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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MHGEFPCD_00001	5.59e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHGEFPCD_00002	1.4e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHGEFPCD_00003	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MHGEFPCD_00004	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHGEFPCD_00005	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MHGEFPCD_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHGEFPCD_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHGEFPCD_00008	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00011	2.46e-235	yaaC	-	-	S	-	-	-	YaaC-like Protein
MHGEFPCD_00012	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHGEFPCD_00013	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHGEFPCD_00014	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHGEFPCD_00015	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHGEFPCD_00016	3.2e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHGEFPCD_00017	1.46e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MHGEFPCD_00019	7.51e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MHGEFPCD_00020	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MHGEFPCD_00021	7.12e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MHGEFPCD_00022	1.44e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MHGEFPCD_00023	2.48e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHGEFPCD_00024	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHGEFPCD_00025	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHGEFPCD_00026	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHGEFPCD_00027	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MHGEFPCD_00028	1.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MHGEFPCD_00029	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00032	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MHGEFPCD_00033	2.51e-137	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHGEFPCD_00034	5.7e-243	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MHGEFPCD_00035	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MHGEFPCD_00036	5.46e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHGEFPCD_00037	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00038	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MHGEFPCD_00039	2.32e-234	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MHGEFPCD_00040	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MHGEFPCD_00041	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MHGEFPCD_00042	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MHGEFPCD_00043	4.03e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MHGEFPCD_00044	1.93e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHGEFPCD_00045	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MHGEFPCD_00046	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHGEFPCD_00047	3.54e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MHGEFPCD_00048	2.38e-308	yabE	-	-	T	-	-	-	protein conserved in bacteria
MHGEFPCD_00049	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHGEFPCD_00050	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHGEFPCD_00051	1.16e-208	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MHGEFPCD_00052	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00053	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MHGEFPCD_00054	2.73e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHGEFPCD_00055	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MHGEFPCD_00056	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MHGEFPCD_00057	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHGEFPCD_00058	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHGEFPCD_00059	2.47e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHGEFPCD_00060	6.18e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHGEFPCD_00061	1.95e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHGEFPCD_00062	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MHGEFPCD_00063	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHGEFPCD_00064	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MHGEFPCD_00065	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHGEFPCD_00066	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHGEFPCD_00067	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHGEFPCD_00068	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MHGEFPCD_00069	3.23e-132	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MHGEFPCD_00070	1.7e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MHGEFPCD_00071	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MHGEFPCD_00074	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MHGEFPCD_00075	3.79e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MHGEFPCD_00076	2.32e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MHGEFPCD_00077	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHGEFPCD_00078	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MHGEFPCD_00079	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHGEFPCD_00080	8.14e-178	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHGEFPCD_00081	3.19e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHGEFPCD_00082	2.39e-199	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MHGEFPCD_00083	8.88e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MHGEFPCD_00084	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHGEFPCD_00085	5.35e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MHGEFPCD_00086	2.33e-205	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MHGEFPCD_00087	5.07e-200	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHGEFPCD_00088	4.62e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHGEFPCD_00089	1.66e-117	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHGEFPCD_00090	6.1e-40	yazB	-	-	K	-	-	-	transcriptional
MHGEFPCD_00091	2.17e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHGEFPCD_00092	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MHGEFPCD_00093	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00103	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00104	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MHGEFPCD_00105	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MHGEFPCD_00106	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHGEFPCD_00107	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MHGEFPCD_00108	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHGEFPCD_00109	8.93e-250	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MHGEFPCD_00110	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MHGEFPCD_00111	1.18e-158	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHGEFPCD_00112	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHGEFPCD_00113	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHGEFPCD_00114	7.76e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MHGEFPCD_00115	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHGEFPCD_00116	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHGEFPCD_00117	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHGEFPCD_00118	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MHGEFPCD_00119	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MHGEFPCD_00120	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHGEFPCD_00121	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MHGEFPCD_00122	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHGEFPCD_00123	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHGEFPCD_00124	2.33e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHGEFPCD_00125	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHGEFPCD_00126	6.96e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MHGEFPCD_00127	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHGEFPCD_00128	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHGEFPCD_00129	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MHGEFPCD_00130	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHGEFPCD_00131	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHGEFPCD_00132	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHGEFPCD_00133	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHGEFPCD_00134	5.5e-238	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MHGEFPCD_00135	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MHGEFPCD_00136	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHGEFPCD_00137	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MHGEFPCD_00138	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHGEFPCD_00139	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHGEFPCD_00140	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHGEFPCD_00141	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHGEFPCD_00142	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHGEFPCD_00143	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHGEFPCD_00144	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MHGEFPCD_00145	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHGEFPCD_00146	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHGEFPCD_00147	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHGEFPCD_00148	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHGEFPCD_00149	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHGEFPCD_00150	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHGEFPCD_00151	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHGEFPCD_00152	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHGEFPCD_00153	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHGEFPCD_00154	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MHGEFPCD_00155	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MHGEFPCD_00156	7.75e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHGEFPCD_00157	4.34e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHGEFPCD_00158	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MHGEFPCD_00159	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHGEFPCD_00160	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MHGEFPCD_00161	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHGEFPCD_00162	2.28e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHGEFPCD_00163	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHGEFPCD_00164	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MHGEFPCD_00165	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHGEFPCD_00166	8.49e-191	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHGEFPCD_00167	6.51e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHGEFPCD_00168	1.02e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHGEFPCD_00169	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHGEFPCD_00170	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MHGEFPCD_00171	4.15e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MHGEFPCD_00172	9.03e-108	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MHGEFPCD_00173	3.22e-103	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MHGEFPCD_00174	1.15e-172	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MHGEFPCD_00175	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHGEFPCD_00176	3.93e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
MHGEFPCD_00177	5.1e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MHGEFPCD_00178	2.6e-182	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MHGEFPCD_00179	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00185	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00186	1.5e-277	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MHGEFPCD_00187	1.27e-313	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHGEFPCD_00188	1.34e-231	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
MHGEFPCD_00189	6.88e-257	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MHGEFPCD_00190	9.57e-289	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MHGEFPCD_00191	7.62e-223	ybaS	-	-	S	-	-	-	Na -dependent transporter
MHGEFPCD_00192	2.34e-144	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MHGEFPCD_00193	2.37e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_00194	8.92e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_00195	2.1e-220	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MHGEFPCD_00196	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MHGEFPCD_00197	5.49e-301	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00198	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MHGEFPCD_00199	1.13e-311	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MHGEFPCD_00200	8.33e-310	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_00201	2.83e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHGEFPCD_00202	1.56e-107	ybbJ	-	-	J	-	-	-	acetyltransferase
MHGEFPCD_00203	1.11e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MHGEFPCD_00209	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_00210	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHGEFPCD_00211	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHGEFPCD_00212	2.88e-297	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00213	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHGEFPCD_00214	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHGEFPCD_00215	1.18e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHGEFPCD_00216	3.24e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
MHGEFPCD_00217	1.89e-123	ybdN	-	-	-	-	-	-	-
MHGEFPCD_00218	5.83e-166	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MHGEFPCD_00219	1.21e-205	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
MHGEFPCD_00220	4.26e-135	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MHGEFPCD_00221	1.41e-67	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MHGEFPCD_00222	3.95e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_00224	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHGEFPCD_00225	2.64e-119	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHGEFPCD_00226	1.5e-256	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
MHGEFPCD_00227	6.83e-140	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MHGEFPCD_00228	2.17e-214	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MHGEFPCD_00229	1.65e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MHGEFPCD_00230	1.79e-250	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MHGEFPCD_00231	2.34e-35	-	-	-	-	-	-	-	-
MHGEFPCD_00232	8.99e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
MHGEFPCD_00233	2.91e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MHGEFPCD_00234	7.2e-144	yqeB	-	-	-	-	-	-	-
MHGEFPCD_00235	7.84e-55	ybyB	-	-	-	-	-	-	-
MHGEFPCD_00236	0.0	ybeC	-	-	E	-	-	-	amino acid
MHGEFPCD_00239	8.36e-54	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHGEFPCD_00241	5.14e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MHGEFPCD_00242	4.23e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MHGEFPCD_00243	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MHGEFPCD_00244	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MHGEFPCD_00245	2.02e-267	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MHGEFPCD_00247	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MHGEFPCD_00248	2.99e-46	-	-	-	-	-	-	-	-
MHGEFPCD_00249	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHGEFPCD_00250	3.68e-256	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MHGEFPCD_00251	1.08e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHGEFPCD_00252	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHGEFPCD_00253	6.05e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MHGEFPCD_00254	1.24e-193	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MHGEFPCD_00255	4.3e-55	ybfN	-	-	-	-	-	-	-
MHGEFPCD_00256	4.74e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MHGEFPCD_00257	8.22e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHGEFPCD_00258	1.44e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MHGEFPCD_00259	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHGEFPCD_00260	4.14e-230	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MHGEFPCD_00261	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MHGEFPCD_00262	3.19e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MHGEFPCD_00263	3.61e-278	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_00264	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MHGEFPCD_00265	4.65e-158	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MHGEFPCD_00266	1.98e-34	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MHGEFPCD_00267	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MHGEFPCD_00268	1.75e-100	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MHGEFPCD_00269	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MHGEFPCD_00270	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHGEFPCD_00271	2.45e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHGEFPCD_00272	8.1e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHGEFPCD_00273	2.85e-265	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MHGEFPCD_00274	2.5e-313	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MHGEFPCD_00275	3.64e-129	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MHGEFPCD_00276	1.14e-253	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MHGEFPCD_00277	1.39e-148	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHGEFPCD_00278	6.27e-248	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MHGEFPCD_00279	1.32e-219	yccK	-	-	C	-	-	-	Aldo keto reductase
MHGEFPCD_00280	2.66e-225	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MHGEFPCD_00281	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_00282	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_00283	1.42e-118	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MHGEFPCD_00284	2.35e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MHGEFPCD_00285	8.29e-179	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MHGEFPCD_00286	2.5e-11	-	-	-	EGP	-	-	-	major facilitator superfamily MFS_1
MHGEFPCD_00287	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHGEFPCD_00288	7.35e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MHGEFPCD_00289	5.69e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHGEFPCD_00290	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHGEFPCD_00291	1.15e-235	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_00292	1.16e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MHGEFPCD_00293	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MHGEFPCD_00294	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MHGEFPCD_00295	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MHGEFPCD_00296	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MHGEFPCD_00297	1.17e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
MHGEFPCD_00298	8.65e-275	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MHGEFPCD_00299	4.46e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MHGEFPCD_00300	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MHGEFPCD_00301	5.76e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MHGEFPCD_00302	7.6e-269	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MHGEFPCD_00303	3.12e-291	ycgA	-	-	S	-	-	-	Membrane
MHGEFPCD_00304	2.55e-105	ycgB	-	-	-	-	-	-	-
MHGEFPCD_00305	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MHGEFPCD_00306	1.14e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MHGEFPCD_00307	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MHGEFPCD_00308	2.82e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_00309	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MHGEFPCD_00310	8.11e-190	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MHGEFPCD_00311	7.74e-313	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHGEFPCD_00312	9.24e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MHGEFPCD_00313	3.16e-192	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHGEFPCD_00314	7.2e-09	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MHGEFPCD_00315	1.36e-140	tmrB	-	-	S	-	-	-	AAA domain
MHGEFPCD_00316	1.29e-186	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MHGEFPCD_00317	5.79e-289	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_00318	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHGEFPCD_00319	6.92e-235	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MHGEFPCD_00320	6.15e-189	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MHGEFPCD_00321	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MHGEFPCD_00322	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHGEFPCD_00323	7.72e-312	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHGEFPCD_00324	5.81e-290	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MHGEFPCD_00325	1.58e-240	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MHGEFPCD_00326	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MHGEFPCD_00327	8.45e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MHGEFPCD_00328	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MHGEFPCD_00329	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHGEFPCD_00330	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MHGEFPCD_00331	9.13e-282	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MHGEFPCD_00332	7.05e-290	yciC	-	-	S	-	-	-	GTPases (G3E family)
MHGEFPCD_00333	7.48e-283	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHGEFPCD_00334	6.3e-95	yckC	-	-	S	-	-	-	membrane
MHGEFPCD_00335	3.31e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MHGEFPCD_00336	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHGEFPCD_00337	5.81e-92	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MHGEFPCD_00338	1.88e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MHGEFPCD_00339	8.93e-124	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MHGEFPCD_00340	5.21e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MHGEFPCD_00341	4.1e-84	hxlR	-	-	K	-	-	-	transcriptional
MHGEFPCD_00342	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_00343	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_00344	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MHGEFPCD_00345	2.06e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MHGEFPCD_00346	9.53e-317	-	-	-	E	-	-	-	Aminotransferase class I and II
MHGEFPCD_00347	2.51e-165	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MHGEFPCD_00348	8.56e-142	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MHGEFPCD_00349	1.13e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHGEFPCD_00350	3.03e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MHGEFPCD_00351	2.8e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MHGEFPCD_00352	8.12e-204	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MHGEFPCD_00353	1.4e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHGEFPCD_00354	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MHGEFPCD_00355	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MHGEFPCD_00356	1.95e-99	yclD	-	-	-	-	-	-	-
MHGEFPCD_00357	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MHGEFPCD_00358	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MHGEFPCD_00360	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MHGEFPCD_00361	4.87e-301	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MHGEFPCD_00362	2.27e-249	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MHGEFPCD_00363	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_00364	3.64e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHGEFPCD_00365	1.82e-182	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHGEFPCD_00366	1.49e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MHGEFPCD_00367	1.61e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_00368	6.87e-277	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MHGEFPCD_00369	9.28e-317	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MHGEFPCD_00370	2.21e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHGEFPCD_00371	5.09e-304	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MHGEFPCD_00372	2.6e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_00373	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MHGEFPCD_00374	2.72e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHGEFPCD_00376	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHGEFPCD_00377	7.78e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_00378	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_00379	4.63e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_00380	2.78e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MHGEFPCD_00381	7.02e-316	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MHGEFPCD_00382	3.67e-196	ycnC	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00383	1.38e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MHGEFPCD_00384	1.97e-59	ycnE	-	-	S	-	-	-	Monooxygenase
MHGEFPCD_00385	1.37e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MHGEFPCD_00386	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHGEFPCD_00387	5.11e-286	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHGEFPCD_00388	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHGEFPCD_00389	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MHGEFPCD_00390	9.78e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_00391	3.03e-129	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00392	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MHGEFPCD_00393	8.6e-138	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MHGEFPCD_00394	1.36e-72	-	-	-	-	-	-	-	-
MHGEFPCD_00395	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MHGEFPCD_00396	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MHGEFPCD_00397	1.64e-263	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MHGEFPCD_00398	2.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MHGEFPCD_00400	2.69e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MHGEFPCD_00401	2.49e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MHGEFPCD_00402	5.36e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MHGEFPCD_00403	8.08e-191	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MHGEFPCD_00404	1.34e-174	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MHGEFPCD_00405	3.45e-240	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MHGEFPCD_00406	6.6e-167	kipR	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00407	1.91e-150	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MHGEFPCD_00409	5.95e-75	yczJ	-	-	S	-	-	-	biosynthesis
MHGEFPCD_00410	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MHGEFPCD_00411	2.57e-221	ycsN	-	-	S	-	-	-	Oxidoreductase
MHGEFPCD_00412	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MHGEFPCD_00413	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MHGEFPCD_00414	8.99e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_00415	7.59e-123	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MHGEFPCD_00416	2.24e-146	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHGEFPCD_00417	3.69e-101	ydaG	-	-	S	-	-	-	general stress protein
MHGEFPCD_00418	6.24e-177	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MHGEFPCD_00419	5.59e-64	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MHGEFPCD_00420	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MHGEFPCD_00421	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHGEFPCD_00422	1.11e-245	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MHGEFPCD_00423	4.42e-188	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MHGEFPCD_00424	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MHGEFPCD_00425	9.17e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MHGEFPCD_00426	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MHGEFPCD_00427	0.0	ydaO	-	-	E	-	-	-	amino acid
MHGEFPCD_00428	1.26e-96	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MHGEFPCD_00429	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MHGEFPCD_00430	1.21e-62	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MHGEFPCD_00431	2.17e-99	-	-	-	-	-	-	-	-
MHGEFPCD_00433	1.31e-152	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MHGEFPCD_00434	2.61e-53	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MHGEFPCD_00436	3.66e-17	-	-	-	-	-	-	-	-
MHGEFPCD_00438	1.2e-112	-	-	-	-	-	-	-	-
MHGEFPCD_00439	2.14e-53	-	-	-	-	-	-	-	-
MHGEFPCD_00440	3.77e-288	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MHGEFPCD_00443	1.95e-45	ydaT	-	-	-	-	-	-	-
MHGEFPCD_00444	3.89e-96	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MHGEFPCD_00445	2.87e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MHGEFPCD_00446	9.32e-183	ydbA	-	-	P	-	-	-	EcsC protein family
MHGEFPCD_00447	2.34e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MHGEFPCD_00448	1.79e-76	ydbB	-	-	G	-	-	-	Cupin domain
MHGEFPCD_00449	1.18e-78	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MHGEFPCD_00450	4.71e-199	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MHGEFPCD_00451	3.82e-255	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MHGEFPCD_00452	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MHGEFPCD_00453	1.5e-152	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MHGEFPCD_00454	3.91e-287	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHGEFPCD_00455	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
MHGEFPCD_00456	5.59e-220	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_00457	2.44e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHGEFPCD_00458	2.29e-70	ydbL	-	-	-	-	-	-	-
MHGEFPCD_00459	1.42e-258	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MHGEFPCD_00460	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
MHGEFPCD_00461	6.58e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
MHGEFPCD_00462	9.92e-161	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHGEFPCD_00463	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
MHGEFPCD_00464	2.16e-258	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MHGEFPCD_00465	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHGEFPCD_00466	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHGEFPCD_00467	2.18e-96	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MHGEFPCD_00468	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MHGEFPCD_00469	4.21e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MHGEFPCD_00470	1.54e-75	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHGEFPCD_00471	1.57e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MHGEFPCD_00472	1.98e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHGEFPCD_00473	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHGEFPCD_00474	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MHGEFPCD_00475	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MHGEFPCD_00476	6.28e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MHGEFPCD_00477	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHGEFPCD_00478	1.25e-241	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MHGEFPCD_00479	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MHGEFPCD_00480	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHGEFPCD_00481	3.8e-179	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_00482	3.89e-139	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MHGEFPCD_00483	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MHGEFPCD_00484	1.78e-21	-	-	-	-	-	-	-	-
MHGEFPCD_00485	4.27e-76	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MHGEFPCD_00493	7.8e-124	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MHGEFPCD_00494	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
MHGEFPCD_00495	3.95e-108	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MHGEFPCD_00496	2.13e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MHGEFPCD_00497	3.46e-84	-	-	-	S	-	-	-	YjbR
MHGEFPCD_00498	3.35e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00499	1.34e-145	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MHGEFPCD_00500	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MHGEFPCD_00501	1.4e-100	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MHGEFPCD_00502	2.63e-53	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00503	4.62e-107	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MHGEFPCD_00504	2.02e-76	-	-	-	P	-	-	-	Rhodanese Homology Domain
MHGEFPCD_00505	1.59e-121	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MHGEFPCD_00506	2.27e-251	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MHGEFPCD_00507	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MHGEFPCD_00508	4e-163	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHGEFPCD_00509	1.29e-159	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MHGEFPCD_00510	7.92e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MHGEFPCD_00511	6.75e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MHGEFPCD_00512	1.45e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
MHGEFPCD_00513	5.2e-103	-	-	-	S	-	-	-	DinB superfamily
MHGEFPCD_00514	2.39e-146	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
MHGEFPCD_00515	4.08e-85	-	-	-	K	-	-	-	COG1802 Transcriptional regulators
MHGEFPCD_00516	7.37e-51	-	-	-	J	-	-	-	Endoribonuclease L-PSP
MHGEFPCD_00517	9.25e-176	-	-	-	E	ko:K03837	-	ko00000,ko02000	Serine transporter
MHGEFPCD_00518	1.23e-205	-	-	-	E	-	-	-	Peptidase dimerisation domain
MHGEFPCD_00519	1.63e-160	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MHGEFPCD_00520	1.41e-221	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHGEFPCD_00521	3.03e-297	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHGEFPCD_00522	1.6e-244	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MHGEFPCD_00523	5.35e-68	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MHGEFPCD_00526	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MHGEFPCD_00527	3.35e-217	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MHGEFPCD_00528	1.5e-254	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MHGEFPCD_00531	1.04e-08	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MHGEFPCD_00532	6.14e-73	ydeH	-	-	-	-	-	-	-
MHGEFPCD_00533	1.06e-109	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
MHGEFPCD_00534	5.15e-246	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHGEFPCD_00535	7.51e-190	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MHGEFPCD_00536	2.22e-192	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHGEFPCD_00537	1.81e-293	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MHGEFPCD_00538	5.67e-210	-	-	-	S	-	-	-	Sodium Bile acid symporter family
MHGEFPCD_00539	3.68e-257	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MHGEFPCD_00540	7.29e-87	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MHGEFPCD_00541	2.42e-282	nhaC_1	-	-	C	-	-	-	antiporter
MHGEFPCD_00542	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MHGEFPCD_00543	4.19e-146	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_00545	4.42e-236	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MHGEFPCD_00546	2.43e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00547	7.15e-200	ydeK	-	-	EG	-	-	-	-transporter
MHGEFPCD_00548	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHGEFPCD_00549	5.09e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MHGEFPCD_00550	1.64e-34	yraE	-	-	-	ko:K06440	-	ko00000	-
MHGEFPCD_00551	3.04e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHGEFPCD_00552	1.66e-84	yraF	-	-	M	-	-	-	Spore coat protein
MHGEFPCD_00553	1.71e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
MHGEFPCD_00554	3.15e-136	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHGEFPCD_00555	2.54e-94	-	-	-	GK	-	-	-	Transcriptional regulator
MHGEFPCD_00556	4.09e-31	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MHGEFPCD_00557	2.44e-275	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_00558	2.4e-143	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHGEFPCD_00559	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MHGEFPCD_00560	2.8e-170	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MHGEFPCD_00561	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MHGEFPCD_00562	1.29e-127	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHGEFPCD_00563	6.07e-192	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHGEFPCD_00564	6.59e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MHGEFPCD_00565	5.54e-268	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MHGEFPCD_00566	1.17e-289	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHGEFPCD_00567	2.24e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHGEFPCD_00568	7.39e-157	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHGEFPCD_00569	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MHGEFPCD_00570	5.9e-193	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHGEFPCD_00571	2.1e-190	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHGEFPCD_00572	3.32e-147	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MHGEFPCD_00573	1.9e-187	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MHGEFPCD_00574	5.06e-211	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
MHGEFPCD_00575	2.67e-153	ydhC	-	-	K	-	-	-	FCD
MHGEFPCD_00576	3.92e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHGEFPCD_00579	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MHGEFPCD_00581	2.49e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MHGEFPCD_00582	1.58e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MHGEFPCD_00583	4.15e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MHGEFPCD_00584	8.94e-152	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MHGEFPCD_00585	4.12e-275	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MHGEFPCD_00586	1.48e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MHGEFPCD_00587	3.69e-66	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MHGEFPCD_00588	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00589	0.0	ybeC	-	-	E	-	-	-	amino acid
MHGEFPCD_00590	4.94e-211	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MHGEFPCD_00591	5.46e-110	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MHGEFPCD_00592	1.15e-236	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MHGEFPCD_00593	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHGEFPCD_00596	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00599	6.91e-234	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MHGEFPCD_00600	5.22e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MHGEFPCD_00601	1.02e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MHGEFPCD_00602	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHGEFPCD_00603	9.22e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHGEFPCD_00604	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MHGEFPCD_00605	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHGEFPCD_00606	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHGEFPCD_00607	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHGEFPCD_00608	1.92e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHGEFPCD_00609	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MHGEFPCD_00610	8.26e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHGEFPCD_00611	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHGEFPCD_00612	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHGEFPCD_00613	7.07e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
MHGEFPCD_00615	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MHGEFPCD_00616	7.16e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MHGEFPCD_00617	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MHGEFPCD_00618	4.24e-221	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MHGEFPCD_00619	2.54e-41	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MHGEFPCD_00620	3.2e-145	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MHGEFPCD_00621	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHGEFPCD_00622	2.24e-162	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MHGEFPCD_00623	3.75e-222	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MHGEFPCD_00624	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MHGEFPCD_00625	1.61e-192	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MHGEFPCD_00626	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_00627	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MHGEFPCD_00628	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
MHGEFPCD_00629	8.64e-196	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MHGEFPCD_00631	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MHGEFPCD_00632	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MHGEFPCD_00633	4.33e-315	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MHGEFPCD_00634	1.24e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHGEFPCD_00635	2.39e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MHGEFPCD_00636	2.87e-270	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MHGEFPCD_00637	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MHGEFPCD_00638	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MHGEFPCD_00639	2.74e-174	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
MHGEFPCD_00640	2.63e-143	-	-	-	F	-	-	-	ATP-grasp domain
MHGEFPCD_00641	8.37e-135	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHGEFPCD_00642	3.93e-167	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MHGEFPCD_00643	1.31e-186	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
MHGEFPCD_00644	1.15e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_00645	4.51e-315	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MHGEFPCD_00646	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHGEFPCD_00647	8.8e-168	yebC	-	-	M	-	-	-	Membrane
MHGEFPCD_00649	1.48e-119	yebE	-	-	S	-	-	-	UPF0316 protein
MHGEFPCD_00650	2.21e-38	yebG	-	-	S	-	-	-	NETI protein
MHGEFPCD_00651	1.13e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHGEFPCD_00652	1.07e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHGEFPCD_00653	4.29e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHGEFPCD_00654	3.53e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MHGEFPCD_00655	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHGEFPCD_00656	1.91e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHGEFPCD_00657	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHGEFPCD_00658	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHGEFPCD_00659	4.38e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MHGEFPCD_00660	4.22e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHGEFPCD_00661	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MHGEFPCD_00662	1.63e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MHGEFPCD_00663	1.03e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MHGEFPCD_00664	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MHGEFPCD_00665	2.98e-247	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MHGEFPCD_00666	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00667	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MHGEFPCD_00668	8.71e-164	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHGEFPCD_00669	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MHGEFPCD_00670	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHGEFPCD_00671	4.55e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MHGEFPCD_00672	8.91e-249	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MHGEFPCD_00673	1.68e-157	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MHGEFPCD_00674	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHGEFPCD_00675	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHGEFPCD_00676	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHGEFPCD_00677	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHGEFPCD_00678	3.69e-196	yerO	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00679	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHGEFPCD_00680	4.95e-216	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHGEFPCD_00681	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHGEFPCD_00682	7.65e-104	-	-	-	-	-	-	-	-
MHGEFPCD_00683	3e-47	-	-	-	H	-	-	-	ThiF family
MHGEFPCD_00684	2.62e-10	-	-	-	S	-	-	-	Prokaryotic homologs of the JAB domain
MHGEFPCD_00685	2.53e-96	-	-	-	V	-	-	-	HNH nucleases
MHGEFPCD_00686	1.43e-204	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MHGEFPCD_00687	2.64e-173	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MHGEFPCD_00688	3.84e-19	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MHGEFPCD_00689	8.07e-81	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MHGEFPCD_00690	2.38e-96	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MHGEFPCD_00691	1.47e-55	-	-	-	S	-	-	-	Immunity protein 22
MHGEFPCD_00692	1.14e-41	-	-	-	-	-	-	-	-
MHGEFPCD_00693	6.79e-317	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MHGEFPCD_00694	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MHGEFPCD_00697	2.33e-135	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MHGEFPCD_00698	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MHGEFPCD_00699	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MHGEFPCD_00700	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MHGEFPCD_00701	7.74e-121	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MHGEFPCD_00702	4.2e-05	-	-	-	-	-	-	-	-
MHGEFPCD_00703	4.1e-153	yetF	-	-	S	-	-	-	membrane
MHGEFPCD_00704	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MHGEFPCD_00705	1.32e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGEFPCD_00706	6.02e-195	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHGEFPCD_00707	3.08e-176	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
MHGEFPCD_00708	4.82e-142	cysT	-	-	O	ko:K02046	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0555 ABC-type sulfate transport system, permease component
MHGEFPCD_00709	5.95e-135	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG4208 ABC-type sulfate transport system, permease component
MHGEFPCD_00710	1.69e-166	cysA	3.6.3.25	-	P	ko:K02045	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MHGEFPCD_00711	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MHGEFPCD_00712	1.06e-72	-	-	-	H	-	-	-	riboflavin kinase activity
MHGEFPCD_00713	1.54e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MHGEFPCD_00714	2.08e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_00715	2.85e-263	yetM	-	-	CH	-	-	-	FAD binding domain
MHGEFPCD_00716	1.38e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MHGEFPCD_00717	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MHGEFPCD_00719	1.96e-65	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MHGEFPCD_00720	2.96e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHGEFPCD_00721	3.09e-161	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MHGEFPCD_00722	7.47e-07	-	-	-	S	-	-	-	protein homooligomerization
MHGEFPCD_00723	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MHGEFPCD_00724	3.57e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MHGEFPCD_00725	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MHGEFPCD_00726	2.21e-228	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MHGEFPCD_00727	1.78e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MHGEFPCD_00728	1.99e-238	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MHGEFPCD_00729	3.84e-278	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_00730	5.65e-311	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MHGEFPCD_00731	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHGEFPCD_00732	5.07e-156	yfmS	-	-	NT	-	-	-	chemotaxis protein
MHGEFPCD_00733	2.1e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MHGEFPCD_00734	1.2e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHGEFPCD_00735	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHGEFPCD_00736	8.7e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MHGEFPCD_00737	1.25e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MHGEFPCD_00738	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHGEFPCD_00739	4.89e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MHGEFPCD_00740	2.52e-87	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MHGEFPCD_00741	9.5e-239	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MHGEFPCD_00742	1.42e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MHGEFPCD_00743	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MHGEFPCD_00744	1.08e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MHGEFPCD_00745	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MHGEFPCD_00753	3.12e-99	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
MHGEFPCD_00754	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_00755	1.18e-191	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MHGEFPCD_00756	0.0	-	-	-	M	-	-	-	cell wall anchor domain
MHGEFPCD_00757	1.59e-103	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MHGEFPCD_00758	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MHGEFPCD_00759	2.39e-155	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MHGEFPCD_00760	8.33e-228	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MHGEFPCD_00761	5.77e-287	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MHGEFPCD_00762	1.4e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHGEFPCD_00763	2.89e-277	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MHGEFPCD_00764	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MHGEFPCD_00765	4e-155	yflK	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_00766	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MHGEFPCD_00767	1.98e-26	yflI	-	-	-	-	-	-	-
MHGEFPCD_00768	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MHGEFPCD_00769	9.02e-176	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MHGEFPCD_00770	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MHGEFPCD_00771	8.21e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MHGEFPCD_00772	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MHGEFPCD_00773	2.43e-83	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MHGEFPCD_00774	8.64e-106	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHGEFPCD_00775	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MHGEFPCD_00776	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MHGEFPCD_00777	2.71e-314	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_00778	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHGEFPCD_00779	7.96e-164	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MHGEFPCD_00780	2.93e-158	frp	-	-	C	-	-	-	nitroreductase
MHGEFPCD_00781	8.16e-165	yibF	-	-	S	-	-	-	YibE/F-like protein
MHGEFPCD_00782	7.37e-254	yibE	-	-	S	-	-	-	YibE/F-like protein
MHGEFPCD_00783	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MHGEFPCD_00784	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MHGEFPCD_00785	7.5e-238	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHGEFPCD_00786	3.54e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHGEFPCD_00787	6.81e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHGEFPCD_00788	5.73e-251	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_00789	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MHGEFPCD_00790	1.69e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHGEFPCD_00791	1.24e-68	yfkI	-	-	S	-	-	-	gas vesicle protein
MHGEFPCD_00792	1.37e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MHGEFPCD_00793	1.37e-12	-	-	-	-	-	-	-	-
MHGEFPCD_00794	4.15e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_00795	8.42e-239	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MHGEFPCD_00796	3.82e-184	yfkD	-	-	S	-	-	-	YfkD-like protein
MHGEFPCD_00797	3.51e-187	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MHGEFPCD_00798	2.4e-281	yfkA	-	-	S	-	-	-	YfkB-like domain
MHGEFPCD_00799	7.99e-37	yfjT	-	-	-	-	-	-	-
MHGEFPCD_00800	4.36e-199	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MHGEFPCD_00801	2.19e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHGEFPCD_00803	1.06e-234	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MHGEFPCD_00804	5.74e-207	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHGEFPCD_00805	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHGEFPCD_00806	4.65e-47	-	-	-	S	-	-	-	YfzA-like protein
MHGEFPCD_00807	1.21e-244	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHGEFPCD_00808	1.57e-115	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MHGEFPCD_00809	1.74e-105	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHGEFPCD_00810	2.19e-104	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHGEFPCD_00811	3.74e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHGEFPCD_00812	3.79e-272	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHGEFPCD_00813	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHGEFPCD_00814	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MHGEFPCD_00815	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MHGEFPCD_00816	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHGEFPCD_00817	1.82e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MHGEFPCD_00818	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_00819	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MHGEFPCD_00820	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MHGEFPCD_00821	1.36e-82	yfiD3	-	-	S	-	-	-	DoxX
MHGEFPCD_00822	1.65e-205	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MHGEFPCD_00823	5.11e-215	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHGEFPCD_00824	5.62e-126	padR	-	-	K	-	-	-	transcriptional
MHGEFPCD_00825	3.61e-144	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHGEFPCD_00826	2.2e-235	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MHGEFPCD_00827	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MHGEFPCD_00828	2.87e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MHGEFPCD_00829	2.31e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MHGEFPCD_00830	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MHGEFPCD_00831	1.88e-106	yfiV	-	-	K	-	-	-	transcriptional
MHGEFPCD_00832	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHGEFPCD_00833	1.71e-207	yfhB	-	-	S	-	-	-	PhzF family
MHGEFPCD_00834	8.22e-138	yfhC	-	-	C	-	-	-	nitroreductase
MHGEFPCD_00835	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
MHGEFPCD_00837	2.45e-214	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MHGEFPCD_00838	1.05e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MHGEFPCD_00839	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MHGEFPCD_00840	2.86e-268	yfhI	-	-	EGP	-	-	-	-transporter
MHGEFPCD_00842	2.02e-215	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MHGEFPCD_00843	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
MHGEFPCD_00844	4.01e-122	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MHGEFPCD_00845	4.24e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MHGEFPCD_00846	5.37e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MHGEFPCD_00847	1.35e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHGEFPCD_00848	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MHGEFPCD_00849	5.93e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MHGEFPCD_00850	9.18e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MHGEFPCD_00851	1.47e-49	yfhS	-	-	-	-	-	-	-
MHGEFPCD_00852	5.41e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_00853	7.33e-07	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MHGEFPCD_00854	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MHGEFPCD_00855	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MHGEFPCD_00856	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MHGEFPCD_00857	9.11e-240	ygaE	-	-	S	-	-	-	Membrane
MHGEFPCD_00858	6.86e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MHGEFPCD_00859	1.39e-111	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MHGEFPCD_00860	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MHGEFPCD_00861	6.64e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
MHGEFPCD_00862	7.89e-213	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MHGEFPCD_00863	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_00880	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
MHGEFPCD_00881	2.23e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MHGEFPCD_00882	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHGEFPCD_00883	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MHGEFPCD_00885	9.48e-293	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
MHGEFPCD_00886	5.79e-179	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHGEFPCD_00887	1.77e-161	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_00888	2.7e-170	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_00889	1.63e-168	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_00890	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MHGEFPCD_00891	4.68e-234	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MHGEFPCD_00892	4.5e-180	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MHGEFPCD_00893	1.06e-230	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MHGEFPCD_00894	5.58e-184	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHGEFPCD_00895	1.43e-271	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MHGEFPCD_00896	1.18e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHGEFPCD_00897	1.29e-106	ygaO	-	-	-	-	-	-	-
MHGEFPCD_00898	9.41e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_00900	1.11e-146	yhzB	-	-	S	-	-	-	B3/4 domain
MHGEFPCD_00901	2.08e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHGEFPCD_00902	1.21e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
MHGEFPCD_00903	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHGEFPCD_00904	1.33e-138	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MHGEFPCD_00905	8.53e-87	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MHGEFPCD_00906	5.77e-94	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MHGEFPCD_00907	1.23e-07	-	-	-	-	-	-	-	-
MHGEFPCD_00908	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MHGEFPCD_00909	5.45e-279	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MHGEFPCD_00910	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MHGEFPCD_00911	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MHGEFPCD_00912	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MHGEFPCD_00913	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHGEFPCD_00914	4.73e-71	yhcC	-	-	-	-	-	-	-
MHGEFPCD_00915	1.16e-66	-	-	-	-	-	-	-	-
MHGEFPCD_00916	6.69e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_00917	1.78e-162	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_00918	5.54e-214	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_00919	2.6e-208	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHGEFPCD_00920	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MHGEFPCD_00921	2.91e-190	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MHGEFPCD_00922	1.75e-235	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MHGEFPCD_00923	7.04e-306	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHGEFPCD_00924	7.55e-75	yhcM	-	-	-	-	-	-	-
MHGEFPCD_00925	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHGEFPCD_00926	3.33e-207	yhcP	-	-	-	-	-	-	-
MHGEFPCD_00927	4.45e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
MHGEFPCD_00928	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHGEFPCD_00929	2.25e-137	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MHGEFPCD_00930	9.64e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MHGEFPCD_00931	1.88e-92	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MHGEFPCD_00932	6.12e-91	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MHGEFPCD_00933	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MHGEFPCD_00934	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHGEFPCD_00935	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHGEFPCD_00936	5.16e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MHGEFPCD_00937	1.91e-197	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MHGEFPCD_00938	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHGEFPCD_00939	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHGEFPCD_00940	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MHGEFPCD_00941	6.16e-262	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_00942	3.15e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHGEFPCD_00943	5.65e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MHGEFPCD_00944	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
MHGEFPCD_00945	6.94e-70	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MHGEFPCD_00946	1.41e-295	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MHGEFPCD_00947	1.32e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MHGEFPCD_00948	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
MHGEFPCD_00949	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MHGEFPCD_00950	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MHGEFPCD_00951	5.07e-174	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MHGEFPCD_00952	7e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_00953	1.64e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MHGEFPCD_00954	2.62e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_00955	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MHGEFPCD_00956	6.89e-266	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHGEFPCD_00957	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MHGEFPCD_00958	6.88e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MHGEFPCD_00959	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_00960	1.59e-142	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHGEFPCD_00961	2.28e-306	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHGEFPCD_00962	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MHGEFPCD_00963	1.16e-285	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MHGEFPCD_00964	1.57e-300	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHGEFPCD_00965	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHGEFPCD_00966	2.04e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHGEFPCD_00967	8.59e-80	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHGEFPCD_00968	2.58e-165	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MHGEFPCD_00969	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MHGEFPCD_00970	1.83e-259	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MHGEFPCD_00971	2.06e-180	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHGEFPCD_00972	9.46e-199	nodB1	-	-	G	-	-	-	deacetylase
MHGEFPCD_00973	8.4e-198	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHGEFPCD_00974	1.22e-114	pksA	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_00975	1.55e-123	ymcC	-	-	S	-	-	-	Membrane
MHGEFPCD_00976	5.87e-109	-	-	-	T	-	-	-	universal stress protein
MHGEFPCD_00978	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MHGEFPCD_00979	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MHGEFPCD_00980	3.86e-142	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MHGEFPCD_00982	6.66e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MHGEFPCD_00983	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MHGEFPCD_00984	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MHGEFPCD_00985	7.63e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MHGEFPCD_00986	3.88e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MHGEFPCD_00987	2.32e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MHGEFPCD_00988	5.83e-257	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MHGEFPCD_00989	1.03e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MHGEFPCD_00990	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MHGEFPCD_00991	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
MHGEFPCD_00992	1.41e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MHGEFPCD_00993	1.87e-113	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MHGEFPCD_00995	1.18e-174	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MHGEFPCD_00996	5.99e-21	-	-	-	S	-	-	-	YhzD-like protein
MHGEFPCD_00997	3.22e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_00998	2.79e-276	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MHGEFPCD_00999	3.7e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MHGEFPCD_01000	0.0	yhaN	-	-	L	-	-	-	AAA domain
MHGEFPCD_01001	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MHGEFPCD_01002	3.48e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MHGEFPCD_01003	1.53e-184	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHGEFPCD_01004	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MHGEFPCD_01005	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MHGEFPCD_01006	3.33e-146	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MHGEFPCD_01007	2.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MHGEFPCD_01008	4.4e-25	-	-	-	-	-	-	-	-
MHGEFPCD_01009	4.77e-99	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MHGEFPCD_01010	1.69e-258	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHGEFPCD_01011	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHGEFPCD_01012	1.82e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MHGEFPCD_01013	4.32e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MHGEFPCD_01014	1.01e-160	ecsC	-	-	S	-	-	-	EcsC protein family
MHGEFPCD_01015	1.03e-284	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHGEFPCD_01016	3.27e-310	yhfA	-	-	C	-	-	-	membrane
MHGEFPCD_01017	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MHGEFPCD_01018	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHGEFPCD_01019	7.35e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHGEFPCD_01020	5.24e-231	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MHGEFPCD_01021	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHGEFPCD_01022	3.1e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_01023	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MHGEFPCD_01024	1.39e-233	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHGEFPCD_01026	3.65e-251	yhfE	-	-	G	-	-	-	peptidase M42
MHGEFPCD_01027	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHGEFPCD_01029	1.4e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MHGEFPCD_01030	5.31e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MHGEFPCD_01031	2.58e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
MHGEFPCD_01032	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MHGEFPCD_01033	6.81e-86	yhfM	-	-	-	-	-	-	-
MHGEFPCD_01034	1.24e-298	yhfN	-	-	O	-	-	-	Peptidase M48
MHGEFPCD_01035	6.69e-263	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHGEFPCD_01036	3.8e-194	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MHGEFPCD_01037	8.57e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MHGEFPCD_01038	3.37e-251	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MHGEFPCD_01039	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MHGEFPCD_01040	7.56e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MHGEFPCD_01041	4.6e-276	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MHGEFPCD_01042	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MHGEFPCD_01043	3.88e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_01044	9.48e-43	yhzC	-	-	S	-	-	-	IDEAL
MHGEFPCD_01045	1.09e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MHGEFPCD_01046	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MHGEFPCD_01047	1.08e-85	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MHGEFPCD_01048	6.72e-118	-	-	-	S	-	-	-	MepB protein
MHGEFPCD_01050	1.49e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MHGEFPCD_01051	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MHGEFPCD_01052	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
MHGEFPCD_01053	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHGEFPCD_01054	1.37e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MHGEFPCD_01055	5.86e-79	yhjD	-	-	-	-	-	-	-
MHGEFPCD_01056	9.09e-142	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MHGEFPCD_01057	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHGEFPCD_01058	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MHGEFPCD_01059	1.03e-123	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_01060	8.09e-261	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MHGEFPCD_01061	2.64e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_01062	3.71e-140	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
MHGEFPCD_01063	1.79e-122	yhjR	-	-	S	-	-	-	Rubrerythrin
MHGEFPCD_01064	2.88e-159	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MHGEFPCD_01065	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MHGEFPCD_01066	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MHGEFPCD_01067	9.49e-283	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHGEFPCD_01068	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MHGEFPCD_01069	7.31e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MHGEFPCD_01070	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MHGEFPCD_01071	1.09e-82	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MHGEFPCD_01072	5e-32	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MHGEFPCD_01073	9.91e-108	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MHGEFPCD_01074	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MHGEFPCD_01075	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MHGEFPCD_01076	2.25e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MHGEFPCD_01077	8.91e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHGEFPCD_01078	6.36e-78	yisL	-	-	S	-	-	-	UPF0344 protein
MHGEFPCD_01079	1.78e-122	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MHGEFPCD_01080	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHGEFPCD_01081	5.19e-169	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MHGEFPCD_01082	3.19e-312	yisQ	-	-	V	-	-	-	Mate efflux family protein
MHGEFPCD_01083	2.73e-205	yisR	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_01084	4.97e-182	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHGEFPCD_01085	5.97e-198	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MHGEFPCD_01086	2.65e-108	yisT	-	-	S	-	-	-	DinB family
MHGEFPCD_01087	9.57e-112	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MHGEFPCD_01088	2.19e-105	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MHGEFPCD_01089	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHGEFPCD_01090	4.29e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MHGEFPCD_01091	1.59e-206	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MHGEFPCD_01092	3.1e-221	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
MHGEFPCD_01093	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHGEFPCD_01094	1.53e-308	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MHGEFPCD_01096	2.62e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01097	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHGEFPCD_01098	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MHGEFPCD_01099	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MHGEFPCD_01100	1.49e-11	-	-	-	-	-	-	-	-
MHGEFPCD_01101	5.08e-197	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MHGEFPCD_01102	1.06e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MHGEFPCD_01103	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MHGEFPCD_01104	2.36e-105	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MHGEFPCD_01105	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MHGEFPCD_01106	1.18e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MHGEFPCD_01107	1.95e-250	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHGEFPCD_01108	6.29e-291	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHGEFPCD_01109	2.87e-172	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MHGEFPCD_01110	6.59e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MHGEFPCD_01111	1.69e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MHGEFPCD_01112	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MHGEFPCD_01113	5e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHGEFPCD_01114	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MHGEFPCD_01115	5.24e-33	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MHGEFPCD_01116	6.65e-180	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MHGEFPCD_01117	1.67e-134	yjaV	-	-	-	-	-	-	-
MHGEFPCD_01118	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MHGEFPCD_01119	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MHGEFPCD_01120	2.82e-44	yjzB	-	-	-	-	-	-	-
MHGEFPCD_01121	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHGEFPCD_01122	1.29e-298	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHGEFPCD_01123	8.73e-189	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MHGEFPCD_01124	1.69e-231	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01125	2.94e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01126	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MHGEFPCD_01127	4.24e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_01128	1.84e-207	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_01129	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MHGEFPCD_01130	2.51e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MHGEFPCD_01131	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHGEFPCD_01132	1.46e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_01133	3.59e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_01134	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01135	1.42e-216	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01136	5.81e-294	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
MHGEFPCD_01137	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHGEFPCD_01138	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHGEFPCD_01139	4.79e-142	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MHGEFPCD_01140	9.78e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHGEFPCD_01141	1.44e-275	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MHGEFPCD_01142	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MHGEFPCD_01143	3.14e-27	-	-	-	-	-	-	-	-
MHGEFPCD_01144	6.05e-220	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MHGEFPCD_01145	1.22e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MHGEFPCD_01146	1.22e-149	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHGEFPCD_01147	9.98e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01148	3.5e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MHGEFPCD_01149	9.01e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MHGEFPCD_01150	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHGEFPCD_01151	7.85e-210	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MHGEFPCD_01152	5.06e-182	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHGEFPCD_01153	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHGEFPCD_01154	4.88e-178	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHGEFPCD_01155	4.68e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MHGEFPCD_01156	1.42e-271	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MHGEFPCD_01157	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
MHGEFPCD_01158	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHGEFPCD_01159	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHGEFPCD_01160	3.54e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHGEFPCD_01161	3.96e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MHGEFPCD_01162	3.1e-121	yjbX	-	-	S	-	-	-	Spore coat protein
MHGEFPCD_01163	2.1e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MHGEFPCD_01164	4.28e-121	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MHGEFPCD_01165	1.51e-99	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MHGEFPCD_01166	1.02e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
MHGEFPCD_01167	9.7e-71	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MHGEFPCD_01168	2.92e-73	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MHGEFPCD_01171	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MHGEFPCD_01172	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MHGEFPCD_01173	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHGEFPCD_01174	4.12e-47	-	-	-	-	-	-	-	-
MHGEFPCD_01175	3.42e-180	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MHGEFPCD_01176	6.25e-158	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MHGEFPCD_01177	3.38e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MHGEFPCD_01178	4.32e-48	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MHGEFPCD_01179	8.64e-97	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHGEFPCD_01180	2.43e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MHGEFPCD_01181	1.01e-163	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MHGEFPCD_01182	1.04e-266	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHGEFPCD_01183	1.67e-272	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHGEFPCD_01190	2.38e-32	-	-	-	-	-	-	-	-
MHGEFPCD_01192	2.29e-15	-	-	-	-	-	-	-	-
MHGEFPCD_01198	1.67e-12	-	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_01201	5.68e-56	-	-	-	-	-	-	-	-
MHGEFPCD_01204	1.47e-13	yqaS	-	-	L	-	-	-	DNA packaging
MHGEFPCD_01205	1.51e-10	yqaS	-	-	L	-	-	-	DNA packaging
MHGEFPCD_01206	8.84e-211	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MHGEFPCD_01207	2.2e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MHGEFPCD_01208	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
MHGEFPCD_01209	1.06e-106	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_01210	3.02e-278	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MHGEFPCD_01211	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MHGEFPCD_01212	4.52e-237	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MHGEFPCD_01213	7.4e-275	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHGEFPCD_01214	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGEFPCD_01215	8.91e-67	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_01216	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHGEFPCD_01217	1.39e-177	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MHGEFPCD_01218	1.19e-160	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MHGEFPCD_01219	6.86e-46	-	-	-	-	-	-	-	-
MHGEFPCD_01220	6.88e-68	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_01221	2.48e-136	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MHGEFPCD_01223	3.18e-30	yjfB	-	-	S	-	-	-	Putative motility protein
MHGEFPCD_01224	8.23e-88	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MHGEFPCD_01225	2.76e-129	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MHGEFPCD_01226	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MHGEFPCD_01227	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MHGEFPCD_01228	2.45e-286	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHGEFPCD_01229	4.91e-285	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHGEFPCD_01230	1.73e-40	-	-	-	-	-	-	-	-
MHGEFPCD_01231	2.27e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MHGEFPCD_01232	3.12e-153	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MHGEFPCD_01233	1.46e-164	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01234	4.6e-224	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MHGEFPCD_01235	1.48e-119	yjlB	-	-	S	-	-	-	Cupin domain
MHGEFPCD_01236	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MHGEFPCD_01237	6.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MHGEFPCD_01238	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MHGEFPCD_01239	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MHGEFPCD_01240	1.02e-234	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MHGEFPCD_01241	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MHGEFPCD_01242	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MHGEFPCD_01243	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHGEFPCD_01244	8.38e-103	yjoA	-	-	S	-	-	-	DinB family
MHGEFPCD_01245	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MHGEFPCD_01247	4.78e-221	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MHGEFPCD_01248	7.82e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
MHGEFPCD_01249	4.9e-140	yjqB	-	-	S	-	-	-	phage-related replication protein
MHGEFPCD_01250	1.88e-187	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MHGEFPCD_01251	3.1e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MHGEFPCD_01252	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHGEFPCD_01254	1.46e-194	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MHGEFPCD_01258	1.07e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHGEFPCD_01259	1.44e-141	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MHGEFPCD_01260	6.75e-263	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MHGEFPCD_01261	8.55e-303	xkdE3	-	-	S	-	-	-	portal protein
MHGEFPCD_01262	2.29e-116	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MHGEFPCD_01263	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
MHGEFPCD_01264	1.78e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MHGEFPCD_01265	1.66e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MHGEFPCD_01266	2.41e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MHGEFPCD_01267	4.28e-74	xkdJ	-	-	-	-	-	-	-
MHGEFPCD_01268	1.57e-20	-	-	-	-	-	-	-	-
MHGEFPCD_01269	2.31e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MHGEFPCD_01270	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
MHGEFPCD_01271	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MHGEFPCD_01272	4.33e-27	-	-	-	-	-	-	-	-
MHGEFPCD_01273	2.12e-276	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MHGEFPCD_01274	6.56e-145	xkdP	-	-	S	-	-	-	Lysin motif
MHGEFPCD_01275	4.41e-205	xkdQ	-	-	G	-	-	-	NLP P60 protein
MHGEFPCD_01276	5.07e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MHGEFPCD_01277	5.77e-76	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MHGEFPCD_01278	1.78e-211	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHGEFPCD_01279	7.1e-113	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MHGEFPCD_01280	3.63e-37	-	-	-	-	-	-	-	-
MHGEFPCD_01281	2.21e-110	-	-	-	-	-	-	-	-
MHGEFPCD_01283	3.25e-40	xkdX	-	-	-	-	-	-	-
MHGEFPCD_01284	4.28e-176	xepA	-	-	-	-	-	-	-
MHGEFPCD_01285	3.87e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MHGEFPCD_01286	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
MHGEFPCD_01287	5.16e-217	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MHGEFPCD_01288	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MHGEFPCD_01289	1.89e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MHGEFPCD_01290	7.07e-226	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MHGEFPCD_01291	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MHGEFPCD_01292	2.3e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MHGEFPCD_01293	1.23e-227	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MHGEFPCD_01294	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHGEFPCD_01295	4.28e-227	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHGEFPCD_01297	3.96e-271	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHGEFPCD_01298	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MHGEFPCD_01300	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MHGEFPCD_01301	1.39e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_01302	1.33e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHGEFPCD_01303	3.91e-244	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01304	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHGEFPCD_01305	7.67e-224	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MHGEFPCD_01306	2.38e-252	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MHGEFPCD_01307	2.55e-216	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHGEFPCD_01308	2.31e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_01309	2.41e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MHGEFPCD_01310	3.44e-203	ykgA	-	-	E	-	-	-	Amidinotransferase
MHGEFPCD_01311	3.06e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MHGEFPCD_01312	1.5e-129	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHGEFPCD_01313	4.09e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MHGEFPCD_01314	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MHGEFPCD_01315	6.78e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MHGEFPCD_01316	2.41e-259	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHGEFPCD_01317	7.94e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHGEFPCD_01318	6.87e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MHGEFPCD_01319	7.24e-113	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MHGEFPCD_01320	1.92e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MHGEFPCD_01321	5.58e-78	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHGEFPCD_01323	1.67e-273	-	-	-	M	-	-	-	Glycosyl transferase family 2
MHGEFPCD_01324	1.95e-155	-	-	-	K	-	-	-	Collagen triple helix repeat
MHGEFPCD_01325	9.79e-278	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_01326	1.57e-155	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHGEFPCD_01327	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHGEFPCD_01328	7.39e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHGEFPCD_01329	3.93e-184	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHGEFPCD_01330	1.32e-170	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MHGEFPCD_01331	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_01332	2.81e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MHGEFPCD_01333	3.79e-311	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MHGEFPCD_01335	8.66e-310	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MHGEFPCD_01336	1.01e-68	tnrA	-	-	K	-	-	-	transcriptional
MHGEFPCD_01337	1.11e-23	-	-	-	-	-	-	-	-
MHGEFPCD_01338	5.25e-37	ykoL	-	-	-	-	-	-	-
MHGEFPCD_01339	5.46e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MHGEFPCD_01340	3.81e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MHGEFPCD_01341	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MHGEFPCD_01342	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHGEFPCD_01343	3.36e-130	ykoX	-	-	S	-	-	-	membrane-associated protein
MHGEFPCD_01344	1.01e-173	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHGEFPCD_01345	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_01346	3.6e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MHGEFPCD_01347	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MHGEFPCD_01348	6.86e-163	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MHGEFPCD_01349	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MHGEFPCD_01350	4.63e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MHGEFPCD_01351	6.05e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MHGEFPCD_01352	3.07e-32	ykzE	-	-	-	-	-	-	-
MHGEFPCD_01353	4.36e-240	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHGEFPCD_01354	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_01355	7.6e-113	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHGEFPCD_01357	6.3e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MHGEFPCD_01358	2.44e-287	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MHGEFPCD_01359	7.79e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHGEFPCD_01360	6.03e-290	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MHGEFPCD_01361	2.25e-288	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MHGEFPCD_01362	3.17e-173	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MHGEFPCD_01363	1.3e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MHGEFPCD_01364	5.24e-124	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MHGEFPCD_01366	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MHGEFPCD_01367	3.91e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MHGEFPCD_01368	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MHGEFPCD_01369	1.17e-176	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MHGEFPCD_01370	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MHGEFPCD_01371	3.65e-230	ykvI	-	-	S	-	-	-	membrane
MHGEFPCD_01372	8.19e-248	-	-	-	-	-	-	-	-
MHGEFPCD_01373	5.49e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHGEFPCD_01374	8.88e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MHGEFPCD_01375	1.76e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHGEFPCD_01376	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHGEFPCD_01377	1.01e-80	ykvN	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_01378	2.2e-171	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MHGEFPCD_01379	4.53e-41	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHGEFPCD_01380	2.09e-59	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MHGEFPCD_01381	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01382	7.17e-39	-	-	-	-	-	-	-	-
MHGEFPCD_01383	4.17e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MHGEFPCD_01384	7.63e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHGEFPCD_01385	2.99e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
MHGEFPCD_01386	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MHGEFPCD_01387	4.71e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MHGEFPCD_01389	2.03e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_01390	2.78e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MHGEFPCD_01391	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_01392	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MHGEFPCD_01393	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHGEFPCD_01394	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_01395	4.12e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MHGEFPCD_01396	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHGEFPCD_01397	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHGEFPCD_01398	1.38e-84	-	-	-	-	-	-	-	-
MHGEFPCD_01399	8.42e-168	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MHGEFPCD_01400	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHGEFPCD_01401	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_01402	1.62e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MHGEFPCD_01403	6.38e-15	-	-	-	-	-	-	-	-
MHGEFPCD_01404	3.2e-212	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MHGEFPCD_01405	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
MHGEFPCD_01406	1.32e-307	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_01407	3.62e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01408	2.12e-196	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MHGEFPCD_01409	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_01411	1.82e-295	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MHGEFPCD_01412	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01413	5.29e-121	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MHGEFPCD_01414	3.09e-35	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MHGEFPCD_01415	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
MHGEFPCD_01416	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_01417	3.15e-117	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MHGEFPCD_01418	5.83e-221	ykuO	-	-	-	-	-	-	-
MHGEFPCD_01419	2.16e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MHGEFPCD_01420	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHGEFPCD_01421	6.85e-277	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHGEFPCD_01422	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MHGEFPCD_01423	1.73e-178	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MHGEFPCD_01424	1.3e-100	ykuV	-	-	CO	-	-	-	thiol-disulfide
MHGEFPCD_01425	3.04e-126	rok	-	-	K	-	-	-	Repressor of ComK
MHGEFPCD_01426	1.03e-217	yknT	-	-	-	ko:K06437	-	ko00000	-
MHGEFPCD_01427	3.89e-139	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHGEFPCD_01428	1.71e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHGEFPCD_01429	9.69e-310	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MHGEFPCD_01430	5.32e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MHGEFPCD_01431	1.69e-107	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MHGEFPCD_01432	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHGEFPCD_01433	8.96e-138	yknW	-	-	S	-	-	-	Yip1 domain
MHGEFPCD_01434	9.47e-245	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHGEFPCD_01435	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_01436	7.01e-268	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MHGEFPCD_01437	1.6e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_01438	4.75e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MHGEFPCD_01439	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHGEFPCD_01440	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHGEFPCD_01441	1.5e-49	ykoA	-	-	-	-	-	-	-
MHGEFPCD_01442	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHGEFPCD_01443	1.79e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHGEFPCD_01444	1.2e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHGEFPCD_01445	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MHGEFPCD_01446	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MHGEFPCD_01447	7.46e-59	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MHGEFPCD_01448	2.39e-312	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MHGEFPCD_01449	1.76e-195	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MHGEFPCD_01450	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MHGEFPCD_01451	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHGEFPCD_01452	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHGEFPCD_01453	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MHGEFPCD_01454	3.56e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MHGEFPCD_01455	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHGEFPCD_01456	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MHGEFPCD_01457	6.53e-133	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MHGEFPCD_01458	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHGEFPCD_01459	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01460	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
MHGEFPCD_01461	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01462	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01463	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01464	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01465	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
MHGEFPCD_01466	4.74e-267	-	-	-	V	-	-	-	Beta-lactamase
MHGEFPCD_01467	6.68e-262	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHGEFPCD_01468	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHGEFPCD_01469	5.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHGEFPCD_01470	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHGEFPCD_01471	1.38e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MHGEFPCD_01472	1.81e-185	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MHGEFPCD_01473	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MHGEFPCD_01474	9.4e-57	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MHGEFPCD_01475	8.15e-155	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MHGEFPCD_01476	7.89e-32	ykzI	-	-	-	-	-	-	-
MHGEFPCD_01477	1.35e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MHGEFPCD_01478	3.08e-107	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MHGEFPCD_01479	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MHGEFPCD_01480	1.19e-235	ylaA	-	-	-	-	-	-	-
MHGEFPCD_01481	7.37e-59	ylaB	-	-	-	-	-	-	-
MHGEFPCD_01482	7.8e-119	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_01484	4.01e-62	ylaE	-	-	-	-	-	-	-
MHGEFPCD_01485	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MHGEFPCD_01486	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MHGEFPCD_01487	2.44e-65	-	-	-	S	-	-	-	YlaH-like protein
MHGEFPCD_01488	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01489	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHGEFPCD_01490	1.56e-312	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MHGEFPCD_01491	1.23e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHGEFPCD_01492	1e-218	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MHGEFPCD_01493	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MHGEFPCD_01494	8.22e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHGEFPCD_01495	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHGEFPCD_01496	3.88e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHGEFPCD_01497	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHGEFPCD_01498	6.83e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHGEFPCD_01499	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHGEFPCD_01500	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHGEFPCD_01501	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHGEFPCD_01502	8.82e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MHGEFPCD_01503	4.12e-79	ylbA	-	-	S	-	-	-	YugN-like family
MHGEFPCD_01504	9.59e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MHGEFPCD_01505	3.26e-254	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MHGEFPCD_01506	8.47e-87	ylbD	-	-	S	-	-	-	Putative coat protein
MHGEFPCD_01507	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MHGEFPCD_01508	3.33e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MHGEFPCD_01509	3.94e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
MHGEFPCD_01511	7.68e-116	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MHGEFPCD_01512	8.3e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHGEFPCD_01513	5.88e-277	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MHGEFPCD_01514	2.48e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MHGEFPCD_01515	5.31e-241	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MHGEFPCD_01516	1.5e-294	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MHGEFPCD_01517	3.3e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MHGEFPCD_01518	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MHGEFPCD_01519	8.95e-111	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHGEFPCD_01520	1.14e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
MHGEFPCD_01521	6.57e-208	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHGEFPCD_01522	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHGEFPCD_01523	3.7e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MHGEFPCD_01524	4.08e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHGEFPCD_01525	1.98e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
MHGEFPCD_01526	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHGEFPCD_01527	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MHGEFPCD_01528	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHGEFPCD_01529	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHGEFPCD_01530	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHGEFPCD_01531	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHGEFPCD_01532	1.9e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHGEFPCD_01533	9.58e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MHGEFPCD_01534	2.67e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHGEFPCD_01535	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHGEFPCD_01536	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHGEFPCD_01537	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MHGEFPCD_01538	5.79e-218	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHGEFPCD_01539	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_01540	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_01541	1.14e-186	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHGEFPCD_01542	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MHGEFPCD_01543	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
MHGEFPCD_01544	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MHGEFPCD_01545	1.44e-158	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHGEFPCD_01546	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHGEFPCD_01547	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MHGEFPCD_01548	6.12e-182	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MHGEFPCD_01549	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MHGEFPCD_01550	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHGEFPCD_01551	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MHGEFPCD_01552	1.02e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHGEFPCD_01553	1.26e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MHGEFPCD_01554	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHGEFPCD_01555	1.62e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MHGEFPCD_01556	5.13e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MHGEFPCD_01557	7.77e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHGEFPCD_01558	3.09e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MHGEFPCD_01559	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MHGEFPCD_01560	4.31e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHGEFPCD_01561	6.05e-221	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHGEFPCD_01562	6.07e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHGEFPCD_01563	7.37e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHGEFPCD_01565	4.03e-180	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MHGEFPCD_01566	8.54e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MHGEFPCD_01567	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MHGEFPCD_01568	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MHGEFPCD_01569	2.06e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MHGEFPCD_01570	2.92e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MHGEFPCD_01571	1.04e-104	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MHGEFPCD_01572	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MHGEFPCD_01573	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MHGEFPCD_01574	2.14e-198	yloC	-	-	S	-	-	-	stress-induced protein
MHGEFPCD_01575	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MHGEFPCD_01576	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MHGEFPCD_01577	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHGEFPCD_01578	1.03e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHGEFPCD_01579	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHGEFPCD_01580	2.04e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHGEFPCD_01581	4.56e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHGEFPCD_01582	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHGEFPCD_01583	8.79e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHGEFPCD_01584	2.37e-176	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MHGEFPCD_01585	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MHGEFPCD_01586	7.27e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHGEFPCD_01587	1.19e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MHGEFPCD_01588	6.42e-154	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MHGEFPCD_01589	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MHGEFPCD_01590	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01591	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MHGEFPCD_01592	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MHGEFPCD_01593	2.4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MHGEFPCD_01594	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHGEFPCD_01595	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHGEFPCD_01596	1.28e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHGEFPCD_01597	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHGEFPCD_01598	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MHGEFPCD_01599	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHGEFPCD_01600	1.23e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHGEFPCD_01601	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MHGEFPCD_01602	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHGEFPCD_01603	1.29e-181	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MHGEFPCD_01604	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHGEFPCD_01605	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHGEFPCD_01606	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MHGEFPCD_01607	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MHGEFPCD_01608	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
MHGEFPCD_01609	8.76e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHGEFPCD_01610	1.98e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MHGEFPCD_01611	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHGEFPCD_01612	5.09e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHGEFPCD_01613	8.29e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHGEFPCD_01614	0.0	ylqG	-	-	-	-	-	-	-
MHGEFPCD_01615	4.88e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MHGEFPCD_01616	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHGEFPCD_01617	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHGEFPCD_01618	2.1e-215	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MHGEFPCD_01619	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHGEFPCD_01620	2.22e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHGEFPCD_01621	6.29e-220	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MHGEFPCD_01622	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHGEFPCD_01623	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHGEFPCD_01624	2.65e-173	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHGEFPCD_01625	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHGEFPCD_01626	1.07e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MHGEFPCD_01627	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MHGEFPCD_01628	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MHGEFPCD_01629	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHGEFPCD_01630	1.38e-122	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MHGEFPCD_01631	5.19e-309	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHGEFPCD_01632	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MHGEFPCD_01633	8.02e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MHGEFPCD_01634	6.35e-262	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MHGEFPCD_01635	5.15e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MHGEFPCD_01636	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MHGEFPCD_01637	7.38e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MHGEFPCD_01638	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHGEFPCD_01639	6.97e-247	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHGEFPCD_01640	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MHGEFPCD_01641	5.4e-143	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MHGEFPCD_01642	6.02e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MHGEFPCD_01643	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MHGEFPCD_01644	2.84e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MHGEFPCD_01645	1.03e-241	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHGEFPCD_01646	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHGEFPCD_01647	8.49e-245	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MHGEFPCD_01648	1.05e-198	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MHGEFPCD_01649	4.97e-249	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHGEFPCD_01650	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MHGEFPCD_01651	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MHGEFPCD_01652	5.91e-143	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHGEFPCD_01653	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHGEFPCD_01654	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_01655	4.12e-94	ylxL	-	-	-	-	-	-	-
MHGEFPCD_01656	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MHGEFPCD_01657	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHGEFPCD_01658	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MHGEFPCD_01659	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHGEFPCD_01660	1.57e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHGEFPCD_01661	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MHGEFPCD_01662	2.2e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHGEFPCD_01663	1.1e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MHGEFPCD_01664	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHGEFPCD_01665	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHGEFPCD_01666	5.66e-106	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MHGEFPCD_01667	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MHGEFPCD_01668	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MHGEFPCD_01669	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MHGEFPCD_01670	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHGEFPCD_01671	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MHGEFPCD_01672	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHGEFPCD_01673	1.48e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHGEFPCD_01674	4.31e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MHGEFPCD_01675	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHGEFPCD_01676	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHGEFPCD_01677	1.02e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MHGEFPCD_01678	4.85e-298	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MHGEFPCD_01679	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MHGEFPCD_01680	1.91e-205	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MHGEFPCD_01681	1.93e-137	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHGEFPCD_01682	3.36e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHGEFPCD_01683	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHGEFPCD_01684	2.93e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHGEFPCD_01685	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHGEFPCD_01686	2.27e-166	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MHGEFPCD_01687	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
MHGEFPCD_01688	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MHGEFPCD_01689	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_01690	3.16e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_01691	2.83e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_01692	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MHGEFPCD_01693	1.12e-306	albE	-	-	S	-	-	-	Peptidase M16
MHGEFPCD_01694	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
MHGEFPCD_01695	2.88e-164	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHGEFPCD_01696	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MHGEFPCD_01697	3.14e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MHGEFPCD_01698	5.76e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MHGEFPCD_01699	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHGEFPCD_01700	1.33e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MHGEFPCD_01701	3.06e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHGEFPCD_01702	3.53e-275	pbpX	-	-	V	-	-	-	Beta-lactamase
MHGEFPCD_01703	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MHGEFPCD_01704	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MHGEFPCD_01705	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MHGEFPCD_01706	1.38e-249	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MHGEFPCD_01707	8.65e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHGEFPCD_01708	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHGEFPCD_01709	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MHGEFPCD_01710	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MHGEFPCD_01711	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHGEFPCD_01712	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHGEFPCD_01713	8.88e-50	-	-	-	L	-	-	-	Phage integrase family
MHGEFPCD_01714	2.3e-29	-	-	-	-	-	-	-	-
MHGEFPCD_01718	8.17e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MHGEFPCD_01719	4.05e-208	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHGEFPCD_01720	3.04e-232	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MHGEFPCD_01721	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHGEFPCD_01722	2.07e-46	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MHGEFPCD_01723	1.48e-308	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MHGEFPCD_01724	4.33e-187	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MHGEFPCD_01725	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MHGEFPCD_01726	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MHGEFPCD_01727	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01728	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_01729	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MHGEFPCD_01730	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MHGEFPCD_01731	3.24e-292	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHGEFPCD_01732	4.27e-102	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MHGEFPCD_01733	6.07e-151	yoaK	-	-	S	-	-	-	Membrane
MHGEFPCD_01734	2.78e-82	ymzB	-	-	-	-	-	-	-
MHGEFPCD_01735	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MHGEFPCD_01736	6.08e-06	-	-	-	-	-	-	-	-
MHGEFPCD_01737	1.61e-162	ymaC	-	-	S	-	-	-	Replication protein
MHGEFPCD_01738	1.71e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MHGEFPCD_01739	1.06e-71	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MHGEFPCD_01740	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MHGEFPCD_01742	5.96e-77	ymaF	-	-	S	-	-	-	YmaF family
MHGEFPCD_01743	2.1e-218	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHGEFPCD_01744	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHGEFPCD_01745	8.21e-57	-	-	-	-	-	-	-	-
MHGEFPCD_01746	9.42e-29	ymzA	-	-	-	-	-	-	-
MHGEFPCD_01747	4.63e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MHGEFPCD_01748	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGEFPCD_01749	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGEFPCD_01750	7.49e-142	ymaB	-	-	S	-	-	-	MutT family
MHGEFPCD_01751	3.75e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MHGEFPCD_01752	3.14e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MHGEFPCD_01753	7.72e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHGEFPCD_01754	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHGEFPCD_01755	4.39e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MHGEFPCD_01756	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MHGEFPCD_01757	2.23e-192	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MHGEFPCD_01759	1.76e-108	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MHGEFPCD_01760	7.74e-121	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
MHGEFPCD_01761	1e-170	-	-	-	V	-	-	-	HNH endonuclease
MHGEFPCD_01762	3.32e-237	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MHGEFPCD_01763	1.7e-96	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MHGEFPCD_01764	1.71e-108	-	-	-	S	ko:K21490	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
MHGEFPCD_01767	5.64e-215	-	-	-	S	-	-	-	amine dehydrogenase activity
MHGEFPCD_01769	2.96e-161	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MHGEFPCD_01770	3.63e-53	-	-	-	S	-	-	-	YolD-like protein
MHGEFPCD_01771	3.07e-283	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHGEFPCD_01772	1.31e-267	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHGEFPCD_01773	1.46e-06	-	-	-	-	-	-	-	-
MHGEFPCD_01775	3.04e-44	-	-	-	S	-	-	-	Bacteriophage holin
MHGEFPCD_01777	1.13e-92	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MHGEFPCD_01778	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
MHGEFPCD_01779	2.84e-136	-	-	-	-	-	-	-	-
MHGEFPCD_01781	0.000856	-	-	-	-	-	-	-	-
MHGEFPCD_01782	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
MHGEFPCD_01783	5.85e-107	-	-	-	S	-	-	-	Phage tail protein
MHGEFPCD_01784	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
MHGEFPCD_01785	4.96e-71	-	-	-	-	-	-	-	-
MHGEFPCD_01788	9.99e-82	-	-	-	S	-	-	-	DNA integration
MHGEFPCD_01789	1.64e-67	-	-	-	-	-	-	-	-
MHGEFPCD_01790	3.59e-76	-	-	-	-	-	-	-	-
MHGEFPCD_01793	4.11e-98	-	-	-	-	-	-	-	-
MHGEFPCD_01794	3.02e-65	-	-	-	-	-	-	-	-
MHGEFPCD_01796	2.52e-117	-	-	-	-	-	-	-	-
MHGEFPCD_01797	6.89e-114	-	-	-	-	-	-	-	-
MHGEFPCD_01798	5.15e-112	-	-	-	-	-	-	-	-
MHGEFPCD_01799	9.58e-133	-	-	-	-	-	-	-	-
MHGEFPCD_01801	8.94e-82	-	-	-	-	-	-	-	-
MHGEFPCD_01802	4.47e-103	-	-	-	-	-	-	-	-
MHGEFPCD_01803	1.34e-233	-	-	-	-	-	-	-	-
MHGEFPCD_01804	1.62e-118	-	-	-	-	-	-	-	-
MHGEFPCD_01805	5.71e-292	-	-	-	-	-	-	-	-
MHGEFPCD_01806	0.0	-	-	-	-	-	-	-	-
MHGEFPCD_01807	0.0	-	-	-	S	-	-	-	Terminase-like family
MHGEFPCD_01808	1.74e-222	-	-	-	-	-	-	-	-
MHGEFPCD_01813	6.9e-278	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
MHGEFPCD_01816	1.19e-252	-	-	-	-	-	-	-	-
MHGEFPCD_01817	7.93e-46	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHGEFPCD_01818	0.0	-	-	-	-	-	-	-	-
MHGEFPCD_01822	2.84e-65	-	-	-	D	-	-	-	Tubulin/FtsZ family, GTPase domain
MHGEFPCD_01826	2.03e-274	-	-	-	-	-	-	-	-
MHGEFPCD_01827	4.19e-05	-	-	-	L	-	-	-	SNF2 family N-terminal domain
MHGEFPCD_01828	1.13e-249	-	-	-	L	-	-	-	Domain of unknown function (DUF4942)
MHGEFPCD_01834	8.16e-16	-	-	-	I	-	-	-	Acyltransferase family
MHGEFPCD_01835	8.38e-60	-	-	-	-	-	-	-	-
MHGEFPCD_01844	1.96e-51	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MHGEFPCD_01845	5.37e-80	-	-	-	-	-	-	-	-
MHGEFPCD_01852	2.83e-240	-	-	-	-	-	-	-	-
MHGEFPCD_01853	1.6e-34	-	-	-	-	-	-	-	-
MHGEFPCD_01858	3.19e-08	-	-	-	S	-	-	-	YopX protein
MHGEFPCD_01873	8.68e-68	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
MHGEFPCD_01875	5.37e-60	-	-	-	-	-	-	-	-
MHGEFPCD_01877	3.89e-176	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
MHGEFPCD_01878	9.06e-159	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MHGEFPCD_01880	3.18e-24	-	-	-	S	-	-	-	YopX protein
MHGEFPCD_01882	5.82e-103	-	-	-	S	-	-	-	Pfam:DUF867
MHGEFPCD_01883	2.56e-278	-	-	-	M	-	-	-	Parallel beta-helix repeats
MHGEFPCD_01887	6.03e-197	-	-	-	-	-	-	-	-
MHGEFPCD_01888	7.29e-219	-	-	-	L	-	-	-	AAA domain
MHGEFPCD_01889	2.7e-104	-	-	-	-	-	-	-	-
MHGEFPCD_01890	0.0	-	-	-	J	-	-	-	DnaB-like helicase C terminal domain
MHGEFPCD_01891	3.16e-259	-	-	-	L	-	-	-	DNA primase activity
MHGEFPCD_01892	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MHGEFPCD_01893	0.0	-	-	-	S	-	-	-	Bacterial DNA polymerase III alpha subunit
MHGEFPCD_01894	7.47e-29	-	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_01897	2.66e-88	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
MHGEFPCD_01898	7.06e-107	-	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl synthetase-associated domain
MHGEFPCD_01899	3.02e-263	-	2.4.2.12	-	H	ko:K03462	ko00760,ko01100,ko04621,map00760,map01100,map04621	ko00000,ko00001,ko01000	Nicotinate phosphoribosyltransferase (NAPRTase) family
MHGEFPCD_01919	7.6e-74	-	-	-	S	-	-	-	NrdI Flavodoxin like
MHGEFPCD_01920	1.78e-156	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGEFPCD_01921	1.54e-47	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGEFPCD_01922	5.97e-203	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGEFPCD_01925	3.29e-232	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHGEFPCD_01926	1.17e-42	-	-	-	O	-	-	-	Glutaredoxin
MHGEFPCD_01928	5.9e-66	-	-	-	S	-	-	-	Peptidyl-tRNA hydrolase PTH2
MHGEFPCD_01929	3.23e-92	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MHGEFPCD_01935	1.77e-123	-	-	-	S	-	-	-	Thymidylate synthase
MHGEFPCD_01936	2.02e-07	-	-	-	S	-	-	-	nucleic acid binding
MHGEFPCD_01937	1.82e-58	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHGEFPCD_01938	1.8e-37	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHGEFPCD_01941	2.2e-62	-	-	-	-	-	-	-	-
MHGEFPCD_01945	1.02e-192	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MHGEFPCD_01948	1.93e-118	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHGEFPCD_01949	5.62e-36	-	-	-	-	-	-	-	-
MHGEFPCD_01950	1.15e-40	-	-	-	-	-	-	-	-
MHGEFPCD_01951	7.12e-41	-	-	-	S	-	-	-	nuclease activity
MHGEFPCD_01954	2.49e-28	-	-	-	-	-	-	-	-
MHGEFPCD_01955	9.47e-94	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
MHGEFPCD_01956	2.1e-22	-	-	-	N	-	-	-	PFAM YcfA family protein
MHGEFPCD_01958	5.22e-57	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MHGEFPCD_01963	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MHGEFPCD_01964	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MHGEFPCD_01965	1.95e-272	xylR	-	-	GK	-	-	-	ROK family
MHGEFPCD_01966	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MHGEFPCD_01967	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MHGEFPCD_01968	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MHGEFPCD_01972	1.28e-26	-	-	-	-	-	-	-	-
MHGEFPCD_01973	1.25e-152	yobV	-	-	K	-	-	-	WYL domain
MHGEFPCD_01974	6.73e-87	dinB	-	-	S	-	-	-	DinB family
MHGEFPCD_01975	1.03e-237	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MHGEFPCD_01976	6.73e-23	-	-	-	-	-	-	-	-
MHGEFPCD_01977	5.74e-26	yoaW	-	-	-	-	-	-	-
MHGEFPCD_01978	1.59e-05	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MHGEFPCD_01979	3.68e-181	yoaP	-	-	K	-	-	-	YoaP-like
MHGEFPCD_01980	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MHGEFPCD_01981	3.3e-113	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MHGEFPCD_01982	1.15e-57	-	-	-	-	-	-	-	-
MHGEFPCD_01983	2.22e-126	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_01985	7.35e-35	yoaF	-	-	-	-	-	-	-
MHGEFPCD_01986	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHGEFPCD_01987	1.72e-245	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHGEFPCD_01988	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MHGEFPCD_01989	4.46e-261	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MHGEFPCD_01990	3.52e-175	yoxB	-	-	-	-	-	-	-
MHGEFPCD_01991	5.9e-57	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHGEFPCD_01992	1.73e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_01993	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHGEFPCD_01994	3.42e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHGEFPCD_01995	2.31e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHGEFPCD_01996	1.4e-203	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_01997	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MHGEFPCD_01998	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHGEFPCD_01999	1.03e-65	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MHGEFPCD_02000	2.42e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHGEFPCD_02001	1.5e-198	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_02002	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHGEFPCD_02003	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
MHGEFPCD_02004	3.38e-256	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
MHGEFPCD_02005	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MHGEFPCD_02006	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MHGEFPCD_02007	1.62e-124	-	-	-	L	-	-	-	Integrase
MHGEFPCD_02009	3.68e-125	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MHGEFPCD_02010	7.44e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
MHGEFPCD_02011	2.25e-238	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MHGEFPCD_02012	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MHGEFPCD_02013	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02014	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02015	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02016	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02017	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
MHGEFPCD_02018	6.82e-85	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MHGEFPCD_02019	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MHGEFPCD_02020	5.35e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MHGEFPCD_02021	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHGEFPCD_02022	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MHGEFPCD_02023	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MHGEFPCD_02024	1.48e-215	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MHGEFPCD_02025	1.01e-177	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MHGEFPCD_02026	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHGEFPCD_02027	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MHGEFPCD_02028	1.25e-206	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHGEFPCD_02029	2.26e-95	yngA	-	-	S	-	-	-	membrane
MHGEFPCD_02030	5.24e-185	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MHGEFPCD_02031	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MHGEFPCD_02032	1.08e-270	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHGEFPCD_02033	2.49e-165	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MHGEFPCD_02034	1.94e-247	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHGEFPCD_02035	1.77e-282	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHGEFPCD_02036	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MHGEFPCD_02037	5.16e-161	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHGEFPCD_02038	1.51e-155	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHGEFPCD_02039	4.1e-178	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHGEFPCD_02040	1.36e-287	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHGEFPCD_02041	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02042	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02043	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_02044	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MHGEFPCD_02045	0.0	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MHGEFPCD_02046	1.54e-163	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MHGEFPCD_02047	5.91e-313	-	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_02048	3.64e-70	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
MHGEFPCD_02049	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MHGEFPCD_02050	1.67e-269	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
MHGEFPCD_02051	1.67e-15	-	-	-	-	-	-	-	-
MHGEFPCD_02053	4.05e-82	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHGEFPCD_02054	1.79e-92	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
MHGEFPCD_02055	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MHGEFPCD_02056	1.04e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MHGEFPCD_02057	3.31e-198	yndG	-	-	S	-	-	-	DoxX-like family
MHGEFPCD_02058	1.53e-284	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
MHGEFPCD_02059	6.12e-232	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MHGEFPCD_02060	1.44e-191	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_02061	2.29e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MHGEFPCD_02062	5.27e-147	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MHGEFPCD_02063	1.71e-241	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MHGEFPCD_02064	1.01e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MHGEFPCD_02065	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MHGEFPCD_02066	1.82e-63	ynfC	-	-	-	-	-	-	-
MHGEFPCD_02067	3.14e-19	-	-	-	-	-	-	-	-
MHGEFPCD_02068	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHGEFPCD_02069	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHGEFPCD_02070	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MHGEFPCD_02071	1.83e-120	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHGEFPCD_02072	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MHGEFPCD_02073	7.79e-70	yneQ	-	-	-	-	-	-	-
MHGEFPCD_02074	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MHGEFPCD_02075	4.24e-45	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MHGEFPCD_02077	1.65e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHGEFPCD_02078	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHGEFPCD_02079	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MHGEFPCD_02080	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MHGEFPCD_02081	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MHGEFPCD_02082	4.83e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MHGEFPCD_02083	6.5e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MHGEFPCD_02084	2.47e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MHGEFPCD_02085	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MHGEFPCD_02086	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MHGEFPCD_02087	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MHGEFPCD_02088	4.4e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MHGEFPCD_02089	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHGEFPCD_02090	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MHGEFPCD_02091	5.22e-145	yneB	-	-	L	-	-	-	resolvase
MHGEFPCD_02092	2.89e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHGEFPCD_02093	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHGEFPCD_02095	6.45e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MHGEFPCD_02096	2.56e-184	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
MHGEFPCD_02097	4.12e-10	-	-	-	-	-	-	-	-
MHGEFPCD_02098	2.47e-183	yndL	-	-	S	-	-	-	Replication protein
MHGEFPCD_02099	1.49e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MHGEFPCD_02100	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MHGEFPCD_02102	6.37e-125	yvgO	-	-	-	-	-	-	-
MHGEFPCD_02104	1.3e-85	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MHGEFPCD_02105	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MHGEFPCD_02106	1.65e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
MHGEFPCD_02107	2.8e-256	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_02108	1.16e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MHGEFPCD_02111	1.08e-54	-	-	-	-	-	-	-	-
MHGEFPCD_02113	1.57e-66	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
MHGEFPCD_02114	1.06e-65	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MHGEFPCD_02115	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MHGEFPCD_02116	3.67e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MHGEFPCD_02117	4.85e-169	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MHGEFPCD_02118	1.86e-122	yobS	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02119	2.41e-175	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHGEFPCD_02120	3.86e-119	yobW	-	-	-	-	-	-	-
MHGEFPCD_02121	6.33e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MHGEFPCD_02122	2.31e-155	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHGEFPCD_02123	8.99e-116	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MHGEFPCD_02124	4.8e-179	-	-	-	J	-	-	-	Protein required for attachment to host cells
MHGEFPCD_02125	3.78e-122	yocC	-	-	-	-	-	-	-
MHGEFPCD_02126	1.02e-235	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MHGEFPCD_02128	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MHGEFPCD_02129	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHGEFPCD_02130	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHGEFPCD_02132	5.24e-78	yocK	-	-	T	-	-	-	general stress protein
MHGEFPCD_02133	3.83e-13	yocL	-	-	-	-	-	-	-
MHGEFPCD_02134	3.51e-13	yocN	-	-	-	-	-	-	-
MHGEFPCD_02135	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHGEFPCD_02136	5.58e-59	yozN	-	-	-	-	-	-	-
MHGEFPCD_02137	6.36e-50	yocN	-	-	-	-	-	-	-
MHGEFPCD_02138	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
MHGEFPCD_02140	4.69e-43	yozC	-	-	-	-	-	-	-
MHGEFPCD_02141	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHGEFPCD_02142	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MHGEFPCD_02143	8.22e-213	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MHGEFPCD_02144	2.93e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHGEFPCD_02145	1.63e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MHGEFPCD_02146	2.05e-176	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MHGEFPCD_02147	1.05e-262	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHGEFPCD_02148	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHGEFPCD_02149	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MHGEFPCD_02150	1.2e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MHGEFPCD_02151	4.23e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHGEFPCD_02152	1.74e-292	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MHGEFPCD_02153	5.76e-286	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MHGEFPCD_02154	1.91e-143	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHGEFPCD_02156	2.79e-309	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MHGEFPCD_02157	3.39e-192	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHGEFPCD_02158	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MHGEFPCD_02159	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MHGEFPCD_02160	1.05e-30	-	-	-	-	-	-	-	-
MHGEFPCD_02161	1.03e-210	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MHGEFPCD_02162	4.68e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MHGEFPCD_02164	2.59e-89	iolK	-	-	S	-	-	-	tautomerase
MHGEFPCD_02165	1.59e-91	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MHGEFPCD_02166	2.42e-74	yodB	-	-	K	-	-	-	transcriptional
MHGEFPCD_02167	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
MHGEFPCD_02168	1.46e-141	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MHGEFPCD_02169	5.17e-220	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MHGEFPCD_02170	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MHGEFPCD_02171	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHGEFPCD_02172	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MHGEFPCD_02173	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHGEFPCD_02174	4.12e-168	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_02175	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MHGEFPCD_02176	4.31e-166	yodH	-	-	Q	-	-	-	Methyltransferase
MHGEFPCD_02177	6.87e-50	yodI	-	-	-	-	-	-	-
MHGEFPCD_02178	4.49e-192	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MHGEFPCD_02179	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MHGEFPCD_02181	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
MHGEFPCD_02182	5.04e-132	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MHGEFPCD_02183	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
MHGEFPCD_02185	7.75e-161	yodN	-	-	-	-	-	-	-
MHGEFPCD_02186	1.41e-16	-	-	-	E	-	-	-	lactoylglutathione lyase activity
MHGEFPCD_02187	1e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MHGEFPCD_02188	8.43e-64	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MHGEFPCD_02189	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MHGEFPCD_02190	3.44e-204	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MHGEFPCD_02191	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MHGEFPCD_02192	4.45e-158	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHGEFPCD_02193	6.87e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHGEFPCD_02194	3.41e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHGEFPCD_02195	3.4e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
MHGEFPCD_02197	5.71e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MHGEFPCD_02198	9.83e-317	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MHGEFPCD_02199	8.14e-63	cgeC	-	-	-	ko:K06321	-	ko00000	-
MHGEFPCD_02200	1.73e-87	cgeA	-	-	-	ko:K06319	-	ko00000	-
MHGEFPCD_02201	5.23e-230	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MHGEFPCD_02202	1.76e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MHGEFPCD_02203	7.81e-156	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MHGEFPCD_02204	2.2e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MHGEFPCD_02205	1.2e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHGEFPCD_02206	3.35e-89	ypoP	-	-	K	-	-	-	transcriptional
MHGEFPCD_02207	5.59e-126	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_02208	2.58e-176	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MHGEFPCD_02209	1.21e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHGEFPCD_02210	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MHGEFPCD_02211	4.25e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHGEFPCD_02212	3e-226	yplP	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02213	3.69e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MHGEFPCD_02214	6.97e-150	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHGEFPCD_02215	5.2e-118	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHGEFPCD_02216	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHGEFPCD_02217	6.48e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MHGEFPCD_02218	2.46e-172	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MHGEFPCD_02219	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MHGEFPCD_02220	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MHGEFPCD_02221	1.56e-201	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MHGEFPCD_02222	7.66e-127	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MHGEFPCD_02223	6.52e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MHGEFPCD_02224	6.6e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHGEFPCD_02225	1.82e-275	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MHGEFPCD_02226	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MHGEFPCD_02227	1.27e-17	degR	-	-	-	-	-	-	-
MHGEFPCD_02228	6.52e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MHGEFPCD_02229	6.59e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
MHGEFPCD_02230	2.06e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MHGEFPCD_02231	2.79e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHGEFPCD_02232	1.22e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MHGEFPCD_02234	3.33e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
MHGEFPCD_02235	4.92e-10	-	-	-	-	-	-	-	-
MHGEFPCD_02236	7.03e-53	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MHGEFPCD_02237	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MHGEFPCD_02238	3.46e-115	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MHGEFPCD_02239	1.26e-268	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MHGEFPCD_02240	1.07e-137	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHGEFPCD_02241	6.1e-64	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
MHGEFPCD_02242	8.58e-09	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MHGEFPCD_02243	2.03e-128	yrdC	-	-	Q	-	-	-	Isochorismatase family
MHGEFPCD_02244	6.6e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
MHGEFPCD_02245	1.35e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHGEFPCD_02246	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHGEFPCD_02247	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MHGEFPCD_02249	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
MHGEFPCD_02250	5.46e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MHGEFPCD_02251	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHGEFPCD_02252	1.09e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MHGEFPCD_02253	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MHGEFPCD_02255	1.64e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MHGEFPCD_02256	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHGEFPCD_02257	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MHGEFPCD_02258	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHGEFPCD_02259	9.16e-75	yppG	-	-	S	-	-	-	YppG-like protein
MHGEFPCD_02263	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
MHGEFPCD_02264	6.7e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MHGEFPCD_02265	6.98e-143	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHGEFPCD_02266	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHGEFPCD_02267	1.04e-118	ypoC	-	-	-	-	-	-	-
MHGEFPCD_02268	2.93e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHGEFPCD_02269	3.42e-167	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MHGEFPCD_02270	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MHGEFPCD_02271	1.46e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MHGEFPCD_02272	3.93e-104	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_02273	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MHGEFPCD_02274	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MHGEFPCD_02275	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHGEFPCD_02276	3.44e-203	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHGEFPCD_02277	1.14e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHGEFPCD_02278	1.5e-228	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHGEFPCD_02279	8.77e-282	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHGEFPCD_02280	3.63e-269	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHGEFPCD_02281	2.59e-169	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MHGEFPCD_02282	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MHGEFPCD_02283	9.78e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHGEFPCD_02284	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MHGEFPCD_02285	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHGEFPCD_02286	9.57e-288	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MHGEFPCD_02287	9.73e-181	ypjB	-	-	S	-	-	-	sporulation protein
MHGEFPCD_02288	1.2e-132	ypjA	-	-	S	-	-	-	membrane
MHGEFPCD_02289	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MHGEFPCD_02290	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MHGEFPCD_02291	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MHGEFPCD_02292	7.88e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MHGEFPCD_02293	2.6e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MHGEFPCD_02294	7.49e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MHGEFPCD_02295	1.35e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHGEFPCD_02296	8.4e-259	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MHGEFPCD_02297	1.44e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHGEFPCD_02298	4.65e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHGEFPCD_02299	1.73e-290	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHGEFPCD_02300	2.13e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MHGEFPCD_02301	4.08e-168	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MHGEFPCD_02302	2.37e-211	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHGEFPCD_02303	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHGEFPCD_02304	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHGEFPCD_02305	9.09e-260	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHGEFPCD_02306	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHGEFPCD_02307	3.32e-180	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MHGEFPCD_02308	8.53e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHGEFPCD_02309	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHGEFPCD_02310	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHGEFPCD_02311	1.33e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHGEFPCD_02312	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHGEFPCD_02313	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MHGEFPCD_02314	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHGEFPCD_02315	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHGEFPCD_02316	6.87e-173	yphF	-	-	-	-	-	-	-
MHGEFPCD_02317	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MHGEFPCD_02318	1.41e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MHGEFPCD_02319	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MHGEFPCD_02320	1.46e-134	yphA	-	-	-	-	-	-	-
MHGEFPCD_02321	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
MHGEFPCD_02322	1.33e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHGEFPCD_02323	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MHGEFPCD_02324	1.94e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MHGEFPCD_02325	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MHGEFPCD_02326	5e-79	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MHGEFPCD_02327	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MHGEFPCD_02328	3.77e-213	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MHGEFPCD_02329	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MHGEFPCD_02330	5.3e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MHGEFPCD_02331	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHGEFPCD_02332	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHGEFPCD_02333	1.9e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MHGEFPCD_02334	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MHGEFPCD_02335	5.85e-124	ypbE	-	-	M	-	-	-	Lysin motif
MHGEFPCD_02336	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MHGEFPCD_02337	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHGEFPCD_02338	3.37e-250	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MHGEFPCD_02339	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MHGEFPCD_02340	2.16e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHGEFPCD_02341	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHGEFPCD_02342	9.73e-255	rsiX	-	-	-	-	-	-	-
MHGEFPCD_02343	2.64e-134	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHGEFPCD_02344	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_02345	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_02346	3.6e-251	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHGEFPCD_02347	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MHGEFPCD_02348	1.02e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHGEFPCD_02349	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHGEFPCD_02350	1.05e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MHGEFPCD_02351	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MHGEFPCD_02352	4.63e-275	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHGEFPCD_02353	6.14e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MHGEFPCD_02354	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHGEFPCD_02355	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHGEFPCD_02357	2.33e-120	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MHGEFPCD_02358	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHGEFPCD_02359	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHGEFPCD_02360	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHGEFPCD_02361	3.97e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MHGEFPCD_02362	3.76e-268	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHGEFPCD_02363	2.01e-70	ypuD	-	-	-	-	-	-	-
MHGEFPCD_02364	8.95e-129	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHGEFPCD_02365	4.76e-106	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
MHGEFPCD_02366	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHGEFPCD_02367	6.31e-199	ypuA	-	-	S	-	-	-	Secreted protein
MHGEFPCD_02368	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHGEFPCD_02369	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MHGEFPCD_02370	5.32e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MHGEFPCD_02371	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MHGEFPCD_02372	3.34e-243	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MHGEFPCD_02373	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MHGEFPCD_02374	1.43e-78	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MHGEFPCD_02375	6.68e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MHGEFPCD_02376	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_02377	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHGEFPCD_02378	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MHGEFPCD_02379	1.43e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHGEFPCD_02380	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MHGEFPCD_02381	4.97e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHGEFPCD_02382	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MHGEFPCD_02383	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MHGEFPCD_02384	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MHGEFPCD_02385	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHGEFPCD_02386	4.38e-47	yqkK	-	-	-	-	-	-	-
MHGEFPCD_02387	1.96e-30	-	-	-	-	-	-	-	-
MHGEFPCD_02388	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MHGEFPCD_02389	2.4e-311	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MHGEFPCD_02390	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MHGEFPCD_02391	1.3e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MHGEFPCD_02392	1.9e-74	ansR	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02393	5.91e-280	yqxK	-	-	L	-	-	-	DNA helicase
MHGEFPCD_02394	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MHGEFPCD_02395	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MHGEFPCD_02396	4.4e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MHGEFPCD_02397	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MHGEFPCD_02398	4.77e-225	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MHGEFPCD_02399	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MHGEFPCD_02400	2.2e-79	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MHGEFPCD_02401	2.05e-223	yqkA	-	-	K	-	-	-	GrpB protein
MHGEFPCD_02402	5.96e-81	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MHGEFPCD_02403	2.81e-115	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MHGEFPCD_02404	2.31e-299	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHGEFPCD_02405	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
MHGEFPCD_02407	2.78e-236	yueF	-	-	S	-	-	-	transporter activity
MHGEFPCD_02409	5.43e-92	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGEFPCD_02410	5.2e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MHGEFPCD_02411	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MHGEFPCD_02412	2.39e-180	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_02413	7.63e-221	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHGEFPCD_02414	4.1e-187	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHGEFPCD_02415	5.64e-174	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MHGEFPCD_02416	9.58e-307	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MHGEFPCD_02417	5.69e-281	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHGEFPCD_02418	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHGEFPCD_02419	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_02420	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_02421	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_02422	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_02423	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_02424	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHGEFPCD_02425	1.32e-166	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MHGEFPCD_02426	3.89e-314	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHGEFPCD_02429	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHGEFPCD_02430	4.32e-122	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MHGEFPCD_02431	1.36e-212	-	-	-	K	-	-	-	LysR substrate binding domain
MHGEFPCD_02432	1.58e-66	-	-	-	S	-	-	-	GlpM protein
MHGEFPCD_02433	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHGEFPCD_02434	9.1e-189	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHGEFPCD_02435	1.95e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHGEFPCD_02436	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHGEFPCD_02437	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHGEFPCD_02438	4.71e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHGEFPCD_02439	2.63e-34	yqzJ	-	-	-	-	-	-	-
MHGEFPCD_02440	1.18e-190	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHGEFPCD_02441	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MHGEFPCD_02442	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHGEFPCD_02443	1.33e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MHGEFPCD_02445	2.61e-123	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_02446	6.5e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MHGEFPCD_02447	6.07e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHGEFPCD_02448	1.04e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MHGEFPCD_02449	3.37e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHGEFPCD_02450	4.83e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MHGEFPCD_02451	4.97e-218	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHGEFPCD_02452	1.31e-286	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHGEFPCD_02453	1.4e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHGEFPCD_02454	7.89e-222	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHGEFPCD_02455	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHGEFPCD_02456	1.2e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MHGEFPCD_02457	2.61e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHGEFPCD_02458	6.8e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MHGEFPCD_02459	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MHGEFPCD_02460	3.62e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MHGEFPCD_02461	3.84e-203	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHGEFPCD_02462	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MHGEFPCD_02463	7.23e-263	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MHGEFPCD_02464	1.07e-261	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MHGEFPCD_02465	4.65e-195	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MHGEFPCD_02466	3.24e-271	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MHGEFPCD_02467	1.56e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MHGEFPCD_02468	6.87e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MHGEFPCD_02470	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHGEFPCD_02471	1.15e-145	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
MHGEFPCD_02473	4.59e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHGEFPCD_02476	1.23e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHGEFPCD_02477	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHGEFPCD_02478	1.79e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MHGEFPCD_02479	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MHGEFPCD_02480	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MHGEFPCD_02481	1.02e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MHGEFPCD_02482	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHGEFPCD_02483	1.11e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHGEFPCD_02484	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHGEFPCD_02485	1.43e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHGEFPCD_02486	3.05e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHGEFPCD_02487	8.98e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHGEFPCD_02488	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_02489	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHGEFPCD_02490	4.67e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHGEFPCD_02491	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MHGEFPCD_02492	9.98e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MHGEFPCD_02493	1.05e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MHGEFPCD_02494	2.13e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MHGEFPCD_02495	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MHGEFPCD_02496	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MHGEFPCD_02497	1.7e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MHGEFPCD_02498	3.12e-221	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MHGEFPCD_02499	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MHGEFPCD_02500	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHGEFPCD_02501	4.96e-248	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MHGEFPCD_02502	5.66e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MHGEFPCD_02503	2.98e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MHGEFPCD_02504	7.65e-83	yqhP	-	-	-	-	-	-	-
MHGEFPCD_02505	2.85e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MHGEFPCD_02506	1.62e-96	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHGEFPCD_02507	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHGEFPCD_02508	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MHGEFPCD_02509	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHGEFPCD_02510	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHGEFPCD_02511	4.52e-262	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MHGEFPCD_02512	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHGEFPCD_02513	5.29e-196	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MHGEFPCD_02514	1.11e-30	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MHGEFPCD_02515	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MHGEFPCD_02516	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MHGEFPCD_02517	3.27e-103	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MHGEFPCD_02518	6.62e-156	yqxM	-	-	-	ko:K19433	-	ko00000	-
MHGEFPCD_02519	1.69e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MHGEFPCD_02520	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
MHGEFPCD_02521	4.03e-82	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MHGEFPCD_02522	1.9e-86	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MHGEFPCD_02523	2.21e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MHGEFPCD_02524	1.32e-92	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
MHGEFPCD_02525	5.22e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MHGEFPCD_02526	1.97e-234	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MHGEFPCD_02527	5.46e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHGEFPCD_02528	2.62e-238	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MHGEFPCD_02529	9.23e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHGEFPCD_02530	2.91e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHGEFPCD_02532	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MHGEFPCD_02533	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MHGEFPCD_02534	2e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MHGEFPCD_02535	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MHGEFPCD_02536	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
MHGEFPCD_02537	7.35e-254	yqgU	-	-	-	-	-	-	-
MHGEFPCD_02538	9.8e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MHGEFPCD_02539	2.91e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MHGEFPCD_02540	1.3e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MHGEFPCD_02541	1.88e-11	yqgO	-	-	-	-	-	-	-
MHGEFPCD_02542	2.57e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHGEFPCD_02543	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MHGEFPCD_02544	3.42e-68	yqzD	-	-	-	-	-	-	-
MHGEFPCD_02545	2.4e-97	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHGEFPCD_02546	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHGEFPCD_02547	8.33e-186	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHGEFPCD_02548	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MHGEFPCD_02549	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MHGEFPCD_02550	2.72e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MHGEFPCD_02551	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MHGEFPCD_02552	2.37e-289	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MHGEFPCD_02553	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MHGEFPCD_02554	2.76e-99	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MHGEFPCD_02555	1.08e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MHGEFPCD_02556	1.06e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MHGEFPCD_02557	1.39e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHGEFPCD_02558	3.34e-80	yqfX	-	-	S	-	-	-	membrane
MHGEFPCD_02559	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MHGEFPCD_02560	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MHGEFPCD_02561	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHGEFPCD_02562	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MHGEFPCD_02563	1.72e-213	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHGEFPCD_02564	3e-308	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHGEFPCD_02565	7.91e-87	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MHGEFPCD_02566	2.9e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHGEFPCD_02567	1.79e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHGEFPCD_02568	1.72e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MHGEFPCD_02569	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MHGEFPCD_02570	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHGEFPCD_02571	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHGEFPCD_02572	1.36e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MHGEFPCD_02573	1.29e-190	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHGEFPCD_02574	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
MHGEFPCD_02575	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MHGEFPCD_02576	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MHGEFPCD_02577	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MHGEFPCD_02578	6e-24	-	-	-	S	-	-	-	YqzL-like protein
MHGEFPCD_02579	1.16e-213	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHGEFPCD_02580	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHGEFPCD_02581	5.28e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MHGEFPCD_02582	1.44e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHGEFPCD_02583	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MHGEFPCD_02584	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MHGEFPCD_02585	2.15e-281	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MHGEFPCD_02586	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MHGEFPCD_02587	2.97e-84	yqfB	-	-	-	-	-	-	-
MHGEFPCD_02588	4.78e-177	yqfA	-	-	S	-	-	-	UPF0365 protein
MHGEFPCD_02589	3.83e-295	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MHGEFPCD_02590	3.19e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MHGEFPCD_02591	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MHGEFPCD_02592	2.38e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MHGEFPCD_02593	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MHGEFPCD_02594	1.75e-181	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHGEFPCD_02595	1.55e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MHGEFPCD_02596	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHGEFPCD_02597	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MHGEFPCD_02598	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHGEFPCD_02599	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHGEFPCD_02600	2.04e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MHGEFPCD_02601	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHGEFPCD_02602	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MHGEFPCD_02603	9.09e-280	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MHGEFPCD_02604	8.4e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHGEFPCD_02605	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MHGEFPCD_02606	3.84e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MHGEFPCD_02607	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MHGEFPCD_02608	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MHGEFPCD_02609	6.9e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MHGEFPCD_02610	2.3e-190	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHGEFPCD_02611	3.42e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
MHGEFPCD_02612	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHGEFPCD_02613	2.38e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MHGEFPCD_02614	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHGEFPCD_02615	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MHGEFPCD_02616	2.95e-201	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHGEFPCD_02617	1.13e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHGEFPCD_02618	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MHGEFPCD_02620	7.24e-178	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MHGEFPCD_02621	9.45e-180	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MHGEFPCD_02622	7.37e-48	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MHGEFPCD_02623	4.46e-277	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MHGEFPCD_02624	1.54e-73	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_02625	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
MHGEFPCD_02626	2.01e-273	-	-	-	D	-	-	-	nuclear chromosome segregation
MHGEFPCD_02627	7.01e-81	-	-	-	S	-	-	-	SMI1 / KNR4 family
MHGEFPCD_02628	9.34e-78	-	-	-	S	-	-	-	DNase/tRNase domain of colicin-like bacteriocin
MHGEFPCD_02630	2.33e-128	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHGEFPCD_02631	1.04e-112	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MHGEFPCD_02632	5.27e-253	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MHGEFPCD_02633	4.54e-15	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MHGEFPCD_02634	1.38e-165	-	-	-	L	-	-	-	helicase
MHGEFPCD_02636	4.64e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MHGEFPCD_02637	8.03e-87	-	-	-	S	-	-	-	Bacteriophage holin family
MHGEFPCD_02638	9.42e-202	xepA	-	-	-	-	-	-	-
MHGEFPCD_02639	6.71e-24	xkdX	-	-	-	-	-	-	-
MHGEFPCD_02640	2.74e-51	xkdW	-	-	S	-	-	-	XkdW protein
MHGEFPCD_02641	2.4e-190	-	-	-	-	-	-	-	-
MHGEFPCD_02642	4.8e-51	-	-	-	-	-	-	-	-
MHGEFPCD_02643	1.16e-127	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MHGEFPCD_02644	9.89e-241	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHGEFPCD_02645	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MHGEFPCD_02646	9.93e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MHGEFPCD_02647	6.31e-226	xkdQ	-	-	G	-	-	-	NLP P60 protein
MHGEFPCD_02648	1.54e-154	xkdP	-	-	S	-	-	-	Lysin motif
MHGEFPCD_02649	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MHGEFPCD_02650	8.03e-19	-	-	-	-	-	-	-	-
MHGEFPCD_02651	5.51e-89	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MHGEFPCD_02652	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
MHGEFPCD_02653	3.68e-298	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MHGEFPCD_02654	1.21e-34	-	-	-	-	-	-	-	-
MHGEFPCD_02655	1.43e-96	yqbJ	-	-	-	-	-	-	-
MHGEFPCD_02656	9.21e-115	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MHGEFPCD_02657	9.68e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MHGEFPCD_02658	4.8e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MHGEFPCD_02659	1.09e-62	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
MHGEFPCD_02660	2.95e-212	xkdG	-	-	S	-	-	-	Phage capsid family
MHGEFPCD_02661	1.48e-158	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
MHGEFPCD_02663	1.85e-180	-	-	-	S	-	-	-	Phage Mu protein F like protein
MHGEFPCD_02664	0.0	yqbA	-	-	S	-	-	-	portal protein
MHGEFPCD_02665	6.6e-313	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MHGEFPCD_02666	5.91e-135	yqaS	-	-	L	-	-	-	DNA packaging
MHGEFPCD_02668	1.58e-96	yqaQ	-	-	L	-	-	-	Transposase
MHGEFPCD_02669	3.14e-58	-	-	-	D	-	-	-	nuclear chromosome segregation
MHGEFPCD_02670	5.5e-41	-	-	-	-	-	-	-	-
MHGEFPCD_02671	7.15e-43	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MHGEFPCD_02672	4.28e-92	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MHGEFPCD_02674	1.33e-225	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MHGEFPCD_02675	5.62e-192	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MHGEFPCD_02676	5.34e-219	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MHGEFPCD_02677	2.05e-07	-	-	-	S	-	-	-	Hypothetical protein Yqai
MHGEFPCD_02680	1.73e-132	-	-	-	-	-	-	-	-
MHGEFPCD_02682	2.94e-24	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MHGEFPCD_02683	1.88e-42	-	-	-	K	-	-	-	sequence-specific DNA binding
MHGEFPCD_02684	1.11e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MHGEFPCD_02685	7.88e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHGEFPCD_02686	5.09e-202	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MHGEFPCD_02687	2.71e-120	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MHGEFPCD_02688	6.02e-190	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MHGEFPCD_02689	1.27e-132	ywqM	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02690	7.42e-159	-	-	-	E	-	-	-	amino acid
MHGEFPCD_02691	1.84e-91	psiE	-	-	S	ko:K13256	-	ko00000	Belongs to the PsiE family
MHGEFPCD_02692	5.51e-301	yrkQ	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_02693	4.64e-160	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MHGEFPCD_02694	1.7e-279	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MHGEFPCD_02695	3.41e-132	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MHGEFPCD_02696	1.29e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
MHGEFPCD_02697	5.75e-38	-	-	-	K	-	-	-	acetyltransferase
MHGEFPCD_02698	1.38e-282	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_02699	1.23e-103	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MHGEFPCD_02700	1.37e-120	-	-	-	S	-	-	-	DinB family
MHGEFPCD_02702	1.19e-189	supH	-	-	S	-	-	-	hydrolase
MHGEFPCD_02703	1.61e-184	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHGEFPCD_02704	2.9e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MHGEFPCD_02705	2.95e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHGEFPCD_02706	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_02707	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MHGEFPCD_02708	6.62e-231	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
MHGEFPCD_02709	1.96e-108	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHGEFPCD_02710	7.57e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02711	2.54e-268	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_02712	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MHGEFPCD_02713	5.56e-129	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MHGEFPCD_02714	9.01e-121	yrhH	-	-	Q	-	-	-	methyltransferase
MHGEFPCD_02715	4.8e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MHGEFPCD_02716	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MHGEFPCD_02717	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MHGEFPCD_02718	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MHGEFPCD_02719	3.91e-105	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MHGEFPCD_02720	3.31e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
MHGEFPCD_02721	1.53e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHGEFPCD_02722	7.96e-219	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MHGEFPCD_02723	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHGEFPCD_02724	2.94e-154	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHGEFPCD_02725	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MHGEFPCD_02726	2.92e-123	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MHGEFPCD_02727	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MHGEFPCD_02728	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHGEFPCD_02729	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MHGEFPCD_02730	5.4e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MHGEFPCD_02731	2.2e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MHGEFPCD_02732	1.91e-152	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MHGEFPCD_02733	4.91e-244	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHGEFPCD_02734	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MHGEFPCD_02735	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHGEFPCD_02736	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MHGEFPCD_02737	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHGEFPCD_02738	3.29e-237	yrrI	-	-	S	-	-	-	AI-2E family transporter
MHGEFPCD_02739	1.28e-167	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHGEFPCD_02740	1.28e-188	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHGEFPCD_02741	1.38e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHGEFPCD_02742	1.87e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHGEFPCD_02743	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MHGEFPCD_02744	8.4e-42	yrzR	-	-	-	-	-	-	-
MHGEFPCD_02745	7.16e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_02746	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHGEFPCD_02747	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MHGEFPCD_02748	3.55e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHGEFPCD_02749	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MHGEFPCD_02750	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_02751	8.81e-302	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHGEFPCD_02752	4.82e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHGEFPCD_02753	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHGEFPCD_02754	8.26e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MHGEFPCD_02757	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MHGEFPCD_02758	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHGEFPCD_02759	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHGEFPCD_02760	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHGEFPCD_02761	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MHGEFPCD_02762	2.23e-62	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MHGEFPCD_02763	2.55e-111	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MHGEFPCD_02764	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHGEFPCD_02765	1.41e-67	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MHGEFPCD_02766	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHGEFPCD_02767	8.28e-143	yrbG	-	-	S	-	-	-	membrane
MHGEFPCD_02768	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MHGEFPCD_02769	2.09e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MHGEFPCD_02770	8.2e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHGEFPCD_02771	4.75e-245	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHGEFPCD_02772	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MHGEFPCD_02773	1.02e-235	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHGEFPCD_02774	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHGEFPCD_02775	1.03e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MHGEFPCD_02777	1.79e-60	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHGEFPCD_02778	3.28e-252	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MHGEFPCD_02779	3.75e-266	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHGEFPCD_02780	1.83e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MHGEFPCD_02781	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MHGEFPCD_02782	8.12e-285	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MHGEFPCD_02783	2.49e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MHGEFPCD_02784	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MHGEFPCD_02785	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MHGEFPCD_02786	7.1e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHGEFPCD_02787	6.04e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MHGEFPCD_02788	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MHGEFPCD_02789	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MHGEFPCD_02790	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MHGEFPCD_02791	7.25e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MHGEFPCD_02792	4.65e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MHGEFPCD_02793	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MHGEFPCD_02794	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHGEFPCD_02795	1.76e-110	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MHGEFPCD_02796	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MHGEFPCD_02797	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MHGEFPCD_02798	2.5e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MHGEFPCD_02799	1e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MHGEFPCD_02800	1.54e-209	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MHGEFPCD_02801	1.81e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHGEFPCD_02802	6.26e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MHGEFPCD_02803	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHGEFPCD_02804	1.53e-35	-	-	-	-	-	-	-	-
MHGEFPCD_02805	7.7e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHGEFPCD_02806	2.4e-298	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MHGEFPCD_02807	3.8e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MHGEFPCD_02808	1.2e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MHGEFPCD_02809	3.98e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MHGEFPCD_02810	2.57e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHGEFPCD_02811	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MHGEFPCD_02812	4.36e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHGEFPCD_02813	3.93e-114	ysxD	-	-	-	-	-	-	-
MHGEFPCD_02814	3.1e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MHGEFPCD_02815	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHGEFPCD_02816	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MHGEFPCD_02817	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHGEFPCD_02818	3.16e-280	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHGEFPCD_02819	7.83e-240	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MHGEFPCD_02820	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHGEFPCD_02821	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHGEFPCD_02822	3.53e-254	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHGEFPCD_02823	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHGEFPCD_02824	1.12e-243	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHGEFPCD_02825	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MHGEFPCD_02826	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MHGEFPCD_02829	1.2e-54	res	-	-	L	-	-	-	Resolvase, N terminal domain
MHGEFPCD_02830	6.37e-17	res	-	-	L	-	-	-	Resolvase, N terminal domain
MHGEFPCD_02831	9.21e-115	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
MHGEFPCD_02832	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
MHGEFPCD_02833	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MHGEFPCD_02835	4.15e-71	-	-	-	L	-	-	-	Phage integrase family
MHGEFPCD_02838	1.85e-115	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MHGEFPCD_02839	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHGEFPCD_02840	1.44e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHGEFPCD_02841	4.47e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MHGEFPCD_02842	4.68e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MHGEFPCD_02843	2.18e-96	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHGEFPCD_02844	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_02845	2.67e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MHGEFPCD_02846	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MHGEFPCD_02847	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MHGEFPCD_02848	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MHGEFPCD_02849	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MHGEFPCD_02850	2.88e-273	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHGEFPCD_02851	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHGEFPCD_02852	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MHGEFPCD_02853	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MHGEFPCD_02854	1.67e-225	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MHGEFPCD_02855	5e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MHGEFPCD_02856	3.52e-178	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MHGEFPCD_02857	6.22e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_02858	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHGEFPCD_02859	3.03e-157	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MHGEFPCD_02860	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MHGEFPCD_02861	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHGEFPCD_02862	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MHGEFPCD_02863	2.87e-107	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MHGEFPCD_02864	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHGEFPCD_02865	1.53e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHGEFPCD_02866	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHGEFPCD_02867	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHGEFPCD_02868	1.89e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHGEFPCD_02869	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MHGEFPCD_02870	4.17e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MHGEFPCD_02871	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
MHGEFPCD_02872	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MHGEFPCD_02873	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MHGEFPCD_02874	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MHGEFPCD_02875	1.38e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MHGEFPCD_02876	1.78e-214	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MHGEFPCD_02877	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MHGEFPCD_02878	7.5e-282	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MHGEFPCD_02879	3.06e-181	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MHGEFPCD_02880	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHGEFPCD_02881	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MHGEFPCD_02882	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MHGEFPCD_02883	2.84e-240	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MHGEFPCD_02884	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MHGEFPCD_02885	6.58e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MHGEFPCD_02886	1.34e-56	ysdA	-	-	S	-	-	-	Membrane
MHGEFPCD_02887	2.3e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHGEFPCD_02888	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MHGEFPCD_02889	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHGEFPCD_02890	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHGEFPCD_02891	1.12e-68	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
MHGEFPCD_02892	4.27e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MHGEFPCD_02893	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_02894	2.94e-193	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MHGEFPCD_02895	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHGEFPCD_02896	2.32e-196	ytxC	-	-	S	-	-	-	YtxC-like family
MHGEFPCD_02897	8.99e-140	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MHGEFPCD_02898	1.42e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MHGEFPCD_02899	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MHGEFPCD_02900	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHGEFPCD_02901	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MHGEFPCD_02902	8.93e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHGEFPCD_02903	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02904	3.96e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MHGEFPCD_02905	2.16e-203	ytbE	-	-	S	-	-	-	reductase
MHGEFPCD_02906	3.43e-127	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHGEFPCD_02907	8.15e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHGEFPCD_02908	9.87e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHGEFPCD_02909	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHGEFPCD_02910	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MHGEFPCD_02911	4.82e-166	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_02912	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MHGEFPCD_02913	5.36e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MHGEFPCD_02914	1.42e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MHGEFPCD_02915	3.79e-132	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHGEFPCD_02916	9.1e-178	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MHGEFPCD_02918	4.52e-82	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MHGEFPCD_02919	5.65e-96	ytwI	-	-	S	-	-	-	membrane
MHGEFPCD_02920	1.41e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MHGEFPCD_02921	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MHGEFPCD_02922	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MHGEFPCD_02923	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHGEFPCD_02924	6.63e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHGEFPCD_02925	8.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHGEFPCD_02926	4.23e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MHGEFPCD_02927	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MHGEFPCD_02928	2.01e-74	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MHGEFPCD_02929	2.64e-114	ytrI	-	-	-	-	-	-	-
MHGEFPCD_02930	1e-31	-	-	-	-	-	-	-	-
MHGEFPCD_02931	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MHGEFPCD_02932	1.24e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
MHGEFPCD_02933	1.94e-304	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MHGEFPCD_02934	4.16e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MHGEFPCD_02935	3.41e-183	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_02937	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MHGEFPCD_02938	3.03e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHGEFPCD_02939	4.03e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MHGEFPCD_02940	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHGEFPCD_02941	3.41e-231	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MHGEFPCD_02942	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHGEFPCD_02943	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MHGEFPCD_02944	5.2e-156	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MHGEFPCD_02945	1.87e-112	yteJ	-	-	S	-	-	-	RDD family
MHGEFPCD_02946	6.39e-235	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MHGEFPCD_02947	9.45e-196	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHGEFPCD_02948	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MHGEFPCD_02949	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHGEFPCD_02950	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MHGEFPCD_02951	1.47e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHGEFPCD_02952	1.36e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MHGEFPCD_02953	3.95e-308	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MHGEFPCD_02954	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHGEFPCD_02955	3.58e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MHGEFPCD_02956	2.41e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02957	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MHGEFPCD_02958	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MHGEFPCD_02959	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHGEFPCD_02960	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHGEFPCD_02961	1.71e-86	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MHGEFPCD_02963	4.63e-110	-	-	-	L	-	-	-	DEAD-like helicases superfamily
MHGEFPCD_02964	1.08e-38	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MHGEFPCD_02965	1.79e-31	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MHGEFPCD_02966	4.02e-23	-	-	-	-	-	-	-	-
MHGEFPCD_02967	4.54e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHGEFPCD_02969	1.36e-117	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MHGEFPCD_02971	2.39e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MHGEFPCD_02972	7.09e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHGEFPCD_02973	7.76e-191	-	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_02974	4.95e-161	ygaZ	-	-	E	-	-	-	AzlC protein
MHGEFPCD_02975	3.06e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MHGEFPCD_02976	5.98e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHGEFPCD_02977	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHGEFPCD_02978	8.15e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHGEFPCD_02979	4.16e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MHGEFPCD_02980	3.35e-291	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MHGEFPCD_02981	1.05e-155	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MHGEFPCD_02982	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MHGEFPCD_02983	5.91e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MHGEFPCD_02984	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHGEFPCD_02985	5.9e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MHGEFPCD_02986	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MHGEFPCD_02987	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHGEFPCD_02988	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MHGEFPCD_02989	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MHGEFPCD_02990	2.43e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHGEFPCD_02991	1.69e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MHGEFPCD_02992	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
MHGEFPCD_02993	5.77e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MHGEFPCD_02994	5.06e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MHGEFPCD_02995	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
MHGEFPCD_02996	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MHGEFPCD_02997	3.75e-209	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHGEFPCD_02998	6.43e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHGEFPCD_02999	1.11e-59	ytzH	-	-	S	-	-	-	YtzH-like protein
MHGEFPCD_03000	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
MHGEFPCD_03001	6.57e-224	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MHGEFPCD_03002	9.95e-215	ytlQ	-	-	-	-	-	-	-
MHGEFPCD_03003	1.56e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHGEFPCD_03004	2.38e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MHGEFPCD_03005	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MHGEFPCD_03006	2.99e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHGEFPCD_03007	7.44e-278	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MHGEFPCD_03008	3.14e-164	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHGEFPCD_03009	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MHGEFPCD_03010	7.13e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHGEFPCD_03011	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHGEFPCD_03012	7.53e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MHGEFPCD_03013	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MHGEFPCD_03014	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MHGEFPCD_03015	5.5e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_03016	8.91e-308	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHGEFPCD_03017	3.77e-216	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHGEFPCD_03018	4.78e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHGEFPCD_03019	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MHGEFPCD_03020	8.39e-112	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
MHGEFPCD_03021	4.98e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MHGEFPCD_03022	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MHGEFPCD_03023	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MHGEFPCD_03024	5.91e-175	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MHGEFPCD_03025	2.36e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MHGEFPCD_03026	3.8e-163	ywaF	-	-	S	-	-	-	Integral membrane protein
MHGEFPCD_03027	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MHGEFPCD_03028	4.63e-174	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03029	1.18e-219	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MHGEFPCD_03030	2.6e-166	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_03031	4.54e-286	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MHGEFPCD_03032	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03033	3e-208	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MHGEFPCD_03034	1.02e-232	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHGEFPCD_03035	7.06e-224	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHGEFPCD_03036	5.11e-208	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03037	5.41e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MHGEFPCD_03038	7.09e-53	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MHGEFPCD_03039	6.73e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MHGEFPCD_03040	1.26e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MHGEFPCD_03042	2.12e-184	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
MHGEFPCD_03043	8.21e-271	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MHGEFPCD_03044	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MHGEFPCD_03045	3.33e-83	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHGEFPCD_03046	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHGEFPCD_03047	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHGEFPCD_03048	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHGEFPCD_03049	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHGEFPCD_03050	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MHGEFPCD_03051	1.29e-188	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHGEFPCD_03052	1.25e-236	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHGEFPCD_03053	7.14e-183	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHGEFPCD_03054	2.51e-172	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHGEFPCD_03055	1.01e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MHGEFPCD_03056	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MHGEFPCD_03057	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MHGEFPCD_03059	1.48e-99	ytkA	-	-	S	-	-	-	YtkA-like
MHGEFPCD_03060	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHGEFPCD_03061	8.41e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MHGEFPCD_03062	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MHGEFPCD_03063	7.13e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MHGEFPCD_03064	1.82e-312	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MHGEFPCD_03065	2.6e-235	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MHGEFPCD_03066	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MHGEFPCD_03067	1.23e-158	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MHGEFPCD_03068	5.94e-201	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHGEFPCD_03069	3.16e-156	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHGEFPCD_03070	3.57e-162	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MHGEFPCD_03071	1.37e-270	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHGEFPCD_03072	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHGEFPCD_03073	6.18e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHGEFPCD_03074	3.43e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHGEFPCD_03075	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHGEFPCD_03076	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MHGEFPCD_03077	3.03e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MHGEFPCD_03078	6.1e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MHGEFPCD_03100	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHGEFPCD_03101	5.96e-126	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MHGEFPCD_03102	6.2e-277	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MHGEFPCD_03103	3.24e-108	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MHGEFPCD_03104	1.21e-103	yuaE	-	-	S	-	-	-	DinB superfamily
MHGEFPCD_03105	3.23e-139	-	-	-	S	-	-	-	MOSC domain
MHGEFPCD_03106	4.99e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MHGEFPCD_03107	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHGEFPCD_03108	9.66e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MHGEFPCD_03109	3.78e-120	yuaB	-	-	-	-	-	-	-
MHGEFPCD_03110	3.04e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MHGEFPCD_03111	1.82e-191	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHGEFPCD_03112	1.03e-282	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHGEFPCD_03113	4.53e-158	-	-	-	G	-	-	-	Cupin
MHGEFPCD_03114	5.31e-69	yjcN	-	-	-	-	-	-	-
MHGEFPCD_03116	6.56e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHGEFPCD_03117	2.34e-249	yubA	-	-	S	-	-	-	transporter activity
MHGEFPCD_03118	1.35e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MHGEFPCD_03119	1.64e-125	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MHGEFPCD_03120	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHGEFPCD_03121	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHGEFPCD_03122	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHGEFPCD_03123	6.29e-316	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHGEFPCD_03124	1.82e-178	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MHGEFPCD_03125	9.36e-55	-	-	-	-	-	-	-	-
MHGEFPCD_03126	4.05e-242	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHGEFPCD_03127	2.14e-100	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MHGEFPCD_03128	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHGEFPCD_03129	1.63e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHGEFPCD_03130	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MHGEFPCD_03131	1.02e-21	-	-	-	-	-	-	-	-
MHGEFPCD_03132	4.93e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MHGEFPCD_03133	6.59e-229	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MHGEFPCD_03134	8.53e-95	yugN	-	-	S	-	-	-	YugN-like family
MHGEFPCD_03136	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MHGEFPCD_03137	1.32e-131	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MHGEFPCD_03138	4.34e-152	ycaC	-	-	Q	-	-	-	Isochorismatase family
MHGEFPCD_03139	1.37e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MHGEFPCD_03140	1.92e-285	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHGEFPCD_03141	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MHGEFPCD_03142	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MHGEFPCD_03143	9.69e-266	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MHGEFPCD_03144	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03145	5.72e-200	yugF	-	-	I	-	-	-	Hydrolase
MHGEFPCD_03146	1e-53	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MHGEFPCD_03147	4.53e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHGEFPCD_03148	7.38e-292	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_03149	6.62e-87	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MHGEFPCD_03150	5.9e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MHGEFPCD_03151	9.14e-264	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MHGEFPCD_03152	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MHGEFPCD_03153	2.62e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03154	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MHGEFPCD_03155	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MHGEFPCD_03156	5.63e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MHGEFPCD_03157	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MHGEFPCD_03158	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03159	4.5e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHGEFPCD_03160	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHGEFPCD_03162	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHGEFPCD_03163	6.3e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHGEFPCD_03164	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHGEFPCD_03165	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHGEFPCD_03166	2.38e-99	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHGEFPCD_03167	1.91e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHGEFPCD_03168	4.2e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MHGEFPCD_03169	4.86e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MHGEFPCD_03170	1.9e-146	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHGEFPCD_03171	8.11e-316	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_03173	7.66e-76	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MHGEFPCD_03174	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
MHGEFPCD_03175	2.18e-69	yuzC	-	-	-	-	-	-	-
MHGEFPCD_03176	3.97e-295	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MHGEFPCD_03177	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHGEFPCD_03178	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MHGEFPCD_03179	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MHGEFPCD_03180	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
MHGEFPCD_03181	2.13e-44	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MHGEFPCD_03182	3.78e-238	yueF	-	-	S	-	-	-	transporter activity
MHGEFPCD_03183	5.68e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MHGEFPCD_03184	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MHGEFPCD_03185	4.12e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_03186	1.55e-99	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MHGEFPCD_03187	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MHGEFPCD_03188	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHGEFPCD_03189	8.86e-273	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MHGEFPCD_03190	9.1e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MHGEFPCD_03191	2.36e-61	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MHGEFPCD_03192	1.49e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
MHGEFPCD_03193	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MHGEFPCD_03194	1.77e-170	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MHGEFPCD_03195	1.58e-45	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MHGEFPCD_03196	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_03197	4.1e-222	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MHGEFPCD_03198	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MHGEFPCD_03199	6.74e-287	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MHGEFPCD_03200	1.49e-172	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_03201	1.41e-208	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MHGEFPCD_03202	4.59e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MHGEFPCD_03203	1.52e-130	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MHGEFPCD_03204	2.35e-275	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MHGEFPCD_03205	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHGEFPCD_03206	4.99e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MHGEFPCD_03207	5.71e-152	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03208	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
MHGEFPCD_03209	3.42e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MHGEFPCD_03210	4.19e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MHGEFPCD_03212	2.72e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHGEFPCD_03213	4.68e-39	-	-	-	-	-	-	-	-
MHGEFPCD_03214	6.91e-92	-	-	-	CP	-	-	-	Membrane
MHGEFPCD_03215	1.32e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHGEFPCD_03217	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
MHGEFPCD_03219	1.62e-123	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MHGEFPCD_03220	9.01e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_03221	1.38e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MHGEFPCD_03222	2.25e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHGEFPCD_03223	1.49e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHGEFPCD_03224	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MHGEFPCD_03225	4.9e-265	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MHGEFPCD_03226	3.85e-72	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03227	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MHGEFPCD_03228	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MHGEFPCD_03229	1.94e-216	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHGEFPCD_03230	9.35e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHGEFPCD_03231	2.37e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MHGEFPCD_03232	1.04e-248	yutH	-	-	S	-	-	-	Spore coat protein
MHGEFPCD_03233	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MHGEFPCD_03234	5.87e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHGEFPCD_03235	2.2e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MHGEFPCD_03236	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03237	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHGEFPCD_03238	1.37e-249	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MHGEFPCD_03239	2.17e-164	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MHGEFPCD_03240	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHGEFPCD_03241	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHGEFPCD_03242	1.04e-216	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MHGEFPCD_03243	5.25e-81	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
MHGEFPCD_03244	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MHGEFPCD_03245	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MHGEFPCD_03246	3.32e-08	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MHGEFPCD_03248	4.57e-26	yqbA	-	-	S	-	-	-	portal protein
MHGEFPCD_03250	1.05e-274	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_03251	2.42e-301	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHGEFPCD_03252	1.63e-297	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHGEFPCD_03253	7.06e-218	bsn	-	-	L	-	-	-	Ribonuclease
MHGEFPCD_03254	1.07e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_03255	1.39e-171	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MHGEFPCD_03256	4.37e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MHGEFPCD_03257	8.84e-210	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MHGEFPCD_03258	5.26e-203	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHGEFPCD_03259	2.12e-312	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MHGEFPCD_03260	1.29e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MHGEFPCD_03261	5.28e-209	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHGEFPCD_03263	3.91e-95	-	-	-	-	-	-	-	-
MHGEFPCD_03264	4.94e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MHGEFPCD_03266	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MHGEFPCD_03267	1.29e-259	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MHGEFPCD_03268	2.32e-48	-	-	-	-	-	-	-	-
MHGEFPCD_03270	3.07e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MHGEFPCD_03271	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MHGEFPCD_03272	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MHGEFPCD_03273	6.62e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHGEFPCD_03274	5.01e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MHGEFPCD_03275	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHGEFPCD_03276	8.85e-85	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHGEFPCD_03277	3.66e-186	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MHGEFPCD_03278	1.46e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MHGEFPCD_03279	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHGEFPCD_03280	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MHGEFPCD_03281	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
MHGEFPCD_03282	1.08e-82	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MHGEFPCD_03283	1.27e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MHGEFPCD_03284	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHGEFPCD_03285	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MHGEFPCD_03286	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MHGEFPCD_03287	7.74e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MHGEFPCD_03288	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MHGEFPCD_03289	5.35e-215	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MHGEFPCD_03290	3.2e-58	-	-	-	-	-	-	-	-
MHGEFPCD_03291	2.58e-71	yusN	-	-	M	-	-	-	Coat F domain
MHGEFPCD_03292	9.65e-92	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MHGEFPCD_03293	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MHGEFPCD_03294	1.39e-202	-	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03295	1.38e-174	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MHGEFPCD_03296	6.46e-222	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHGEFPCD_03297	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MHGEFPCD_03298	9.06e-193	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHGEFPCD_03299	7.24e-58	-	-	-	S	-	-	-	YusW-like protein
MHGEFPCD_03300	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MHGEFPCD_03301	5.03e-193	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_03302	4.12e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MHGEFPCD_03303	1.47e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHGEFPCD_03304	3.7e-163	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_03305	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_03306	2.68e-32	-	-	-	-	-	-	-	-
MHGEFPCD_03307	9.81e-201	yuxN	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03308	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHGEFPCD_03309	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MHGEFPCD_03310	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MHGEFPCD_03311	5.31e-245	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MHGEFPCD_03312	9.16e-264	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MHGEFPCD_03313	1.19e-138	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHGEFPCD_03314	1.65e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_03315	8.92e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MHGEFPCD_03316	2.76e-190	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MHGEFPCD_03317	2.79e-133	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MHGEFPCD_03318	1.62e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MHGEFPCD_03319	7.93e-289	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_03320	5.36e-132	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MHGEFPCD_03321	1.72e-285	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MHGEFPCD_03322	5.37e-229	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_03323	1.16e-215	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHGEFPCD_03324	2.89e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_03325	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MHGEFPCD_03326	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_03327	2.7e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_03328	9.71e-50	-	-	-	-	-	-	-	-
MHGEFPCD_03329	1.87e-133	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MHGEFPCD_03330	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
MHGEFPCD_03331	3.11e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MHGEFPCD_03332	8.03e-87	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MHGEFPCD_03333	1.97e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHGEFPCD_03334	1.67e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_03335	3.29e-238	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_03336	5.22e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHGEFPCD_03337	5.89e-158	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MHGEFPCD_03338	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MHGEFPCD_03339	3.7e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MHGEFPCD_03340	1.01e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MHGEFPCD_03341	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MHGEFPCD_03342	9.94e-214	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MHGEFPCD_03343	5.58e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MHGEFPCD_03344	5.72e-127	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MHGEFPCD_03345	3.4e-145	yfiK	-	-	K	-	-	-	Regulator
MHGEFPCD_03346	1.74e-252	-	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_03347	1.66e-218	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MHGEFPCD_03348	8.22e-248	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MHGEFPCD_03349	2.02e-252	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MHGEFPCD_03350	1.77e-200	yvgN	-	-	S	-	-	-	reductase
MHGEFPCD_03351	1.38e-113	yvgO	-	-	-	-	-	-	-
MHGEFPCD_03352	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MHGEFPCD_03353	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHGEFPCD_03354	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHGEFPCD_03355	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHGEFPCD_03356	6.36e-130	yvgT	-	-	S	-	-	-	membrane
MHGEFPCD_03357	3.29e-191	-	-	-	S	-	-	-	Metallo-peptidase family M12
MHGEFPCD_03358	2.93e-93	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MHGEFPCD_03359	3.33e-140	bdbD	-	-	O	-	-	-	Thioredoxin
MHGEFPCD_03360	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MHGEFPCD_03361	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MHGEFPCD_03362	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
MHGEFPCD_03363	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MHGEFPCD_03364	2.88e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MHGEFPCD_03365	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHGEFPCD_03366	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_03367	2.39e-60	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MHGEFPCD_03368	2.91e-231	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_03369	1.23e-178	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHGEFPCD_03370	2.26e-153	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHGEFPCD_03371	2.97e-156	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHGEFPCD_03372	5.24e-190	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MHGEFPCD_03373	1.76e-169	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MHGEFPCD_03374	6.38e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MHGEFPCD_03375	6.6e-205	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MHGEFPCD_03376	1.6e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHGEFPCD_03377	9.07e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MHGEFPCD_03379	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHGEFPCD_03380	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHGEFPCD_03381	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MHGEFPCD_03382	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MHGEFPCD_03383	2.73e-46	yvzC	-	-	K	-	-	-	transcriptional
MHGEFPCD_03384	2.73e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MHGEFPCD_03385	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MHGEFPCD_03386	2.44e-69	yvaP	-	-	K	-	-	-	transcriptional
MHGEFPCD_03387	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MHGEFPCD_03388	5.26e-156	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MHGEFPCD_03389	4.95e-170	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHGEFPCD_03390	2.33e-155	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHGEFPCD_03391	1.27e-160	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03392	2.09e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHGEFPCD_03393	2.56e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHGEFPCD_03394	3.4e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHGEFPCD_03395	1.36e-266	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHGEFPCD_03396	9.8e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MHGEFPCD_03397	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHGEFPCD_03398	1.09e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHGEFPCD_03399	1.61e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHGEFPCD_03400	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHGEFPCD_03401	4.11e-129	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MHGEFPCD_03402	1.88e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MHGEFPCD_03403	5.14e-155	yvbI	-	-	M	-	-	-	Membrane
MHGEFPCD_03404	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MHGEFPCD_03405	1.38e-91	yvbK	-	-	K	-	-	-	acetyltransferase
MHGEFPCD_03406	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHGEFPCD_03407	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MHGEFPCD_03408	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHGEFPCD_03409	1.33e-275	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MHGEFPCD_03410	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHGEFPCD_03411	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHGEFPCD_03413	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHGEFPCD_03414	6.68e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MHGEFPCD_03415	5.33e-243	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_03416	9.16e-162	yvbU	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03417	5.22e-203	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MHGEFPCD_03418	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHGEFPCD_03420	3.67e-193	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
MHGEFPCD_03421	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MHGEFPCD_03422	1.31e-288	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MHGEFPCD_03423	5.86e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHGEFPCD_03424	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHGEFPCD_03425	3.55e-172	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHGEFPCD_03426	1.25e-281	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHGEFPCD_03427	2.55e-155	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MHGEFPCD_03428	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MHGEFPCD_03429	1.61e-309	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHGEFPCD_03430	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
MHGEFPCD_03431	2.61e-236	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MHGEFPCD_03432	4.51e-281	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MHGEFPCD_03433	4.67e-78	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MHGEFPCD_03434	1.11e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHGEFPCD_03435	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHGEFPCD_03436	1.05e-249	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHGEFPCD_03437	4.3e-256	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MHGEFPCD_03438	1.26e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MHGEFPCD_03439	1.71e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MHGEFPCD_03440	1.17e-270	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MHGEFPCD_03441	1.59e-205	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHGEFPCD_03442	1.75e-277	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MHGEFPCD_03443	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MHGEFPCD_03444	1.55e-151	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MHGEFPCD_03445	3.91e-154	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MHGEFPCD_03446	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MHGEFPCD_03447	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MHGEFPCD_03449	4.68e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MHGEFPCD_03450	1.06e-145	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MHGEFPCD_03451	3.29e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHGEFPCD_03452	1.01e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MHGEFPCD_03453	3.75e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MHGEFPCD_03455	1.13e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MHGEFPCD_03456	4.02e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MHGEFPCD_03458	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MHGEFPCD_03459	6.77e-48	-	-	-	-	-	-	-	-
MHGEFPCD_03461	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MHGEFPCD_03462	4.05e-285	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MHGEFPCD_03463	9.47e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MHGEFPCD_03464	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHGEFPCD_03465	5.45e-123	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHGEFPCD_03466	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHGEFPCD_03467	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MHGEFPCD_03468	3.94e-137	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MHGEFPCD_03469	2.62e-178	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MHGEFPCD_03470	3.14e-279	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MHGEFPCD_03471	1.9e-264	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MHGEFPCD_03472	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MHGEFPCD_03473	9.37e-207	yvdE	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03474	8.57e-134	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MHGEFPCD_03475	5.31e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MHGEFPCD_03476	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MHGEFPCD_03477	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MHGEFPCD_03478	1.02e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHGEFPCD_03479	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
MHGEFPCD_03480	6.92e-184	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MHGEFPCD_03481	2.76e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MHGEFPCD_03482	1.48e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MHGEFPCD_03483	1.28e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MHGEFPCD_03484	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MHGEFPCD_03485	5.15e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHGEFPCD_03486	3.13e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHGEFPCD_03487	4.72e-200	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MHGEFPCD_03488	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MHGEFPCD_03489	7.88e-245	sasA	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_03490	3.99e-158	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_03491	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MHGEFPCD_03492	4.7e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MHGEFPCD_03493	8e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHGEFPCD_03494	3.79e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHGEFPCD_03495	3.29e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHGEFPCD_03496	1.12e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MHGEFPCD_03497	4.51e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHGEFPCD_03498	1.83e-148	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHGEFPCD_03499	1.73e-269	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHGEFPCD_03500	2.93e-177	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MHGEFPCD_03501	4.35e-115	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MHGEFPCD_03502	2.72e-156	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHGEFPCD_03503	2.92e-192	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHGEFPCD_03504	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHGEFPCD_03505	7.85e-285	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHGEFPCD_03506	5.45e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHGEFPCD_03507	1.05e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MHGEFPCD_03508	8.92e-136	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MHGEFPCD_03509	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MHGEFPCD_03510	3.12e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MHGEFPCD_03511	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MHGEFPCD_03512	3.72e-217	yvlB	-	-	S	-	-	-	Putative adhesin
MHGEFPCD_03513	4.87e-66	yvlA	-	-	-	-	-	-	-
MHGEFPCD_03514	8.07e-44	yvkN	-	-	-	-	-	-	-
MHGEFPCD_03515	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHGEFPCD_03516	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHGEFPCD_03517	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03518	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MHGEFPCD_03519	5.48e-143	yvkB	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03520	3.99e-296	yvkA	-	-	P	-	-	-	-transporter
MHGEFPCD_03521	4.08e-34	-	-	-	Q	-	-	-	Thioesterase domain
MHGEFPCD_03523	2.5e-232	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MHGEFPCD_03524	3.33e-59	-	-	-	E	-	-	-	Saccharopine dehydrogenase
MHGEFPCD_03525	2.64e-117	-	-	-	V	-	-	-	ABC transporter transmembrane region
MHGEFPCD_03526	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
MHGEFPCD_03527	0.0	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
MHGEFPCD_03528	7.11e-82	-	-	-	IQ	-	-	-	KR domain
MHGEFPCD_03529	2.02e-19	-	-	-	L	ko:K07497	-	ko00000	transposition
MHGEFPCD_03530	1.7e-279	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHGEFPCD_03531	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MHGEFPCD_03532	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MHGEFPCD_03533	2.09e-305	ywoF	-	-	P	-	-	-	Right handed beta helix region
MHGEFPCD_03534	2.48e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHGEFPCD_03535	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MHGEFPCD_03536	3.08e-60	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MHGEFPCD_03537	7.99e-191	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHGEFPCD_03538	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHGEFPCD_03539	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHGEFPCD_03540	3.94e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHGEFPCD_03541	1.35e-89	-	-	-	-	-	-	-	-
MHGEFPCD_03542	7.78e-11	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MHGEFPCD_03543	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MHGEFPCD_03544	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHGEFPCD_03545	1.3e-152	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHGEFPCD_03546	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHGEFPCD_03547	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHGEFPCD_03548	9.36e-107	yviE	-	-	-	-	-	-	-
MHGEFPCD_03549	1.2e-208	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MHGEFPCD_03550	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MHGEFPCD_03551	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
MHGEFPCD_03552	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MHGEFPCD_03553	1.1e-97	yvyF	-	-	S	-	-	-	flagellar protein
MHGEFPCD_03554	5.83e-99	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MHGEFPCD_03555	3.56e-57	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MHGEFPCD_03556	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHGEFPCD_03557	8.81e-204	degV	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03558	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHGEFPCD_03559	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHGEFPCD_03560	2.94e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MHGEFPCD_03561	1.9e-230	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03562	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHGEFPCD_03563	5.45e-302	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MHGEFPCD_03564	2.82e-185	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MHGEFPCD_03565	6.04e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MHGEFPCD_03566	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MHGEFPCD_03567	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHGEFPCD_03568	5.08e-282	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MHGEFPCD_03569	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHGEFPCD_03570	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHGEFPCD_03571	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MHGEFPCD_03572	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MHGEFPCD_03573	7.59e-64	-	-	-	-	-	-	-	-
MHGEFPCD_03574	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHGEFPCD_03575	9.56e-266	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHGEFPCD_03576	2.64e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHGEFPCD_03577	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHGEFPCD_03578	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MHGEFPCD_03579	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHGEFPCD_03580	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MHGEFPCD_03581	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MHGEFPCD_03582	1.06e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHGEFPCD_03583	3.04e-278	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHGEFPCD_03584	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHGEFPCD_03585	7.21e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHGEFPCD_03586	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MHGEFPCD_03587	2.36e-249	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MHGEFPCD_03588	1.17e-269	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MHGEFPCD_03589	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
MHGEFPCD_03590	4.54e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHGEFPCD_03591	1.89e-228	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03592	8.76e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MHGEFPCD_03593	9.04e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MHGEFPCD_03594	2.62e-302	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHGEFPCD_03595	4.04e-29	ywtC	-	-	-	-	-	-	-
MHGEFPCD_03596	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MHGEFPCD_03597	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MHGEFPCD_03598	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MHGEFPCD_03599	4.41e-242	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MHGEFPCD_03600	1.08e-247	-	-	-	E	-	-	-	Spore germination protein
MHGEFPCD_03601	1.69e-258	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
MHGEFPCD_03602	3.01e-228	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MHGEFPCD_03603	8.41e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHGEFPCD_03604	2.78e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHGEFPCD_03605	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHGEFPCD_03606	5.37e-205	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHGEFPCD_03607	9.85e-208	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MHGEFPCD_03608	1.01e-116	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MHGEFPCD_03609	2.13e-124	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MHGEFPCD_03610	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MHGEFPCD_03611	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MHGEFPCD_03612	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
MHGEFPCD_03613	3.64e-307	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHGEFPCD_03614	3.43e-163	ywrJ	-	-	-	-	-	-	-
MHGEFPCD_03615	1.29e-185	cotB	-	-	-	ko:K06325	-	ko00000	-
MHGEFPCD_03616	2.27e-270	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MHGEFPCD_03617	1.64e-18	-	-	-	-	-	-	-	-
MHGEFPCD_03618	6.96e-145	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MHGEFPCD_03620	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MHGEFPCD_03621	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MHGEFPCD_03622	9.9e-131	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MHGEFPCD_03623	3.51e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MHGEFPCD_03625	3.13e-122	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
MHGEFPCD_03626	1.39e-201	-	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03627	3.72e-151	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MHGEFPCD_03629	1.36e-299	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MHGEFPCD_03630	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MHGEFPCD_03633	6.64e-189	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MHGEFPCD_03634	2.14e-314	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHGEFPCD_03635	1.23e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MHGEFPCD_03636	6.33e-157	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MHGEFPCD_03637	2.04e-151	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MHGEFPCD_03638	1.74e-21	-	-	-	-	-	-	-	-
MHGEFPCD_03639	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MHGEFPCD_03640	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHGEFPCD_03641	3.72e-202	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MHGEFPCD_03642	1.18e-181	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MHGEFPCD_03643	5.13e-77	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MHGEFPCD_03644	4.49e-82	ywpG	-	-	-	-	-	-	-
MHGEFPCD_03645	3.73e-90	ywpF	-	-	S	-	-	-	YwpF-like protein
MHGEFPCD_03646	1.53e-73	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHGEFPCD_03647	6.36e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHGEFPCD_03648	5.22e-255	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MHGEFPCD_03649	1.05e-184	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MHGEFPCD_03650	1.03e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MHGEFPCD_03651	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MHGEFPCD_03652	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MHGEFPCD_03653	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
MHGEFPCD_03654	4.1e-272	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHGEFPCD_03655	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MHGEFPCD_03656	2.31e-311	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MHGEFPCD_03657	5.6e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
MHGEFPCD_03658	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MHGEFPCD_03659	1.07e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MHGEFPCD_03660	3.47e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHGEFPCD_03661	8.23e-132	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MHGEFPCD_03662	1.29e-92	ywnJ	-	-	S	-	-	-	VanZ like family
MHGEFPCD_03663	2.65e-188	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MHGEFPCD_03664	2.76e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MHGEFPCD_03666	6.01e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MHGEFPCD_03667	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHGEFPCD_03668	1.33e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MHGEFPCD_03669	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MHGEFPCD_03670	7.29e-87	ywnA	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03671	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MHGEFPCD_03672	8.83e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MHGEFPCD_03673	1.94e-66	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MHGEFPCD_03674	8.42e-17	csbD	-	-	K	-	-	-	CsbD-like
MHGEFPCD_03675	1.05e-107	ywmF	-	-	S	-	-	-	Peptidase M50
MHGEFPCD_03676	1.93e-117	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MHGEFPCD_03677	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHGEFPCD_03678	1.01e-183	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHGEFPCD_03680	1.44e-156	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MHGEFPCD_03681	2.59e-160	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MHGEFPCD_03682	1.41e-242	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MHGEFPCD_03683	7.05e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHGEFPCD_03684	4.64e-172	ywmB	-	-	S	-	-	-	TATA-box binding
MHGEFPCD_03685	2.25e-45	ywzB	-	-	S	-	-	-	membrane
MHGEFPCD_03686	2.92e-117	ywmA	-	-	-	-	-	-	-
MHGEFPCD_03687	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MHGEFPCD_03688	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHGEFPCD_03689	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHGEFPCD_03690	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHGEFPCD_03691	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHGEFPCD_03692	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHGEFPCD_03693	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHGEFPCD_03694	1.05e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MHGEFPCD_03695	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MHGEFPCD_03696	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHGEFPCD_03697	8.08e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHGEFPCD_03698	3.68e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MHGEFPCD_03699	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MHGEFPCD_03700	1.2e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHGEFPCD_03701	1.36e-118	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHGEFPCD_03702	1.46e-241	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHGEFPCD_03703	4.23e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MHGEFPCD_03704	2.99e-149	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MHGEFPCD_03705	2.08e-79	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MHGEFPCD_03707	1.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHGEFPCD_03708	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHGEFPCD_03709	6.14e-87	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGEFPCD_03710	2.45e-122	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MHGEFPCD_03711	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MHGEFPCD_03712	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MHGEFPCD_03713	4.08e-134	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MHGEFPCD_03714	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MHGEFPCD_03715	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHGEFPCD_03716	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MHGEFPCD_03717	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHGEFPCD_03718	6.37e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHGEFPCD_03719	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MHGEFPCD_03720	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MHGEFPCD_03721	3.31e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MHGEFPCD_03722	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHGEFPCD_03723	2.79e-74	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHGEFPCD_03724	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MHGEFPCD_03725	2.34e-283	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHGEFPCD_03726	8.09e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MHGEFPCD_03727	1.13e-58	ywjC	-	-	-	-	-	-	-
MHGEFPCD_03728	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MHGEFPCD_03729	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHGEFPCD_03730	1.18e-133	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHGEFPCD_03731	8.39e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MHGEFPCD_03732	5.17e-123	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MHGEFPCD_03733	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MHGEFPCD_03734	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHGEFPCD_03735	2.39e-108	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MHGEFPCD_03736	1.24e-177	ywiC	-	-	S	-	-	-	YwiC-like protein
MHGEFPCD_03737	1.33e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MHGEFPCD_03738	4.27e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MHGEFPCD_03739	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MHGEFPCD_03740	1.95e-56	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_03741	5.77e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHGEFPCD_03743	7.54e-40	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
MHGEFPCD_03744	2.41e-45	-	-	-	-	-	-	-	-
MHGEFPCD_03745	1.18e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MHGEFPCD_03747	5.95e-101	-	-	-	CP	-	-	-	Membrane
MHGEFPCD_03750	3.49e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MHGEFPCD_03751	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MHGEFPCD_03752	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHGEFPCD_03753	3.52e-105	-	-	-	-	-	-	-	-
MHGEFPCD_03754	3.32e-124	ywhD	-	-	S	-	-	-	YwhD family
MHGEFPCD_03755	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
MHGEFPCD_03756	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MHGEFPCD_03757	4.16e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03758	2.17e-313	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
MHGEFPCD_03759	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MHGEFPCD_03760	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MHGEFPCD_03761	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MHGEFPCD_03762	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MHGEFPCD_03763	1.8e-66	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
MHGEFPCD_03764	3.1e-119	-	-	-	S	-	-	-	membrane
MHGEFPCD_03765	2.73e-210	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03766	2.96e-215	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MHGEFPCD_03769	3.87e-237	-	-	-	-	-	-	-	-
MHGEFPCD_03771	5.91e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHGEFPCD_03772	2.25e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MHGEFPCD_03773	2.8e-212	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MHGEFPCD_03774	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MHGEFPCD_03775	4.87e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MHGEFPCD_03776	4.87e-180	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MHGEFPCD_03777	3.82e-298	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MHGEFPCD_03778	6.69e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MHGEFPCD_03779	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MHGEFPCD_03780	9.39e-180	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHGEFPCD_03781	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MHGEFPCD_03782	1.15e-145	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MHGEFPCD_03783	9.55e-285	ywfA	-	-	EGP	-	-	-	-transporter
MHGEFPCD_03784	8.47e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MHGEFPCD_03785	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHGEFPCD_03786	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MHGEFPCD_03787	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHGEFPCD_03788	6.34e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHGEFPCD_03789	4.11e-203	-	-	-	T	-	-	-	Histidine kinase
MHGEFPCD_03790	1.5e-161	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_03791	1.31e-100	-	-	-	-	-	-	-	-
MHGEFPCD_03792	1.72e-152	-	-	-	S	-	-	-	ABC-2 family transporter protein
MHGEFPCD_03793	2.66e-221	bcrA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03794	1.15e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MHGEFPCD_03795	1.16e-208	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHGEFPCD_03796	4.32e-232	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHGEFPCD_03797	3.99e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHGEFPCD_03798	1.45e-235	spsG	-	-	M	-	-	-	Spore Coat
MHGEFPCD_03799	3.95e-171	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MHGEFPCD_03800	1.23e-274	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MHGEFPCD_03801	3.88e-205	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MHGEFPCD_03802	2.41e-280	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MHGEFPCD_03803	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MHGEFPCD_03804	9.06e-184	spsA	-	-	M	-	-	-	Spore Coat
MHGEFPCD_03805	1.85e-85	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHGEFPCD_03806	2.17e-76	ywdK	-	-	S	-	-	-	small membrane protein
MHGEFPCD_03807	2.67e-291	ywdJ	-	-	F	-	-	-	Xanthine uracil
MHGEFPCD_03808	3.37e-59	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MHGEFPCD_03809	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHGEFPCD_03810	4.88e-194	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MHGEFPCD_03812	1.16e-114	ywdD	-	-	-	-	-	-	-
MHGEFPCD_03813	1.6e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MHGEFPCD_03814	6.84e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHGEFPCD_03815	3.52e-26	ywdA	-	-	-	-	-	-	-
MHGEFPCD_03816	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MHGEFPCD_03817	9.04e-317	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_03818	2.23e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MHGEFPCD_03820	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHGEFPCD_03821	8.11e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHGEFPCD_03822	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MHGEFPCD_03823	2.97e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MHGEFPCD_03824	1.43e-101	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MHGEFPCD_03825	1.03e-50	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MHGEFPCD_03826	6.76e-84	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MHGEFPCD_03827	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MHGEFPCD_03828	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHGEFPCD_03829	2.21e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHGEFPCD_03830	6.72e-47	ydaS	-	-	S	-	-	-	membrane
MHGEFPCD_03831	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MHGEFPCD_03832	1.72e-287	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHGEFPCD_03833	2.84e-80	gtcA	-	-	S	-	-	-	GtrA-like protein
MHGEFPCD_03834	3.72e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHGEFPCD_03836	1.02e-165	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MHGEFPCD_03837	1.92e-169	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
MHGEFPCD_03838	5.13e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MHGEFPCD_03839	2.73e-303	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MHGEFPCD_03840	1.37e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHGEFPCD_03841	1.25e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHGEFPCD_03842	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03843	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHGEFPCD_03844	1.86e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MHGEFPCD_03845	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MHGEFPCD_03846	1.98e-181	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MHGEFPCD_03847	5.81e-218	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MHGEFPCD_03848	1.46e-284	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MHGEFPCD_03849	3.56e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MHGEFPCD_03850	6.65e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGEFPCD_03851	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHGEFPCD_03852	5.18e-208	gspA	-	-	M	-	-	-	General stress
MHGEFPCD_03853	3.36e-62	ywaE	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_03854	4.98e-249	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHGEFPCD_03855	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MHGEFPCD_03856	1.25e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MHGEFPCD_03857	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MHGEFPCD_03858	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_03859	2.56e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MHGEFPCD_03860	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHGEFPCD_03861	1.53e-289	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHGEFPCD_03862	5.49e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MHGEFPCD_03863	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHGEFPCD_03864	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_03865	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGEFPCD_03866	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MHGEFPCD_03867	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MHGEFPCD_03868	6.01e-141	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MHGEFPCD_03869	2e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_03870	1.38e-230	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHGEFPCD_03871	7.27e-211	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MHGEFPCD_03872	3.18e-77	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MHGEFPCD_03873	1.09e-291	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHGEFPCD_03874	1.67e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_03875	1.08e-63	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHGEFPCD_03876	2.44e-303	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHGEFPCD_03877	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHGEFPCD_03878	4.93e-211	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MHGEFPCD_03879	1.51e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHGEFPCD_03880	1.07e-266	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MHGEFPCD_03881	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MHGEFPCD_03882	1.31e-244	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MHGEFPCD_03883	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MHGEFPCD_03884	9.85e-198	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHGEFPCD_03885	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MHGEFPCD_03886	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MHGEFPCD_03887	1.36e-242	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MHGEFPCD_03888	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MHGEFPCD_03889	1.93e-288	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MHGEFPCD_03890	8.1e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MHGEFPCD_03891	1.51e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHGEFPCD_03892	3.33e-211	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MHGEFPCD_03893	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHGEFPCD_03894	2.68e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MHGEFPCD_03895	9.29e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MHGEFPCD_03896	1.91e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MHGEFPCD_03899	6.11e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MHGEFPCD_03900	6.59e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MHGEFPCD_03901	9.82e-202	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MHGEFPCD_03902	6.69e-267	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHGEFPCD_03903	1.86e-126	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MHGEFPCD_03904	1.32e-59	yxiS	-	-	-	-	-	-	-
MHGEFPCD_03905	2.46e-149	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
MHGEFPCD_03907	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MHGEFPCD_03908	3.17e-281	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MHGEFPCD_03909	7.8e-183	bglS	-	-	M	-	-	-	licheninase activity
MHGEFPCD_03910	1.03e-187	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MHGEFPCD_03911	1.74e-280	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MHGEFPCD_03912	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MHGEFPCD_03914	5.34e-24	-	-	-	-	-	-	-	-
MHGEFPCD_03917	4.21e-91	yxiG	-	-	-	-	-	-	-
MHGEFPCD_03918	1.3e-81	yxxG	-	-	-	-	-	-	-
MHGEFPCD_03920	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MHGEFPCD_03921	3.83e-257	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MHGEFPCD_03922	7.23e-209	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MHGEFPCD_03923	6.99e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MHGEFPCD_03924	0.0	-	-	-	L	-	-	-	HKD family nuclease
MHGEFPCD_03925	2.39e-85	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHGEFPCD_03926	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MHGEFPCD_03927	2.45e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MHGEFPCD_03928	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MHGEFPCD_03929	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MHGEFPCD_03930	3.7e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MHGEFPCD_03931	4.12e-226	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MHGEFPCD_03932	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHGEFPCD_03933	1.1e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MHGEFPCD_03934	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHGEFPCD_03935	8.25e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHGEFPCD_03936	4.77e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHGEFPCD_03937	5.46e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MHGEFPCD_03940	3.51e-36	yxeE	-	-	-	-	-	-	-
MHGEFPCD_03941	5.09e-35	yxeD	-	-	-	-	-	-	-
MHGEFPCD_03942	2.8e-46	-	-	-	-	-	-	-	-
MHGEFPCD_03943	7.14e-229	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MHGEFPCD_03944	4.9e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MHGEFPCD_03945	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHGEFPCD_03946	3.28e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHGEFPCD_03947	2.77e-224	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_03948	7.7e-158	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_03949	2.83e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MHGEFPCD_03950	1.25e-202	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MHGEFPCD_03951	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MHGEFPCD_03952	6.3e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHGEFPCD_03953	2.59e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MHGEFPCD_03954	1.09e-221	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHGEFPCD_03955	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHGEFPCD_03956	2.4e-232	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHGEFPCD_03957	2.43e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHGEFPCD_03958	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHGEFPCD_03959	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MHGEFPCD_03960	4.11e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MHGEFPCD_03961	1.1e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHGEFPCD_03962	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MHGEFPCD_03964	1.24e-194	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MHGEFPCD_03965	6.16e-131	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHGEFPCD_03966	4.6e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_03967	3.53e-255	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MHGEFPCD_03968	6.59e-276	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHGEFPCD_03969	0.0	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHGEFPCD_03970	5.86e-190	yxaL	-	-	S	-	-	-	PQQ-like domain
MHGEFPCD_03971	3.4e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MHGEFPCD_03972	3.47e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MHGEFPCD_03973	5.4e-256	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHGEFPCD_03974	7.8e-97	yxaI	-	-	S	-	-	-	membrane protein domain
MHGEFPCD_03975	1.5e-159	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
MHGEFPCD_03976	1.93e-05	htpX3	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	COG0501 Zn-dependent protease with chaperone function
MHGEFPCD_03977	5.92e-116	mrr2	-	-	V	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
MHGEFPCD_03978	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MHGEFPCD_03979	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MHGEFPCD_03980	5.38e-290	-	-	-	S	-	-	-	Fic/DOC family
MHGEFPCD_03981	3.04e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MHGEFPCD_03982	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MHGEFPCD_03983	8.17e-109	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MHGEFPCD_03984	8.1e-199	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MHGEFPCD_03985	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MHGEFPCD_03986	4e-114	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MHGEFPCD_03987	3.43e-236	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MHGEFPCD_03988	4.48e-234	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MHGEFPCD_03989	2.34e-27	-	-	-	-	-	-	-	-
MHGEFPCD_03990	1.77e-96	-	-	-	K	-	-	-	SIR2-like domain
MHGEFPCD_03991	1.99e-119	-	-	-	D	-	-	-	AAA domain
MHGEFPCD_03992	2.74e-98	-	-	-	-	-	-	-	-
MHGEFPCD_03993	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHGEFPCD_03996	5.91e-280	yycP	-	-	-	-	-	-	-
MHGEFPCD_03997	1.49e-172	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHGEFPCD_03998	2.14e-233	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MHGEFPCD_03999	2.05e-113	yycN	-	-	K	-	-	-	Acetyltransferase
MHGEFPCD_04001	1.29e-259	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MHGEFPCD_04002	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MHGEFPCD_04003	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHGEFPCD_04004	6.81e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHGEFPCD_04005	3.64e-92	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MHGEFPCD_04006	2.69e-57	sdpR	-	-	K	-	-	-	transcriptional
MHGEFPCD_04007	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHGEFPCD_04008	2.62e-188	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
MHGEFPCD_04009	0.0	-	-	-	S	-	-	-	ABC transporter
MHGEFPCD_04010	2.88e-255	-	-	-	S	-	-	-	Major Facilitator Superfamily
MHGEFPCD_04011	0.0	-	-	-	-	-	-	-	-
MHGEFPCD_04012	1.63e-243	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MHGEFPCD_04013	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MHGEFPCD_04014	1.17e-119	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
MHGEFPCD_04015	5.3e-83	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MHGEFPCD_04016	1.9e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHGEFPCD_04017	1.98e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHGEFPCD_04018	1.14e-193	yycI	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_04019	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_04020	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHGEFPCD_04021	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHGEFPCD_04026	7.42e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHGEFPCD_04027	1.02e-90	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGEFPCD_04028	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MHGEFPCD_04029	7.68e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MHGEFPCD_04031	5.12e-25	yycC	-	-	K	-	-	-	YycC-like protein
MHGEFPCD_04032	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHGEFPCD_04033	1.47e-304	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MHGEFPCD_04034	9.45e-261	-	-	-	S	-	-	-	Ecdysteroid kinase
MHGEFPCD_04035	1.61e-297	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
MHGEFPCD_04036	9.47e-299	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MHGEFPCD_04037	1.46e-155	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MHGEFPCD_04038	1.18e-114	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
MHGEFPCD_04039	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MHGEFPCD_04040	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MHGEFPCD_04041	1.44e-203	yybS	-	-	S	-	-	-	membrane
MHGEFPCD_04043	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MHGEFPCD_04044	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_04045	2.42e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MHGEFPCD_04046	1.69e-211	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHGEFPCD_04047	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MHGEFPCD_04048	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MHGEFPCD_04049	8.03e-151	-	-	-	K	-	-	-	FCD domain
MHGEFPCD_04050	5.53e-117	-	-	-	S	-	-	-	PFAM DinB family protein
MHGEFPCD_04051	2.34e-204	-	-	-	G	-	-	-	Major Facilitator Superfamily
MHGEFPCD_04053	1.31e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MHGEFPCD_04054	4.87e-148	ydgI	-	-	C	-	-	-	nitroreductase
MHGEFPCD_04055	6.79e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MHGEFPCD_04056	1.38e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHGEFPCD_04057	1.3e-99	yybA	-	-	K	-	-	-	transcriptional
MHGEFPCD_04058	4.45e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MHGEFPCD_04059	2.75e-210	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
MHGEFPCD_04060	1.44e-27	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHGEFPCD_04061	9.05e-61	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
MHGEFPCD_04062	7.14e-14	-	-	-	S	ko:K07137	-	ko00000	Pyridine nucleotide-disulphide oxidoreductase
MHGEFPCD_04063	3.4e-126	-	-	-	-	-	-	-	-
MHGEFPCD_04064	1.33e-86	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
MHGEFPCD_04066	1.01e-82	-	-	-	O	-	-	-	Subtilase family
MHGEFPCD_04067	3.88e-315	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHGEFPCD_04068	1.83e-164	-	-	-	EG	-	-	-	EamA-like transporter family
MHGEFPCD_04069	6.84e-156	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MHGEFPCD_04071	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MHGEFPCD_04072	2.96e-210	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHGEFPCD_04073	3e-315	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MHGEFPCD_04074	1.11e-84	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHGEFPCD_04075	6.62e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
MHGEFPCD_04076	1.45e-50	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MHGEFPCD_04077	9.69e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHGEFPCD_04078	1.54e-137	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MHGEFPCD_04079	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHGEFPCD_04080	4.77e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHGEFPCD_04081	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MHGEFPCD_04082	7.69e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHGEFPCD_04083	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHGEFPCD_04084	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MHGEFPCD_04085	1.94e-224	yyaD	-	-	S	-	-	-	Membrane
MHGEFPCD_04086	4.91e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MHGEFPCD_04087	8.27e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MHGEFPCD_04088	1.18e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MHGEFPCD_04089	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHGEFPCD_04090	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHGEFPCD_04091	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHGEFPCD_04092	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHGEFPCD_04093	7.7e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MHGEFPCD_04094	1.74e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHGEFPCD_04095	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme