ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
JIOHCKLC_00017 2.35e-180 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
JIOHCKLC_00018 4.35e-116 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JIOHCKLC_00019 2.35e-185 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
JIOHCKLC_00020 2.75e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JIOHCKLC_00021 1.06e-278 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
JIOHCKLC_00022 5.05e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
JIOHCKLC_00023 2.58e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JIOHCKLC_00024 3.89e-46 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
JIOHCKLC_00025 1.75e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
JIOHCKLC_00026 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JIOHCKLC_00027 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JIOHCKLC_00028 4.91e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
JIOHCKLC_00029 6.85e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JIOHCKLC_00030 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
JIOHCKLC_00031 9.49e-103 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_00032 2.17e-68 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_00033 2.32e-43 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00034 3.46e-204 - - - S - - - CHAP domain
JIOHCKLC_00035 8.2e-306 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
JIOHCKLC_00036 2.66e-99 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JIOHCKLC_00037 1.03e-261 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JIOHCKLC_00038 1.69e-181 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
JIOHCKLC_00039 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JIOHCKLC_00040 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JIOHCKLC_00041 1.36e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
JIOHCKLC_00042 5.42e-75 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
JIOHCKLC_00043 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JIOHCKLC_00044 1.06e-43 - - - S - - - Protein of unknown function (DUF3021)
JIOHCKLC_00045 2.17e-81 - - - KT - - - phosphorelay signal transduction system
JIOHCKLC_00047 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JIOHCKLC_00049 4.38e-134 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JIOHCKLC_00050 1.89e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
JIOHCKLC_00051 2.06e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
JIOHCKLC_00052 4.62e-255 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JIOHCKLC_00053 1.27e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
JIOHCKLC_00054 7.2e-27 - - - V - - - D-alanyl-D-alanine carboxypeptidase
JIOHCKLC_00055 4.5e-150 pppA 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
JIOHCKLC_00056 5.82e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
JIOHCKLC_00057 7.8e-38 yqgQ - - S - - - protein conserved in bacteria
JIOHCKLC_00058 1.76e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
JIOHCKLC_00059 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
JIOHCKLC_00060 2.68e-12 - - - S - - - Protein of unknown function (DUF3165)
JIOHCKLC_00061 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JIOHCKLC_00062 3.84e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JIOHCKLC_00063 1.94e-235 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JIOHCKLC_00064 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JIOHCKLC_00065 2.64e-303 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JIOHCKLC_00066 9.77e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JIOHCKLC_00067 1.79e-125 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
JIOHCKLC_00068 1.8e-46 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
JIOHCKLC_00069 4.13e-185 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
JIOHCKLC_00070 2.95e-186 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
JIOHCKLC_00071 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JIOHCKLC_00072 1.93e-12 - - - - - - - -
JIOHCKLC_00073 4.66e-296 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
JIOHCKLC_00074 1.39e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
JIOHCKLC_00075 5.61e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JIOHCKLC_00076 2.51e-236 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
JIOHCKLC_00077 7.83e-197 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
JIOHCKLC_00078 1.3e-239 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JIOHCKLC_00079 1.16e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
JIOHCKLC_00080 5.57e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JIOHCKLC_00081 3.18e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JIOHCKLC_00082 1.2e-140 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JIOHCKLC_00083 1.45e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JIOHCKLC_00084 4.29e-228 - - - S - - - 37-kD nucleoid-associated bacterial protein
JIOHCKLC_00085 1.1e-128 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
JIOHCKLC_00086 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00087 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00088 3.08e-14 - - - S - - - D-Ala-teichoic acid biosynthesis protein
JIOHCKLC_00089 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JIOHCKLC_00090 2.07e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
JIOHCKLC_00091 4.98e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JIOHCKLC_00092 1.09e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JIOHCKLC_00093 1.4e-44 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00094 5.03e-43 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_00095 9.69e-72 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_00096 3.19e-25 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_00097 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
JIOHCKLC_00098 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
JIOHCKLC_00102 1.88e-69 - - - S - - - Virulence-associated protein E
JIOHCKLC_00103 1.18e-164 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
JIOHCKLC_00104 1.9e-30 - - - - - - - -
JIOHCKLC_00109 1.52e-27 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
JIOHCKLC_00110 1.55e-24 - - - K - - - transcriptional
JIOHCKLC_00111 1.57e-280 - - - L - - - Belongs to the 'phage' integrase family
JIOHCKLC_00113 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JIOHCKLC_00114 2.2e-212 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
JIOHCKLC_00115 2.56e-166 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
JIOHCKLC_00116 2.67e-184 - - - - - - - -
JIOHCKLC_00117 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
JIOHCKLC_00118 0.0 - 2.4.1.52 GT4 M ko:K00712,ko:K21011 ko02025,map02025 ko00000,ko00001,ko01000,ko01003 Domain of unknown function (DUF3492)
JIOHCKLC_00119 1.15e-244 - - - M ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
JIOHCKLC_00120 6.04e-272 - - - M ko:K06330 - ko00000 CotH kinase protein
JIOHCKLC_00121 2.46e-68 - - - G - - - Domain of unknown function (DUF4832)
JIOHCKLC_00122 3.55e-12 - - - G - - - Domain of unknown function (DUF4832)
JIOHCKLC_00123 6.05e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
JIOHCKLC_00125 3.41e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JIOHCKLC_00126 4.09e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
JIOHCKLC_00127 6.78e-177 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
JIOHCKLC_00128 4.11e-142 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
JIOHCKLC_00129 7.97e-157 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00130 2.31e-192 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
JIOHCKLC_00131 5.43e-180 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00132 2.49e-166 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JIOHCKLC_00133 9.32e-316 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
JIOHCKLC_00134 1.77e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
JIOHCKLC_00135 2.58e-294 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
JIOHCKLC_00136 5.66e-189 XK27_00835 - - S - - - hydrolases of the HAD superfamily
JIOHCKLC_00137 9.96e-69 XK27_00115 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
JIOHCKLC_00138 1.19e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
JIOHCKLC_00139 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
JIOHCKLC_00140 1.38e-174 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
JIOHCKLC_00141 2.04e-229 - - - S - - - Calcineurin-like phosphoesterase
JIOHCKLC_00142 2.13e-263 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JIOHCKLC_00143 6.25e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JIOHCKLC_00144 7.31e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
JIOHCKLC_00145 1.99e-209 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JIOHCKLC_00146 3.52e-120 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JIOHCKLC_00147 4.97e-231 XK27_05220 - - S - - - permease
JIOHCKLC_00148 1.34e-285 XK27_05225 - - G - - - COG0457 FOG TPR repeat
JIOHCKLC_00149 1.95e-127 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
JIOHCKLC_00150 5.04e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
JIOHCKLC_00151 1.12e-119 ebsA - - S - - - Family of unknown function (DUF5322)
JIOHCKLC_00152 6.79e-48 XK27_09115 - - M - - - LysM domain
JIOHCKLC_00153 8.33e-156 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
JIOHCKLC_00154 3.15e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JIOHCKLC_00155 5.79e-39 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
JIOHCKLC_00156 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JIOHCKLC_00157 1.61e-55 - - - L ko:K07491 - ko00000 Transposase
JIOHCKLC_00158 1.39e-33 - - - L ko:K07491 - ko00000 Transposase
JIOHCKLC_00159 5.58e-62 XK27_03610 - - K - - - Gnat family
JIOHCKLC_00160 2.78e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
JIOHCKLC_00161 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
JIOHCKLC_00162 1.32e-143 ung2 - - L - - - Uracil-DNA glycosylase
JIOHCKLC_00165 7.14e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JIOHCKLC_00166 1.28e-298 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
JIOHCKLC_00167 1.19e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JIOHCKLC_00168 6.39e-151 clcA2 - - P - - - chloride
JIOHCKLC_00169 3.81e-13 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
JIOHCKLC_00170 4.28e-105 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
JIOHCKLC_00171 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
JIOHCKLC_00172 1.51e-314 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
JIOHCKLC_00173 2.22e-173 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
JIOHCKLC_00174 2.31e-139 capA - - M - - - biosynthesis protein
JIOHCKLC_00175 1.23e-151 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
JIOHCKLC_00176 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JIOHCKLC_00177 6.25e-74 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
JIOHCKLC_00178 1.13e-100 lspL 5.1.3.6 - M ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 epimerase dehydratase
JIOHCKLC_00179 2.96e-45 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JIOHCKLC_00180 9.79e-254 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
JIOHCKLC_00181 3.64e-191 - - - M - - - Glycosyl transferases group 1
JIOHCKLC_00182 2.2e-47 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
JIOHCKLC_00183 1.16e-38 - - - M - - - Psort location Cytoplasmic, score 8.87
JIOHCKLC_00184 1.12e-43 cps4F - - M - - - Glycosyl transferases group 1
JIOHCKLC_00185 9.97e-129 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JIOHCKLC_00186 4.44e-74 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JIOHCKLC_00187 1.58e-22 rfbF - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
JIOHCKLC_00188 3.19e-76 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
JIOHCKLC_00189 1.21e-25 - - - - - - - -
JIOHCKLC_00190 8.49e-29 - - - M - - - Glycosyltransferase WbsX
JIOHCKLC_00191 1.09e-101 - - - M - - - Glycosyl transferase, family 2
JIOHCKLC_00193 1.95e-44 - - - L - - - Transposase DDE domain
JIOHCKLC_00194 8.67e-202 - - - G - - - Phosphodiester glycosidase
JIOHCKLC_00195 1.19e-185 - - - K - - - Cell envelope-related transcriptional attenuator domain
JIOHCKLC_00196 3.42e-119 - - - V - - - VanZ like family
JIOHCKLC_00197 3.67e-215 - - - L ko:K07481 - ko00000 transposase, IS4 family
JIOHCKLC_00198 6.5e-306 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
JIOHCKLC_00199 1.02e-43 - - - S - - - Glycosyltransferase like family 2
JIOHCKLC_00200 1.2e-91 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
JIOHCKLC_00201 5.99e-50 - - - L ko:K07483 - ko00000 transposase helper protein for IS981
JIOHCKLC_00202 1e-40 - - - M - - - transferase activity, transferring glycosyl groups
JIOHCKLC_00203 3.03e-09 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
JIOHCKLC_00204 3.49e-149 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
JIOHCKLC_00205 1.95e-48 - - - G - - - alpha-ribazole phosphatase activity
JIOHCKLC_00206 5.13e-39 - - - G - - - Belongs to the phosphoglycerate mutase family
JIOHCKLC_00207 1.68e-254 XK27_12525 - - S - - - hmm pf01594
JIOHCKLC_00208 2.27e-37 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
JIOHCKLC_00209 2.14e-123 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
JIOHCKLC_00210 1.15e-56 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
JIOHCKLC_00211 3.34e-52 - - - S - - - granule-associated protein
JIOHCKLC_00212 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
JIOHCKLC_00213 2.96e-20 - - - E - - - Lysophospholipase L1 and related esterases
JIOHCKLC_00214 1.35e-102 - - - E - - - GDSL-like protein
JIOHCKLC_00215 1.3e-201 - - - S - - - Phospholipase, patatin family
JIOHCKLC_00216 3.83e-277 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JIOHCKLC_00217 6.69e-162 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JIOHCKLC_00218 2.94e-300 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JIOHCKLC_00219 1.27e-77 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
JIOHCKLC_00220 4.19e-53 - - - P - - - membrane protein (DUF2207)
JIOHCKLC_00221 1.07e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
JIOHCKLC_00222 3.38e-232 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JIOHCKLC_00223 4.28e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JIOHCKLC_00224 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
JIOHCKLC_00225 1.17e-26 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
JIOHCKLC_00226 1.43e-97 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
JIOHCKLC_00227 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
JIOHCKLC_00228 2.13e-44 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
JIOHCKLC_00229 2.64e-159 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00230 7.09e-84 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00231 5.89e-70 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00232 4.24e-111 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00233 4.39e-42 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00234 3.04e-200 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
JIOHCKLC_00235 7.41e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
JIOHCKLC_00236 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
JIOHCKLC_00237 1.83e-156 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JIOHCKLC_00238 4.79e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
JIOHCKLC_00240 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
JIOHCKLC_00241 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JIOHCKLC_00244 2.63e-240 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
JIOHCKLC_00245 1.88e-249 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
JIOHCKLC_00246 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
JIOHCKLC_00247 1.1e-147 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
JIOHCKLC_00248 1.24e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JIOHCKLC_00249 5.27e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JIOHCKLC_00250 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
JIOHCKLC_00251 4.63e-201 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
JIOHCKLC_00252 2.07e-202 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
JIOHCKLC_00253 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
JIOHCKLC_00254 8.38e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
JIOHCKLC_00255 1.99e-58 yktA - - S - - - Belongs to the UPF0223 family
JIOHCKLC_00256 7.52e-95 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JIOHCKLC_00257 1.28e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
JIOHCKLC_00258 5.24e-195 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JIOHCKLC_00259 5.47e-61 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
JIOHCKLC_00260 1.02e-124 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
JIOHCKLC_00261 3.31e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
JIOHCKLC_00262 1.48e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JIOHCKLC_00263 5.48e-79 - - - S - - - haloacid dehalogenase-like hydrolase
JIOHCKLC_00264 6.24e-78 - - - Q - - - phosphatase activity
JIOHCKLC_00265 2.95e-307 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
JIOHCKLC_00266 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
JIOHCKLC_00267 7.07e-307 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
JIOHCKLC_00268 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JIOHCKLC_00269 4.64e-135 yfiF3 - - K - - - sequence-specific DNA binding
JIOHCKLC_00270 1.56e-45 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
JIOHCKLC_00271 4.78e-142 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
JIOHCKLC_00272 1.07e-09 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
JIOHCKLC_00273 2.39e-86 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00274 1.06e-170 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
JIOHCKLC_00275 3.65e-134 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
JIOHCKLC_00276 0.0 dtpT - - E ko:K03305 - ko00000 transporter
JIOHCKLC_00278 2.1e-78 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
JIOHCKLC_00279 4.34e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JIOHCKLC_00280 5.04e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JIOHCKLC_00281 4.55e-95 - - - S - - - Psort location Cytoplasmic, score
JIOHCKLC_00282 7.98e-18 - - - S - - - Psort location Cytoplasmic, score
JIOHCKLC_00283 6.42e-262 csm5 - - L ko:K19140 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm5 family
JIOHCKLC_00284 2.45e-214 csm4 - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
JIOHCKLC_00285 1.62e-150 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
JIOHCKLC_00286 7.5e-83 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
JIOHCKLC_00287 0.0 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
JIOHCKLC_00288 7.74e-174 - - - S - - - Pfam:DUF2276
JIOHCKLC_00289 2.91e-72 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JIOHCKLC_00290 1.56e-230 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JIOHCKLC_00291 1.17e-223 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JIOHCKLC_00292 8.38e-190 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JIOHCKLC_00293 4.28e-125 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
JIOHCKLC_00294 9.76e-153 - - - S - - - TraX protein
JIOHCKLC_00296 5.51e-38 - 3.4.13.21 - I ko:K05995,ko:K06888 - ko00000,ko01000,ko01002 Protein conserved in bacteria
JIOHCKLC_00297 1.01e-115 - - - F - - - Belongs to the Nudix hydrolase family
JIOHCKLC_00298 1.86e-243 - - - - - - - -
JIOHCKLC_00299 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
JIOHCKLC_00301 2.17e-51 dinF - - V - - - Mate efflux family protein
JIOHCKLC_00302 1.34e-92 dinF - - V - - - Mate efflux family protein
JIOHCKLC_00303 9.2e-25 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
JIOHCKLC_00304 6.66e-19 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
JIOHCKLC_00305 6.95e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
JIOHCKLC_00306 9.83e-187 - - - F - - - Phosphorylase superfamily
JIOHCKLC_00309 2.84e-102 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
JIOHCKLC_00310 3.95e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
JIOHCKLC_00311 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
JIOHCKLC_00312 2.78e-250 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
JIOHCKLC_00313 2.72e-184 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
JIOHCKLC_00314 2.11e-69 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
JIOHCKLC_00315 3.17e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
JIOHCKLC_00316 1.09e-126 - - - K - - - Transcriptional regulator, TetR family
JIOHCKLC_00317 9.28e-15 - - - - - - - -
JIOHCKLC_00318 3.51e-146 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
JIOHCKLC_00319 4e-141 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00320 1.34e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
JIOHCKLC_00321 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
JIOHCKLC_00322 9.01e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
JIOHCKLC_00323 3.15e-175 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
JIOHCKLC_00324 3.68e-271 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
JIOHCKLC_00327 5.91e-199 - - - K - - - Transcriptional activator, Rgg GadR MutR family
JIOHCKLC_00328 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JIOHCKLC_00329 1.01e-24 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
JIOHCKLC_00330 8.3e-67 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
JIOHCKLC_00331 4.95e-63 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JIOHCKLC_00332 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JIOHCKLC_00333 3.66e-28 XK27_05470 - - E - - - Methionine synthase
JIOHCKLC_00334 6.2e-195 XK27_05470 - - E - - - Methionine synthase
JIOHCKLC_00335 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JIOHCKLC_00336 0.0 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
JIOHCKLC_00337 2.93e-157 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JIOHCKLC_00338 7.22e-199 - - - S - - - TraX protein
JIOHCKLC_00339 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JIOHCKLC_00340 9.91e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
JIOHCKLC_00341 1.79e-215 - - - GK - - - ROK family
JIOHCKLC_00342 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JIOHCKLC_00343 1.46e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JIOHCKLC_00344 2.14e-164 - - - K - - - DNA-binding helix-turn-helix protein
JIOHCKLC_00345 1.3e-116 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
JIOHCKLC_00346 8e-113 niaX - - - ko:K16788 - ko00000,ko02000 -
JIOHCKLC_00347 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JIOHCKLC_00348 9e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JIOHCKLC_00349 3.67e-162 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
JIOHCKLC_00350 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
JIOHCKLC_00351 9.23e-59 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
JIOHCKLC_00352 1.07e-133 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
JIOHCKLC_00353 7.7e-42 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
JIOHCKLC_00354 1.53e-179 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JIOHCKLC_00355 1.04e-48 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JIOHCKLC_00356 1.35e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
JIOHCKLC_00357 5.28e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00358 3.92e-134 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00359 4.47e-76 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
JIOHCKLC_00360 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JIOHCKLC_00361 2.18e-214 cpsY - - K - - - Transcriptional regulator
JIOHCKLC_00362 4.7e-107 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_00363 1.86e-153 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
JIOHCKLC_00364 4.73e-221 yeiH - - S - - - Membrane
JIOHCKLC_00366 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
JIOHCKLC_00367 1.69e-128 XK27_10720 - - D - - - peptidase activity
JIOHCKLC_00368 8.54e-98 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
JIOHCKLC_00369 1.33e-07 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
JIOHCKLC_00370 9.82e-203 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
JIOHCKLC_00371 1.1e-143 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
JIOHCKLC_00372 3.85e-72 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
JIOHCKLC_00373 6.67e-123 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
JIOHCKLC_00374 8.39e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
JIOHCKLC_00375 1.8e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
JIOHCKLC_00376 2.37e-249 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
JIOHCKLC_00377 0.0 copB 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
JIOHCKLC_00378 8.77e-56 cspA - - K ko:K03704 - ko00000,ko03000 Cold-Shock Protein
JIOHCKLC_00379 2.63e-44 - - - K - - - Cold shock protein domain
JIOHCKLC_00380 2.45e-211 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
JIOHCKLC_00381 1.2e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
JIOHCKLC_00382 3.04e-232 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
JIOHCKLC_00383 2.08e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
JIOHCKLC_00384 1.88e-176 yejC - - S - - - cyclic nucleotide-binding protein
JIOHCKLC_00385 1.25e-23 - - - D - - - nuclear chromosome segregation
JIOHCKLC_00386 4.7e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
JIOHCKLC_00387 2.6e-174 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JIOHCKLC_00388 2.87e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
JIOHCKLC_00389 2.15e-158 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JIOHCKLC_00390 1.84e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
JIOHCKLC_00391 1.82e-17 - - - - - - - -
JIOHCKLC_00393 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JIOHCKLC_00394 1.83e-277 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
JIOHCKLC_00395 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
JIOHCKLC_00396 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
JIOHCKLC_00397 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
JIOHCKLC_00398 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
JIOHCKLC_00399 9.61e-247 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
JIOHCKLC_00400 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
JIOHCKLC_00401 6.01e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
JIOHCKLC_00402 6.79e-91 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JIOHCKLC_00403 4.43e-82 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JIOHCKLC_00404 7.07e-40 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JIOHCKLC_00405 1.69e-117 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JIOHCKLC_00406 2.16e-32 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
JIOHCKLC_00407 2.18e-32 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JIOHCKLC_00408 1.86e-135 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
JIOHCKLC_00409 1.01e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
JIOHCKLC_00410 1.98e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
JIOHCKLC_00411 1.21e-209 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00412 1.68e-106 - - - L - - - Helix-turn-helix domain
JIOHCKLC_00413 1.5e-28 - - - L - - - Helix-turn-helix domain
JIOHCKLC_00414 0.0 vpr 3.4.21.96 - O ko:K01361,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
JIOHCKLC_00415 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
JIOHCKLC_00416 2.99e-185 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
JIOHCKLC_00417 1.37e-49 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
JIOHCKLC_00418 1.92e-36 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
JIOHCKLC_00419 7.99e-283 - - - L ko:K07485 - ko00000 Transposase
JIOHCKLC_00420 1.11e-114 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
JIOHCKLC_00421 2.38e-53 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
JIOHCKLC_00422 1.67e-49 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
JIOHCKLC_00423 4.04e-86 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JIOHCKLC_00424 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
JIOHCKLC_00425 6.6e-158 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
JIOHCKLC_00426 5.7e-124 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JIOHCKLC_00427 1.46e-120 - - - S - - - ECF transporter, substrate-specific component
JIOHCKLC_00428 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
JIOHCKLC_00435 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JIOHCKLC_00436 4.87e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
JIOHCKLC_00437 1.99e-48 XK27_02060 - - S - - - Transglycosylase associated protein
JIOHCKLC_00438 1.44e-72 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
JIOHCKLC_00439 1.13e-125 XK27_03570 - - S ko:K19784 - ko00000 reductase
JIOHCKLC_00440 5.74e-41 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00441 4.24e-30 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 carboxypeptidase activity
JIOHCKLC_00442 2.86e-127 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
JIOHCKLC_00444 5e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
JIOHCKLC_00445 1.73e-232 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JIOHCKLC_00446 3.55e-109 - - - S - - - Putative small multi-drug export protein
JIOHCKLC_00447 2.83e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
JIOHCKLC_00448 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
JIOHCKLC_00449 1.71e-193 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
JIOHCKLC_00450 3.96e-40 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
JIOHCKLC_00451 1.38e-295 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
JIOHCKLC_00452 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JIOHCKLC_00453 9.44e-186 - - - S - - - SseB protein N-terminal domain
JIOHCKLC_00454 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
JIOHCKLC_00455 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
JIOHCKLC_00456 2.1e-90 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JIOHCKLC_00459 1.23e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JIOHCKLC_00460 8.14e-120 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
JIOHCKLC_00461 1.1e-199 yitS - - S - - - DegV family
JIOHCKLC_00462 1.22e-42 - - - K - - - helix-turn-helix
JIOHCKLC_00463 4e-234 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JIOHCKLC_00464 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JIOHCKLC_00465 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
JIOHCKLC_00466 5.75e-267 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JIOHCKLC_00467 2.38e-223 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JIOHCKLC_00468 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JIOHCKLC_00469 1.12e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
JIOHCKLC_00470 1.75e-208 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JIOHCKLC_00471 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
JIOHCKLC_00473 5.73e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JIOHCKLC_00474 2.5e-278 - - - P - - - chloride
JIOHCKLC_00475 1.27e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
JIOHCKLC_00476 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
JIOHCKLC_00477 1.42e-97 ykuP - - C ko:K03839 - ko00000 Flavodoxin
JIOHCKLC_00479 2.2e-162 XK27_08875 - - O - - - Zinc-dependent metalloprotease
JIOHCKLC_00480 3.72e-194 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
JIOHCKLC_00481 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JIOHCKLC_00482 5.4e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00483 3.93e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
JIOHCKLC_00484 1.68e-229 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
JIOHCKLC_00485 5.6e-17 - - - S - - - Domain of unknown function (DUF4649)
JIOHCKLC_00487 1.43e-35 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
JIOHCKLC_00488 5.28e-34 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
JIOHCKLC_00490 6.86e-11 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
JIOHCKLC_00491 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
JIOHCKLC_00492 1.04e-239 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JIOHCKLC_00493 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
JIOHCKLC_00494 1.99e-194 XK27_00020 - - J - - - Belongs to the SUA5 family
JIOHCKLC_00495 2.76e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JIOHCKLC_00496 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JIOHCKLC_00497 2.72e-56 ysdA - - L - - - Membrane
JIOHCKLC_00498 7.51e-242 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JIOHCKLC_00499 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JIOHCKLC_00500 3.05e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JIOHCKLC_00501 3.83e-229 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
JIOHCKLC_00503 1.54e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JIOHCKLC_00504 2.85e-122 ypmS - - S - - - Protein conserved in bacteria
JIOHCKLC_00505 4.24e-185 ypmR - - E - - - lipolytic protein G-D-S-L family
JIOHCKLC_00506 1.18e-190 WQ51_01275 - - S - - - DegV family
JIOHCKLC_00507 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
JIOHCKLC_00508 1.72e-94 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
JIOHCKLC_00509 2.83e-203 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
JIOHCKLC_00510 8.12e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
JIOHCKLC_00511 1.72e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
JIOHCKLC_00512 9.08e-314 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JIOHCKLC_00515 3.81e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JIOHCKLC_00516 9.02e-163 dnaD - - - ko:K02086 - ko00000 -
JIOHCKLC_00517 5.91e-234 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JIOHCKLC_00518 6.44e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JIOHCKLC_00519 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
JIOHCKLC_00520 4.46e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
JIOHCKLC_00521 4.43e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JIOHCKLC_00522 1.15e-152 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
JIOHCKLC_00523 5.77e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JIOHCKLC_00524 0.0 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
JIOHCKLC_00525 1.48e-65 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
JIOHCKLC_00526 7.31e-81 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JIOHCKLC_00527 8.59e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JIOHCKLC_00528 9.32e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JIOHCKLC_00529 3.32e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JIOHCKLC_00530 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
JIOHCKLC_00531 2.16e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JIOHCKLC_00532 1.98e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JIOHCKLC_00533 5.26e-234 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JIOHCKLC_00534 1.23e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JIOHCKLC_00536 1.5e-30 XK27_08085 - - - - - - -
JIOHCKLC_00537 1.5e-119 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
JIOHCKLC_00538 2.04e-17 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
JIOHCKLC_00539 2.41e-181 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
JIOHCKLC_00540 1.2e-158 - - - S - - - tigr01906
JIOHCKLC_00541 6.89e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JIOHCKLC_00542 5.49e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
JIOHCKLC_00543 3.27e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
JIOHCKLC_00545 3.31e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JIOHCKLC_00546 4.07e-144 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JIOHCKLC_00547 1.92e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JIOHCKLC_00548 5.91e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
JIOHCKLC_00549 1.28e-131 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
JIOHCKLC_00550 1.15e-189 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JIOHCKLC_00551 9.04e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
JIOHCKLC_00552 2.86e-92 mesH - - S - - - GtrA-like protein
JIOHCKLC_00553 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JIOHCKLC_00554 1.47e-217 ybbR - - S - - - Protein conserved in bacteria
JIOHCKLC_00555 1.15e-160 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JIOHCKLC_00556 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
JIOHCKLC_00557 1.02e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
JIOHCKLC_00558 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JIOHCKLC_00559 4.3e-169 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
JIOHCKLC_00560 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
JIOHCKLC_00561 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
JIOHCKLC_00562 6.73e-245 yfmL - - L - - - DEAD DEAH box helicase
JIOHCKLC_00563 5.79e-39 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
JIOHCKLC_00564 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
JIOHCKLC_00565 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JIOHCKLC_00566 3.31e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
JIOHCKLC_00567 7.22e-283 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
JIOHCKLC_00568 4.25e-271 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
JIOHCKLC_00569 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JIOHCKLC_00570 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
JIOHCKLC_00571 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JIOHCKLC_00572 8.44e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JIOHCKLC_00574 2.35e-50 - - - L - - - Transposase (IS116 IS110 IS902 family)
JIOHCKLC_00575 1.1e-36 - - - L - - - Transposase (IS116 IS110 IS902 family)
JIOHCKLC_00576 1.39e-211 ypuA - - S - - - secreted protein
JIOHCKLC_00577 1.88e-67 ywkD - - E ko:K08234 - ko00000 COG0346 LactoylglutaTHIone lyase and related lyases
JIOHCKLC_00578 4.41e-169 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
JIOHCKLC_00579 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JIOHCKLC_00580 2.06e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
JIOHCKLC_00581 0.0 noxE - - P - - - NADH oxidase
JIOHCKLC_00582 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
JIOHCKLC_00583 3.43e-107 - - - S - - - ECF-type riboflavin transporter, S component
JIOHCKLC_00584 4.44e-108 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
JIOHCKLC_00585 4.85e-56 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
JIOHCKLC_00586 1.46e-112 - - - S - - - ECF-type riboflavin transporter, S component
JIOHCKLC_00588 1.03e-304 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JIOHCKLC_00589 2.66e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
JIOHCKLC_00592 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JIOHCKLC_00593 1.07e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JIOHCKLC_00594 1.96e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JIOHCKLC_00595 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
JIOHCKLC_00596 1.69e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JIOHCKLC_00597 6.31e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JIOHCKLC_00598 2.9e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JIOHCKLC_00599 4.37e-119 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
JIOHCKLC_00600 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JIOHCKLC_00601 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JIOHCKLC_00602 1.76e-164 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
JIOHCKLC_00603 1.24e-121 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
JIOHCKLC_00604 3.14e-177 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00605 2.63e-212 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
JIOHCKLC_00606 1.46e-132 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00607 0.0 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
JIOHCKLC_00608 1.2e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
JIOHCKLC_00609 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JIOHCKLC_00610 3.04e-19 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
JIOHCKLC_00611 1.1e-106 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
JIOHCKLC_00612 1.03e-38 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
JIOHCKLC_00613 2.23e-131 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
JIOHCKLC_00615 8.38e-188 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
JIOHCKLC_00616 4.06e-127 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
JIOHCKLC_00617 1.4e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JIOHCKLC_00618 1.2e-245 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
JIOHCKLC_00619 2.48e-171 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
JIOHCKLC_00620 2.94e-203 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00623 3.05e-210 yocS - - S ko:K03453 - ko00000 Transporter
JIOHCKLC_00624 9.95e-108 - - - F - - - cytidine deaminase activity
JIOHCKLC_00625 3.95e-147 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
JIOHCKLC_00626 2.89e-194 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00629 7.82e-128 - - - S ko:K06940 - ko00000 Fe-S-cluster oxidoreductase
JIOHCKLC_00630 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
JIOHCKLC_00631 6.05e-171 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
JIOHCKLC_00632 1.2e-215 - - - T - - - Histidine kinase
JIOHCKLC_00633 2.13e-158 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JIOHCKLC_00634 2.47e-100 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JIOHCKLC_00635 4.96e-86 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
JIOHCKLC_00636 1.48e-153 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
JIOHCKLC_00637 0.0 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
JIOHCKLC_00638 5.51e-239 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JIOHCKLC_00639 4.2e-301 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
JIOHCKLC_00640 2.22e-85 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
JIOHCKLC_00641 3.23e-75 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
JIOHCKLC_00642 5.5e-34 csbD - - K - - - CsbD-like
JIOHCKLC_00643 4.6e-294 yfnA - - E ko:K03294 - ko00000 amino acid
JIOHCKLC_00644 3.47e-142 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
JIOHCKLC_00645 1.37e-192 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
JIOHCKLC_00646 2.96e-100 ywnA_2 - - K - - - Transcriptional regulator
JIOHCKLC_00647 1.07e-202 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
JIOHCKLC_00648 1.19e-294 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JIOHCKLC_00649 2.35e-142 ydgI - - C - - - Nitroreductase
JIOHCKLC_00650 1.33e-136 - - - S - - - Protein of unknown function (DUF1275)
JIOHCKLC_00651 1.23e-06 - - - S - - - Protein of unknown function (DUF1275)
JIOHCKLC_00652 2.73e-204 yvgN - - C - - - reductase
JIOHCKLC_00653 7.53e-229 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
JIOHCKLC_00654 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
JIOHCKLC_00656 1.58e-50 BP1961 - - P - - - nitric oxide dioxygenase activity
JIOHCKLC_00657 1.79e-70 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
JIOHCKLC_00658 4.2e-86 - - - S - - - Signal peptide protein, YSIRK family
JIOHCKLC_00659 8.65e-81 - - - - - - - -
JIOHCKLC_00660 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JIOHCKLC_00661 1.14e-217 - - - - - - - -
JIOHCKLC_00662 1.08e-14 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
JIOHCKLC_00664 4.88e-140 - - - E - - - LysE type translocator
JIOHCKLC_00665 6.23e-11 - - - - - - - -
JIOHCKLC_00666 1.96e-12 - - - - - - - -
JIOHCKLC_00667 0.0 - - - M - - - family 8
JIOHCKLC_00669 9.49e-223 hrtB - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
JIOHCKLC_00670 3.81e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00671 1.31e-195 - - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MatE
JIOHCKLC_00672 2.93e-10 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
JIOHCKLC_00673 9.95e-138 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
JIOHCKLC_00674 6.25e-227 - - - EGP - - - Major Facilitator Superfamily
JIOHCKLC_00675 0.0 - - - I - - - radical SAM domain protein
JIOHCKLC_00677 7.24e-205 - - - K - - - Transcriptional activator, Rgg GadR MutR family
JIOHCKLC_00678 1.88e-194 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00679 8.81e-114 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_00681 2.36e-110 - - - - - - - -
JIOHCKLC_00682 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
JIOHCKLC_00683 2.27e-293 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JIOHCKLC_00684 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
JIOHCKLC_00685 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
JIOHCKLC_00686 2.8e-256 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
JIOHCKLC_00687 6.03e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
JIOHCKLC_00688 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
JIOHCKLC_00689 1.15e-282 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JIOHCKLC_00690 1.4e-236 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
JIOHCKLC_00691 6.92e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00692 1.18e-34 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_00693 1.38e-276 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
JIOHCKLC_00694 8.99e-24 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
JIOHCKLC_00695 4.19e-124 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00696 1.91e-47 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00697 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
JIOHCKLC_00698 1.03e-80 - - - L - - - Transposase
JIOHCKLC_00699 2.67e-186 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00700 1.58e-39 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00701 1.17e-147 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00702 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
JIOHCKLC_00703 8.16e-241 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
JIOHCKLC_00704 5.68e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
JIOHCKLC_00705 6.44e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JIOHCKLC_00708 8.07e-148 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JIOHCKLC_00709 4.58e-224 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
JIOHCKLC_00710 6.28e-154 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
JIOHCKLC_00711 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
JIOHCKLC_00712 1.05e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
JIOHCKLC_00713 1.1e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JIOHCKLC_00714 4.26e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JIOHCKLC_00715 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JIOHCKLC_00716 2.77e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
JIOHCKLC_00717 8.75e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
JIOHCKLC_00718 3.65e-308 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JIOHCKLC_00719 6.12e-192 XK27_02985 - - S - - - overlaps another CDS with the same product name
JIOHCKLC_00720 7.63e-185 - - - S - - - overlaps another CDS with the same product name
JIOHCKLC_00721 3.45e-83 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
JIOHCKLC_00722 5.01e-160 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00723 6.44e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
JIOHCKLC_00724 4.91e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00725 8.41e-260 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00726 2.01e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00727 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00728 1.72e-96 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
JIOHCKLC_00730 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
JIOHCKLC_00732 1.89e-178 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
JIOHCKLC_00733 7.33e-218 - - - L - - - Transposase
JIOHCKLC_00734 1e-74 amd - - E - - - COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JIOHCKLC_00735 1.5e-298 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
JIOHCKLC_00736 1.94e-110 - - - - - - - -
JIOHCKLC_00737 7.24e-102 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
JIOHCKLC_00738 1.44e-192 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
JIOHCKLC_00739 6.47e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JIOHCKLC_00740 3.71e-119 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JIOHCKLC_00741 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JIOHCKLC_00742 3.04e-110 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
JIOHCKLC_00743 1.08e-106 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
JIOHCKLC_00744 4.45e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
JIOHCKLC_00745 7.42e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JIOHCKLC_00746 9.67e-76 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
JIOHCKLC_00747 1.47e-178 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
JIOHCKLC_00748 2.06e-181 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
JIOHCKLC_00749 1.5e-61 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
JIOHCKLC_00750 8.28e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
JIOHCKLC_00751 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JIOHCKLC_00752 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JIOHCKLC_00753 3.09e-13 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
JIOHCKLC_00754 1.69e-32 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
JIOHCKLC_00755 2.5e-68 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
JIOHCKLC_00756 3.02e-65 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
JIOHCKLC_00757 9.52e-303 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JIOHCKLC_00758 2.96e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JIOHCKLC_00759 1.63e-146 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JIOHCKLC_00760 2.59e-258 XK27_00055 - - P - - - Major Facilitator
JIOHCKLC_00761 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JIOHCKLC_00762 8.47e-126 - - - V - - - VanZ like family
JIOHCKLC_00763 3e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00764 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
JIOHCKLC_00765 5.83e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JIOHCKLC_00766 8.3e-172 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JIOHCKLC_00767 7.24e-248 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
JIOHCKLC_00768 1.82e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JIOHCKLC_00769 5.93e-299 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
JIOHCKLC_00770 2.82e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JIOHCKLC_00771 4.61e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
JIOHCKLC_00772 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
JIOHCKLC_00773 5.77e-13 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
JIOHCKLC_00774 1.34e-178 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
JIOHCKLC_00775 9e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIOHCKLC_00776 4.03e-14 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIOHCKLC_00777 4.52e-54 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIOHCKLC_00778 3.42e-50 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JIOHCKLC_00779 9.63e-38 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00780 1.15e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00781 1.53e-82 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00782 3.49e-54 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00783 4.99e-78 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00784 2.62e-85 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00785 1.87e-29 - - - - - - - -
JIOHCKLC_00786 2.23e-200 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JIOHCKLC_00787 2.41e-234 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JIOHCKLC_00788 1.03e-284 - - - EGP - - - Major facilitator Superfamily
JIOHCKLC_00789 7.43e-94 adcR - - K - - - transcriptional
JIOHCKLC_00790 1.02e-174 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
JIOHCKLC_00791 1.09e-166 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00792 9.78e-207 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
JIOHCKLC_00793 3.56e-86 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_00794 1.42e-197 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_00795 1.13e-136 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JIOHCKLC_00796 2e-201 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
JIOHCKLC_00797 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
JIOHCKLC_00798 3.92e-163 yeeN - - K - - - transcriptional regulatory protein
JIOHCKLC_00799 9.27e-66 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
JIOHCKLC_00800 1.76e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JIOHCKLC_00801 1.83e-187 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
JIOHCKLC_00802 7.72e-295 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
JIOHCKLC_00803 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JIOHCKLC_00804 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
JIOHCKLC_00805 8.63e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00806 6.35e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JIOHCKLC_00807 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JIOHCKLC_00808 3.93e-49 - - - L - - - Transposase
JIOHCKLC_00809 2.46e-24 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_00810 7.37e-60 - - - L ko:K07483 - ko00000 Transposase
JIOHCKLC_00811 2.84e-203 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
JIOHCKLC_00812 1.72e-30 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00813 1.94e-32 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
JIOHCKLC_00814 2.39e-50 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
JIOHCKLC_00815 1.24e-279 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
JIOHCKLC_00816 8.16e-111 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_00817 5.73e-33 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_00818 6.82e-25 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_00819 1.15e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
JIOHCKLC_00820 4.44e-221 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
JIOHCKLC_00821 1.56e-193 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JIOHCKLC_00822 1.24e-156 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
JIOHCKLC_00823 5.5e-134 yjbK - - S - - - Adenylate cyclase
JIOHCKLC_00824 2.07e-226 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JIOHCKLC_00825 4.54e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
JIOHCKLC_00826 1.46e-77 XK27_04120 - - S - - - Putative amino acid metabolism
JIOHCKLC_00827 1.35e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JIOHCKLC_00828 1.83e-166 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
JIOHCKLC_00829 1.61e-154 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
JIOHCKLC_00830 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
JIOHCKLC_00831 5.39e-251 rgpE - GT2 M ko:K12998 - ko00000,ko01000,ko01003,ko01005 COG0463 Glycosyltransferases involved in cell wall biogenesis
JIOHCKLC_00832 2.09e-287 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JIOHCKLC_00833 3.89e-184 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
JIOHCKLC_00834 3.16e-231 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
JIOHCKLC_00835 5.93e-288 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
JIOHCKLC_00836 1.13e-249 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
JIOHCKLC_00837 4.01e-281 rgpX3 - - S - - - polysaccharide biosynthetic process
JIOHCKLC_00838 3.81e-64 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
JIOHCKLC_00839 2.92e-162 - - - S - - - Glycosyl transferase family 2
JIOHCKLC_00840 7.75e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JIOHCKLC_00841 2.59e-313 - - - - - - - -
JIOHCKLC_00842 8.57e-218 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
JIOHCKLC_00843 0.0 - - - M - - - Psort location CytoplasmicMembrane, score
JIOHCKLC_00844 4.86e-74 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
JIOHCKLC_00845 3.03e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JIOHCKLC_00846 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JIOHCKLC_00847 1.9e-27 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
JIOHCKLC_00848 6.03e-177 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
JIOHCKLC_00849 3.22e-268 arcT - - E - - - Aminotransferase
JIOHCKLC_00850 9.25e-177 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
JIOHCKLC_00851 6.76e-185 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
JIOHCKLC_00852 2.15e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
JIOHCKLC_00853 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JIOHCKLC_00854 5.75e-99 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
JIOHCKLC_00855 5.12e-42 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
JIOHCKLC_00856 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
JIOHCKLC_00857 1.44e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00858 5.28e-24 XK27_00735 - - - - - - -
JIOHCKLC_00859 1.9e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JIOHCKLC_00860 8.41e-11 - - - S - - - Protein of unknown function (DUF4044)
JIOHCKLC_00861 2.22e-173 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
JIOHCKLC_00864 1.25e-85 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
JIOHCKLC_00865 1.17e-40 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
JIOHCKLC_00867 1.61e-197 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
JIOHCKLC_00869 1.22e-140 csn2 - - S ko:K19137 - ko00000,ko02048 CRISPR-associated protein (Cas_Csn2)
JIOHCKLC_00870 7.78e-69 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JIOHCKLC_00871 1.72e-209 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JIOHCKLC_00872 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JIOHCKLC_00873 7.46e-149 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
JIOHCKLC_00874 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JIOHCKLC_00875 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JIOHCKLC_00876 1.07e-141 - - - S - - - IA, variant 1
JIOHCKLC_00877 4.46e-151 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
JIOHCKLC_00878 5.26e-77 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
JIOHCKLC_00880 2.92e-78 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
JIOHCKLC_00881 7.41e-68 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
JIOHCKLC_00882 2.15e-280 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JIOHCKLC_00883 5.63e-136 - - - M - - - Acetyltransferase (GNAT) domain
JIOHCKLC_00884 3.61e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JIOHCKLC_00885 7.31e-125 - - - GK - - - ROK family
JIOHCKLC_00886 9.31e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
JIOHCKLC_00887 8.98e-71 XK27_08050 - - O - - - stress-induced mitochondrial fusion
JIOHCKLC_00888 9.3e-29 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
JIOHCKLC_00889 1.85e-05 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
JIOHCKLC_00890 3.44e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
JIOHCKLC_00891 1.79e-171 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
JIOHCKLC_00892 2e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
JIOHCKLC_00893 1.38e-272 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JIOHCKLC_00894 4.06e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
JIOHCKLC_00895 7.94e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JIOHCKLC_00896 1.05e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JIOHCKLC_00897 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
JIOHCKLC_00898 1.29e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JIOHCKLC_00899 1.17e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
JIOHCKLC_00900 0.0 ydaO - - E - - - amino acid
JIOHCKLC_00901 2.35e-305 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
JIOHCKLC_00902 9.09e-50 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
JIOHCKLC_00903 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
JIOHCKLC_00904 5.38e-219 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
JIOHCKLC_00906 5.11e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
JIOHCKLC_00907 1.22e-97 - - - S - - - QueT transporter
JIOHCKLC_00908 2.2e-68 - - - L - - - Transposase
JIOHCKLC_00909 7.79e-237 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JIOHCKLC_00910 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JIOHCKLC_00911 3.26e-110 ccl - - S - - - cog cog4708
JIOHCKLC_00912 2.38e-210 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
JIOHCKLC_00913 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
JIOHCKLC_00914 1.06e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
JIOHCKLC_00915 2.39e-126 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
JIOHCKLC_00916 2.13e-295 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JIOHCKLC_00917 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
JIOHCKLC_00918 1.38e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
JIOHCKLC_00919 1.76e-183 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
JIOHCKLC_00920 1.33e-112 nodB3 - - G - - - polysaccharide deacetylase
JIOHCKLC_00921 6.52e-31 nodB3 - - G - - - polysaccharide deacetylase
JIOHCKLC_00922 2.91e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
JIOHCKLC_00923 4.12e-56 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
JIOHCKLC_00924 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JIOHCKLC_00925 6.14e-205 corA - - P - - - CorA-like protein
JIOHCKLC_00926 7.5e-83 yjqA - - S - - - Bacterial PH domain
JIOHCKLC_00927 4.57e-129 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
JIOHCKLC_00928 5.28e-203 rgg - - K - - - Transcriptional activator, Rgg GadR MutR family
JIOHCKLC_00929 1.09e-257 yjbB - - G - - - Permeases of the major facilitator superfamily
JIOHCKLC_00930 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JIOHCKLC_00931 1.63e-155 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
JIOHCKLC_00932 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JIOHCKLC_00936 9.46e-200 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
JIOHCKLC_00937 2.74e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_00938 3.24e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00939 8.58e-149 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_00940 9.64e-248 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
JIOHCKLC_00941 9.48e-43 copZ - - P - - - Heavy metal-associated domain protein
JIOHCKLC_00942 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
JIOHCKLC_00943 4.28e-97 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
JIOHCKLC_00944 6.12e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JIOHCKLC_00945 1.66e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JIOHCKLC_00946 1.25e-127 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
JIOHCKLC_00947 2.28e-172 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
JIOHCKLC_00948 2.69e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JIOHCKLC_00949 2.03e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
JIOHCKLC_00950 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JIOHCKLC_00951 9.49e-57 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
JIOHCKLC_00952 1.25e-74 - - - - - - - -
JIOHCKLC_00953 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
JIOHCKLC_00955 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JIOHCKLC_00956 6.16e-38 - - - L - - - transposase activity
JIOHCKLC_00957 6.01e-167 - - - K - - - transcriptional regulator, MerR family
JIOHCKLC_00958 2.17e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
JIOHCKLC_00959 8.12e-80 WQ51_02910 - - S - - - Protein of unknown function, DUF536
JIOHCKLC_00960 8.66e-83 XK27_02560 - - S - - - cog cog2151
JIOHCKLC_00961 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
JIOHCKLC_00962 9.59e-289 ytfP - - S ko:K07007 - ko00000 Flavoprotein
JIOHCKLC_00964 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JIOHCKLC_00965 8.46e-197 ytmP - - M - - - Phosphotransferase
JIOHCKLC_00966 7.69e-232 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
JIOHCKLC_00967 1.5e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_00968 6.15e-95 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JIOHCKLC_00969 4.47e-13 - - - - - - - -
JIOHCKLC_00970 1.93e-67 - - - S - - - CD20-like family
JIOHCKLC_00971 3.82e-140 - - - - - - - -
JIOHCKLC_00973 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
JIOHCKLC_00974 4.36e-263 ylbM - - S - - - Belongs to the UPF0348 family
JIOHCKLC_00975 2.78e-179 XK27_06665 - - Q - - - Methyltransferase domain protein
JIOHCKLC_00976 9.81e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JIOHCKLC_00977 8.21e-139 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
JIOHCKLC_00978 5.51e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JIOHCKLC_00979 1.59e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
JIOHCKLC_00980 2.78e-275 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JIOHCKLC_00981 1.84e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
JIOHCKLC_00982 3.34e-194 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JIOHCKLC_00983 1.94e-76 - - - - - - - -
JIOHCKLC_00984 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JIOHCKLC_00985 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JIOHCKLC_00986 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JIOHCKLC_00987 6.32e-42 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
JIOHCKLC_00988 1.06e-187 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
JIOHCKLC_00989 5.44e-98 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
JIOHCKLC_00990 1.38e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JIOHCKLC_00991 3.85e-198 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
JIOHCKLC_00992 3.02e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
JIOHCKLC_00993 6.34e-182 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JIOHCKLC_00994 2.61e-303 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
JIOHCKLC_00995 7.54e-99 XK27_03180 - - T - - - universal stress protein
JIOHCKLC_00998 6.98e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JIOHCKLC_00999 2.02e-304 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
JIOHCKLC_01000 1.29e-185 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01001 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
JIOHCKLC_01003 9e-127 mraW1 - - J - - - (SAM)-dependent
JIOHCKLC_01004 1.51e-236 ytqA - - S ko:K07139 - ko00000 radical SAM protein
JIOHCKLC_01005 7.98e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
JIOHCKLC_01006 7.91e-115 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JIOHCKLC_01007 9.01e-121 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
JIOHCKLC_01008 4.78e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JIOHCKLC_01009 1.48e-13 - - - S - - - Protein of unknown function (DUF4059)
JIOHCKLC_01010 1.61e-168 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01011 2.53e-208 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_01012 1.04e-194 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
JIOHCKLC_01014 2.53e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JIOHCKLC_01015 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
JIOHCKLC_01016 1.98e-189 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
JIOHCKLC_01017 9.32e-112 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JIOHCKLC_01018 5.58e-60 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
JIOHCKLC_01019 1.96e-113 - - - D - - - nuclear chromosome segregation
JIOHCKLC_01020 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
JIOHCKLC_01021 2.51e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_01022 4.14e-235 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
JIOHCKLC_01023 6.61e-179 cppA - - E - - - CppA N-terminal
JIOHCKLC_01024 2.69e-56 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
JIOHCKLC_01025 7.59e-212 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
JIOHCKLC_01026 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JIOHCKLC_01029 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
JIOHCKLC_01030 9.35e-36 blpT - - - - - - -
JIOHCKLC_01031 4.64e-159 blpT - - - - - - -
JIOHCKLC_01035 0.000703 - - - - - - - -
JIOHCKLC_01036 2.55e-33 - - - S - - - Bacteriocin class II with double-glycine leader peptide
JIOHCKLC_01039 1.56e-174 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
JIOHCKLC_01040 2.23e-298 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
JIOHCKLC_01042 5.03e-311 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
JIOHCKLC_01043 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JIOHCKLC_01044 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_01045 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_01047 1.63e-121 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
JIOHCKLC_01048 3.19e-285 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JIOHCKLC_01049 6.98e-139 yutD - - J - - - protein conserved in bacteria
JIOHCKLC_01050 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
JIOHCKLC_01052 5.56e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JIOHCKLC_01053 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JIOHCKLC_01054 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
JIOHCKLC_01055 2.25e-61 ftsL - - D - - - cell division protein FtsL
JIOHCKLC_01056 4.73e-244 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JIOHCKLC_01057 3.08e-118 - - - - - - - -
JIOHCKLC_01058 1.08e-54 - - - - - - - -
JIOHCKLC_01060 1.58e-42 - - - J - - - Protein of unknown function (DUF805)
JIOHCKLC_01061 1.79e-11 - - - D - - - nuclear chromosome segregation
JIOHCKLC_01062 1.22e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JIOHCKLC_01063 4.99e-182 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JIOHCKLC_01064 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
JIOHCKLC_01065 3.02e-171 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_01066 1.22e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
JIOHCKLC_01067 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
JIOHCKLC_01068 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JIOHCKLC_01069 2.47e-155 - - - S - - - membrane
JIOHCKLC_01070 1.31e-98 - - - K - - - LytTr DNA-binding domain
JIOHCKLC_01071 2.92e-81 - - - KT - - - response to antibiotic
JIOHCKLC_01072 2.76e-20 - - - KT - - - response to antibiotic
JIOHCKLC_01073 5.56e-93 yebC - - M - - - Membrane
JIOHCKLC_01074 1.77e-24 yebC - - M - - - Membrane
JIOHCKLC_01075 0.0 - - - S - - - hydrolases of the HAD superfamily
JIOHCKLC_01076 8.08e-223 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JIOHCKLC_01077 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JIOHCKLC_01078 1.16e-244 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JIOHCKLC_01079 1.75e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JIOHCKLC_01080 1.01e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JIOHCKLC_01081 2.03e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JIOHCKLC_01082 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JIOHCKLC_01084 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
JIOHCKLC_01085 2.37e-220 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
JIOHCKLC_01086 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_01087 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
JIOHCKLC_01088 3.67e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional
JIOHCKLC_01089 2.67e-96 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JIOHCKLC_01090 9.01e-81 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
JIOHCKLC_01091 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JIOHCKLC_01092 1.43e-109 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
JIOHCKLC_01093 2.5e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
JIOHCKLC_01095 6.03e-55 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
JIOHCKLC_01096 3.94e-75 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
JIOHCKLC_01099 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JIOHCKLC_01100 8.18e-216 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
JIOHCKLC_01101 5.91e-159 - - - S - - - Pfam PF06570
JIOHCKLC_01103 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JIOHCKLC_01104 1.2e-117 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JIOHCKLC_01105 3.11e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
JIOHCKLC_01106 1.39e-50 XK27_05745 - - - - - - -
JIOHCKLC_01107 5.55e-292 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
JIOHCKLC_01110 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JIOHCKLC_01111 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JIOHCKLC_01112 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
JIOHCKLC_01113 5.78e-19 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JIOHCKLC_01114 4.7e-206 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JIOHCKLC_01115 3.19e-146 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
JIOHCKLC_01116 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JIOHCKLC_01117 3.85e-63 azlD - - E - - - branched-chain amino acid
JIOHCKLC_01118 7.27e-148 XK27_12120 - - E - - - AzlC protein
JIOHCKLC_01119 1.64e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JIOHCKLC_01120 4.41e-96 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JIOHCKLC_01121 2.39e-156 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
JIOHCKLC_01122 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
JIOHCKLC_01123 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JIOHCKLC_01124 4.75e-53 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
JIOHCKLC_01125 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
JIOHCKLC_01126 1.12e-83 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
JIOHCKLC_01127 1.08e-113 - - - S - - - Fusaric acid resistance protein-like
JIOHCKLC_01128 9.51e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
JIOHCKLC_01129 5.98e-47 - - - K - - - sequence-specific DNA binding
JIOHCKLC_01131 0.0 - - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
JIOHCKLC_01132 1.97e-295 spaC2 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
JIOHCKLC_01133 9.08e-237 - - - EGP - - - Major Facilitator Superfamily
JIOHCKLC_01134 4.95e-33 - 3.6.4.12 - - ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 -
JIOHCKLC_01135 4.37e-119 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Divergent AAA domain protein
JIOHCKLC_01136 4.74e-286 int - - L - - - Belongs to the 'phage' integrase family
JIOHCKLC_01137 1.67e-51 - - - S - - - Helix-turn-helix domain
JIOHCKLC_01138 4.77e-220 - - - - - - - -
JIOHCKLC_01140 4.04e-95 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
JIOHCKLC_01141 6.53e-118 - - - L ko:K07498 - ko00000 Transposase
JIOHCKLC_01142 3.89e-285 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
JIOHCKLC_01143 1.76e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
JIOHCKLC_01144 1.6e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
JIOHCKLC_01145 4.76e-50 ais - - G - - - alpha-ribazole phosphatase activity
JIOHCKLC_01146 4.65e-186 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
JIOHCKLC_01147 5.34e-134 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
JIOHCKLC_01148 4.82e-254 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JIOHCKLC_01149 2.93e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JIOHCKLC_01150 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
JIOHCKLC_01151 4.85e-258 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JIOHCKLC_01152 1.02e-176 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JIOHCKLC_01153 3.02e-176 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
JIOHCKLC_01154 7.01e-81 hmpT - - S - - - membrane
JIOHCKLC_01155 3.18e-21 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_01156 3.89e-241 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JIOHCKLC_01157 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JIOHCKLC_01158 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JIOHCKLC_01159 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JIOHCKLC_01160 1.97e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
JIOHCKLC_01161 5.61e-228 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
JIOHCKLC_01162 4.63e-236 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
JIOHCKLC_01163 2.73e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
JIOHCKLC_01164 2.76e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
JIOHCKLC_01165 5.32e-209 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JIOHCKLC_01167 1.06e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JIOHCKLC_01168 1.81e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JIOHCKLC_01169 2.13e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
JIOHCKLC_01170 9.39e-98 yneT - - S ko:K06929 - ko00000 CoA-binding protein
JIOHCKLC_01171 5.36e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
JIOHCKLC_01172 5.03e-183 - - - S - - - Macro domain protein
JIOHCKLC_01173 1.78e-10 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
JIOHCKLC_01174 3.38e-72 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
JIOHCKLC_01177 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JIOHCKLC_01178 2.76e-45 - - - L ko:K07491 - ko00000 Transposase
JIOHCKLC_01179 9.33e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
JIOHCKLC_01180 7.21e-239 jag - - S ko:K06346 - ko00000 RNA-binding protein
JIOHCKLC_01181 1.8e-180 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JIOHCKLC_01182 8.28e-73 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JIOHCKLC_01183 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
JIOHCKLC_01184 3.19e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
JIOHCKLC_01185 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JIOHCKLC_01186 1.75e-24 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
JIOHCKLC_01187 3.66e-83 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
JIOHCKLC_01188 1.82e-97 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
JIOHCKLC_01189 1.66e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JIOHCKLC_01190 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JIOHCKLC_01191 3.28e-66 - - - S - - - Protein of unknown function (DUF3397)
JIOHCKLC_01192 9.62e-116 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
JIOHCKLC_01193 7.36e-75 - - - S - - - Mitochondrial biogenesis AIM24
JIOHCKLC_01194 1.64e-16 - - - S - - - Mitochondrial biogenesis AIM24
JIOHCKLC_01195 1.08e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JIOHCKLC_01196 2.98e-104 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
JIOHCKLC_01197 1.24e-26 XK27_09620 - - S - - - FMN reductase (NADPH) activity
JIOHCKLC_01198 2.97e-100 - - - S - - - reductase
JIOHCKLC_01199 4.64e-77 XK27_09615 - - C ko:K19784 - ko00000 reductase
JIOHCKLC_01200 3.86e-182 XK27_09615 - - C ko:K19784 - ko00000 reductase
JIOHCKLC_01201 4.96e-82 nirC_1 - - P - - - Formate nitrite transporter
JIOHCKLC_01202 9.39e-83 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
JIOHCKLC_01203 5.94e-238 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
JIOHCKLC_01204 7.92e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
JIOHCKLC_01205 2.39e-154 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
JIOHCKLC_01206 2.82e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JIOHCKLC_01207 1.34e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JIOHCKLC_01208 6.92e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JIOHCKLC_01209 9.35e-64 - - - S ko:K07025 - ko00000 glycolate biosynthetic process
JIOHCKLC_01210 1.53e-85 - - - S ko:K07025 - ko00000 phosphatase activity
JIOHCKLC_01211 4.03e-202 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
JIOHCKLC_01214 1.7e-117 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JIOHCKLC_01215 3.13e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JIOHCKLC_01216 2.25e-49 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
JIOHCKLC_01217 3.62e-245 yeeE - - S ko:K07112 - ko00000 Sulphur transport
JIOHCKLC_01218 5.51e-147 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JIOHCKLC_01219 3.48e-73 ytpP - - CO - - - Thioredoxin
JIOHCKLC_01221 3.7e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
JIOHCKLC_01222 4.76e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JIOHCKLC_01223 1.6e-141 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
JIOHCKLC_01225 1.2e-85 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
JIOHCKLC_01226 4.3e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
JIOHCKLC_01227 8.04e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JIOHCKLC_01228 2.04e-227 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
JIOHCKLC_01229 5.13e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
JIOHCKLC_01230 2.56e-94 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
JIOHCKLC_01231 1.28e-21 - - - NU - - - Type II secretory pathway pseudopilin
JIOHCKLC_01232 1.03e-75 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
JIOHCKLC_01233 1.06e-60 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
JIOHCKLC_01234 3.69e-195 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
JIOHCKLC_01235 3.13e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JIOHCKLC_01236 3.93e-91 - - - S - - - cog cog4699
JIOHCKLC_01237 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JIOHCKLC_01238 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JIOHCKLC_01239 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
JIOHCKLC_01240 2.34e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JIOHCKLC_01241 2.67e-250 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JIOHCKLC_01242 2.89e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
JIOHCKLC_01243 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
JIOHCKLC_01244 1.83e-10 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
JIOHCKLC_01245 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
JIOHCKLC_01246 1.57e-11 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
JIOHCKLC_01247 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
JIOHCKLC_01248 1.87e-76 asp - - S - - - cog cog1302
JIOHCKLC_01249 1.31e-286 norN - - V - - - Mate efflux family protein
JIOHCKLC_01250 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
JIOHCKLC_01251 4.79e-77 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
JIOHCKLC_01252 3.04e-48 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 hydroxyacid-oxoacid transhydrogenase activity
JIOHCKLC_01253 5.74e-86 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
JIOHCKLC_01254 9.16e-161 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
JIOHCKLC_01255 9.31e-84 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
JIOHCKLC_01256 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
JIOHCKLC_01257 3.67e-49 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
JIOHCKLC_01258 4.39e-90 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
JIOHCKLC_01259 4.14e-87 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
JIOHCKLC_01260 3.49e-72 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
JIOHCKLC_01261 2.66e-29 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
JIOHCKLC_01262 6.51e-114 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
JIOHCKLC_01263 1.17e-122 ywlG - - S - - - Belongs to the UPF0340 family
JIOHCKLC_01266 7.69e-18 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
JIOHCKLC_01267 4.19e-101 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
JIOHCKLC_01268 2.79e-55 - - - K - - - Putative DNA-binding domain
JIOHCKLC_01269 3.75e-18 - - - M - - - Acetyltransferase GNAT Family
JIOHCKLC_01270 5.45e-159 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JIOHCKLC_01271 5.34e-176 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
JIOHCKLC_01276 2.03e-53 - - - - - - - -
JIOHCKLC_01277 4.01e-41 - - - - - - - -
JIOHCKLC_01278 4.65e-42 - - - S - - - Hypothetical protein (DUF2513)
JIOHCKLC_01279 0.000346 - - - - - - - -
JIOHCKLC_01281 1.14e-277 - - - S - - - MvaI/BcnI restriction endonuclease family
JIOHCKLC_01282 5.73e-05 - - - K - - - Cro/C1-type HTH DNA-binding domain
JIOHCKLC_01283 0.0 - - - H - - - C-5 cytosine-specific DNA methylase
JIOHCKLC_01284 2.85e-210 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
JIOHCKLC_01286 7.55e-142 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
JIOHCKLC_01287 8e-24 - - - H - - - gamma-glutamylcysteine synthetase
JIOHCKLC_01288 2.3e-15 - - - H - - - gamma-glutamylcysteine synthetase
JIOHCKLC_01289 3.69e-42 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
JIOHCKLC_01290 2.9e-146 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
JIOHCKLC_01291 2.13e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
JIOHCKLC_01292 5.37e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JIOHCKLC_01293 1.57e-80 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JIOHCKLC_01294 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JIOHCKLC_01295 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
JIOHCKLC_01296 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JIOHCKLC_01297 2.61e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JIOHCKLC_01298 2.12e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JIOHCKLC_01299 1.03e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
JIOHCKLC_01300 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
JIOHCKLC_01301 9.94e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JIOHCKLC_01302 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JIOHCKLC_01303 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JIOHCKLC_01304 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JIOHCKLC_01305 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JIOHCKLC_01306 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JIOHCKLC_01307 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JIOHCKLC_01308 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JIOHCKLC_01309 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JIOHCKLC_01310 4.36e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
JIOHCKLC_01311 3.58e-93 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JIOHCKLC_01312 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JIOHCKLC_01313 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JIOHCKLC_01314 1.99e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JIOHCKLC_01315 7.19e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JIOHCKLC_01316 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JIOHCKLC_01317 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
JIOHCKLC_01318 7.78e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JIOHCKLC_01319 7.41e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
JIOHCKLC_01320 1.78e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JIOHCKLC_01321 0.0 XK27_09800 - - I - - - Acyltransferase
JIOHCKLC_01322 2.43e-47 - - - S - - - MORN repeat protein
JIOHCKLC_01323 2.29e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JIOHCKLC_01324 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JIOHCKLC_01325 3.91e-109 flaR - - F - - - topology modulation protein
JIOHCKLC_01326 3.14e-244 - - - EGP - - - Major Facilitator Superfamily
JIOHCKLC_01327 3.96e-253 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
JIOHCKLC_01328 1.19e-55 B4168_4126 - - L ko:K07493 - ko00000 Transposase
JIOHCKLC_01330 7.46e-200 - - - K ko:K20373,ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
JIOHCKLC_01331 0.0 - - - KLT - - - serine threonine protein kinase
JIOHCKLC_01332 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
JIOHCKLC_01333 1.98e-17 - - - K - - - Transcriptional activator, Rgg GadR MutR family
JIOHCKLC_01334 2.7e-164 Z012_04635 - - K - - - sequence-specific DNA binding
JIOHCKLC_01336 6.96e-67 - - - C ko:K06871 - ko00000 Radical SAM
JIOHCKLC_01337 5.44e-199 - - - C ko:K06871 - ko00000 Radical SAM
JIOHCKLC_01338 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
JIOHCKLC_01339 5.53e-79 - - - K - - - sequence-specific DNA binding
JIOHCKLC_01340 1.59e-19 - - - K - - - Cro/C1-type HTH DNA-binding domain
JIOHCKLC_01341 1.74e-169 - - - L - - - Belongs to the 'phage' integrase family
JIOHCKLC_01343 3.74e-303 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
JIOHCKLC_01344 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
JIOHCKLC_01345 3.4e-59 yrzL - - S - - - Belongs to the UPF0297 family
JIOHCKLC_01346 8.4e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JIOHCKLC_01347 2.7e-62 yrzB - - S - - - Belongs to the UPF0473 family
JIOHCKLC_01348 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
JIOHCKLC_01349 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
JIOHCKLC_01350 7.68e-20 - - - - - - - -
JIOHCKLC_01351 1.31e-118 - - - K - - - acetyltransferase
JIOHCKLC_01352 1.26e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JIOHCKLC_01353 4.85e-189 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
JIOHCKLC_01354 5.96e-213 XK27_01785 - - S - - - cog cog1284
JIOHCKLC_01355 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JIOHCKLC_01357 6.78e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
JIOHCKLC_01358 9.64e-171 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
JIOHCKLC_01359 2.42e-45 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
JIOHCKLC_01360 4.33e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
JIOHCKLC_01361 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
JIOHCKLC_01364 1.68e-55 yegS - - I - - - Diacylglycerol kinase
JIOHCKLC_01365 1.04e-103 yegS - - I - - - Diacylglycerol kinase
JIOHCKLC_01366 8.43e-124 - - - S - - - Hydrophobic domain protein
JIOHCKLC_01368 7.98e-45 ytgB - - S - - - Membrane
JIOHCKLC_01369 4.42e-130 - - - - - - - -
JIOHCKLC_01370 7.53e-33 - - - S - - - Small integral membrane protein
JIOHCKLC_01371 7.56e-116 - - - M - - - Protein conserved in bacteria
JIOHCKLC_01372 1.17e-34 - - - K - - - CsbD-like
JIOHCKLC_01373 2.9e-18 XK27_06885 - - L - - - hydrolase
JIOHCKLC_01374 3.75e-26 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
JIOHCKLC_01375 4.32e-33 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
JIOHCKLC_01376 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
JIOHCKLC_01377 5.59e-29 - - - S - - - Protein of unknown function (DUF1700)
JIOHCKLC_01378 7.22e-121 - - - S - - - Putative adhesin
JIOHCKLC_01379 5.13e-270 XK27_06930 - - V ko:K01421 - ko00000 domain protein
JIOHCKLC_01380 3.98e-124 XK27_06935 - - K - - - transcriptional regulator
JIOHCKLC_01381 7.97e-73 XK27_04840 - - M ko:K08987 - ko00000 Membrane
JIOHCKLC_01382 2.05e-09 - - - - - - - -
JIOHCKLC_01383 5.92e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JIOHCKLC_01384 3.05e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
JIOHCKLC_01385 1.29e-312 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
JIOHCKLC_01386 1.24e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
JIOHCKLC_01387 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
JIOHCKLC_01388 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JIOHCKLC_01389 1.46e-101 - - - F - - - NUDIX domain
JIOHCKLC_01390 1.62e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JIOHCKLC_01391 0.0 - - - S - - - Bacterial membrane protein, YfhO
JIOHCKLC_01392 5.49e-123 isaA - - M - - - Immunodominant staphylococcal antigen A
JIOHCKLC_01393 1.87e-120 lytE - - M - - - LysM domain protein
JIOHCKLC_01394 2.56e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JIOHCKLC_01395 2.6e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JIOHCKLC_01396 4.68e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JIOHCKLC_01397 5.4e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JIOHCKLC_01398 8.84e-185 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
JIOHCKLC_01399 7.64e-309 ymfH - - S - - - Peptidase M16
JIOHCKLC_01400 9.12e-301 albE - - S - - - Peptidase M16
JIOHCKLC_01401 3.7e-69 yaaA - - S - - - S4 domain protein YaaA
JIOHCKLC_01402 2.24e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JIOHCKLC_01403 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JIOHCKLC_01404 1.17e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
JIOHCKLC_01405 3.96e-195 XK27_10395 - - S - - - membrane
JIOHCKLC_01406 0.0 ykpA - - S - - - abc transporter atp-binding protein
JIOHCKLC_01407 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
JIOHCKLC_01411 3.66e-155 yveI - - S - - - Psort location CytoplasmicMembrane, score
JIOHCKLC_01412 1.79e-111 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JIOHCKLC_01413 2.58e-261 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
JIOHCKLC_01414 9.27e-172 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
JIOHCKLC_01415 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JIOHCKLC_01416 1.1e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JIOHCKLC_01417 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
JIOHCKLC_01418 3.04e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JIOHCKLC_01419 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JIOHCKLC_01420 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JIOHCKLC_01421 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JIOHCKLC_01422 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
JIOHCKLC_01423 1.94e-05 - - - - - - - -
JIOHCKLC_01424 2.66e-307 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
JIOHCKLC_01425 3.77e-307 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JIOHCKLC_01426 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
JIOHCKLC_01427 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JIOHCKLC_01428 3.61e-132 - - - L ko:K07485 - ko00000 Transposase
JIOHCKLC_01429 6.44e-65 - - - L - - - Transposase
JIOHCKLC_01430 1.52e-48 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_01431 6.11e-31 - - - L - - - Transposase
JIOHCKLC_01432 6.09e-40 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_01434 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
JIOHCKLC_01437 1.16e-57 - - - - - - - -
JIOHCKLC_01438 5.62e-75 WQ51_06355 - - S - - - TM2 domain
JIOHCKLC_01439 1.17e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
JIOHCKLC_01440 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
JIOHCKLC_01441 6.28e-35 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
JIOHCKLC_01442 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
JIOHCKLC_01443 1.17e-110 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
JIOHCKLC_01444 6.76e-73 cof - - Q - - - phosphatase activity
JIOHCKLC_01445 1.89e-47 cof - - Q - - - phosphatase activity
JIOHCKLC_01446 6.57e-176 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
JIOHCKLC_01447 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
JIOHCKLC_01448 1.73e-53 napB - - K - - - transcriptional
JIOHCKLC_01449 4.06e-116 - - - S ko:K06889 - ko00000 thiolester hydrolase activity
JIOHCKLC_01450 1.83e-177 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
JIOHCKLC_01451 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JIOHCKLC_01452 6.15e-195 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JIOHCKLC_01453 1.37e-99 yhaI - - L - - - Membrane
JIOHCKLC_01454 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
JIOHCKLC_01455 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
JIOHCKLC_01456 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JIOHCKLC_01457 8.82e-124 ypsA - - S - - - Belongs to the UPF0398 family
JIOHCKLC_01458 3.39e-67 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JIOHCKLC_01459 6.16e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
JIOHCKLC_01460 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
JIOHCKLC_01461 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
JIOHCKLC_01462 3.69e-27 XK27_11680 - - - - - - -
JIOHCKLC_01463 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
JIOHCKLC_01464 1.24e-104 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
JIOHCKLC_01465 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JIOHCKLC_01466 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JIOHCKLC_01467 2.91e-79 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_01468 1.52e-211 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JIOHCKLC_01469 3.32e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
JIOHCKLC_01470 6.83e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JIOHCKLC_01471 8.25e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
JIOHCKLC_01472 2.43e-145 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
JIOHCKLC_01475 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JIOHCKLC_01476 2.12e-119 - - - K - - - transcriptional regulator
JIOHCKLC_01477 5.74e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
JIOHCKLC_01478 1.89e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
JIOHCKLC_01479 1.64e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JIOHCKLC_01480 7.82e-128 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
JIOHCKLC_01481 1.74e-111 ykuL - - S - - - CBS domain
JIOHCKLC_01482 3.26e-172 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
JIOHCKLC_01483 5.32e-153 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JIOHCKLC_01484 7.56e-129 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JIOHCKLC_01485 1.82e-178 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
JIOHCKLC_01486 1.23e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
JIOHCKLC_01487 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
JIOHCKLC_01488 1.15e-313 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
JIOHCKLC_01489 2.22e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JIOHCKLC_01490 4.83e-118 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JIOHCKLC_01491 6.62e-148 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
JIOHCKLC_01492 1.03e-206 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
JIOHCKLC_01493 5.6e-45 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
JIOHCKLC_01494 1.05e-45 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JIOHCKLC_01495 3.47e-78 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JIOHCKLC_01496 5.3e-35 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
JIOHCKLC_01497 2.72e-36 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
JIOHCKLC_01498 1.34e-89 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JIOHCKLC_01499 5.77e-68 yhaI - - L - - - Membrane
JIOHCKLC_01500 1.76e-43 - - - S - - - Domain of unknown function (DUF4173)
JIOHCKLC_01501 8.35e-163 - - - S - - - Domain of unknown function (DUF4173)
JIOHCKLC_01502 2.16e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
JIOHCKLC_01503 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
JIOHCKLC_01504 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
JIOHCKLC_01505 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JIOHCKLC_01506 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
JIOHCKLC_01507 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JIOHCKLC_01508 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JIOHCKLC_01509 9.91e-204 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JIOHCKLC_01510 5e-227 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
JIOHCKLC_01511 6.8e-176 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
JIOHCKLC_01512 4.48e-170 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
JIOHCKLC_01513 3.69e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
JIOHCKLC_01514 0.0 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JIOHCKLC_01515 0.0 - - - F - - - NUDIX domain
JIOHCKLC_01516 7.28e-268 - - - EGP - - - Transmembrane secretion effector
JIOHCKLC_01517 2.6e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
JIOHCKLC_01518 1.26e-212 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
JIOHCKLC_01519 6.08e-112 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
JIOHCKLC_01520 1.48e-82 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
JIOHCKLC_01521 1.96e-82 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
JIOHCKLC_01522 2.17e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JIOHCKLC_01523 1.77e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
JIOHCKLC_01524 7.28e-268 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JIOHCKLC_01525 5.95e-202 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
JIOHCKLC_01526 5.41e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
JIOHCKLC_01527 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01528 2.29e-187 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
JIOHCKLC_01529 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JIOHCKLC_01530 1.65e-14 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
JIOHCKLC_01531 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
JIOHCKLC_01532 1e-309 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
JIOHCKLC_01533 1.5e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
JIOHCKLC_01534 1.14e-118 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
JIOHCKLC_01535 3.82e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JIOHCKLC_01536 0.0 covS - - T - - - Histidine kinase
JIOHCKLC_01537 1.74e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JIOHCKLC_01538 4.48e-277 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
JIOHCKLC_01539 1.26e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
JIOHCKLC_01540 5.05e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
JIOHCKLC_01542 1.99e-45 - - - - - - - -
JIOHCKLC_01543 3.94e-35 - - - L ko:K07497 - ko00000 Integrase core domain protein
JIOHCKLC_01544 1.15e-12 - - - L ko:K07497 - ko00000 transposition
JIOHCKLC_01545 1.74e-30 - - - L - - - Transposase
JIOHCKLC_01546 1.92e-38 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_01547 2.31e-306 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JIOHCKLC_01548 1.52e-81 manO - - S - - - protein conserved in bacteria
JIOHCKLC_01549 8.21e-215 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
JIOHCKLC_01550 4.19e-162 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
JIOHCKLC_01551 6.6e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_01552 1.84e-181 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
JIOHCKLC_01553 1.46e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
JIOHCKLC_01554 4.39e-316 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
JIOHCKLC_01555 1.54e-101 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
JIOHCKLC_01556 6.67e-120 - - - M - - - Acetyltransferase GNAT Family
JIOHCKLC_01557 1.29e-280 brpA - - K - - - Transcriptional
JIOHCKLC_01558 3.06e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
JIOHCKLC_01559 2.28e-270 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
JIOHCKLC_01560 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
JIOHCKLC_01561 2.19e-56 ylxQ - - J - - - ribosomal protein
JIOHCKLC_01562 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JIOHCKLC_01563 9.81e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JIOHCKLC_01564 1.44e-29 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
JIOHCKLC_01565 2.68e-49 - 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
JIOHCKLC_01566 5.54e-273 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
JIOHCKLC_01567 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JIOHCKLC_01568 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
JIOHCKLC_01569 4.89e-115 pacL - - P - - - cation transport ATPase
JIOHCKLC_01570 1.76e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
JIOHCKLC_01571 5.65e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JIOHCKLC_01572 3.28e-06 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
JIOHCKLC_01573 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JIOHCKLC_01574 2.64e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JIOHCKLC_01575 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
JIOHCKLC_01576 4.33e-62 ylbG - - S - - - UPF0298 protein
JIOHCKLC_01577 3.09e-268 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
JIOHCKLC_01578 8.19e-190 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
JIOHCKLC_01579 7.76e-183 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
JIOHCKLC_01580 3.96e-177 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
JIOHCKLC_01581 5.36e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
JIOHCKLC_01582 6.64e-90 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
JIOHCKLC_01583 2.44e-54 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
JIOHCKLC_01584 1.85e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
JIOHCKLC_01585 3.86e-143 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
JIOHCKLC_01586 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JIOHCKLC_01587 1.19e-157 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
JIOHCKLC_01588 1.18e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JIOHCKLC_01595 9.95e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
JIOHCKLC_01596 9.03e-141 - - - S - - - Domain of unknown function (DUF1803)
JIOHCKLC_01597 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
JIOHCKLC_01598 4.96e-173 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
JIOHCKLC_01599 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JIOHCKLC_01600 9.23e-246 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
JIOHCKLC_01601 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
JIOHCKLC_01602 5.93e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
JIOHCKLC_01603 4.99e-180 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
JIOHCKLC_01604 4.43e-95 XK27_02735 - - K - - - Transcriptional regulator, MarR family
JIOHCKLC_01605 1.88e-224 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JIOHCKLC_01606 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
JIOHCKLC_01607 1.31e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
JIOHCKLC_01608 1.35e-210 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
JIOHCKLC_01609 8.26e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
JIOHCKLC_01610 2.6e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JIOHCKLC_01611 2.48e-87 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JIOHCKLC_01612 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JIOHCKLC_01613 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JIOHCKLC_01614 1.4e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JIOHCKLC_01615 3.26e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JIOHCKLC_01616 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JIOHCKLC_01617 4.67e-162 - - - L ko:K07498 - ko00000 Transposase
JIOHCKLC_01619 0.0 - - - S - - - Protein of unknown function (DUF3114)
JIOHCKLC_01620 1.78e-68 - - - K - - - Acetyltransferase GNAT Family
JIOHCKLC_01621 1.23e-249 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 (ABC) transporter
JIOHCKLC_01622 5.01e-93 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
JIOHCKLC_01623 1.44e-106 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
JIOHCKLC_01624 1.71e-143 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
JIOHCKLC_01625 1.53e-198 tra981A - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
JIOHCKLC_01626 1.78e-51 - - - L ko:K07483 - ko00000 transposase activity
JIOHCKLC_01627 3.13e-311 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
JIOHCKLC_01628 8.72e-111 - - - L ko:K07485 - ko00000 Transposase
JIOHCKLC_01629 7.9e-165 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
JIOHCKLC_01630 7.23e-209 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JIOHCKLC_01631 3.88e-101 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
JIOHCKLC_01632 7.12e-302 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
JIOHCKLC_01633 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JIOHCKLC_01634 9.28e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
JIOHCKLC_01635 3.47e-06 - - - - - - - -
JIOHCKLC_01636 1.8e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
JIOHCKLC_01637 6.04e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JIOHCKLC_01638 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JIOHCKLC_01639 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JIOHCKLC_01640 1.13e-37 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
JIOHCKLC_01641 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
JIOHCKLC_01642 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
JIOHCKLC_01643 5.47e-168 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JIOHCKLC_01644 2.74e-84 WQ51_03320 - - S - - - cog cog4835
JIOHCKLC_01645 3.86e-78 - - - S - - - EDD domain protein, DegV family
JIOHCKLC_01646 4.81e-96 - - - S - - - EDD domain protein, DegV family
JIOHCKLC_01647 6.34e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JIOHCKLC_01648 7.9e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JIOHCKLC_01649 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01650 2.24e-27 - - - S - - - Short repeat of unknown function (DUF308)
JIOHCKLC_01651 1.44e-177 - - - F - - - AdP-ribose pyrophosphatase
JIOHCKLC_01652 1.16e-175 nadR - - H - - - adenylyltransferase
JIOHCKLC_01653 1.29e-73 nadR - - H - - - adenylyltransferase
JIOHCKLC_01654 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
JIOHCKLC_01655 3.88e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
JIOHCKLC_01656 4.4e-101 - - - K - - - DNA-binding transcription factor activity
JIOHCKLC_01657 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01658 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01659 6.54e-58 - - - K - - - Acetyltransferase (GNAT) family
JIOHCKLC_01660 1.53e-100 sptS - - T - - - Histidine kinase
JIOHCKLC_01661 1.38e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
JIOHCKLC_01662 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JIOHCKLC_01663 1.67e-206 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
JIOHCKLC_01664 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
JIOHCKLC_01665 6.58e-213 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
JIOHCKLC_01666 3.19e-90 sip - - M - - - LysM domain protein
JIOHCKLC_01667 6.47e-244 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
JIOHCKLC_01671 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JIOHCKLC_01672 2.54e-211 - - - K - - - transcriptional regulator (lysR family)
JIOHCKLC_01673 3.31e-238 coiA - - S ko:K06198 - ko00000 Competence protein
JIOHCKLC_01674 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
JIOHCKLC_01675 2.39e-164 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
JIOHCKLC_01676 6.55e-237 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
JIOHCKLC_01677 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JIOHCKLC_01678 1.67e-29 - - - M - - - GBS Bsp-like repeat
JIOHCKLC_01679 1.94e-186 - - - M - - - GBS Bsp-like repeat
JIOHCKLC_01680 2.79e-158 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
JIOHCKLC_01681 1.29e-186 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JIOHCKLC_01682 1.17e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
JIOHCKLC_01683 1.12e-242 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JIOHCKLC_01684 4.21e-285 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JIOHCKLC_01685 2.56e-164 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
JIOHCKLC_01686 9.21e-267 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
JIOHCKLC_01687 6.7e-189 icaB - - G - - - deacetylase
JIOHCKLC_01688 7.29e-304 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
JIOHCKLC_01689 3.69e-198 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JIOHCKLC_01690 1.32e-195 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
JIOHCKLC_01692 2.62e-17 coiA - - S ko:K06198 - ko00000 Competence protein
JIOHCKLC_01693 4.13e-143 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JIOHCKLC_01694 7.34e-63 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JIOHCKLC_01695 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JIOHCKLC_01696 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JIOHCKLC_01697 4.44e-160 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
JIOHCKLC_01698 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
JIOHCKLC_01699 3.66e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JIOHCKLC_01700 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JIOHCKLC_01701 9.48e-204 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JIOHCKLC_01702 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JIOHCKLC_01703 6.23e-97 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
JIOHCKLC_01704 3.51e-293 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
JIOHCKLC_01705 7.86e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JIOHCKLC_01706 6.58e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JIOHCKLC_01707 1.19e-142 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JIOHCKLC_01708 7.84e-207 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
JIOHCKLC_01709 3.89e-175 yaaT - - S - - - stage 0 sporulation protein
JIOHCKLC_01710 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
JIOHCKLC_01711 2.42e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JIOHCKLC_01712 1.39e-297 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
JIOHCKLC_01713 3.22e-71 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
JIOHCKLC_01714 7.94e-141 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
JIOHCKLC_01715 3.41e-192 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
JIOHCKLC_01716 3.54e-88 phoU_1 - - P ko:K03324 - ko00000,ko02000 sodium-dependent phosphate transmembrane transporter activity
JIOHCKLC_01717 8.41e-282 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
JIOHCKLC_01718 2.07e-71 - - - - - - - -
JIOHCKLC_01719 2.36e-35 - - - - - - - -
JIOHCKLC_01720 8.89e-80 - - - - - - - -
JIOHCKLC_01721 2.41e-79 - - - S - - - membrane
JIOHCKLC_01722 2.48e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
JIOHCKLC_01723 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
JIOHCKLC_01724 4.07e-52 ynzC - - S - - - UPF0291 protein
JIOHCKLC_01725 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
JIOHCKLC_01727 3.5e-92 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_01728 6.06e-99 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_01729 7.69e-103 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
JIOHCKLC_01730 1.5e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JIOHCKLC_01734 1.36e-215 lysR - - K - - - transcriptional regulator (lysR family)
JIOHCKLC_01735 1.4e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JIOHCKLC_01736 1.71e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
JIOHCKLC_01737 6.68e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JIOHCKLC_01738 2.02e-288 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
JIOHCKLC_01739 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
JIOHCKLC_01740 9.61e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
JIOHCKLC_01741 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
JIOHCKLC_01742 4.44e-173 - - - S - - - Putative SAM-dependent methyltransferase
JIOHCKLC_01743 1.04e-46 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JIOHCKLC_01744 1.1e-46 - - - V - - - efflux transmembrane transporter activity
JIOHCKLC_01745 3.93e-47 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
JIOHCKLC_01746 3.74e-34 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 efflux transmembrane transporter activity
JIOHCKLC_01747 3.14e-101 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JIOHCKLC_01748 2.46e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JIOHCKLC_01750 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_01751 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
JIOHCKLC_01752 4.12e-253 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JIOHCKLC_01753 7.37e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JIOHCKLC_01754 3.52e-292 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
JIOHCKLC_01755 1.69e-169 rr02 - - KT - - - response regulator
JIOHCKLC_01756 6.56e-279 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JIOHCKLC_01757 2.86e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
JIOHCKLC_01758 1.79e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
JIOHCKLC_01759 6.51e-249 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
JIOHCKLC_01760 2.68e-39 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
JIOHCKLC_01762 2.6e-183 - - - F - - - Phosphorylase superfamily
JIOHCKLC_01763 4.5e-73 - - - S - - - VIT family
JIOHCKLC_01764 1.2e-55 - - - S - - - VIT family
JIOHCKLC_01765 3.68e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
JIOHCKLC_01766 1.83e-280 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JIOHCKLC_01767 1.29e-24 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
JIOHCKLC_01768 2.16e-57 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
JIOHCKLC_01769 1.9e-316 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JIOHCKLC_01770 3.96e-137 - - - J ko:K09962 - ko00000 protein conserved in bacteria
JIOHCKLC_01771 2.99e-191 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
JIOHCKLC_01772 6.82e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
JIOHCKLC_01773 1.5e-231 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
JIOHCKLC_01774 9.21e-244 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JIOHCKLC_01775 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JIOHCKLC_01776 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
JIOHCKLC_01777 1.47e-41 - - - - - - - -
JIOHCKLC_01778 3.48e-150 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JIOHCKLC_01780 9.15e-10 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
JIOHCKLC_01781 4.12e-59 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
JIOHCKLC_01782 7.8e-06 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
JIOHCKLC_01783 2.09e-244 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
JIOHCKLC_01784 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
JIOHCKLC_01785 5.47e-29 - - - - - - - -
JIOHCKLC_01786 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JIOHCKLC_01787 1.35e-60 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JIOHCKLC_01788 6.04e-89 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JIOHCKLC_01789 2.35e-211 - - - S - - - Protein of unknown function (DUF3114)
JIOHCKLC_01790 9.03e-29 - - - S - - - Protein of unknown function (DUF3114)
JIOHCKLC_01791 1.01e-151 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
JIOHCKLC_01792 3.81e-35 - - - K - - - hmm pf08876
JIOHCKLC_01793 1.76e-297 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
JIOHCKLC_01794 3.13e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
JIOHCKLC_01795 5.15e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JIOHCKLC_01796 7.02e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JIOHCKLC_01797 2.97e-30 - - - - - - - -
JIOHCKLC_01798 8.89e-288 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JIOHCKLC_01799 1.93e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
JIOHCKLC_01800 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
JIOHCKLC_01801 8.67e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
JIOHCKLC_01802 5.22e-41 - - - S - - - Domain of unknown function (DUF1912)
JIOHCKLC_01803 1.1e-20 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
JIOHCKLC_01804 3.01e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JIOHCKLC_01805 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JIOHCKLC_01806 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JIOHCKLC_01807 4.29e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
JIOHCKLC_01808 3.44e-22 - - - S - - - Protein of unknown function (DUF2969)
JIOHCKLC_01811 1.44e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
JIOHCKLC_01814 6.33e-132 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
JIOHCKLC_01815 2.5e-90 - - - M - - - Pfam SNARE associated Golgi protein
JIOHCKLC_01816 3.82e-295 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
JIOHCKLC_01817 1.83e-74 - - - S - - - oxidoreductase
JIOHCKLC_01818 2.73e-84 - - - S - - - oxidoreductase
JIOHCKLC_01819 1.29e-64 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
JIOHCKLC_01820 7.82e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
JIOHCKLC_01821 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
JIOHCKLC_01822 1.06e-233 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JIOHCKLC_01823 1.15e-47 ykuJ - - S - - - protein conserved in bacteria
JIOHCKLC_01824 3.24e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
JIOHCKLC_01825 4.45e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
JIOHCKLC_01826 7.39e-103 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
JIOHCKLC_01827 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
JIOHCKLC_01828 9.87e-12 - - - - - - - -
JIOHCKLC_01829 1.27e-135 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JIOHCKLC_01830 7.29e-61 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
JIOHCKLC_01831 2.87e-47 yugF - - I - - - carboxylic ester hydrolase activity
JIOHCKLC_01832 5.04e-29 - - - I - - - Alpha/beta hydrolase family
JIOHCKLC_01833 8.45e-203 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JIOHCKLC_01834 2.91e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JIOHCKLC_01835 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
JIOHCKLC_01836 7.55e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JIOHCKLC_01837 3.61e-84 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
JIOHCKLC_01838 1.21e-69 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
JIOHCKLC_01839 2.18e-112 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JIOHCKLC_01840 9.96e-85 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
JIOHCKLC_01841 1.16e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JIOHCKLC_01842 1.16e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JIOHCKLC_01843 4.45e-136 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JIOHCKLC_01844 2.94e-281 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
JIOHCKLC_01845 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
JIOHCKLC_01846 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JIOHCKLC_01847 5.69e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JIOHCKLC_01848 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JIOHCKLC_01849 1.08e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
JIOHCKLC_01850 7e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
JIOHCKLC_01851 1.34e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
JIOHCKLC_01852 2.03e-35 XK27_07735 - - S - - - YjbR
JIOHCKLC_01853 6.38e-130 yyaQ - - V - - - Protein conserved in bacteria
JIOHCKLC_01854 6.29e-117 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
JIOHCKLC_01855 4.6e-136 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
JIOHCKLC_01856 1.03e-101 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
JIOHCKLC_01857 1.75e-314 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JIOHCKLC_01858 2.22e-34 WQ51_00785 - - - - - - -
JIOHCKLC_01859 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
JIOHCKLC_01860 1.45e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
JIOHCKLC_01861 8.04e-158 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JIOHCKLC_01862 4.21e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JIOHCKLC_01863 1.24e-258 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JIOHCKLC_01864 1.29e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JIOHCKLC_01865 1.92e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
JIOHCKLC_01866 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
JIOHCKLC_01867 6.06e-223 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
JIOHCKLC_01868 1.77e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JIOHCKLC_01869 2.28e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JIOHCKLC_01870 3.43e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
JIOHCKLC_01871 0.0 msrR - - K - - - Transcriptional regulator
JIOHCKLC_01872 7.66e-191 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
JIOHCKLC_01873 3.83e-257 - - - I - - - acyl-CoA dehydrogenase
JIOHCKLC_01874 5.21e-126 mip - - S - - - hydroperoxide reductase activity
JIOHCKLC_01875 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JIOHCKLC_01876 9.57e-132 - - - - - - - -
JIOHCKLC_01877 2.13e-44 - - - K - - - Cro/C1-type HTH DNA-binding domain
JIOHCKLC_01878 4.96e-59 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
JIOHCKLC_01880 4.59e-124 - - - - - - - -
JIOHCKLC_01881 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JIOHCKLC_01882 1.61e-221 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JIOHCKLC_01883 8.44e-71 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JIOHCKLC_01884 6.13e-236 - - - S - - - CRISPR-associated protein Csn2 subfamily St
JIOHCKLC_01885 4.65e-189 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
JIOHCKLC_01886 4.63e-199 XK27_03015 - - S ko:K07089 - ko00000 permease
JIOHCKLC_01888 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
JIOHCKLC_01889 1.45e-55 WQ51_05770 - - KT - - - PspC domain
JIOHCKLC_01890 2.36e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JIOHCKLC_01891 1.51e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JIOHCKLC_01892 1.14e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JIOHCKLC_01893 1.66e-91 ytxH - - S - - - General stress protein
JIOHCKLC_01895 1.23e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
JIOHCKLC_01896 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
JIOHCKLC_01897 3.62e-60 - - - S - - - CHY zinc finger
JIOHCKLC_01898 2.67e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
JIOHCKLC_01900 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
JIOHCKLC_01901 3.16e-297 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
JIOHCKLC_01902 2.07e-18 - - - - - - - -
JIOHCKLC_01903 1.97e-264 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
JIOHCKLC_01904 8.02e-285 - - - L - - - DNA mismatch repair enzyme MutH
JIOHCKLC_01905 7.82e-40 - - - S - - - SIR2-like domain
JIOHCKLC_01906 1.34e-39 - - - S - - - SIR2-like domain
JIOHCKLC_01907 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
JIOHCKLC_01908 2.07e-211 - - - M - - - LysM domain
JIOHCKLC_01909 2.16e-29 - - - - - - - -
JIOHCKLC_01910 3.26e-224 - - - S ko:K07025 - ko00000 hydrolase
JIOHCKLC_01911 1.02e-149 pgm - - G - - - Phosphoglycerate mutase
JIOHCKLC_01912 2.49e-105 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JIOHCKLC_01913 9.89e-197 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
JIOHCKLC_01914 1.14e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
JIOHCKLC_01915 2.83e-145 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JIOHCKLC_01916 4.51e-14 - - - S - - - Protein of unknown function (DUF2974)
JIOHCKLC_01917 1.03e-27 - - - S - - - Protein of unknown function (DUF2974)
JIOHCKLC_01918 2.19e-122 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
JIOHCKLC_01919 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
JIOHCKLC_01920 1.79e-199 - - - S - - - Bacteriophage abortive infection AbiH
JIOHCKLC_01922 4.02e-164 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
JIOHCKLC_01923 8.71e-75 - - - S - - - Phage derived protein Gp49-like (DUF891)
JIOHCKLC_01924 1.8e-56 - - - K - - - Helix-turn-helix domain
JIOHCKLC_01925 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
JIOHCKLC_01926 7.65e-61 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
JIOHCKLC_01927 1.77e-26 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
JIOHCKLC_01928 3.34e-175 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
JIOHCKLC_01929 1.04e-118 lemA - - S ko:K03744 - ko00000 LemA family
JIOHCKLC_01930 3.15e-185 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
JIOHCKLC_01931 8.61e-97 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
JIOHCKLC_01932 2.18e-73 - - - S - - - Domain of unknown function (DUF4430)
JIOHCKLC_01933 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JIOHCKLC_01934 2.71e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
JIOHCKLC_01935 6.73e-145 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)