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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFEONIEA_00018	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HFEONIEA_00019	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HFEONIEA_00020	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFEONIEA_00021	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFEONIEA_00022	5.07e-261	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFEONIEA_00023	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HFEONIEA_00024	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HFEONIEA_00025	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFEONIEA_00026	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFEONIEA_00027	5.18e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFEONIEA_00028	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HFEONIEA_00029	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HFEONIEA_00030	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HFEONIEA_00031	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HFEONIEA_00032	3.97e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFEONIEA_00033	1.85e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HFEONIEA_00035	1.78e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFEONIEA_00036	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HFEONIEA_00037	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFEONIEA_00038	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFEONIEA_00039	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFEONIEA_00040	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HFEONIEA_00041	1.14e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFEONIEA_00042	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFEONIEA_00043	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HFEONIEA_00044	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFEONIEA_00045	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFEONIEA_00046	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFEONIEA_00047	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFEONIEA_00048	7.84e-207	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFEONIEA_00049	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFEONIEA_00050	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFEONIEA_00051	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFEONIEA_00052	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HFEONIEA_00053	1.19e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HFEONIEA_00054	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HFEONIEA_00055	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFEONIEA_00056	3.64e-101	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HFEONIEA_00057	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HFEONIEA_00058	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFEONIEA_00059	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HFEONIEA_00060	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFEONIEA_00061	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFEONIEA_00062	7.74e-47	-	-	-	-	-	-	-	-
HFEONIEA_00063	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFEONIEA_00064	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFEONIEA_00065	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HFEONIEA_00066	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFEONIEA_00067	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HFEONIEA_00068	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HFEONIEA_00069	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_00070	1e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFEONIEA_00071	0.0	-	-	-	N	-	-	-	domain, Protein
HFEONIEA_00072	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HFEONIEA_00073	1.02e-155	-	-	-	S	-	-	-	repeat protein
HFEONIEA_00074	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFEONIEA_00075	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFEONIEA_00076	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFEONIEA_00077	2.16e-39	-	-	-	-	-	-	-	-
HFEONIEA_00078	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFEONIEA_00079	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFEONIEA_00080	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFEONIEA_00081	1.07e-109	-	-	-	-	-	-	-	-
HFEONIEA_00082	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFEONIEA_00083	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HFEONIEA_00084	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HFEONIEA_00085	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFEONIEA_00086	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HFEONIEA_00087	6.16e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HFEONIEA_00088	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HFEONIEA_00089	1.67e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HFEONIEA_00090	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFEONIEA_00091	1.09e-309	-	-	-	-	-	-	-	-
HFEONIEA_00092	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFEONIEA_00093	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFEONIEA_00094	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HFEONIEA_00095	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HFEONIEA_00096	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFEONIEA_00097	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFEONIEA_00098	3.16e-156	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HFEONIEA_00099	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HFEONIEA_00100	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFEONIEA_00101	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFEONIEA_00102	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFEONIEA_00103	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFEONIEA_00104	5.01e-242	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_00105	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFEONIEA_00106	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFEONIEA_00107	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
HFEONIEA_00108	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFEONIEA_00109	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFEONIEA_00110	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFEONIEA_00111	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFEONIEA_00112	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HFEONIEA_00113	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFEONIEA_00114	5.12e-31	-	-	-	-	-	-	-	-
HFEONIEA_00115	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFEONIEA_00116	5.64e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00117	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFEONIEA_00118	8.82e-164	epsB	-	-	M	-	-	-	biosynthesis protein
HFEONIEA_00119	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HFEONIEA_00120	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HFEONIEA_00121	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HFEONIEA_00122	3.86e-163	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HFEONIEA_00123	6.24e-247	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HFEONIEA_00124	4.8e-229	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HFEONIEA_00125	2.9e-292	-	-	-	-	-	-	-	-
HFEONIEA_00126	1.61e-226	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HFEONIEA_00127	0.0	cps4J	-	-	S	-	-	-	MatE
HFEONIEA_00128	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HFEONIEA_00129	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HFEONIEA_00130	7.34e-219	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFEONIEA_00131	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HFEONIEA_00132	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFEONIEA_00133	6.62e-62	-	-	-	-	-	-	-	-
HFEONIEA_00134	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFEONIEA_00135	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_00136	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HFEONIEA_00137	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFEONIEA_00138	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFEONIEA_00139	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_00140	1.59e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFEONIEA_00141	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HFEONIEA_00142	9.79e-182	-	-	-	Q	-	-	-	Methyltransferase
HFEONIEA_00143	1.75e-43	-	-	-	-	-	-	-	-
HFEONIEA_00144	1.1e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFEONIEA_00154	6.22e-48	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HFEONIEA_00155	3.49e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFEONIEA_00157	1.38e-119	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HFEONIEA_00161	4.27e-34	-	-	-	-	-	-	-	-
HFEONIEA_00166	1.61e-21	-	-	-	-	-	-	-	-
HFEONIEA_00169	3.05e-169	-	-	-	S	-	-	-	Putative HNHc nuclease
HFEONIEA_00170	1.89e-94	-	-	-	L	-	-	-	DnaD domain protein
HFEONIEA_00171	1.02e-187	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HFEONIEA_00173	8.34e-62	-	-	-	-	-	-	-	-
HFEONIEA_00174	1.37e-05	-	-	-	-	-	-	-	-
HFEONIEA_00175	1.73e-52	-	-	-	S	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
HFEONIEA_00176	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HFEONIEA_00178	9.99e-97	-	-	-	K	-	-	-	acetyltransferase
HFEONIEA_00179	4.65e-40	-	-	-	S	-	-	-	ASCH
HFEONIEA_00180	5.58e-19	-	-	-	-	-	-	-	-
HFEONIEA_00183	9.53e-22	-	-	-	V	-	-	-	HNH endonuclease
HFEONIEA_00185	0.0	-	-	-	S	-	-	-	Phage Terminase
HFEONIEA_00186	2.95e-139	-	-	-	S	-	-	-	Portal protein
HFEONIEA_00187	6.32e-104	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HFEONIEA_00188	2.6e-127	-	-	-	S	-	-	-	Phage capsid family
HFEONIEA_00191	1.05e-33	-	-	-	S	-	-	-	Phage head-tail joining protein
HFEONIEA_00192	1.54e-49	-	-	-	-	-	-	-	-
HFEONIEA_00194	4.49e-92	-	-	-	S	-	-	-	Phage tail tube protein
HFEONIEA_00196	5.58e-06	-	-	-	-	-	-	-	-
HFEONIEA_00197	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HFEONIEA_00198	0.0	-	-	-	S	-	-	-	Phage tail protein
HFEONIEA_00199	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HFEONIEA_00203	3.42e-73	-	-	-	-	-	-	-	-
HFEONIEA_00205	2.18e-248	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HFEONIEA_00206	4.39e-62	-	-	-	-	-	-	-	-
HFEONIEA_00207	7.53e-55	-	-	-	S	-	-	-	Bacteriophage holin
HFEONIEA_00209	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HFEONIEA_00210	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFEONIEA_00211	8.63e-181	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFEONIEA_00212	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HFEONIEA_00213	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HFEONIEA_00214	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HFEONIEA_00215	3.81e-87	-	-	-	-	-	-	-	-
HFEONIEA_00216	1.01e-100	-	-	-	-	-	-	-	-
HFEONIEA_00217	3.01e-274	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HFEONIEA_00218	7.8e-123	-	-	-	-	-	-	-	-
HFEONIEA_00219	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFEONIEA_00220	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HFEONIEA_00221	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HFEONIEA_00222	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HFEONIEA_00223	3.4e-177	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFEONIEA_00224	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HFEONIEA_00225	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFEONIEA_00226	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HFEONIEA_00227	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFEONIEA_00228	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFEONIEA_00229	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFEONIEA_00230	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFEONIEA_00231	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFEONIEA_00232	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFEONIEA_00233	1.08e-289	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFEONIEA_00234	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFEONIEA_00235	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFEONIEA_00236	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFEONIEA_00237	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFEONIEA_00238	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HFEONIEA_00239	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HFEONIEA_00240	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFEONIEA_00241	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFEONIEA_00242	0.0	-	-	-	G	-	-	-	Major Facilitator
HFEONIEA_00243	9.01e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFEONIEA_00244	1.63e-121	-	-	-	-	-	-	-	-
HFEONIEA_00245	7.5e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFEONIEA_00246	2.44e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HFEONIEA_00247	9.8e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HFEONIEA_00248	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFEONIEA_00249	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFEONIEA_00250	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HFEONIEA_00251	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFEONIEA_00252	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFEONIEA_00253	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFEONIEA_00254	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFEONIEA_00255	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HFEONIEA_00256	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HFEONIEA_00257	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFEONIEA_00258	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HFEONIEA_00259	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFEONIEA_00260	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFEONIEA_00261	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFEONIEA_00262	1.73e-67	-	-	-	-	-	-	-	-
HFEONIEA_00263	4.78e-65	-	-	-	-	-	-	-	-
HFEONIEA_00264	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFEONIEA_00265	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HFEONIEA_00266	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFEONIEA_00267	2.56e-76	-	-	-	-	-	-	-	-
HFEONIEA_00268	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFEONIEA_00269	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFEONIEA_00270	1.35e-147	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HFEONIEA_00271	3.23e-214	-	-	-	G	-	-	-	Fructosamine kinase
HFEONIEA_00272	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HFEONIEA_00273	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFEONIEA_00274	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFEONIEA_00275	2.15e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFEONIEA_00276	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFEONIEA_00277	1.06e-283	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFEONIEA_00278	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFEONIEA_00279	4.26e-165	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFEONIEA_00280	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFEONIEA_00281	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFEONIEA_00282	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HFEONIEA_00283	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HFEONIEA_00284	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFEONIEA_00285	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HFEONIEA_00286	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFEONIEA_00287	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFEONIEA_00288	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFEONIEA_00289	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFEONIEA_00290	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFEONIEA_00291	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFEONIEA_00292	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HFEONIEA_00293	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00294	2.59e-256	-	-	-	-	-	-	-	-
HFEONIEA_00295	2.03e-251	-	-	-	-	-	-	-	-
HFEONIEA_00296	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFEONIEA_00297	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00298	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HFEONIEA_00299	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFEONIEA_00300	5.9e-103	-	-	-	K	-	-	-	MarR family
HFEONIEA_00301	2.71e-108	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFEONIEA_00303	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_00304	8.22e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HFEONIEA_00305	4.7e-262	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFEONIEA_00306	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HFEONIEA_00307	2.64e-83	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFEONIEA_00308	2.22e-224	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFEONIEA_00310	9.29e-222	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HFEONIEA_00311	6.89e-176	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00312	2.16e-17	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00313	8.62e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HFEONIEA_00314	4.15e-145	-	-	-	GM	-	-	-	NmrA-like family
HFEONIEA_00315	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HFEONIEA_00316	2.13e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFEONIEA_00317	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HFEONIEA_00318	3.72e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HFEONIEA_00319	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_00320	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_00321	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HFEONIEA_00322	7.57e-272	-	-	-	S	-	-	-	membrane
HFEONIEA_00323	6.13e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_00324	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HFEONIEA_00325	1.34e-144	-	-	-	GM	-	-	-	epimerase
HFEONIEA_00326	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HFEONIEA_00327	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HFEONIEA_00328	4.03e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HFEONIEA_00329	1.97e-175	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HFEONIEA_00330	1.35e-147	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFEONIEA_00331	1.01e-229	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFEONIEA_00332	6.03e-270	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFEONIEA_00333	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00334	1.08e-305	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HFEONIEA_00335	3.49e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFEONIEA_00336	5.15e-252	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HFEONIEA_00337	1.67e-233	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HFEONIEA_00338	1.24e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFEONIEA_00339	1.49e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HFEONIEA_00340	9.58e-267	-	-	-	-	-	-	-	-
HFEONIEA_00341	1.75e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_00342	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
HFEONIEA_00343	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFEONIEA_00344	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_00345	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_00346	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HFEONIEA_00347	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HFEONIEA_00348	1.96e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFEONIEA_00349	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFEONIEA_00350	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFEONIEA_00351	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFEONIEA_00353	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFEONIEA_00354	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFEONIEA_00355	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFEONIEA_00356	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFEONIEA_00357	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HFEONIEA_00358	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HFEONIEA_00359	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFEONIEA_00360	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFEONIEA_00361	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFEONIEA_00362	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFEONIEA_00363	4.46e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFEONIEA_00364	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFEONIEA_00365	5.15e-247	-	-	-	S	-	-	-	Helix-turn-helix domain
HFEONIEA_00366	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFEONIEA_00367	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HFEONIEA_00368	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFEONIEA_00369	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFEONIEA_00370	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFEONIEA_00371	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFEONIEA_00372	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HFEONIEA_00373	9.1e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFEONIEA_00374	1.14e-184	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFEONIEA_00375	8.58e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFEONIEA_00376	6.46e-109	-	-	-	-	-	-	-	-
HFEONIEA_00377	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00378	1.64e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFEONIEA_00379	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFEONIEA_00380	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HFEONIEA_00381	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFEONIEA_00382	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HFEONIEA_00383	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFEONIEA_00384	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HFEONIEA_00385	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_00386	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HFEONIEA_00387	1.5e-161	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HFEONIEA_00388	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFEONIEA_00389	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HFEONIEA_00391	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFEONIEA_00392	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFEONIEA_00393	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HFEONIEA_00394	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFEONIEA_00395	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFEONIEA_00396	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HFEONIEA_00397	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFEONIEA_00398	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFEONIEA_00399	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFEONIEA_00400	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFEONIEA_00401	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFEONIEA_00402	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFEONIEA_00403	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00404	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HFEONIEA_00405	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFEONIEA_00406	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFEONIEA_00407	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HFEONIEA_00408	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HFEONIEA_00409	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFEONIEA_00410	1.83e-314	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HFEONIEA_00411	1.86e-86	-	-	-	-	-	-	-	-
HFEONIEA_00412	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFEONIEA_00413	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_00414	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFEONIEA_00415	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFEONIEA_00416	8.63e-275	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFEONIEA_00417	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HFEONIEA_00418	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HFEONIEA_00419	8.23e-291	-	-	-	-	-	-	-	-
HFEONIEA_00420	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFEONIEA_00421	4.51e-77	-	-	-	-	-	-	-	-
HFEONIEA_00422	1.09e-178	-	-	-	-	-	-	-	-
HFEONIEA_00423	7.13e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFEONIEA_00424	2.13e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HFEONIEA_00425	2.98e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HFEONIEA_00426	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HFEONIEA_00428	7.81e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_00429	6.64e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HFEONIEA_00430	1.23e-63	-	-	-	-	-	-	-	-
HFEONIEA_00431	3.15e-29	-	-	-	-	-	-	-	-
HFEONIEA_00432	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HFEONIEA_00433	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HFEONIEA_00434	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HFEONIEA_00435	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00436	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HFEONIEA_00437	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFEONIEA_00438	5.3e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00439	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
HFEONIEA_00441	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HFEONIEA_00442	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HFEONIEA_00443	9.52e-25	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HFEONIEA_00444	7.13e-112	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HFEONIEA_00446	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HFEONIEA_00447	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HFEONIEA_00448	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFEONIEA_00449	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HFEONIEA_00450	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFEONIEA_00451	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFEONIEA_00452	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFEONIEA_00453	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HFEONIEA_00454	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HFEONIEA_00455	6.37e-85	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HFEONIEA_00456	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HFEONIEA_00457	1.99e-132	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HFEONIEA_00458	6.59e-28	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HFEONIEA_00459	1.86e-246	-	-	-	-	-	-	-	-
HFEONIEA_00460	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFEONIEA_00461	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HFEONIEA_00462	8.41e-97	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_00463	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HFEONIEA_00464	2.13e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HFEONIEA_00465	1.64e-62	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_00466	3.32e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HFEONIEA_00467	9.18e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HFEONIEA_00468	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
HFEONIEA_00469	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HFEONIEA_00470	1.71e-117	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFEONIEA_00471	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFEONIEA_00472	9.06e-112	-	-	-	-	-	-	-	-
HFEONIEA_00473	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFEONIEA_00474	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HFEONIEA_00475	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HFEONIEA_00476	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HFEONIEA_00477	7.03e-225	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFEONIEA_00478	8.61e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HFEONIEA_00479	2.92e-138	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HFEONIEA_00480	7.29e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFEONIEA_00481	2.79e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFEONIEA_00482	4.84e-125	entB	-	-	Q	-	-	-	Isochorismatase family
HFEONIEA_00483	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HFEONIEA_00484	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFEONIEA_00485	1.97e-277	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HFEONIEA_00486	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HFEONIEA_00487	8.04e-254	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HFEONIEA_00488	1.09e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HFEONIEA_00489	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_00490	6.59e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00491	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFEONIEA_00492	9.77e-231	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFEONIEA_00493	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFEONIEA_00494	8.89e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HFEONIEA_00495	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFEONIEA_00496	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFEONIEA_00497	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFEONIEA_00498	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HFEONIEA_00499	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HFEONIEA_00500	6.17e-201	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFEONIEA_00501	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HFEONIEA_00502	3.13e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFEONIEA_00503	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HFEONIEA_00504	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFEONIEA_00505	2.94e-204	-	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_00506	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HFEONIEA_00507	1.54e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFEONIEA_00508	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
HFEONIEA_00509	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_00510	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HFEONIEA_00511	3.35e-111	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HFEONIEA_00512	2.19e-07	-	-	-	K	-	-	-	transcriptional regulator
HFEONIEA_00513	1.48e-71	-	-	-	-	-	-	-	-
HFEONIEA_00514	2.02e-39	-	-	-	-	-	-	-	-
HFEONIEA_00515	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFEONIEA_00516	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HFEONIEA_00517	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HFEONIEA_00518	2.05e-55	-	-	-	-	-	-	-	-
HFEONIEA_00519	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HFEONIEA_00520	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFEONIEA_00521	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HFEONIEA_00522	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFEONIEA_00523	1.51e-48	-	-	-	-	-	-	-	-
HFEONIEA_00524	5.79e-21	-	-	-	-	-	-	-	-
HFEONIEA_00525	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HFEONIEA_00526	4e-40	-	-	-	S	-	-	-	CsbD-like
HFEONIEA_00527	1.06e-53	-	-	-	-	-	-	-	-
HFEONIEA_00528	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFEONIEA_00529	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HFEONIEA_00530	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFEONIEA_00531	1e-216	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HFEONIEA_00532	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HFEONIEA_00533	1.52e-67	-	-	-	-	-	-	-	-
HFEONIEA_00534	3.23e-58	-	-	-	-	-	-	-	-
HFEONIEA_00535	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFEONIEA_00536	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFEONIEA_00537	2.23e-191	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFEONIEA_00538	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HFEONIEA_00539	1.03e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HFEONIEA_00540	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFEONIEA_00541	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFEONIEA_00542	8.24e-248	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFEONIEA_00543	4.98e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFEONIEA_00544	1.03e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HFEONIEA_00545	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HFEONIEA_00546	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HFEONIEA_00547	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFEONIEA_00548	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HFEONIEA_00549	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFEONIEA_00550	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFEONIEA_00551	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HFEONIEA_00553	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFEONIEA_00554	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_00555	1.84e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFEONIEA_00556	7.56e-109	-	-	-	T	-	-	-	Universal stress protein family
HFEONIEA_00557	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFEONIEA_00558	1.15e-233	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFEONIEA_00559	1.33e-227	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFEONIEA_00560	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HFEONIEA_00561	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFEONIEA_00562	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFEONIEA_00563	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFEONIEA_00565	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFEONIEA_00566	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_00567	3.31e-176	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFEONIEA_00568	3.29e-174	-	-	-	-	-	-	-	-
HFEONIEA_00569	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HFEONIEA_00570	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HFEONIEA_00571	6.41e-111	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HFEONIEA_00572	1.36e-77	-	-	-	-	-	-	-	-
HFEONIEA_00573	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HFEONIEA_00574	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFEONIEA_00575	7.63e-168	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFEONIEA_00576	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFEONIEA_00577	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFEONIEA_00578	2.8e-151	-	-	-	I	-	-	-	phosphatase
HFEONIEA_00579	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFEONIEA_00580	3.54e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFEONIEA_00581	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00582	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFEONIEA_00583	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HFEONIEA_00584	7.48e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HFEONIEA_00585	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HFEONIEA_00586	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFEONIEA_00594	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HFEONIEA_00595	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFEONIEA_00596	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_00597	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFEONIEA_00598	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFEONIEA_00599	2.11e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HFEONIEA_00600	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFEONIEA_00601	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFEONIEA_00602	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFEONIEA_00603	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFEONIEA_00604	2.15e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFEONIEA_00605	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFEONIEA_00606	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFEONIEA_00607	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFEONIEA_00608	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFEONIEA_00609	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFEONIEA_00610	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFEONIEA_00611	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFEONIEA_00612	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFEONIEA_00613	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFEONIEA_00614	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFEONIEA_00615	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFEONIEA_00616	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFEONIEA_00617	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFEONIEA_00618	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFEONIEA_00619	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFEONIEA_00620	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFEONIEA_00621	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFEONIEA_00622	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFEONIEA_00623	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFEONIEA_00624	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFEONIEA_00625	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFEONIEA_00626	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFEONIEA_00627	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFEONIEA_00628	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFEONIEA_00629	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFEONIEA_00630	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFEONIEA_00631	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HFEONIEA_00632	2.19e-111	-	-	-	S	-	-	-	NusG domain II
HFEONIEA_00633	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFEONIEA_00634	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HFEONIEA_00635	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFEONIEA_00636	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFEONIEA_00637	9.96e-212	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFEONIEA_00638	1.68e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFEONIEA_00639	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFEONIEA_00640	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFEONIEA_00641	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFEONIEA_00642	4.92e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFEONIEA_00643	2.46e-235	-	-	-	S	-	-	-	Membrane
HFEONIEA_00644	1.06e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HFEONIEA_00645	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFEONIEA_00646	2.86e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFEONIEA_00647	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HFEONIEA_00648	1.33e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFEONIEA_00649	2.37e-280	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFEONIEA_00650	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFEONIEA_00651	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HFEONIEA_00652	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HFEONIEA_00653	1.89e-255	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_00654	7.77e-197	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFEONIEA_00655	1.18e-169	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFEONIEA_00656	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HFEONIEA_00657	2.11e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFEONIEA_00658	1.18e-66	-	-	-	-	-	-	-	-
HFEONIEA_00659	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFEONIEA_00660	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFEONIEA_00661	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HFEONIEA_00662	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HFEONIEA_00663	3.74e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFEONIEA_00664	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HFEONIEA_00665	2.73e-209	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HFEONIEA_00666	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HFEONIEA_00667	1.19e-233	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HFEONIEA_00668	2.28e-59	-	-	-	K	-	-	-	sequence-specific DNA binding
HFEONIEA_00670	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_00671	1.21e-73	-	-	-	-	-	-	-	-
HFEONIEA_00672	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HFEONIEA_00673	4.8e-83	-	-	-	-	-	-	-	-
HFEONIEA_00674	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HFEONIEA_00675	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00676	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HFEONIEA_00677	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HFEONIEA_00678	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFEONIEA_00679	7.03e-62	-	-	-	-	-	-	-	-
HFEONIEA_00680	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFEONIEA_00681	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFEONIEA_00682	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFEONIEA_00683	4.18e-40	gtcA3	-	-	S	-	-	-	GtrA-like protein
HFEONIEA_00684	6.19e-40	gtcA3	-	-	S	-	-	-	GtrA-like protein
HFEONIEA_00685	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFEONIEA_00686	1.15e-43	-	-	-	-	-	-	-	-
HFEONIEA_00688	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HFEONIEA_00689	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HFEONIEA_00690	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HFEONIEA_00691	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HFEONIEA_00692	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_00693	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HFEONIEA_00694	2.43e-09	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_00695	4.8e-103	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_00696	7.52e-240	-	-	-	S	-	-	-	Cell surface protein
HFEONIEA_00697	1.4e-82	-	-	-	-	-	-	-	-
HFEONIEA_00698	0.0	-	-	-	-	-	-	-	-
HFEONIEA_00699	2.43e-216	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_00700	2.89e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFEONIEA_00701	6.24e-152	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFEONIEA_00702	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFEONIEA_00703	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HFEONIEA_00704	5.24e-124	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HFEONIEA_00705	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFEONIEA_00706	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HFEONIEA_00707	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFEONIEA_00708	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HFEONIEA_00709	3.53e-227	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HFEONIEA_00710	4.31e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HFEONIEA_00711	2.82e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HFEONIEA_00712	2.95e-300	-	-	-	M	-	-	-	Collagen binding domain
HFEONIEA_00713	0.0	-	-	-	I	-	-	-	acetylesterase activity
HFEONIEA_00714	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFEONIEA_00715	8.58e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HFEONIEA_00716	4.29e-50	-	-	-	-	-	-	-	-
HFEONIEA_00718	1.13e-183	-	-	-	S	-	-	-	zinc-ribbon domain
HFEONIEA_00719	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HFEONIEA_00720	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HFEONIEA_00721	1.24e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HFEONIEA_00722	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_00723	1.05e-133	-	-	-	-	-	-	-	-
HFEONIEA_00724	3.7e-30	-	-	-	-	-	-	-	-
HFEONIEA_00725	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFEONIEA_00726	3.21e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFEONIEA_00727	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFEONIEA_00728	2.59e-107	-	-	-	-	-	-	-	-
HFEONIEA_00729	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HFEONIEA_00730	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFEONIEA_00731	3.1e-54	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFEONIEA_00732	6.69e-97	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFEONIEA_00733	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HFEONIEA_00734	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFEONIEA_00735	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HFEONIEA_00736	0.0	-	-	-	-	-	-	-	-
HFEONIEA_00737	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HFEONIEA_00738	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFEONIEA_00739	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HFEONIEA_00740	1.64e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HFEONIEA_00741	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HFEONIEA_00742	1.44e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFEONIEA_00743	1.61e-221	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFEONIEA_00744	2e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFEONIEA_00745	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HFEONIEA_00746	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HFEONIEA_00747	1.81e-173	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFEONIEA_00748	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFEONIEA_00749	2.34e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFEONIEA_00750	6.3e-169	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HFEONIEA_00751	7.2e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFEONIEA_00752	9.05e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_00753	1.3e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HFEONIEA_00754	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFEONIEA_00755	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HFEONIEA_00756	6.01e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFEONIEA_00757	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HFEONIEA_00758	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HFEONIEA_00759	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HFEONIEA_00760	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HFEONIEA_00761	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HFEONIEA_00762	1.08e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HFEONIEA_00763	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_00764	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HFEONIEA_00765	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HFEONIEA_00766	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFEONIEA_00767	1.84e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HFEONIEA_00768	1.47e-210	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFEONIEA_00769	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFEONIEA_00770	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFEONIEA_00771	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HFEONIEA_00772	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFEONIEA_00773	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFEONIEA_00774	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFEONIEA_00775	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFEONIEA_00776	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFEONIEA_00777	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFEONIEA_00778	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HFEONIEA_00779	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HFEONIEA_00780	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFEONIEA_00781	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFEONIEA_00782	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HFEONIEA_00783	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFEONIEA_00784	1.46e-87	-	-	-	L	-	-	-	nuclease
HFEONIEA_00785	5.22e-229	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HFEONIEA_00786	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFEONIEA_00787	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFEONIEA_00788	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFEONIEA_00789	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFEONIEA_00790	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_00791	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFEONIEA_00792	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFEONIEA_00793	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFEONIEA_00794	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HFEONIEA_00795	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HFEONIEA_00796	1.01e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFEONIEA_00797	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFEONIEA_00798	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFEONIEA_00799	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFEONIEA_00800	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HFEONIEA_00801	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFEONIEA_00802	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HFEONIEA_00803	8.47e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HFEONIEA_00804	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFEONIEA_00805	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HFEONIEA_00806	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFEONIEA_00807	1.11e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFEONIEA_00808	4.95e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HFEONIEA_00809	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HFEONIEA_00810	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFEONIEA_00811	4.1e-176	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HFEONIEA_00812	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFEONIEA_00813	6.9e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HFEONIEA_00814	1.53e-83	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HFEONIEA_00815	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFEONIEA_00816	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFEONIEA_00817	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HFEONIEA_00818	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HFEONIEA_00819	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HFEONIEA_00820	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HFEONIEA_00821	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HFEONIEA_00822	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFEONIEA_00823	3.36e-199	-	-	-	G	-	-	-	Peptidase_C39 like family
HFEONIEA_00825	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFEONIEA_00826	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFEONIEA_00827	3.76e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFEONIEA_00828	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HFEONIEA_00829	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HFEONIEA_00830	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFEONIEA_00831	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFEONIEA_00832	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFEONIEA_00833	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFEONIEA_00834	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HFEONIEA_00835	1.19e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFEONIEA_00836	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFEONIEA_00837	4.33e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HFEONIEA_00838	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HFEONIEA_00839	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HFEONIEA_00840	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HFEONIEA_00841	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HFEONIEA_00845	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFEONIEA_00846	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HFEONIEA_00848	2.1e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFEONIEA_00849	4.49e-196	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFEONIEA_00850	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFEONIEA_00851	2.22e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HFEONIEA_00852	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFEONIEA_00853	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_00854	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HFEONIEA_00855	3.08e-93	-	-	-	K	-	-	-	MarR family
HFEONIEA_00856	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_00857	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFEONIEA_00858	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_00859	2.42e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFEONIEA_00860	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HFEONIEA_00861	2.02e-63	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HFEONIEA_00862	1.61e-36	-	-	-	-	-	-	-	-
HFEONIEA_00863	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HFEONIEA_00864	1.2e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HFEONIEA_00865	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HFEONIEA_00866	1.39e-225	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HFEONIEA_00867	1.84e-142	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HFEONIEA_00868	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFEONIEA_00869	2.95e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HFEONIEA_00870	3.69e-230	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFEONIEA_00871	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFEONIEA_00872	1.08e-71	-	-	-	-	-	-	-	-
HFEONIEA_00873	5.57e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_00874	1.32e-117	-	-	-	L	-	-	-	AAA domain
HFEONIEA_00875	0.0	-	-	-	L	-	-	-	AAA domain
HFEONIEA_00876	2.01e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HFEONIEA_00877	8.61e-272	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFEONIEA_00878	2.09e-60	-	-	-	S	-	-	-	MORN repeat
HFEONIEA_00879	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HFEONIEA_00880	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HFEONIEA_00881	1.95e-116	-	-	-	-	-	-	-	-
HFEONIEA_00882	5.74e-32	-	-	-	-	-	-	-	-
HFEONIEA_00883	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFEONIEA_00884	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFEONIEA_00885	1.31e-188	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HFEONIEA_00886	5.24e-138	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HFEONIEA_00887	8.97e-35	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HFEONIEA_00888	1.49e-61	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HFEONIEA_00889	8.9e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HFEONIEA_00890	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HFEONIEA_00891	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFEONIEA_00892	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFEONIEA_00893	3.51e-80	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction
HFEONIEA_00894	8.93e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFEONIEA_00895	2.63e-63	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFEONIEA_00896	2.17e-43	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFEONIEA_00897	8.38e-120	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HFEONIEA_00898	0.0	-	-	-	M	-	-	-	MucBP domain
HFEONIEA_00899	1.42e-08	-	-	-	-	-	-	-	-
HFEONIEA_00900	1.27e-115	-	-	-	S	-	-	-	AAA domain
HFEONIEA_00901	6.12e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
HFEONIEA_00902	1.88e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_00903	7.94e-220	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00904	0.0	-	-	-	C	-	-	-	FMN_bind
HFEONIEA_00906	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_00907	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFEONIEA_00908	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFEONIEA_00909	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HFEONIEA_00910	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFEONIEA_00911	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFEONIEA_00912	9.05e-55	-	-	-	-	-	-	-	-
HFEONIEA_00913	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HFEONIEA_00914	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFEONIEA_00915	1.65e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFEONIEA_00916	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_00917	1.44e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFEONIEA_00918	1.12e-243	-	-	-	-	-	-	-	-
HFEONIEA_00919	1.33e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HFEONIEA_00920	4.88e-162	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HFEONIEA_00921	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
HFEONIEA_00922	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HFEONIEA_00923	3.33e-64	-	-	-	-	-	-	-	-
HFEONIEA_00924	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFEONIEA_00925	0.0	xylP2	-	-	G	-	-	-	symporter
HFEONIEA_00926	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFEONIEA_00927	3.44e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HFEONIEA_00928	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFEONIEA_00929	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HFEONIEA_00930	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HFEONIEA_00931	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HFEONIEA_00934	9.37e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFEONIEA_00935	6.4e-75	-	-	-	-	-	-	-	-
HFEONIEA_00938	1.98e-40	-	-	-	-	-	-	-	-
HFEONIEA_00941	1.35e-180	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HFEONIEA_00942	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFEONIEA_00943	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_00944	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFEONIEA_00945	5.37e-182	-	-	-	-	-	-	-	-
HFEONIEA_00946	1.33e-77	-	-	-	-	-	-	-	-
HFEONIEA_00947	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFEONIEA_00948	2.1e-41	-	-	-	-	-	-	-	-
HFEONIEA_00949	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HFEONIEA_00950	2.36e-248	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFEONIEA_00951	2.5e-173	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HFEONIEA_00952	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HFEONIEA_00953	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFEONIEA_00954	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFEONIEA_00955	1.99e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFEONIEA_00956	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFEONIEA_00957	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFEONIEA_00958	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFEONIEA_00959	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HFEONIEA_00960	9.8e-133	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFEONIEA_00961	6.31e-38	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFEONIEA_00962	6.29e-76	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFEONIEA_00963	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFEONIEA_00964	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFEONIEA_00965	2.62e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFEONIEA_00966	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFEONIEA_00967	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFEONIEA_00968	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFEONIEA_00969	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFEONIEA_00970	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HFEONIEA_00971	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HFEONIEA_00972	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HFEONIEA_00973	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFEONIEA_00974	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HFEONIEA_00975	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFEONIEA_00976	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_00977	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFEONIEA_00978	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFEONIEA_00979	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HFEONIEA_00980	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFEONIEA_00981	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFEONIEA_00982	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HFEONIEA_00983	6.68e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFEONIEA_00984	6.65e-260	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HFEONIEA_00985	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HFEONIEA_00986	1.34e-52	-	-	-	-	-	-	-	-
HFEONIEA_00987	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFEONIEA_00988	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HFEONIEA_00989	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HFEONIEA_00990	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFEONIEA_00991	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HFEONIEA_00992	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HFEONIEA_00993	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HFEONIEA_00994	7.24e-291	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFEONIEA_00995	2.63e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_00996	2.23e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HFEONIEA_00997	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFEONIEA_00998	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HFEONIEA_00999	1.07e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFEONIEA_01000	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HFEONIEA_01001	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFEONIEA_01002	7.42e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFEONIEA_01003	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFEONIEA_01004	3.3e-301	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HFEONIEA_01005	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFEONIEA_01006	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFEONIEA_01007	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFEONIEA_01008	1.02e-07	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HFEONIEA_01009	9.73e-125	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HFEONIEA_01010	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HFEONIEA_01011	6.23e-183	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFEONIEA_01012	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HFEONIEA_01013	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFEONIEA_01014	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HFEONIEA_01015	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFEONIEA_01016	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01017	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFEONIEA_01018	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HFEONIEA_01019	1.03e-29	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HFEONIEA_01020	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HFEONIEA_01021	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFEONIEA_01022	1.53e-215	-	-	-	GM	-	-	-	NmrA-like family
HFEONIEA_01023	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_01024	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFEONIEA_01025	4.63e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFEONIEA_01026	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFEONIEA_01027	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFEONIEA_01028	2.99e-271	-	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_01029	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFEONIEA_01030	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFEONIEA_01031	4.13e-157	-	-	-	-	-	-	-	-
HFEONIEA_01032	3.64e-233	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HFEONIEA_01033	1.47e-83	-	-	-	-	-	-	-	-
HFEONIEA_01034	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01035	2.63e-242	ynjC	-	-	S	-	-	-	Cell surface protein
HFEONIEA_01036	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HFEONIEA_01037	7.37e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFEONIEA_01038	4.62e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HFEONIEA_01039	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01040	2.85e-243	-	-	-	S	-	-	-	Cell surface protein
HFEONIEA_01041	2.69e-99	-	-	-	-	-	-	-	-
HFEONIEA_01042	0.0	-	-	-	-	-	-	-	-
HFEONIEA_01043	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFEONIEA_01044	7.02e-50	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HFEONIEA_01045	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_01046	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HFEONIEA_01047	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HFEONIEA_01048	2.04e-56	-	-	-	S	-	-	-	Cupredoxin-like domain
HFEONIEA_01049	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFEONIEA_01050	4.59e-270	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HFEONIEA_01051	1.41e-199	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HFEONIEA_01052	1.16e-49	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HFEONIEA_01053	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HFEONIEA_01054	0.0	-	-	-	E	-	-	-	Amino Acid
HFEONIEA_01055	1.01e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFEONIEA_01056	3.27e-91	-	-	-	-	-	-	-	-
HFEONIEA_01058	1.71e-208	yhxD	-	-	IQ	-	-	-	KR domain
HFEONIEA_01059	3.46e-285	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HFEONIEA_01060	1.65e-21	-	-	-	-	-	-	-	-
HFEONIEA_01061	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01062	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_01063	2.31e-277	-	-	-	-	-	-	-	-
HFEONIEA_01064	8.04e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_01065	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HFEONIEA_01066	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HFEONIEA_01067	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
HFEONIEA_01068	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HFEONIEA_01069	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_01070	3.79e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HFEONIEA_01071	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_01072	6.57e-91	-	-	-	-	-	-	-	-
HFEONIEA_01073	8.21e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HFEONIEA_01074	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HFEONIEA_01075	5.23e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFEONIEA_01076	8.73e-282	-	-	-	T	-	-	-	diguanylate cyclase
HFEONIEA_01077	1.35e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HFEONIEA_01078	3.57e-120	-	-	-	-	-	-	-	-
HFEONIEA_01079	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFEONIEA_01080	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HFEONIEA_01081	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFEONIEA_01082	7.68e-45	-	-	-	M	-	-	-	Lysin motif
HFEONIEA_01083	1.43e-56	-	-	-	M	-	-	-	Lysin motif
HFEONIEA_01084	4.61e-101	-	-	-	M	-	-	-	LysM domain
HFEONIEA_01085	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_01086	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
HFEONIEA_01087	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_01088	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_01089	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFEONIEA_01090	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFEONIEA_01091	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFEONIEA_01092	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HFEONIEA_01093	3.84e-316	ymfH	-	-	S	-	-	-	Peptidase M16
HFEONIEA_01094	3.31e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HFEONIEA_01095	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFEONIEA_01096	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HFEONIEA_01097	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFEONIEA_01098	1.08e-289	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFEONIEA_01099	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HFEONIEA_01100	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFEONIEA_01101	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFEONIEA_01102	1.35e-93	-	-	-	-	-	-	-	-
HFEONIEA_01103	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFEONIEA_01104	2.07e-116	-	-	-	-	-	-	-	-
HFEONIEA_01105	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFEONIEA_01106	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFEONIEA_01107	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFEONIEA_01108	8.14e-288	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFEONIEA_01109	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFEONIEA_01110	1.01e-275	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFEONIEA_01111	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HFEONIEA_01112	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFEONIEA_01113	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFEONIEA_01114	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFEONIEA_01115	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFEONIEA_01116	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFEONIEA_01117	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFEONIEA_01118	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFEONIEA_01119	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFEONIEA_01120	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFEONIEA_01121	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFEONIEA_01122	4.91e-143	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFEONIEA_01123	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HFEONIEA_01124	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HFEONIEA_01125	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFEONIEA_01126	2.74e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFEONIEA_01127	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HFEONIEA_01128	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFEONIEA_01129	1.6e-96	-	-	-	-	-	-	-	-
HFEONIEA_01130	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_01131	2.2e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFEONIEA_01132	4.47e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFEONIEA_01133	5.32e-209	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HFEONIEA_01134	8.49e-66	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HFEONIEA_01135	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HFEONIEA_01136	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFEONIEA_01137	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HFEONIEA_01138	1.65e-26	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HFEONIEA_01139	4.85e-193	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HFEONIEA_01140	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HFEONIEA_01141	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HFEONIEA_01142	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HFEONIEA_01143	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HFEONIEA_01145	3.84e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HFEONIEA_01146	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFEONIEA_01147	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFEONIEA_01148	4.75e-150	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFEONIEA_01149	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFEONIEA_01150	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HFEONIEA_01151	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFEONIEA_01152	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HFEONIEA_01153	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HFEONIEA_01154	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFEONIEA_01155	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HFEONIEA_01156	9.13e-53	-	-	-	-	-	-	-	-
HFEONIEA_01157	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HFEONIEA_01158	1.27e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HFEONIEA_01160	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HFEONIEA_01161	6.91e-119	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFEONIEA_01162	1.7e-67	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFEONIEA_01163	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFEONIEA_01164	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFEONIEA_01165	5.01e-65	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HFEONIEA_01166	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HFEONIEA_01167	5.34e-214	mleR	-	-	K	-	-	-	LysR family
HFEONIEA_01168	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HFEONIEA_01169	9.09e-213	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HFEONIEA_01170	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFEONIEA_01171	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFEONIEA_01172	2.48e-32	-	-	-	-	-	-	-	-
HFEONIEA_01173	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HFEONIEA_01174	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HFEONIEA_01175	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HFEONIEA_01176	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFEONIEA_01177	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFEONIEA_01178	3.13e-207	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HFEONIEA_01179	1.98e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFEONIEA_01180	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HFEONIEA_01181	6.39e-234	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HFEONIEA_01182	8.04e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HFEONIEA_01183	8.19e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFEONIEA_01184	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HFEONIEA_01185	5.68e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFEONIEA_01186	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFEONIEA_01187	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFEONIEA_01188	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HFEONIEA_01189	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFEONIEA_01190	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFEONIEA_01191	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFEONIEA_01192	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HFEONIEA_01193	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFEONIEA_01194	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_01195	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HFEONIEA_01196	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_01197	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_01198	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HFEONIEA_01199	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFEONIEA_01200	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HFEONIEA_01201	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HFEONIEA_01202	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HFEONIEA_01203	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HFEONIEA_01205	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HFEONIEA_01206	1.56e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_01207	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_01209	7.62e-97	-	-	-	-	-	-	-	-
HFEONIEA_01210	2.9e-139	-	-	-	-	-	-	-	-
HFEONIEA_01211	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFEONIEA_01212	1.15e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HFEONIEA_01213	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFEONIEA_01214	3.02e-201	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFEONIEA_01215	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFEONIEA_01216	2.31e-95	-	-	-	M	-	-	-	LysM domain protein
HFEONIEA_01217	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HFEONIEA_01218	5.01e-226	-	-	-	-	-	-	-	-
HFEONIEA_01219	2.8e-169	-	-	-	-	-	-	-	-
HFEONIEA_01220	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HFEONIEA_01221	1.96e-73	-	-	-	-	-	-	-	-
HFEONIEA_01222	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFEONIEA_01223	2.98e-99	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HFEONIEA_01224	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_01225	1.17e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFEONIEA_01226	1.79e-52	-	-	-	-	-	-	-	-
HFEONIEA_01227	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_01228	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_01229	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_01230	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFEONIEA_01231	4.3e-124	-	-	-	K	-	-	-	Cupin domain
HFEONIEA_01232	8.08e-110	-	-	-	S	-	-	-	ASCH
HFEONIEA_01233	1.88e-111	-	-	-	K	-	-	-	GNAT family
HFEONIEA_01234	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HFEONIEA_01235	2.06e-30	-	-	-	-	-	-	-	-
HFEONIEA_01236	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HFEONIEA_01237	2.16e-207	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_01238	1.08e-243	-	-	-	-	-	-	-	-
HFEONIEA_01239	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HFEONIEA_01240	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HFEONIEA_01242	2.06e-256	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HFEONIEA_01243	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HFEONIEA_01244	7.28e-42	-	-	-	-	-	-	-	-
HFEONIEA_01245	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFEONIEA_01246	6.4e-54	-	-	-	-	-	-	-	-
HFEONIEA_01247	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HFEONIEA_01248	2.48e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFEONIEA_01249	6.71e-80	-	-	-	S	-	-	-	CHY zinc finger
HFEONIEA_01250	1.33e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFEONIEA_01251	3.7e-279	-	-	-	-	-	-	-	-
HFEONIEA_01252	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HFEONIEA_01253	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HFEONIEA_01254	3.93e-59	-	-	-	-	-	-	-	-
HFEONIEA_01255	2.39e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HFEONIEA_01256	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFEONIEA_01257	1.17e-305	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HFEONIEA_01258	1.56e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFEONIEA_01259	8.95e-60	-	-	-	-	-	-	-	-
HFEONIEA_01260	6.06e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFEONIEA_01261	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HFEONIEA_01262	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HFEONIEA_01263	1.08e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HFEONIEA_01264	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HFEONIEA_01265	1.61e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HFEONIEA_01266	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HFEONIEA_01267	1.25e-102	-	-	-	-	-	-	-	-
HFEONIEA_01268	9.88e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFEONIEA_01269	3.66e-224	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HFEONIEA_01270	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_01271	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HFEONIEA_01272	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFEONIEA_01273	4.47e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01274	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFEONIEA_01275	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFEONIEA_01276	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HFEONIEA_01277	1.24e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFEONIEA_01278	0.0	-	-	-	M	-	-	-	domain protein
HFEONIEA_01289	5.4e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HFEONIEA_01290	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HFEONIEA_01291	1.25e-124	-	-	-	-	-	-	-	-
HFEONIEA_01292	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_01293	2.52e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HFEONIEA_01295	6.28e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFEONIEA_01296	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HFEONIEA_01297	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFEONIEA_01298	2.75e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HFEONIEA_01299	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFEONIEA_01300	2.75e-156	-	-	-	-	-	-	-	-
HFEONIEA_01301	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFEONIEA_01302	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_01303	1.76e-309	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HFEONIEA_01305	6.7e-23	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HFEONIEA_01306	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HFEONIEA_01307	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFEONIEA_01308	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFEONIEA_01309	9.32e-40	-	-	-	-	-	-	-	-
HFEONIEA_01310	7.15e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HFEONIEA_01311	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HFEONIEA_01312	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFEONIEA_01313	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFEONIEA_01314	2.05e-175	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFEONIEA_01315	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFEONIEA_01316	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HFEONIEA_01317	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFEONIEA_01318	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HFEONIEA_01319	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFEONIEA_01320	7.19e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_01321	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFEONIEA_01322	1.56e-161	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFEONIEA_01323	3.43e-154	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HFEONIEA_01324	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFEONIEA_01325	0.0	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HFEONIEA_01327	3.63e-164	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HFEONIEA_01328	7.5e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_01329	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HFEONIEA_01330	2.95e-199	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFEONIEA_01331	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_01332	5.71e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_01333	1.55e-203	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFEONIEA_01334	8.04e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFEONIEA_01335	7.83e-140	-	-	-	-	-	-	-	-
HFEONIEA_01336	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFEONIEA_01337	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFEONIEA_01338	5.37e-74	-	-	-	-	-	-	-	-
HFEONIEA_01339	4.56e-78	-	-	-	-	-	-	-	-
HFEONIEA_01340	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFEONIEA_01341	8.98e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_01342	8.82e-119	-	-	-	-	-	-	-	-
HFEONIEA_01343	7.12e-62	-	-	-	-	-	-	-	-
HFEONIEA_01344	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HFEONIEA_01347	4.29e-87	-	-	-	-	-	-	-	-
HFEONIEA_01348	9.03e-16	-	-	-	-	-	-	-	-
HFEONIEA_01349	2.25e-236	-	-	-	-	-	-	-	-
HFEONIEA_01350	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFEONIEA_01351	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HFEONIEA_01352	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HFEONIEA_01353	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFEONIEA_01354	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HFEONIEA_01355	4.24e-291	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HFEONIEA_01356	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HFEONIEA_01357	2.97e-224	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HFEONIEA_01358	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HFEONIEA_01359	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HFEONIEA_01360	2.69e-316	dinF	-	-	V	-	-	-	MatE
HFEONIEA_01361	3.09e-43	-	-	-	-	-	-	-	-
HFEONIEA_01364	3.48e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HFEONIEA_01365	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFEONIEA_01366	3.81e-105	-	-	-	-	-	-	-	-
HFEONIEA_01367	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HFEONIEA_01368	6.25e-138	-	-	-	-	-	-	-	-
HFEONIEA_01369	0.0	celR	-	-	K	-	-	-	PRD domain
HFEONIEA_01370	2.7e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HFEONIEA_01371	1.55e-16	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HFEONIEA_01372	1.19e-36	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HFEONIEA_01373	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFEONIEA_01374	1.23e-309	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_01375	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_01376	3e-272	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HFEONIEA_01377	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFEONIEA_01378	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFEONIEA_01379	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HFEONIEA_01380	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HFEONIEA_01381	1.08e-268	arcT	-	-	E	-	-	-	Aminotransferase
HFEONIEA_01382	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFEONIEA_01383	2.43e-18	-	-	-	-	-	-	-	-
HFEONIEA_01384	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFEONIEA_01385	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFEONIEA_01386	1.49e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HFEONIEA_01387	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFEONIEA_01388	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFEONIEA_01389	3.57e-195	-	-	-	-	-	-	-	-
HFEONIEA_01390	4.02e-62	-	-	-	-	-	-	-	-
HFEONIEA_01391	6.84e-199	-	-	-	M	-	-	-	Peptidase family S41
HFEONIEA_01392	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_01393	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFEONIEA_01394	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFEONIEA_01395	4.43e-129	-	-	-	-	-	-	-	-
HFEONIEA_01396	4.08e-101	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HFEONIEA_01397	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HFEONIEA_01398	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFEONIEA_01399	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HFEONIEA_01400	0.0	-	-	-	S	-	-	-	membrane
HFEONIEA_01401	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFEONIEA_01402	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HFEONIEA_01403	3.09e-286	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HFEONIEA_01404	3.24e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFEONIEA_01405	0.0	-	-	-	-	-	-	-	-
HFEONIEA_01406	0.0	-	-	-	-	-	-	-	-
HFEONIEA_01407	0.0	-	2.4.1.12	GT2	M	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	PilZ domain
HFEONIEA_01408	1.92e-206	-	-	-	M	-	-	-	GtrA-like protein
HFEONIEA_01409	5.4e-54	-	-	-	K	-	-	-	transcriptional regulator
HFEONIEA_01410	9.13e-80	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HFEONIEA_01411	3.39e-138	-	-	-	-	-	-	-	-
HFEONIEA_01412	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HFEONIEA_01413	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_01414	7.06e-307	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HFEONIEA_01415	0.0	-	-	-	-	-	-	-	-
HFEONIEA_01416	1.65e-80	-	-	-	-	-	-	-	-
HFEONIEA_01417	2.76e-247	-	-	-	S	-	-	-	Fn3-like domain
HFEONIEA_01418	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01419	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01420	1.55e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFEONIEA_01421	6.76e-73	-	-	-	-	-	-	-	-
HFEONIEA_01422	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HFEONIEA_01423	4.47e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01424	9.53e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_01425	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HFEONIEA_01426	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFEONIEA_01427	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFEONIEA_01428	1.69e-144	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFEONIEA_01429	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFEONIEA_01430	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFEONIEA_01431	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HFEONIEA_01432	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HFEONIEA_01433	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HFEONIEA_01434	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HFEONIEA_01435	7.08e-309	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HFEONIEA_01436	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFEONIEA_01437	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HFEONIEA_01438	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HFEONIEA_01439	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFEONIEA_01440	8.54e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFEONIEA_01441	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFEONIEA_01442	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFEONIEA_01443	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFEONIEA_01444	9.54e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFEONIEA_01445	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFEONIEA_01446	5.04e-312	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HFEONIEA_01447	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFEONIEA_01448	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFEONIEA_01449	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFEONIEA_01450	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFEONIEA_01451	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFEONIEA_01452	4.59e-73	-	-	-	-	-	-	-	-
HFEONIEA_01453	1.16e-305	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HFEONIEA_01454	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFEONIEA_01455	1.35e-82	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFEONIEA_01456	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFEONIEA_01457	1.9e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HFEONIEA_01458	6.32e-114	-	-	-	-	-	-	-	-
HFEONIEA_01459	3.3e-126	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HFEONIEA_01460	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HFEONIEA_01461	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HFEONIEA_01462	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFEONIEA_01463	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HFEONIEA_01464	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFEONIEA_01465	1.91e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HFEONIEA_01466	1.09e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFEONIEA_01467	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HFEONIEA_01468	6.17e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFEONIEA_01469	1.13e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFEONIEA_01470	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFEONIEA_01471	5.16e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFEONIEA_01472	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HFEONIEA_01473	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFEONIEA_01474	1.59e-217	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HFEONIEA_01475	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HFEONIEA_01476	3.35e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFEONIEA_01477	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFEONIEA_01478	1.63e-207	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFEONIEA_01479	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFEONIEA_01480	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFEONIEA_01481	3.46e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFEONIEA_01482	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFEONIEA_01483	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFEONIEA_01484	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFEONIEA_01485	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFEONIEA_01486	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HFEONIEA_01487	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFEONIEA_01488	9.3e-144	-	-	-	S	-	-	-	membrane
HFEONIEA_01489	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFEONIEA_01490	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HFEONIEA_01491	0.0	-	-	-	S	-	-	-	membrane
HFEONIEA_01492	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFEONIEA_01493	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFEONIEA_01494	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFEONIEA_01495	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HFEONIEA_01496	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HFEONIEA_01497	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HFEONIEA_01498	1.56e-139	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HFEONIEA_01499	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HFEONIEA_01500	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HFEONIEA_01501	2.23e-178	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HFEONIEA_01502	1.33e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFEONIEA_01503	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HFEONIEA_01504	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFEONIEA_01505	1.77e-205	-	-	-	-	-	-	-	-
HFEONIEA_01506	1.15e-202	-	-	-	-	-	-	-	-
HFEONIEA_01507	3.55e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
HFEONIEA_01508	5.16e-72	-	-	-	-	-	-	-	-
HFEONIEA_01509	2.97e-41	-	-	-	-	-	-	-	-
HFEONIEA_01513	9.81e-27	-	-	-	-	-	-	-	-
HFEONIEA_01514	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_01515	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFEONIEA_01516	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HFEONIEA_01517	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFEONIEA_01518	5.49e-242	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFEONIEA_01519	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFEONIEA_01520	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HFEONIEA_01521	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFEONIEA_01522	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFEONIEA_01523	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFEONIEA_01524	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFEONIEA_01525	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFEONIEA_01526	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HFEONIEA_01527	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFEONIEA_01528	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFEONIEA_01529	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01530	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_01531	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFEONIEA_01532	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFEONIEA_01533	1.19e-73	-	-	-	-	-	-	-	-
HFEONIEA_01534	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFEONIEA_01535	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFEONIEA_01536	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFEONIEA_01537	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFEONIEA_01538	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFEONIEA_01539	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFEONIEA_01540	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFEONIEA_01541	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFEONIEA_01542	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFEONIEA_01543	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFEONIEA_01544	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFEONIEA_01545	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFEONIEA_01546	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFEONIEA_01547	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HFEONIEA_01548	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFEONIEA_01549	3.09e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFEONIEA_01550	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFEONIEA_01551	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFEONIEA_01552	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFEONIEA_01553	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFEONIEA_01554	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFEONIEA_01555	9.38e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFEONIEA_01556	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFEONIEA_01557	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HFEONIEA_01558	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFEONIEA_01559	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFEONIEA_01560	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFEONIEA_01561	3.2e-70	-	-	-	-	-	-	-	-
HFEONIEA_01562	2.94e-149	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFEONIEA_01563	1.19e-111	cps3I	-	-	G	-	-	-	Acyltransferase family
HFEONIEA_01564	4.61e-128	cps3I	-	-	G	-	-	-	Acyltransferase family
HFEONIEA_01565	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HFEONIEA_01566	1.82e-239	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFEONIEA_01567	6.57e-42	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFEONIEA_01568	2.78e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HFEONIEA_01569	1.06e-68	-	-	-	-	-	-	-	-
HFEONIEA_01570	6.01e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HFEONIEA_01571	1.6e-40	-	-	-	-	-	-	-	-
HFEONIEA_01572	1.64e-35	-	-	-	-	-	-	-	-
HFEONIEA_01574	5.45e-168	-	-	-	-	-	-	-	-
HFEONIEA_01575	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HFEONIEA_01576	1.34e-137	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HFEONIEA_01577	4.59e-171	lytE	-	-	M	-	-	-	NlpC/P60 family
HFEONIEA_01578	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HFEONIEA_01579	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HFEONIEA_01580	1.83e-165	pbpX	-	-	V	-	-	-	Beta-lactamase
HFEONIEA_01581	1.04e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFEONIEA_01582	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HFEONIEA_01583	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HFEONIEA_01584	2.63e-288	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HFEONIEA_01585	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFEONIEA_01586	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HFEONIEA_01587	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFEONIEA_01588	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFEONIEA_01589	0.0	-	-	-	-	-	-	-	-
HFEONIEA_01590	1.43e-250	-	-	-	M	-	-	-	MucBP domain
HFEONIEA_01591	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_01592	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFEONIEA_01593	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HFEONIEA_01594	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFEONIEA_01595	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFEONIEA_01596	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFEONIEA_01597	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFEONIEA_01598	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFEONIEA_01599	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFEONIEA_01600	2.5e-132	-	-	-	L	-	-	-	Integrase
HFEONIEA_01601	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFEONIEA_01602	5.6e-41	-	-	-	-	-	-	-	-
HFEONIEA_01603	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HFEONIEA_01604	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFEONIEA_01605	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFEONIEA_01606	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFEONIEA_01607	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFEONIEA_01608	5.39e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFEONIEA_01609	3.5e-292	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFEONIEA_01610	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HFEONIEA_01611	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFEONIEA_01612	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HFEONIEA_01613	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFEONIEA_01614	1.27e-143	-	-	-	-	-	-	-	-
HFEONIEA_01615	2.18e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFEONIEA_01616	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HFEONIEA_01617	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFEONIEA_01618	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFEONIEA_01619	8.28e-127	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_01620	1.46e-49	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_01621	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFEONIEA_01622	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HFEONIEA_01623	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFEONIEA_01624	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01625	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HFEONIEA_01626	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HFEONIEA_01627	7.85e-36	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HFEONIEA_01628	9.37e-66	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HFEONIEA_01629	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFEONIEA_01630	2.1e-114	-	-	-	S	-	-	-	Membrane
HFEONIEA_01631	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFEONIEA_01632	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HFEONIEA_01633	4.82e-258	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_01634	4.18e-162	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFEONIEA_01635	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HFEONIEA_01636	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HFEONIEA_01637	5e-130	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFEONIEA_01638	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HFEONIEA_01639	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_01640	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFEONIEA_01641	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFEONIEA_01643	7.51e-77	-	-	-	M	-	-	-	LysM domain
HFEONIEA_01644	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HFEONIEA_01645	4.36e-25	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFEONIEA_01646	9.34e-30	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFEONIEA_01647	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_01648	9.52e-175	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HFEONIEA_01649	4.48e-178	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFEONIEA_01650	8.9e-147	-	-	-	C	-	-	-	Aldo keto reductase
HFEONIEA_01651	2.11e-148	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_01652	2e-27	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_01653	5.16e-32	-	-	-	C	-	-	-	Flavodoxin
HFEONIEA_01655	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_01656	5.54e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFEONIEA_01657	2.89e-108	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_01658	1.96e-119	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFEONIEA_01659	3.24e-159	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HFEONIEA_01660	1.64e-95	-	-	-	C	-	-	-	Flavodoxin
HFEONIEA_01661	3.56e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFEONIEA_01662	1.15e-179	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFEONIEA_01663	2.38e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFEONIEA_01664	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HFEONIEA_01665	1.46e-133	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_01666	7.79e-203	-	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_01667	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HFEONIEA_01668	2.22e-144	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HFEONIEA_01669	2.81e-64	-	-	-	-	-	-	-	-
HFEONIEA_01670	9.76e-50	-	-	-	-	-	-	-	-
HFEONIEA_01671	6.25e-112	yvbK	-	-	K	-	-	-	GNAT family
HFEONIEA_01672	8.4e-112	-	-	-	-	-	-	-	-
HFEONIEA_01673	2.15e-144	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFEONIEA_01674	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFEONIEA_01675	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFEONIEA_01676	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFEONIEA_01678	4.97e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01679	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFEONIEA_01680	6.98e-160	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFEONIEA_01681	6.11e-125	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFEONIEA_01682	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HFEONIEA_01683	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HFEONIEA_01684	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HFEONIEA_01685	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_01686	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFEONIEA_01687	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_01688	3.37e-35	-	-	-	-	-	-	-	-
HFEONIEA_01689	2.82e-120	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
HFEONIEA_01690	1.4e-116	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
HFEONIEA_01692	1.15e-100	repA	-	-	S	-	-	-	Replication initiator protein A
HFEONIEA_01693	1.35e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HFEONIEA_01694	3.2e-37	-	-	-	-	-	-	-	-
HFEONIEA_01695	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HFEONIEA_01697	2.06e-104	-	-	-	-	-	-	-	-
HFEONIEA_01698	4.45e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
HFEONIEA_01699	8.94e-70	-	-	-	-	-	-	-	-
HFEONIEA_01700	4.48e-152	-	-	-	-	-	-	-	-
HFEONIEA_01701	0.0	traE	-	-	U	-	-	-	Psort location Cytoplasmic, score
HFEONIEA_01702	0.0	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HFEONIEA_01703	2.26e-208	-	-	-	M	-	-	-	CHAP domain
HFEONIEA_01704	2.17e-76	-	-	-	-	-	-	-	-
HFEONIEA_01705	9.67e-59	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HFEONIEA_01706	3.88e-87	-	-	-	-	-	-	-	-
HFEONIEA_01707	1.07e-293	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HFEONIEA_01709	6.64e-95	-	-	-	-	-	-	-	-
HFEONIEA_01710	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFEONIEA_01711	4.22e-41	-	-	-	-	-	-	-	-
HFEONIEA_01712	1.98e-58	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFEONIEA_01713	9.15e-117	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HFEONIEA_01714	2.21e-46	-	-	-	-	-	-	-	-
HFEONIEA_01715	6.01e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFEONIEA_01716	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HFEONIEA_01717	7.47e-164	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFEONIEA_01718	1.03e-40	-	-	-	-	-	-	-	-
HFEONIEA_01719	2.21e-28	-	-	-	-	-	-	-	-
HFEONIEA_01720	9.15e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HFEONIEA_01721	3.31e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFEONIEA_01722	1.86e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HFEONIEA_01723	4.07e-246	-	-	-	C	-	-	-	Aldo/keto reductase family
HFEONIEA_01725	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_01726	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_01727	3.7e-313	-	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_01730	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HFEONIEA_01731	3.6e-140	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HFEONIEA_01732	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_01733	9.88e-110	repA	-	-	S	-	-	-	Replication initiator protein A
HFEONIEA_01734	4.78e-42	-	-	-	-	-	-	-	-
HFEONIEA_01735	5.5e-56	-	-	-	-	-	-	-	-
HFEONIEA_01736	3.99e-36	-	-	-	-	-	-	-	-
HFEONIEA_01737	0.0	traA	-	-	L	-	-	-	MobA/MobL family
HFEONIEA_01738	8.58e-179	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HFEONIEA_01739	2.97e-117	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFEONIEA_01740	2.6e-66	-	-	-	V	-	-	-	VanZ like family
HFEONIEA_01741	1.04e-130	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFEONIEA_01742	2.69e-56	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HFEONIEA_01743	3.59e-50	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HFEONIEA_01744	1.36e-17	-	-	-	S	-	-	-	glycosyl transferase family 2
HFEONIEA_01745	2.42e-27	epsJ1	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HFEONIEA_01746	9.4e-122	-	-	-	L	-	-	-	4.5 Transposon and IS
HFEONIEA_01747	7.06e-42	-	-	-	L	ko:K07483	-	ko00000	Transposase
HFEONIEA_01748	2.52e-165	epsB	-	-	M	-	-	-	biosynthesis protein
HFEONIEA_01749	2.76e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HFEONIEA_01750	7.29e-170	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HFEONIEA_01751	7.33e-34	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HFEONIEA_01752	4.29e-102	-	-	GT2	V	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase, family 2
HFEONIEA_01754	8.35e-36	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HFEONIEA_01755	5.69e-15	-	-	-	S	ko:K16710	-	ko00000	slime layer polysaccharide biosynthetic process
HFEONIEA_01756	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFEONIEA_01757	2.5e-132	-	-	-	L	-	-	-	Integrase
HFEONIEA_01758	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFEONIEA_01759	5.6e-41	-	-	-	-	-	-	-	-
HFEONIEA_01760	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HFEONIEA_01761	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFEONIEA_01762	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFEONIEA_01763	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFEONIEA_01764	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFEONIEA_01765	5.39e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFEONIEA_01766	3.5e-292	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFEONIEA_01767	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HFEONIEA_01768	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFEONIEA_01769	1.51e-173	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HFEONIEA_01771	1.29e-227	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFEONIEA_01773	7.83e-127	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HFEONIEA_01774	4.3e-164	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	Transporter
HFEONIEA_01775	5.93e-237	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HFEONIEA_01776	5.16e-308	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFEONIEA_01777	6.96e-20	-	-	-	S	-	-	-	Transglycosylase associated protein
HFEONIEA_01778	1.06e-143	-	-	-	KT	-	-	-	Purine catabolism regulatory protein-like family
HFEONIEA_01779	9.28e-209	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HFEONIEA_01780	6.42e-205	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HFEONIEA_01781	5.32e-255	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
HFEONIEA_01782	2.83e-53	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFEONIEA_01783	4.31e-83	-	-	-	-	-	-	-	-
HFEONIEA_01784	4.54e-70	-	-	-	-	-	-	-	-
HFEONIEA_01785	9.6e-317	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HFEONIEA_01786	5.04e-183	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HFEONIEA_01787	3.04e-260	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HFEONIEA_01788	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFEONIEA_01789	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_01790	1.92e-17	-	-	-	S	-	-	-	FRG
HFEONIEA_01791	7.55e-53	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HFEONIEA_01792	0.0	-	-	-	M	-	-	-	domain protein
HFEONIEA_01793	2.51e-137	-	-	-	L	-	-	-	Resolvase, N terminal domain
HFEONIEA_01794	2.61e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFEONIEA_01795	3.66e-98	-	-	-	L	-	-	-	Transposase DDE domain
HFEONIEA_01798	2.39e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HFEONIEA_01800	1.16e-66	repA	-	-	S	-	-	-	Replication initiator protein A
HFEONIEA_01801	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HFEONIEA_01802	1.51e-85	-	-	-	-	-	-	-	-
HFEONIEA_01803	1.34e-70	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HFEONIEA_01804	5.98e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HFEONIEA_01805	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
HFEONIEA_01806	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HFEONIEA_01807	4.41e-248	-	-	-	V	-	-	-	Beta-lactamase
HFEONIEA_01808	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HFEONIEA_01809	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFEONIEA_01810	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HFEONIEA_01811	7.39e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
HFEONIEA_01812	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HFEONIEA_01813	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HFEONIEA_01814	4.29e-101	-	-	-	-	-	-	-	-
HFEONIEA_01815	1.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFEONIEA_01816	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HFEONIEA_01817	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HFEONIEA_01819	2.82e-161	-	-	-	S	-	-	-	YjbR
HFEONIEA_01820	9.53e-285	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HFEONIEA_01821	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFEONIEA_01822	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HFEONIEA_01823	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
HFEONIEA_01824	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFEONIEA_01825	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFEONIEA_01826	2.48e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_01827	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HFEONIEA_01828	1.36e-209	-	-	-	GM	-	-	-	NmrA-like family
HFEONIEA_01829	4.31e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HFEONIEA_01830	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HFEONIEA_01831	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HFEONIEA_01832	1.7e-70	-	-	-	-	-	-	-	-
HFEONIEA_01833	2.88e-274	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HFEONIEA_01834	2.11e-82	-	-	-	-	-	-	-	-
HFEONIEA_01835	1.36e-112	-	-	-	-	-	-	-	-
HFEONIEA_01836	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFEONIEA_01837	2.27e-74	-	-	-	-	-	-	-	-
HFEONIEA_01838	2.37e-21	-	-	-	-	-	-	-	-
HFEONIEA_01839	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HFEONIEA_01840	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HFEONIEA_01841	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HFEONIEA_01842	2.66e-155	-	-	-	S	-	-	-	membrane
HFEONIEA_01843	2.55e-145	-	-	-	S	-	-	-	VIT family
HFEONIEA_01844	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HFEONIEA_01845	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFEONIEA_01846	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HFEONIEA_01847	4.26e-54	-	-	-	-	-	-	-	-
HFEONIEA_01848	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HFEONIEA_01849	7.21e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HFEONIEA_01850	7.21e-35	-	-	-	-	-	-	-	-
HFEONIEA_01851	2.55e-65	-	-	-	-	-	-	-	-
HFEONIEA_01852	7.2e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HFEONIEA_01853	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HFEONIEA_01854	2.52e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HFEONIEA_01855	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFEONIEA_01856	1.18e-98	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFEONIEA_01857	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HFEONIEA_01858	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HFEONIEA_01859	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFEONIEA_01860	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFEONIEA_01861	3.9e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HFEONIEA_01862	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFEONIEA_01863	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFEONIEA_01864	3.68e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFEONIEA_01865	5.43e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFEONIEA_01866	4.88e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HFEONIEA_01867	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HFEONIEA_01868	1.58e-66	-	-	-	-	-	-	-	-
HFEONIEA_01869	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HFEONIEA_01870	1.94e-76	-	-	-	-	-	-	-	-
HFEONIEA_01871	0.0	-	-	-	-	-	-	-	-
HFEONIEA_01872	7.53e-88	-	-	-	-	-	-	-	-
HFEONIEA_01873	3.91e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFEONIEA_01874	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01875	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HFEONIEA_01876	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFEONIEA_01877	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_01878	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HFEONIEA_01879	4.45e-38	-	-	-	-	-	-	-	-
HFEONIEA_01880	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HFEONIEA_01881	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HFEONIEA_01882	6.18e-71	-	-	-	-	-	-	-	-
HFEONIEA_01883	9.96e-82	-	-	-	-	-	-	-	-
HFEONIEA_01885	6.97e-68	-	-	-	-	-	-	-	-
HFEONIEA_01886	4.99e-52	-	-	-	-	-	-	-	-
HFEONIEA_01887	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HFEONIEA_01888	7.98e-205	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HFEONIEA_01889	4.93e-129	-	-	-	K	-	-	-	transcriptional regulator
HFEONIEA_01890	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HFEONIEA_01891	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFEONIEA_01892	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HFEONIEA_01893	6.12e-148	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFEONIEA_01894	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HFEONIEA_01895	1.91e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFEONIEA_01896	9.52e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HFEONIEA_01897	6.85e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HFEONIEA_01898	1.03e-16	-	-	-	-	-	-	-	-
HFEONIEA_01899	2.03e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HFEONIEA_01900	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HFEONIEA_01901	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HFEONIEA_01902	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFEONIEA_01903	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFEONIEA_01904	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HFEONIEA_01905	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HFEONIEA_01906	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HFEONIEA_01907	1.75e-159	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01908	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HFEONIEA_01909	7.83e-60	-	-	-	-	-	-	-	-
HFEONIEA_01910	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HFEONIEA_01911	1.03e-65	-	-	-	-	-	-	-	-
HFEONIEA_01912	1.87e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
HFEONIEA_01913	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
HFEONIEA_01914	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFEONIEA_01915	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HFEONIEA_01916	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFEONIEA_01917	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFEONIEA_01918	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HFEONIEA_01919	2.74e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_01920	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HFEONIEA_01921	5.63e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HFEONIEA_01922	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HFEONIEA_01923	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HFEONIEA_01924	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFEONIEA_01925	3.9e-143	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFEONIEA_01926	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HFEONIEA_01927	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_01928	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HFEONIEA_01929	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFEONIEA_01930	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFEONIEA_01931	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HFEONIEA_01932	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HFEONIEA_01933	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HFEONIEA_01934	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFEONIEA_01935	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFEONIEA_01936	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_01937	1.48e-247	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HFEONIEA_01938	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HFEONIEA_01939	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFEONIEA_01940	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFEONIEA_01941	2.11e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HFEONIEA_01942	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFEONIEA_01943	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFEONIEA_01944	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_01945	1.2e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFEONIEA_01946	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFEONIEA_01947	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HFEONIEA_01948	1.86e-210	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HFEONIEA_01949	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFEONIEA_01950	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_01951	2.09e-83	-	-	-	-	-	-	-	-
HFEONIEA_01952	2.53e-198	estA	-	-	S	-	-	-	Putative esterase
HFEONIEA_01953	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HFEONIEA_01954	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_01955	2.81e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFEONIEA_01956	1.69e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HFEONIEA_01957	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFEONIEA_01958	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_01959	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_01960	1.02e-197	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFEONIEA_01961	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_01962	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_01963	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_01964	1.85e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFEONIEA_01965	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFEONIEA_01966	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFEONIEA_01967	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFEONIEA_01968	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HFEONIEA_01970	2.83e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFEONIEA_01971	7.09e-184	yxeH	-	-	S	-	-	-	hydrolase
HFEONIEA_01972	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFEONIEA_01973	4.13e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFEONIEA_01974	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HFEONIEA_01975	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HFEONIEA_01976	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFEONIEA_01977	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFEONIEA_01978	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFEONIEA_01979	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HFEONIEA_01980	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HFEONIEA_01981	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFEONIEA_01982	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFEONIEA_01983	8.73e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HFEONIEA_01984	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFEONIEA_01985	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFEONIEA_01986	2.78e-132	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HFEONIEA_01987	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HFEONIEA_01988	3.04e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFEONIEA_01989	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HFEONIEA_01990	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFEONIEA_01991	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_01992	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HFEONIEA_01993	6.53e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HFEONIEA_01994	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HFEONIEA_01995	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HFEONIEA_01996	1.06e-16	-	-	-	-	-	-	-	-
HFEONIEA_01997	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HFEONIEA_01998	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HFEONIEA_01999	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HFEONIEA_02000	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFEONIEA_02001	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFEONIEA_02002	9.62e-19	-	-	-	-	-	-	-	-
HFEONIEA_02003	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HFEONIEA_02004	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HFEONIEA_02006	1.14e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HFEONIEA_02007	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFEONIEA_02008	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02009	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFEONIEA_02010	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HFEONIEA_02011	5.04e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HFEONIEA_02012	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HFEONIEA_02013	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HFEONIEA_02014	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HFEONIEA_02015	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HFEONIEA_02016	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HFEONIEA_02017	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFEONIEA_02018	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFEONIEA_02019	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HFEONIEA_02020	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HFEONIEA_02021	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HFEONIEA_02022	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HFEONIEA_02023	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HFEONIEA_02024	1e-180	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HFEONIEA_02025	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_02026	4.02e-203	degV1	-	-	S	-	-	-	DegV family
HFEONIEA_02027	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HFEONIEA_02028	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HFEONIEA_02030	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFEONIEA_02031	0.0	-	-	-	-	-	-	-	-
HFEONIEA_02033	9.06e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HFEONIEA_02034	1.89e-143	-	-	-	S	-	-	-	Cell surface protein
HFEONIEA_02035	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFEONIEA_02036	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFEONIEA_02037	5.56e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HFEONIEA_02038	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFEONIEA_02039	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFEONIEA_02040	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFEONIEA_02041	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFEONIEA_02042	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HFEONIEA_02043	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFEONIEA_02044	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFEONIEA_02045	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFEONIEA_02046	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFEONIEA_02047	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFEONIEA_02048	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFEONIEA_02049	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFEONIEA_02050	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFEONIEA_02051	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFEONIEA_02052	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_02053	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFEONIEA_02054	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFEONIEA_02056	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFEONIEA_02057	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFEONIEA_02058	6.37e-280	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFEONIEA_02059	5.78e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HFEONIEA_02060	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFEONIEA_02061	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFEONIEA_02062	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFEONIEA_02064	1.39e-182	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFEONIEA_02065	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HFEONIEA_02066	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HFEONIEA_02067	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HFEONIEA_02068	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HFEONIEA_02069	2.54e-50	-	-	-	-	-	-	-	-
HFEONIEA_02070	1.72e-291	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFEONIEA_02073	3.27e-12	-	-	-	-	-	-	-	-
HFEONIEA_02074	3.91e-37	-	-	-	-	-	-	-	-
HFEONIEA_02075	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HFEONIEA_02076	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFEONIEA_02077	4.22e-215	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HFEONIEA_02078	6.91e-234	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HFEONIEA_02079	1.23e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HFEONIEA_02080	4.75e-305	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HFEONIEA_02081	9.89e-199	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HFEONIEA_02082	6.82e-224	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFEONIEA_02083	6.35e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFEONIEA_02084	1.71e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HFEONIEA_02085	7.32e-46	-	-	-	-	-	-	-	-
HFEONIEA_02088	4.06e-126	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HFEONIEA_02092	1.28e-78	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HFEONIEA_02093	2.05e-38	-	-	-	D	-	-	-	nuclear chromosome segregation
HFEONIEA_02095	8.06e-51	-	-	-	L	-	-	-	Initiator Replication protein
HFEONIEA_02096	1.68e-78	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
HFEONIEA_02097	3.96e-54	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Psort location Cytoplasmic, score 8.96
HFEONIEA_02098	7.36e-113	dcm	-	-	H	-	-	-	Adenine-specific methyltransferase EcoRI
HFEONIEA_02099	8.96e-130	-	-	-	-	-	-	-	-
HFEONIEA_02100	1.46e-21	-	-	-	-	-	-	-	-
HFEONIEA_02102	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HFEONIEA_02103	1.34e-82	icaB	-	-	G	ko:K21478	-	ko00000,ko01000	deacetylase
HFEONIEA_02105	1.84e-125	icaA	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
HFEONIEA_02106	7.79e-11	-	-	-	M	-	-	-	domain protein
HFEONIEA_02107	1.02e-73	-	-	-	-	-	-	-	-
HFEONIEA_02108	3.55e-146	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HFEONIEA_02109	6.08e-97	-	-	-	L	-	-	-	Transposase DDE domain
HFEONIEA_02110	1.35e-71	-	-	-	-	-	-	-	-
HFEONIEA_02111	1.34e-86	-	-	-	-	-	-	-	-
HFEONIEA_02113	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFEONIEA_02114	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HFEONIEA_02115	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFEONIEA_02116	7.81e-46	-	-	-	-	-	-	-	-
HFEONIEA_02117	1.92e-161	-	-	-	P	-	-	-	integral membrane protein, YkoY family
HFEONIEA_02119	2.37e-49	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HFEONIEA_02120	5.5e-314	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFEONIEA_02121	2.23e-74	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFEONIEA_02122	4.52e-71	-	-	-	L	-	-	-	Phage integrase family
HFEONIEA_02123	7.81e-37	-	-	-	-	-	-	-	-
HFEONIEA_02124	1.28e-69	-	-	-	-	-	-	-	-
HFEONIEA_02125	1.72e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFEONIEA_02126	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HFEONIEA_02127	8.86e-35	-	-	-	-	-	-	-	-
HFEONIEA_02128	6.47e-10	-	-	-	P	-	-	-	Cation efflux family
HFEONIEA_02129	1.62e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFEONIEA_02130	5.38e-75	-	-	-	-	-	-	-	-
HFEONIEA_02131	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFEONIEA_02132	5.24e-53	-	-	-	-	-	-	-	-
HFEONIEA_02134	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFEONIEA_02135	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFEONIEA_02136	1.02e-312	yycH	-	-	S	-	-	-	YycH protein
HFEONIEA_02137	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HFEONIEA_02138	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HFEONIEA_02139	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HFEONIEA_02140	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFEONIEA_02141	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_02142	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HFEONIEA_02143	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HFEONIEA_02144	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
HFEONIEA_02145	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HFEONIEA_02146	5.25e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HFEONIEA_02147	0.0	-	-	-	C	-	-	-	FMN_bind
HFEONIEA_02148	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFEONIEA_02149	1.46e-204	-	-	-	K	-	-	-	LysR family
HFEONIEA_02150	2.49e-95	-	-	-	C	-	-	-	FMN binding
HFEONIEA_02151	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFEONIEA_02152	4.06e-211	-	-	-	S	-	-	-	KR domain
HFEONIEA_02153	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HFEONIEA_02154	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HFEONIEA_02155	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HFEONIEA_02156	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HFEONIEA_02157	1.8e-247	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFEONIEA_02158	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFEONIEA_02159	3.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFEONIEA_02160	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HFEONIEA_02161	1.65e-106	-	-	-	S	-	-	-	ASCH
HFEONIEA_02162	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HFEONIEA_02163	1.67e-220	-	-	-	K	-	-	-	WYL domain
HFEONIEA_02164	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFEONIEA_02165	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HFEONIEA_02166	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HFEONIEA_02167	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
HFEONIEA_02168	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HFEONIEA_02169	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HFEONIEA_02170	1.63e-161	-	-	-	S	-	-	-	DJ-1/PfpI family
HFEONIEA_02171	1.28e-229	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HFEONIEA_02172	1.69e-62	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_02173	1.71e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HFEONIEA_02174	3.36e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFEONIEA_02175	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HFEONIEA_02176	2.38e-99	-	-	-	-	-	-	-	-
HFEONIEA_02177	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HFEONIEA_02178	3.42e-180	-	-	-	-	-	-	-	-
HFEONIEA_02179	4.07e-05	-	-	-	-	-	-	-	-
HFEONIEA_02180	4.46e-181	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HFEONIEA_02181	1.67e-54	-	-	-	-	-	-	-	-
HFEONIEA_02182	3.52e-165	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_02183	5.66e-191	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFEONIEA_02184	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HFEONIEA_02185	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HFEONIEA_02186	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HFEONIEA_02187	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HFEONIEA_02188	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HFEONIEA_02189	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HFEONIEA_02190	2.8e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFEONIEA_02191	1.29e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HFEONIEA_02192	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFEONIEA_02193	3.77e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFEONIEA_02194	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFEONIEA_02195	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFEONIEA_02196	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HFEONIEA_02197	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HFEONIEA_02198	0.0	-	-	-	L	-	-	-	HIRAN domain
HFEONIEA_02199	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HFEONIEA_02200	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HFEONIEA_02201	5.15e-187	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HFEONIEA_02202	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HFEONIEA_02203	2.48e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFEONIEA_02204	2.81e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFEONIEA_02205	2.44e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HFEONIEA_02206	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFEONIEA_02207	8.08e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
HFEONIEA_02208	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HFEONIEA_02209	3.61e-144	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HFEONIEA_02210	9.35e-101	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02211	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFEONIEA_02212	4.54e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HFEONIEA_02213	4.46e-88	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFEONIEA_02214	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HFEONIEA_02215	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_02216	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HFEONIEA_02218	2.16e-204	morA	-	-	S	-	-	-	reductase
HFEONIEA_02219	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HFEONIEA_02220	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HFEONIEA_02221	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HFEONIEA_02222	6.97e-126	-	-	-	-	-	-	-	-
HFEONIEA_02223	0.0	-	-	-	-	-	-	-	-
HFEONIEA_02224	1.63e-222	-	-	-	C	-	-	-	Oxidoreductase
HFEONIEA_02225	4.46e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HFEONIEA_02226	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02227	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HFEONIEA_02229	3.08e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HFEONIEA_02230	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HFEONIEA_02231	3.14e-182	-	-	-	-	-	-	-	-
HFEONIEA_02232	3.16e-191	-	-	-	-	-	-	-	-
HFEONIEA_02233	3.37e-115	-	-	-	-	-	-	-	-
HFEONIEA_02234	2.05e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HFEONIEA_02235	4.07e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_02236	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HFEONIEA_02237	1.14e-150	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_02238	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HFEONIEA_02239	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HFEONIEA_02241	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_02242	2.74e-242	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HFEONIEA_02243	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HFEONIEA_02244	3.9e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HFEONIEA_02245	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HFEONIEA_02246	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFEONIEA_02247	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFEONIEA_02248	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HFEONIEA_02249	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HFEONIEA_02250	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFEONIEA_02251	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFEONIEA_02252	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_02253	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HFEONIEA_02254	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HFEONIEA_02255	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFEONIEA_02256	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFEONIEA_02257	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HFEONIEA_02258	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HFEONIEA_02259	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFEONIEA_02260	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HFEONIEA_02261	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_02262	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HFEONIEA_02263	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFEONIEA_02264	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFEONIEA_02265	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HFEONIEA_02266	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFEONIEA_02267	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFEONIEA_02268	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_02269	0.0	-	-	-	M	-	-	-	domain protein
HFEONIEA_02271	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFEONIEA_02272	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFEONIEA_02273	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFEONIEA_02274	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HFEONIEA_02275	1.69e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFEONIEA_02276	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFEONIEA_02277	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HFEONIEA_02278	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HFEONIEA_02279	6.33e-46	-	-	-	-	-	-	-	-
HFEONIEA_02280	4.69e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HFEONIEA_02281	1.46e-206	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HFEONIEA_02282	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFEONIEA_02283	3.81e-18	-	-	-	-	-	-	-	-
HFEONIEA_02284	5.08e-74	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFEONIEA_02285	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFEONIEA_02286	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HFEONIEA_02287	2.13e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HFEONIEA_02288	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFEONIEA_02289	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HFEONIEA_02290	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HFEONIEA_02291	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HFEONIEA_02292	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFEONIEA_02293	4.02e-90	-	-	-	-	-	-	-	-
HFEONIEA_02294	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HFEONIEA_02295	1.29e-169	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFEONIEA_02296	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HFEONIEA_02297	4.55e-282	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HFEONIEA_02298	2.46e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HFEONIEA_02299	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFEONIEA_02300	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFEONIEA_02301	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HFEONIEA_02302	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_02303	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HFEONIEA_02304	2.43e-111	-	-	-	-	-	-	-	-
HFEONIEA_02305	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFEONIEA_02306	7.19e-68	-	-	-	-	-	-	-	-
HFEONIEA_02307	1.22e-125	-	-	-	-	-	-	-	-
HFEONIEA_02308	2.98e-90	-	-	-	-	-	-	-	-
HFEONIEA_02309	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HFEONIEA_02310	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HFEONIEA_02311	3.67e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HFEONIEA_02312	2.8e-161	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HFEONIEA_02313	4.08e-291	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_02314	3.56e-52	-	-	-	-	-	-	-	-
HFEONIEA_02315	2.18e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFEONIEA_02316	6.28e-272	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HFEONIEA_02317	8.38e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HFEONIEA_02318	7.08e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HFEONIEA_02319	1.17e-244	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HFEONIEA_02320	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HFEONIEA_02321	1e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFEONIEA_02322	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFEONIEA_02323	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HFEONIEA_02324	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HFEONIEA_02325	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HFEONIEA_02326	2.21e-56	-	-	-	-	-	-	-	-
HFEONIEA_02327	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HFEONIEA_02328	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFEONIEA_02329	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_02330	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFEONIEA_02331	2.6e-185	-	-	-	-	-	-	-	-
HFEONIEA_02332	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HFEONIEA_02333	4.5e-303	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HFEONIEA_02334	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFEONIEA_02335	1.3e-203	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFEONIEA_02336	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HFEONIEA_02337	4.36e-89	-	-	-	-	-	-	-	-
HFEONIEA_02338	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02339	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_02340	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFEONIEA_02341	1.15e-152	-	-	-	-	-	-	-	-
HFEONIEA_02342	2.92e-57	-	-	-	-	-	-	-	-
HFEONIEA_02343	1.55e-55	-	-	-	-	-	-	-	-
HFEONIEA_02344	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_02345	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_02346	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
HFEONIEA_02347	2.21e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HFEONIEA_02348	2.42e-65	-	-	-	-	-	-	-	-
HFEONIEA_02349	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFEONIEA_02350	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_02351	3.35e-75	-	-	-	-	-	-	-	-
HFEONIEA_02352	2.87e-56	-	-	-	-	-	-	-	-
HFEONIEA_02353	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFEONIEA_02354	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFEONIEA_02355	1.49e-63	-	-	-	-	-	-	-	-
HFEONIEA_02356	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFEONIEA_02357	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HFEONIEA_02358	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HFEONIEA_02359	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HFEONIEA_02360	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HFEONIEA_02361	1.84e-295	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HFEONIEA_02362	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_02363	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HFEONIEA_02364	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFEONIEA_02365	6.74e-261	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_02366	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HFEONIEA_02367	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_02368	1.82e-130	-	-	-	-	-	-	-	-
HFEONIEA_02369	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HFEONIEA_02370	5.9e-258	-	-	-	S	-	-	-	Phage portal protein
HFEONIEA_02371	0.000703	-	-	-	-	-	-	-	-
HFEONIEA_02372	1.91e-176	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HFEONIEA_02373	2.68e-86	-	-	-	L	-	-	-	HNH endonuclease
HFEONIEA_02374	2.89e-65	-	-	-	S	-	-	-	Head-tail joining protein
HFEONIEA_02375	3.09e-35	-	-	-	-	-	-	-	-
HFEONIEA_02376	8.99e-109	-	-	-	-	-	-	-	-
HFEONIEA_02377	1.56e-53	-	-	-	S	-	-	-	Virulence-associated protein E
HFEONIEA_02378	8.83e-06	-	-	-	-	-	-	-	-
HFEONIEA_02379	2.21e-84	-	-	-	D	-	-	-	AAA domain
HFEONIEA_02380	5.3e-49	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFEONIEA_02381	1.89e-91	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HFEONIEA_02382	1.95e-68	-	-	-	S	-	-	-	Head-tail joining protein
HFEONIEA_02383	1.13e-28	-	-	-	-	-	-	-	-
HFEONIEA_02384	3.14e-109	-	-	-	-	-	-	-	-
HFEONIEA_02385	3e-57	-	-	-	S	-	-	-	Virulence-associated protein E
HFEONIEA_02386	2.14e-199	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFEONIEA_02389	3.65e-75	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02390	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HFEONIEA_02391	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HFEONIEA_02392	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFEONIEA_02393	4.27e-89	-	-	-	-	-	-	-	-
HFEONIEA_02394	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HFEONIEA_02395	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HFEONIEA_02396	3.18e-261	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HFEONIEA_02397	3.89e-62	-	-	-	-	-	-	-	-
HFEONIEA_02398	1.57e-71	-	-	-	-	-	-	-	-
HFEONIEA_02399	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HFEONIEA_02400	4.05e-98	-	-	-	-	-	-	-	-
HFEONIEA_02401	1.69e-77	-	-	-	-	-	-	-	-
HFEONIEA_02402	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HFEONIEA_02403	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HFEONIEA_02404	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HFEONIEA_02405	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFEONIEA_02406	2.73e-24	-	-	-	-	-	-	-	-
HFEONIEA_02407	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HFEONIEA_02408	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HFEONIEA_02409	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFEONIEA_02410	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFEONIEA_02411	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HFEONIEA_02412	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFEONIEA_02413	5.14e-212	-	-	-	S	-	-	-	Putative esterase
HFEONIEA_02414	2.04e-168	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02415	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFEONIEA_02416	6.08e-179	-	-	-	-	-	-	-	-
HFEONIEA_02417	1.02e-152	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFEONIEA_02418	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HFEONIEA_02419	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFEONIEA_02420	5.4e-80	-	-	-	-	-	-	-	-
HFEONIEA_02421	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFEONIEA_02422	2.97e-76	-	-	-	-	-	-	-	-
HFEONIEA_02423	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HFEONIEA_02424	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HFEONIEA_02425	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFEONIEA_02426	1.74e-51	yttB	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_02427	7.61e-65	yttB	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_02428	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFEONIEA_02429	3.63e-219	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFEONIEA_02430	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFEONIEA_02431	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFEONIEA_02432	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HFEONIEA_02433	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFEONIEA_02434	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFEONIEA_02435	3.59e-26	-	-	-	-	-	-	-	-
HFEONIEA_02436	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFEONIEA_02437	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HFEONIEA_02438	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HFEONIEA_02439	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFEONIEA_02440	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFEONIEA_02441	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFEONIEA_02442	1.34e-218	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HFEONIEA_02443	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFEONIEA_02444	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFEONIEA_02445	2.99e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFEONIEA_02446	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFEONIEA_02447	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFEONIEA_02448	1.38e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFEONIEA_02449	3.5e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFEONIEA_02450	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFEONIEA_02451	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HFEONIEA_02452	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HFEONIEA_02453	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HFEONIEA_02454	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
HFEONIEA_02455	1.25e-199	-	-	-	T	-	-	-	EAL domain
HFEONIEA_02456	4.23e-84	-	-	-	-	-	-	-	-
HFEONIEA_02457	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HFEONIEA_02458	3.16e-158	-	-	-	E	-	-	-	Methionine synthase
HFEONIEA_02459	3.85e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFEONIEA_02460	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFEONIEA_02461	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFEONIEA_02462	4.04e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFEONIEA_02463	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFEONIEA_02464	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFEONIEA_02465	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFEONIEA_02466	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFEONIEA_02467	3.95e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFEONIEA_02468	6.77e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFEONIEA_02469	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFEONIEA_02470	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HFEONIEA_02471	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFEONIEA_02472	1.16e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HFEONIEA_02473	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFEONIEA_02474	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HFEONIEA_02475	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_02476	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HFEONIEA_02477	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02478	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HFEONIEA_02479	4.76e-56	-	-	-	-	-	-	-	-
HFEONIEA_02480	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HFEONIEA_02481	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02482	3.41e-190	-	-	-	-	-	-	-	-
HFEONIEA_02483	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HFEONIEA_02484	1.08e-47	-	-	-	-	-	-	-	-
HFEONIEA_02485	4.69e-94	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFEONIEA_02486	1.02e-113	-	-	-	-	-	-	-	-
HFEONIEA_02487	1.98e-65	-	-	-	-	-	-	-	-
HFEONIEA_02488	4.79e-13	-	-	-	-	-	-	-	-
HFEONIEA_02489	2.49e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFEONIEA_02490	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HFEONIEA_02491	1.52e-151	-	-	-	-	-	-	-	-
HFEONIEA_02492	1.21e-69	-	-	-	-	-	-	-	-
HFEONIEA_02494	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFEONIEA_02495	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HFEONIEA_02496	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFEONIEA_02497	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HFEONIEA_02498	2.05e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFEONIEA_02499	2.28e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HFEONIEA_02500	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HFEONIEA_02501	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HFEONIEA_02502	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HFEONIEA_02503	7.75e-125	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFEONIEA_02504	1.49e-120	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFEONIEA_02505	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HFEONIEA_02506	5.78e-288	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HFEONIEA_02507	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HFEONIEA_02508	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFEONIEA_02509	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02510	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_02511	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFEONIEA_02512	1.91e-316	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HFEONIEA_02513	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_02514	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_02515	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HFEONIEA_02516	1.31e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFEONIEA_02517	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HFEONIEA_02518	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HFEONIEA_02519	7.15e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HFEONIEA_02520	4.41e-106	-	-	-	-	-	-	-	-
HFEONIEA_02521	5.06e-196	-	-	-	S	-	-	-	hydrolase
HFEONIEA_02522	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFEONIEA_02523	2.3e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HFEONIEA_02524	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFEONIEA_02525	5.15e-130	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HFEONIEA_02526	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HFEONIEA_02527	2.35e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFEONIEA_02528	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HFEONIEA_02529	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HFEONIEA_02530	4.3e-44	-	-	-	-	-	-	-	-
HFEONIEA_02531	2.1e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HFEONIEA_02532	0.0	ycaM	-	-	E	-	-	-	amino acid
HFEONIEA_02533	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFEONIEA_02534	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HFEONIEA_02535	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFEONIEA_02536	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02538	2.16e-92	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFEONIEA_02540	2.36e-26	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_02541	5.17e-91	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFEONIEA_02542	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFEONIEA_02543	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFEONIEA_02544	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFEONIEA_02545	0.0	ydaO	-	-	E	-	-	-	amino acid
HFEONIEA_02546	1.04e-246	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HFEONIEA_02547	7.67e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFEONIEA_02548	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HFEONIEA_02549	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HFEONIEA_02550	9.83e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HFEONIEA_02551	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFEONIEA_02552	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFEONIEA_02553	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFEONIEA_02554	1.5e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HFEONIEA_02555	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFEONIEA_02556	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFEONIEA_02557	1.19e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFEONIEA_02558	5.23e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFEONIEA_02559	2.05e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HFEONIEA_02560	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFEONIEA_02561	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFEONIEA_02562	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HFEONIEA_02563	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HFEONIEA_02564	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HFEONIEA_02565	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFEONIEA_02566	1.47e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFEONIEA_02567	1.15e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFEONIEA_02568	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFEONIEA_02569	2.13e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFEONIEA_02570	0.0	nox	-	-	C	-	-	-	NADH oxidase
HFEONIEA_02571	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFEONIEA_02572	5.03e-140	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFEONIEA_02573	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HFEONIEA_02574	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFEONIEA_02575	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFEONIEA_02576	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFEONIEA_02577	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HFEONIEA_02578	4.38e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HFEONIEA_02579	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HFEONIEA_02580	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFEONIEA_02581	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFEONIEA_02582	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFEONIEA_02583	2.15e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFEONIEA_02584	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFEONIEA_02585	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HFEONIEA_02586	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFEONIEA_02587	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFEONIEA_02588	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFEONIEA_02589	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFEONIEA_02590	6.3e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFEONIEA_02591	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFEONIEA_02593	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HFEONIEA_02594	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HFEONIEA_02595	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFEONIEA_02596	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFEONIEA_02597	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFEONIEA_02598	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFEONIEA_02599	8.46e-170	-	-	-	-	-	-	-	-
HFEONIEA_02600	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFEONIEA_02601	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFEONIEA_02602	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HFEONIEA_02603	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFEONIEA_02604	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFEONIEA_02605	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HFEONIEA_02606	6.58e-48	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HFEONIEA_02607	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_02608	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02609	5.62e-137	-	-	-	-	-	-	-	-
HFEONIEA_02610	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFEONIEA_02611	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFEONIEA_02612	1.01e-226	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HFEONIEA_02613	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HFEONIEA_02614	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_02615	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFEONIEA_02616	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFEONIEA_02617	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HFEONIEA_02618	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HFEONIEA_02619	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFEONIEA_02620	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFEONIEA_02621	6.9e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HFEONIEA_02622	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFEONIEA_02623	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HFEONIEA_02624	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFEONIEA_02625	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFEONIEA_02626	5.44e-159	-	-	-	T	-	-	-	EAL domain
HFEONIEA_02627	1.56e-187	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HFEONIEA_02628	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_02629	3.43e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFEONIEA_02630	3.38e-70	-	-	-	-	-	-	-	-
HFEONIEA_02631	2.49e-95	-	-	-	-	-	-	-	-
HFEONIEA_02632	7.06e-169	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HFEONIEA_02633	7.32e-132	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HFEONIEA_02634	1.68e-80	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HFEONIEA_02635	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFEONIEA_02636	5.03e-183	-	-	-	-	-	-	-	-
HFEONIEA_02638	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HFEONIEA_02639	3.88e-46	-	-	-	-	-	-	-	-
HFEONIEA_02640	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HFEONIEA_02641	1.76e-313	-	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_02642	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFEONIEA_02643	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFEONIEA_02644	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFEONIEA_02645	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HFEONIEA_02646	1.24e-106	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02647	1.36e-27	-	-	-	-	-	-	-	-
HFEONIEA_02648	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFEONIEA_02649	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFEONIEA_02650	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFEONIEA_02651	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFEONIEA_02652	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFEONIEA_02653	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFEONIEA_02654	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HFEONIEA_02655	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFEONIEA_02656	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HFEONIEA_02657	3.8e-61	-	-	-	-	-	-	-	-
HFEONIEA_02658	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFEONIEA_02659	5.04e-114	-	-	-	-	-	-	-	-
HFEONIEA_02660	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HFEONIEA_02661	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HFEONIEA_02662	1.48e-27	-	-	-	-	-	-	-	-
HFEONIEA_02663	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HFEONIEA_02664	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HFEONIEA_02665	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HFEONIEA_02666	8.33e-188	-	-	-	-	-	-	-	-
HFEONIEA_02668	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HFEONIEA_02669	7.9e-269	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFEONIEA_02670	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFEONIEA_02671	5.2e-54	-	-	-	-	-	-	-	-
HFEONIEA_02673	6.59e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02674	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFEONIEA_02675	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_02676	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFEONIEA_02678	4.54e-54	-	-	-	-	-	-	-	-
HFEONIEA_02680	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
HFEONIEA_02681	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFEONIEA_02682	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HFEONIEA_02683	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFEONIEA_02684	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HFEONIEA_02685	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HFEONIEA_02686	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFEONIEA_02687	3.47e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HFEONIEA_02688	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HFEONIEA_02689	9.21e-123	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HFEONIEA_02690	8.03e-28	-	-	-	-	-	-	-	-
HFEONIEA_02692	1.82e-130	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFEONIEA_02693	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HFEONIEA_02694	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HFEONIEA_02695	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HFEONIEA_02696	2.8e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HFEONIEA_02697	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HFEONIEA_02698	5.85e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HFEONIEA_02699	4.41e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFEONIEA_02700	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFEONIEA_02701	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFEONIEA_02703	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HFEONIEA_02704	7.97e-108	-	-	-	-	-	-	-	-
HFEONIEA_02705	2.45e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFEONIEA_02706	1.12e-186	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HFEONIEA_02707	1.18e-82	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_02709	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFEONIEA_02710	2.5e-188	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFEONIEA_02711	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFEONIEA_02712	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFEONIEA_02713	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFEONIEA_02714	4.84e-71	-	-	-	S	-	-	-	Enterocin A Immunity
HFEONIEA_02715	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFEONIEA_02716	3.51e-252	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFEONIEA_02717	5.47e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFEONIEA_02718	3.33e-209	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HFEONIEA_02719	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HFEONIEA_02720	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HFEONIEA_02721	1.03e-34	-	-	-	-	-	-	-	-
HFEONIEA_02722	1.56e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HFEONIEA_02723	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HFEONIEA_02724	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HFEONIEA_02725	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_02726	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HFEONIEA_02727	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HFEONIEA_02728	7.43e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HFEONIEA_02729	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HFEONIEA_02730	1.16e-135	-	-	-	-	-	-	-	-
HFEONIEA_02731	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HFEONIEA_02732	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFEONIEA_02734	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HFEONIEA_02735	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_02736	1.43e-44	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_02737	2.16e-199	-	-	-	GM	-	-	-	NmrA-like family
HFEONIEA_02738	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HFEONIEA_02739	5.86e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFEONIEA_02740	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HFEONIEA_02741	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFEONIEA_02742	1.35e-154	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HFEONIEA_02743	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HFEONIEA_02744	3e-114	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFEONIEA_02745	3.03e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFEONIEA_02746	7.72e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HFEONIEA_02747	6.26e-101	-	-	-	-	-	-	-	-
HFEONIEA_02748	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFEONIEA_02749	5.06e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02750	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HFEONIEA_02751	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HFEONIEA_02752	6.39e-234	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HFEONIEA_02753	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFEONIEA_02754	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFEONIEA_02755	9.68e-202	-	-	-	S	-	-	-	Putative adhesin
HFEONIEA_02756	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HFEONIEA_02757	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HFEONIEA_02758	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
HFEONIEA_02759	3.6e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFEONIEA_02760	1.74e-175	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02761	8.59e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFEONIEA_02762	6.12e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFEONIEA_02763	1.19e-297	-	-	-	EK	-	-	-	Aminotransferase, class I
HFEONIEA_02764	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HFEONIEA_02765	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_02766	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFEONIEA_02767	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HFEONIEA_02768	4.27e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HFEONIEA_02769	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFEONIEA_02770	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HFEONIEA_02771	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFEONIEA_02772	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HFEONIEA_02773	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFEONIEA_02774	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HFEONIEA_02775	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFEONIEA_02776	1.91e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFEONIEA_02777	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HFEONIEA_02778	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HFEONIEA_02779	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HFEONIEA_02780	2.96e-302	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFEONIEA_02781	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HFEONIEA_02782	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HFEONIEA_02783	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HFEONIEA_02784	9.65e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFEONIEA_02785	5.01e-71	-	-	-	-	-	-	-	-
HFEONIEA_02787	2.29e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFEONIEA_02788	1.01e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HFEONIEA_02789	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HFEONIEA_02790	3.08e-255	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HFEONIEA_02791	2e-211	-	-	-	-	-	-	-	-
HFEONIEA_02792	4.45e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFEONIEA_02793	5.21e-151	-	-	-	-	-	-	-	-
HFEONIEA_02794	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HFEONIEA_02795	3.23e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFEONIEA_02796	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFEONIEA_02797	1.94e-153	-	-	-	Q	-	-	-	Methyltransferase domain
HFEONIEA_02798	5.02e-52	-	-	-	-	-	-	-	-
HFEONIEA_02799	1.11e-81	-	-	-	S	-	-	-	PFAM Metallo-beta-lactamase superfamily
HFEONIEA_02800	6.11e-09	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
HFEONIEA_02801	1.67e-148	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HFEONIEA_02802	5.82e-46	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFEONIEA_02803	6.52e-69	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HFEONIEA_02804	8.34e-65	-	-	-	-	-	-	-	-
HFEONIEA_02805	5.03e-75	-	-	-	-	-	-	-	-
HFEONIEA_02807	7.58e-210	-	-	-	-	-	-	-	-
HFEONIEA_02808	3.3e-94	-	-	-	K	-	-	-	Transcriptional regulator
HFEONIEA_02809	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HFEONIEA_02810	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFEONIEA_02811	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HFEONIEA_02812	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HFEONIEA_02813	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_02814	2.66e-172	-	-	-	-	-	-	-	-
HFEONIEA_02815	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HFEONIEA_02816	2.57e-77	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFEONIEA_02817	5.59e-308	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFEONIEA_02818	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFEONIEA_02819	2.11e-251	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HFEONIEA_02820	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HFEONIEA_02821	5.91e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFEONIEA_02822	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HFEONIEA_02823	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFEONIEA_02824	7.74e-205	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFEONIEA_02825	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HFEONIEA_02826	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HFEONIEA_02827	2.46e-216	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HFEONIEA_02828	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_02829	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFEONIEA_02830	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HFEONIEA_02831	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFEONIEA_02832	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFEONIEA_02833	2.99e-50	-	-	-	M	-	-	-	domain protein
HFEONIEA_02834	1.98e-309	-	-	-	M	-	-	-	domain protein
HFEONIEA_02835	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HFEONIEA_02836	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFEONIEA_02837	1.45e-46	-	-	-	-	-	-	-	-
HFEONIEA_02838	3.17e-235	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFEONIEA_02839	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFEONIEA_02840	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HFEONIEA_02841	1.44e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFEONIEA_02842	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HFEONIEA_02843	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HFEONIEA_02844	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFEONIEA_02845	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HFEONIEA_02846	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HFEONIEA_02847	1.27e-272	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFEONIEA_02848	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFEONIEA_02849	3.17e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFEONIEA_02850	7.04e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HFEONIEA_02851	4.5e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFEONIEA_02852	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFEONIEA_02853	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFEONIEA_02854	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFEONIEA_02855	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HFEONIEA_02856	3.68e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFEONIEA_02857	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFEONIEA_02858	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HFEONIEA_02859	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HFEONIEA_02860	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HFEONIEA_02861	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02862	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFEONIEA_02863	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFEONIEA_02864	2.55e-212	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFEONIEA_02865	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HFEONIEA_02866	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HFEONIEA_02867	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFEONIEA_02868	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFEONIEA_02869	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFEONIEA_02870	2.76e-43	-	-	-	-	-	-	-	-
HFEONIEA_02871	9.95e-108	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFEONIEA_02872	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFEONIEA_02873	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFEONIEA_02874	2.69e-276	-	-	-	T	-	-	-	diguanylate cyclase
HFEONIEA_02875	1.11e-45	-	-	-	-	-	-	-	-
HFEONIEA_02876	2.29e-48	-	-	-	-	-	-	-	-
HFEONIEA_02877	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HFEONIEA_02878	1.37e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HFEONIEA_02879	1.65e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFEONIEA_02881	2.68e-32	-	-	-	-	-	-	-	-
HFEONIEA_02882	5.44e-176	-	-	-	F	-	-	-	NUDIX domain
HFEONIEA_02883	1.96e-273	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HFEONIEA_02884	1.31e-64	-	-	-	-	-	-	-	-
HFEONIEA_02885	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HFEONIEA_02887	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HFEONIEA_02888	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HFEONIEA_02889	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HFEONIEA_02890	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HFEONIEA_02891	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HFEONIEA_02892	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HFEONIEA_02893	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFEONIEA_02894	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFEONIEA_02895	2.1e-33	-	-	-	-	-	-	-	-
HFEONIEA_02896	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFEONIEA_02897	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFEONIEA_02898	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HFEONIEA_02899	4.63e-24	-	-	-	-	-	-	-	-
HFEONIEA_02900	2.16e-26	-	-	-	-	-	-	-	-
HFEONIEA_02901	1.56e-22	-	-	-	-	-	-	-	-
HFEONIEA_02902	3.26e-24	-	-	-	-	-	-	-	-
HFEONIEA_02903	6.58e-24	-	-	-	-	-	-	-	-
HFEONIEA_02905	5.16e-107	inlJ	-	-	M	-	-	-	MucBP domain
HFEONIEA_02906	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HFEONIEA_02907	1.27e-109	-	-	-	K	-	-	-	MarR family
HFEONIEA_02908	9.28e-58	-	-	-	-	-	-	-	-
HFEONIEA_02909	1.28e-51	-	-	-	-	-	-	-	-
HFEONIEA_02910	2.33e-285	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFEONIEA_02913	8e-13	-	-	-	-	-	-	-	-
HFEONIEA_02914	3.6e-42	-	-	-	-	-	-	-	-
HFEONIEA_02917	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFEONIEA_02918	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFEONIEA_02919	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFEONIEA_02920	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFEONIEA_02921	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFEONIEA_02922	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFEONIEA_02923	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HFEONIEA_02924	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFEONIEA_02926	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HFEONIEA_02927	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFEONIEA_02928	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFEONIEA_02929	8.29e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFEONIEA_02930	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFEONIEA_02931	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFEONIEA_02932	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HFEONIEA_02933	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HFEONIEA_02934	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFEONIEA_02935	5.21e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HFEONIEA_02936	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HFEONIEA_02937	9.73e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFEONIEA_02938	1.79e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFEONIEA_02939	1.06e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFEONIEA_02940	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFEONIEA_02941	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFEONIEA_02942	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFEONIEA_02943	7.93e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HFEONIEA_02944	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFEONIEA_02945	4.28e-84	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HFEONIEA_02946	1.43e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFEONIEA_02947	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFEONIEA_02948	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFEONIEA_02949	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFEONIEA_02950	1.84e-189	-	-	-	-	-	-	-	-
HFEONIEA_02951	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFEONIEA_02952	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HFEONIEA_02953	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HFEONIEA_02954	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HFEONIEA_02955	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFEONIEA_02956	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFEONIEA_02957	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFEONIEA_02958	2.41e-37	-	-	-	-	-	-	-	-
HFEONIEA_02959	2.3e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HFEONIEA_02960	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFEONIEA_02961	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HFEONIEA_02962	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HFEONIEA_02963	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFEONIEA_02964	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFEONIEA_02965	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFEONIEA_02966	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HFEONIEA_02967	2.68e-201	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HFEONIEA_02968	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HFEONIEA_02969	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HFEONIEA_02970	2.89e-177	-	-	-	-	-	-	-	-
HFEONIEA_02971	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
HFEONIEA_02972	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFEONIEA_02973	2.82e-196	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HFEONIEA_02974	1.34e-297	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFEONIEA_02975	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFEONIEA_02976	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HFEONIEA_02977	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFEONIEA_02978	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HFEONIEA_02979	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFEONIEA_02980	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HFEONIEA_02981	5.89e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFEONIEA_02982	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFEONIEA_02983	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HFEONIEA_02984	2.36e-269	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HFEONIEA_02985	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFEONIEA_02986	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HFEONIEA_02987	3.74e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HFEONIEA_02988	1.24e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HFEONIEA_02989	1.82e-226	-	-	-	-	-	-	-	-
HFEONIEA_02990	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HFEONIEA_02991	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFEONIEA_02992	1.4e-242	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFEONIEA_02993	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFEONIEA_02994	6.97e-209	-	-	-	GK	-	-	-	ROK family
HFEONIEA_02995	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFEONIEA_02996	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_02997	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HFEONIEA_02998	9.68e-34	-	-	-	-	-	-	-	-
HFEONIEA_02999	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFEONIEA_03000	2.21e-165	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HFEONIEA_03001	1.36e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFEONIEA_03002	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HFEONIEA_03003	0.0	-	-	-	L	-	-	-	DNA helicase
HFEONIEA_03004	5.5e-42	-	-	-	-	-	-	-	-