	response regulator
IMFCPDME_01864	2.03e-272	sptS	-	-	T	-	-	-	Histidine kinase
IMFCPDME_01865	2.78e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IMFCPDME_01866	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IMFCPDME_01867	4.92e-207	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
IMFCPDME_01868	2.72e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IMFCPDME_01869	2.36e-224	sip	-	-	M	-	-	-	LysM domain protein
IMFCPDME_01870	2.44e-244	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IMFCPDME_01875	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMFCPDME_01876	5.12e-207	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IMFCPDME_01877	3.03e-215	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
IMFCPDME_01878	2.87e-134	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
IMFCPDME_01879	0.0	-	-	-	S	-	-	-	Glucan-binding protein C
IMFCPDME_01880	2.42e-205	-	-	-	S	-	-	-	CHAP domain
IMFCPDME_01881	1.88e-28	-	-	-	L	ko:K07497	-	ko00000	overlaps another CDS with the same product name
IMFCPDME_01882	6.21e-31	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IMFCPDME_01883	1.34e-43	-	-	-	L	-	-	-	transposition
IMFCPDME_01884	8.04e-230	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IMFCPDME_01885	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IMFCPDME_01886	2.91e-276	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IMFCPDME_01887	5.91e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
IMFCPDME_01888	2.27e-237	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
IMFCPDME_01889	1.09e-110	XK27_03390	-	-	S	-	-	-	LURP-one-related
IMFCPDME_01890	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMFCPDME_01893	4.66e-93	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
IMFCPDME_01894	1.02e-78	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IMFCPDME_01896	1.31e-252	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
IMFCPDME_01897	1.69e-22	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMFCPDME_01898	4.26e-158	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IMFCPDME_01899	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMFCPDME_01900	8.62e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMFCPDME_01901	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMFCPDME_01902	3.17e-202	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMFCPDME_01903	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMFCPDME_01904	1.24e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IMFCPDME_01905	3.93e-275	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IMFCPDME_01906	3.2e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMFCPDME_01907	7.68e-174	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IMFCPDME_01908	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate