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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKECNGDP_00001	1.46e-126	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HKECNGDP_00002	5.08e-276	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HKECNGDP_00003	1.96e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HKECNGDP_00004	6.27e-106	yuaE	-	-	S	-	-	-	DinB superfamily
HKECNGDP_00005	6.79e-141	-	-	-	S	-	-	-	MOSC domain
HKECNGDP_00006	5.82e-289	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HKECNGDP_00007	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKECNGDP_00008	7.09e-125	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HKECNGDP_00009	2.03e-122	yuaB	-	-	-	-	-	-	-
HKECNGDP_00010	6.13e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HKECNGDP_00011	6.61e-194	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKECNGDP_00012	2.94e-282	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKECNGDP_00013	9.53e-160	-	-	-	G	-	-	-	Cupin
HKECNGDP_00014	1.63e-14	yjcN	-	-	-	-	-	-	-
HKECNGDP_00016	9.34e-21	-	-	-	-	-	-	-	-
HKECNGDP_00019	8.26e-175	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HKECNGDP_00020	2.11e-19	-	-	-	-	-	-	-	-
HKECNGDP_00021	4.84e-52	-	-	-	-	-	-	-	-
HKECNGDP_00023	6.56e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKECNGDP_00024	6.02e-252	yubA	-	-	S	-	-	-	transporter activity
HKECNGDP_00025	5.49e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HKECNGDP_00026	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKECNGDP_00027	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HKECNGDP_00028	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HKECNGDP_00029	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HKECNGDP_00030	2.39e-299	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HKECNGDP_00031	2.22e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HKECNGDP_00032	1.61e-55	-	-	-	-	-	-	-	-
HKECNGDP_00033	3.88e-240	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HKECNGDP_00034	2.69e-98	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HKECNGDP_00035	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKECNGDP_00036	3.29e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HKECNGDP_00037	9.68e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HKECNGDP_00038	1.24e-22	-	-	-	-	-	-	-	-
HKECNGDP_00039	4.93e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HKECNGDP_00040	4.84e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HKECNGDP_00041	8.53e-95	yugN	-	-	S	-	-	-	YugN-like family
HKECNGDP_00043	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKECNGDP_00044	1.95e-133	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HKECNGDP_00045	1.77e-151	ycaC	-	-	Q	-	-	-	Isochorismatase family
HKECNGDP_00046	7.9e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HKECNGDP_00047	6.7e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HKECNGDP_00048	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HKECNGDP_00049	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HKECNGDP_00050	1.68e-266	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HKECNGDP_00051	1.07e-108	alaR	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00052	1.64e-199	yugF	-	-	I	-	-	-	Hydrolase
HKECNGDP_00053	4.25e-55	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HKECNGDP_00054	2.73e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKECNGDP_00055	1.81e-292	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00056	6.88e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HKECNGDP_00057	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HKECNGDP_00058	2.25e-264	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HKECNGDP_00059	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HKECNGDP_00060	2.62e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00061	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HKECNGDP_00062	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HKECNGDP_00063	5.63e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HKECNGDP_00064	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HKECNGDP_00065	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_00066	7.78e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKECNGDP_00067	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKECNGDP_00069	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKECNGDP_00070	5.39e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKECNGDP_00071	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKECNGDP_00072	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKECNGDP_00073	6.08e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKECNGDP_00074	1.91e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKECNGDP_00075	4.2e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HKECNGDP_00076	8.4e-85	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HKECNGDP_00077	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKECNGDP_00078	1.36e-93	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00079	1.39e-241	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00081	5.17e-124	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HKECNGDP_00082	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
HKECNGDP_00083	1.79e-68	yuzC	-	-	-	-	-	-	-
HKECNGDP_00084	6.86e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HKECNGDP_00085	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKECNGDP_00086	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HKECNGDP_00087	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKECNGDP_00088	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
HKECNGDP_00089	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HKECNGDP_00090	1.88e-238	yueF	-	-	S	-	-	-	transporter activity
HKECNGDP_00091	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HKECNGDP_00092	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HKECNGDP_00093	2.29e-166	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_00094	3.4e-99	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HKECNGDP_00095	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HKECNGDP_00096	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HKECNGDP_00097	1.38e-276	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HKECNGDP_00098	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HKECNGDP_00099	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HKECNGDP_00100	5.19e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
HKECNGDP_00101	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HKECNGDP_00102	5.08e-170	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HKECNGDP_00103	1.91e-46	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HKECNGDP_00104	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_00105	1.95e-220	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HKECNGDP_00106	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HKECNGDP_00107	2.74e-286	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HKECNGDP_00108	2.47e-171	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_00109	1.79e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HKECNGDP_00110	1.87e-154	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HKECNGDP_00111	3.73e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HKECNGDP_00112	8.19e-276	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HKECNGDP_00113	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKECNGDP_00114	4.99e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HKECNGDP_00115	7.23e-155	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00116	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
HKECNGDP_00117	3.42e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKECNGDP_00118	2.95e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HKECNGDP_00120	4.7e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKECNGDP_00121	5.68e-40	-	-	-	-	-	-	-	-
HKECNGDP_00122	5.92e-93	-	-	-	CP	-	-	-	Membrane
HKECNGDP_00123	1.18e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKECNGDP_00125	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
HKECNGDP_00127	3.41e-121	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HKECNGDP_00128	3.14e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_00129	1.38e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HKECNGDP_00130	3.2e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKECNGDP_00131	1.49e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKECNGDP_00132	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HKECNGDP_00133	8.47e-266	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKECNGDP_00134	1.57e-71	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00135	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HKECNGDP_00136	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HKECNGDP_00137	7.89e-216	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKECNGDP_00138	2.8e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HKECNGDP_00139	1.43e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKECNGDP_00140	1.55e-250	yutH	-	-	S	-	-	-	Spore coat protein
HKECNGDP_00141	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HKECNGDP_00142	4.31e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKECNGDP_00143	2.67e-96	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HKECNGDP_00144	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00145	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKECNGDP_00146	3.92e-249	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HKECNGDP_00147	4.76e-168	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HKECNGDP_00148	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKECNGDP_00149	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKECNGDP_00150	6.03e-216	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HKECNGDP_00151	5.25e-81	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HKECNGDP_00152	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HKECNGDP_00153	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HKECNGDP_00155	2.89e-272	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_00156	3.44e-301	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HKECNGDP_00157	3.28e-297	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HKECNGDP_00158	7.06e-218	bsn	-	-	L	-	-	-	Ribonuclease
HKECNGDP_00159	1.35e-264	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_00160	2.8e-171	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HKECNGDP_00161	8.81e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HKECNGDP_00162	8.84e-210	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HKECNGDP_00163	5.26e-203	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKECNGDP_00164	3.67e-313	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HKECNGDP_00165	2.72e-237	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HKECNGDP_00166	4.05e-213	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKECNGDP_00168	5.4e-95	-	-	-	-	-	-	-	-
HKECNGDP_00169	9.84e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HKECNGDP_00171	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HKECNGDP_00172	1.83e-259	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HKECNGDP_00173	6.45e-158	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HKECNGDP_00174	1.77e-103	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HKECNGDP_00175	6.19e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HKECNGDP_00176	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HKECNGDP_00177	1.26e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HKECNGDP_00178	2.69e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKECNGDP_00179	2.48e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HKECNGDP_00180	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKECNGDP_00181	2.54e-84	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKECNGDP_00182	1.82e-186	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HKECNGDP_00183	2.96e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HKECNGDP_00184	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKECNGDP_00185	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HKECNGDP_00186	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
HKECNGDP_00187	1.79e-81	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HKECNGDP_00188	3.1e-55	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HKECNGDP_00189	1.98e-83	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HKECNGDP_00190	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HKECNGDP_00191	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HKECNGDP_00192	7.74e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HKECNGDP_00193	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HKECNGDP_00194	2.54e-213	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HKECNGDP_00195	1.48e-263	yusP	-	-	P	-	-	-	Major facilitator superfamily
HKECNGDP_00196	3.2e-58	-	-	-	-	-	-	-	-
HKECNGDP_00197	5.21e-62	yusN	-	-	M	-	-	-	Coat F domain
HKECNGDP_00198	3.93e-91	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HKECNGDP_00199	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HKECNGDP_00200	9.82e-203	-	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00201	4.31e-178	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HKECNGDP_00202	3.45e-240	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKECNGDP_00203	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HKECNGDP_00204	3.69e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKECNGDP_00205	1.32e-60	-	-	-	S	-	-	-	YusW-like protein
HKECNGDP_00206	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HKECNGDP_00207	5.7e-199	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_00208	4.12e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKECNGDP_00209	1.38e-307	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKECNGDP_00210	1.83e-163	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_00211	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00212	4.63e-33	-	-	-	-	-	-	-	-
HKECNGDP_00213	3.11e-201	yuxN	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00214	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKECNGDP_00215	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HKECNGDP_00216	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HKECNGDP_00217	1.98e-240	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HKECNGDP_00218	1.02e-258	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HKECNGDP_00219	1.02e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKECNGDP_00220	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00221	5.33e-160	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HKECNGDP_00222	5.82e-192	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HKECNGDP_00223	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HKECNGDP_00224	1.62e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HKECNGDP_00225	3.37e-290	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_00226	4.59e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HKECNGDP_00227	1.32e-289	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HKECNGDP_00228	1.38e-231	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_00229	1.16e-215	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKECNGDP_00230	4.1e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_00231	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HKECNGDP_00232	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HKECNGDP_00233	2.7e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_00234	1.67e-50	-	-	-	-	-	-	-	-
HKECNGDP_00235	1.31e-133	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HKECNGDP_00236	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
HKECNGDP_00237	3.11e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HKECNGDP_00238	8.36e-89	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HKECNGDP_00239	9.78e-189	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKECNGDP_00240	2.76e-225	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_00241	1.56e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_00242	3.67e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKECNGDP_00243	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HKECNGDP_00244	1.29e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HKECNGDP_00245	1.01e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HKECNGDP_00246	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HKECNGDP_00247	2.44e-214	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HKECNGDP_00248	4.78e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HKECNGDP_00249	1.57e-122	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HKECNGDP_00250	2.05e-146	yfiK	-	-	K	-	-	-	Regulator
HKECNGDP_00251	3.36e-250	-	-	-	T	-	-	-	Histidine kinase
HKECNGDP_00252	1.42e-219	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HKECNGDP_00253	4.96e-249	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKECNGDP_00254	6.19e-263	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HKECNGDP_00255	7.23e-200	yvgN	-	-	S	-	-	-	reductase
HKECNGDP_00256	5.61e-113	yvgO	-	-	-	-	-	-	-
HKECNGDP_00257	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HKECNGDP_00258	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HKECNGDP_00259	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKECNGDP_00260	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKECNGDP_00261	6.36e-130	yvgT	-	-	S	-	-	-	membrane
HKECNGDP_00262	8.08e-192	-	-	-	S	-	-	-	Metallo-peptidase family M12
HKECNGDP_00263	7.48e-96	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HKECNGDP_00264	9.54e-140	bdbD	-	-	O	-	-	-	Thioredoxin
HKECNGDP_00265	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HKECNGDP_00266	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKECNGDP_00267	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HKECNGDP_00268	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HKECNGDP_00269	1e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HKECNGDP_00270	5.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKECNGDP_00271	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_00272	4.82e-60	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HKECNGDP_00273	3.7e-234	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_00274	9e-181	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HKECNGDP_00275	6.77e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKECNGDP_00276	6.25e-158	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKECNGDP_00277	8.69e-189	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKECNGDP_00278	2.06e-168	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKECNGDP_00279	3.16e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKECNGDP_00280	4.65e-205	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HKECNGDP_00281	1.6e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_00282	4.14e-66	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HKECNGDP_00284	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HKECNGDP_00285	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKECNGDP_00286	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HKECNGDP_00287	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HKECNGDP_00288	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
HKECNGDP_00289	2.73e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HKECNGDP_00290	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HKECNGDP_00291	2.97e-70	yvaP	-	-	K	-	-	-	transcriptional
HKECNGDP_00292	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HKECNGDP_00293	6.66e-159	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKECNGDP_00294	2.29e-177	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HKECNGDP_00295	1.53e-160	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HKECNGDP_00296	9.33e-163	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_00297	1.72e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HKECNGDP_00298	2.67e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKECNGDP_00299	1.96e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HKECNGDP_00300	6.74e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKECNGDP_00301	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HKECNGDP_00302	2.64e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HKECNGDP_00303	3.25e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKECNGDP_00304	1.61e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HKECNGDP_00305	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKECNGDP_00306	1.01e-129	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HKECNGDP_00307	1.88e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HKECNGDP_00308	3.78e-157	yvbI	-	-	M	-	-	-	Membrane
HKECNGDP_00309	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKECNGDP_00310	1.11e-106	yvbK	-	-	K	-	-	-	acetyltransferase
HKECNGDP_00311	4.64e-271	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKECNGDP_00312	1.33e-226	-	-	-	-	-	-	-	-
HKECNGDP_00313	5.24e-161	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HKECNGDP_00314	2.89e-185	-	-	-	C	-	-	-	WbqC-like protein family
HKECNGDP_00315	2.26e-191	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
HKECNGDP_00316	3.99e-296	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HKECNGDP_00317	3.49e-219	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HKECNGDP_00318	4.83e-278	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HKECNGDP_00319	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKECNGDP_00320	5.09e-305	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HKECNGDP_00321	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKECNGDP_00322	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HKECNGDP_00323	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKECNGDP_00324	3.98e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKECNGDP_00325	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKECNGDP_00326	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKECNGDP_00328	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKECNGDP_00329	6.68e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HKECNGDP_00330	5.33e-243	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_00332	1.51e-200	yvbU	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00333	5.22e-203	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HKECNGDP_00334	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HKECNGDP_00335	0.0	-	-	-	-	-	-	-	-
HKECNGDP_00336	3.55e-231	yhjM	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00337	1.55e-149	-	-	-	S	ko:K07149	-	ko00000	Membrane
HKECNGDP_00338	1.79e-214	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HKECNGDP_00339	2.58e-193	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
HKECNGDP_00340	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKECNGDP_00341	1.37e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HKECNGDP_00342	3.53e-173	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKECNGDP_00343	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HKECNGDP_00344	2.14e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKECNGDP_00345	4.54e-284	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKECNGDP_00346	3.1e-156	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HKECNGDP_00347	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKECNGDP_00348	2.39e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HKECNGDP_00349	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
HKECNGDP_00350	8.48e-242	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HKECNGDP_00351	2.72e-282	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HKECNGDP_00352	2.19e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HKECNGDP_00353	1.92e-140	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKECNGDP_00354	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKECNGDP_00355	4.26e-249	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HKECNGDP_00356	4.49e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HKECNGDP_00357	1.08e-247	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HKECNGDP_00358	4.89e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HKECNGDP_00359	6.06e-273	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKECNGDP_00360	2.74e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HKECNGDP_00361	4.12e-276	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HKECNGDP_00362	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HKECNGDP_00363	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HKECNGDP_00364	1.66e-155	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HKECNGDP_00365	6.96e-100	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HKECNGDP_00366	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HKECNGDP_00367	4.68e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HKECNGDP_00368	3.57e-144	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HKECNGDP_00369	1.15e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKECNGDP_00370	2.47e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HKECNGDP_00371	2.94e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HKECNGDP_00372	2.86e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HKECNGDP_00373	2.54e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HKECNGDP_00375	3.97e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HKECNGDP_00376	2.13e-293	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HKECNGDP_00377	4.26e-51	-	-	-	-	-	-	-	-
HKECNGDP_00378	3.58e-118	yybG	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HKECNGDP_00379	6.43e-30	-	-	-	L	-	-	-	Phage integrase family
HKECNGDP_00381	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKECNGDP_00382	8.17e-285	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HKECNGDP_00383	6.39e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HKECNGDP_00384	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKECNGDP_00385	1.36e-209	yraN	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00386	2.68e-275	yraM	-	-	S	-	-	-	PrpF protein
HKECNGDP_00387	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HKECNGDP_00388	1.32e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKECNGDP_00389	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HKECNGDP_00390	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HKECNGDP_00391	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HKECNGDP_00392	3.56e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKECNGDP_00393	2.26e-104	-	-	-	M	-	-	-	Ribonuclease
HKECNGDP_00394	2.32e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HKECNGDP_00395	3.23e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HKECNGDP_00396	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKECNGDP_00397	2.12e-224	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKECNGDP_00398	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKECNGDP_00399	2.98e-112	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKECNGDP_00400	4.99e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKECNGDP_00401	7.1e-202	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HKECNGDP_00402	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HKECNGDP_00403	3.35e-246	sasA	-	-	T	-	-	-	Histidine kinase
HKECNGDP_00404	3.99e-158	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_00405	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKECNGDP_00406	4.9e-145	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HKECNGDP_00407	1.38e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKECNGDP_00408	7.97e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKECNGDP_00409	4e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKECNGDP_00410	6.76e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HKECNGDP_00411	1.11e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKECNGDP_00412	2.14e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKECNGDP_00413	1.42e-268	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKECNGDP_00414	1.19e-176	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HKECNGDP_00415	1.07e-115	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HKECNGDP_00416	2.24e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HKECNGDP_00417	8.74e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKECNGDP_00418	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKECNGDP_00419	4.06e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKECNGDP_00420	9.04e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKECNGDP_00421	8.67e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HKECNGDP_00422	8.92e-136	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HKECNGDP_00423	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HKECNGDP_00424	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HKECNGDP_00425	4.01e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HKECNGDP_00426	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
HKECNGDP_00427	4.87e-66	yvlA	-	-	-	-	-	-	-
HKECNGDP_00428	1.78e-51	yvkN	-	-	-	-	-	-	-
HKECNGDP_00429	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKECNGDP_00430	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKECNGDP_00431	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00432	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HKECNGDP_00433	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00434	1.45e-298	yvkA	-	-	P	-	-	-	-transporter
HKECNGDP_00435	8.78e-34	-	-	-	Q	-	-	-	Thioesterase domain
HKECNGDP_00437	5.49e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKECNGDP_00438	2.93e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKECNGDP_00439	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HKECNGDP_00440	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKECNGDP_00441	2.23e-300	ywoF	-	-	P	-	-	-	Right handed beta helix region
HKECNGDP_00442	7.34e-197	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKECNGDP_00443	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HKECNGDP_00444	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HKECNGDP_00445	4.82e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HKECNGDP_00446	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKECNGDP_00447	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKECNGDP_00448	3.94e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKECNGDP_00449	1.35e-89	-	-	-	-	-	-	-	-
HKECNGDP_00450	3.91e-11	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HKECNGDP_00451	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HKECNGDP_00452	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HKECNGDP_00453	8.17e-153	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKECNGDP_00454	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HKECNGDP_00455	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HKECNGDP_00456	2.8e-108	yviE	-	-	-	-	-	-	-
HKECNGDP_00457	1.2e-208	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HKECNGDP_00458	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HKECNGDP_00459	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
HKECNGDP_00460	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HKECNGDP_00461	1.1e-97	yvyF	-	-	S	-	-	-	flagellar protein
HKECNGDP_00462	2.44e-86	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HKECNGDP_00463	2.14e-58	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HKECNGDP_00464	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKECNGDP_00465	1.46e-202	degV	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00466	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKECNGDP_00467	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HKECNGDP_00468	2.94e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HKECNGDP_00469	1.5e-239	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00470	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HKECNGDP_00471	9.83e-305	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HKECNGDP_00472	2.82e-185	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HKECNGDP_00473	6.04e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HKECNGDP_00474	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HKECNGDP_00475	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKECNGDP_00476	4.74e-287	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HKECNGDP_00477	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKECNGDP_00478	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKECNGDP_00479	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HKECNGDP_00480	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HKECNGDP_00481	3.22e-65	-	-	-	-	-	-	-	-
HKECNGDP_00482	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HKECNGDP_00483	2.67e-272	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKECNGDP_00484	7.57e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKECNGDP_00485	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKECNGDP_00486	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HKECNGDP_00487	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKECNGDP_00488	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKECNGDP_00489	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HKECNGDP_00490	4.31e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKECNGDP_00491	2.6e-279	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKECNGDP_00492	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKECNGDP_00493	4.53e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKECNGDP_00494	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HKECNGDP_00495	1.28e-253	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HKECNGDP_00496	8.96e-274	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HKECNGDP_00497	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
HKECNGDP_00498	3.45e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKECNGDP_00499	9.77e-231	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00500	1.51e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HKECNGDP_00501	6.38e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HKECNGDP_00502	1.35e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKECNGDP_00503	4.04e-29	ywtC	-	-	-	-	-	-	-
HKECNGDP_00504	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HKECNGDP_00505	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HKECNGDP_00506	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HKECNGDP_00507	2.54e-241	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HKECNGDP_00508	7.28e-246	-	-	-	E	-	-	-	Spore germination protein
HKECNGDP_00509	9.78e-258	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HKECNGDP_00510	4.28e-228	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HKECNGDP_00511	2.94e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKECNGDP_00512	4.8e-86	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKECNGDP_00513	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HKECNGDP_00514	6.25e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKECNGDP_00515	2.82e-207	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HKECNGDP_00516	3.54e-117	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HKECNGDP_00517	2.13e-124	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HKECNGDP_00518	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HKECNGDP_00519	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKECNGDP_00520	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
HKECNGDP_00522	1.27e-307	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKECNGDP_00523	3.43e-163	ywrJ	-	-	-	-	-	-	-
HKECNGDP_00524	4.32e-184	cotB	-	-	-	ko:K06325	-	ko00000	-
HKECNGDP_00525	5.57e-271	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HKECNGDP_00526	8.29e-19	-	-	-	-	-	-	-	-
HKECNGDP_00527	8.12e-144	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKECNGDP_00529	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HKECNGDP_00530	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HKECNGDP_00531	2.96e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HKECNGDP_00532	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HKECNGDP_00533	1.67e-163	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HKECNGDP_00535	2.04e-301	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HKECNGDP_00536	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HKECNGDP_00539	9.83e-191	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HKECNGDP_00540	2.14e-314	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKECNGDP_00541	2.13e-181	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HKECNGDP_00542	7.7e-158	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HKECNGDP_00543	1.78e-70	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HKECNGDP_00544	1.64e-64	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HKECNGDP_00545	1.74e-21	-	-	-	-	-	-	-	-
HKECNGDP_00546	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HKECNGDP_00547	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKECNGDP_00548	4.34e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HKECNGDP_00549	1.32e-178	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKECNGDP_00550	5.13e-77	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HKECNGDP_00551	4.49e-82	ywpG	-	-	-	-	-	-	-
HKECNGDP_00552	5.31e-90	ywpF	-	-	S	-	-	-	YwpF-like protein
HKECNGDP_00553	7.6e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKECNGDP_00554	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKECNGDP_00555	1.1e-256	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HKECNGDP_00556	3.27e-188	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HKECNGDP_00557	1.03e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HKECNGDP_00558	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HKECNGDP_00559	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HKECNGDP_00560	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
HKECNGDP_00561	2.37e-271	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_00562	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HKECNGDP_00563	5.42e-310	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HKECNGDP_00564	1.09e-130	yjgF	-	-	Q	-	-	-	Isochorismatase family
HKECNGDP_00565	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HKECNGDP_00566	1.29e-76	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HKECNGDP_00567	1.72e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKECNGDP_00568	8.23e-132	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HKECNGDP_00569	1.56e-93	ywnJ	-	-	S	-	-	-	VanZ like family
HKECNGDP_00570	1.31e-188	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HKECNGDP_00571	1.6e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HKECNGDP_00573	1.48e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HKECNGDP_00574	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKECNGDP_00575	5.66e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HKECNGDP_00576	4.36e-156	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HKECNGDP_00578	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00579	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKECNGDP_00580	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HKECNGDP_00581	2.86e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HKECNGDP_00582	2.94e-17	csbD	-	-	K	-	-	-	CsbD-like
HKECNGDP_00583	8.64e-107	ywmF	-	-	S	-	-	-	Peptidase M50
HKECNGDP_00584	2.21e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HKECNGDP_00585	5.35e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HKECNGDP_00586	2.13e-185	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HKECNGDP_00588	1.5e-158	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HKECNGDP_00589	1.42e-148	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HKECNGDP_00590	2.01e-242	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HKECNGDP_00591	2.87e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKECNGDP_00592	6.59e-172	ywmB	-	-	S	-	-	-	TATA-box binding
HKECNGDP_00593	2.25e-45	ywzB	-	-	S	-	-	-	membrane
HKECNGDP_00594	1.76e-118	ywmA	-	-	-	-	-	-	-
HKECNGDP_00595	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKECNGDP_00596	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKECNGDP_00597	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKECNGDP_00598	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKECNGDP_00599	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKECNGDP_00600	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKECNGDP_00601	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKECNGDP_00602	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKECNGDP_00603	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HKECNGDP_00604	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKECNGDP_00605	1.7e-300	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKECNGDP_00606	1.23e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HKECNGDP_00607	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HKECNGDP_00608	2.08e-101	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKECNGDP_00609	1.17e-119	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HKECNGDP_00610	1.86e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKECNGDP_00611	2.98e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HKECNGDP_00612	6.57e-153	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HKECNGDP_00613	2.08e-79	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HKECNGDP_00615	1.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKECNGDP_00616	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKECNGDP_00617	9.07e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKECNGDP_00618	1.48e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HKECNGDP_00619	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKECNGDP_00620	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HKECNGDP_00621	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKECNGDP_00622	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HKECNGDP_00623	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKECNGDP_00624	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HKECNGDP_00625	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKECNGDP_00626	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKECNGDP_00627	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HKECNGDP_00628	4.37e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HKECNGDP_00629	8.11e-121	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HKECNGDP_00630	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKECNGDP_00631	6.53e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKECNGDP_00632	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HKECNGDP_00633	2.84e-284	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HKECNGDP_00634	1.83e-231	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HKECNGDP_00635	1.13e-58	ywjC	-	-	-	-	-	-	-
HKECNGDP_00636	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKECNGDP_00637	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKECNGDP_00638	1.43e-134	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKECNGDP_00639	4.85e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HKECNGDP_00640	1.88e-125	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HKECNGDP_00641	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HKECNGDP_00642	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKECNGDP_00643	2.49e-110	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HKECNGDP_00644	2.93e-176	ywiC	-	-	S	-	-	-	YwiC-like protein
HKECNGDP_00645	3.01e-164	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HKECNGDP_00646	1.05e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HKECNGDP_00647	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKECNGDP_00648	1.14e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00650	2.22e-311	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HKECNGDP_00651	1.82e-272	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HKECNGDP_00652	5.77e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HKECNGDP_00654	9.15e-41	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HKECNGDP_00655	2.41e-45	-	-	-	-	-	-	-	-
HKECNGDP_00656	1.18e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HKECNGDP_00658	8.45e-101	-	-	-	CP	-	-	-	Membrane
HKECNGDP_00661	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HKECNGDP_00662	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKECNGDP_00663	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKECNGDP_00664	1.23e-105	-	-	-	-	-	-	-	-
HKECNGDP_00665	3.32e-124	ywhD	-	-	S	-	-	-	YwhD family
HKECNGDP_00666	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
HKECNGDP_00667	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HKECNGDP_00668	3.42e-92	ywhA	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00669	5.69e-315	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HKECNGDP_00670	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HKECNGDP_00671	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HKECNGDP_00672	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HKECNGDP_00673	3.52e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HKECNGDP_00674	6.27e-67	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HKECNGDP_00675	3.23e-121	-	-	-	S	-	-	-	membrane
HKECNGDP_00676	2e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_00677	1.2e-214	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HKECNGDP_00680	2.45e-230	-	-	-	-	-	-	-	-
HKECNGDP_00682	9.14e-204	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HKECNGDP_00683	2.25e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_00684	2.51e-215	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKECNGDP_00685	5.83e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HKECNGDP_00686	1.98e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HKECNGDP_00687	2.94e-181	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HKECNGDP_00688	2.21e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKECNGDP_00689	1.16e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HKECNGDP_00690	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HKECNGDP_00691	3.28e-180	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_00692	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HKECNGDP_00693	5.69e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HKECNGDP_00694	1.36e-284	ywfA	-	-	EGP	-	-	-	-transporter
HKECNGDP_00695	5.46e-262	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HKECNGDP_00696	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKECNGDP_00697	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HKECNGDP_00698	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKECNGDP_00699	3.15e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKECNGDP_00700	6.37e-77	-	-	-	-	-	-	-	-
HKECNGDP_00701	3.29e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HKECNGDP_00702	3.34e-208	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKECNGDP_00703	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKECNGDP_00704	6.9e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKECNGDP_00705	4.34e-237	spsG	-	-	M	-	-	-	Spore Coat
HKECNGDP_00706	4.29e-173	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HKECNGDP_00707	1.95e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HKECNGDP_00708	4.04e-207	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HKECNGDP_00709	3.06e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HKECNGDP_00710	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HKECNGDP_00711	1.29e-183	spsA	-	-	M	-	-	-	Spore Coat
HKECNGDP_00712	1.49e-89	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HKECNGDP_00713	6.23e-76	ywdK	-	-	S	-	-	-	small membrane protein
HKECNGDP_00714	3.96e-293	ywdJ	-	-	F	-	-	-	Xanthine uracil
HKECNGDP_00715	1.57e-62	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HKECNGDP_00716	4.18e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKECNGDP_00717	2.42e-194	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HKECNGDP_00719	4.92e-116	ywdD	-	-	-	-	-	-	-
HKECNGDP_00720	1.6e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HKECNGDP_00721	8.33e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKECNGDP_00722	3.52e-26	ywdA	-	-	-	-	-	-	-
HKECNGDP_00723	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKECNGDP_00724	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_00726	5.46e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HKECNGDP_00728	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKECNGDP_00729	3.3e-236	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_00730	1.9e-177	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HKECNGDP_00731	1.58e-263	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKECNGDP_00732	5.47e-103	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HKECNGDP_00733	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HKECNGDP_00734	1.6e-82	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HKECNGDP_00735	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HKECNGDP_00736	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKECNGDP_00737	2.21e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HKECNGDP_00738	5.74e-48	ydaS	-	-	S	-	-	-	membrane
HKECNGDP_00739	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKECNGDP_00740	1.04e-288	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKECNGDP_00741	2e-80	gtcA	-	-	S	-	-	-	GtrA-like protein
HKECNGDP_00742	1.25e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKECNGDP_00744	8.76e-167	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HKECNGDP_00745	3.45e-172	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
HKECNGDP_00746	3.61e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HKECNGDP_00747	7.01e-306	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HKECNGDP_00748	4.08e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKECNGDP_00749	4.54e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKECNGDP_00750	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00751	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HKECNGDP_00752	7.25e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HKECNGDP_00753	6.37e-124	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKECNGDP_00756	2.08e-136	-	-	-	-	-	-	-	-
HKECNGDP_00758	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HKECNGDP_00759	3.48e-103	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HKECNGDP_00760	1.69e-186	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HKECNGDP_00761	2.06e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HKECNGDP_00762	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HKECNGDP_00763	3.72e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HKECNGDP_00764	7.01e-228	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HKECNGDP_00765	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HKECNGDP_00767	2.57e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKECNGDP_00768	5.2e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKECNGDP_00769	1.22e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKECNGDP_00770	1.23e-181	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKECNGDP_00771	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HKECNGDP_00772	8.86e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKECNGDP_00773	5.44e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKECNGDP_00774	3.61e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKECNGDP_00775	1.39e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HKECNGDP_00776	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKECNGDP_00777	2.18e-215	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKECNGDP_00778	5.07e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKECNGDP_00779	1.79e-84	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HKECNGDP_00780	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKECNGDP_00781	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HKECNGDP_00782	6.12e-182	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HKECNGDP_00783	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HKECNGDP_00784	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKECNGDP_00785	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKECNGDP_00786	7.85e-205	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HKECNGDP_00787	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
HKECNGDP_00788	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HKECNGDP_00789	1.62e-186	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HKECNGDP_00790	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_00791	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_00792	9.2e-215	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HKECNGDP_00793	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HKECNGDP_00794	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKECNGDP_00795	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKECNGDP_00796	1.55e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKECNGDP_00797	1.17e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HKECNGDP_00798	6.63e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKECNGDP_00799	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKECNGDP_00800	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKECNGDP_00801	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKECNGDP_00802	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKECNGDP_00803	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HKECNGDP_00804	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKECNGDP_00805	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HKECNGDP_00806	4.08e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKECNGDP_00807	1.78e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKECNGDP_00808	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HKECNGDP_00809	2.29e-208	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKECNGDP_00810	1.38e-117	ylbP	-	-	K	-	-	-	n-acetyltransferase
HKECNGDP_00811	5.18e-110	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HKECNGDP_00812	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKECNGDP_00813	4.88e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HKECNGDP_00814	2.59e-295	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKECNGDP_00815	7.23e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKECNGDP_00816	1.23e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HKECNGDP_00817	1.68e-276	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HKECNGDP_00818	1.01e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKECNGDP_00819	4.27e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HKECNGDP_00821	3.94e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
HKECNGDP_00822	3.33e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HKECNGDP_00823	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HKECNGDP_00824	8.47e-87	ylbD	-	-	S	-	-	-	Putative coat protein
HKECNGDP_00825	2.8e-255	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HKECNGDP_00826	4.75e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HKECNGDP_00827	4.12e-79	ylbA	-	-	S	-	-	-	YugN-like family
HKECNGDP_00828	4.37e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HKECNGDP_00829	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HKECNGDP_00830	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HKECNGDP_00831	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKECNGDP_00832	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HKECNGDP_00833	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKECNGDP_00834	1.16e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HKECNGDP_00835	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKECNGDP_00836	8.22e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKECNGDP_00837	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HKECNGDP_00838	2.67e-223	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HKECNGDP_00839	3.53e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HKECNGDP_00840	9.42e-314	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HKECNGDP_00841	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKECNGDP_00842	1.61e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00843	2.44e-65	-	-	-	S	-	-	-	YlaH-like protein
HKECNGDP_00844	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKECNGDP_00845	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HKECNGDP_00846	2.64e-60	ylaE	-	-	-	-	-	-	-
HKECNGDP_00848	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HKECNGDP_00849	1.3e-108	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HKECNGDP_00850	8.12e-196	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HKECNGDP_00851	7.89e-32	ykzI	-	-	-	-	-	-	-
HKECNGDP_00852	8.15e-155	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HKECNGDP_00853	9.4e-57	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKECNGDP_00854	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HKECNGDP_00855	5.69e-192	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HKECNGDP_00856	7.97e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HKECNGDP_00857	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKECNGDP_00858	7.27e-302	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKECNGDP_00859	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKECNGDP_00860	7.79e-261	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKECNGDP_00861	3.48e-269	-	-	-	V	-	-	-	Beta-lactamase
HKECNGDP_00862	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HKECNGDP_00863	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_00864	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_00865	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_00866	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_00867	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
HKECNGDP_00868	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_00869	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HKECNGDP_00870	5.6e-134	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HKECNGDP_00871	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HKECNGDP_00872	2.29e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKECNGDP_00873	3.17e-189	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HKECNGDP_00874	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKECNGDP_00875	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKECNGDP_00876	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKECNGDP_00877	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HKECNGDP_00878	5.27e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HKECNGDP_00879	2.39e-312	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HKECNGDP_00880	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HKECNGDP_00881	3.72e-235	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HKECNGDP_00882	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HKECNGDP_00883	4.88e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKECNGDP_00884	1.21e-211	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKECNGDP_00885	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKECNGDP_00886	1.06e-49	ykoA	-	-	-	-	-	-	-
HKECNGDP_00887	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKECNGDP_00888	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HKECNGDP_00889	4.75e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HKECNGDP_00890	2.77e-171	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_00891	8.92e-271	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HKECNGDP_00892	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_00893	2e-246	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKECNGDP_00894	4.64e-140	yknW	-	-	S	-	-	-	Yip1 domain
HKECNGDP_00895	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HKECNGDP_00896	2.92e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HKECNGDP_00897	3.21e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HKECNGDP_00898	1.13e-308	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HKECNGDP_00899	3.46e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKECNGDP_00900	1.65e-140	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKECNGDP_00901	2.53e-218	yknT	-	-	-	ko:K06437	-	ko00000	-
HKECNGDP_00902	7.46e-127	rok	-	-	K	-	-	-	Repressor of ComK
HKECNGDP_00903	2.24e-101	ykuV	-	-	CO	-	-	-	thiol-disulfide
HKECNGDP_00904	8.56e-179	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HKECNGDP_00905	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HKECNGDP_00906	1.38e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKECNGDP_00907	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKECNGDP_00908	5.1e-102	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKECNGDP_00909	2.98e-214	ykuO	-	-	-	-	-	-	-
HKECNGDP_00910	3.15e-117	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKECNGDP_00911	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00912	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
HKECNGDP_00913	4.54e-37	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HKECNGDP_00914	1.25e-119	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HKECNGDP_00915	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00916	1.56e-296	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HKECNGDP_00918	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_00919	1.89e-199	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HKECNGDP_00920	5.14e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00921	6.53e-308	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_00922	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
HKECNGDP_00923	4.75e-214	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HKECNGDP_00924	6.38e-15	-	-	-	-	-	-	-	-
HKECNGDP_00925	1.62e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKECNGDP_00926	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00927	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKECNGDP_00928	9.9e-154	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HKECNGDP_00929	8.11e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HKECNGDP_00930	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HKECNGDP_00931	1.68e-254	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HKECNGDP_00932	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_00933	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKECNGDP_00934	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HKECNGDP_00935	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_00936	2.78e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HKECNGDP_00937	1.01e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_00939	9.11e-261	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HKECNGDP_00940	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HKECNGDP_00941	2.1e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
HKECNGDP_00942	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKECNGDP_00943	1.77e-143	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HKECNGDP_00944	4.16e-38	-	-	-	-	-	-	-	-
HKECNGDP_00945	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_00946	1.47e-59	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HKECNGDP_00948	1.44e-203	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HKECNGDP_00949	6.23e-47	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
HKECNGDP_00950	2.88e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKECNGDP_00951	1.72e-43	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKECNGDP_00952	3.13e-171	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKECNGDP_00953	1e-79	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKECNGDP_00955	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKECNGDP_00956	2.06e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKECNGDP_00957	6.25e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HKECNGDP_00958	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKECNGDP_00959	3.12e-252	-	-	-	-	-	-	-	-
HKECNGDP_00960	2.69e-232	ykvI	-	-	S	-	-	-	membrane
HKECNGDP_00961	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKECNGDP_00962	7.27e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HKECNGDP_00963	4.71e-168	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HKECNGDP_00964	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HKECNGDP_00965	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HKECNGDP_00967	2.6e-124	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HKECNGDP_00968	2.33e-149	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HKECNGDP_00969	1.4e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HKECNGDP_00970	2.73e-289	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HKECNGDP_00971	8.93e-292	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKECNGDP_00972	1.91e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKECNGDP_00973	8.17e-286	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HKECNGDP_00974	3.65e-250	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HKECNGDP_00976	4.58e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKECNGDP_00977	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_00978	1.85e-241	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HKECNGDP_00979	3.07e-32	ykzE	-	-	-	-	-	-	-
HKECNGDP_00980	2.46e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKECNGDP_00981	4.63e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HKECNGDP_00982	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKECNGDP_00983	1.97e-162	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HKECNGDP_00984	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HKECNGDP_00985	3.6e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HKECNGDP_00986	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_00987	3.54e-174	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HKECNGDP_00988	1.43e-131	ykoX	-	-	S	-	-	-	membrane-associated protein
HKECNGDP_00989	4.86e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HKECNGDP_00990	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HKECNGDP_00991	5.41e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HKECNGDP_00992	1.98e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HKECNGDP_00993	1.77e-35	ykoL	-	-	-	-	-	-	-
HKECNGDP_00994	1.11e-23	-	-	-	-	-	-	-	-
HKECNGDP_00995	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
HKECNGDP_00996	2.48e-309	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HKECNGDP_00998	3.79e-311	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HKECNGDP_00999	9.8e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKECNGDP_01000	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_01001	3.1e-169	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKECNGDP_01002	1.89e-191	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKECNGDP_01003	2.58e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKECNGDP_01004	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKECNGDP_01005	7.47e-154	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKECNGDP_01006	2.3e-276	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_01007	4.1e-181	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
HKECNGDP_01008	1.74e-275	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKECNGDP_01010	3.86e-81	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKECNGDP_01011	1.92e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HKECNGDP_01012	7.54e-115	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HKECNGDP_01013	6.87e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HKECNGDP_01014	1.37e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKECNGDP_01015	1.25e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKECNGDP_01016	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HKECNGDP_01017	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HKECNGDP_01018	2.02e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HKECNGDP_01019	5.44e-132	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKECNGDP_01020	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HKECNGDP_01021	3.59e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
HKECNGDP_01022	2.41e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HKECNGDP_01023	3.28e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01024	1.32e-218	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKECNGDP_01025	1.1e-257	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HKECNGDP_01026	2.29e-225	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HKECNGDP_01027	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKECNGDP_01028	2.64e-242	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01029	6.59e-227	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_01030	1.39e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_01031	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HKECNGDP_01033	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HKECNGDP_01034	1.52e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKECNGDP_01036	6.62e-231	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HKECNGDP_01037	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKECNGDP_01038	5.68e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HKECNGDP_01039	9.38e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKECNGDP_01040	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HKECNGDP_01041	1.43e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HKECNGDP_01042	6.58e-173	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HKECNGDP_01043	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HKECNGDP_01044	2.1e-216	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HKECNGDP_01045	1.35e-51	xhlB	-	-	S	-	-	-	SPP1 phage holin
HKECNGDP_01046	1.11e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HKECNGDP_01047	4.28e-176	xepA	-	-	-	-	-	-	-
HKECNGDP_01048	3.25e-40	xkdX	-	-	-	-	-	-	-
HKECNGDP_01050	6.2e-110	-	-	-	-	-	-	-	-
HKECNGDP_01051	3.63e-37	-	-	-	-	-	-	-	-
HKECNGDP_01052	7.1e-113	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HKECNGDP_01053	2.53e-211	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKECNGDP_01054	5.77e-76	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HKECNGDP_01055	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HKECNGDP_01056	1.54e-205	xkdQ	-	-	G	-	-	-	NLP P60 protein
HKECNGDP_01057	8.94e-143	xkdP	-	-	S	-	-	-	Lysin motif
HKECNGDP_01058	2.35e-274	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HKECNGDP_01059	4.33e-27	-	-	-	-	-	-	-	-
HKECNGDP_01060	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HKECNGDP_01061	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
HKECNGDP_01062	6.61e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HKECNGDP_01063	1.57e-20	-	-	-	-	-	-	-	-
HKECNGDP_01064	1.74e-73	xkdJ	-	-	-	-	-	-	-
HKECNGDP_01065	1.7e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HKECNGDP_01066	5.78e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HKECNGDP_01067	5.11e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HKECNGDP_01068	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
HKECNGDP_01069	8.8e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HKECNGDP_01070	7.64e-304	xkdE3	-	-	S	-	-	-	portal protein
HKECNGDP_01071	4.54e-261	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HKECNGDP_01072	4.8e-140	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HKECNGDP_01073	4.34e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HKECNGDP_01077	1.25e-195	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HKECNGDP_01079	3.78e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKECNGDP_01080	1.87e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HKECNGDP_01081	3.08e-141	yjqB	-	-	S	-	-	-	phage-related replication protein
HKECNGDP_01082	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
HKECNGDP_01083	2.37e-221	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HKECNGDP_01085	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HKECNGDP_01086	1.69e-102	yjoA	-	-	S	-	-	-	DinB family
HKECNGDP_01087	1.86e-166	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKECNGDP_01088	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HKECNGDP_01089	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HKECNGDP_01090	1.24e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HKECNGDP_01091	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HKECNGDP_01092	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HKECNGDP_01093	7.49e-281	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKECNGDP_01094	4.87e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HKECNGDP_01095	2.55e-120	yjlB	-	-	S	-	-	-	Cupin domain
HKECNGDP_01096	8.66e-229	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HKECNGDP_01097	1.53e-166	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01098	9.33e-155	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HKECNGDP_01099	1.6e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HKECNGDP_01100	1.73e-40	-	-	-	-	-	-	-	-
HKECNGDP_01101	4.38e-286	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKECNGDP_01102	1.8e-290	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HKECNGDP_01103	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HKECNGDP_01104	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HKECNGDP_01105	2.88e-131	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HKECNGDP_01106	7.32e-91	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HKECNGDP_01107	9.12e-30	yjfB	-	-	S	-	-	-	Putative motility protein
HKECNGDP_01109	2.48e-136	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HKECNGDP_01112	1.33e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKECNGDP_01113	5.89e-179	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HKECNGDP_01114	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKECNGDP_01115	3.63e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_01116	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKECNGDP_01117	6.62e-278	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKECNGDP_01118	3.61e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKECNGDP_01119	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKECNGDP_01120	1.34e-281	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HKECNGDP_01121	1.06e-106	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_01122	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HKECNGDP_01123	2.2e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKECNGDP_01124	1.72e-212	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HKECNGDP_01125	1.71e-14	yqaS	-	-	L	-	-	-	DNA packaging
HKECNGDP_01127	1.1e-51	-	-	-	S	-	-	-	YjcQ protein
HKECNGDP_01131	1.12e-16	-	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01133	6.79e-317	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HKECNGDP_01134	1.42e-29	-	-	-	-	-	-	-	-
HKECNGDP_01135	1.64e-101	-	-	-	-	-	-	-	-
HKECNGDP_01136	1.14e-41	-	-	-	-	-	-	-	-
HKECNGDP_01144	1.42e-15	-	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01148	7.5e-11	-	-	-	-	-	-	-	-
HKECNGDP_01149	1.95e-209	-	-	-	S	-	-	-	Pfam Transposase IS66
HKECNGDP_01150	7.64e-89	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKECNGDP_01152	1.34e-278	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKECNGDP_01153	2.77e-271	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKECNGDP_01154	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HKECNGDP_01155	5.73e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HKECNGDP_01156	3.66e-98	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKECNGDP_01157	1.76e-47	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HKECNGDP_01158	2.48e-171	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKECNGDP_01159	6.52e-160	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKECNGDP_01160	8.05e-179	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HKECNGDP_01161	1.23e-48	-	-	-	-	-	-	-	-
HKECNGDP_01162	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKECNGDP_01163	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HKECNGDP_01164	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HKECNGDP_01167	4.84e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HKECNGDP_01168	2.67e-68	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HKECNGDP_01169	8.38e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
HKECNGDP_01170	8.73e-99	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HKECNGDP_01171	1.61e-116	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HKECNGDP_01172	1.12e-103	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HKECNGDP_01173	1.65e-121	yjbX	-	-	S	-	-	-	Spore coat protein
HKECNGDP_01174	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HKECNGDP_01175	5.24e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKECNGDP_01176	3.57e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKECNGDP_01177	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKECNGDP_01178	5.3e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
HKECNGDP_01179	1.42e-271	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HKECNGDP_01180	1.34e-137	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HKECNGDP_01181	2.71e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKECNGDP_01182	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKECNGDP_01183	6.41e-185	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HKECNGDP_01184	2.01e-212	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKECNGDP_01185	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKECNGDP_01186	9.01e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HKECNGDP_01187	2.03e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HKECNGDP_01188	1.72e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_01189	2.28e-150	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKECNGDP_01190	1.22e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HKECNGDP_01191	2.46e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HKECNGDP_01192	3.14e-27	-	-	-	-	-	-	-	-
HKECNGDP_01193	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKECNGDP_01194	4.01e-282	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKECNGDP_01195	9.78e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKECNGDP_01196	2.77e-141	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HKECNGDP_01197	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKECNGDP_01198	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKECNGDP_01199	1.05e-296	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HKECNGDP_01200	3.64e-219	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01201	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01202	3.59e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_01203	2.53e-213	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_01204	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKECNGDP_01205	1.45e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HKECNGDP_01206	1.52e-188	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HKECNGDP_01207	3.87e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_01208	4.24e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_01209	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HKECNGDP_01210	2.52e-238	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01211	4.15e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_01212	2.14e-189	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HKECNGDP_01213	5.48e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKECNGDP_01214	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKECNGDP_01215	2.82e-44	yjzB	-	-	-	-	-	-	-
HKECNGDP_01216	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HKECNGDP_01217	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HKECNGDP_01218	1.43e-135	yjaV	-	-	-	-	-	-	-
HKECNGDP_01219	4.68e-180	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HKECNGDP_01220	5.24e-33	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKECNGDP_01221	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HKECNGDP_01222	2.48e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKECNGDP_01223	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HKECNGDP_01224	5.67e-258	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKECNGDP_01225	1.19e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HKECNGDP_01226	1.88e-177	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKECNGDP_01227	4.43e-291	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKECNGDP_01228	1.23e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKECNGDP_01229	9.72e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HKECNGDP_01230	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HKECNGDP_01231	3.35e-105	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HKECNGDP_01232	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HKECNGDP_01233	1.06e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKECNGDP_01234	1.52e-198	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKECNGDP_01235	1.49e-11	-	-	-	-	-	-	-	-
HKECNGDP_01236	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HKECNGDP_01237	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HKECNGDP_01238	1.61e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HKECNGDP_01239	1.3e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_01241	3.61e-307	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HKECNGDP_01242	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HKECNGDP_01243	6.25e-221	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
HKECNGDP_01244	1.85e-205	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HKECNGDP_01245	6.39e-79	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HKECNGDP_01246	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKECNGDP_01247	3.78e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_01248	6.14e-108	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HKECNGDP_01249	8.34e-240	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKECNGDP_01250	1.2e-95	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HKECNGDP_01251	3.11e-116	yisT	-	-	S	-	-	-	DinB family
HKECNGDP_01252	1.35e-205	yisR	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01253	3.72e-311	yisQ	-	-	V	-	-	-	Mate efflux family protein
HKECNGDP_01254	1.89e-171	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HKECNGDP_01255	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKECNGDP_01256	1.53e-123	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HKECNGDP_01257	2.22e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HKECNGDP_01258	8.91e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HKECNGDP_01259	2.25e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HKECNGDP_01260	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HKECNGDP_01261	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HKECNGDP_01262	8.51e-109	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HKECNGDP_01263	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HKECNGDP_01264	1.61e-84	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HKECNGDP_01265	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HKECNGDP_01266	2.18e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HKECNGDP_01267	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HKECNGDP_01268	5.72e-284	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKECNGDP_01269	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKECNGDP_01270	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HKECNGDP_01271	1.66e-156	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKECNGDP_01272	1.79e-122	yhjR	-	-	S	-	-	-	Rubrerythrin
HKECNGDP_01273	1.11e-141	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
HKECNGDP_01274	4.57e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_01275	2.42e-262	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HKECNGDP_01276	1.03e-123	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_01277	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HKECNGDP_01278	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKECNGDP_01279	9.47e-144	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HKECNGDP_01280	4.12e-79	yhjD	-	-	-	-	-	-	-
HKECNGDP_01281	1.37e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HKECNGDP_01282	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKECNGDP_01283	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HKECNGDP_01284	3.25e-55	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HKECNGDP_01285	3.36e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HKECNGDP_01286	1.91e-64	-	-	-	S	-	-	-	MepB protein
HKECNGDP_01287	3.21e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HKECNGDP_01288	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HKECNGDP_01289	1.09e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HKECNGDP_01290	9.48e-43	yhzC	-	-	S	-	-	-	IDEAL
HKECNGDP_01291	1.35e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_01292	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HKECNGDP_01293	1.13e-276	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HKECNGDP_01294	1.86e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKECNGDP_01295	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HKECNGDP_01296	1.82e-255	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HKECNGDP_01297	7.04e-133	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HKECNGDP_01298	4.62e-195	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HKECNGDP_01299	3.46e-265	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKECNGDP_01300	1.24e-298	yhfN	-	-	O	-	-	-	Peptidase M48
HKECNGDP_01301	2.38e-86	yhfM	-	-	-	-	-	-	-
HKECNGDP_01302	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HKECNGDP_01303	6.32e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
HKECNGDP_01304	5.31e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKECNGDP_01305	9.84e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HKECNGDP_01307	3.36e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKECNGDP_01308	7.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
HKECNGDP_01310	8.41e-235	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKECNGDP_01311	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HKECNGDP_01312	3.1e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_01313	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HKECNGDP_01314	2.13e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKECNGDP_01315	4.25e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HKECNGDP_01316	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKECNGDP_01317	1.21e-114	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HKECNGDP_01318	5.65e-311	yhfA	-	-	C	-	-	-	membrane
HKECNGDP_01319	5.11e-285	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKECNGDP_01320	3.02e-162	ecsC	-	-	S	-	-	-	EcsC protein family
HKECNGDP_01321	6.41e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKECNGDP_01322	1.82e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HKECNGDP_01323	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKECNGDP_01324	3.42e-258	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKECNGDP_01325	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HKECNGDP_01326	2.55e-24	-	-	-	-	-	-	-	-
HKECNGDP_01327	2.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HKECNGDP_01328	8.17e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HKECNGDP_01329	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HKECNGDP_01330	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HKECNGDP_01331	2.25e-182	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKECNGDP_01332	5.79e-43	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HKECNGDP_01333	2.04e-225	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HKECNGDP_01334	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKECNGDP_01335	5.26e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HKECNGDP_01336	2.05e-278	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HKECNGDP_01337	2.27e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_01338	5.99e-21	-	-	-	S	-	-	-	YhzD-like protein
HKECNGDP_01339	4.11e-175	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HKECNGDP_01341	1.87e-113	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HKECNGDP_01342	1.41e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HKECNGDP_01343	7.7e-316	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HKECNGDP_01344	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HKECNGDP_01345	1.03e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKECNGDP_01346	1.23e-258	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HKECNGDP_01347	8.1e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKECNGDP_01348	2.73e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HKECNGDP_01349	1.32e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HKECNGDP_01350	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HKECNGDP_01351	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HKECNGDP_01352	9.47e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HKECNGDP_01354	1.57e-141	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HKECNGDP_01355	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HKECNGDP_01356	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HKECNGDP_01358	2.49e-110	-	-	-	T	-	-	-	universal stress protein
HKECNGDP_01359	2.67e-124	ymcC	-	-	S	-	-	-	Membrane
HKECNGDP_01360	1.22e-114	pksA	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01361	8.4e-198	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HKECNGDP_01362	1.99e-200	nodB1	-	-	G	-	-	-	deacetylase
HKECNGDP_01363	3.42e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HKECNGDP_01364	1.11e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HKECNGDP_01365	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HKECNGDP_01366	1.28e-165	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKECNGDP_01367	4.77e-77	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKECNGDP_01368	2.48e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKECNGDP_01369	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HKECNGDP_01370	7.8e-301	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKECNGDP_01371	7e-287	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKECNGDP_01372	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HKECNGDP_01373	3.94e-307	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HKECNGDP_01374	1.59e-142	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKECNGDP_01375	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_01376	4.65e-255	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HKECNGDP_01377	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HKECNGDP_01378	5.08e-268	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKECNGDP_01379	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HKECNGDP_01380	7.83e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_01381	4.9e-263	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HKECNGDP_01382	7e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_01383	6.44e-177	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HKECNGDP_01384	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HKECNGDP_01385	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HKECNGDP_01386	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
HKECNGDP_01387	3.25e-97	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HKECNGDP_01388	5.74e-295	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HKECNGDP_01389	4.18e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HKECNGDP_01390	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
HKECNGDP_01391	2.4e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HKECNGDP_01392	3.68e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKECNGDP_01393	5.28e-263	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_01394	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HKECNGDP_01395	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HKECNGDP_01396	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKECNGDP_01397	8.1e-199	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKECNGDP_01398	1.04e-134	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HKECNGDP_01399	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKECNGDP_01408	9.03e-103	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HKECNGDP_01409	7.43e-170	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HKECNGDP_01410	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HKECNGDP_01411	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKECNGDP_01412	2.94e-198	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HKECNGDP_01413	2.16e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKECNGDP_01414	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKECNGDP_01415	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HKECNGDP_01416	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HKECNGDP_01417	3.69e-235	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HKECNGDP_01418	4.48e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HKECNGDP_01419	1.23e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKECNGDP_01420	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HKECNGDP_01421	1.99e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKECNGDP_01422	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKECNGDP_01423	3.62e-100	ytkA	-	-	S	-	-	-	YtkA-like
HKECNGDP_01425	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKECNGDP_01426	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HKECNGDP_01427	4.13e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKECNGDP_01428	2.16e-173	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKECNGDP_01429	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKECNGDP_01430	3.19e-239	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HKECNGDP_01431	1.57e-189	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HKECNGDP_01432	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HKECNGDP_01433	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HKECNGDP_01434	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKECNGDP_01435	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKECNGDP_01436	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HKECNGDP_01437	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKECNGDP_01438	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HKECNGDP_01439	2.02e-271	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HKECNGDP_01440	1.1e-186	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
HKECNGDP_01442	3.1e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HKECNGDP_01443	5.76e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HKECNGDP_01444	0.0	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_01445	2.84e-244	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKECNGDP_01446	7.09e-53	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HKECNGDP_01448	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HKECNGDP_01449	4.38e-209	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_01450	6.05e-225	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HKECNGDP_01451	1.06e-234	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HKECNGDP_01452	3.14e-210	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HKECNGDP_01453	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_01454	1.36e-287	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HKECNGDP_01455	1.5e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_01456	1.06e-222	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HKECNGDP_01457	2.3e-174	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_01458	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HKECNGDP_01459	7.66e-163	ywaF	-	-	S	-	-	-	Integral membrane protein
HKECNGDP_01460	3.5e-271	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HKECNGDP_01461	3.72e-178	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HKECNGDP_01462	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HKECNGDP_01463	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKECNGDP_01464	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HKECNGDP_01465	3.86e-68	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_01466	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HKECNGDP_01467	2.88e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HKECNGDP_01468	1.95e-218	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKECNGDP_01469	3.95e-311	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKECNGDP_01470	5.5e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_01471	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HKECNGDP_01472	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HKECNGDP_01473	3.73e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HKECNGDP_01474	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKECNGDP_01475	8.68e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKECNGDP_01476	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HKECNGDP_01477	2.58e-163	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKECNGDP_01478	6.38e-279	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HKECNGDP_01479	2.99e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKECNGDP_01480	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HKECNGDP_01481	2.38e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKECNGDP_01482	1.1e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HKECNGDP_01483	4.53e-211	ytlQ	-	-	-	-	-	-	-
HKECNGDP_01484	1.18e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKECNGDP_01485	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
HKECNGDP_01486	3.88e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
HKECNGDP_01487	3.72e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKECNGDP_01488	1.94e-211	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HKECNGDP_01489	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HKECNGDP_01490	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
HKECNGDP_01491	4.33e-260	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HKECNGDP_01492	5.77e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HKECNGDP_01493	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
HKECNGDP_01494	1.69e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HKECNGDP_01495	2.43e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKECNGDP_01496	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKECNGDP_01497	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKECNGDP_01498	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKECNGDP_01499	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HKECNGDP_01500	5.9e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HKECNGDP_01501	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HKECNGDP_01502	2.06e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKECNGDP_01503	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HKECNGDP_01504	1.22e-154	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HKECNGDP_01505	2.02e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HKECNGDP_01506	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKECNGDP_01507	1.71e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HKECNGDP_01508	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKECNGDP_01509	1.41e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKECNGDP_01510	3.06e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HKECNGDP_01511	9.98e-161	ygaZ	-	-	E	-	-	-	AzlC protein
HKECNGDP_01512	7.76e-191	-	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01513	1.74e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKECNGDP_01514	2.49e-178	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKECNGDP_01516	1.65e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HKECNGDP_01518	3.08e-274	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKECNGDP_01519	2.8e-68	-	-	-	UW	ko:K06236,ko:K07061	ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165	ko00000,ko00001,ko00536,ko02048,ko04516	Hep Hag repeat protein
HKECNGDP_01522	6.08e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HKECNGDP_01523	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKECNGDP_01524	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKECNGDP_01525	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HKECNGDP_01526	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKECNGDP_01527	2.41e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01528	1.77e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HKECNGDP_01529	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKECNGDP_01530	3.95e-308	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKECNGDP_01531	1.36e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HKECNGDP_01532	1.47e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKECNGDP_01533	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HKECNGDP_01534	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKECNGDP_01535	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HKECNGDP_01536	9.45e-196	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKECNGDP_01537	5.25e-234	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HKECNGDP_01538	2.77e-114	yteJ	-	-	S	-	-	-	RDD family
HKECNGDP_01539	1.81e-156	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HKECNGDP_01540	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HKECNGDP_01541	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKECNGDP_01542	1.84e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HKECNGDP_01543	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKECNGDP_01544	4.03e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HKECNGDP_01545	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKECNGDP_01546	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKECNGDP_01548	2.06e-184	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_01549	4.16e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HKECNGDP_01550	6.77e-305	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HKECNGDP_01551	3.57e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
HKECNGDP_01552	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HKECNGDP_01553	7.04e-32	-	-	-	-	-	-	-	-
HKECNGDP_01554	2.64e-114	ytrI	-	-	-	-	-	-	-
HKECNGDP_01555	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HKECNGDP_01556	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKECNGDP_01557	4.93e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HKECNGDP_01558	8.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKECNGDP_01559	1.9e-231	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKECNGDP_01560	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKECNGDP_01561	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKECNGDP_01562	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HKECNGDP_01563	4.05e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HKECNGDP_01564	1.14e-95	ytwI	-	-	S	-	-	-	membrane
HKECNGDP_01565	5.5e-83	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKECNGDP_01566	1.42e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HKECNGDP_01567	1.32e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HKECNGDP_01568	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HKECNGDP_01569	4.82e-166	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_01570	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HKECNGDP_01571	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKECNGDP_01572	3.63e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKECNGDP_01573	1.16e-137	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HKECNGDP_01574	5.08e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKECNGDP_01575	5.53e-206	ytbE	-	-	S	-	-	-	reductase
HKECNGDP_01576	5.63e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HKECNGDP_01577	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01578	2.19e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKECNGDP_01579	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HKECNGDP_01580	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKECNGDP_01581	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HKECNGDP_01582	3e-200	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKECNGDP_01583	5.42e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HKECNGDP_01584	1.63e-196	ytxC	-	-	S	-	-	-	YtxC-like family
HKECNGDP_01585	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKECNGDP_01586	1.7e-192	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKECNGDP_01587	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_01588	1.05e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HKECNGDP_01589	2.76e-69	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
HKECNGDP_01590	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKECNGDP_01591	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKECNGDP_01592	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKECNGDP_01593	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKECNGDP_01594	3.16e-55	ysdA	-	-	S	-	-	-	Membrane
HKECNGDP_01595	9.71e-90	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HKECNGDP_01596	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HKECNGDP_01597	1.71e-241	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HKECNGDP_01598	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HKECNGDP_01599	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HKECNGDP_01600	9.84e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKECNGDP_01601	5.07e-180	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HKECNGDP_01602	1.16e-285	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HKECNGDP_01603	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HKECNGDP_01604	4.38e-215	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HKECNGDP_01605	1.18e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HKECNGDP_01606	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HKECNGDP_01607	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HKECNGDP_01608	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HKECNGDP_01609	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
HKECNGDP_01610	1.25e-261	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HKECNGDP_01611	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HKECNGDP_01612	5.41e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKECNGDP_01613	2.56e-248	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKECNGDP_01614	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKECNGDP_01615	3.08e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKECNGDP_01616	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKECNGDP_01617	6.04e-109	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HKECNGDP_01618	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HKECNGDP_01619	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKECNGDP_01620	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HKECNGDP_01621	5.46e-158	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HKECNGDP_01622	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKECNGDP_01623	6.22e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_01624	1.23e-178	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HKECNGDP_01625	3.52e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HKECNGDP_01626	6.09e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HKECNGDP_01627	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HKECNGDP_01628	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKECNGDP_01629	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKECNGDP_01630	1.67e-272	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKECNGDP_01631	9.97e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKECNGDP_01632	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HKECNGDP_01633	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HKECNGDP_01634	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HKECNGDP_01635	3.79e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HKECNGDP_01636	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_01637	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_01638	4.68e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKECNGDP_01639	6.35e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HKECNGDP_01640	2.38e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKECNGDP_01641	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKECNGDP_01642	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKECNGDP_01646	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HKECNGDP_01647	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HKECNGDP_01648	5.6e-124	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	restriction modification system DNA specificity
HKECNGDP_01649	5.59e-17	res	-	-	L	-	-	-	Resolvase, N terminal domain
HKECNGDP_01652	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HKECNGDP_01653	7.17e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HKECNGDP_01654	6.75e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKECNGDP_01655	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKECNGDP_01656	1.01e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKECNGDP_01657	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKECNGDP_01658	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKECNGDP_01659	9.54e-241	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HKECNGDP_01660	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKECNGDP_01661	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKECNGDP_01662	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HKECNGDP_01663	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HKECNGDP_01664	3.1e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKECNGDP_01665	8.26e-116	ysxD	-	-	-	-	-	-	-
HKECNGDP_01666	1.76e-314	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKECNGDP_01667	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HKECNGDP_01668	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKECNGDP_01669	4.65e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HKECNGDP_01670	1.2e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HKECNGDP_01671	9.35e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HKECNGDP_01672	3.24e-292	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HKECNGDP_01673	2.21e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HKECNGDP_01674	1.53e-35	-	-	-	-	-	-	-	-
HKECNGDP_01675	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKECNGDP_01676	4.11e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKECNGDP_01677	1.27e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HKECNGDP_01678	5.38e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HKECNGDP_01679	8.25e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HKECNGDP_01680	2.5e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HKECNGDP_01681	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HKECNGDP_01682	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKECNGDP_01683	6.14e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HKECNGDP_01684	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKECNGDP_01685	3.94e-184	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HKECNGDP_01686	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HKECNGDP_01687	3.59e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HKECNGDP_01688	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKECNGDP_01689	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HKECNGDP_01690	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKECNGDP_01691	3.64e-140	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HKECNGDP_01692	7.1e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKECNGDP_01693	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HKECNGDP_01694	1.65e-205	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HKECNGDP_01695	3.02e-124	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HKECNGDP_01696	3.45e-286	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HKECNGDP_01697	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HKECNGDP_01698	3.69e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HKECNGDP_01699	2.99e-272	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKECNGDP_01700	1.9e-253	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HKECNGDP_01701	1.26e-60	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKECNGDP_01703	1.21e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HKECNGDP_01704	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKECNGDP_01705	6.17e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKECNGDP_01706	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HKECNGDP_01707	1.36e-244	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKECNGDP_01708	2.01e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKECNGDP_01709	8.51e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HKECNGDP_01710	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HKECNGDP_01711	2.03e-143	yrbG	-	-	S	-	-	-	membrane
HKECNGDP_01712	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKECNGDP_01713	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HKECNGDP_01714	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKECNGDP_01715	7.6e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HKECNGDP_01716	4.68e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKECNGDP_01717	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKECNGDP_01718	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKECNGDP_01719	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKECNGDP_01720	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKECNGDP_01721	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HKECNGDP_01724	7.06e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKECNGDP_01725	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKECNGDP_01726	2.39e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HKECNGDP_01727	9.19e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HKECNGDP_01728	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_01729	1.8e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HKECNGDP_01730	5.88e-281	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKECNGDP_01731	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HKECNGDP_01732	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKECNGDP_01733	1.76e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_01734	8.4e-42	yrzR	-	-	-	-	-	-	-
HKECNGDP_01735	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HKECNGDP_01736	1.54e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKECNGDP_01737	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKECNGDP_01738	3.14e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKECNGDP_01739	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HKECNGDP_01740	2.82e-238	yrrI	-	-	S	-	-	-	AI-2E family transporter
HKECNGDP_01741	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKECNGDP_01742	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKECNGDP_01743	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKECNGDP_01744	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKECNGDP_01745	2.31e-258	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKECNGDP_01746	4.68e-153	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HKECNGDP_01747	2.2e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HKECNGDP_01748	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HKECNGDP_01749	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKECNGDP_01750	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKECNGDP_01751	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HKECNGDP_01752	1.38e-121	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HKECNGDP_01753	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HKECNGDP_01754	4.18e-154	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HKECNGDP_01755	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKECNGDP_01756	2.28e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HKECNGDP_01757	4.58e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKECNGDP_01758	9.51e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
HKECNGDP_01759	3.22e-104	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HKECNGDP_01760	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HKECNGDP_01761	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HKECNGDP_01762	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HKECNGDP_01763	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HKECNGDP_01764	9.01e-121	yrhH	-	-	Q	-	-	-	methyltransferase
HKECNGDP_01765	9.62e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HKECNGDP_01766	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HKECNGDP_01767	3.09e-269	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_01768	4.57e-212	yybE	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_01769	1.96e-108	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKECNGDP_01770	3.42e-233	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
HKECNGDP_01771	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HKECNGDP_01772	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_01773	1.25e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKECNGDP_01774	6.21e-118	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKECNGDP_01775	1.49e-38	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKECNGDP_01776	9.72e-186	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKECNGDP_01777	1.69e-189	supH	-	-	S	-	-	-	hydrolase
HKECNGDP_01779	4.07e-122	-	-	-	S	-	-	-	DinB family
HKECNGDP_01780	2.48e-104	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HKECNGDP_01781	1.29e-201	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_01782	2.32e-62	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_01783	2.23e-127	yqaC	-	-	F	-	-	-	adenylate kinase activity
HKECNGDP_01784	9.97e-189	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HKECNGDP_01786	3.93e-13	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HKECNGDP_01787	2.09e-257	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HKECNGDP_01788	1.15e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKECNGDP_01789	4.36e-203	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HKECNGDP_01790	5.58e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_01791	3.01e-275	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HKECNGDP_01792	2.99e-35	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_01793	4.14e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HKECNGDP_01794	2.71e-179	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HKECNGDP_01795	3.07e-179	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKECNGDP_01797	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HKECNGDP_01798	1.13e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKECNGDP_01799	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKECNGDP_01800	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HKECNGDP_01801	4.11e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKECNGDP_01802	2.38e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HKECNGDP_01803	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKECNGDP_01804	8.39e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HKECNGDP_01805	9.79e-192	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKECNGDP_01806	1.98e-134	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HKECNGDP_01807	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKECNGDP_01808	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKECNGDP_01809	1.28e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKECNGDP_01810	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKECNGDP_01811	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HKECNGDP_01812	9.09e-280	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HKECNGDP_01813	3.5e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HKECNGDP_01814	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKECNGDP_01815	1.68e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HKECNGDP_01816	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKECNGDP_01817	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKECNGDP_01818	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKECNGDP_01819	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKECNGDP_01820	6.58e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HKECNGDP_01821	2.91e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKECNGDP_01822	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HKECNGDP_01823	1.37e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HKECNGDP_01824	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKECNGDP_01825	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HKECNGDP_01826	1.34e-295	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HKECNGDP_01827	3.16e-189	yqfA	-	-	S	-	-	-	UPF0365 protein
HKECNGDP_01828	1.26e-85	yqfB	-	-	-	-	-	-	-
HKECNGDP_01829	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HKECNGDP_01830	3.72e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HKECNGDP_01831	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HKECNGDP_01832	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HKECNGDP_01833	1.44e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKECNGDP_01834	5.28e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKECNGDP_01835	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKECNGDP_01836	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKECNGDP_01837	6e-24	-	-	-	S	-	-	-	YqzL-like protein
HKECNGDP_01838	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKECNGDP_01839	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKECNGDP_01840	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKECNGDP_01841	1.19e-144	ccpN	-	-	K	-	-	-	CBS domain
HKECNGDP_01842	5.46e-192	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKECNGDP_01843	2.25e-111	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HKECNGDP_01844	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKECNGDP_01845	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKECNGDP_01846	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HKECNGDP_01847	8.52e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKECNGDP_01848	5.35e-269	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKECNGDP_01849	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKECNGDP_01850	4.16e-89	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HKECNGDP_01851	1.05e-308	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKECNGDP_01852	6.01e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKECNGDP_01853	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HKECNGDP_01854	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HKECNGDP_01855	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HKECNGDP_01856	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HKECNGDP_01857	3.34e-80	yqfX	-	-	S	-	-	-	membrane
HKECNGDP_01858	1.97e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKECNGDP_01859	1.84e-64	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HKECNGDP_01860	2.54e-166	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HKECNGDP_01861	2.76e-99	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HKECNGDP_01862	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HKECNGDP_01863	6.78e-289	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HKECNGDP_01864	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HKECNGDP_01865	2.72e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKECNGDP_01866	6.1e-204	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKECNGDP_01867	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HKECNGDP_01868	5.02e-187	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKECNGDP_01869	2.32e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKECNGDP_01870	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKECNGDP_01871	3.42e-68	yqzD	-	-	-	-	-	-	-
HKECNGDP_01872	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKECNGDP_01873	8.62e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKECNGDP_01874	5.38e-11	yqgO	-	-	-	-	-	-	-
HKECNGDP_01875	1.21e-274	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HKECNGDP_01876	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKECNGDP_01877	1.45e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HKECNGDP_01878	3.12e-255	yqgU	-	-	-	-	-	-	-
HKECNGDP_01879	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
HKECNGDP_01880	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HKECNGDP_01881	5.96e-158	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HKECNGDP_01882	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HKECNGDP_01883	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HKECNGDP_01885	1.18e-189	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKECNGDP_01886	6.5e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HKECNGDP_01887	5.29e-238	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HKECNGDP_01888	3.84e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKECNGDP_01889	2.93e-236	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HKECNGDP_01890	4.46e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HKECNGDP_01891	2.37e-95	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
HKECNGDP_01892	1.27e-25	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HKECNGDP_01893	2.15e-86	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HKECNGDP_01894	5.73e-82	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HKECNGDP_01895	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
HKECNGDP_01896	1.39e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HKECNGDP_01897	1.98e-157	yqxM	-	-	-	ko:K19433	-	ko00000	-
HKECNGDP_01898	1.89e-102	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HKECNGDP_01899	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HKECNGDP_01900	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HKECNGDP_01901	2.31e-32	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HKECNGDP_01902	1.77e-194	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HKECNGDP_01903	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKECNGDP_01904	1.3e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HKECNGDP_01905	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKECNGDP_01906	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKECNGDP_01907	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HKECNGDP_01908	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HKECNGDP_01909	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HKECNGDP_01910	2.85e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HKECNGDP_01911	7.65e-83	yqhP	-	-	-	-	-	-	-
HKECNGDP_01912	1.04e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HKECNGDP_01913	3.99e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HKECNGDP_01914	5.18e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HKECNGDP_01915	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKECNGDP_01916	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HKECNGDP_01917	3.12e-221	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HKECNGDP_01918	1.7e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HKECNGDP_01919	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HKECNGDP_01920	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HKECNGDP_01921	7.43e-261	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HKECNGDP_01922	1.05e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HKECNGDP_01923	5.77e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HKECNGDP_01924	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HKECNGDP_01925	2.32e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKECNGDP_01926	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKECNGDP_01927	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_01928	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKECNGDP_01929	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKECNGDP_01930	5.6e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKECNGDP_01931	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKECNGDP_01932	9.49e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKECNGDP_01933	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKECNGDP_01934	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HKECNGDP_01935	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKECNGDP_01936	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKECNGDP_01937	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HKECNGDP_01938	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HKECNGDP_01939	3.03e-276	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKECNGDP_01942	9.67e-274	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HKECNGDP_01944	6.93e-147	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
HKECNGDP_01945	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HKECNGDP_01947	1.62e-135	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HKECNGDP_01948	1.56e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKECNGDP_01949	1.61e-271	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HKECNGDP_01950	1.45e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HKECNGDP_01951	6.16e-261	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HKECNGDP_01952	1.46e-262	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HKECNGDP_01953	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HKECNGDP_01954	4e-205	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HKECNGDP_01955	6.25e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HKECNGDP_01956	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HKECNGDP_01957	2.27e-193	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HKECNGDP_01958	1.58e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKECNGDP_01959	6.96e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HKECNGDP_01960	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKECNGDP_01961	7.89e-222	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKECNGDP_01962	1.7e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKECNGDP_01963	1.53e-285	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKECNGDP_01964	1.22e-218	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKECNGDP_01965	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HKECNGDP_01966	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HKECNGDP_01967	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKECNGDP_01968	1.51e-198	yloC	-	-	S	-	-	-	stress-induced protein
HKECNGDP_01969	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HKECNGDP_01970	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKECNGDP_01971	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKECNGDP_01972	6.24e-287	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKECNGDP_01973	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKECNGDP_01974	2.89e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKECNGDP_01975	1.36e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKECNGDP_01976	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKECNGDP_01977	1.52e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKECNGDP_01978	3.51e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKECNGDP_01979	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKECNGDP_01980	6.22e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKECNGDP_01981	5.06e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKECNGDP_01982	6.16e-152	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKECNGDP_01983	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKECNGDP_01984	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_01985	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HKECNGDP_01986	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HKECNGDP_01987	4.14e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HKECNGDP_01988	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKECNGDP_01989	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HKECNGDP_01990	3.14e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKECNGDP_01991	2.17e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HKECNGDP_01992	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKECNGDP_01993	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKECNGDP_01994	1.23e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKECNGDP_01995	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKECNGDP_01996	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKECNGDP_01997	1.57e-184	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HKECNGDP_01998	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKECNGDP_01999	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKECNGDP_02000	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKECNGDP_02001	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKECNGDP_02002	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
HKECNGDP_02003	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKECNGDP_02004	8.4e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKECNGDP_02005	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKECNGDP_02006	7.24e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKECNGDP_02007	8.29e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKECNGDP_02008	0.0	ylqG	-	-	-	-	-	-	-
HKECNGDP_02009	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HKECNGDP_02010	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKECNGDP_02011	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKECNGDP_02012	8.91e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HKECNGDP_02013	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKECNGDP_02014	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKECNGDP_02015	6.29e-220	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HKECNGDP_02016	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKECNGDP_02017	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKECNGDP_02018	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKECNGDP_02019	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HKECNGDP_02020	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HKECNGDP_02021	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HKECNGDP_02022	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HKECNGDP_02023	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKECNGDP_02024	1.08e-119	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HKECNGDP_02025	1.74e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HKECNGDP_02026	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HKECNGDP_02027	3.43e-89	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HKECNGDP_02028	3e-260	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HKECNGDP_02029	8.9e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HKECNGDP_02030	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HKECNGDP_02031	7.7e-80	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HKECNGDP_02032	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKECNGDP_02033	1.21e-247	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HKECNGDP_02034	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HKECNGDP_02035	2.57e-141	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HKECNGDP_02036	6.02e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HKECNGDP_02037	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HKECNGDP_02038	5.74e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HKECNGDP_02039	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKECNGDP_02040	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKECNGDP_02041	2.65e-248	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HKECNGDP_02042	9.02e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HKECNGDP_02043	4.97e-249	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HKECNGDP_02044	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HKECNGDP_02045	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HKECNGDP_02046	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HKECNGDP_02047	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HKECNGDP_02048	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_02049	1.44e-94	ylxL	-	-	-	-	-	-	-
HKECNGDP_02050	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKECNGDP_02051	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKECNGDP_02052	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKECNGDP_02053	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKECNGDP_02054	7.76e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKECNGDP_02055	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKECNGDP_02056	6.31e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKECNGDP_02057	1.15e-296	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKECNGDP_02058	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKECNGDP_02059	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKECNGDP_02060	1.14e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKECNGDP_02061	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKECNGDP_02062	5.57e-55	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HKECNGDP_02063	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HKECNGDP_02064	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKECNGDP_02065	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HKECNGDP_02066	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKECNGDP_02067	1e-218	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKECNGDP_02068	2.6e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKECNGDP_02069	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKECNGDP_02070	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKECNGDP_02071	1.02e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HKECNGDP_02072	2.06e-299	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HKECNGDP_02073	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HKECNGDP_02074	3.31e-206	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HKECNGDP_02075	4.75e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HKECNGDP_02076	1e-248	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKECNGDP_02077	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKECNGDP_02078	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKECNGDP_02079	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKECNGDP_02080	2.27e-166	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HKECNGDP_02081	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
HKECNGDP_02082	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKECNGDP_02083	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_02084	9.04e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_02085	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_02086	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HKECNGDP_02087	1.12e-306	albE	-	-	S	-	-	-	Peptidase M16
HKECNGDP_02088	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
HKECNGDP_02089	8.62e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HKECNGDP_02090	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HKECNGDP_02091	3.82e-184	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HKECNGDP_02092	5.76e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HKECNGDP_02093	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKECNGDP_02094	6.59e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKECNGDP_02095	8.4e-237	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKECNGDP_02096	7.76e-279	pbpX	-	-	V	-	-	-	Beta-lactamase
HKECNGDP_02097	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKECNGDP_02098	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HKECNGDP_02099	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HKECNGDP_02100	2.04e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HKECNGDP_02101	3.37e-272	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKECNGDP_02102	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKECNGDP_02103	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HKECNGDP_02104	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HKECNGDP_02105	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKECNGDP_02106	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKECNGDP_02107	1.18e-85	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKECNGDP_02108	3.97e-49	-	-	-	-	-	-	-	-
HKECNGDP_02110	1.72e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HKECNGDP_02111	1.65e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HKECNGDP_02112	4.5e-234	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HKECNGDP_02113	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HKECNGDP_02114	4.34e-48	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HKECNGDP_02115	4.24e-308	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HKECNGDP_02116	7.18e-186	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HKECNGDP_02117	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HKECNGDP_02118	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HKECNGDP_02119	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_02120	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_02121	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HKECNGDP_02122	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HKECNGDP_02123	1.38e-293	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HKECNGDP_02124	6.07e-102	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HKECNGDP_02125	1.28e-152	yoaK	-	-	S	-	-	-	Membrane
HKECNGDP_02126	2.78e-82	ymzB	-	-	-	-	-	-	-
HKECNGDP_02127	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HKECNGDP_02128	3.03e-06	-	-	-	-	-	-	-	-
HKECNGDP_02129	6.85e-164	ymaC	-	-	S	-	-	-	Replication protein
HKECNGDP_02130	1.71e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HKECNGDP_02131	7.46e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HKECNGDP_02132	8.25e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HKECNGDP_02134	5.96e-77	ymaF	-	-	S	-	-	-	YmaF family
HKECNGDP_02135	7.63e-221	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKECNGDP_02136	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HKECNGDP_02137	6e-59	-	-	-	-	-	-	-	-
HKECNGDP_02138	9.42e-29	ymzA	-	-	-	-	-	-	-
HKECNGDP_02139	1.61e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HKECNGDP_02140	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKECNGDP_02141	3.43e-236	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKECNGDP_02142	2.72e-142	ymaB	-	-	S	-	-	-	MutT family
HKECNGDP_02143	3.22e-150	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HKECNGDP_02144	8.99e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HKECNGDP_02145	3.14e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKECNGDP_02146	1.17e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HKECNGDP_02147	5.34e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HKECNGDP_02148	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKECNGDP_02149	1e-273	mrjp	-	-	G	-	-	-	Major royal jelly protein
HKECNGDP_02150	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HKECNGDP_02151	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKECNGDP_02152	2.22e-278	xylR	-	-	GK	-	-	-	ROK family
HKECNGDP_02153	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HKECNGDP_02154	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HKECNGDP_02155	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HKECNGDP_02158	2.21e-27	-	-	-	-	-	-	-	-
HKECNGDP_02159	1.77e-238	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKECNGDP_02160	4.09e-06	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HKECNGDP_02161	2.5e-184	yoaP	-	-	K	-	-	-	YoaP-like
HKECNGDP_02162	6.88e-130	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_02163	3.77e-29	-	-	-	-	-	-	-	-
HKECNGDP_02165	1.21e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HKECNGDP_02166	4.15e-258	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_02167	1.65e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
HKECNGDP_02168	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HKECNGDP_02169	1.5e-82	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKECNGDP_02170	4.49e-125	yvgO	-	-	-	-	-	-	-
HKECNGDP_02172	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HKECNGDP_02173	1.49e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HKECNGDP_02174	4.1e-184	yndL	-	-	S	-	-	-	Replication protein
HKECNGDP_02175	1.74e-11	-	-	-	-	-	-	-	-
HKECNGDP_02176	6.29e-185	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HKECNGDP_02177	3.2e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HKECNGDP_02179	3.18e-141	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKECNGDP_02180	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HKECNGDP_02181	5.22e-145	yneB	-	-	L	-	-	-	resolvase
HKECNGDP_02182	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HKECNGDP_02183	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKECNGDP_02184	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HKECNGDP_02185	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HKECNGDP_02186	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HKECNGDP_02187	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HKECNGDP_02188	7.09e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HKECNGDP_02189	2.27e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HKECNGDP_02190	1.18e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HKECNGDP_02191	2.09e-83	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HKECNGDP_02192	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HKECNGDP_02193	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HKECNGDP_02194	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKECNGDP_02195	2.01e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKECNGDP_02197	1e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HKECNGDP_02198	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HKECNGDP_02199	4.68e-71	yneQ	-	-	-	-	-	-	-
HKECNGDP_02200	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HKECNGDP_02201	9.09e-121	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKECNGDP_02202	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HKECNGDP_02203	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKECNGDP_02204	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKECNGDP_02205	2.21e-19	-	-	-	-	-	-	-	-
HKECNGDP_02206	1.82e-63	ynfC	-	-	-	-	-	-	-
HKECNGDP_02207	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HKECNGDP_02208	6.37e-231	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HKECNGDP_02209	3.09e-244	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HKECNGDP_02210	1.51e-146	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HKECNGDP_02211	2.2e-268	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HKECNGDP_02212	3.03e-193	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_02213	1.29e-233	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HKECNGDP_02214	1.59e-286	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
HKECNGDP_02215	8.47e-201	yndG	-	-	S	-	-	-	DoxX-like family
HKECNGDP_02216	3.17e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HKECNGDP_02217	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HKECNGDP_02218	9.74e-95	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
HKECNGDP_02219	9.99e-83	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKECNGDP_02221	8.09e-277	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
HKECNGDP_02222	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HKECNGDP_02223	1.48e-69	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
HKECNGDP_02224	9.79e-312	-	-	-	T	-	-	-	Histidine kinase
HKECNGDP_02225	1.54e-163	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKECNGDP_02226	0.0	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HKECNGDP_02227	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKECNGDP_02228	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02229	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02230	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02231	3.59e-283	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HKECNGDP_02233	1.37e-176	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKECNGDP_02234	4.5e-157	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKECNGDP_02235	4.31e-166	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKECNGDP_02236	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HKECNGDP_02237	1.12e-285	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HKECNGDP_02238	3.22e-246	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HKECNGDP_02239	4.49e-168	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HKECNGDP_02240	1.96e-273	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKECNGDP_02241	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HKECNGDP_02242	3.43e-188	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HKECNGDP_02243	2.26e-95	yngA	-	-	S	-	-	-	membrane
HKECNGDP_02244	4.35e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKECNGDP_02245	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HKECNGDP_02246	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKECNGDP_02247	6.08e-179	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HKECNGDP_02248	9.97e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HKECNGDP_02249	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HKECNGDP_02250	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HKECNGDP_02251	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKECNGDP_02252	1.08e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HKECNGDP_02253	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HKECNGDP_02254	1.67e-85	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HKECNGDP_02255	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
HKECNGDP_02256	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02257	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02258	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02259	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02260	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HKECNGDP_02261	7.85e-239	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKECNGDP_02262	3.69e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
HKECNGDP_02263	3.68e-125	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HKECNGDP_02265	3.26e-124	-	-	-	L	-	-	-	Integrase
HKECNGDP_02266	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HKECNGDP_02267	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HKECNGDP_02268	3.38e-256	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
HKECNGDP_02269	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HKECNGDP_02270	5.02e-18	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKECNGDP_02271	9.47e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_02272	3.43e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKECNGDP_02273	3.85e-08	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HKECNGDP_02274	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HKECNGDP_02275	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HKECNGDP_02276	1.76e-203	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_02277	1.63e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKECNGDP_02278	7.2e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKECNGDP_02279	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HKECNGDP_02280	2.45e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_02281	3.84e-53	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKECNGDP_02282	3.28e-180	yoxB	-	-	-	-	-	-	-
HKECNGDP_02283	1.1e-261	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HKECNGDP_02284	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HKECNGDP_02285	8.91e-248	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKECNGDP_02286	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKECNGDP_02288	4e-129	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_02289	1.45e-60	-	-	-	-	-	-	-	-
HKECNGDP_02290	7.79e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HKECNGDP_02291	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKECNGDP_02292	1.49e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HKECNGDP_02293	2.61e-173	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKECNGDP_02294	1.86e-122	yobS	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_02295	6.63e-173	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HKECNGDP_02296	3.18e-118	yobW	-	-	-	-	-	-	-
HKECNGDP_02297	7.69e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HKECNGDP_02298	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKECNGDP_02299	1.33e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HKECNGDP_02300	5.43e-183	-	-	-	J	-	-	-	Protein required for attachment to host cells
HKECNGDP_02301	1.6e-123	yocC	-	-	-	-	-	-	-
HKECNGDP_02302	4.53e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HKECNGDP_02304	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HKECNGDP_02305	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKECNGDP_02306	7.78e-143	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKECNGDP_02308	7.44e-78	yocK	-	-	T	-	-	-	general stress protein
HKECNGDP_02309	2.71e-13	yocL	-	-	-	-	-	-	-
HKECNGDP_02310	3.51e-13	yocN	-	-	-	-	-	-	-
HKECNGDP_02311	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKECNGDP_02312	9.63e-60	yozN	-	-	-	-	-	-	-
HKECNGDP_02313	6.36e-50	yocN	-	-	-	-	-	-	-
HKECNGDP_02314	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
HKECNGDP_02316	4.69e-43	yozC	-	-	-	-	-	-	-
HKECNGDP_02317	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKECNGDP_02318	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HKECNGDP_02319	4.76e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HKECNGDP_02320	1.45e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKECNGDP_02321	9.85e-215	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HKECNGDP_02322	1.15e-182	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKECNGDP_02323	2.47e-261	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HKECNGDP_02324	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HKECNGDP_02325	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HKECNGDP_02326	4.2e-209	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HKECNGDP_02327	9.26e-145	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKECNGDP_02328	2.12e-293	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HKECNGDP_02329	3.48e-287	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HKECNGDP_02330	1.64e-144	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKECNGDP_02332	4.85e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HKECNGDP_02333	8.69e-195	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKECNGDP_02334	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HKECNGDP_02335	4.69e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HKECNGDP_02336	1.05e-30	-	-	-	-	-	-	-	-
HKECNGDP_02337	2.96e-210	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HKECNGDP_02338	4.68e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HKECNGDP_02340	6.1e-88	iolK	-	-	S	-	-	-	tautomerase
HKECNGDP_02341	7.58e-90	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HKECNGDP_02342	1.2e-74	yodB	-	-	K	-	-	-	transcriptional
HKECNGDP_02343	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
HKECNGDP_02344	4.37e-143	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HKECNGDP_02345	1.55e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HKECNGDP_02346	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HKECNGDP_02347	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKECNGDP_02349	2.82e-60	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKECNGDP_02350	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKECNGDP_02351	4.31e-166	yodH	-	-	Q	-	-	-	Methyltransferase
HKECNGDP_02352	1.68e-50	yodI	-	-	-	-	-	-	-
HKECNGDP_02353	4.49e-192	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HKECNGDP_02354	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HKECNGDP_02356	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
HKECNGDP_02357	3.55e-132	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKECNGDP_02358	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
HKECNGDP_02360	1.9e-161	yodN	-	-	-	-	-	-	-
HKECNGDP_02361	2.02e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKECNGDP_02362	3.32e-61	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HKECNGDP_02363	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HKECNGDP_02364	1.64e-202	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HKECNGDP_02365	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HKECNGDP_02366	2.68e-159	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKECNGDP_02367	6.87e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKECNGDP_02368	1.19e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKECNGDP_02369	1.78e-26	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HKECNGDP_02371	8.11e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HKECNGDP_02372	4.28e-314	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HKECNGDP_02373	8.14e-63	cgeC	-	-	-	ko:K06321	-	ko00000	-
HKECNGDP_02374	1.35e-75	cgeA	-	-	-	ko:K06319	-	ko00000	-
HKECNGDP_02375	4.48e-231	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HKECNGDP_02376	2.61e-281	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HKECNGDP_02377	3.54e-95	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HKECNGDP_02382	3.48e-248	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HKECNGDP_02384	4.17e-22	-	-	-	S	-	-	-	amine dehydrogenase activity
HKECNGDP_02387	1.03e-79	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HKECNGDP_02388	2.71e-179	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKECNGDP_02389	1.33e-179	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HKECNGDP_02390	7.91e-216	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HKECNGDP_02391	1.71e-283	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HKECNGDP_02392	1.29e-88	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HKECNGDP_02393	3.28e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKECNGDP_02394	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKECNGDP_02395	5.18e-208	gspA	-	-	M	-	-	-	General stress
HKECNGDP_02396	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HKECNGDP_02397	1.53e-214	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HKECNGDP_02398	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKECNGDP_02399	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02400	2.56e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HKECNGDP_02401	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02402	1.31e-290	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKECNGDP_02403	3.86e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HKECNGDP_02404	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKECNGDP_02405	2.9e-68	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_02406	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKECNGDP_02407	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HKECNGDP_02408	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HKECNGDP_02409	5.36e-144	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKECNGDP_02410	1.15e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_02411	4.83e-231	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_02412	9.23e-214	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKECNGDP_02413	6.41e-77	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HKECNGDP_02414	4.43e-291	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKECNGDP_02415	1.18e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_02416	7.89e-66	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_02417	1.72e-303	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKECNGDP_02418	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKECNGDP_02419	4.4e-214	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HKECNGDP_02420	1.07e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKECNGDP_02421	4.37e-266	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HKECNGDP_02422	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HKECNGDP_02423	7.89e-246	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HKECNGDP_02424	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HKECNGDP_02425	1.52e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKECNGDP_02426	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HKECNGDP_02427	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HKECNGDP_02428	2.16e-239	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HKECNGDP_02429	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HKECNGDP_02430	6.74e-289	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HKECNGDP_02431	4.88e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HKECNGDP_02432	1.51e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_02433	4.41e-216	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKECNGDP_02434	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKECNGDP_02435	2.68e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HKECNGDP_02436	7.63e-249	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKECNGDP_02437	1.91e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKECNGDP_02440	1.54e-95	yxjI	-	-	S	-	-	-	LURP-one-related
HKECNGDP_02441	2.3e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HKECNGDP_02442	1.41e-210	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HKECNGDP_02443	2.34e-267	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKECNGDP_02444	5.32e-126	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HKECNGDP_02445	2.68e-67	yxiS	-	-	-	-	-	-	-
HKECNGDP_02446	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HKECNGDP_02447	2.72e-282	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HKECNGDP_02448	3.44e-186	bglS	-	-	M	-	-	-	licheninase activity
HKECNGDP_02449	3.99e-192	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HKECNGDP_02450	3.01e-281	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HKECNGDP_02451	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HKECNGDP_02452	3.08e-148	-	-	-	-	-	-	-	-
HKECNGDP_02453	1.65e-34	-	-	-	-	-	-	-	-
HKECNGDP_02454	6.68e-273	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
HKECNGDP_02455	3.62e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
HKECNGDP_02456	3.42e-153	-	-	-	-	-	-	-	-
HKECNGDP_02458	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HKECNGDP_02459	3.29e-258	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HKECNGDP_02460	8.08e-206	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HKECNGDP_02461	1.26e-96	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKECNGDP_02462	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKECNGDP_02463	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_02464	0.0	-	-	-	L	-	-	-	HKD family nuclease
HKECNGDP_02465	9.75e-85	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKECNGDP_02466	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HKECNGDP_02467	1.42e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HKECNGDP_02468	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HKECNGDP_02469	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKECNGDP_02470	1.57e-299	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HKECNGDP_02471	1.01e-226	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HKECNGDP_02472	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKECNGDP_02473	3.85e-297	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HKECNGDP_02474	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKECNGDP_02475	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKECNGDP_02476	1e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKECNGDP_02477	2.32e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HKECNGDP_02480	2.06e-42	yxeE	-	-	-	-	-	-	-
HKECNGDP_02481	2.06e-34	yxeD	-	-	-	-	-	-	-
HKECNGDP_02482	2.8e-46	-	-	-	-	-	-	-	-
HKECNGDP_02483	3.54e-229	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKECNGDP_02484	6.96e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKECNGDP_02485	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HKECNGDP_02486	3.28e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_02487	7.95e-224	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_02488	4.45e-157	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_02489	0.0	-	-	-	T	-	-	-	Histidine kinase
HKECNGDP_02490	1.57e-176	yvrH	-	-	T	-	-	-	Transcriptional regulator
HKECNGDP_02491	1.3e-211	-	-	-	V	ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_02492	1.36e-167	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	permease
HKECNGDP_02493	1.89e-170	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HKECNGDP_02495	1.31e-09	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKECNGDP_02496	1.33e-46	-	-	-	H	-	-	-	Flavoprotein
HKECNGDP_02497	1.7e-209	-	-	-	V	-	-	-	Domain of unknown function (DUF4135)
HKECNGDP_02498	1.32e-156	-	-	-	V	-	-	-	TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein
HKECNGDP_02499	9.88e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HKECNGDP_02500	1.03e-201	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HKECNGDP_02501	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HKECNGDP_02502	2.2e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKECNGDP_02503	4.48e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HKECNGDP_02504	3.39e-225	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKECNGDP_02505	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKECNGDP_02506	6.88e-232	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKECNGDP_02507	4.2e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKECNGDP_02508	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKECNGDP_02509	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HKECNGDP_02510	1.67e-222	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HKECNGDP_02511	1.1e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKECNGDP_02512	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HKECNGDP_02514	8.74e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKECNGDP_02515	1.07e-131	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKECNGDP_02516	1.18e-254	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_02517	9.05e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HKECNGDP_02518	7.69e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKECNGDP_02519	0.0	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKECNGDP_02520	1.37e-188	yxaL	-	-	S	-	-	-	PQQ-like domain
HKECNGDP_02521	2.57e-78	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HKECNGDP_02522	1.21e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKECNGDP_02523	1.62e-257	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKECNGDP_02524	9.49e-98	yxaI	-	-	S	-	-	-	membrane protein domain
HKECNGDP_02525	4e-164	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
HKECNGDP_02526	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HKECNGDP_02527	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HKECNGDP_02528	2.78e-292	-	-	-	S	-	-	-	Fic/DOC family
HKECNGDP_02529	5.26e-314	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HKECNGDP_02530	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HKECNGDP_02531	3.87e-111	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HKECNGDP_02532	5.47e-197	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HKECNGDP_02533	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HKECNGDP_02534	3.14e-111	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HKECNGDP_02535	5.3e-240	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HKECNGDP_02536	1.15e-234	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HKECNGDP_02537	0.0	-	-	-	T	-	-	-	Nacht domain
HKECNGDP_02538	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKECNGDP_02541	9.39e-277	yycP	-	-	-	-	-	-	-
HKECNGDP_02542	3.52e-171	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKECNGDP_02543	2.92e-231	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HKECNGDP_02544	6.61e-110	yycN	-	-	K	-	-	-	Acetyltransferase
HKECNGDP_02546	5.49e-261	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HKECNGDP_02547	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HKECNGDP_02548	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKECNGDP_02549	9.68e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HKECNGDP_02550	4.41e-86	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HKECNGDP_02551	1.89e-57	sdpR	-	-	K	-	-	-	transcriptional
HKECNGDP_02552	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HKECNGDP_02553	4.53e-189	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HKECNGDP_02554	0.0	-	-	-	S	-	-	-	ABC transporter
HKECNGDP_02555	6.06e-257	-	-	-	S	-	-	-	Major Facilitator Superfamily
HKECNGDP_02556	0.0	-	-	-	-	-	-	-	-
HKECNGDP_02557	1.1e-241	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HKECNGDP_02558	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HKECNGDP_02559	2.53e-13	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_02560	3.83e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKECNGDP_02561	9.84e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HKECNGDP_02562	9.79e-195	yycI	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_02563	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_02564	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_02565	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_02570	1.06e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKECNGDP_02571	1.63e-96	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKECNGDP_02572	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKECNGDP_02573	2.21e-38	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HKECNGDP_02575	3.6e-25	yycC	-	-	K	-	-	-	YycC-like protein
HKECNGDP_02576	2.97e-304	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HKECNGDP_02577	3.16e-259	-	-	-	S	-	-	-	Ecdysteroid kinase
HKECNGDP_02578	3.8e-296	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
HKECNGDP_02579	7.95e-307	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HKECNGDP_02580	7.21e-156	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HKECNGDP_02581	1.02e-158	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HKECNGDP_02582	6.45e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HKECNGDP_02583	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKECNGDP_02584	5.01e-204	yybS	-	-	S	-	-	-	membrane
HKECNGDP_02586	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HKECNGDP_02587	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_02588	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HKECNGDP_02589	3.54e-198	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKECNGDP_02590	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HKECNGDP_02591	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HKECNGDP_02592	2.4e-152	-	-	-	K	-	-	-	FCD domain
HKECNGDP_02593	7.85e-117	-	-	-	S	-	-	-	PFAM DinB family protein
HKECNGDP_02594	8.16e-205	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKECNGDP_02595	1.51e-204	-	-	-	K	-	-	-	LysR substrate binding domain
HKECNGDP_02596	1.13e-129	-	-	-	E	-	-	-	LysE type translocator
HKECNGDP_02597	5.56e-74	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKECNGDP_02598	9.83e-148	ydgI	-	-	C	-	-	-	nitroreductase
HKECNGDP_02599	3.36e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKECNGDP_02600	1.8e-192	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HKECNGDP_02601	1.85e-99	yybA	-	-	K	-	-	-	transcriptional
HKECNGDP_02602	6.32e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_02603	3.34e-211	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
HKECNGDP_02604	2.02e-88	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKECNGDP_02605	1.47e-212	-	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_02606	9.9e-74	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKECNGDP_02607	4.14e-61	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKECNGDP_02608	2.6e-313	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKECNGDP_02609	4.96e-164	-	-	-	EG	-	-	-	EamA-like transporter family
HKECNGDP_02610	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HKECNGDP_02611	2.54e-211	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKECNGDP_02612	2.16e-315	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HKECNGDP_02613	1.15e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKECNGDP_02614	1.84e-232	ccpB	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_02615	7.21e-188	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKECNGDP_02616	5e-130	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKECNGDP_02617	2.98e-135	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HKECNGDP_02618	4.51e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKECNGDP_02619	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKECNGDP_02620	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKECNGDP_02621	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKECNGDP_02622	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKECNGDP_02623	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_02624	1.67e-225	yyaD	-	-	S	-	-	-	Membrane
HKECNGDP_02625	5.74e-109	yhhY	-	-	K	-	-	-	FR47-like protein
HKECNGDP_02626	4.91e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HKECNGDP_02627	1.43e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKECNGDP_02628	1.18e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HKECNGDP_02629	6.61e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HKECNGDP_02630	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HKECNGDP_02631	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKECNGDP_02632	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKECNGDP_02633	6.6e-142	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HKECNGDP_02634	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKECNGDP_02635	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKECNGDP_02636	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKECNGDP_02637	3.45e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKECNGDP_02638	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HKECNGDP_02639	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKECNGDP_02640	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HKECNGDP_02641	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKECNGDP_02642	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKECNGDP_02643	2.89e-101	yclD	-	-	-	-	-	-	-
HKECNGDP_02644	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HKECNGDP_02645	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HKECNGDP_02646	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKECNGDP_02647	6.67e-203	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HKECNGDP_02648	9e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKECNGDP_02649	3.03e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HKECNGDP_02650	1.18e-170	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HKECNGDP_02651	7.33e-143	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HKECNGDP_02652	3.18e-168	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HKECNGDP_02653	1.19e-313	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HKECNGDP_02654	9.17e-216	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HKECNGDP_02655	3.86e-84	-	-	-	S	-	-	-	YcxB-like protein
HKECNGDP_02656	9.53e-317	-	-	-	E	-	-	-	Aminotransferase class I and II
HKECNGDP_02657	1.76e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HKECNGDP_02658	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HKECNGDP_02659	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02660	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKECNGDP_02661	4.1e-84	hxlR	-	-	K	-	-	-	transcriptional
HKECNGDP_02662	1.82e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HKECNGDP_02663	1.54e-124	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HKECNGDP_02664	1.09e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HKECNGDP_02665	3.78e-88	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HKECNGDP_02666	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKECNGDP_02667	3.31e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HKECNGDP_02668	2.67e-96	yckC	-	-	S	-	-	-	membrane
HKECNGDP_02669	7.02e-237	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKECNGDP_02670	7.88e-287	yciC	-	-	S	-	-	-	GTPases (G3E family)
HKECNGDP_02671	1.3e-281	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HKECNGDP_02672	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HKECNGDP_02673	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKECNGDP_02674	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HKECNGDP_02675	5.95e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HKECNGDP_02676	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HKECNGDP_02677	5.76e-243	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKECNGDP_02678	1.17e-289	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HKECNGDP_02679	1.81e-310	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKECNGDP_02680	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKECNGDP_02681	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HKECNGDP_02682	1.45e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HKECNGDP_02683	1.98e-234	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HKECNGDP_02684	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKECNGDP_02685	1.59e-302	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_02686	9.44e-189	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HKECNGDP_02687	3.2e-139	tmrB	-	-	S	-	-	-	AAA domain
HKECNGDP_02688	2.47e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HKECNGDP_02689	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKECNGDP_02690	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HKECNGDP_02691	3.84e-313	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HKECNGDP_02692	1.03e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HKECNGDP_02693	5.28e-146	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HKECNGDP_02694	6.92e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_02695	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HKECNGDP_02696	1.14e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKECNGDP_02697	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HKECNGDP_02698	1.48e-104	ycgB	-	-	-	-	-	-	-
HKECNGDP_02699	3.27e-293	ycgA	-	-	S	-	-	-	Membrane
HKECNGDP_02700	2.77e-271	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HKECNGDP_02701	7e-211	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKECNGDP_02702	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKECNGDP_02703	7.71e-294	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HKECNGDP_02704	1.5e-275	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HKECNGDP_02705	6.74e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
HKECNGDP_02706	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HKECNGDP_02707	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HKECNGDP_02708	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HKECNGDP_02709	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HKECNGDP_02710	2.35e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HKECNGDP_02711	9.86e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_02712	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKECNGDP_02713	5.69e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKECNGDP_02714	1.81e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKECNGDP_02715	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKECNGDP_02716	2.58e-180	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HKECNGDP_02717	9.98e-249	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HKECNGDP_02718	3.62e-121	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HKECNGDP_02719	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_02720	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_02721	1.38e-227	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HKECNGDP_02722	3.78e-219	yccK	-	-	C	-	-	-	Aldo keto reductase
HKECNGDP_02723	1.68e-252	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HKECNGDP_02724	5.23e-144	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKECNGDP_02725	1.38e-254	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKECNGDP_02726	2.19e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HKECNGDP_02727	5.62e-310	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HKECNGDP_02728	2.34e-264	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HKECNGDP_02729	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKECNGDP_02730	2.86e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKECNGDP_02731	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKECNGDP_02732	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HKECNGDP_02733	1.33e-104	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HKECNGDP_02734	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HKECNGDP_02735	1.32e-74	ydfQ	-	-	CO	-	-	-	Thioredoxin
HKECNGDP_02736	1.14e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HKECNGDP_02737	1.06e-235	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HKECNGDP_02738	9.49e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HKECNGDP_02739	2.59e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKECNGDP_02740	2.73e-30	-	-	-	L	-	-	-	Transposase
HKECNGDP_02741	3.06e-40	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HKECNGDP_02742	3.62e-45	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HKECNGDP_02743	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HKECNGDP_02744	7.61e-280	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_02745	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HKECNGDP_02746	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HKECNGDP_02747	4.14e-230	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HKECNGDP_02748	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKECNGDP_02749	4.13e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HKECNGDP_02750	8.22e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKECNGDP_02751	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HKECNGDP_02752	2.58e-56	ybfN	-	-	-	-	-	-	-
HKECNGDP_02753	7.49e-195	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HKECNGDP_02754	4.26e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HKECNGDP_02755	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKECNGDP_02756	2.78e-272	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKECNGDP_02757	6.37e-257	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HKECNGDP_02758	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKECNGDP_02759	2.44e-45	-	-	-	-	-	-	-	-
HKECNGDP_02760	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HKECNGDP_02762	5.78e-267	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HKECNGDP_02763	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HKECNGDP_02764	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HKECNGDP_02765	1.04e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HKECNGDP_02766	7.3e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HKECNGDP_02768	8.56e-61	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKECNGDP_02769	0.0	ybeC	-	-	E	-	-	-	amino acid
HKECNGDP_02770	7.84e-55	ybyB	-	-	-	-	-	-	-
HKECNGDP_02771	5.07e-144	yqeB	-	-	-	-	-	-	-
HKECNGDP_02772	2.48e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HKECNGDP_02773	1.55e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
HKECNGDP_02774	8.47e-51	-	-	-	Q	-	-	-	Dimerisation domain
HKECNGDP_02775	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
HKECNGDP_02776	2.57e-121	-	-	-	Q	-	-	-	Flavin containing amine oxidoreductase
HKECNGDP_02777	0.0	-	-	-	Q	-	-	-	Polyketide synthase modules and related proteins
HKECNGDP_02778	0.0	-	-	-	Q	-	-	-	Beta-ketoacyl synthase
HKECNGDP_02779	5.47e-150	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	PFAM Acyl transferase
HKECNGDP_02780	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
HKECNGDP_02781	0.0	-	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
HKECNGDP_02782	2.79e-73	-	-	-	Q	-	-	-	Thioesterase domain
HKECNGDP_02783	1.62e-19	-	-	-	-	-	-	-	-
HKECNGDP_02784	1.89e-154	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKECNGDP_02785	4.3e-184	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKECNGDP_02786	9.14e-172	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_02787	1.24e-104	-	-	-	KT	-	-	-	helix_turn_helix, Lux Regulon
HKECNGDP_02788	3.53e-132	-	-	-	T	-	-	-	Histidine kinase
HKECNGDP_02789	4.51e-117	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKECNGDP_02790	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HKECNGDP_02791	5.62e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_02792	5.71e-67	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HKECNGDP_02793	7.37e-136	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HKECNGDP_02794	8.49e-206	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HKECNGDP_02795	1.5e-165	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HKECNGDP_02796	5.33e-125	ybdN	-	-	-	-	-	-	-
HKECNGDP_02797	8.23e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
HKECNGDP_02798	5.03e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKECNGDP_02799	3.76e-30	-	-	-	S	-	-	-	tetratricopeptide repeat
HKECNGDP_02800	6.54e-262	-	-	-	S	-	-	-	Peptidase C14 caspase catalytic subunit p20
HKECNGDP_02801	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKECNGDP_02802	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKECNGDP_02803	5.88e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_02804	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKECNGDP_02805	1.11e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HKECNGDP_02806	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_02812	1.93e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HKECNGDP_02813	8.67e-111	ybbJ	-	-	J	-	-	-	acetyltransferase
HKECNGDP_02814	2.32e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKECNGDP_02815	3.54e-311	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_02816	5.62e-312	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HKECNGDP_02817	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HKECNGDP_02818	1.35e-301	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_02819	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HKECNGDP_02820	2.1e-220	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HKECNGDP_02821	1.27e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_02822	4.79e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_02823	5.51e-143	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HKECNGDP_02824	4.41e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
HKECNGDP_02825	9.14e-287	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HKECNGDP_02826	8.03e-256	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HKECNGDP_02827	2.31e-232	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
HKECNGDP_02828	5.18e-313	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKECNGDP_02829	1.57e-281	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HKECNGDP_02830	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_02831	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_02832	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_02833	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKECNGDP_02834	4.87e-282	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HKECNGDP_02835	9.58e-307	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HKECNGDP_02836	2.68e-172	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HKECNGDP_02837	2.37e-186	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKECNGDP_02838	6.83e-224	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HKECNGDP_02839	4.13e-181	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKECNGDP_02840	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HKECNGDP_02841	6.33e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKECNGDP_02842	7.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKECNGDP_02844	2.15e-241	yueF	-	-	S	-	-	-	transporter activity
HKECNGDP_02846	1.07e-74	-	-	-	S	-	-	-	YolD-like protein
HKECNGDP_02847	5.69e-300	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKECNGDP_02848	1.15e-114	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HKECNGDP_02849	2.43e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HKECNGDP_02850	9.04e-230	yqkA	-	-	K	-	-	-	GrpB protein
HKECNGDP_02851	5.4e-80	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HKECNGDP_02852	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HKECNGDP_02853	1.05e-228	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKECNGDP_02854	7.85e-09	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HKECNGDP_02855	4.4e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HKECNGDP_02856	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HKECNGDP_02857	1.78e-98	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HKECNGDP_02858	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
HKECNGDP_02859	1.15e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_02860	1.3e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HKECNGDP_02861	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HKECNGDP_02862	2.06e-312	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HKECNGDP_02863	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HKECNGDP_02864	1.96e-30	-	-	-	-	-	-	-	-
HKECNGDP_02865	4.38e-47	yqkK	-	-	-	-	-	-	-
HKECNGDP_02867	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HKECNGDP_02868	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKECNGDP_02869	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HKECNGDP_02870	7.9e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKECNGDP_02871	4.97e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKECNGDP_02872	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKECNGDP_02873	6.08e-274	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKECNGDP_02874	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HKECNGDP_02875	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HKECNGDP_02876	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_02877	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HKECNGDP_02878	1.01e-78	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HKECNGDP_02879	9.92e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HKECNGDP_02880	3.89e-242	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HKECNGDP_02881	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HKECNGDP_02882	1.31e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HKECNGDP_02883	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HKECNGDP_02884	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKECNGDP_02885	5.64e-200	ypuA	-	-	S	-	-	-	Secreted protein
HKECNGDP_02886	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKECNGDP_02887	6.76e-106	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
HKECNGDP_02888	6.56e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKECNGDP_02889	4.92e-71	ypuD	-	-	-	-	-	-	-
HKECNGDP_02890	2.27e-269	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKECNGDP_02891	1.62e-143	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HKECNGDP_02892	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKECNGDP_02893	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKECNGDP_02894	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKECNGDP_02895	5.71e-121	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HKECNGDP_02897	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKECNGDP_02898	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKECNGDP_02899	1.51e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HKECNGDP_02900	5.41e-274	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKECNGDP_02901	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HKECNGDP_02902	3.66e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HKECNGDP_02903	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKECNGDP_02904	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HKECNGDP_02905	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HKECNGDP_02906	5.12e-251	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HKECNGDP_02907	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_02908	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKECNGDP_02909	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_02910	1.96e-254	rsiX	-	-	-	-	-	-	-
HKECNGDP_02911	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKECNGDP_02912	1.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKECNGDP_02913	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HKECNGDP_02914	8.64e-253	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HKECNGDP_02915	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKECNGDP_02916	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HKECNGDP_02917	6.15e-126	ypbE	-	-	M	-	-	-	Lysin motif
HKECNGDP_02918	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HKECNGDP_02919	4.68e-189	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HKECNGDP_02920	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKECNGDP_02921	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKECNGDP_02922	5.3e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HKECNGDP_02923	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HKECNGDP_02924	1.87e-213	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HKECNGDP_02925	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HKECNGDP_02926	7.01e-74	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HKECNGDP_02927	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HKECNGDP_02928	2.87e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKECNGDP_02929	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKECNGDP_02930	4.86e-237	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKECNGDP_02931	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
HKECNGDP_02932	2.52e-135	yphA	-	-	-	-	-	-	-
HKECNGDP_02933	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKECNGDP_02934	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKECNGDP_02935	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HKECNGDP_02936	6.87e-173	yphF	-	-	-	-	-	-	-
HKECNGDP_02937	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HKECNGDP_02938	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKECNGDP_02939	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HKECNGDP_02940	2.09e-45	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HKECNGDP_02941	3.96e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HKECNGDP_02942	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKECNGDP_02943	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKECNGDP_02944	8.53e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKECNGDP_02945	2e-181	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HKECNGDP_02946	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKECNGDP_02947	7.79e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKECNGDP_02948	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HKECNGDP_02949	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKECNGDP_02950	1.01e-212	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKECNGDP_02951	4.08e-168	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HKECNGDP_02952	1.29e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HKECNGDP_02953	1.73e-290	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKECNGDP_02954	1.89e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKECNGDP_02955	9.08e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKECNGDP_02956	1.02e-259	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HKECNGDP_02957	4.91e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKECNGDP_02958	8.74e-298	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HKECNGDP_02959	2.6e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HKECNGDP_02960	3.34e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HKECNGDP_02961	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HKECNGDP_02962	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HKECNGDP_02963	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HKECNGDP_02964	2.17e-135	ypjA	-	-	S	-	-	-	membrane
HKECNGDP_02965	3.39e-181	ypjB	-	-	S	-	-	-	sporulation protein
HKECNGDP_02966	1.16e-288	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HKECNGDP_02967	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HKECNGDP_02968	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HKECNGDP_02969	9.78e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKECNGDP_02970	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HKECNGDP_02971	5.24e-169	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HKECNGDP_02972	1.04e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HKECNGDP_02973	1.19e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKECNGDP_02974	6.35e-230	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKECNGDP_02975	3.27e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKECNGDP_02976	3.3e-201	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKECNGDP_02977	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKECNGDP_02978	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKECNGDP_02979	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HKECNGDP_02980	9.65e-105	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_02981	4.19e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKECNGDP_02982	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HKECNGDP_02983	1.39e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HKECNGDP_02984	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKECNGDP_02985	7.07e-117	ypoC	-	-	-	-	-	-	-
HKECNGDP_02986	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKECNGDP_02987	2.54e-145	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKECNGDP_02988	1.92e-237	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HKECNGDP_02989	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
HKECNGDP_02993	1.87e-75	yppG	-	-	S	-	-	-	YppG-like protein
HKECNGDP_02994	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKECNGDP_02995	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HKECNGDP_02996	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HKECNGDP_02997	6.67e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HKECNGDP_02999	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HKECNGDP_03000	1.33e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKECNGDP_03001	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKECNGDP_03002	5.46e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKECNGDP_03003	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
HKECNGDP_03005	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HKECNGDP_03006	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HKECNGDP_03007	9.52e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKECNGDP_03008	7.2e-298	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HKECNGDP_03009	2.52e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HKECNGDP_03010	1.54e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
HKECNGDP_03011	2.14e-43	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKECNGDP_03012	1.21e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HKECNGDP_03013	1.5e-64	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HKECNGDP_03014	8.15e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_03015	9.93e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HKECNGDP_03016	3.61e-117	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HKECNGDP_03017	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HKECNGDP_03018	8.23e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HKECNGDP_03019	2.44e-10	-	-	-	-	-	-	-	-
HKECNGDP_03020	3.33e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
HKECNGDP_03022	5.83e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HKECNGDP_03023	2.79e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HKECNGDP_03024	2.93e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HKECNGDP_03025	1.56e-38	ypeQ	-	-	S	-	-	-	Zinc-finger
HKECNGDP_03026	1.13e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HKECNGDP_03027	8.11e-17	degR	-	-	-	-	-	-	-
HKECNGDP_03028	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HKECNGDP_03029	1.56e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HKECNGDP_03030	2.3e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKECNGDP_03031	3.93e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HKECNGDP_03032	4.83e-130	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HKECNGDP_03033	5.71e-204	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HKECNGDP_03034	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HKECNGDP_03035	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HKECNGDP_03036	2.11e-173	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HKECNGDP_03037	1.86e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
HKECNGDP_03038	7.27e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKECNGDP_03039	3.01e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKECNGDP_03040	2.84e-149	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKECNGDP_03041	3.69e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HKECNGDP_03042	8.98e-228	yplP	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03043	1.73e-308	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKECNGDP_03044	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HKECNGDP_03045	2.53e-137	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HKECNGDP_03046	8.65e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKECNGDP_03047	7.94e-126	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03048	8.22e-90	ypoP	-	-	K	-	-	-	transcriptional
HKECNGDP_03049	1.2e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKECNGDP_03050	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKECNGDP_03051	3.43e-134	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HKECNGDP_03052	0.0	yokA	-	-	L	-	-	-	Recombinase
HKECNGDP_03056	1.42e-108	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HKECNGDP_03057	5.79e-107	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HKECNGDP_03060	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKECNGDP_03061	8.11e-237	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HKECNGDP_03062	2.06e-112	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HKECNGDP_03063	4.41e-214	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HKECNGDP_03064	0.0	ybeC	-	-	E	-	-	-	amino acid
HKECNGDP_03065	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03066	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HKECNGDP_03067	1.48e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HKECNGDP_03068	5.02e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HKECNGDP_03069	1.88e-153	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HKECNGDP_03070	4.15e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HKECNGDP_03071	1.58e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HKECNGDP_03072	2.49e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HKECNGDP_03074	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
HKECNGDP_03077	1.37e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKECNGDP_03078	2.79e-155	ydhC	-	-	K	-	-	-	FCD
HKECNGDP_03079	4e-210	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HKECNGDP_03080	2.32e-188	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HKECNGDP_03081	5.74e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKECNGDP_03082	2.98e-190	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKECNGDP_03083	3.56e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKECNGDP_03084	5.09e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HKECNGDP_03085	9e-158	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKECNGDP_03086	1.84e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKECNGDP_03087	6.78e-289	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKECNGDP_03088	2.35e-269	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HKECNGDP_03089	2.68e-248	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HKECNGDP_03090	6.07e-192	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HKECNGDP_03091	1.35e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_03092	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HKECNGDP_03093	1.58e-169	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HKECNGDP_03094	1.71e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
HKECNGDP_03095	8.22e-85	yraF	-	-	M	-	-	-	Spore coat protein
HKECNGDP_03096	3.04e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKECNGDP_03097	8.38e-34	yraE	-	-	-	ko:K06440	-	ko00000	-
HKECNGDP_03098	5.95e-65	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HKECNGDP_03099	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKECNGDP_03100	1.83e-202	ydeK	-	-	EG	-	-	-	-transporter
HKECNGDP_03101	3.45e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03102	1.52e-250	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HKECNGDP_03104	2.08e-146	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_03105	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKECNGDP_03106	6.92e-282	nhaC_1	-	-	C	-	-	-	antiporter
HKECNGDP_03107	7.29e-87	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HKECNGDP_03108	1.56e-258	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HKECNGDP_03109	8.41e-212	-	-	-	S	-	-	-	Sodium Bile acid symporter family
HKECNGDP_03110	1.69e-298	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HKECNGDP_03111	4.49e-192	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKECNGDP_03112	9.13e-191	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HKECNGDP_03113	1.08e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKECNGDP_03114	1.06e-109	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
HKECNGDP_03115	3.17e-75	ydeH	-	-	-	-	-	-	-
HKECNGDP_03116	2.49e-255	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HKECNGDP_03118	1.55e-188	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HKECNGDP_03120	1.82e-255	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HKECNGDP_03121	2.17e-215	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HKECNGDP_03122	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HKECNGDP_03125	1.01e-82	-	-	-	G	-	-	-	Cupin domain
HKECNGDP_03126	7.13e-110	-	-	-	S	-	-	-	DinB superfamily
HKECNGDP_03127	5.91e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
HKECNGDP_03128	3.34e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKECNGDP_03129	1.37e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HKECNGDP_03130	4.82e-155	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKECNGDP_03131	2.07e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HKECNGDP_03132	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HKECNGDP_03133	3.12e-250	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HKECNGDP_03134	3.89e-221	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKECNGDP_03135	1.92e-145	-	-	-	C	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HKECNGDP_03136	1.39e-114	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HKECNGDP_03138	9.05e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKECNGDP_03139	1.59e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03140	8.17e-83	-	-	-	S	-	-	-	YjbR
HKECNGDP_03141	8.35e-94	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HKECNGDP_03142	2.06e-44	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HKECNGDP_03143	9.33e-39	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HKECNGDP_03144	6.04e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03145	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HKECNGDP_03146	1.35e-124	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HKECNGDP_03147	3.94e-126	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKECNGDP_03148	1.76e-101	-	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03149	1.49e-38	-	-	-	S	-	-	-	Doxx family
HKECNGDP_03158	1.22e-75	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKECNGDP_03159	1.78e-21	-	-	-	-	-	-	-	-
HKECNGDP_03160	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HKECNGDP_03161	3.33e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HKECNGDP_03162	1.14e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKECNGDP_03163	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HKECNGDP_03164	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HKECNGDP_03165	8.83e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HKECNGDP_03166	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HKECNGDP_03167	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HKECNGDP_03168	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HKECNGDP_03169	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKECNGDP_03170	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HKECNGDP_03171	2.81e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKECNGDP_03172	1.57e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HKECNGDP_03173	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKECNGDP_03174	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HKECNGDP_03175	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HKECNGDP_03176	6.83e-109	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HKECNGDP_03177	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKECNGDP_03178	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKECNGDP_03179	1.25e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKECNGDP_03180	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
HKECNGDP_03181	5.73e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKECNGDP_03182	6.58e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
HKECNGDP_03183	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
HKECNGDP_03184	2.15e-261	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HKECNGDP_03185	2.29e-70	ydbL	-	-	-	-	-	-	-
HKECNGDP_03186	2.44e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKECNGDP_03187	1.08e-217	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_03188	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
HKECNGDP_03189	3.91e-287	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKECNGDP_03190	1.05e-152	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HKECNGDP_03191	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HKECNGDP_03192	5.43e-255	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HKECNGDP_03193	1.64e-199	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HKECNGDP_03194	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HKECNGDP_03195	1.53e-77	ydbB	-	-	G	-	-	-	Cupin domain
HKECNGDP_03196	6.55e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HKECNGDP_03197	5.39e-182	ydbA	-	-	P	-	-	-	EcsC protein family
HKECNGDP_03198	7.05e-72	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKECNGDP_03199	3.08e-93	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HKECNGDP_03200	1.95e-45	ydaT	-	-	-	-	-	-	-
HKECNGDP_03202	2.28e-289	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKECNGDP_03203	1.24e-52	-	-	-	-	-	-	-	-
HKECNGDP_03204	9.95e-129	-	-	-	-	-	-	-	-
HKECNGDP_03205	6.21e-115	-	-	-	-	-	-	-	-
HKECNGDP_03207	1.09e-11	-	-	-	-	-	-	-	-
HKECNGDP_03209	5.77e-268	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HKECNGDP_03210	3.67e-84	-	-	-	-	-	-	-	-
HKECNGDP_03211	4.55e-77	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKECNGDP_03212	2.74e-52	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HKECNGDP_03213	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKECNGDP_03214	5.33e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKECNGDP_03215	0.0	ydaO	-	-	E	-	-	-	amino acid
HKECNGDP_03216	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HKECNGDP_03217	4.54e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HKECNGDP_03218	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HKECNGDP_03219	9.32e-190	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HKECNGDP_03220	6.35e-255	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKECNGDP_03221	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKECNGDP_03222	7.97e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HKECNGDP_03223	6.54e-63	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HKECNGDP_03224	1.87e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKECNGDP_03225	1.5e-100	ydaG	-	-	S	-	-	-	general stress protein
HKECNGDP_03226	8.15e-149	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKECNGDP_03227	6.76e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HKECNGDP_03228	6.33e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_03229	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HKECNGDP_03230	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HKECNGDP_03231	7.36e-221	ycsN	-	-	S	-	-	-	Oxidoreductase
HKECNGDP_03232	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HKECNGDP_03233	2e-73	yczJ	-	-	S	-	-	-	biosynthesis
HKECNGDP_03235	1.91e-150	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HKECNGDP_03236	2.4e-169	kipR	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03237	8.48e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HKECNGDP_03238	3.28e-175	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HKECNGDP_03239	7.21e-194	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HKECNGDP_03240	3.24e-272	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HKECNGDP_03241	3.54e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HKECNGDP_03242	4.66e-178	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKECNGDP_03244	8.28e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HKECNGDP_03245	5.99e-266	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HKECNGDP_03246	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HKECNGDP_03247	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HKECNGDP_03248	9.6e-73	-	-	-	-	-	-	-	-
HKECNGDP_03249	1.43e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HKECNGDP_03250	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HKECNGDP_03251	1.69e-130	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03252	1.19e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_03253	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HKECNGDP_03254	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKECNGDP_03255	6.23e-287	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKECNGDP_03256	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKECNGDP_03257	1.94e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKECNGDP_03258	1.97e-59	ycnE	-	-	S	-	-	-	Monooxygenase
HKECNGDP_03259	6.86e-175	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HKECNGDP_03260	2.12e-195	ycnC	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03261	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HKECNGDP_03262	6.82e-224	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HKECNGDP_03263	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_03264	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_03265	7.78e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKECNGDP_03266	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKECNGDP_03268	1.2e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HKECNGDP_03269	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HKECNGDP_03270	9.08e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKECNGDP_03271	8.13e-306	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HKECNGDP_03272	6.34e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKECNGDP_03273	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HKECNGDP_03274	1.69e-277	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HKECNGDP_03275	5.6e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_03276	1.49e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HKECNGDP_03277	1.56e-183	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKECNGDP_03278	4.43e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKECNGDP_03279	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKECNGDP_03280	5.34e-248	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HKECNGDP_03281	3.43e-301	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HKECNGDP_03282	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HKECNGDP_03284	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HKECNGDP_03285	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HKECNGDP_03288	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKECNGDP_03289	7.6e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HKECNGDP_03290	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HKECNGDP_03291	5.97e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HKECNGDP_03292	1.16e-239	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HKECNGDP_03293	9.42e-83	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HKECNGDP_03294	1.53e-265	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HKECNGDP_03295	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKECNGDP_03296	2.94e-263	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HKECNGDP_03297	8.7e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HKECNGDP_03298	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKECNGDP_03299	9.89e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HKECNGDP_03300	5.65e-186	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKECNGDP_03301	5.01e-163	yfmS	-	-	NT	-	-	-	chemotaxis protein
HKECNGDP_03302	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKECNGDP_03303	2.93e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HKECNGDP_03304	2.7e-278	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_03305	2.95e-240	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HKECNGDP_03306	5.94e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HKECNGDP_03307	2.31e-230	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HKECNGDP_03308	1.95e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HKECNGDP_03309	1.02e-188	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HKECNGDP_03310	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HKECNGDP_03312	8.96e-186	-	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	methyltransferase
HKECNGDP_03313	1.96e-145	-	-	-	S	-	-	-	CAAX protease self-immunity
HKECNGDP_03314	6.41e-195	-	-	-	C	-	-	-	Nitroreductase family
HKECNGDP_03315	0.0	-	-	-	S	ko:K09136	-	ko00000,ko03009	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HKECNGDP_03316	6.23e-244	-	-	-	S	-	-	-	ATP diphosphatase activity
HKECNGDP_03317	1.98e-167	-	-	-	-	-	-	-	-
HKECNGDP_03318	2.75e-129	-	-	-	S	-	-	-	protein homooligomerization
HKECNGDP_03319	1.78e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKECNGDP_03320	2.17e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKECNGDP_03321	5.83e-67	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKECNGDP_03323	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HKECNGDP_03324	1.96e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HKECNGDP_03325	1.16e-262	yetM	-	-	CH	-	-	-	FAD binding domain
HKECNGDP_03326	2.08e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKECNGDP_03328	1.54e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKECNGDP_03329	7.43e-73	-	-	-	H	-	-	-	riboflavin kinase activity
HKECNGDP_03330	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HKECNGDP_03331	7.64e-198	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKECNGDP_03332	1.08e-84	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKECNGDP_03333	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HKECNGDP_03334	3.01e-155	yetF	-	-	S	-	-	-	membrane
HKECNGDP_03335	5.92e-05	-	-	-	-	-	-	-	-
HKECNGDP_03336	1.06e-127	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKECNGDP_03337	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HKECNGDP_03338	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HKECNGDP_03339	4.61e-61	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HKECNGDP_03340	4.94e-137	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HKECNGDP_03342	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HKECNGDP_03343	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HKECNGDP_03344	9.24e-74	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HKECNGDP_03345	1.4e-99	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HKECNGDP_03346	1.71e-54	-	-	-	S	-	-	-	Immunity protein 22
HKECNGDP_03347	0.0	-	-	-	K	-	-	-	SIR2-like domain
HKECNGDP_03348	2.5e-18	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HKECNGDP_03349	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKECNGDP_03350	4.95e-216	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKECNGDP_03351	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKECNGDP_03352	1.23e-194	yerO	-	-	K	-	-	-	Transcriptional regulator
HKECNGDP_03353	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKECNGDP_03354	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKECNGDP_03355	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKECNGDP_03356	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKECNGDP_03357	1.68e-157	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HKECNGDP_03358	3.11e-249	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HKECNGDP_03359	2.74e-286	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HKECNGDP_03360	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKECNGDP_03361	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKECNGDP_03362	3.55e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HKECNGDP_03363	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HKECNGDP_03364	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03365	1.73e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HKECNGDP_03366	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HKECNGDP_03367	1.7e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HKECNGDP_03368	8.44e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKECNGDP_03369	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKECNGDP_03370	4.22e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKECNGDP_03371	1.53e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKECNGDP_03372	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKECNGDP_03373	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKECNGDP_03374	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKECNGDP_03375	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKECNGDP_03376	8.68e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKECNGDP_03377	6.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKECNGDP_03378	7.55e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKECNGDP_03379	7.63e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKECNGDP_03380	6.56e-40	yebG	-	-	S	-	-	-	NETI protein
HKECNGDP_03381	4.41e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HKECNGDP_03383	4.36e-168	yebC	-	-	M	-	-	-	Membrane
HKECNGDP_03384	1.75e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKECNGDP_03385	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HKECNGDP_03386	2.81e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_03387	2.34e-165	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKECNGDP_03388	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKECNGDP_03389	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HKECNGDP_03390	9.37e-276	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HKECNGDP_03391	6.84e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HKECNGDP_03392	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKECNGDP_03393	4.33e-315	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HKECNGDP_03394	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HKECNGDP_03395	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HKECNGDP_03397	1.74e-195	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HKECNGDP_03398	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
HKECNGDP_03399	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HKECNGDP_03400	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKECNGDP_03401	1.04e-188	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HKECNGDP_03402	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HKECNGDP_03403	4.77e-209	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HKECNGDP_03404	1.11e-162	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HKECNGDP_03405	6.3e-229	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKECNGDP_03406	1.36e-146	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HKECNGDP_03407	1.47e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HKECNGDP_03408	4.74e-218	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKECNGDP_03409	9.08e-317	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HKECNGDP_03410	1.44e-256	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HKECNGDP_03411	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HKECNGDP_03412	0.0	res	3.1.21.5	-	V	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HKECNGDP_03413	1.94e-303	-	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HKECNGDP_03414	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKECNGDP_03415	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKECNGDP_03416	8.26e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKECNGDP_03417	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HKECNGDP_03418	1.65e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKECNGDP_03419	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKECNGDP_03420	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKECNGDP_03421	4.9e-116	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HKECNGDP_03422	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKECNGDP_03423	9.22e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKECNGDP_03424	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKECNGDP_03425	1.19e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HKECNGDP_03426	2.59e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HKECNGDP_03427	2.51e-236	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKECNGDP_03429	2.75e-213	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HKECNGDP_03430	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
HKECNGDP_03431	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKECNGDP_03432	8.04e-111	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HKECNGDP_03433	8.01e-313	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HKECNGDP_03434	9.08e-238	ygaE	-	-	S	-	-	-	Membrane
HKECNGDP_03435	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HKECNGDP_03436	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKECNGDP_03437	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HKECNGDP_03438	7.33e-07	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HKECNGDP_03439	3.81e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKECNGDP_03440	2.54e-50	yfhS	-	-	-	-	-	-	-
HKECNGDP_03441	3.2e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HKECNGDP_03442	2.94e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HKECNGDP_03443	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKECNGDP_03444	1.35e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HKECNGDP_03445	7.94e-218	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKECNGDP_03446	1.48e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HKECNGDP_03447	2.32e-121	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HKECNGDP_03448	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
HKECNGDP_03449	2.35e-214	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HKECNGDP_03451	8.19e-268	yfhI	-	-	EGP	-	-	-	-transporter
HKECNGDP_03452	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HKECNGDP_03453	1.28e-182	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HKECNGDP_03454	4.23e-215	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HKECNGDP_03456	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
HKECNGDP_03457	8.22e-138	yfhC	-	-	C	-	-	-	nitroreductase
HKECNGDP_03458	1.59e-212	yfhB	-	-	S	-	-	-	PhzF family
HKECNGDP_03459	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKECNGDP_03460	1.38e-108	yfiV	-	-	K	-	-	-	transcriptional
HKECNGDP_03461	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HKECNGDP_03462	2.8e-129	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HKECNGDP_03463	1.17e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HKECNGDP_03464	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HKECNGDP_03465	5.66e-238	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HKECNGDP_03466	1.72e-142	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKECNGDP_03467	5.62e-126	padR	-	-	K	-	-	-	transcriptional
HKECNGDP_03468	6.5e-218	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKECNGDP_03469	8.16e-206	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HKECNGDP_03470	1.93e-82	yfiD3	-	-	S	-	-	-	DoxX
HKECNGDP_03471	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HKECNGDP_03472	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKECNGDP_03473	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_03474	7.72e-179	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HKECNGDP_03475	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKECNGDP_03476	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HKECNGDP_03477	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HKECNGDP_03478	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKECNGDP_03479	3.96e-274	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKECNGDP_03480	3.59e-240	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKECNGDP_03481	3.21e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKECNGDP_03482	4.85e-114	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKECNGDP_03483	2.97e-245	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKECNGDP_03484	2.15e-67	-	-	-	S	-	-	-	YfzA-like protein
HKECNGDP_03485	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKECNGDP_03486	1.72e-208	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKECNGDP_03487	9.11e-236	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HKECNGDP_03489	5.62e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKECNGDP_03490	5.1e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HKECNGDP_03491	7.99e-37	yfjT	-	-	-	-	-	-	-
HKECNGDP_03492	1.97e-280	yfkA	-	-	S	-	-	-	YfkB-like domain
HKECNGDP_03493	2.58e-189	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HKECNGDP_03494	8.04e-186	yfkD	-	-	S	-	-	-	YfkD-like protein
HKECNGDP_03495	8.42e-239	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HKECNGDP_03496	1.02e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_03497	6.71e-12	-	-	-	-	-	-	-	-
HKECNGDP_03498	1.95e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKECNGDP_03499	1.76e-68	yfkI	-	-	S	-	-	-	gas vesicle protein
HKECNGDP_03500	6.88e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKECNGDP_03501	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HKECNGDP_03502	6.98e-252	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HKECNGDP_03503	2.04e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKECNGDP_03504	6.12e-210	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKECNGDP_03505	9.13e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKECNGDP_03506	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HKECNGDP_03507	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HKECNGDP_03508	3.13e-255	yibE	-	-	S	-	-	-	YibE/F-like protein
HKECNGDP_03509	6e-167	yibF	-	-	S	-	-	-	YibE/F-like protein
HKECNGDP_03510	1.45e-158	frp	-	-	C	-	-	-	nitroreductase
HKECNGDP_03511	1.18e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HKECNGDP_03512	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKECNGDP_03513	1.57e-313	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKECNGDP_03514	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HKECNGDP_03515	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HKECNGDP_03516	8.64e-106	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKECNGDP_03517	4.9e-83	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HKECNGDP_03518	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HKECNGDP_03519	4.75e-96	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HKECNGDP_03520	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HKECNGDP_03521	6.62e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HKECNGDP_03522	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HKECNGDP_03523	1.98e-26	yflI	-	-	-	-	-	-	-
HKECNGDP_03524	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HKECNGDP_03525	2.51e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03526	7.93e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKECNGDP_03527	8.63e-279	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HKECNGDP_03528	8.42e-193	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HKECNGDP_03529	2.01e-287	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HKECNGDP_03530	3.39e-227	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HKECNGDP_03531	4.62e-153	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKECNGDP_03532	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HKECNGDP_03533	1.12e-103	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKECNGDP_03534	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HKECNGDP_03535	7.13e-193	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKECNGDP_03536	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HKECNGDP_03541	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKECNGDP_03542	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HKECNGDP_03543	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HKECNGDP_03544	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HKECNGDP_03545	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKECNGDP_03546	3.12e-250	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HKECNGDP_03547	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HKECNGDP_03548	2.04e-159	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKECNGDP_03549	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKECNGDP_03550	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKECNGDP_03551	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HKECNGDP_03552	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKECNGDP_03553	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKECNGDP_03554	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKECNGDP_03555	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HKECNGDP_03556	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HKECNGDP_03557	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKECNGDP_03558	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKECNGDP_03559	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKECNGDP_03560	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKECNGDP_03561	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKECNGDP_03562	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKECNGDP_03563	4.37e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKECNGDP_03564	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKECNGDP_03565	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKECNGDP_03566	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HKECNGDP_03567	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKECNGDP_03568	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKECNGDP_03569	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKECNGDP_03570	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKECNGDP_03571	1.71e-241	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HKECNGDP_03572	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKECNGDP_03573	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKECNGDP_03574	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKECNGDP_03575	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKECNGDP_03576	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKECNGDP_03577	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKECNGDP_03578	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKECNGDP_03579	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKECNGDP_03580	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKECNGDP_03581	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKECNGDP_03582	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKECNGDP_03583	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKECNGDP_03584	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKECNGDP_03585	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKECNGDP_03586	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKECNGDP_03587	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKECNGDP_03588	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKECNGDP_03589	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKECNGDP_03590	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKECNGDP_03591	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKECNGDP_03592	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HKECNGDP_03593	7.75e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKECNGDP_03594	4.34e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKECNGDP_03595	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HKECNGDP_03596	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKECNGDP_03597	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKECNGDP_03598	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKECNGDP_03599	2.28e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKECNGDP_03600	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKECNGDP_03601	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKECNGDP_03602	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKECNGDP_03603	2.43e-190	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKECNGDP_03604	1.87e-176	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKECNGDP_03605	1.24e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKECNGDP_03606	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKECNGDP_03607	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKECNGDP_03608	1.45e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HKECNGDP_03609	4.47e-108	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
HKECNGDP_03610	1.08e-101	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HKECNGDP_03611	1.98e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HKECNGDP_03612	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKECNGDP_03613	6.81e-103	gerD	-	-	-	ko:K06294	-	ko00000	-
HKECNGDP_03614	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HKECNGDP_03615	6.38e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HKECNGDP_03616	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKECNGDP_03617	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKECNGDP_03618	6.1e-40	yazB	-	-	K	-	-	-	transcriptional
HKECNGDP_03619	2.75e-116	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKECNGDP_03620	1.13e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKECNGDP_03621	2.62e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKECNGDP_03622	1.4e-206	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HKECNGDP_03623	5.35e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HKECNGDP_03624	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKECNGDP_03625	1.47e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKECNGDP_03626	2.05e-200	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HKECNGDP_03627	3.19e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKECNGDP_03628	8.14e-178	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKECNGDP_03629	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKECNGDP_03630	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKECNGDP_03631	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKECNGDP_03632	5.47e-235	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKECNGDP_03633	3.79e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HKECNGDP_03634	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HKECNGDP_03637	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HKECNGDP_03638	1.2e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKECNGDP_03639	1.67e-134	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HKECNGDP_03640	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HKECNGDP_03641	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKECNGDP_03642	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HKECNGDP_03643	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKECNGDP_03644	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HKECNGDP_03645	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKECNGDP_03646	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HKECNGDP_03647	1.74e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKECNGDP_03648	6.18e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKECNGDP_03649	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKECNGDP_03650	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKECNGDP_03651	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HKECNGDP_03652	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HKECNGDP_03653	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKECNGDP_03654	1.11e-205	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKECNGDP_03655	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HKECNGDP_03656	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03657	1.41e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HKECNGDP_03658	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKECNGDP_03659	8.9e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKECNGDP_03660	1.01e-309	yabE	-	-	T	-	-	-	protein conserved in bacteria
HKECNGDP_03661	4.31e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HKECNGDP_03662	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKECNGDP_03663	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HKECNGDP_03664	2.85e-210	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKECNGDP_03665	4.03e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HKECNGDP_03666	8.05e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HKECNGDP_03667	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKECNGDP_03668	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HKECNGDP_03669	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKECNGDP_03670	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HKECNGDP_03671	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03672	7.75e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKECNGDP_03673	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HKECNGDP_03674	4.19e-245	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HKECNGDP_03675	2.93e-136	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKECNGDP_03676	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HKECNGDP_03677	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKECNGDP_03678	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HKECNGDP_03679	2.5e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HKECNGDP_03680	1.88e-92	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HKECNGDP_03681	4.58e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKECNGDP_03682	4.55e-137	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HKECNGDP_03683	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKECNGDP_03684	8.63e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
HKECNGDP_03685	3.33e-207	yhcP	-	-	-	-	-	-	-
HKECNGDP_03686	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKECNGDP_03687	9.56e-81	yhcM	-	-	-	-	-	-	-
HKECNGDP_03688	5.25e-293	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKECNGDP_03689	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HKECNGDP_03690	3.54e-191	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKECNGDP_03691	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKECNGDP_03692	3.85e-210	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKECNGDP_03693	4.75e-215	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_03694	1.2e-160	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKECNGDP_03695	4.71e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HKECNGDP_03696	2.33e-66	-	-	-	-	-	-	-	-
HKECNGDP_03697	1.41e-72	yhcC	-	-	-	-	-	-	-
HKECNGDP_03698	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKECNGDP_03699	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HKECNGDP_03700	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HKECNGDP_03701	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HKECNGDP_03702	1.77e-280	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HKECNGDP_03703	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HKECNGDP_03704	1.23e-07	-	-	-	-	-	-	-	-
HKECNGDP_03705	9.48e-93	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HKECNGDP_03706	8.03e-85	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HKECNGDP_03707	1.39e-140	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HKECNGDP_03708	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKECNGDP_03709	7.11e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
HKECNGDP_03710	2.83e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKECNGDP_03711	1.52e-144	yhzB	-	-	S	-	-	-	B3/4 domain
HKECNGDP_03713	6.39e-107	ygaO	-	-	-	-	-	-	-
HKECNGDP_03714	9.73e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKECNGDP_03715	3e-273	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HKECNGDP_03716	8.27e-186	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HKECNGDP_03717	1.06e-230	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HKECNGDP_03718	2.14e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HKECNGDP_03719	1.99e-235	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HKECNGDP_03720	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HKECNGDP_03721	6.64e-168	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_03722	1.64e-171	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKECNGDP_03723	7.21e-161	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKECNGDP_03724	5.52e-177	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKECNGDP_03725	1.48e-289	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HKECNGDP_03727	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
HKECNGDP_03728	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKECNGDP_03729	3.44e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HKECNGDP_03730	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
HKECNGDP_03737	2.78e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKECNGDP_03738	9.57e-315	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKECNGDP_03741	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HKECNGDP_03742	5.26e-123	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKECNGDP_03743	8.83e-209	-	-	-	K	-	-	-	LysR substrate binding domain
HKECNGDP_03744	4.53e-66	-	-	-	S	-	-	-	GlpM protein
HKECNGDP_03745	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HKECNGDP_03746	1.51e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKECNGDP_03747	2.77e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKECNGDP_03748	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKECNGDP_03749	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKECNGDP_03750	4.71e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKECNGDP_03751	1.3e-34	yqzJ	-	-	-	-	-	-	-
HKECNGDP_03752	2.05e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKECNGDP_03753	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HKECNGDP_03754	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKECNGDP_03755	4.64e-96	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HKECNGDP_03757	2.61e-123	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HKECNGDP_03758	1.6e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HKECNGDP_03759	2.12e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HKECNGDP_03760	1.04e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HKECNGDP_03761	3.37e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKECNGDP_03762	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_03763	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_03764	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HKECNGDP_03765	8.24e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
HKECNGDP_03766	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKECNGDP_03767	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKECNGDP_03768	7.47e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKECNGDP_03769	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKECNGDP_03770	1.59e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKECNGDP_03771	5.67e-259	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKECNGDP_03773	1.25e-157	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HKECNGDP_03774	4.04e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HKECNGDP_03775	1.75e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HKECNGDP_03776	3.53e-129	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HKECNGDP_03777	7.1e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKECNGDP_03778	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKECNGDP_03779	2.41e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKECNGDP_03780	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKECNGDP_03781	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKECNGDP_03782	6.44e-50	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HKECNGDP_03783	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HKECNGDP_03784	4.69e-172	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination