ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HOCMNKEB_00017 1.36e-179 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HOCMNKEB_00018 1.34e-115 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HOCMNKEB_00019 2.74e-179 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
HOCMNKEB_00020 2.75e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOCMNKEB_00021 1.06e-278 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HOCMNKEB_00022 5.05e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HOCMNKEB_00023 1.28e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOCMNKEB_00024 1.93e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOCMNKEB_00025 1.5e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HOCMNKEB_00026 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOCMNKEB_00027 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOCMNKEB_00028 4.91e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HOCMNKEB_00029 6.85e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOCMNKEB_00030 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HOCMNKEB_00031 2.22e-34 WQ51_00785 - - - - - - -
HOCMNKEB_00032 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HOCMNKEB_00033 4.85e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HOCMNKEB_00034 8.04e-158 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HOCMNKEB_00035 2e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOCMNKEB_00036 1.24e-258 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOCMNKEB_00037 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOCMNKEB_00038 1.92e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HOCMNKEB_00039 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
HOCMNKEB_00040 6.06e-223 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HOCMNKEB_00041 6.18e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOCMNKEB_00042 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOCMNKEB_00043 1.4e-196 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HOCMNKEB_00044 0.0 msrR - - K - - - Transcriptional regulator
HOCMNKEB_00045 1.18e-107 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
HOCMNKEB_00046 2.09e-63 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
HOCMNKEB_00047 6.36e-256 - - - I - - - acyl-CoA dehydrogenase
HOCMNKEB_00048 5.21e-126 mip - - S - - - hydroperoxide reductase activity
HOCMNKEB_00049 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOCMNKEB_00050 1.23e-134 - - - - - - - -
HOCMNKEB_00051 4.3e-44 - - - K - - - Cro/C1-type HTH DNA-binding domain
HOCMNKEB_00052 2.66e-58 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
HOCMNKEB_00053 1.02e-32 - - - E - - - GDSL-like Lipase/Acylhydrolase
HOCMNKEB_00054 3.23e-124 - - - - - - - -
HOCMNKEB_00055 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HOCMNKEB_00056 6.55e-221 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOCMNKEB_00057 8.44e-71 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOCMNKEB_00058 1.68e-233 - - - S - - - CRISPR-associated protein Csn2 subfamily St
HOCMNKEB_00059 1.89e-188 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
HOCMNKEB_00060 1.14e-199 XK27_03015 - - S ko:K07089 - ko00000 permease
HOCMNKEB_00062 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
HOCMNKEB_00063 1.45e-55 WQ51_05770 - - KT - - - PspC domain
HOCMNKEB_00064 3.49e-219 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOCMNKEB_00065 1.51e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOCMNKEB_00066 1.14e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HOCMNKEB_00067 1.66e-91 ytxH - - S - - - General stress protein
HOCMNKEB_00069 1.23e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HOCMNKEB_00070 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HOCMNKEB_00071 3.62e-60 - - - S - - - CHY zinc finger
HOCMNKEB_00072 2.67e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
HOCMNKEB_00074 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
HOCMNKEB_00075 4.49e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HOCMNKEB_00076 3.6e-19 - - - - - - - -
HOCMNKEB_00077 1.39e-264 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HOCMNKEB_00078 8.02e-285 - - - L - - - DNA mismatch repair enzyme MutH
HOCMNKEB_00079 5.59e-40 - - - S - - - SIR2-like domain
HOCMNKEB_00080 3.48e-211 - - - S - - - SIR2-like domain
HOCMNKEB_00081 8.74e-209 - - - S ko:K06915 - ko00000 Domain of unknown function DUF87
HOCMNKEB_00084 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HOCMNKEB_00085 5.37e-20 - - - M - - - LysM domain
HOCMNKEB_00086 4.06e-75 - - - M - - - LysM domain
HOCMNKEB_00087 7.92e-29 - - - - - - - -
HOCMNKEB_00088 7.07e-219 - - - S ko:K07025 - ko00000 hydrolase
HOCMNKEB_00089 2.94e-149 pgm - - G - - - Phosphoglycerate mutase
HOCMNKEB_00090 2.49e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOCMNKEB_00091 2.83e-196 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
HOCMNKEB_00092 3.99e-36 - - - P - - - Hemerythrin HHE cation binding domain protein
HOCMNKEB_00093 1.4e-145 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCMNKEB_00094 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
HOCMNKEB_00095 6.03e-22 - - - S - - - Protein of unknown function (DUF2974)
HOCMNKEB_00096 5.04e-97 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCMNKEB_00097 1.54e-57 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCMNKEB_00098 0.0 - - - V - - - Type I restriction enzyme R protein N terminus (HSDR_N)
HOCMNKEB_00099 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HOCMNKEB_00100 7.41e-187 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
HOCMNKEB_00101 8.66e-186 - - - L - - - Protein of unknown function (DUF2813)
HOCMNKEB_00102 6.27e-113 - - - L - - - UvrD/REP helicase N-terminal domain
HOCMNKEB_00104 4.87e-45 - - - - - - - -
HOCMNKEB_00105 1.39e-241 higA - - K ko:K18831 - ko00000,ko02048,ko03000 Pfam:DUF955
HOCMNKEB_00106 1.25e-238 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HOCMNKEB_00107 7.6e-121 lemA - - S ko:K03744 - ko00000 LemA family
HOCMNKEB_00108 8.47e-190 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HOCMNKEB_00109 8.61e-97 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HOCMNKEB_00110 2.18e-73 - - - S - - - Domain of unknown function (DUF4430)
HOCMNKEB_00111 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HOCMNKEB_00112 2.71e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HOCMNKEB_00113 6.73e-145 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HOCMNKEB_00114 2.26e-204 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_00115 4.4e-63 - - - L - - - Transposase
HOCMNKEB_00116 1.4e-287 - - - V - - - D-alanyl-D-alanine carboxypeptidase
HOCMNKEB_00117 4.5e-150 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HOCMNKEB_00118 3.18e-118 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HOCMNKEB_00119 5.82e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HOCMNKEB_00120 7.8e-38 yqgQ - - S - - - protein conserved in bacteria
HOCMNKEB_00121 1.76e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HOCMNKEB_00122 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HOCMNKEB_00123 2.68e-12 - - - S - - - Protein of unknown function (DUF3165)
HOCMNKEB_00124 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOCMNKEB_00125 3.84e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOCMNKEB_00126 2.37e-236 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HOCMNKEB_00127 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HOCMNKEB_00128 2.64e-303 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOCMNKEB_00129 9.77e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOCMNKEB_00130 1.79e-125 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
HOCMNKEB_00131 1.8e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
HOCMNKEB_00132 1.68e-184 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
HOCMNKEB_00133 2.95e-186 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
HOCMNKEB_00134 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOCMNKEB_00135 5.37e-41 - - - - - - - -
HOCMNKEB_00136 1.93e-12 - - - - - - - -
HOCMNKEB_00137 4.66e-296 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
HOCMNKEB_00138 1.39e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
HOCMNKEB_00139 5.61e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOCMNKEB_00140 2.51e-236 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
HOCMNKEB_00141 7.83e-197 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
HOCMNKEB_00142 5.3e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HOCMNKEB_00143 1.16e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HOCMNKEB_00144 5.57e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOCMNKEB_00145 3.18e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOCMNKEB_00146 1.2e-140 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOCMNKEB_00147 2.06e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOCMNKEB_00148 4.29e-228 - - - S - - - 37-kD nucleoid-associated bacterial protein
HOCMNKEB_00149 1.1e-128 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
HOCMNKEB_00150 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00151 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00152 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCMNKEB_00153 2.52e-302 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
HOCMNKEB_00154 4.98e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCMNKEB_00155 1.48e-309 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HOCMNKEB_00156 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
HOCMNKEB_00157 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
HOCMNKEB_00159 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOCMNKEB_00160 6.24e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
HOCMNKEB_00161 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HOCMNKEB_00162 1.58e-122 - - - S - - - ECF transporter, substrate-specific component
HOCMNKEB_00163 1.23e-119 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOCMNKEB_00164 3.82e-157 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
HOCMNKEB_00165 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HOCMNKEB_00166 4.04e-86 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCMNKEB_00167 1.67e-49 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HOCMNKEB_00168 6.62e-53 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HOCMNKEB_00169 1.82e-165 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HOCMNKEB_00170 1.98e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
HOCMNKEB_00171 1.22e-222 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HOCMNKEB_00172 2.17e-134 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
HOCMNKEB_00173 2.18e-32 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HOCMNKEB_00174 5.3e-33 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
HOCMNKEB_00175 3.95e-29 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HOCMNKEB_00176 3.37e-80 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HOCMNKEB_00177 3.25e-38 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HOCMNKEB_00178 1.8e-81 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HOCMNKEB_00179 3.68e-62 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HOCMNKEB_00180 3.33e-243 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HOCMNKEB_00181 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HOCMNKEB_00182 5.56e-246 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HOCMNKEB_00183 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HOCMNKEB_00184 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HOCMNKEB_00185 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HOCMNKEB_00186 3.8e-106 ypmB - - S - - - Protein conserved in bacteria
HOCMNKEB_00187 3.85e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HOCMNKEB_00188 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HOCMNKEB_00190 4.89e-48 - - - L - - - Transposase
HOCMNKEB_00191 1.84e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
HOCMNKEB_00192 1.07e-158 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HOCMNKEB_00193 3.49e-107 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HOCMNKEB_00194 1.06e-173 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HOCMNKEB_00195 4.7e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HOCMNKEB_00196 5.88e-24 - - - D - - - nuclear chromosome segregation
HOCMNKEB_00197 6.3e-175 yejC - - S - - - cyclic nucleotide-binding protein
HOCMNKEB_00198 2.08e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HOCMNKEB_00199 1.06e-232 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HOCMNKEB_00200 1.2e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HOCMNKEB_00201 2.48e-68 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HOCMNKEB_00202 3.03e-76 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HOCMNKEB_00203 2.63e-44 - - - K - - - Cold shock protein domain
HOCMNKEB_00204 3.71e-57 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
HOCMNKEB_00205 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
HOCMNKEB_00206 7.76e-133 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HOCMNKEB_00208 1.04e-10 - - - K - - - Transcriptional regulator
HOCMNKEB_00210 6.15e-117 - - - L - - - Replication initiation factor
HOCMNKEB_00211 2.55e-15 - - - S - - - Domain of unknown function (DUF3173)
HOCMNKEB_00212 3.53e-277 - - - L - - - Belongs to the 'phage' integrase family
HOCMNKEB_00213 1.02e-97 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HOCMNKEB_00214 1.8e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HOCMNKEB_00215 1.45e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HOCMNKEB_00216 1.03e-126 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
HOCMNKEB_00217 1.45e-76 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
HOCMNKEB_00218 1.1e-143 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HOCMNKEB_00219 1.13e-192 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HOCMNKEB_00220 5.25e-08 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HOCMNKEB_00221 3.02e-98 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
HOCMNKEB_00222 4.16e-142 XK27_10720 - - D - - - peptidase activity
HOCMNKEB_00223 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HOCMNKEB_00225 6.43e-219 yeiH - - S - - - Membrane
HOCMNKEB_00226 2.26e-154 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
HOCMNKEB_00227 1.85e-125 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_00228 2.18e-214 cpsY - - K - - - Transcriptional regulator
HOCMNKEB_00229 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOCMNKEB_00230 7.71e-77 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
HOCMNKEB_00231 3.92e-134 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00232 1.06e-145 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00233 1.11e-202 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HOCMNKEB_00234 8.13e-180 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCMNKEB_00235 2.18e-10 - - - - - - - -
HOCMNKEB_00236 3.53e-76 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HOCMNKEB_00237 1.76e-143 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HOCMNKEB_00239 1.94e-27 - - - - - - - -
HOCMNKEB_00240 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 Type III restriction
HOCMNKEB_00241 0.0 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
HOCMNKEB_00242 7.5e-77 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
HOCMNKEB_00243 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HOCMNKEB_00244 3.67e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
HOCMNKEB_00245 9e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOCMNKEB_00246 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOCMNKEB_00247 8e-113 niaX - - - ko:K16788 - ko00000,ko02000 -
HOCMNKEB_00248 1.3e-116 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HOCMNKEB_00249 2.14e-164 - - - K - - - DNA-binding helix-turn-helix protein
HOCMNKEB_00250 1.46e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOCMNKEB_00251 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOCMNKEB_00252 1.79e-215 - - - GK - - - ROK family
HOCMNKEB_00253 9.91e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HOCMNKEB_00254 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOCMNKEB_00255 2.32e-195 - - - S - - - TraX protein
HOCMNKEB_00256 2.93e-157 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCMNKEB_00257 0.0 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HOCMNKEB_00258 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HOCMNKEB_00259 2.83e-195 XK27_05470 - - E - - - Methionine synthase
HOCMNKEB_00260 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HOCMNKEB_00261 2.89e-49 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOCMNKEB_00262 8.3e-67 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
HOCMNKEB_00263 1.01e-24 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
HOCMNKEB_00264 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOCMNKEB_00267 0.000789 - - - S - - - Toxin-antitoxin system, toxin component, RelE family
HOCMNKEB_00268 2.1e-70 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
HOCMNKEB_00269 1.77e-200 - - - K - - - Transcriptional activator, Rgg GadR MutR family
HOCMNKEB_00272 5.16e-272 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
HOCMNKEB_00273 3.15e-175 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HOCMNKEB_00274 9.01e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HOCMNKEB_00275 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HOCMNKEB_00276 1.34e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HOCMNKEB_00277 1.52e-125 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00278 3.35e-144 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCMNKEB_00279 9.28e-15 - - - - - - - -
HOCMNKEB_00280 4.42e-136 - - - K - - - Transcriptional regulator, TetR family
HOCMNKEB_00281 1.06e-203 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HOCMNKEB_00282 4.79e-268 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HOCMNKEB_00283 2.78e-250 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
HOCMNKEB_00284 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HOCMNKEB_00285 7.99e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HOCMNKEB_00286 2.95e-104 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HOCMNKEB_00289 4.01e-186 - - - F - - - Phosphorylase superfamily
HOCMNKEB_00290 6.95e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
HOCMNKEB_00291 5.56e-09 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HOCMNKEB_00292 1.89e-23 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
HOCMNKEB_00293 8.97e-70 dinF - - V - - - Mate efflux family protein
HOCMNKEB_00295 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HOCMNKEB_00296 0.000908 - - - S - - - TraX protein
HOCMNKEB_00297 1.69e-116 - - - S - - - TraX protein
HOCMNKEB_00298 2.12e-125 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
HOCMNKEB_00299 5.05e-191 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HOCMNKEB_00300 1.28e-224 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOCMNKEB_00301 2.16e-102 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_00302 2.71e-65 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_00303 2.67e-46 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_00304 6.22e-207 - - - S - - - CHAP domain
HOCMNKEB_00305 1.65e-305 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HOCMNKEB_00306 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOCMNKEB_00307 1.03e-261 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOCMNKEB_00308 1.69e-181 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
HOCMNKEB_00309 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOCMNKEB_00310 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HOCMNKEB_00311 1.42e-267 - - - L - - - Belongs to the 'phage' integrase family
HOCMNKEB_00312 9.98e-19 - - - K - - - Transcriptional
HOCMNKEB_00313 4.54e-25 - - - - - - - -
HOCMNKEB_00318 1.1e-29 - - - - - - - -
HOCMNKEB_00319 2.02e-172 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
HOCMNKEB_00320 1.34e-69 - - - S - - - Virulence-associated protein E
HOCMNKEB_00321 6e-46 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HOCMNKEB_00322 7.94e-69 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HOCMNKEB_00323 1.47e-254 nlaXM 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 cytosine-specific methyltransferase
HOCMNKEB_00324 2.49e-211 - - - S - - - NgoFVII restriction endonuclease
HOCMNKEB_00326 1.2e-34 - - - - - - - -
HOCMNKEB_00327 3.19e-190 - - - V - - - Abi-like protein
HOCMNKEB_00329 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HOCMNKEB_00330 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HOCMNKEB_00331 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOCMNKEB_00332 1.06e-43 - - - S - - - Protein of unknown function (DUF3021)
HOCMNKEB_00333 2.17e-81 - - - KT - - - phosphorelay signal transduction system
HOCMNKEB_00335 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOCMNKEB_00337 4.38e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOCMNKEB_00338 1.89e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
HOCMNKEB_00339 2.06e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HOCMNKEB_00340 5.4e-253 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOCMNKEB_00341 1.27e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HOCMNKEB_00342 7.21e-143 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 maintenance of DNA repeat elements
HOCMNKEB_00343 3.79e-92 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 maintenance of DNA repeat elements
HOCMNKEB_00344 2.91e-72 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOCMNKEB_00345 4.48e-173 - - - S - - - Pfam:DUF2276
HOCMNKEB_00346 4.52e-131 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
HOCMNKEB_00347 2.57e-50 csm2 - - L ko:K19138 - ko00000,ko02048 Csm2 Type III-A
HOCMNKEB_00348 4.46e-148 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
HOCMNKEB_00349 2.45e-214 csm4 - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
HOCMNKEB_00350 6.42e-262 csm5 - - L ko:K19140 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm5 family
HOCMNKEB_00351 7.98e-18 - - - S - - - Psort location Cytoplasmic, score
HOCMNKEB_00352 3.63e-94 - - - S - - - Psort location Cytoplasmic, score
HOCMNKEB_00353 8.35e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HOCMNKEB_00354 4.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOCMNKEB_00355 3.66e-11 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 amidase activity
HOCMNKEB_00356 3.14e-63 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HOCMNKEB_00357 0.0 dtpT - - E ko:K03305 - ko00000 transporter
HOCMNKEB_00358 3.65e-134 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HOCMNKEB_00359 1.06e-170 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HOCMNKEB_00360 2.39e-86 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00361 1.07e-09 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_00362 4.78e-142 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_00363 1.56e-45 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
HOCMNKEB_00364 4.64e-135 yfiF3 - - K - - - sequence-specific DNA binding
HOCMNKEB_00365 6.01e-307 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_00366 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOCMNKEB_00367 7.07e-307 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
HOCMNKEB_00368 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HOCMNKEB_00369 2.95e-307 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
HOCMNKEB_00370 6.69e-72 - - - Q - - - phosphatase activity
HOCMNKEB_00371 5.48e-79 - - - S - - - haloacid dehalogenase-like hydrolase
HOCMNKEB_00372 1.48e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOCMNKEB_00373 3.31e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
HOCMNKEB_00374 1.48e-195 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
HOCMNKEB_00375 5.19e-31 XK27_04775 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
HOCMNKEB_00376 2.83e-193 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOCMNKEB_00377 5.2e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HOCMNKEB_00378 7.52e-95 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HOCMNKEB_00379 1.99e-58 yktA - - S - - - Belongs to the UPF0223 family
HOCMNKEB_00380 8.38e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HOCMNKEB_00381 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HOCMNKEB_00382 1.19e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
HOCMNKEB_00383 6.58e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HOCMNKEB_00384 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
HOCMNKEB_00385 3.05e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOCMNKEB_00386 1.24e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOCMNKEB_00387 1.1e-147 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HOCMNKEB_00388 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HOCMNKEB_00389 7.63e-249 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HOCMNKEB_00390 2.63e-240 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HOCMNKEB_00393 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOCMNKEB_00394 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
HOCMNKEB_00396 4.79e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
HOCMNKEB_00397 1.83e-156 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOCMNKEB_00398 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HOCMNKEB_00399 2.59e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
HOCMNKEB_00400 8.71e-200 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HOCMNKEB_00401 1.13e-230 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
HOCMNKEB_00402 3.52e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00403 9.01e-214 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCMNKEB_00404 5.47e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCMNKEB_00405 1.18e-165 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00406 7.76e-68 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00407 5.13e-170 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00408 2.13e-44 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
HOCMNKEB_00409 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
HOCMNKEB_00410 1.43e-97 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
HOCMNKEB_00411 1.17e-26 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
HOCMNKEB_00412 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HOCMNKEB_00413 1.49e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOCMNKEB_00414 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOCMNKEB_00415 1.07e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HOCMNKEB_00416 4.19e-53 - - - P - - - membrane protein (DUF2207)
HOCMNKEB_00417 1.27e-77 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_00418 2.94e-300 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOCMNKEB_00419 2.33e-162 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOCMNKEB_00420 9.02e-276 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOCMNKEB_00421 4.34e-200 - - - S - - - Phospholipase, patatin family
HOCMNKEB_00422 8.11e-44 - - - E - - - GDSL-like protein
HOCMNKEB_00423 2.86e-83 - - - E - - - Lysophospholipase L1 and related esterases
HOCMNKEB_00424 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
HOCMNKEB_00425 7.16e-52 - - - S - - - granule-associated protein
HOCMNKEB_00426 4.17e-50 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HOCMNKEB_00427 9.22e-171 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HOCMNKEB_00428 1.74e-22 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HOCMNKEB_00429 1.68e-254 XK27_12525 - - S - - - hmm pf01594
HOCMNKEB_00430 3.54e-112 - - - G - - - Belongs to the phosphoglycerate mutase family
HOCMNKEB_00431 7.09e-88 supH 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
HOCMNKEB_00432 3.2e-19 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
HOCMNKEB_00433 4.13e-121 - - - S - - - Glycosyltransferase like family 2
HOCMNKEB_00434 1.25e-115 - - - L ko:K07498 - ko00000 DDE domain
HOCMNKEB_00435 4.03e-207 - - - L - - - Transposase DDE domain
HOCMNKEB_00436 6.38e-29 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
HOCMNKEB_00437 3.65e-316 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HOCMNKEB_00438 2.9e-150 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
HOCMNKEB_00439 3.89e-147 capA - - M - - - biosynthesis protein
HOCMNKEB_00440 3.83e-174 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
HOCMNKEB_00441 7.45e-314 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HOCMNKEB_00442 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
HOCMNKEB_00443 2.9e-155 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
HOCMNKEB_00444 4.94e-69 clcA2 - - P - - - chloride
HOCMNKEB_00445 4.15e-191 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HOCMNKEB_00446 7.33e-81 - - - S - - - Protein of unknown function (DUF1697)
HOCMNKEB_00447 1.56e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HOCMNKEB_00448 7.14e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOCMNKEB_00450 5.99e-11 - - - V - - - Glucan-binding protein C
HOCMNKEB_00451 1.13e-144 ung2 - - L - - - Uracil-DNA glycosylase
HOCMNKEB_00452 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
HOCMNKEB_00453 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HOCMNKEB_00454 5.58e-62 XK27_03610 - - K - - - Gnat family
HOCMNKEB_00455 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOCMNKEB_00456 5.79e-39 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HOCMNKEB_00457 3.15e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOCMNKEB_00458 8.33e-156 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HOCMNKEB_00459 1.34e-87 XK27_09115 - - M - - - LysM domain
HOCMNKEB_00460 1.12e-119 ebsA - - S - - - Family of unknown function (DUF5322)
HOCMNKEB_00461 6.13e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HOCMNKEB_00462 1.95e-127 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HOCMNKEB_00463 1.34e-285 XK27_05225 - - G - - - COG0457 FOG TPR repeat
HOCMNKEB_00464 1.22e-231 XK27_05220 - - S - - - permease
HOCMNKEB_00465 3.52e-120 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HOCMNKEB_00466 1.99e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HOCMNKEB_00467 2.1e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HOCMNKEB_00468 2.18e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOCMNKEB_00469 1.52e-263 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HOCMNKEB_00470 2.13e-231 - - - S - - - Calcineurin-like phosphoesterase
HOCMNKEB_00471 1.38e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HOCMNKEB_00472 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
HOCMNKEB_00473 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
HOCMNKEB_00474 1.42e-68 XK27_00115 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
HOCMNKEB_00475 4.65e-188 XK27_00835 - - S - - - hydrolases of the HAD superfamily
HOCMNKEB_00476 1.05e-293 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
HOCMNKEB_00477 1.77e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
HOCMNKEB_00478 1.86e-316 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HOCMNKEB_00479 1.44e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCMNKEB_00480 3.14e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00481 5.66e-193 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HOCMNKEB_00482 8.31e-159 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00483 6.09e-144 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HOCMNKEB_00484 6.78e-177 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HOCMNKEB_00485 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
HOCMNKEB_00486 3.41e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOCMNKEB_00488 1.81e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HOCMNKEB_00489 7.65e-17 - - - G - - - Domain of unknown function (DUF4832)
HOCMNKEB_00490 5.75e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOCMNKEB_00491 2.38e-223 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOCMNKEB_00492 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOCMNKEB_00493 1.12e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HOCMNKEB_00494 5.22e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOCMNKEB_00495 1.9e-27 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HOCMNKEB_00498 5.73e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOCMNKEB_00499 1.13e-274 - - - P - - - chloride
HOCMNKEB_00500 4.26e-54 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
HOCMNKEB_00501 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
HOCMNKEB_00502 4.07e-97 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HOCMNKEB_00504 2.2e-162 XK27_08875 - - O - - - Zinc-dependent metalloprotease
HOCMNKEB_00505 1.84e-194 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
HOCMNKEB_00506 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOCMNKEB_00507 4.44e-173 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00508 9.64e-191 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HOCMNKEB_00509 4.13e-230 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
HOCMNKEB_00510 5.6e-17 - - - S - - - Domain of unknown function (DUF4649)
HOCMNKEB_00512 1.24e-49 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_00513 1.12e-33 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_00515 6.86e-11 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_00517 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HOCMNKEB_00518 1.04e-239 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOCMNKEB_00519 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HOCMNKEB_00520 1.99e-194 XK27_00020 - - J - - - Belongs to the SUA5 family
HOCMNKEB_00521 2.76e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOCMNKEB_00522 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOCMNKEB_00523 1.64e-57 ysdA - - L - - - Membrane
HOCMNKEB_00524 1.02e-239 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HOCMNKEB_00525 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOCMNKEB_00526 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOCMNKEB_00527 2.31e-230 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
HOCMNKEB_00529 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOCMNKEB_00530 4.93e-123 ypmS - - S - - - Protein conserved in bacteria
HOCMNKEB_00531 1.8e-186 ypmR - - E - - - lipolytic protein G-D-S-L family
HOCMNKEB_00532 3.39e-190 WQ51_01275 - - S - - - DegV family
HOCMNKEB_00533 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HOCMNKEB_00534 4.21e-95 argR - - K ko:K03402 - ko00000,ko03000 arginine binding
HOCMNKEB_00535 1.64e-202 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HOCMNKEB_00536 1.64e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HOCMNKEB_00537 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
HOCMNKEB_00538 9.08e-314 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOCMNKEB_00541 3.81e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOCMNKEB_00542 9.02e-163 dnaD - - - ko:K02086 - ko00000 -
HOCMNKEB_00543 2.81e-232 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOCMNKEB_00544 6.44e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOCMNKEB_00545 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
HOCMNKEB_00546 4.46e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCMNKEB_00547 1.27e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HOCMNKEB_00548 6.66e-151 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
HOCMNKEB_00549 3.89e-284 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOCMNKEB_00550 0.0 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HOCMNKEB_00551 7.62e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP
HOCMNKEB_00552 2.98e-80 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOCMNKEB_00553 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOCMNKEB_00554 1.75e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HOCMNKEB_00555 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOCMNKEB_00556 2.75e-136 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HOCMNKEB_00557 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOCMNKEB_00558 4.86e-150 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HOCMNKEB_00559 5.26e-234 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HOCMNKEB_00560 5.82e-250 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOCMNKEB_00562 1.74e-42 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_00563 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOCMNKEB_00564 3.31e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
HOCMNKEB_00565 7.22e-283 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
HOCMNKEB_00566 4.25e-271 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HOCMNKEB_00567 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOCMNKEB_00568 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HOCMNKEB_00569 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCMNKEB_00570 6.93e-236 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCMNKEB_00572 6.81e-92 - - - L - - - Transposase (IS116 IS110 IS902 family)
HOCMNKEB_00573 2.38e-79 - - - L - - - Transposase (IS116 IS110 IS902 family)
HOCMNKEB_00574 9.81e-212 ypuA - - S - - - secreted protein
HOCMNKEB_00575 2.77e-94 ywkD - - E ko:K08234 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HOCMNKEB_00576 5.6e-172 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
HOCMNKEB_00577 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOCMNKEB_00578 2.06e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HOCMNKEB_00579 0.0 noxE - - P - - - NADH oxidase
HOCMNKEB_00580 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
HOCMNKEB_00581 3.05e-75 - - - S - - - ECF-type riboflavin transporter, S component
HOCMNKEB_00582 5.36e-12 - - - S - - - ECF-type riboflavin transporter, S component
HOCMNKEB_00583 1.2e-120 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
HOCMNKEB_00584 1.46e-112 - - - S - - - ECF-type riboflavin transporter, S component
HOCMNKEB_00586 1.21e-303 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCMNKEB_00587 4.59e-75 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
HOCMNKEB_00590 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOCMNKEB_00591 2.07e-118 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCMNKEB_00592 5.02e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOCMNKEB_00593 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HOCMNKEB_00594 6.47e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOCMNKEB_00595 2.57e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOCMNKEB_00596 1.18e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOCMNKEB_00597 2.13e-116 alkD - - L - - - Dna alkylation repair
HOCMNKEB_00598 5.31e-120 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
HOCMNKEB_00599 1.94e-16 - - - - - - - -
HOCMNKEB_00600 2.92e-42 - - - - - - - -
HOCMNKEB_00601 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOCMNKEB_00602 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOCMNKEB_00603 1.76e-164 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
HOCMNKEB_00604 4.18e-82 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
HOCMNKEB_00605 4.15e-120 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HOCMNKEB_00606 2.69e-178 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00607 4.07e-216 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HOCMNKEB_00608 1.09e-143 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00609 0.0 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HOCMNKEB_00610 1.2e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
HOCMNKEB_00611 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HOCMNKEB_00612 1.13e-76 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HOCMNKEB_00613 4.01e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCMNKEB_00614 2.08e-246 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HOCMNKEB_00615 2.48e-171 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HOCMNKEB_00616 1.25e-204 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00620 2.76e-271 - - - EGP - - - Major facilitator Superfamily
HOCMNKEB_00621 0.0 - 2.7.7.73, 2.7.7.80 - E ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 metalloendopeptidase activity
HOCMNKEB_00622 1.23e-194 mutR - - K - - - Transcriptional activator, Rgg GadR MutR family
HOCMNKEB_00623 3.03e-55 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HOCMNKEB_00624 4.55e-286 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HOCMNKEB_00626 1.77e-158 - - - S - - - An automated process has identified a potential problem with this gene model
HOCMNKEB_00627 6.66e-31 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 'abc transporter, ATP-binding protein
HOCMNKEB_00630 2.63e-66 - - - S ko:K06940 - ko00000 Fe-S-cluster oxidoreductase
HOCMNKEB_00631 4.27e-42 - - - S ko:K06940 - ko00000 Fe-S-cluster oxidoreductase
HOCMNKEB_00632 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HOCMNKEB_00633 6.05e-171 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HOCMNKEB_00634 1.2e-215 - - - T - - - Histidine kinase
HOCMNKEB_00635 2.13e-158 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCMNKEB_00636 7.08e-100 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOCMNKEB_00637 3.62e-245 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
HOCMNKEB_00638 4.63e-316 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HOCMNKEB_00639 2.73e-239 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOCMNKEB_00640 4.45e-117 yxeM - - ET ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HOCMNKEB_00641 9.41e-251 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase
HOCMNKEB_00642 2.66e-118 yxeO - - E ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00643 8.13e-93 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00644 1.13e-74 - - - K - - - Acetyltransferase (GNAT) domain
HOCMNKEB_00645 2.28e-140 - - - S - - - MmgE/PrpD family
HOCMNKEB_00646 8.56e-187 ykrV3 - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
HOCMNKEB_00647 2e-128 - - - C ko:K08317 - ko00000,ko01000 glycerol dehydrogenase
HOCMNKEB_00649 1.14e-230 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HOCMNKEB_00650 1.15e-298 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HOCMNKEB_00651 2.11e-87 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HOCMNKEB_00652 6.84e-57 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HOCMNKEB_00653 3.31e-35 csbD - - K - - - CsbD-like
HOCMNKEB_00654 1.54e-292 yfnA - - E ko:K03294 - ko00000 amino acid
HOCMNKEB_00655 1.65e-140 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
HOCMNKEB_00656 6.65e-194 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HOCMNKEB_00657 2.96e-100 ywnA_2 - - K - - - Transcriptional regulator
HOCMNKEB_00658 4.34e-202 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
HOCMNKEB_00659 5.04e-296 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOCMNKEB_00660 2.35e-142 ydgI - - C - - - Nitroreductase
HOCMNKEB_00661 1.33e-136 - - - S - - - Protein of unknown function (DUF1275)
HOCMNKEB_00662 2.73e-204 yvgN - - C - - - reductase
HOCMNKEB_00663 7.53e-229 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HOCMNKEB_00664 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
HOCMNKEB_00666 1.58e-50 BP1961 - - P - - - nitric oxide dioxygenase activity
HOCMNKEB_00667 3.09e-36 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HOCMNKEB_00668 4.87e-23 - - - KT - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_00669 1.07e-86 - - - S - - - Signal peptide protein, YSIRK family
HOCMNKEB_00671 7.57e-70 - - - - - - - -
HOCMNKEB_00672 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCMNKEB_00673 1.14e-217 - - - - - - - -
HOCMNKEB_00674 1.08e-14 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
HOCMNKEB_00676 4.88e-140 - - - E - - - LysE type translocator
HOCMNKEB_00677 6.23e-11 - - - - - - - -
HOCMNKEB_00678 1.96e-12 - - - - - - - -
HOCMNKEB_00679 0.0 - - - M - - - family 8
HOCMNKEB_00681 1.31e-195 - - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MatE
HOCMNKEB_00682 2.93e-10 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
HOCMNKEB_00683 9.95e-138 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HOCMNKEB_00684 1.61e-90 - - - EGP - - - Major Facilitator Superfamily
HOCMNKEB_00685 0.0 - - - I - - - radical SAM domain protein
HOCMNKEB_00687 7.24e-205 - - - K - - - Transcriptional activator, Rgg GadR MutR family
HOCMNKEB_00688 1.88e-194 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_00689 8.81e-114 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_00691 1.37e-109 - - - - - - - -
HOCMNKEB_00692 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
HOCMNKEB_00693 1.08e-291 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HOCMNKEB_00694 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
HOCMNKEB_00695 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
HOCMNKEB_00696 6.59e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HOCMNKEB_00697 6.03e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HOCMNKEB_00698 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
HOCMNKEB_00699 4.69e-282 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HOCMNKEB_00700 1.4e-236 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HOCMNKEB_00701 6.92e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_00702 3.37e-34 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_00703 1.38e-276 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
HOCMNKEB_00704 8.99e-24 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
HOCMNKEB_00705 4.19e-124 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00706 1.49e-54 - - - V ko:K18996,ko:K19171 - ko00000,ko02048,ko03032 (ABC) transporter
HOCMNKEB_00707 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HOCMNKEB_00708 1.03e-80 - - - L - - - Transposase
HOCMNKEB_00709 2.67e-186 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00710 3.94e-60 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00711 8.99e-151 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00712 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HOCMNKEB_00713 5.74e-241 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HOCMNKEB_00714 1.15e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HOCMNKEB_00715 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOCMNKEB_00718 8.07e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCMNKEB_00719 4.58e-224 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HOCMNKEB_00720 5.38e-155 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
HOCMNKEB_00721 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HOCMNKEB_00722 7.75e-170 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HOCMNKEB_00723 1.1e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOCMNKEB_00724 3e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOCMNKEB_00725 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOCMNKEB_00726 6.79e-62 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
HOCMNKEB_00727 8.75e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HOCMNKEB_00728 8.97e-309 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOCMNKEB_00729 7.18e-193 XK27_02985 - - S - - - overlaps another CDS with the same product name
HOCMNKEB_00730 1.63e-190 - - - S - - - overlaps another CDS with the same product name
HOCMNKEB_00731 2.43e-83 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
HOCMNKEB_00732 1.44e-159 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00733 2.73e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
HOCMNKEB_00734 3.46e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_00735 8.41e-260 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_00736 2.01e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00737 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00738 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HOCMNKEB_00739 7.98e-17 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_00740 5.8e-189 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_00741 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HOCMNKEB_00742 7.37e-60 - - - L ko:K07483 - ko00000 Transposase
HOCMNKEB_00743 2.84e-203 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
HOCMNKEB_00744 1.72e-30 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_00745 7.95e-59 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_00746 2.09e-51 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
HOCMNKEB_00747 1.24e-279 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HOCMNKEB_00748 1.22e-143 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_00749 5.73e-33 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_00750 6.82e-25 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_00751 1.15e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HOCMNKEB_00752 7.67e-222 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HOCMNKEB_00753 1.19e-197 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOCMNKEB_00754 5.61e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
HOCMNKEB_00755 5.5e-134 yjbK - - S - - - Adenylate cyclase
HOCMNKEB_00756 2.81e-224 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOCMNKEB_00757 1.12e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HOCMNKEB_00758 5.09e-78 XK27_04120 - - S - - - Putative amino acid metabolism
HOCMNKEB_00759 1.35e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOCMNKEB_00760 4.68e-169 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
HOCMNKEB_00761 2.79e-155 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HOCMNKEB_00762 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
HOCMNKEB_00763 3.59e-283 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HOCMNKEB_00764 6.03e-179 - - - GM ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HOCMNKEB_00765 7.95e-222 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HOCMNKEB_00766 2.41e-281 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
HOCMNKEB_00767 4.78e-221 - - - S - - - Glucosyl transferase GtrII
HOCMNKEB_00768 2.3e-34 - - - S - - - Glucosyl transferase GtrII
HOCMNKEB_00769 3.54e-277 - - GT4 M ko:K00754 - ko00000,ko01000 transferase activity, transferring glycosyl groups
HOCMNKEB_00770 4.29e-276 - - - M - - - Psort location CytoplasmicMembrane, score
HOCMNKEB_00771 0.0 - - - M - - - Glycosyltransferase like family 2
HOCMNKEB_00772 1.07e-192 - - - S - - - Glycosyltransferase group 2 family protein
HOCMNKEB_00773 8e-57 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
HOCMNKEB_00774 9e-166 arnC - - M ko:K00786 - ko00000,ko01000 group 2 family protein
HOCMNKEB_00775 2.14e-231 - - - S - - - Glycosyltransferase like family 2
HOCMNKEB_00776 1.3e-234 - - - S - - - Glycosyltransferase like family 2
HOCMNKEB_00777 8.72e-280 - - - S - - - membrane protein involved in the export of O-antigen and teichoic acid
HOCMNKEB_00778 1.83e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOCMNKEB_00779 0.0 - - - S - - - Glucosyl transferase GtrII
HOCMNKEB_00780 1.87e-218 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
HOCMNKEB_00781 4.86e-74 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
HOCMNKEB_00782 1.44e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOCMNKEB_00783 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOCMNKEB_00784 7.77e-27 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HOCMNKEB_00785 4.07e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HOCMNKEB_00786 2.76e-269 arcT - - E - - - Aminotransferase
HOCMNKEB_00787 1.31e-176 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
HOCMNKEB_00788 6.76e-185 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HOCMNKEB_00789 2.15e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
HOCMNKEB_00790 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOCMNKEB_00792 3.3e-72 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HOCMNKEB_00793 6.37e-40 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
HOCMNKEB_00794 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
HOCMNKEB_00795 1.44e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00796 5.28e-24 XK27_00735 - - - - - - -
HOCMNKEB_00797 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOCMNKEB_00798 8.41e-11 - - - S - - - Protein of unknown function (DUF4044)
HOCMNKEB_00799 2.22e-173 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HOCMNKEB_00802 1.25e-85 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
HOCMNKEB_00803 1.17e-40 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
HOCMNKEB_00805 1.61e-197 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
HOCMNKEB_00807 1.22e-140 csn2 - - S ko:K19137 - ko00000,ko02048 CRISPR-associated protein (Cas_Csn2)
HOCMNKEB_00808 2.82e-71 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOCMNKEB_00809 2.97e-210 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOCMNKEB_00810 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HOCMNKEB_00811 1.76e-147 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
HOCMNKEB_00812 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HOCMNKEB_00813 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOCMNKEB_00814 1.07e-141 - - - S - - - IA, variant 1
HOCMNKEB_00815 9.48e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
HOCMNKEB_00816 5.26e-77 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
HOCMNKEB_00818 2.92e-78 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HOCMNKEB_00819 7.41e-68 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
HOCMNKEB_00820 2.15e-280 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOCMNKEB_00821 5.41e-134 - - - M - - - Acetyltransferase GNAT family
HOCMNKEB_00822 3.61e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOCMNKEB_00823 4.73e-123 - - - GK - - - ROK family
HOCMNKEB_00824 1.61e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
HOCMNKEB_00825 1.56e-71 XK27_08050 - - O - - - stress-induced mitochondrial fusion
HOCMNKEB_00826 4.81e-25 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
HOCMNKEB_00827 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
HOCMNKEB_00828 1.79e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
HOCMNKEB_00829 2e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
HOCMNKEB_00830 1.38e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HOCMNKEB_00831 4.06e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HOCMNKEB_00832 7.94e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOCMNKEB_00833 1.05e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOCMNKEB_00834 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HOCMNKEB_00835 2.6e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOCMNKEB_00836 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
HOCMNKEB_00837 0.0 ydaO - - E - - - amino acid
HOCMNKEB_00838 2.35e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HOCMNKEB_00839 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
HOCMNKEB_00840 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HOCMNKEB_00841 6.55e-220 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
HOCMNKEB_00842 2.43e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HOCMNKEB_00843 1.22e-97 - - - S - - - QueT transporter
HOCMNKEB_00844 4.27e-11 - - - L - - - Transposase DDE domain
HOCMNKEB_00845 1.43e-115 - - - L - - - Transposase DDE domain
HOCMNKEB_00846 7.79e-237 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HOCMNKEB_00847 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOCMNKEB_00848 3.26e-110 ccl - - S - - - cog cog4708
HOCMNKEB_00849 2.38e-210 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
HOCMNKEB_00850 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HOCMNKEB_00851 1.06e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
HOCMNKEB_00852 2.39e-126 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
HOCMNKEB_00853 2.13e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOCMNKEB_00854 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HOCMNKEB_00855 1.95e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HOCMNKEB_00856 2.92e-182 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HOCMNKEB_00857 1.33e-112 nodB3 - - G - - - polysaccharide deacetylase
HOCMNKEB_00858 6.52e-31 nodB3 - - G - - - polysaccharide deacetylase
HOCMNKEB_00859 2.91e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
HOCMNKEB_00860 4.12e-56 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HOCMNKEB_00861 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HOCMNKEB_00862 6.14e-205 corA - - P - - - CorA-like protein
HOCMNKEB_00863 7.5e-83 yjqA - - S - - - Bacterial PH domain
HOCMNKEB_00864 4.57e-129 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
HOCMNKEB_00865 5.28e-203 rgg - - K - - - Transcriptional activator, Rgg GadR MutR family
HOCMNKEB_00866 1.09e-257 yjbB - - G - - - Permeases of the major facilitator superfamily
HOCMNKEB_00867 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HOCMNKEB_00868 1.56e-153 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
HOCMNKEB_00869 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOCMNKEB_00873 2.71e-199 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HOCMNKEB_00874 4.54e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00875 1.4e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00876 8.58e-149 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00877 3.92e-247 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HOCMNKEB_00878 9.48e-43 copZ - - P - - - Heavy metal-associated domain protein
HOCMNKEB_00879 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HOCMNKEB_00880 2.48e-96 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
HOCMNKEB_00881 6.85e-181 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOCMNKEB_00882 1.66e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOCMNKEB_00883 9.2e-130 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
HOCMNKEB_00884 1.54e-170 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HOCMNKEB_00885 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOCMNKEB_00886 2.03e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
HOCMNKEB_00887 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOCMNKEB_00888 1.46e-73 - - - - - - - -
HOCMNKEB_00889 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HOCMNKEB_00891 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOCMNKEB_00892 6.16e-38 - - - L - - - transposase activity
HOCMNKEB_00893 6.01e-167 - - - K - - - transcriptional regulator, MerR family
HOCMNKEB_00894 2.17e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HOCMNKEB_00895 8.12e-80 WQ51_02910 - - S - - - Protein of unknown function, DUF536
HOCMNKEB_00896 1.05e-83 XK27_02560 - - S - - - cog cog2151
HOCMNKEB_00897 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HOCMNKEB_00898 3.35e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
HOCMNKEB_00900 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOCMNKEB_00901 8.46e-197 ytmP - - M - - - Phosphotransferase
HOCMNKEB_00902 5.42e-232 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HOCMNKEB_00903 1.5e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00904 1.76e-94 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HOCMNKEB_00905 3.91e-14 - - - - - - - -
HOCMNKEB_00906 6.49e-81 - - - - - - - -
HOCMNKEB_00907 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
HOCMNKEB_00908 4.36e-263 ylbM - - S - - - Belongs to the UPF0348 family
HOCMNKEB_00909 2.78e-179 XK27_06665 - - Q - - - Methyltransferase domain protein
HOCMNKEB_00910 9.81e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOCMNKEB_00911 2.01e-139 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HOCMNKEB_00912 5.51e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOCMNKEB_00913 1.59e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HOCMNKEB_00914 2.78e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HOCMNKEB_00915 1.84e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HOCMNKEB_00916 3.49e-196 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HOCMNKEB_00917 9.12e-76 - - - - - - - -
HOCMNKEB_00918 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOCMNKEB_00919 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOCMNKEB_00920 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOCMNKEB_00921 6.32e-42 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
HOCMNKEB_00922 9.15e-189 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HOCMNKEB_00923 5.44e-98 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HOCMNKEB_00924 1.38e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOCMNKEB_00925 3.85e-198 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HOCMNKEB_00926 3.02e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
HOCMNKEB_00927 6.34e-182 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HOCMNKEB_00928 2.61e-303 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HOCMNKEB_00929 7.54e-99 XK27_03180 - - T - - - universal stress protein
HOCMNKEB_00932 4.04e-201 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOCMNKEB_00933 2.02e-304 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
HOCMNKEB_00934 1.29e-185 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00935 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
HOCMNKEB_00937 9e-127 mraW1 - - J - - - (SAM)-dependent
HOCMNKEB_00938 1.77e-235 ytqA - - S ko:K07139 - ko00000 radical SAM protein
HOCMNKEB_00939 7.98e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HOCMNKEB_00940 7.91e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOCMNKEB_00941 9.01e-121 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HOCMNKEB_00942 4.78e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOCMNKEB_00943 7.33e-14 - - - S - - - Protein of unknown function (DUF4059)
HOCMNKEB_00944 9.69e-170 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_00945 2.53e-208 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_00946 1.27e-195 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HOCMNKEB_00948 2.53e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCMNKEB_00949 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
HOCMNKEB_00950 6.92e-190 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
HOCMNKEB_00951 9.32e-112 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCMNKEB_00952 5.58e-60 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
HOCMNKEB_00953 1.96e-113 - - - D - - - nuclear chromosome segregation
HOCMNKEB_00954 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HOCMNKEB_00955 2.51e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00956 4.14e-235 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
HOCMNKEB_00957 6.61e-179 cppA - - E - - - CppA N-terminal
HOCMNKEB_00958 2.69e-56 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HOCMNKEB_00959 7.59e-212 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HOCMNKEB_00960 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HOCMNKEB_00963 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
HOCMNKEB_00964 9.35e-36 blpT - - - - - - -
HOCMNKEB_00965 4.64e-159 blpT - - - - - - -
HOCMNKEB_00969 0.000703 - - - - - - - -
HOCMNKEB_00970 2.55e-33 - - - S - - - Bacteriocin class II with double-glycine leader peptide
HOCMNKEB_00973 1.5e-171 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
HOCMNKEB_00974 2.32e-298 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
HOCMNKEB_00976 2.91e-310 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HOCMNKEB_00977 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HOCMNKEB_00978 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00979 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00981 2.82e-122 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
HOCMNKEB_00982 1.58e-285 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOCMNKEB_00983 2.44e-139 yutD - - J - - - protein conserved in bacteria
HOCMNKEB_00984 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_00986 2.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HOCMNKEB_00987 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOCMNKEB_00988 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
HOCMNKEB_00989 1.85e-60 ftsL - - D - - - cell division protein FtsL
HOCMNKEB_00990 2.67e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOCMNKEB_00991 1.83e-163 - - - - - - - -
HOCMNKEB_00992 3.7e-41 - - - J - - - Protein of unknown function (DUF805)
HOCMNKEB_00993 1.38e-16 - - - D - - - nuclear chromosome segregation
HOCMNKEB_00994 1.22e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOCMNKEB_00995 4.99e-182 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOCMNKEB_00996 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HOCMNKEB_00997 2.59e-172 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_00998 1.22e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HOCMNKEB_00999 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HOCMNKEB_01000 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HOCMNKEB_01001 6.55e-72 - - - S - - - membrane
HOCMNKEB_01002 4.73e-14 XK27_02470 - - K - - - LytTr DNA-binding domain protein
HOCMNKEB_01003 5.01e-79 - - - KT - - - response to antibiotic
HOCMNKEB_01004 2.99e-127 yebC - - M - - - Membrane
HOCMNKEB_01005 1.77e-24 yebC - - M - - - Membrane
HOCMNKEB_01006 0.0 - - - S - - - hydrolases of the HAD superfamily
HOCMNKEB_01007 8.08e-223 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HOCMNKEB_01008 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOCMNKEB_01009 1.92e-243 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOCMNKEB_01010 1.75e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOCMNKEB_01011 1.01e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOCMNKEB_01012 2.03e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOCMNKEB_01013 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOCMNKEB_01015 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HOCMNKEB_01016 2.37e-220 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
HOCMNKEB_01017 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01018 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HOCMNKEB_01019 3.67e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
HOCMNKEB_01020 2.67e-96 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOCMNKEB_01021 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
HOCMNKEB_01022 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOCMNKEB_01023 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HOCMNKEB_01024 2.5e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
HOCMNKEB_01026 6.03e-55 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
HOCMNKEB_01027 3.94e-75 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
HOCMNKEB_01034 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOCMNKEB_01035 1.98e-298 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HOCMNKEB_01036 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
HOCMNKEB_01037 1.44e-72 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HOCMNKEB_01038 1.13e-125 XK27_03570 - - S ko:K19784 - ko00000 reductase
HOCMNKEB_01039 3.79e-116 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_01040 1.2e-54 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_01042 1.88e-99 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 carboxypeptidase activity
HOCMNKEB_01043 1.56e-103 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HOCMNKEB_01045 4.11e-175 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HOCMNKEB_01046 1.73e-232 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOCMNKEB_01047 3.55e-109 - - - S - - - Putative small multi-drug export protein
HOCMNKEB_01048 2.83e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HOCMNKEB_01049 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HOCMNKEB_01050 6.9e-194 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HOCMNKEB_01051 3.56e-65 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HOCMNKEB_01052 5.4e-293 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HOCMNKEB_01053 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HOCMNKEB_01054 7.76e-185 - - - S - - - SseB protein N-terminal domain
HOCMNKEB_01055 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
HOCMNKEB_01056 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HOCMNKEB_01057 2.1e-90 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOCMNKEB_01060 1.23e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOCMNKEB_01061 2.45e-111 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HOCMNKEB_01062 2.6e-198 yitS - - S - - - DegV family
HOCMNKEB_01063 1.22e-42 - - - K - - - helix-turn-helix
HOCMNKEB_01064 4e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOCMNKEB_01065 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOCMNKEB_01066 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HOCMNKEB_01067 3.13e-138 int - - L - - - Belongs to the 'phage' integrase family
HOCMNKEB_01068 5.71e-104 int - - L - - - Belongs to the 'phage' integrase family
HOCMNKEB_01069 1.05e-54 - - - S - - - Helix-turn-helix domain
HOCMNKEB_01070 1.07e-218 - - - - - - - -
HOCMNKEB_01071 4.04e-95 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
HOCMNKEB_01072 6.53e-118 - - - L ko:K07498 - ko00000 Transposase
HOCMNKEB_01073 1.3e-283 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
HOCMNKEB_01074 1.76e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
HOCMNKEB_01075 1.6e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HOCMNKEB_01076 4.76e-50 ais - - G - - - alpha-ribazole phosphatase activity
HOCMNKEB_01077 4.65e-186 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HOCMNKEB_01078 5.34e-134 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
HOCMNKEB_01079 4.82e-254 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOCMNKEB_01080 2.93e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOCMNKEB_01081 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HOCMNKEB_01082 1.02e-259 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOCMNKEB_01085 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HOCMNKEB_01086 6.01e-218 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
HOCMNKEB_01087 5.06e-160 - - - S - - - Pfam PF06570
HOCMNKEB_01089 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOCMNKEB_01090 2.07e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOCMNKEB_01091 3.11e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HOCMNKEB_01092 3.53e-51 XK27_05745 - - - - - - -
HOCMNKEB_01093 9.59e-293 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HOCMNKEB_01097 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOCMNKEB_01098 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOCMNKEB_01099 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
HOCMNKEB_01100 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HOCMNKEB_01101 4.7e-206 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOCMNKEB_01102 2.62e-145 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HOCMNKEB_01103 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOCMNKEB_01104 3.85e-63 azlD - - E - - - branched-chain amino acid
HOCMNKEB_01105 7.55e-150 XK27_12120 - - E - - - AzlC protein
HOCMNKEB_01106 1.64e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOCMNKEB_01107 1.54e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HOCMNKEB_01108 5.62e-155 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
HOCMNKEB_01109 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
HOCMNKEB_01110 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOCMNKEB_01111 4.75e-53 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
HOCMNKEB_01112 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HOCMNKEB_01113 1.12e-83 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HOCMNKEB_01114 1.08e-113 - - - S - - - Fusaric acid resistance protein-like
HOCMNKEB_01115 1.94e-16 - - - - - - - -
HOCMNKEB_01116 9.51e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HOCMNKEB_01117 4.29e-57 - - - L ko:K07491 - ko00000 Transposase
HOCMNKEB_01118 6.62e-62 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_01119 2.82e-29 - - - L - - - Transposase
HOCMNKEB_01120 3.23e-75 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_01121 4.35e-108 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_01122 7.61e-289 - - - L ko:K07485 - ko00000 Helix-turn-helix domain of transposase family ISL3
HOCMNKEB_01123 3.33e-242 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOCMNKEB_01124 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOCMNKEB_01125 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOCMNKEB_01126 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOCMNKEB_01127 1.8e-183 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
HOCMNKEB_01128 2.28e-227 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
HOCMNKEB_01129 4.63e-236 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
HOCMNKEB_01130 2.73e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HOCMNKEB_01131 2.76e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HOCMNKEB_01132 6.21e-208 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOCMNKEB_01134 1.57e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOCMNKEB_01135 1.81e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HOCMNKEB_01136 2.13e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
HOCMNKEB_01137 9.39e-98 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HOCMNKEB_01138 5.36e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HOCMNKEB_01139 5.03e-183 - - - S - - - Macro domain protein
HOCMNKEB_01140 2.59e-13 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
HOCMNKEB_01141 3.38e-72 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
HOCMNKEB_01144 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOCMNKEB_01145 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
HOCMNKEB_01146 7.21e-239 jag - - S ko:K06346 - ko00000 RNA-binding protein
HOCMNKEB_01147 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOCMNKEB_01148 8.28e-73 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOCMNKEB_01149 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
HOCMNKEB_01150 3.19e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOCMNKEB_01151 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOCMNKEB_01152 3.68e-107 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
HOCMNKEB_01153 1.5e-217 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HOCMNKEB_01154 2.24e-32 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HOCMNKEB_01155 1.66e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOCMNKEB_01156 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOCMNKEB_01157 3.28e-66 - - - S - - - Protein of unknown function (DUF3397)
HOCMNKEB_01158 9.62e-116 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HOCMNKEB_01159 1.15e-47 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
HOCMNKEB_01160 1.64e-16 - - - S - - - Mitochondrial biogenesis AIM24
HOCMNKEB_01161 1.08e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOCMNKEB_01162 2.98e-104 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HOCMNKEB_01163 3.06e-27 XK27_09620 - - S - - - FMN reductase (NADPH) activity
HOCMNKEB_01164 1.16e-97 - - - S - - - reductase
HOCMNKEB_01165 2.87e-272 XK27_09615 - - C ko:K19784 - ko00000 reductase
HOCMNKEB_01166 9.06e-148 nirC_1 - - P - - - Formate nitrite transporter
HOCMNKEB_01167 3.82e-82 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HOCMNKEB_01168 2.95e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HOCMNKEB_01169 9.25e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HOCMNKEB_01170 2.39e-154 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HOCMNKEB_01171 4.01e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOCMNKEB_01172 1.34e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HOCMNKEB_01173 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HOCMNKEB_01174 7.38e-61 - - - S ko:K07025 - ko00000 glycolate biosynthetic process
HOCMNKEB_01175 5.33e-86 - - - S ko:K07025 - ko00000 phosphatase activity
HOCMNKEB_01176 1.41e-202 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
HOCMNKEB_01179 5.94e-118 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOCMNKEB_01180 1.81e-85 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOCMNKEB_01181 2.25e-49 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
HOCMNKEB_01182 2.24e-239 yeeE - - S ko:K07112 - ko00000 Sulphur transport
HOCMNKEB_01183 5.51e-147 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOCMNKEB_01184 5.78e-72 ytpP - - CO - - - Thioredoxin
HOCMNKEB_01186 1.84e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HOCMNKEB_01187 1.17e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOCMNKEB_01188 1.13e-141 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
HOCMNKEB_01190 1.93e-87 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HOCMNKEB_01191 1.05e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
HOCMNKEB_01192 3.27e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOCMNKEB_01193 3.39e-226 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HOCMNKEB_01194 3.67e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HOCMNKEB_01195 1.87e-92 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
HOCMNKEB_01196 3.66e-21 - - - NU - - - Type II secretory pathway pseudopilin
HOCMNKEB_01197 4.21e-75 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
HOCMNKEB_01198 2.23e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HOCMNKEB_01199 1.86e-196 cglB - - U ko:K02244 - ko00000,ko00002,ko02044 protein transport across the cell outer membrane
HOCMNKEB_01200 2.2e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HOCMNKEB_01201 3.93e-91 - - - S - - - cog cog4699
HOCMNKEB_01202 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOCMNKEB_01203 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOCMNKEB_01204 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HOCMNKEB_01205 2.04e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOCMNKEB_01206 5.16e-248 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOCMNKEB_01207 2.89e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HOCMNKEB_01208 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HOCMNKEB_01209 1.64e-181 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HOCMNKEB_01210 7.43e-151 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HOCMNKEB_01211 1.57e-11 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HOCMNKEB_01212 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HOCMNKEB_01213 1.87e-76 asp - - S - - - cog cog1302
HOCMNKEB_01214 1.12e-287 norN - - V - - - Mate efflux family protein
HOCMNKEB_01215 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HOCMNKEB_01216 4.9e-76 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HOCMNKEB_01217 2.68e-31 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 hydroxyacid-oxoacid transhydrogenase activity
HOCMNKEB_01218 3.72e-97 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HOCMNKEB_01219 1.17e-162 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HOCMNKEB_01220 1.37e-69 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
HOCMNKEB_01221 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HOCMNKEB_01222 3.67e-49 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HOCMNKEB_01223 4.39e-90 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HOCMNKEB_01224 4.14e-87 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HOCMNKEB_01225 3.49e-72 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
HOCMNKEB_01226 2.66e-29 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
HOCMNKEB_01227 1.53e-112 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
HOCMNKEB_01228 1.6e-122 ywlG - - S - - - Belongs to the UPF0340 family
HOCMNKEB_01231 7.56e-45 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HOCMNKEB_01232 1.76e-120 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HOCMNKEB_01233 2.79e-55 - - - K - - - Putative DNA-binding domain
HOCMNKEB_01234 3.75e-18 - - - M - - - Acetyltransferase GNAT Family
HOCMNKEB_01239 2.03e-53 - - - - - - - -
HOCMNKEB_01240 4.01e-41 - - - - - - - -
HOCMNKEB_01241 2.68e-41 - - - S - - - Hypothetical protein (DUF2513)
HOCMNKEB_01242 0.000346 - - - - - - - -
HOCMNKEB_01244 1.14e-277 - - - S - - - MvaI/BcnI restriction endonuclease family
HOCMNKEB_01245 5.73e-05 - - - K - - - Cro/C1-type HTH DNA-binding domain
HOCMNKEB_01246 0.0 - - - H - - - C-5 cytosine-specific DNA methylase
HOCMNKEB_01247 2.34e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
HOCMNKEB_01249 5.67e-84 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
HOCMNKEB_01250 2.06e-44 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
HOCMNKEB_01251 2.93e-23 - - - H - - - gamma-glutamylcysteine synthetase
HOCMNKEB_01252 6.93e-15 - - - H - - - gamma-glutamylcysteine synthetase
HOCMNKEB_01253 5.1e-12 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HOCMNKEB_01254 3.04e-141 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HOCMNKEB_01255 2.13e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
HOCMNKEB_01256 5.37e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOCMNKEB_01257 1.57e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOCMNKEB_01258 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOCMNKEB_01259 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HOCMNKEB_01260 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOCMNKEB_01261 3.7e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOCMNKEB_01262 1.23e-292 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOCMNKEB_01263 1.03e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HOCMNKEB_01264 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
HOCMNKEB_01265 9.94e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOCMNKEB_01266 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOCMNKEB_01267 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOCMNKEB_01268 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOCMNKEB_01269 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOCMNKEB_01270 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOCMNKEB_01271 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOCMNKEB_01272 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOCMNKEB_01273 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOCMNKEB_01274 4.36e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HOCMNKEB_01275 3.58e-93 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOCMNKEB_01276 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOCMNKEB_01277 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOCMNKEB_01278 1.99e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOCMNKEB_01279 7.19e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOCMNKEB_01280 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOCMNKEB_01281 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HOCMNKEB_01282 7.78e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOCMNKEB_01283 7.41e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HOCMNKEB_01284 1.78e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOCMNKEB_01285 0.0 XK27_09800 - - I - - - Acyltransferase
HOCMNKEB_01286 2.43e-47 - - - S - - - MORN repeat protein
HOCMNKEB_01287 2.29e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOCMNKEB_01288 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOCMNKEB_01289 2.62e-116 flaR - - F - - - topology modulation protein
HOCMNKEB_01290 1.98e-17 - - - K - - - Transcriptional activator, Rgg GadR MutR family
HOCMNKEB_01291 2.7e-164 Z012_04635 - - K - - - sequence-specific DNA binding
HOCMNKEB_01293 9.82e-21 - - - C ko:K06871 - ko00000 Radical SAM
HOCMNKEB_01294 1.85e-243 - - - C ko:K06871 - ko00000 Radical SAM
HOCMNKEB_01295 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HOCMNKEB_01296 1.71e-116 - - - K - - - sequence-specific DNA binding
HOCMNKEB_01297 2.46e-54 - - - L - - - Replication initiation factor
HOCMNKEB_01298 2.81e-137 - - - L - - - Replication initiation factor
HOCMNKEB_01299 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
HOCMNKEB_01300 6.11e-278 - - - L - - - Belongs to the 'phage' integrase family
HOCMNKEB_01302 3.74e-303 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
HOCMNKEB_01303 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HOCMNKEB_01304 1.97e-58 yrzL - - S - - - Belongs to the UPF0297 family
HOCMNKEB_01305 2.06e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOCMNKEB_01306 6.38e-61 yrzB - - S - - - Belongs to the UPF0473 family
HOCMNKEB_01307 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_01308 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HOCMNKEB_01309 7.68e-20 - - - - - - - -
HOCMNKEB_01310 1.87e-118 - - - K - - - acetyltransferase
HOCMNKEB_01311 1.26e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOCMNKEB_01312 4.85e-189 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HOCMNKEB_01313 5.96e-213 XK27_01785 - - S - - - cog cog1284
HOCMNKEB_01314 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HOCMNKEB_01316 2.9e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HOCMNKEB_01317 2.37e-171 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HOCMNKEB_01318 1.32e-37 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HOCMNKEB_01319 4.33e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HOCMNKEB_01320 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HOCMNKEB_01321 4.31e-37 - - - - - - - -
HOCMNKEB_01322 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HOCMNKEB_01324 1.45e-48 - - - - - - - -
HOCMNKEB_01325 1.75e-202 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HOCMNKEB_01327 4.36e-106 - - - S - - - Plasmid replication protein
HOCMNKEB_01328 1.29e-27 - - - S - - - MerR HTH family regulatory protein
HOCMNKEB_01329 1.85e-230 - - - L - - - Belongs to the 'phage' integrase family
HOCMNKEB_01332 5.2e-62 yegS - - I - - - Diacylglycerol kinase
HOCMNKEB_01333 1.2e-123 - - - S - - - Hydrophobic domain protein
HOCMNKEB_01335 9.33e-44 ytgB - - S - - - Membrane
HOCMNKEB_01336 6.04e-110 - - - - - - - -
HOCMNKEB_01337 7.53e-33 - - - S - - - Small integral membrane protein
HOCMNKEB_01338 1.31e-116 - - - M - - - Protein conserved in bacteria
HOCMNKEB_01339 1.66e-34 - - - K - - - CsbD-like
HOCMNKEB_01340 2.69e-11 XK27_06885 - - L - - - hydrolase
HOCMNKEB_01341 1.3e-26 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
HOCMNKEB_01342 4.32e-33 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
HOCMNKEB_01343 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
HOCMNKEB_01344 1.79e-27 - - - S - - - Protein of unknown function (DUF1700)
HOCMNKEB_01345 9.42e-73 - - - S - - - Putative adhesin
HOCMNKEB_01346 1.3e-30 - - - S - - - Putative adhesin
HOCMNKEB_01347 9.54e-268 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HOCMNKEB_01348 3.98e-124 XK27_06935 - - K - - - transcriptional regulator
HOCMNKEB_01349 7.97e-73 XK27_04840 - - M ko:K08987 - ko00000 Membrane
HOCMNKEB_01350 2.05e-09 - - - - - - - -
HOCMNKEB_01351 5.92e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOCMNKEB_01352 3.05e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
HOCMNKEB_01353 1.29e-312 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HOCMNKEB_01354 1.24e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HOCMNKEB_01355 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HOCMNKEB_01356 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOCMNKEB_01357 1.46e-101 - - - F - - - NUDIX domain
HOCMNKEB_01358 1.62e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOCMNKEB_01359 0.0 - - - S - - - Bacterial membrane protein, YfhO
HOCMNKEB_01360 5.49e-123 isaA - - M - - - Immunodominant staphylococcal antigen A
HOCMNKEB_01361 1.87e-120 lytE - - M - - - LysM domain protein
HOCMNKEB_01362 2.1e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOCMNKEB_01363 1.5e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOCMNKEB_01364 4.68e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOCMNKEB_01365 5.4e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOCMNKEB_01366 8.84e-185 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
HOCMNKEB_01367 6.27e-308 ymfH - - S - - - Peptidase M16
HOCMNKEB_01368 5.15e-198 albE - - S - - - Peptidase M16
HOCMNKEB_01369 4.22e-84 albE - - S - - - Peptidase M16
HOCMNKEB_01370 3.7e-69 yaaA - - S - - - S4 domain protein YaaA
HOCMNKEB_01371 2.24e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOCMNKEB_01372 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HOCMNKEB_01373 1.17e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HOCMNKEB_01374 3.96e-195 XK27_10395 - - S - - - membrane
HOCMNKEB_01375 0.0 ykpA - - S - - - abc transporter atp-binding protein
HOCMNKEB_01376 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
HOCMNKEB_01380 3.66e-155 yveI - - S - - - Psort location CytoplasmicMembrane, score
HOCMNKEB_01381 2.55e-111 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOCMNKEB_01382 1.49e-260 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HOCMNKEB_01383 9.27e-172 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HOCMNKEB_01384 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOCMNKEB_01385 1.1e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOCMNKEB_01386 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
HOCMNKEB_01387 1.51e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOCMNKEB_01388 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOCMNKEB_01389 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOCMNKEB_01390 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HOCMNKEB_01391 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HOCMNKEB_01392 1.94e-05 - - - - - - - -
HOCMNKEB_01393 3.78e-307 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
HOCMNKEB_01394 8.87e-306 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOCMNKEB_01395 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HOCMNKEB_01396 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOCMNKEB_01397 1.79e-41 - - - - - - - -
HOCMNKEB_01398 1.93e-171 - - - L - - - Transposase
HOCMNKEB_01399 6.62e-62 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_01400 1.74e-30 - - - L - - - Transposase
HOCMNKEB_01401 7.11e-39 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_01402 1.4e-123 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
HOCMNKEB_01403 2.06e-200 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_01404 1.08e-271 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HOCMNKEB_01405 4.44e-272 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HOCMNKEB_01406 1.25e-303 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HOCMNKEB_01407 1.88e-109 - - - M - - - Glycosyltransferase like family 2
HOCMNKEB_01408 2.67e-78 ywqD - - D - - - Capsular exopolysaccharide family
HOCMNKEB_01409 1.61e-126 - - - M - - - group 2 family protein
HOCMNKEB_01410 2.6e-127 - - - - - - - -
HOCMNKEB_01412 5.45e-159 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOCMNKEB_01413 5.34e-176 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
HOCMNKEB_01414 3.57e-43 - - - L - - - Psort location Cytoplasmic, score
HOCMNKEB_01416 7.45e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOCMNKEB_01417 3.02e-176 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
HOCMNKEB_01418 7.01e-81 hmpT - - S - - - membrane
HOCMNKEB_01419 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
HOCMNKEB_01420 1.86e-67 - - - L - - - Transposase
HOCMNKEB_01421 0.0 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_01423 3.11e-219 - - - L - - - Transposase
HOCMNKEB_01425 1e-74 amd - - E - - - COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HOCMNKEB_01426 9.3e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HOCMNKEB_01427 1e-112 - - - - - - - -
HOCMNKEB_01428 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
HOCMNKEB_01429 5.87e-192 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HOCMNKEB_01430 6.47e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOCMNKEB_01431 3.71e-119 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HOCMNKEB_01432 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOCMNKEB_01433 1.45e-108 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
HOCMNKEB_01434 1.08e-106 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HOCMNKEB_01435 5.2e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HOCMNKEB_01436 7.42e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOCMNKEB_01437 2.32e-35 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_01438 3.36e-81 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_01439 5.19e-59 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_01440 3.21e-232 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HOCMNKEB_01441 8.28e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HOCMNKEB_01442 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOCMNKEB_01443 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOCMNKEB_01444 2.99e-10 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
HOCMNKEB_01445 3.58e-33 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
HOCMNKEB_01446 9.76e-23 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
HOCMNKEB_01447 3.02e-65 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
HOCMNKEB_01448 9.52e-303 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HOCMNKEB_01449 2.96e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOCMNKEB_01450 1.63e-146 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HOCMNKEB_01451 2.59e-258 XK27_00055 - - P - - - Major Facilitator
HOCMNKEB_01452 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOCMNKEB_01453 8.47e-126 - - - V - - - VanZ like family
HOCMNKEB_01454 3e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_01455 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HOCMNKEB_01456 2.48e-196 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOCMNKEB_01457 3.52e-173 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HOCMNKEB_01458 5.94e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HOCMNKEB_01459 5.43e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HOCMNKEB_01460 1.7e-298 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HOCMNKEB_01461 1.7e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOCMNKEB_01462 1.13e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HOCMNKEB_01463 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HOCMNKEB_01464 5.77e-13 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HOCMNKEB_01465 1.34e-178 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HOCMNKEB_01466 9e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCMNKEB_01467 4.03e-14 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCMNKEB_01468 4.52e-54 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCMNKEB_01469 3.48e-12 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCMNKEB_01470 3.42e-50 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCMNKEB_01471 9.63e-38 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_01472 1.15e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_01473 1.53e-82 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_01474 1.97e-53 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_01475 1.75e-78 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_01476 2.62e-85 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HOCMNKEB_01477 1.87e-29 - - - - - - - -
HOCMNKEB_01478 1.65e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOCMNKEB_01479 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOCMNKEB_01480 5.96e-284 - - - EGP - - - Major facilitator Superfamily
HOCMNKEB_01481 1.28e-94 adcR - - K - - - transcriptional
HOCMNKEB_01482 8.76e-176 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HOCMNKEB_01483 3.81e-167 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_01484 2.93e-208 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HOCMNKEB_01485 3.9e-37 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01486 1.42e-197 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01487 4.61e-136 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HOCMNKEB_01488 2e-201 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
HOCMNKEB_01489 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HOCMNKEB_01490 3.92e-163 yeeN - - K - - - transcriptional regulatory protein
HOCMNKEB_01491 9.27e-66 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
HOCMNKEB_01492 1.76e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOCMNKEB_01493 1.83e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HOCMNKEB_01494 7.72e-295 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HOCMNKEB_01495 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOCMNKEB_01496 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
HOCMNKEB_01497 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_01498 4.47e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOCMNKEB_01499 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOCMNKEB_01500 3.93e-49 - - - L - - - Transposase
HOCMNKEB_01501 5.61e-26 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_01502 4.68e-66 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_01503 8.38e-46 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_01505 1.58e-55 - - - - - - - -
HOCMNKEB_01506 1.09e-72 WQ51_06355 - - S - - - TM2 domain
HOCMNKEB_01507 9.2e-210 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HOCMNKEB_01508 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HOCMNKEB_01509 6.28e-35 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
HOCMNKEB_01510 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HOCMNKEB_01511 1.17e-110 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
HOCMNKEB_01512 6.76e-73 cof - - Q - - - phosphatase activity
HOCMNKEB_01513 1.89e-47 cof - - Q - - - phosphatase activity
HOCMNKEB_01514 6.57e-176 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
HOCMNKEB_01515 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HOCMNKEB_01516 1.73e-53 napB - - K - - - transcriptional
HOCMNKEB_01517 4.91e-07 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HOCMNKEB_01518 1.47e-100 - - - S ko:K06889 - ko00000 thiolester hydrolase activity
HOCMNKEB_01519 2.49e-179 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HOCMNKEB_01520 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOCMNKEB_01521 6.15e-195 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HOCMNKEB_01522 9.64e-100 yhaI - - L - - - Membrane
HOCMNKEB_01523 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HOCMNKEB_01524 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HOCMNKEB_01525 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOCMNKEB_01526 8.82e-124 ypsA - - S - - - Belongs to the UPF0398 family
HOCMNKEB_01527 3.39e-67 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HOCMNKEB_01528 6.16e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HOCMNKEB_01529 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HOCMNKEB_01530 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
HOCMNKEB_01531 3.69e-27 XK27_11680 - - - - - - -
HOCMNKEB_01532 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HOCMNKEB_01533 1.24e-104 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
HOCMNKEB_01534 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOCMNKEB_01535 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOCMNKEB_01536 2.91e-79 - - - L ko:K07497 - ko00000 Integrase core domain protein
HOCMNKEB_01537 1.52e-211 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOCMNKEB_01538 3.32e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HOCMNKEB_01539 6.83e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOCMNKEB_01540 8.25e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
HOCMNKEB_01541 2.43e-145 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HOCMNKEB_01544 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOCMNKEB_01545 2.12e-119 - - - K - - - transcriptional regulator
HOCMNKEB_01546 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
HOCMNKEB_01547 1.89e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HOCMNKEB_01548 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOCMNKEB_01549 7.82e-128 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HOCMNKEB_01550 1.74e-111 ykuL - - S - - - CBS domain
HOCMNKEB_01551 3.26e-172 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HOCMNKEB_01552 1.12e-154 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOCMNKEB_01553 3.08e-128 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOCMNKEB_01554 5.21e-178 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HOCMNKEB_01555 1.81e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HOCMNKEB_01556 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
HOCMNKEB_01557 1.15e-313 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
HOCMNKEB_01558 2.22e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOCMNKEB_01559 4.83e-118 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOCMNKEB_01560 2.31e-148 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
HOCMNKEB_01561 2.94e-206 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
HOCMNKEB_01562 5.6e-45 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
HOCMNKEB_01563 2.45e-141 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HOCMNKEB_01564 1.01e-90 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HOCMNKEB_01565 7.18e-108 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HOCMNKEB_01566 3.67e-62 yhaI - - L - - - Membrane
HOCMNKEB_01567 2.14e-69 - - - S - - - Domain of unknown function (DUF4173)
HOCMNKEB_01568 2.53e-123 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
HOCMNKEB_01569 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HOCMNKEB_01570 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HOCMNKEB_01571 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HOCMNKEB_01572 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
HOCMNKEB_01573 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HOCMNKEB_01574 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HOCMNKEB_01575 8.49e-205 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HOCMNKEB_01576 2.77e-224 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HOCMNKEB_01577 3.37e-176 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
HOCMNKEB_01578 4.48e-170 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HOCMNKEB_01579 3.69e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
HOCMNKEB_01580 0.0 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCMNKEB_01581 0.0 - - - F - - - NUDIX domain
HOCMNKEB_01582 7.28e-268 - - - EGP - - - Transmembrane secretion effector
HOCMNKEB_01583 1.1e-186 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
HOCMNKEB_01584 1.71e-210 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HOCMNKEB_01585 5.2e-113 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HOCMNKEB_01586 2.46e-81 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
HOCMNKEB_01587 4.63e-81 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
HOCMNKEB_01588 7.56e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOCMNKEB_01589 1.25e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
HOCMNKEB_01590 5.97e-267 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HOCMNKEB_01591 5.95e-202 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
HOCMNKEB_01592 1.55e-122 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HOCMNKEB_01593 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_01594 2.29e-187 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HOCMNKEB_01595 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOCMNKEB_01596 4.58e-15 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
HOCMNKEB_01597 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HOCMNKEB_01598 8.24e-309 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
HOCMNKEB_01599 1.5e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
HOCMNKEB_01600 6.87e-120 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HOCMNKEB_01601 2.69e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCMNKEB_01602 0.0 covS - - T - - - Histidine kinase
HOCMNKEB_01603 1.46e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOCMNKEB_01604 3.15e-277 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
HOCMNKEB_01605 5.34e-214 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HOCMNKEB_01606 5.89e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HOCMNKEB_01607 2.78e-115 yrdC - - Q - - - isochorismatase
HOCMNKEB_01608 4.86e-110 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HOCMNKEB_01609 5.16e-72 - - - L ko:K07497 - ko00000 transposition
HOCMNKEB_01610 1.26e-30 - - - L - - - Transposase
HOCMNKEB_01611 2.68e-44 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_01612 1.5e-30 XK27_08085 - - - - - - -
HOCMNKEB_01613 1.5e-119 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
HOCMNKEB_01614 2.04e-17 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
HOCMNKEB_01615 2.41e-181 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
HOCMNKEB_01616 1.2e-158 - - - S - - - tigr01906
HOCMNKEB_01617 6.89e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HOCMNKEB_01618 7.79e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HOCMNKEB_01619 3.27e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HOCMNKEB_01622 3.31e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOCMNKEB_01623 4.07e-144 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HOCMNKEB_01624 1.92e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOCMNKEB_01625 5.91e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
HOCMNKEB_01626 1.28e-131 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
HOCMNKEB_01627 1.15e-189 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOCMNKEB_01628 9.04e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HOCMNKEB_01629 2.02e-92 mesH - - S - - - GtrA-like protein
HOCMNKEB_01630 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOCMNKEB_01631 8.49e-217 ybbR - - S - - - Protein conserved in bacteria
HOCMNKEB_01632 1.91e-159 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOCMNKEB_01633 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
HOCMNKEB_01634 1.02e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HOCMNKEB_01635 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOCMNKEB_01636 4.3e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
HOCMNKEB_01637 1.38e-18 MA20_06245 - - S - - - yiaA/B two helix domain
HOCMNKEB_01639 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
HOCMNKEB_01640 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HOCMNKEB_01641 6.73e-245 yfmL - - L - - - DEAD DEAH box helicase
HOCMNKEB_01642 5.79e-39 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HOCMNKEB_01643 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HOCMNKEB_01644 5.67e-307 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOCMNKEB_01645 1.85e-82 manO - - S - - - protein conserved in bacteria
HOCMNKEB_01646 2.99e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
HOCMNKEB_01647 3.55e-161 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
HOCMNKEB_01648 6.6e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01649 1.84e-181 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
HOCMNKEB_01650 1.46e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HOCMNKEB_01651 5.45e-315 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
HOCMNKEB_01652 3.62e-100 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
HOCMNKEB_01653 6.67e-120 - - - M - - - Acetyltransferase GNAT Family
HOCMNKEB_01654 2.14e-279 brpA - - K - - - Transcriptional
HOCMNKEB_01655 8.78e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HOCMNKEB_01656 2.28e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HOCMNKEB_01657 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
HOCMNKEB_01658 2.19e-56 ylxQ - - J - - - ribosomal protein
HOCMNKEB_01659 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOCMNKEB_01660 9.81e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOCMNKEB_01661 1.44e-29 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HOCMNKEB_01662 3.33e-35 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 cytokinin biosynthetic process
HOCMNKEB_01664 2.14e-60 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
HOCMNKEB_01665 1.87e-199 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
HOCMNKEB_01666 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOCMNKEB_01667 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HOCMNKEB_01668 4.89e-115 pacL - - P - - - cation transport ATPase
HOCMNKEB_01669 1.76e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HOCMNKEB_01670 5.65e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HOCMNKEB_01671 3.28e-06 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
HOCMNKEB_01672 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOCMNKEB_01673 2.64e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOCMNKEB_01674 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HOCMNKEB_01675 4.33e-62 ylbG - - S - - - UPF0298 protein
HOCMNKEB_01676 3.94e-271 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HOCMNKEB_01677 8.19e-190 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HOCMNKEB_01678 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HOCMNKEB_01679 3.96e-177 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HOCMNKEB_01680 5.36e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HOCMNKEB_01681 6.64e-90 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
HOCMNKEB_01682 2.44e-54 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
HOCMNKEB_01683 9.17e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HOCMNKEB_01684 3.86e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HOCMNKEB_01685 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HOCMNKEB_01686 1.19e-157 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HOCMNKEB_01687 1.18e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOCMNKEB_01694 9.95e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HOCMNKEB_01695 9.03e-141 - - - S - - - Domain of unknown function (DUF1803)
HOCMNKEB_01696 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HOCMNKEB_01697 4.96e-173 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HOCMNKEB_01698 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOCMNKEB_01699 9.23e-246 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HOCMNKEB_01700 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HOCMNKEB_01701 1.77e-150 - - - S - - - Haloacid dehalogenase-like hydrolase
HOCMNKEB_01702 4.99e-180 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
HOCMNKEB_01703 2.67e-96 XK27_02735 - - K - - - Transcriptional regulator, MarR family
HOCMNKEB_01704 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOCMNKEB_01705 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOCMNKEB_01706 1.31e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
HOCMNKEB_01707 3.32e-211 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HOCMNKEB_01708 8.26e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HOCMNKEB_01709 2.6e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOCMNKEB_01710 6.1e-88 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOCMNKEB_01711 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOCMNKEB_01712 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HOCMNKEB_01713 7.25e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOCMNKEB_01714 1.88e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HOCMNKEB_01715 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOCMNKEB_01716 7.2e-162 - - - L ko:K07498 - ko00000 Transposase
HOCMNKEB_01717 1.52e-268 - 4.1.1.15 - E ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HOCMNKEB_01718 3.73e-220 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Psort location CytoplasmicMembrane, score 10.00
HOCMNKEB_01719 1.18e-14 - - - L - - - Transposase
HOCMNKEB_01720 2.31e-162 - - - L ko:K07498 - ko00000 Transposase
HOCMNKEB_01722 0.0 - - - S - - - Protein of unknown function (DUF3114)
HOCMNKEB_01723 1.78e-68 - - - K - - - Acetyltransferase GNAT Family
HOCMNKEB_01724 1.23e-249 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 (ABC) transporter
HOCMNKEB_01725 5.01e-93 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
HOCMNKEB_01726 1.44e-106 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
HOCMNKEB_01727 1.71e-143 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
HOCMNKEB_01728 1.53e-198 tra981A - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
HOCMNKEB_01729 1.78e-51 - - - L ko:K07483 - ko00000 transposase activity
HOCMNKEB_01730 1.89e-312 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HOCMNKEB_01731 8.72e-111 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_01732 3.75e-163 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
HOCMNKEB_01733 5.31e-211 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HOCMNKEB_01734 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HOCMNKEB_01735 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOCMNKEB_01736 3.12e-213 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HOCMNKEB_01738 1.8e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HOCMNKEB_01739 1.48e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOCMNKEB_01740 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HOCMNKEB_01741 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HOCMNKEB_01742 2.76e-51 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
HOCMNKEB_01743 1.13e-37 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
HOCMNKEB_01744 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HOCMNKEB_01745 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HOCMNKEB_01746 2.07e-172 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOCMNKEB_01747 3.89e-84 WQ51_03320 - - S - - - cog cog4835
HOCMNKEB_01748 2.26e-117 - - - S - - - EDD domain protein, DegV family
HOCMNKEB_01749 4.46e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOCMNKEB_01750 6.49e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOCMNKEB_01751 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
HOCMNKEB_01752 3.97e-28 - - - S - - - Short repeat of unknown function (DUF308)
HOCMNKEB_01753 5.3e-100 - - - F - - - AdP-ribose pyrophosphatase
HOCMNKEB_01754 1.87e-271 nadR - - H - - - adenylyltransferase
HOCMNKEB_01755 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HOCMNKEB_01756 3.88e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOCMNKEB_01757 4.4e-101 - - - K - - - DNA-binding transcription factor activity
HOCMNKEB_01758 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
HOCMNKEB_01759 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
HOCMNKEB_01760 5.34e-57 - - - K - - - Acetyltransferase (GNAT) family
HOCMNKEB_01761 1.86e-157 sptS - - T - - - Histidine kinase
HOCMNKEB_01762 1.38e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HOCMNKEB_01763 6.76e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOCMNKEB_01764 2.76e-205 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
HOCMNKEB_01765 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
HOCMNKEB_01766 2.67e-212 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
HOCMNKEB_01767 9.15e-90 sip - - M - - - LysM domain protein
HOCMNKEB_01768 4.56e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HOCMNKEB_01772 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOCMNKEB_01773 2.54e-211 - - - K - - - transcriptional regulator (lysR family)
HOCMNKEB_01774 3.31e-238 coiA - - S ko:K06198 - ko00000 Competence protein
HOCMNKEB_01775 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HOCMNKEB_01776 1.38e-163 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
HOCMNKEB_01777 9.95e-225 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
HOCMNKEB_01778 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOCMNKEB_01779 1.67e-29 - - - M - - - GBS Bsp-like repeat
HOCMNKEB_01780 1.85e-241 - - - M - - - GBS Bsp-like repeat
HOCMNKEB_01781 9.52e-45 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
HOCMNKEB_01782 5.29e-39 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
HOCMNKEB_01783 6.4e-69 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
HOCMNKEB_01784 1.29e-186 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HOCMNKEB_01785 5.66e-80 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
HOCMNKEB_01786 1.14e-185 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
HOCMNKEB_01787 1.12e-242 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOCMNKEB_01788 4.21e-285 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOCMNKEB_01789 2.56e-164 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HOCMNKEB_01790 1.31e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HOCMNKEB_01791 6.7e-189 icaB - - G - - - deacetylase
HOCMNKEB_01792 7.29e-304 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HOCMNKEB_01793 1.5e-197 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOCMNKEB_01794 2.56e-193 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
HOCMNKEB_01796 2.62e-17 coiA - - S ko:K06198 - ko00000 Competence protein
HOCMNKEB_01797 2.66e-64 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HOCMNKEB_01798 3.96e-73 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOCMNKEB_01799 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOCMNKEB_01800 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOCMNKEB_01801 6.05e-158 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HOCMNKEB_01802 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
HOCMNKEB_01803 1.05e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOCMNKEB_01804 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOCMNKEB_01805 9.48e-204 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOCMNKEB_01806 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOCMNKEB_01807 6.23e-97 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HOCMNKEB_01808 3.51e-293 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HOCMNKEB_01809 7.86e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOCMNKEB_01810 6.58e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOCMNKEB_01811 5.91e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOCMNKEB_01812 6.71e-208 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
HOCMNKEB_01813 8.56e-179 yaaT - - S - - - stage 0 sporulation protein
HOCMNKEB_01814 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
HOCMNKEB_01815 1.46e-205 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOCMNKEB_01816 1.62e-296 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
HOCMNKEB_01817 3.27e-71 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HOCMNKEB_01818 2.28e-140 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
HOCMNKEB_01819 3.07e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HOCMNKEB_01820 7.89e-144 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HOCMNKEB_01821 2.9e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOCMNKEB_01822 4.34e-73 - - - - - - - -
HOCMNKEB_01823 1.66e-35 - - - - - - - -
HOCMNKEB_01824 4.58e-82 - - - - - - - -
HOCMNKEB_01825 1.06e-40 - - - S - - - membrane
HOCMNKEB_01826 2.48e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HOCMNKEB_01827 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HOCMNKEB_01828 1.42e-52 ynzC - - S - - - UPF0291 protein
HOCMNKEB_01829 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
HOCMNKEB_01831 3.72e-29 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01832 1.22e-92 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01833 4.04e-153 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
HOCMNKEB_01834 3.05e-99 - 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 PTS glucose transporter subunit IIA
HOCMNKEB_01835 1.5e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOCMNKEB_01840 1.36e-215 lysR - - K - - - transcriptional regulator (lysR family)
HOCMNKEB_01841 1.4e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOCMNKEB_01842 3.6e-210 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HOCMNKEB_01843 6.68e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOCMNKEB_01844 2.87e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
HOCMNKEB_01845 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HOCMNKEB_01846 1.12e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
HOCMNKEB_01847 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
HOCMNKEB_01848 4.44e-173 - - - S - - - Putative SAM-dependent methyltransferase
HOCMNKEB_01849 1.46e-46 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOCMNKEB_01850 1.1e-46 - - - V - - - efflux transmembrane transporter activity
HOCMNKEB_01851 1.07e-44 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
HOCMNKEB_01852 4.02e-38 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
HOCMNKEB_01853 4e-100 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOCMNKEB_01854 7.29e-70 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOCMNKEB_01855 1.25e-139 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_01856 1.37e-140 - - - L ko:K07485 - ko00000 Transposase
HOCMNKEB_01857 1.25e-23 - - - L - - - Integrase core domain
HOCMNKEB_01858 1.91e-222 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HOCMNKEB_01862 3.15e-28 - - - L - - - Transposase
HOCMNKEB_01863 5.46e-16 - - - - - - - -
HOCMNKEB_01865 2.65e-192 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_01866 5.52e-194 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_01867 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
HOCMNKEB_01868 1.18e-252 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOCMNKEB_01869 1.03e-163 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOCMNKEB_01870 2.59e-294 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
HOCMNKEB_01871 4.15e-170 rr02 - - KT - - - response regulator
HOCMNKEB_01872 7.99e-280 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HOCMNKEB_01873 2.86e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HOCMNKEB_01874 1.79e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HOCMNKEB_01875 3.36e-251 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HOCMNKEB_01876 1.88e-39 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
HOCMNKEB_01878 1.5e-182 - - - F - - - Phosphorylase superfamily
HOCMNKEB_01879 3.61e-146 - - - S - - - VIT family
HOCMNKEB_01880 6.11e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HOCMNKEB_01881 2.79e-275 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HOCMNKEB_01882 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
HOCMNKEB_01883 2.16e-57 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HOCMNKEB_01884 5.88e-315 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOCMNKEB_01885 1.33e-135 - - - J ko:K09962 - ko00000 protein conserved in bacteria
HOCMNKEB_01886 3.89e-187 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HOCMNKEB_01887 5.37e-221 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HOCMNKEB_01888 1.23e-230 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
HOCMNKEB_01889 2.64e-243 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HOCMNKEB_01890 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOCMNKEB_01891 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
HOCMNKEB_01892 1.47e-41 - - - - - - - -
HOCMNKEB_01893 1.22e-150 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOCMNKEB_01895 3.42e-35 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
HOCMNKEB_01896 9.46e-80 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
HOCMNKEB_01897 1.65e-241 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HOCMNKEB_01898 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HOCMNKEB_01899 5.47e-29 - - - - - - - -
HOCMNKEB_01900 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOCMNKEB_01901 1.54e-75 - - - S - - - hydrolase activity, acting on ester bonds
HOCMNKEB_01902 4.53e-91 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOCMNKEB_01903 7.88e-210 - - - S - - - Protein of unknown function (DUF3114)
HOCMNKEB_01904 9.03e-29 - - - S - - - Protein of unknown function (DUF3114)
HOCMNKEB_01905 1.01e-151 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HOCMNKEB_01906 3.81e-35 - - - K - - - hmm pf08876
HOCMNKEB_01907 2.92e-296 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HOCMNKEB_01908 3.13e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
HOCMNKEB_01909 3.63e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOCMNKEB_01910 7.02e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOCMNKEB_01911 2.97e-30 - - - - - - - -
HOCMNKEB_01912 2.97e-286 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOCMNKEB_01913 6.75e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HOCMNKEB_01914 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HOCMNKEB_01915 3.53e-227 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
HOCMNKEB_01916 5.22e-41 - - - S - - - Domain of unknown function (DUF1912)
HOCMNKEB_01917 1.1e-20 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
HOCMNKEB_01918 1.49e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOCMNKEB_01919 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOCMNKEB_01920 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOCMNKEB_01921 4.29e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HOCMNKEB_01922 3.44e-22 - - - S - - - Protein of unknown function (DUF2969)
HOCMNKEB_01925 1.18e-267 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
HOCMNKEB_01928 9.86e-38 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
HOCMNKEB_01929 5.3e-41 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
HOCMNKEB_01930 2.39e-93 - - - M - - - Pfam SNARE associated Golgi protein
HOCMNKEB_01931 6.61e-296 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
HOCMNKEB_01932 1.74e-11 - - - S - - - oxidoreductase
HOCMNKEB_01933 1.83e-74 - - - S - - - oxidoreductase
HOCMNKEB_01934 2.73e-84 - - - S - - - oxidoreductase
HOCMNKEB_01935 1.29e-64 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
HOCMNKEB_01936 7.82e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HOCMNKEB_01937 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HOCMNKEB_01938 3.17e-231 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOCMNKEB_01939 1.15e-47 ykuJ - - S - - - protein conserved in bacteria
HOCMNKEB_01940 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HOCMNKEB_01941 7.69e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
HOCMNKEB_01942 4.28e-102 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
HOCMNKEB_01943 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HOCMNKEB_01944 1.76e-66 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HOCMNKEB_01945 9.87e-12 - - - - - - - -
HOCMNKEB_01946 1.27e-135 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HOCMNKEB_01947 7.29e-61 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
HOCMNKEB_01948 2.87e-47 yugF - - I - - - carboxylic ester hydrolase activity
HOCMNKEB_01949 5.04e-29 - - - I - - - Alpha/beta hydrolase family
HOCMNKEB_01950 9.86e-202 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOCMNKEB_01951 2.91e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOCMNKEB_01952 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
HOCMNKEB_01953 5.31e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOCMNKEB_01954 6e-83 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HOCMNKEB_01955 1.17e-67 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HOCMNKEB_01956 2.18e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOCMNKEB_01957 1.16e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HOCMNKEB_01958 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOCMNKEB_01959 1.16e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HOCMNKEB_01960 2.68e-137 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOCMNKEB_01961 2.94e-281 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
HOCMNKEB_01962 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HOCMNKEB_01963 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HOCMNKEB_01964 5.69e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOCMNKEB_01965 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOCMNKEB_01966 1.08e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
HOCMNKEB_01967 9.95e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
HOCMNKEB_01968 1.34e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
HOCMNKEB_01969 2.03e-35 XK27_07735 - - S - - - YjbR
HOCMNKEB_01970 6.38e-130 yyaQ - - V - - - Protein conserved in bacteria
HOCMNKEB_01971 1.03e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HOCMNKEB_01972 8.46e-101 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HOCMNKEB_01973 1.75e-314 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)