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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IOPMGPNG_00001	5.55e-301	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOPMGPNG_00002	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOPMGPNG_00003	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IOPMGPNG_00004	1.25e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOPMGPNG_00005	7.23e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
IOPMGPNG_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOPMGPNG_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOPMGPNG_00008	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00011	7.47e-233	yaaC	-	-	S	-	-	-	YaaC-like Protein
IOPMGPNG_00012	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOPMGPNG_00013	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOPMGPNG_00014	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOPMGPNG_00015	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOPMGPNG_00016	1.14e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOPMGPNG_00018	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
IOPMGPNG_00019	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
IOPMGPNG_00020	2.11e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
IOPMGPNG_00021	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
IOPMGPNG_00022	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOPMGPNG_00023	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOPMGPNG_00024	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOPMGPNG_00025	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOPMGPNG_00026	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IOPMGPNG_00027	6.2e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
IOPMGPNG_00028	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00031	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
IOPMGPNG_00032	2.58e-130	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IOPMGPNG_00033	1.39e-257	yaaN	-	-	P	-	-	-	Belongs to the TelA family
IOPMGPNG_00034	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
IOPMGPNG_00035	4.67e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOPMGPNG_00036	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00037	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
IOPMGPNG_00038	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IOPMGPNG_00039	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IOPMGPNG_00040	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IOPMGPNG_00041	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
IOPMGPNG_00042	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IOPMGPNG_00043	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOPMGPNG_00044	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
IOPMGPNG_00045	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOPMGPNG_00046	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
IOPMGPNG_00047	1.67e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
IOPMGPNG_00048	1.43e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOPMGPNG_00049	5.04e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOPMGPNG_00050	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
IOPMGPNG_00051	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00052	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOPMGPNG_00053	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IOPMGPNG_00054	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
IOPMGPNG_00055	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IOPMGPNG_00056	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOPMGPNG_00057	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOPMGPNG_00058	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOPMGPNG_00059	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOPMGPNG_00060	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
IOPMGPNG_00061	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOPMGPNG_00062	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
IOPMGPNG_00063	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOPMGPNG_00064	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IOPMGPNG_00065	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IOPMGPNG_00066	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
IOPMGPNG_00067	5.21e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
IOPMGPNG_00068	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IOPMGPNG_00069	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IOPMGPNG_00072	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
IOPMGPNG_00073	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IOPMGPNG_00074	2.82e-235	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IOPMGPNG_00075	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOPMGPNG_00076	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IOPMGPNG_00077	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOPMGPNG_00078	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOPMGPNG_00079	1.3e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOPMGPNG_00080	8.93e-172	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
IOPMGPNG_00081	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IOPMGPNG_00082	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOPMGPNG_00083	5.98e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
IOPMGPNG_00084	1.54e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
IOPMGPNG_00085	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOPMGPNG_00086	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOPMGPNG_00087	2.64e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IOPMGPNG_00088	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
IOPMGPNG_00089	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOPMGPNG_00090	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IOPMGPNG_00091	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00101	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00102	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IOPMGPNG_00103	6.76e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
IOPMGPNG_00104	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IOPMGPNG_00105	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IOPMGPNG_00106	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOPMGPNG_00107	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IOPMGPNG_00108	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
IOPMGPNG_00109	8.66e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOPMGPNG_00110	2.59e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOPMGPNG_00111	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOPMGPNG_00112	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
IOPMGPNG_00113	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IOPMGPNG_00114	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOPMGPNG_00115	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOPMGPNG_00116	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IOPMGPNG_00117	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IOPMGPNG_00118	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOPMGPNG_00119	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IOPMGPNG_00120	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOPMGPNG_00121	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOPMGPNG_00122	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOPMGPNG_00123	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOPMGPNG_00124	9.89e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IOPMGPNG_00125	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOPMGPNG_00126	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOPMGPNG_00127	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
IOPMGPNG_00128	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOPMGPNG_00129	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOPMGPNG_00130	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOPMGPNG_00131	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOPMGPNG_00132	4.3e-229	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
IOPMGPNG_00133	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IOPMGPNG_00134	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOPMGPNG_00135	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IOPMGPNG_00136	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOPMGPNG_00137	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOPMGPNG_00138	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOPMGPNG_00139	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOPMGPNG_00140	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOPMGPNG_00141	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOPMGPNG_00142	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IOPMGPNG_00143	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOPMGPNG_00144	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOPMGPNG_00145	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOPMGPNG_00146	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOPMGPNG_00147	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOPMGPNG_00148	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOPMGPNG_00149	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOPMGPNG_00150	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOPMGPNG_00151	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOPMGPNG_00152	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IOPMGPNG_00153	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOPMGPNG_00154	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOPMGPNG_00155	6.17e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOPMGPNG_00156	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOPMGPNG_00157	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOPMGPNG_00158	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IOPMGPNG_00159	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOPMGPNG_00160	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOPMGPNG_00161	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOPMGPNG_00162	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IOPMGPNG_00163	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOPMGPNG_00164	3.67e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOPMGPNG_00165	3.23e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOPMGPNG_00166	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOPMGPNG_00167	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOPMGPNG_00168	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IOPMGPNG_00169	6.15e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
IOPMGPNG_00170	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
IOPMGPNG_00171	5.24e-169	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IOPMGPNG_00172	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOPMGPNG_00173	4.25e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
IOPMGPNG_00174	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
IOPMGPNG_00175	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
IOPMGPNG_00176	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00183	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00184	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00186	2.61e-316	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IOPMGPNG_00188	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
IOPMGPNG_00189	5.87e-177	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
IOPMGPNG_00190	2.37e-226	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00191	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00192	1.26e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
IOPMGPNG_00193	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
IOPMGPNG_00194	8.14e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00195	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
IOPMGPNG_00196	1.27e-285	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
IOPMGPNG_00197	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_00198	9e-193	ybbH	-	-	K	-	-	-	transcriptional
IOPMGPNG_00199	1.35e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOPMGPNG_00200	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
IOPMGPNG_00201	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
IOPMGPNG_00207	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_00208	1.85e-150	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IOPMGPNG_00209	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOPMGPNG_00210	3.41e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00211	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOPMGPNG_00212	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOPMGPNG_00213	8.65e-226	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOPMGPNG_00214	3.31e-150	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
IOPMGPNG_00215	4.31e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOPMGPNG_00216	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOPMGPNG_00217	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
IOPMGPNG_00218	1.99e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
IOPMGPNG_00219	3.12e-61	-	-	-	-	-	-	-	-
IOPMGPNG_00220	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IOPMGPNG_00221	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
IOPMGPNG_00222	3.13e-256	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IOPMGPNG_00223	6e-76	-	-	-	-	-	-	-	-
IOPMGPNG_00224	3.83e-59	-	-	-	V	-	-	-	Beta-lactamase
IOPMGPNG_00226	4.05e-101	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOPMGPNG_00227	6.22e-277	-	-	-	S	-	-	-	Protein of unknown function (DUF1430)
IOPMGPNG_00229	3.67e-193	ybdN	-	-	-	-	-	-	-
IOPMGPNG_00230	4.65e-276	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
IOPMGPNG_00231	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_00232	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
IOPMGPNG_00233	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
IOPMGPNG_00234	1.51e-192	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
IOPMGPNG_00235	2.67e-314	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
IOPMGPNG_00236	1.11e-54	ybyB	-	-	-	-	-	-	-
IOPMGPNG_00237	0.0	ybeC	-	-	E	-	-	-	amino acid
IOPMGPNG_00238	9.95e-211	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
IOPMGPNG_00239	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
IOPMGPNG_00240	3.44e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IOPMGPNG_00241	3.34e-215	ybfA	-	-	K	-	-	-	FR47-like protein
IOPMGPNG_00242	3.07e-283	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_00244	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IOPMGPNG_00245	7.49e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_00246	2.12e-187	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
IOPMGPNG_00247	5.85e-274	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOPMGPNG_00248	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
IOPMGPNG_00250	4.39e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IOPMGPNG_00251	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOPMGPNG_00252	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
IOPMGPNG_00253	1.76e-189	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IOPMGPNG_00254	1.85e-58	ybfN	-	-	-	-	-	-	-
IOPMGPNG_00255	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
IOPMGPNG_00256	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_00257	4.74e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IOPMGPNG_00258	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOPMGPNG_00259	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_00260	4.29e-174	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOPMGPNG_00261	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IOPMGPNG_00263	3.08e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IOPMGPNG_00264	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOPMGPNG_00265	9.76e-229	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
IOPMGPNG_00266	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IOPMGPNG_00267	3.06e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IOPMGPNG_00268	2.05e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_00269	5.76e-216	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
IOPMGPNG_00270	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
IOPMGPNG_00271	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOPMGPNG_00272	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_00273	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOPMGPNG_00274	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
IOPMGPNG_00275	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IOPMGPNG_00276	6.07e-223	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
IOPMGPNG_00277	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
IOPMGPNG_00278	3.2e-216	eamA1	-	-	EG	-	-	-	spore germination
IOPMGPNG_00279	1.7e-158	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_00280	3.75e-215	ycbM	-	-	T	-	-	-	Histidine kinase
IOPMGPNG_00281	2.36e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_00282	2.46e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
IOPMGPNG_00283	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IOPMGPNG_00284	5.22e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IOPMGPNG_00285	7.74e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
IOPMGPNG_00286	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
IOPMGPNG_00287	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOPMGPNG_00288	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOPMGPNG_00289	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOPMGPNG_00290	4.17e-260	ycbU	-	-	E	-	-	-	Selenocysteine lyase
IOPMGPNG_00291	2.51e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IOPMGPNG_00292	1.88e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IOPMGPNG_00293	2.4e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IOPMGPNG_00294	6.64e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOPMGPNG_00295	1.14e-73	-	-	-	S	-	-	-	RDD family
IOPMGPNG_00296	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
IOPMGPNG_00297	1.3e-214	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IOPMGPNG_00298	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IOPMGPNG_00299	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOPMGPNG_00300	7.66e-255	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOPMGPNG_00301	3.37e-222	yccK	-	-	C	-	-	-	Aldo keto reductase
IOPMGPNG_00302	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
IOPMGPNG_00303	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_00304	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_00305	2.65e-123	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IOPMGPNG_00306	2.86e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
IOPMGPNG_00307	1.96e-179	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_00308	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOPMGPNG_00309	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOPMGPNG_00310	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOPMGPNG_00311	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOPMGPNG_00312	2.23e-233	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOPMGPNG_00313	3.08e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
IOPMGPNG_00314	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IOPMGPNG_00315	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IOPMGPNG_00316	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
IOPMGPNG_00317	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
IOPMGPNG_00318	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
IOPMGPNG_00319	1.9e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
IOPMGPNG_00320	3.34e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IOPMGPNG_00321	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOPMGPNG_00322	3.66e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IOPMGPNG_00323	1.21e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOPMGPNG_00324	1.16e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IOPMGPNG_00325	5.41e-274	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
IOPMGPNG_00326	0.0	ycgA	-	-	S	-	-	-	Membrane
IOPMGPNG_00327	2.72e-105	ycgB	-	-	-	-	-	-	-
IOPMGPNG_00328	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IOPMGPNG_00329	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IOPMGPNG_00330	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IOPMGPNG_00331	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
IOPMGPNG_00332	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_00333	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
IOPMGPNG_00334	2.07e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IOPMGPNG_00335	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_00336	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
IOPMGPNG_00337	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOPMGPNG_00338	2.54e-138	tmrB	-	-	S	-	-	-	AAA domain
IOPMGPNG_00339	1.74e-135	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IOPMGPNG_00340	3.56e-184	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
IOPMGPNG_00341	2.99e-223	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
IOPMGPNG_00342	7.44e-230	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
IOPMGPNG_00343	2.6e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
IOPMGPNG_00344	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IOPMGPNG_00345	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOPMGPNG_00346	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOPMGPNG_00347	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
IOPMGPNG_00348	5.6e-192	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
IOPMGPNG_00349	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
IOPMGPNG_00350	1.52e-205	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
IOPMGPNG_00351	1.48e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IOPMGPNG_00352	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IOPMGPNG_00353	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
IOPMGPNG_00354	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IOPMGPNG_00355	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOPMGPNG_00356	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
IOPMGPNG_00357	3.18e-282	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IOPMGPNG_00358	2.27e-217	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
IOPMGPNG_00359	1.04e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IOPMGPNG_00360	3.22e-289	yciC	-	-	S	-	-	-	GTPases (G3E family)
IOPMGPNG_00361	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOPMGPNG_00362	6.23e-186	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IOPMGPNG_00364	4.48e-91	yckC	-	-	S	-	-	-	membrane
IOPMGPNG_00365	3.53e-69	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
IOPMGPNG_00366	1.05e-50	-	-	-	K	-	-	-	MarR family
IOPMGPNG_00367	3.65e-31	-	-	-	-	-	-	-	-
IOPMGPNG_00368	1.64e-154	-	-	-	S	-	-	-	AAA domain
IOPMGPNG_00369	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOPMGPNG_00370	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
IOPMGPNG_00371	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IOPMGPNG_00372	1.52e-267	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_00373	1.13e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
IOPMGPNG_00374	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
IOPMGPNG_00375	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
IOPMGPNG_00376	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_00377	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_00378	8.39e-116	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IOPMGPNG_00379	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IOPMGPNG_00380	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
IOPMGPNG_00381	6.53e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOPMGPNG_00382	3.79e-125	-	-	-	S	-	-	-	YcxB-like protein
IOPMGPNG_00383	3.27e-205	ycxC	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_00384	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
IOPMGPNG_00385	4.76e-145	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
IOPMGPNG_00386	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
IOPMGPNG_00387	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOPMGPNG_00388	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOPMGPNG_00389	1.23e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IOPMGPNG_00390	8.83e-208	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
IOPMGPNG_00391	1.35e-141	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IOPMGPNG_00392	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IOPMGPNG_00393	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
IOPMGPNG_00394	5.92e-107	yclD	-	-	-	-	-	-	-
IOPMGPNG_00395	3.87e-202	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
IOPMGPNG_00396	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
IOPMGPNG_00397	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
IOPMGPNG_00399	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IOPMGPNG_00400	5.79e-288	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
IOPMGPNG_00401	3.33e-247	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
IOPMGPNG_00402	5.63e-154	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IOPMGPNG_00403	4.04e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
IOPMGPNG_00404	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_00405	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOPMGPNG_00406	7.15e-104	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IOPMGPNG_00408	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IOPMGPNG_00409	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IOPMGPNG_00410	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOPMGPNG_00411	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00412	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00413	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_00414	7.91e-220	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IOPMGPNG_00415	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
IOPMGPNG_00416	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_00417	2.48e-173	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IOPMGPNG_00418	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
IOPMGPNG_00419	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOPMGPNG_00420	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOPMGPNG_00421	1.89e-310	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOPMGPNG_00422	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOPMGPNG_00423	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IOPMGPNG_00424	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_00425	3.83e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00426	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
IOPMGPNG_00427	2.88e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOPMGPNG_00428	9.44e-75	-	-	-	-	-	-	-	-
IOPMGPNG_00429	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
IOPMGPNG_00430	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IOPMGPNG_00431	5.13e-267	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
IOPMGPNG_00432	8.33e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
IOPMGPNG_00433	3.78e-126	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOPMGPNG_00434	1.71e-143	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
IOPMGPNG_00435	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IOPMGPNG_00437	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IOPMGPNG_00438	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
IOPMGPNG_00439	1.32e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
IOPMGPNG_00440	2.01e-189	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
IOPMGPNG_00441	5.04e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IOPMGPNG_00442	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IOPMGPNG_00443	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_00444	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
IOPMGPNG_00446	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
IOPMGPNG_00447	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
IOPMGPNG_00448	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
IOPMGPNG_00449	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
IOPMGPNG_00450	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
IOPMGPNG_00451	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
IOPMGPNG_00452	1.07e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_00453	2.75e-125	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IOPMGPNG_00454	2.69e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOPMGPNG_00455	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
IOPMGPNG_00456	3.61e-176	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IOPMGPNG_00457	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
IOPMGPNG_00458	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IOPMGPNG_00459	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOPMGPNG_00460	1.78e-266	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IOPMGPNG_00461	5.21e-192	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IOPMGPNG_00462	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
IOPMGPNG_00463	3.89e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
IOPMGPNG_00464	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
IOPMGPNG_00465	0.0	ydaO	-	-	E	-	-	-	amino acid
IOPMGPNG_00466	1.47e-100	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IOPMGPNG_00467	1.53e-211	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOPMGPNG_00468	1.52e-161	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IOPMGPNG_00469	2.14e-53	-	-	-	-	-	-	-	-
IOPMGPNG_00470	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IOPMGPNG_00471	1.67e-42	ydaS	-	-	S	-	-	-	membrane
IOPMGPNG_00472	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IOPMGPNG_00473	2.91e-188	ydbA	-	-	P	-	-	-	EcsC protein family
IOPMGPNG_00474	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
IOPMGPNG_00475	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
IOPMGPNG_00476	2.2e-83	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
IOPMGPNG_00477	1.29e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
IOPMGPNG_00478	1.23e-251	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IOPMGPNG_00479	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IOPMGPNG_00480	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IOPMGPNG_00481	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOPMGPNG_00482	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
IOPMGPNG_00484	2.18e-217	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_00485	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOPMGPNG_00486	1.32e-69	ydbL	-	-	-	-	-	-	-
IOPMGPNG_00487	5.87e-277	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
IOPMGPNG_00488	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
IOPMGPNG_00490	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOPMGPNG_00491	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
IOPMGPNG_00492	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IOPMGPNG_00493	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOPMGPNG_00494	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOPMGPNG_00495	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IOPMGPNG_00496	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
IOPMGPNG_00497	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
IOPMGPNG_00498	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOPMGPNG_00499	1.9e-233	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
IOPMGPNG_00500	1.77e-282	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOPMGPNG_00501	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IOPMGPNG_00502	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IOPMGPNG_00503	2.46e-183	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
IOPMGPNG_00504	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
IOPMGPNG_00505	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IOPMGPNG_00506	1.86e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
IOPMGPNG_00507	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
IOPMGPNG_00508	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IOPMGPNG_00509	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_00510	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
IOPMGPNG_00511	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
IOPMGPNG_00512	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IOPMGPNG_00520	6.29e-93	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_00522	7.81e-57	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOPMGPNG_00524	6.92e-58	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
IOPMGPNG_00525	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
IOPMGPNG_00526	6.17e-101	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IOPMGPNG_00527	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IOPMGPNG_00528	3.47e-52	-	-	-	-	-	-	-	-
IOPMGPNG_00529	3.35e-245	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IOPMGPNG_00530	4.39e-05	-	-	-	S	-	-	-	Nitrate reductase delta subunit
IOPMGPNG_00531	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IOPMGPNG_00532	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
IOPMGPNG_00533	8e-181	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOPMGPNG_00534	2.97e-211	-	-	-	K	-	-	-	AraC-like ligand binding domain
IOPMGPNG_00535	1.37e-221	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOPMGPNG_00536	1.65e-208	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IOPMGPNG_00537	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOPMGPNG_00538	7.66e-277	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
IOPMGPNG_00539	9.2e-70	ydeH	-	-	-	-	-	-	-
IOPMGPNG_00540	6.99e-136	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IOPMGPNG_00541	1.55e-143	-	-	-	-	-	-	-	-
IOPMGPNG_00542	3.24e-99	-	-	-	I	-	-	-	Ribosomal RNA adenine dimethylase
IOPMGPNG_00543	6.75e-147	-	-	-	T	-	-	-	Transcriptional regulator
IOPMGPNG_00544	3.96e-178	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
IOPMGPNG_00545	6.57e-22	-	-	-	S	-	-	-	SNARE associated Golgi protein
IOPMGPNG_00547	4.69e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IOPMGPNG_00548	2.44e-110	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IOPMGPNG_00549	5.21e-194	ydeK	-	-	EG	-	-	-	-transporter
IOPMGPNG_00550	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOPMGPNG_00551	1.06e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
IOPMGPNG_00552	2.88e-136	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IOPMGPNG_00553	9.73e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOPMGPNG_00554	5.03e-91	ydeP	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_00555	6.98e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
IOPMGPNG_00556	1.49e-154	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IOPMGPNG_00557	4.58e-88	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IOPMGPNG_00558	2.16e-135	ydeS	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_00559	1.05e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
IOPMGPNG_00560	5.02e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOPMGPNG_00561	3.28e-190	-	-	-	J	-	-	-	GNAT acetyltransferase
IOPMGPNG_00562	2.5e-206	-	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_00563	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOPMGPNG_00564	1.2e-150	ydfE	-	-	S	-	-	-	Flavin reductase like domain
IOPMGPNG_00565	7.44e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IOPMGPNG_00566	2.18e-101	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOPMGPNG_00568	2.77e-251	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_00569	3.82e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_00570	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
IOPMGPNG_00571	3.8e-223	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IOPMGPNG_00572	2.27e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IOPMGPNG_00573	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IOPMGPNG_00574	5.22e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOPMGPNG_00575	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
IOPMGPNG_00576	4.51e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IOPMGPNG_00577	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
IOPMGPNG_00578	1.08e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
IOPMGPNG_00579	4.84e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IOPMGPNG_00580	5.33e-39	-	-	-	-	-	-	-	-
IOPMGPNG_00582	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOPMGPNG_00583	1.49e-158	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOPMGPNG_00584	1.05e-97	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOPMGPNG_00585	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IOPMGPNG_00586	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IOPMGPNG_00587	1.41e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOPMGPNG_00588	8.18e-70	-	-	-	S	-	-	-	DoxX-like family
IOPMGPNG_00589	4.66e-110	yycN	-	-	K	-	-	-	Acetyltransferase
IOPMGPNG_00590	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
IOPMGPNG_00591	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_00592	7.22e-119	-	-	-	S	-	-	-	DinB family
IOPMGPNG_00593	6.89e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_00594	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
IOPMGPNG_00595	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
IOPMGPNG_00596	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IOPMGPNG_00597	5.97e-267	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IOPMGPNG_00598	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOPMGPNG_00599	5.24e-158	ydhC	-	-	K	-	-	-	FCD
IOPMGPNG_00600	2.1e-308	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
IOPMGPNG_00601	1.31e-287	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOPMGPNG_00602	4.11e-161	-	-	-	-	-	-	-	-
IOPMGPNG_00603	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IOPMGPNG_00604	3.33e-89	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IOPMGPNG_00606	2.02e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_00607	1.98e-233	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IOPMGPNG_00608	8.08e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
IOPMGPNG_00609	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IOPMGPNG_00610	7.97e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_00611	5.01e-69	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_00612	2.65e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOPMGPNG_00613	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOPMGPNG_00614	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IOPMGPNG_00615	2.55e-216	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
IOPMGPNG_00616	2.52e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOPMGPNG_00617	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
IOPMGPNG_00618	4.89e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
IOPMGPNG_00621	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00624	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IOPMGPNG_00625	7.42e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IOPMGPNG_00626	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
IOPMGPNG_00627	2.84e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IOPMGPNG_00628	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOPMGPNG_00629	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IOPMGPNG_00630	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IOPMGPNG_00631	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOPMGPNG_00632	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOPMGPNG_00633	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOPMGPNG_00634	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
IOPMGPNG_00635	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOPMGPNG_00636	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOPMGPNG_00637	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOPMGPNG_00638	1.09e-192	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
IOPMGPNG_00639	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IOPMGPNG_00640	1.02e-256	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IOPMGPNG_00641	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
IOPMGPNG_00642	2.35e-218	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IOPMGPNG_00643	7.61e-148	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
IOPMGPNG_00644	4.25e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOPMGPNG_00645	3.5e-171	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
IOPMGPNG_00646	1.47e-202	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
IOPMGPNG_00647	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
IOPMGPNG_00648	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOPMGPNG_00649	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IOPMGPNG_00650	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
IOPMGPNG_00651	1.39e-208	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IOPMGPNG_00653	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
IOPMGPNG_00654	1.25e-202	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IOPMGPNG_00655	1.38e-226	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
IOPMGPNG_00656	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
IOPMGPNG_00657	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_00658	6.13e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOPMGPNG_00660	4.62e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
IOPMGPNG_00661	9.57e-287	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IOPMGPNG_00662	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
IOPMGPNG_00663	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IOPMGPNG_00664	1.44e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_00665	4.27e-310	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
IOPMGPNG_00666	3.27e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IOPMGPNG_00667	1.95e-163	yebC	-	-	M	-	-	-	Membrane
IOPMGPNG_00669	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
IOPMGPNG_00670	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
IOPMGPNG_00671	9.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOPMGPNG_00672	4.46e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOPMGPNG_00673	9.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOPMGPNG_00674	1.18e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IOPMGPNG_00675	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOPMGPNG_00676	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOPMGPNG_00677	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOPMGPNG_00678	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOPMGPNG_00679	1.71e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IOPMGPNG_00680	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOPMGPNG_00681	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IOPMGPNG_00682	3.29e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IOPMGPNG_00683	2.51e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
IOPMGPNG_00684	1.75e-293	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
IOPMGPNG_00685	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
IOPMGPNG_00686	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
IOPMGPNG_00687	7.87e-243	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
IOPMGPNG_00688	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00689	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
IOPMGPNG_00690	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IOPMGPNG_00691	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IOPMGPNG_00692	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOPMGPNG_00693	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
IOPMGPNG_00694	3.34e-248	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
IOPMGPNG_00695	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IOPMGPNG_00696	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOPMGPNG_00697	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOPMGPNG_00698	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOPMGPNG_00699	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOPMGPNG_00700	1.47e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_00701	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IOPMGPNG_00702	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOPMGPNG_00703	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOPMGPNG_00704	4.4e-101	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
IOPMGPNG_00705	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
IOPMGPNG_00706	7.2e-117	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IOPMGPNG_00707	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IOPMGPNG_00708	1.12e-138	-	-	-	S	ko:K07043	-	ko00000	WLM domain
IOPMGPNG_00710	1.83e-65	-	-	-	-	-	-	-	-
IOPMGPNG_00711	9.01e-16	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IOPMGPNG_00712	5.51e-72	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IOPMGPNG_00713	3.16e-69	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IOPMGPNG_00714	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
IOPMGPNG_00716	3.26e-125	-	-	-	L	-	-	-	endonuclease activity
IOPMGPNG_00717	1.86e-15	-	-	-	S	-	-	-	Lysozyme inhibitor LprI
IOPMGPNG_00718	4.97e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IOPMGPNG_00720	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IOPMGPNG_00722	9.93e-130	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_00723	2.02e-106	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
IOPMGPNG_00724	1.01e-194	yesF	-	-	GM	-	-	-	NAD(P)H-binding
IOPMGPNG_00725	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
IOPMGPNG_00726	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
IOPMGPNG_00727	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
IOPMGPNG_00728	1.39e-129	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IOPMGPNG_00730	1.48e-131	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
IOPMGPNG_00731	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_00732	1.62e-256	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IOPMGPNG_00733	4.82e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOPMGPNG_00734	1.83e-212	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOPMGPNG_00735	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOPMGPNG_00736	8e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IOPMGPNG_00737	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_00738	6.35e-165	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOPMGPNG_00739	3.06e-164	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
IOPMGPNG_00740	6.66e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IOPMGPNG_00741	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IOPMGPNG_00742	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IOPMGPNG_00743	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOPMGPNG_00744	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IOPMGPNG_00745	0.0	yetA	-	-	-	-	-	-	-
IOPMGPNG_00746	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOPMGPNG_00747	2.39e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IOPMGPNG_00748	1.3e-207	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOPMGPNG_00749	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IOPMGPNG_00750	1.49e-156	yetF	-	-	S	-	-	-	membrane
IOPMGPNG_00751	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
IOPMGPNG_00752	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOPMGPNG_00753	1.16e-181	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOPMGPNG_00754	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
IOPMGPNG_00755	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IOPMGPNG_00756	2.1e-202	-	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_00757	1.12e-115	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_00758	2.43e-263	yetM	-	-	CH	-	-	-	FAD binding domain
IOPMGPNG_00759	6.1e-255	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
IOPMGPNG_00760	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IOPMGPNG_00761	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IOPMGPNG_00762	2.41e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
IOPMGPNG_00763	9.86e-237	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
IOPMGPNG_00764	3.99e-231	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IOPMGPNG_00765	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
IOPMGPNG_00766	2.84e-244	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IOPMGPNG_00767	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_00768	9.43e-171	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOPMGPNG_00769	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IOPMGPNG_00770	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOPMGPNG_00771	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
IOPMGPNG_00772	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOPMGPNG_00773	6.48e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
IOPMGPNG_00774	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
IOPMGPNG_00775	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
IOPMGPNG_00776	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOPMGPNG_00777	4.19e-263	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
IOPMGPNG_00778	3.75e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
IOPMGPNG_00779	1.71e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
IOPMGPNG_00780	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IOPMGPNG_00781	4.94e-222	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00782	7.82e-219	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00783	6.38e-209	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IOPMGPNG_00784	3.01e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
IOPMGPNG_00785	3.45e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
IOPMGPNG_00786	1.42e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IOPMGPNG_00787	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IOPMGPNG_00788	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IOPMGPNG_00789	1.88e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IOPMGPNG_00790	1.14e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
IOPMGPNG_00791	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IOPMGPNG_00792	9.84e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOPMGPNG_00793	7.95e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IOPMGPNG_00794	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IOPMGPNG_00795	1.7e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_00796	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
IOPMGPNG_00797	2.82e-26	yflI	-	-	-	-	-	-	-
IOPMGPNG_00798	2.1e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IOPMGPNG_00799	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IOPMGPNG_00800	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IOPMGPNG_00801	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IOPMGPNG_00802	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
IOPMGPNG_00803	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IOPMGPNG_00804	1.04e-247	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
IOPMGPNG_00806	1.08e-269	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
IOPMGPNG_00807	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IOPMGPNG_00808	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_00809	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOPMGPNG_00810	7.17e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
IOPMGPNG_00811	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
IOPMGPNG_00812	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOPMGPNG_00813	5.48e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IOPMGPNG_00814	3.59e-265	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_00815	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
IOPMGPNG_00816	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOPMGPNG_00817	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
IOPMGPNG_00818	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IOPMGPNG_00819	2.74e-11	-	-	-	-	-	-	-	-
IOPMGPNG_00820	4.48e-277	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_00821	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
IOPMGPNG_00822	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
IOPMGPNG_00823	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
IOPMGPNG_00824	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
IOPMGPNG_00825	3.26e-36	yfjT	-	-	-	-	-	-	-
IOPMGPNG_00826	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
IOPMGPNG_00827	4.43e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IOPMGPNG_00828	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
IOPMGPNG_00829	7.91e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOPMGPNG_00830	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOPMGPNG_00831	5.9e-57	-	-	-	S	-	-	-	YfzA-like protein
IOPMGPNG_00832	4.35e-237	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOPMGPNG_00833	1.53e-107	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IOPMGPNG_00835	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOPMGPNG_00836	8.81e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOPMGPNG_00837	2.7e-261	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOPMGPNG_00838	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOPMGPNG_00839	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
IOPMGPNG_00840	2.75e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
IOPMGPNG_00841	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
IOPMGPNG_00842	1.9e-109	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
IOPMGPNG_00843	3.83e-161	yfjC	-	-	-	-	-	-	-
IOPMGPNG_00844	6.91e-241	yfjB	-	-	-	-	-	-	-
IOPMGPNG_00845	1.6e-60	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
IOPMGPNG_00846	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOPMGPNG_00847	8.69e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IOPMGPNG_00848	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_00849	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOPMGPNG_00850	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOPMGPNG_00851	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
IOPMGPNG_00852	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IOPMGPNG_00854	1.98e-271	baeS	-	-	T	-	-	-	Histidine kinase
IOPMGPNG_00855	4.1e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
IOPMGPNG_00856	4.37e-214	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_00857	1.78e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IOPMGPNG_00858	3.67e-257	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IOPMGPNG_00859	1.89e-128	padR	-	-	K	-	-	-	transcriptional
IOPMGPNG_00860	3.2e-127	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOPMGPNG_00861	1.33e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IOPMGPNG_00862	9.43e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
IOPMGPNG_00863	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IOPMGPNG_00864	8.59e-103	yfiV	-	-	K	-	-	-	transcriptional
IOPMGPNG_00865	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOPMGPNG_00866	3.15e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOPMGPNG_00867	6.07e-223	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00868	5.11e-214	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_00869	9.95e-211	yfhB	-	-	S	-	-	-	PhzF family
IOPMGPNG_00870	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
IOPMGPNG_00871	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
IOPMGPNG_00873	4.42e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
IOPMGPNG_00874	5.39e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IOPMGPNG_00875	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
IOPMGPNG_00876	3.47e-268	yfhI	-	-	EGP	-	-	-	-transporter
IOPMGPNG_00877	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
IOPMGPNG_00878	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
IOPMGPNG_00879	2.94e-118	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
IOPMGPNG_00880	1.27e-65	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
IOPMGPNG_00881	3.23e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
IOPMGPNG_00882	8.09e-235	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOPMGPNG_00883	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IOPMGPNG_00884	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
IOPMGPNG_00885	5.31e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
IOPMGPNG_00886	1.73e-48	yfhS	-	-	-	-	-	-	-
IOPMGPNG_00887	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_00888	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
IOPMGPNG_00889	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
IOPMGPNG_00890	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IOPMGPNG_00891	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IOPMGPNG_00892	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
IOPMGPNG_00893	2.68e-311	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IOPMGPNG_00894	1.19e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
IOPMGPNG_00895	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IOPMGPNG_00896	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
IOPMGPNG_00897	1.36e-213	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
IOPMGPNG_00898	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_00915	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
IOPMGPNG_00916	9.17e-36	-	-	-	-	-	-	-	-
IOPMGPNG_00917	2.07e-98	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IOPMGPNG_00918	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOPMGPNG_00919	1.16e-213	ygaK	-	-	C	-	-	-	Berberine and berberine like
IOPMGPNG_00920	5.14e-91	ygaK	-	-	C	-	-	-	Berberine and berberine like
IOPMGPNG_00922	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IOPMGPNG_00923	9.01e-179	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IOPMGPNG_00924	4.19e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
IOPMGPNG_00925	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOPMGPNG_00926	2.68e-275	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
IOPMGPNG_00928	5.64e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOPMGPNG_00929	9.35e-101	ygaO	-	-	-	-	-	-	-
IOPMGPNG_00930	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_00932	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
IOPMGPNG_00933	2.07e-284	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IOPMGPNG_00934	4.79e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
IOPMGPNG_00935	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOPMGPNG_00936	2.29e-141	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
IOPMGPNG_00937	1.08e-94	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IOPMGPNG_00938	7.04e-104	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IOPMGPNG_00939	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
IOPMGPNG_00940	3.46e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
IOPMGPNG_00941	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IOPMGPNG_00942	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
IOPMGPNG_00943	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IOPMGPNG_00944	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
IOPMGPNG_00945	1.61e-58	yhcC	-	-	-	-	-	-	-
IOPMGPNG_00946	3.62e-70	-	-	-	-	-	-	-	-
IOPMGPNG_00947	4.78e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_00948	3.79e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_00949	1.25e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_00950	9.87e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOPMGPNG_00951	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IOPMGPNG_00952	2.49e-191	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IOPMGPNG_00953	2.88e-250	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
IOPMGPNG_00954	1.51e-300	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOPMGPNG_00955	1.46e-76	yhcM	-	-	-	-	-	-	-
IOPMGPNG_00956	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOPMGPNG_00957	9.33e-226	yhcP	-	-	-	-	-	-	-
IOPMGPNG_00958	2.29e-144	yhcQ	-	-	M	-	-	-	Spore coat protein
IOPMGPNG_00959	4.29e-156	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOPMGPNG_00960	3.76e-171	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOPMGPNG_00961	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOPMGPNG_00962	7.24e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IOPMGPNG_00963	4.78e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IOPMGPNG_00964	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
IOPMGPNG_00965	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IOPMGPNG_00966	6.14e-155	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
IOPMGPNG_00967	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOPMGPNG_00968	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOPMGPNG_00969	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IOPMGPNG_00970	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IOPMGPNG_00971	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOPMGPNG_00972	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IOPMGPNG_00973	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IOPMGPNG_00974	2.98e-269	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_00975	3.02e-141	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_00976	1.63e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
IOPMGPNG_00977	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
IOPMGPNG_00978	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IOPMGPNG_00979	1.16e-270	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IOPMGPNG_00980	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
IOPMGPNG_00981	2.5e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
IOPMGPNG_00982	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
IOPMGPNG_00983	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IOPMGPNG_00984	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IOPMGPNG_00985	1.65e-208	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_00986	1.3e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IOPMGPNG_00987	5.74e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_00988	3.58e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
IOPMGPNG_00989	2.89e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOPMGPNG_00990	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOPMGPNG_00991	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_00992	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
IOPMGPNG_00993	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
IOPMGPNG_00994	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_00995	6.74e-244	yhdN	-	-	C	-	-	-	Aldo keto reductase
IOPMGPNG_00996	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOPMGPNG_00997	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOPMGPNG_00998	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
IOPMGPNG_00999	4.19e-283	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IOPMGPNG_01000	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOPMGPNG_01001	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOPMGPNG_01002	3.38e-86	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOPMGPNG_01003	1.56e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOPMGPNG_01004	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
IOPMGPNG_01005	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
IOPMGPNG_01006	1.98e-178	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IOPMGPNG_01007	4.49e-197	nodB1	-	-	G	-	-	-	deacetylase
IOPMGPNG_01008	3.16e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IOPMGPNG_01009	1.47e-302	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IOPMGPNG_01010	3.69e-107	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOPMGPNG_01011	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOPMGPNG_01012	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOPMGPNG_01013	3.31e-143	yheG	-	-	GM	-	-	-	NAD(P)H-binding
IOPMGPNG_01014	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IOPMGPNG_01015	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
IOPMGPNG_01016	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IOPMGPNG_01017	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IOPMGPNG_01018	1.39e-247	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
IOPMGPNG_01019	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IOPMGPNG_01020	8.03e-256	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IOPMGPNG_01021	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IOPMGPNG_01022	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
IOPMGPNG_01023	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
IOPMGPNG_01024	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IOPMGPNG_01026	3.23e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
IOPMGPNG_01027	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
IOPMGPNG_01028	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_01029	4.22e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
IOPMGPNG_01030	4.3e-297	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
IOPMGPNG_01031	0.0	yhaN	-	-	L	-	-	-	AAA domain
IOPMGPNG_01032	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
IOPMGPNG_01033	5.39e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
IOPMGPNG_01034	2.35e-163	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOPMGPNG_01035	9.47e-115	yhaK	-	-	S	-	-	-	Putative zincin peptidase
IOPMGPNG_01036	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
IOPMGPNG_01037	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
IOPMGPNG_01038	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
IOPMGPNG_01039	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
IOPMGPNG_01040	7.19e-260	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOPMGPNG_01041	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IOPMGPNG_01042	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
IOPMGPNG_01043	5.15e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IOPMGPNG_01044	5.36e-157	ecsC	-	-	S	-	-	-	EcsC protein family
IOPMGPNG_01045	1.48e-289	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IOPMGPNG_01046	2.21e-311	yhfA	-	-	C	-	-	-	membrane
IOPMGPNG_01047	2.33e-45	-	-	-	C	-	-	-	Rubrerythrin
IOPMGPNG_01048	5.35e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IOPMGPNG_01049	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOPMGPNG_01050	2.14e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IOPMGPNG_01051	2.81e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IOPMGPNG_01052	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IOPMGPNG_01053	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01054	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
IOPMGPNG_01055	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOPMGPNG_01056	1.88e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IOPMGPNG_01057	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
IOPMGPNG_01058	1.07e-93	-	-	-	S	-	-	-	ASCH
IOPMGPNG_01059	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOPMGPNG_01060	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IOPMGPNG_01061	3.34e-244	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IOPMGPNG_01062	8.67e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
IOPMGPNG_01063	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IOPMGPNG_01064	2.78e-85	yhfM	-	-	-	-	-	-	-
IOPMGPNG_01065	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
IOPMGPNG_01066	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOPMGPNG_01067	2.54e-101	-	-	-	K	-	-	-	acetyltransferase
IOPMGPNG_01068	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
IOPMGPNG_01069	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IOPMGPNG_01070	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IOPMGPNG_01071	2.46e-249	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IOPMGPNG_01072	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IOPMGPNG_01073	2.44e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IOPMGPNG_01074	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
IOPMGPNG_01075	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IOPMGPNG_01076	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_01077	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
IOPMGPNG_01078	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
IOPMGPNG_01079	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_01080	5e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
IOPMGPNG_01081	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOPMGPNG_01082	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IOPMGPNG_01083	4.13e-78	yhjD	-	-	-	-	-	-	-
IOPMGPNG_01084	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
IOPMGPNG_01085	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOPMGPNG_01086	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
IOPMGPNG_01087	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_01088	6.03e-271	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
IOPMGPNG_01089	2.3e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IOPMGPNG_01090	1.25e-203	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
IOPMGPNG_01091	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IOPMGPNG_01092	5.09e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_01093	2.5e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
IOPMGPNG_01094	8.2e-269	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IOPMGPNG_01095	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
IOPMGPNG_01096	2.42e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
IOPMGPNG_01097	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
IOPMGPNG_01098	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IOPMGPNG_01099	1.2e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOPMGPNG_01100	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
IOPMGPNG_01101	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
IOPMGPNG_01102	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
IOPMGPNG_01103	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
IOPMGPNG_01104	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
IOPMGPNG_01105	2.88e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
IOPMGPNG_01106	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
IOPMGPNG_01107	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
IOPMGPNG_01108	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IOPMGPNG_01109	4.62e-223	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IOPMGPNG_01110	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IOPMGPNG_01111	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
IOPMGPNG_01112	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOPMGPNG_01113	3.68e-132	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
IOPMGPNG_01114	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOPMGPNG_01115	3.6e-113	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
IOPMGPNG_01116	6.82e-193	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
IOPMGPNG_01117	5.86e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
IOPMGPNG_01118	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_01119	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IOPMGPNG_01120	6.03e-248	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IOPMGPNG_01121	2.44e-120	yisT	-	-	S	-	-	-	DinB family
IOPMGPNG_01122	1.28e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
IOPMGPNG_01123	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOPMGPNG_01124	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
IOPMGPNG_01125	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOPMGPNG_01126	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IOPMGPNG_01127	7.62e-293	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IOPMGPNG_01128	3.87e-184	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IOPMGPNG_01129	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
IOPMGPNG_01130	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
IOPMGPNG_01131	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOPMGPNG_01132	9.36e-278	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOPMGPNG_01133	3.37e-290	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_01134	1.4e-200	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_01135	5.09e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_01136	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IOPMGPNG_01137	1.06e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
IOPMGPNG_01138	1.94e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
IOPMGPNG_01139	4.16e-122	-	-	-	-	-	-	-	-
IOPMGPNG_01140	1.42e-218	-	-	-	-	-	-	-	-
IOPMGPNG_01141	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IOPMGPNG_01142	1.2e-76	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOPMGPNG_01143	6.11e-120	-	-	-	-	-	-	-	-
IOPMGPNG_01144	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
IOPMGPNG_01145	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IOPMGPNG_01146	3.72e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01147	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOPMGPNG_01148	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
IOPMGPNG_01149	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
IOPMGPNG_01150	1.92e-08	-	-	-	-	-	-	-	-
IOPMGPNG_01151	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IOPMGPNG_01152	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IOPMGPNG_01153	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
IOPMGPNG_01154	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
IOPMGPNG_01155	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IOPMGPNG_01156	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IOPMGPNG_01157	7.11e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOPMGPNG_01158	8.64e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOPMGPNG_01159	1.27e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IOPMGPNG_01160	1.62e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IOPMGPNG_01161	3.3e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IOPMGPNG_01162	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
IOPMGPNG_01163	4.27e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOPMGPNG_01164	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
IOPMGPNG_01165	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IOPMGPNG_01166	1.4e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
IOPMGPNG_01167	5.2e-132	yjaV	-	-	-	-	-	-	-
IOPMGPNG_01168	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
IOPMGPNG_01169	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
IOPMGPNG_01170	2.67e-38	yjzB	-	-	-	-	-	-	-
IOPMGPNG_01171	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOPMGPNG_01172	1.02e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOPMGPNG_01173	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
IOPMGPNG_01174	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_01175	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_01176	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
IOPMGPNG_01177	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOPMGPNG_01178	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOPMGPNG_01179	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
IOPMGPNG_01180	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IOPMGPNG_01181	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOPMGPNG_01182	4.19e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOPMGPNG_01183	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOPMGPNG_01184	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_01185	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_01186	8.67e-270	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOPMGPNG_01187	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_01188	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOPMGPNG_01189	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
IOPMGPNG_01190	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOPMGPNG_01191	2.23e-275	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IOPMGPNG_01192	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IOPMGPNG_01193	2.68e-28	-	-	-	-	-	-	-	-
IOPMGPNG_01195	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IOPMGPNG_01196	1.43e-92	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
IOPMGPNG_01197	3.42e-127	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOPMGPNG_01198	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01199	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
IOPMGPNG_01200	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
IOPMGPNG_01201	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOPMGPNG_01202	2.12e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IOPMGPNG_01203	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IOPMGPNG_01204	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOPMGPNG_01205	1.15e-176	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOPMGPNG_01206	1.34e-137	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
IOPMGPNG_01207	8.96e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
IOPMGPNG_01208	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
IOPMGPNG_01209	2.76e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOPMGPNG_01210	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOPMGPNG_01211	1.97e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOPMGPNG_01212	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IOPMGPNG_01213	2.31e-100	yjbX	-	-	S	-	-	-	Spore coat protein
IOPMGPNG_01214	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
IOPMGPNG_01215	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
IOPMGPNG_01216	1.23e-95	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
IOPMGPNG_01217	9.3e-32	cotW	-	-	-	ko:K06341	-	ko00000	-
IOPMGPNG_01218	6.69e-66	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
IOPMGPNG_01219	5.03e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IOPMGPNG_01222	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
IOPMGPNG_01223	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOPMGPNG_01224	6.31e-51	-	-	-	-	-	-	-	-
IOPMGPNG_01225	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_01226	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
IOPMGPNG_01227	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
IOPMGPNG_01228	1.14e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOPMGPNG_01229	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOPMGPNG_01230	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
IOPMGPNG_01231	2.47e-272	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
IOPMGPNG_01233	6.99e-65	-	-	-	-	-	-	-	-
IOPMGPNG_01234	1.34e-273	-	-	-	S	-	-	-	Bacterial EndoU nuclease
IOPMGPNG_01239	4.75e-38	-	-	-	K	-	-	-	Helix-turn-helix domain
IOPMGPNG_01247	7.57e-269	-	-	-	S	-	-	-	Putative amidase domain
IOPMGPNG_01248	1.47e-66	yjcN	-	-	-	-	-	-	-
IOPMGPNG_01249	1.99e-64	yqaS	-	-	L	-	-	-	DNA packaging
IOPMGPNG_01250	1.27e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IOPMGPNG_01251	2.81e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_01252	0.000141	-	-	-	-	-	-	-	-
IOPMGPNG_01253	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
IOPMGPNG_01254	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_01255	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOPMGPNG_01256	6.5e-76	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
IOPMGPNG_01257	3.75e-119	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOPMGPNG_01259	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOPMGPNG_01260	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
IOPMGPNG_01261	9.41e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
IOPMGPNG_01262	2.16e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOPMGPNG_01264	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IOPMGPNG_01265	6.11e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
IOPMGPNG_01266	4.62e-29	yjfB	-	-	S	-	-	-	Putative motility protein
IOPMGPNG_01267	1.52e-208	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IOPMGPNG_01268	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
IOPMGPNG_01269	4.76e-131	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
IOPMGPNG_01270	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IOPMGPNG_01271	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IOPMGPNG_01273	9.09e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IOPMGPNG_01275	7.52e-283	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOPMGPNG_01276	1.14e-275	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOPMGPNG_01277	1.11e-41	-	-	-	-	-	-	-	-
IOPMGPNG_01278	2.05e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IOPMGPNG_01279	7.42e-155	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IOPMGPNG_01280	2.3e-174	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IOPMGPNG_01281	3.12e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
IOPMGPNG_01282	1.22e-118	yjlB	-	-	S	-	-	-	Cupin domain
IOPMGPNG_01283	3.98e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IOPMGPNG_01284	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOPMGPNG_01285	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IOPMGPNG_01286	3.4e-311	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IOPMGPNG_01287	4.91e-240	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
IOPMGPNG_01288	6.98e-241	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IOPMGPNG_01289	2.76e-273	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IOPMGPNG_01290	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_01291	7.93e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
IOPMGPNG_01292	4.02e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IOPMGPNG_01293	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IOPMGPNG_01294	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IOPMGPNG_01295	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOPMGPNG_01296	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
IOPMGPNG_01297	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
IOPMGPNG_01298	2.87e-270	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOPMGPNG_01300	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
IOPMGPNG_01301	2.65e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOPMGPNG_01302	3.87e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
IOPMGPNG_01303	9.75e-76	yjqB	-	-	S	-	-	-	Pfam:DUF867
IOPMGPNG_01304	3.73e-203	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
IOPMGPNG_01305	7.01e-141	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IOPMGPNG_01306	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOPMGPNG_01308	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
IOPMGPNG_01309	2.91e-150	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
IOPMGPNG_01313	3.31e-109	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IOPMGPNG_01314	6.51e-177	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
IOPMGPNG_01315	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IOPMGPNG_01316	0.0	yqbA	-	-	S	-	-	-	portal protein
IOPMGPNG_01317	1.99e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
IOPMGPNG_01318	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
IOPMGPNG_01319	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IOPMGPNG_01320	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IOPMGPNG_01321	2.38e-114	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IOPMGPNG_01322	2.87e-101	xkdJ	-	-	-	-	-	-	-
IOPMGPNG_01323	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IOPMGPNG_01324	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
IOPMGPNG_01325	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IOPMGPNG_01326	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IOPMGPNG_01327	5.92e-157	xkdP	-	-	S	-	-	-	Lysin motif
IOPMGPNG_01328	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
IOPMGPNG_01329	6.14e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IOPMGPNG_01330	2.69e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IOPMGPNG_01331	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IOPMGPNG_01332	7.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IOPMGPNG_01333	5.18e-55	-	-	-	-	-	-	-	-
IOPMGPNG_01334	0.0	-	-	-	-	-	-	-	-
IOPMGPNG_01335	1.39e-70	xkdW	-	-	S	-	-	-	XkdW protein
IOPMGPNG_01336	7.71e-32	xkdX	-	-	-	-	-	-	-
IOPMGPNG_01337	2.81e-194	xepA	-	-	-	-	-	-	-
IOPMGPNG_01338	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IOPMGPNG_01339	3.87e-51	xhlB	-	-	S	-	-	-	SPP1 phage holin
IOPMGPNG_01340	1.85e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IOPMGPNG_01342	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
IOPMGPNG_01343	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
IOPMGPNG_01344	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IOPMGPNG_01345	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
IOPMGPNG_01346	1.49e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IOPMGPNG_01347	6.63e-232	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IOPMGPNG_01348	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOPMGPNG_01349	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOPMGPNG_01351	1.92e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOPMGPNG_01352	1.16e-178	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
IOPMGPNG_01353	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IOPMGPNG_01354	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOPMGPNG_01355	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOPMGPNG_01356	1.35e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_01357	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IOPMGPNG_01359	4.26e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IOPMGPNG_01360	1.24e-259	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IOPMGPNG_01361	2.56e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOPMGPNG_01362	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_01363	8.08e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
IOPMGPNG_01364	9.87e-203	ykgA	-	-	E	-	-	-	Amidinotransferase
IOPMGPNG_01365	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
IOPMGPNG_01366	7.29e-287	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IOPMGPNG_01367	1.96e-08	-	-	-	-	-	-	-	-
IOPMGPNG_01368	3.95e-167	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IOPMGPNG_01369	1.29e-127	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
IOPMGPNG_01370	7.48e-87	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOPMGPNG_01371	1.22e-20	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOPMGPNG_01372	1.8e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IOPMGPNG_01373	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IOPMGPNG_01374	3.22e-215	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IOPMGPNG_01375	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOPMGPNG_01376	1.26e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOPMGPNG_01377	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IOPMGPNG_01378	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
IOPMGPNG_01379	3.32e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IOPMGPNG_01380	1.76e-109	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
IOPMGPNG_01381	5.96e-83	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IOPMGPNG_01382	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOPMGPNG_01383	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOPMGPNG_01384	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOPMGPNG_01385	3e-172	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IOPMGPNG_01386	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_01387	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IOPMGPNG_01388	1.21e-142	ykoF	-	-	S	-	-	-	YKOF-related Family
IOPMGPNG_01389	5.02e-158	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_01390	8.94e-307	ykoH	-	-	T	-	-	-	Histidine kinase
IOPMGPNG_01391	5.32e-143	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IOPMGPNG_01392	7.2e-109	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IOPMGPNG_01393	1.45e-08	-	-	-	-	-	-	-	-
IOPMGPNG_01395	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IOPMGPNG_01396	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
IOPMGPNG_01397	1.63e-25	-	-	-	-	-	-	-	-
IOPMGPNG_01398	3.04e-36	ykoL	-	-	-	-	-	-	-
IOPMGPNG_01399	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IOPMGPNG_01400	2.62e-269	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IOPMGPNG_01401	2.48e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
IOPMGPNG_01402	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IOPMGPNG_01403	0.0	ykoS	-	-	-	-	-	-	-
IOPMGPNG_01404	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOPMGPNG_01405	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
IOPMGPNG_01406	1.78e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IOPMGPNG_01407	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IOPMGPNG_01408	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
IOPMGPNG_01409	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IOPMGPNG_01410	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_01411	2.56e-209	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
IOPMGPNG_01412	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
IOPMGPNG_01413	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
IOPMGPNG_01414	2.29e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IOPMGPNG_01415	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
IOPMGPNG_01417	1.77e-28	ykzE	-	-	-	-	-	-	-
IOPMGPNG_01418	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
IOPMGPNG_01419	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_01420	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOPMGPNG_01422	1.55e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IOPMGPNG_01423	1.37e-290	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IOPMGPNG_01424	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOPMGPNG_01425	2.67e-293	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOPMGPNG_01426	3.79e-292	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IOPMGPNG_01427	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IOPMGPNG_01428	1.51e-145	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IOPMGPNG_01429	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IOPMGPNG_01430	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IOPMGPNG_01432	5.62e-93	eag	-	-	-	-	-	-	-
IOPMGPNG_01433	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IOPMGPNG_01434	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IOPMGPNG_01435	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IOPMGPNG_01436	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IOPMGPNG_01437	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IOPMGPNG_01438	6.76e-227	ykvI	-	-	S	-	-	-	membrane
IOPMGPNG_01439	1.11e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IOPMGPNG_01440	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IOPMGPNG_01441	2.06e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IOPMGPNG_01442	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IOPMGPNG_01443	7.06e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IOPMGPNG_01444	1.89e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_01445	1.43e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
IOPMGPNG_01446	3.95e-39	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
IOPMGPNG_01447	7.12e-204	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
IOPMGPNG_01448	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
IOPMGPNG_01449	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01450	2.6e-39	-	-	-	-	-	-	-	-
IOPMGPNG_01451	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
IOPMGPNG_01452	6.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOPMGPNG_01453	2.76e-115	stoA	-	-	CO	-	-	-	thiol-disulfide
IOPMGPNG_01454	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IOPMGPNG_01455	1.11e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IOPMGPNG_01456	2.69e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_01457	1.39e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IOPMGPNG_01458	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_01459	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
IOPMGPNG_01460	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOPMGPNG_01461	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01462	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
IOPMGPNG_01463	1.06e-167	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_01464	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_01465	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IOPMGPNG_01466	5.36e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
IOPMGPNG_01467	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOPMGPNG_01468	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_01469	1.99e-281	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IOPMGPNG_01470	1.05e-22	-	-	-	-	-	-	-	-
IOPMGPNG_01471	2.02e-215	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
IOPMGPNG_01472	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
IOPMGPNG_01473	2.97e-304	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_01474	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01475	2.45e-210	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
IOPMGPNG_01476	2.91e-179	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_01477	1.02e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
IOPMGPNG_01478	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01479	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
IOPMGPNG_01480	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
IOPMGPNG_01481	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
IOPMGPNG_01482	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_01483	7.13e-110	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
IOPMGPNG_01484	1.81e-224	ykuO	-	-	-	-	-	-	-
IOPMGPNG_01485	1.03e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IOPMGPNG_01486	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOPMGPNG_01487	7.66e-274	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOPMGPNG_01488	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
IOPMGPNG_01489	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
IOPMGPNG_01490	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
IOPMGPNG_01491	2.45e-103	ykuV	-	-	CO	-	-	-	thiol-disulfide
IOPMGPNG_01492	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
IOPMGPNG_01493	6.97e-200	yknT	-	-	-	ko:K06437	-	ko00000	-
IOPMGPNG_01494	1.53e-140	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IOPMGPNG_01495	1.26e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOPMGPNG_01496	4.29e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
IOPMGPNG_01497	6.67e-120	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IOPMGPNG_01498	1.1e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
IOPMGPNG_01499	3.3e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IOPMGPNG_01500	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOPMGPNG_01501	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IOPMGPNG_01502	1.26e-148	yknW	-	-	S	-	-	-	Yip1 domain
IOPMGPNG_01503	9.95e-235	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOPMGPNG_01504	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_01505	1.72e-268	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IOPMGPNG_01506	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01507	8.21e-215	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
IOPMGPNG_01508	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IOPMGPNG_01509	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOPMGPNG_01510	5.43e-52	ykoA	-	-	-	-	-	-	-
IOPMGPNG_01511	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOPMGPNG_01512	1.3e-211	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOPMGPNG_01513	4.19e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IOPMGPNG_01514	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
IOPMGPNG_01515	2.51e-233	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
IOPMGPNG_01516	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
IOPMGPNG_01517	1.87e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IOPMGPNG_01518	9.21e-208	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
IOPMGPNG_01519	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IOPMGPNG_01520	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IOPMGPNG_01521	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOPMGPNG_01522	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IOPMGPNG_01523	2.03e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
IOPMGPNG_01524	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOPMGPNG_01525	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IOPMGPNG_01526	3.68e-139	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
IOPMGPNG_01527	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOPMGPNG_01528	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOPMGPNG_01529	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOPMGPNG_01530	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOPMGPNG_01531	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IOPMGPNG_01532	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
IOPMGPNG_01533	2.22e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IOPMGPNG_01534	3.57e-150	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IOPMGPNG_01535	4.48e-35	ykzI	-	-	-	-	-	-	-
IOPMGPNG_01536	1.57e-193	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
IOPMGPNG_01537	2.86e-98	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IOPMGPNG_01538	9.64e-219	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IOPMGPNG_01539	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IOPMGPNG_01540	0.0	ylaA	-	-	-	-	-	-	-
IOPMGPNG_01541	1.44e-56	ylaB	-	-	-	-	-	-	-
IOPMGPNG_01542	3.56e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_01544	4.02e-56	ylaE	-	-	-	-	-	-	-
IOPMGPNG_01545	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
IOPMGPNG_01546	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IOPMGPNG_01547	1.79e-62	ylaH	-	-	S	-	-	-	YlaH-like protein
IOPMGPNG_01548	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01549	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOPMGPNG_01550	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
IOPMGPNG_01551	3.8e-111	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IOPMGPNG_01552	2.46e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IOPMGPNG_01553	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
IOPMGPNG_01554	3.65e-273	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOPMGPNG_01555	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOPMGPNG_01556	1.65e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IOPMGPNG_01557	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOPMGPNG_01558	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IOPMGPNG_01559	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOPMGPNG_01560	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IOPMGPNG_01561	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IOPMGPNG_01562	2.98e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
IOPMGPNG_01563	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
IOPMGPNG_01564	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IOPMGPNG_01565	1.53e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
IOPMGPNG_01566	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
IOPMGPNG_01567	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
IOPMGPNG_01568	6.72e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IOPMGPNG_01569	5.1e-51	ylbG	-	-	S	-	-	-	UPF0298 protein
IOPMGPNG_01570	8.27e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IOPMGPNG_01571	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOPMGPNG_01572	5.5e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
IOPMGPNG_01573	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IOPMGPNG_01574	2.24e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IOPMGPNG_01575	4.88e-300	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IOPMGPNG_01577	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IOPMGPNG_01578	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IOPMGPNG_01579	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IOPMGPNG_01580	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
IOPMGPNG_01581	5.56e-215	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOPMGPNG_01582	1.34e-09	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IOPMGPNG_01583	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IOPMGPNG_01584	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IOPMGPNG_01585	1.94e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOPMGPNG_01586	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
IOPMGPNG_01587	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IOPMGPNG_01588	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
IOPMGPNG_01589	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOPMGPNG_01590	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOPMGPNG_01591	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOPMGPNG_01592	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IOPMGPNG_01593	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOPMGPNG_01594	9.18e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IOPMGPNG_01595	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOPMGPNG_01596	4.5e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01597	1.2e-122	ylxX	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01598	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
IOPMGPNG_01599	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOPMGPNG_01600	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOPMGPNG_01601	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IOPMGPNG_01602	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IOPMGPNG_01603	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_01604	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_01605	5.24e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IOPMGPNG_01606	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IOPMGPNG_01607	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
IOPMGPNG_01608	2.16e-202	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
IOPMGPNG_01609	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOPMGPNG_01610	1.28e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOPMGPNG_01611	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
IOPMGPNG_01612	1.49e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IOPMGPNG_01613	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IOPMGPNG_01614	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOPMGPNG_01615	3.74e-82	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IOPMGPNG_01616	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOPMGPNG_01617	2.9e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IOPMGPNG_01618	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOPMGPNG_01619	7.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
IOPMGPNG_01620	7.29e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IOPMGPNG_01621	2.91e-316	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOPMGPNG_01622	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IOPMGPNG_01623	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
IOPMGPNG_01624	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IOPMGPNG_01625	2.2e-223	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOPMGPNG_01626	3.8e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOPMGPNG_01627	1.22e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOPMGPNG_01629	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IOPMGPNG_01630	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
IOPMGPNG_01631	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IOPMGPNG_01632	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IOPMGPNG_01633	3.56e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IOPMGPNG_01634	1.97e-185	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
IOPMGPNG_01635	3.78e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
IOPMGPNG_01636	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IOPMGPNG_01637	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
IOPMGPNG_01638	6.91e-201	yloC	-	-	S	-	-	-	stress-induced protein
IOPMGPNG_01639	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
IOPMGPNG_01640	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IOPMGPNG_01641	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOPMGPNG_01642	7.28e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOPMGPNG_01643	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOPMGPNG_01644	8.3e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOPMGPNG_01645	1.28e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOPMGPNG_01646	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOPMGPNG_01647	5.3e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOPMGPNG_01648	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IOPMGPNG_01649	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IOPMGPNG_01650	3.92e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOPMGPNG_01651	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IOPMGPNG_01652	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IOPMGPNG_01653	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IOPMGPNG_01654	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_01655	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IOPMGPNG_01656	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IOPMGPNG_01657	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IOPMGPNG_01658	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOPMGPNG_01659	4.52e-118	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IOPMGPNG_01660	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOPMGPNG_01661	3.09e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IOPMGPNG_01662	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IOPMGPNG_01663	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOPMGPNG_01664	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOPMGPNG_01665	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IOPMGPNG_01666	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOPMGPNG_01667	1.67e-114	-	-	-	-	-	-	-	-
IOPMGPNG_01668	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOPMGPNG_01669	1.96e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOPMGPNG_01670	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IOPMGPNG_01671	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IOPMGPNG_01672	2.3e-78	ylqD	-	-	S	-	-	-	YlqD protein
IOPMGPNG_01673	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOPMGPNG_01674	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IOPMGPNG_01675	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOPMGPNG_01676	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOPMGPNG_01677	1.18e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOPMGPNG_01678	0.0	ylqG	-	-	-	-	-	-	-
IOPMGPNG_01679	6.94e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
IOPMGPNG_01680	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOPMGPNG_01681	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOPMGPNG_01682	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
IOPMGPNG_01683	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOPMGPNG_01684	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOPMGPNG_01685	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
IOPMGPNG_01686	2.12e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOPMGPNG_01687	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOPMGPNG_01688	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IOPMGPNG_01689	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IOPMGPNG_01690	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
IOPMGPNG_01691	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
IOPMGPNG_01692	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
IOPMGPNG_01693	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOPMGPNG_01694	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
IOPMGPNG_01695	1.22e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IOPMGPNG_01696	7.27e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
IOPMGPNG_01697	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
IOPMGPNG_01698	1.28e-311	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
IOPMGPNG_01699	3.99e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
IOPMGPNG_01700	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
IOPMGPNG_01701	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
IOPMGPNG_01702	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOPMGPNG_01703	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IOPMGPNG_01704	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
IOPMGPNG_01705	1.12e-136	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
IOPMGPNG_01706	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
IOPMGPNG_01707	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
IOPMGPNG_01708	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
IOPMGPNG_01709	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOPMGPNG_01710	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOPMGPNG_01711	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
IOPMGPNG_01712	6.33e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
IOPMGPNG_01713	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IOPMGPNG_01714	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
IOPMGPNG_01715	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
IOPMGPNG_01716	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IOPMGPNG_01717	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IOPMGPNG_01718	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_01719	9.41e-99	ylxL	-	-	-	-	-	-	-
IOPMGPNG_01720	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IOPMGPNG_01721	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOPMGPNG_01722	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IOPMGPNG_01723	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOPMGPNG_01724	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOPMGPNG_01725	1.36e-177	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IOPMGPNG_01726	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOPMGPNG_01727	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IOPMGPNG_01728	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOPMGPNG_01729	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOPMGPNG_01730	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IOPMGPNG_01731	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IOPMGPNG_01732	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
IOPMGPNG_01733	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
IOPMGPNG_01734	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOPMGPNG_01735	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
IOPMGPNG_01736	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOPMGPNG_01737	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOPMGPNG_01738	1.34e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IOPMGPNG_01739	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOPMGPNG_01740	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOPMGPNG_01741	3.71e-235	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
IOPMGPNG_01742	6.59e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
IOPMGPNG_01743	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
IOPMGPNG_01744	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
IOPMGPNG_01745	9.94e-142	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IOPMGPNG_01746	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOPMGPNG_01747	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOPMGPNG_01748	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOPMGPNG_01749	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOPMGPNG_01750	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
IOPMGPNG_01751	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
IOPMGPNG_01752	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOPMGPNG_01753	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01754	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_01755	3.31e-299	albE	-	-	S	-	-	-	Peptidase M16
IOPMGPNG_01756	6.8e-309	ymfH	-	-	S	-	-	-	zinc protease
IOPMGPNG_01757	1.49e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IOPMGPNG_01758	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IOPMGPNG_01759	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
IOPMGPNG_01760	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
IOPMGPNG_01761	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOPMGPNG_01762	3.05e-299	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IOPMGPNG_01763	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOPMGPNG_01764	4e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
IOPMGPNG_01765	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IOPMGPNG_01766	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
IOPMGPNG_01767	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
IOPMGPNG_01768	2.04e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IOPMGPNG_01769	5.89e-278	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOPMGPNG_01770	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOPMGPNG_01771	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IOPMGPNG_01772	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
IOPMGPNG_01773	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOPMGPNG_01774	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOPMGPNG_01775	3.04e-88	-	-	-	S	-	-	-	Regulatory protein YrvL
IOPMGPNG_01777	7.96e-127	ymcC	-	-	S	-	-	-	Membrane
IOPMGPNG_01778	3.43e-140	pksA	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_01779	4.02e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
IOPMGPNG_01780	4.37e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IOPMGPNG_01782	1.64e-236	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
IOPMGPNG_01783	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IOPMGPNG_01784	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
IOPMGPNG_01785	1.78e-302	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOPMGPNG_01786	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
IOPMGPNG_01787	1.01e-183	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
IOPMGPNG_01788	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
IOPMGPNG_01789	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IOPMGPNG_01790	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
IOPMGPNG_01791	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IOPMGPNG_01792	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
IOPMGPNG_01793	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
IOPMGPNG_01794	1.44e-296	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOPMGPNG_01795	2.8e-81	ymzB	-	-	-	-	-	-	-
IOPMGPNG_01796	4.8e-210	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IOPMGPNG_01797	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
IOPMGPNG_01799	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
IOPMGPNG_01800	4.53e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
IOPMGPNG_01801	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
IOPMGPNG_01802	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IOPMGPNG_01804	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
IOPMGPNG_01805	5.61e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOPMGPNG_01806	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IOPMGPNG_01807	1.63e-31	-	-	-	-	-	-	-	-
IOPMGPNG_01808	1.2e-30	ymzA	-	-	-	-	-	-	-
IOPMGPNG_01809	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IOPMGPNG_01810	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOPMGPNG_01811	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOPMGPNG_01812	2.24e-141	-	-	-	-	-	-	-	-
IOPMGPNG_01813	4.04e-150	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IOPMGPNG_01814	1.33e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
IOPMGPNG_01815	1.49e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOPMGPNG_01816	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IOPMGPNG_01817	2.85e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
IOPMGPNG_01818	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IOPMGPNG_01819	2.95e-14	-	-	-	-	-	-	-	-
IOPMGPNG_01822	6.76e-120	-	-	-	M	-	-	-	Glycosyltransferase like family
IOPMGPNG_01823	1.17e-155	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
IOPMGPNG_01824	6.07e-248	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOPMGPNG_01825	1.81e-273	-	-	-	H	-	-	-	N-terminal domain of galactosyltransferase
IOPMGPNG_01827	2.9e-126	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_01829	2.82e-94	-	-	-	S	-	-	-	CAAX protease self-immunity
IOPMGPNG_01832	9.78e-107	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
IOPMGPNG_01833	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IOPMGPNG_01834	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOPMGPNG_01835	2.13e-276	xylR	-	-	GK	-	-	-	ROK family
IOPMGPNG_01836	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IOPMGPNG_01837	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
IOPMGPNG_01838	2.51e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
IOPMGPNG_01839	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOPMGPNG_01840	1.77e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOPMGPNG_01841	9.48e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
IOPMGPNG_01842	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
IOPMGPNG_01845	2.75e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOPMGPNG_01846	8.27e-40	-	-	-	-	-	-	-	-
IOPMGPNG_01848	3.99e-163	-	-	-	S	-	-	-	Domain of unknown function, YrpD
IOPMGPNG_01851	1.96e-33	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
IOPMGPNG_01852	8.92e-96	-	-	-	-	-	-	-	-
IOPMGPNG_01853	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
IOPMGPNG_01856	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IOPMGPNG_01857	1.53e-247	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
IOPMGPNG_01858	1.6e-288	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IOPMGPNG_01859	1.52e-197	yndG	-	-	S	-	-	-	DoxX-like family
IOPMGPNG_01860	4.21e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
IOPMGPNG_01861	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
IOPMGPNG_01863	8.59e-171	yndL	-	-	S	-	-	-	Replication protein
IOPMGPNG_01864	3.11e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IOPMGPNG_01865	3.01e-102	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IOPMGPNG_01866	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOPMGPNG_01867	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IOPMGPNG_01868	1.88e-143	yneB	-	-	L	-	-	-	resolvase
IOPMGPNG_01869	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
IOPMGPNG_01870	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IOPMGPNG_01871	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
IOPMGPNG_01872	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IOPMGPNG_01873	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IOPMGPNG_01874	1.18e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
IOPMGPNG_01875	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IOPMGPNG_01876	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
IOPMGPNG_01877	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
IOPMGPNG_01878	5.77e-85	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
IOPMGPNG_01879	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
IOPMGPNG_01880	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
IOPMGPNG_01881	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOPMGPNG_01882	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IOPMGPNG_01883	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
IOPMGPNG_01885	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
IOPMGPNG_01886	4.02e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IOPMGPNG_01887	4.68e-71	yneQ	-	-	-	-	-	-	-
IOPMGPNG_01888	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IOPMGPNG_01889	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOPMGPNG_01890	3.47e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IOPMGPNG_01891	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOPMGPNG_01892	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOPMGPNG_01893	1.82e-18	-	-	-	-	-	-	-	-
IOPMGPNG_01894	6.15e-75	ynfC	-	-	-	-	-	-	-
IOPMGPNG_01895	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IOPMGPNG_01896	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
IOPMGPNG_01898	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
IOPMGPNG_01899	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IOPMGPNG_01900	2.45e-103	yngA	-	-	S	-	-	-	membrane
IOPMGPNG_01901	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOPMGPNG_01902	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
IOPMGPNG_01903	1.28e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
IOPMGPNG_01904	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOPMGPNG_01905	6.03e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
IOPMGPNG_01906	7.02e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
IOPMGPNG_01907	1.23e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
IOPMGPNG_01908	9.05e-313	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
IOPMGPNG_01909	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOPMGPNG_01910	3.76e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IOPMGPNG_01911	4.3e-41	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
IOPMGPNG_01912	2.97e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IOPMGPNG_01913	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
IOPMGPNG_01914	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IOPMGPNG_01915	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IOPMGPNG_01916	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_01917	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_01918	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_01919	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_01920	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IOPMGPNG_01921	6.44e-239	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IOPMGPNG_01922	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
IOPMGPNG_01923	4.13e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
IOPMGPNG_01925	1.14e-124	-	-	-	L	-	-	-	Integrase
IOPMGPNG_01926	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
IOPMGPNG_01927	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IOPMGPNG_01928	2.93e-199	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01929	2.42e-236	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IOPMGPNG_01930	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IOPMGPNG_01931	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
IOPMGPNG_01932	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01933	1.35e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOPMGPNG_01934	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOPMGPNG_01935	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IOPMGPNG_01936	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_01937	1.15e-54	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IOPMGPNG_01938	1.1e-184	yoxB	-	-	-	-	-	-	-
IOPMGPNG_01939	6.11e-118	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOPMGPNG_01940	1.91e-293	-	-	-	S	-	-	-	Arylsulfotransferase (ASST)
IOPMGPNG_01941	5.31e-148	-	3.1.1.3	-	I	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	Lipase (class 3)
IOPMGPNG_01942	9.19e-159	-	3.1.1.3	-	I	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	Lipase (class 3)
IOPMGPNG_01943	5.04e-297	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
IOPMGPNG_01944	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IOPMGPNG_01945	3.36e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOPMGPNG_01946	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOPMGPNG_01947	2.08e-44	yoaF	-	-	-	-	-	-	-
IOPMGPNG_01949	1.25e-20	-	-	-	-	-	-	-	-
IOPMGPNG_01950	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
IOPMGPNG_01951	2.91e-292	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
IOPMGPNG_01952	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
IOPMGPNG_01953	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
IOPMGPNG_01954	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
IOPMGPNG_01955	5e-253	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IOPMGPNG_01956	2.07e-170	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
IOPMGPNG_01958	9.27e-295	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IOPMGPNG_01960	2.23e-186	yoaP	-	-	K	-	-	-	YoaP-like
IOPMGPNG_01961	8.31e-85	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IOPMGPNG_01962	3.22e-114	-	-	-	-	-	-	-	-
IOPMGPNG_01963	8.56e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
IOPMGPNG_01964	1.6e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IOPMGPNG_01965	7.38e-50	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_01966	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
IOPMGPNG_01967	4.5e-201	yoaU	-	-	K	-	-	-	LysR substrate binding domain
IOPMGPNG_01968	2.14e-200	yoaV	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_01969	5.63e-102	yoaW	-	-	-	-	-	-	-
IOPMGPNG_01970	1.15e-145	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
IOPMGPNG_01971	4.72e-211	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IOPMGPNG_01974	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
IOPMGPNG_01975	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
IOPMGPNG_01976	6.27e-51	-	-	-	S	-	-	-	TM2 domain
IOPMGPNG_01977	5.16e-72	-	-	-	K	-	-	-	Helix-turn-helix
IOPMGPNG_01980	1.69e-102	-	-	-	S	-	-	-	MepB protein
IOPMGPNG_01982	5.14e-151	-	-	-	-	-	-	-	-
IOPMGPNG_01983	2.72e-39	-	-	-	O	-	-	-	Subtilase family
IOPMGPNG_01990	4.74e-38	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
IOPMGPNG_01992	1.43e-80	yoqH	-	-	M	-	-	-	LysM domain
IOPMGPNG_01996	8.49e-265	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IOPMGPNG_01998	1.28e-99	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOPMGPNG_01999	1.06e-33	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOPMGPNG_02000	6.76e-44	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOPMGPNG_02002	7.82e-60	-	-	-	-	-	-	-	-
IOPMGPNG_02004	4.26e-25	-	-	-	-	-	-	-	-
IOPMGPNG_02005	8.94e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOPMGPNG_02006	1.37e-117	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
IOPMGPNG_02007	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
IOPMGPNG_02008	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
IOPMGPNG_02009	8.66e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
IOPMGPNG_02010	1.23e-173	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IOPMGPNG_02011	6.15e-182	-	-	-	J	-	-	-	FR47-like protein
IOPMGPNG_02012	9.22e-129	yobS	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02013	1.83e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOPMGPNG_02014	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IOPMGPNG_02015	1.14e-226	yobV	-	-	K	-	-	-	WYL domain
IOPMGPNG_02016	6.8e-117	yobW	-	-	-	-	-	-	-
IOPMGPNG_02017	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
IOPMGPNG_02018	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOPMGPNG_02019	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
IOPMGPNG_02020	2.6e-185	-	-	-	-	-	-	-	-
IOPMGPNG_02021	1.08e-121	yocC	-	-	-	-	-	-	-
IOPMGPNG_02022	1.29e-214	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
IOPMGPNG_02023	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IOPMGPNG_02024	3.51e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_02025	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_02026	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
IOPMGPNG_02027	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOPMGPNG_02028	2.07e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOPMGPNG_02029	1.17e-106	yocK	-	-	T	-	-	-	general stress protein
IOPMGPNG_02030	4.13e-68	yocL	-	-	-	-	-	-	-
IOPMGPNG_02031	5.79e-43	-	-	-	-	-	-	-	-
IOPMGPNG_02032	1.56e-113	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOPMGPNG_02033	2.94e-55	yozN	-	-	-	-	-	-	-
IOPMGPNG_02034	1.83e-49	yocN	-	-	-	-	-	-	-
IOPMGPNG_02035	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
IOPMGPNG_02036	1.91e-42	yozC	-	-	-	-	-	-	-
IOPMGPNG_02037	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOPMGPNG_02038	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
IOPMGPNG_02039	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
IOPMGPNG_02040	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOPMGPNG_02041	9.48e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
IOPMGPNG_02042	5.23e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IOPMGPNG_02043	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IOPMGPNG_02044	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
IOPMGPNG_02045	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
IOPMGPNG_02046	6.01e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IOPMGPNG_02047	7.5e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IOPMGPNG_02048	2.67e-292	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
IOPMGPNG_02049	4.31e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOPMGPNG_02051	3.41e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IOPMGPNG_02052	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOPMGPNG_02053	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
IOPMGPNG_02054	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
IOPMGPNG_02055	1.85e-58	-	-	-	-	-	-	-	-
IOPMGPNG_02056	5.49e-206	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
IOPMGPNG_02057	5.82e-103	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
IOPMGPNG_02058	1.95e-14	-	-	-	-	-	-	-	-
IOPMGPNG_02059	2.4e-179	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IOPMGPNG_02060	2.18e-90	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IOPMGPNG_02061	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
IOPMGPNG_02062	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
IOPMGPNG_02063	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
IOPMGPNG_02064	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
IOPMGPNG_02065	3.38e-223	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IOPMGPNG_02066	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IOPMGPNG_02067	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOPMGPNG_02068	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IOPMGPNG_02069	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
IOPMGPNG_02070	4.86e-41	yodI	-	-	-	-	-	-	-
IOPMGPNG_02071	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IOPMGPNG_02072	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IOPMGPNG_02073	2.08e-12	-	-	-	-	-	-	-	-
IOPMGPNG_02074	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
IOPMGPNG_02075	4.02e-138	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IOPMGPNG_02076	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
IOPMGPNG_02078	1.29e-159	yodN	-	-	-	-	-	-	-
IOPMGPNG_02079	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IOPMGPNG_02080	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
IOPMGPNG_02081	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
IOPMGPNG_02082	2.06e-194	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IOPMGPNG_02083	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
IOPMGPNG_02084	2.71e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOPMGPNG_02085	3.27e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOPMGPNG_02086	2.34e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOPMGPNG_02088	2.4e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
IOPMGPNG_02089	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
IOPMGPNG_02090	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
IOPMGPNG_02091	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
IOPMGPNG_02092	2.33e-237	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
IOPMGPNG_02093	1.39e-280	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
IOPMGPNG_02094	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IOPMGPNG_02095	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IOPMGPNG_02096	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOPMGPNG_02097	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
IOPMGPNG_02098	4.95e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
IOPMGPNG_02099	6.12e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
IOPMGPNG_02100	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02101	2.12e-177	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOPMGPNG_02102	9.26e-139	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IOPMGPNG_02103	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
IOPMGPNG_02104	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IOPMGPNG_02105	8.1e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02106	4.64e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IOPMGPNG_02107	8.12e-144	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOPMGPNG_02108	9.58e-122	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOPMGPNG_02109	9.52e-199	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOPMGPNG_02110	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IOPMGPNG_02111	1.16e-146	ypjP	-	-	S	-	-	-	YpjP-like protein
IOPMGPNG_02112	3.41e-184	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
IOPMGPNG_02113	1.96e-98	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
IOPMGPNG_02114	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IOPMGPNG_02115	2e-204	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
IOPMGPNG_02116	1.29e-135	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IOPMGPNG_02117	3.01e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IOPMGPNG_02118	6.09e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOPMGPNG_02119	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IOPMGPNG_02120	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IOPMGPNG_02121	1.17e-22	degR	-	-	-	-	-	-	-
IOPMGPNG_02122	1.5e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
IOPMGPNG_02123	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
IOPMGPNG_02124	1.1e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
IOPMGPNG_02125	3.27e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IOPMGPNG_02126	6.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
IOPMGPNG_02127	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
IOPMGPNG_02128	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
IOPMGPNG_02129	1.08e-11	-	-	-	-	-	-	-	-
IOPMGPNG_02130	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
IOPMGPNG_02131	0.0	ypbR	-	-	S	-	-	-	Dynamin family
IOPMGPNG_02132	6.71e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
IOPMGPNG_02133	2.16e-264	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IOPMGPNG_02134	1.22e-291	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IOPMGPNG_02135	2.34e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOPMGPNG_02136	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IOPMGPNG_02137	1.17e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IOPMGPNG_02138	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
IOPMGPNG_02139	1.15e-236	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
IOPMGPNG_02140	8.72e-235	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
IOPMGPNG_02141	3.45e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IOPMGPNG_02142	2.29e-176	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_02143	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
IOPMGPNG_02145	9.5e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IOPMGPNG_02146	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOPMGPNG_02147	3.15e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IOPMGPNG_02148	9.82e-299	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
IOPMGPNG_02149	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IOPMGPNG_02150	6.45e-111	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
IOPMGPNG_02151	1.76e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IOPMGPNG_02152	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
IOPMGPNG_02153	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
IOPMGPNG_02154	5.06e-11	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
IOPMGPNG_02157	5.3e-240	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
IOPMGPNG_02158	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOPMGPNG_02159	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOPMGPNG_02160	1.17e-120	ypoC	-	-	-	-	-	-	-
IOPMGPNG_02161	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOPMGPNG_02162	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
IOPMGPNG_02163	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
IOPMGPNG_02164	1.25e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IOPMGPNG_02165	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02166	3.6e-31	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
IOPMGPNG_02167	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IOPMGPNG_02168	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IOPMGPNG_02169	1.5e-197	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IOPMGPNG_02170	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IOPMGPNG_02171	1.63e-232	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOPMGPNG_02172	1.29e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOPMGPNG_02173	8.54e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
IOPMGPNG_02174	1.1e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
IOPMGPNG_02175	1.52e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
IOPMGPNG_02176	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOPMGPNG_02177	1.67e-72	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
IOPMGPNG_02178	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOPMGPNG_02179	2.29e-181	ypjB	-	-	S	-	-	-	sporulation protein
IOPMGPNG_02180	2.82e-126	ypjA	-	-	S	-	-	-	membrane
IOPMGPNG_02181	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
IOPMGPNG_02182	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
IOPMGPNG_02183	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
IOPMGPNG_02184	1.08e-97	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
IOPMGPNG_02185	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
IOPMGPNG_02186	5.27e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
IOPMGPNG_02187	4.03e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOPMGPNG_02188	8.13e-263	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IOPMGPNG_02189	1.06e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOPMGPNG_02190	2.21e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOPMGPNG_02191	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOPMGPNG_02192	9.07e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IOPMGPNG_02193	5.1e-146	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IOPMGPNG_02194	2.03e-228	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOPMGPNG_02195	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOPMGPNG_02196	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IOPMGPNG_02197	4.7e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOPMGPNG_02198	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOPMGPNG_02199	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
IOPMGPNG_02200	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IOPMGPNG_02201	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOPMGPNG_02202	1.1e-168	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOPMGPNG_02203	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IOPMGPNG_02204	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IOPMGPNG_02205	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IOPMGPNG_02206	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOPMGPNG_02207	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IOPMGPNG_02208	4.31e-176	yphF	-	-	-	-	-	-	-
IOPMGPNG_02209	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
IOPMGPNG_02210	8.18e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IOPMGPNG_02211	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IOPMGPNG_02212	2.06e-38	ypzH	-	-	-	-	-	-	-
IOPMGPNG_02213	3.58e-206	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
IOPMGPNG_02214	1.3e-132	yphA	-	-	-	-	-	-	-
IOPMGPNG_02215	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
IOPMGPNG_02216	6.61e-235	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOPMGPNG_02217	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IOPMGPNG_02218	2.36e-145	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IOPMGPNG_02219	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
IOPMGPNG_02220	1.09e-142	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
IOPMGPNG_02221	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
IOPMGPNG_02222	1.63e-206	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
IOPMGPNG_02223	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IOPMGPNG_02224	9.98e-216	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
IOPMGPNG_02225	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOPMGPNG_02226	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOPMGPNG_02227	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IOPMGPNG_02228	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
IOPMGPNG_02229	5.32e-139	ypbE	-	-	M	-	-	-	Lysin motif
IOPMGPNG_02230	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
IOPMGPNG_02231	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOPMGPNG_02232	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
IOPMGPNG_02233	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
IOPMGPNG_02234	6.2e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOPMGPNG_02235	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOPMGPNG_02236	2.38e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOPMGPNG_02237	5.11e-246	rsiX	-	-	-	-	-	-	-
IOPMGPNG_02238	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_02239	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_02240	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_02241	1.34e-278	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IOPMGPNG_02242	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
IOPMGPNG_02243	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IOPMGPNG_02244	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOPMGPNG_02245	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
IOPMGPNG_02246	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
IOPMGPNG_02247	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOPMGPNG_02248	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
IOPMGPNG_02249	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOPMGPNG_02250	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOPMGPNG_02251	2.51e-120	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
IOPMGPNG_02252	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_02253	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOPMGPNG_02254	4.24e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IOPMGPNG_02255	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IOPMGPNG_02256	1.45e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOPMGPNG_02257	5.98e-72	ypuD	-	-	-	-	-	-	-
IOPMGPNG_02258	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IOPMGPNG_02259	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
IOPMGPNG_02260	5.49e-17	-	-	-	S	-	-	-	SNARE associated Golgi protein
IOPMGPNG_02263	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOPMGPNG_02264	8.93e-192	ypuA	-	-	S	-	-	-	Secreted protein
IOPMGPNG_02265	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOPMGPNG_02266	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
IOPMGPNG_02267	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IOPMGPNG_02268	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IOPMGPNG_02269	1.41e-198	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IOPMGPNG_02270	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IOPMGPNG_02271	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
IOPMGPNG_02272	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
IOPMGPNG_02273	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_02274	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IOPMGPNG_02275	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
IOPMGPNG_02276	3.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IOPMGPNG_02277	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IOPMGPNG_02278	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOPMGPNG_02279	7.9e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
IOPMGPNG_02280	2.25e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
IOPMGPNG_02281	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IOPMGPNG_02282	7.97e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IOPMGPNG_02283	3.08e-43	yqkK	-	-	-	-	-	-	-
IOPMGPNG_02284	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IOPMGPNG_02285	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IOPMGPNG_02286	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
IOPMGPNG_02287	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
IOPMGPNG_02288	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02289	2.93e-280	yqxK	-	-	L	-	-	-	DNA helicase
IOPMGPNG_02290	1.17e-119	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IOPMGPNG_02291	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
IOPMGPNG_02292	8.88e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IOPMGPNG_02293	6.55e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IOPMGPNG_02294	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
IOPMGPNG_02295	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
IOPMGPNG_02296	1.08e-246	yqkA	-	-	K	-	-	-	GrpB protein
IOPMGPNG_02297	2.73e-72	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
IOPMGPNG_02298	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IOPMGPNG_02299	3.23e-66	yqiX	-	-	S	-	-	-	YolD-like protein
IOPMGPNG_02300	7.79e-302	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOPMGPNG_02302	2.45e-286	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
IOPMGPNG_02304	1.06e-92	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOPMGPNG_02305	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IOPMGPNG_02306	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
IOPMGPNG_02307	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_02308	1.56e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOPMGPNG_02309	9.98e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOPMGPNG_02310	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IOPMGPNG_02311	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IOPMGPNG_02312	6.4e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOPMGPNG_02313	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOPMGPNG_02314	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOPMGPNG_02315	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOPMGPNG_02316	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOPMGPNG_02317	1.84e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOPMGPNG_02318	1.77e-32	yqzJ	-	-	-	-	-	-	-
IOPMGPNG_02319	1.03e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOPMGPNG_02320	5.7e-180	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
IOPMGPNG_02321	8.71e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
IOPMGPNG_02322	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOPMGPNG_02323	6.89e-97	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
IOPMGPNG_02325	2.82e-127	yqjB	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02326	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IOPMGPNG_02327	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOPMGPNG_02328	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOPMGPNG_02329	2.89e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOPMGPNG_02330	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
IOPMGPNG_02331	1.21e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOPMGPNG_02332	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_02333	1.06e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
IOPMGPNG_02334	6.52e-289	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOPMGPNG_02335	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOPMGPNG_02336	2.24e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOPMGPNG_02337	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOPMGPNG_02338	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
IOPMGPNG_02339	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOPMGPNG_02340	3.02e-199	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
IOPMGPNG_02341	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
IOPMGPNG_02342	5.23e-45	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
IOPMGPNG_02343	1.52e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IOPMGPNG_02344	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
IOPMGPNG_02345	2.16e-263	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IOPMGPNG_02346	1.65e-266	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
IOPMGPNG_02347	4.86e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
IOPMGPNG_02348	2.32e-280	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IOPMGPNG_02349	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IOPMGPNG_02350	3.83e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
IOPMGPNG_02351	2.26e-37	-	-	-	-	-	-	-	-
IOPMGPNG_02352	5.08e-276	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IOPMGPNG_02354	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IOPMGPNG_02355	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
IOPMGPNG_02356	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IOPMGPNG_02357	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IOPMGPNG_02358	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
IOPMGPNG_02359	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOPMGPNG_02360	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IOPMGPNG_02361	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOPMGPNG_02362	5.04e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOPMGPNG_02363	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOPMGPNG_02364	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOPMGPNG_02365	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02366	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IOPMGPNG_02367	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOPMGPNG_02368	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
IOPMGPNG_02369	8.86e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
IOPMGPNG_02370	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
IOPMGPNG_02371	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
IOPMGPNG_02372	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
IOPMGPNG_02373	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
IOPMGPNG_02374	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
IOPMGPNG_02375	2.36e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
IOPMGPNG_02376	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
IOPMGPNG_02377	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOPMGPNG_02378	1.22e-248	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IOPMGPNG_02379	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IOPMGPNG_02380	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
IOPMGPNG_02381	5.16e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
IOPMGPNG_02382	2.11e-80	yqhP	-	-	-	-	-	-	-
IOPMGPNG_02383	3.33e-208	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IOPMGPNG_02384	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IOPMGPNG_02385	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IOPMGPNG_02386	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
IOPMGPNG_02387	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOPMGPNG_02388	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOPMGPNG_02389	6.4e-260	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
IOPMGPNG_02390	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOPMGPNG_02391	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
IOPMGPNG_02392	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
IOPMGPNG_02393	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
IOPMGPNG_02394	1.28e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
IOPMGPNG_02395	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
IOPMGPNG_02396	8e-156	yqxM	-	-	-	ko:K19433	-	ko00000	-
IOPMGPNG_02397	3.03e-69	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IOPMGPNG_02398	8.16e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
IOPMGPNG_02399	7.97e-59	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
IOPMGPNG_02400	9.65e-59	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IOPMGPNG_02401	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
IOPMGPNG_02402	1.05e-88	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
IOPMGPNG_02403	3.09e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IOPMGPNG_02404	2.14e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
IOPMGPNG_02405	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IOPMGPNG_02407	3.8e-06	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
IOPMGPNG_02408	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
IOPMGPNG_02409	2.86e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOPMGPNG_02410	7.14e-192	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOPMGPNG_02412	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IOPMGPNG_02413	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
IOPMGPNG_02414	3.2e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IOPMGPNG_02415	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
IOPMGPNG_02416	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
IOPMGPNG_02417	2.69e-256	yqgU	-	-	-	-	-	-	-
IOPMGPNG_02418	3.04e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
IOPMGPNG_02419	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IOPMGPNG_02420	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IOPMGPNG_02421	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
IOPMGPNG_02422	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IOPMGPNG_02423	3.38e-14	yqgO	-	-	-	-	-	-	-
IOPMGPNG_02424	3.8e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOPMGPNG_02425	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IOPMGPNG_02426	1.49e-252	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
IOPMGPNG_02428	3.42e-68	yqzD	-	-	-	-	-	-	-
IOPMGPNG_02429	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
IOPMGPNG_02430	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOPMGPNG_02431	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOPMGPNG_02432	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IOPMGPNG_02433	1.43e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IOPMGPNG_02434	7.59e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IOPMGPNG_02435	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IOPMGPNG_02436	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
IOPMGPNG_02437	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IOPMGPNG_02438	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
IOPMGPNG_02439	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IOPMGPNG_02440	3.32e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
IOPMGPNG_02441	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOPMGPNG_02442	2.04e-81	yqfX	-	-	S	-	-	-	membrane
IOPMGPNG_02443	3.36e-141	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
IOPMGPNG_02444	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
IOPMGPNG_02445	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOPMGPNG_02446	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
IOPMGPNG_02447	2.1e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOPMGPNG_02448	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOPMGPNG_02449	8.34e-48	yqfQ	-	-	S	-	-	-	YqfQ-like protein
IOPMGPNG_02450	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOPMGPNG_02451	4.4e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOPMGPNG_02452	2.81e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IOPMGPNG_02453	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IOPMGPNG_02454	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOPMGPNG_02455	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOPMGPNG_02456	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
IOPMGPNG_02457	1.06e-189	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOPMGPNG_02458	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
IOPMGPNG_02459	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IOPMGPNG_02460	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IOPMGPNG_02461	7.48e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IOPMGPNG_02462	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
IOPMGPNG_02463	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOPMGPNG_02464	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IOPMGPNG_02465	5.77e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IOPMGPNG_02466	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOPMGPNG_02467	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
IOPMGPNG_02469	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
IOPMGPNG_02470	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
IOPMGPNG_02471	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
IOPMGPNG_02472	4e-66	yqfB	-	-	-	-	-	-	-
IOPMGPNG_02473	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
IOPMGPNG_02474	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
IOPMGPNG_02475	9.15e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IOPMGPNG_02476	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IOPMGPNG_02477	5.71e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IOPMGPNG_02478	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
IOPMGPNG_02479	1.38e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOPMGPNG_02480	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
IOPMGPNG_02481	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOPMGPNG_02482	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IOPMGPNG_02483	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOPMGPNG_02484	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOPMGPNG_02485	1.18e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IOPMGPNG_02486	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOPMGPNG_02487	4.25e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
IOPMGPNG_02488	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
IOPMGPNG_02489	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IOPMGPNG_02490	8.09e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IOPMGPNG_02491	4.06e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IOPMGPNG_02492	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IOPMGPNG_02493	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IOPMGPNG_02494	2.14e-134	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IOPMGPNG_02495	1.74e-185	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOPMGPNG_02496	1.39e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
IOPMGPNG_02497	1.39e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOPMGPNG_02498	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IOPMGPNG_02499	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOPMGPNG_02500	3.65e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
IOPMGPNG_02501	4.88e-200	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOPMGPNG_02502	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IOPMGPNG_02503	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IOPMGPNG_02505	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOPMGPNG_02506	2.2e-172	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IOPMGPNG_02507	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
IOPMGPNG_02508	1.5e-85	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
IOPMGPNG_02509	1.27e-88	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
IOPMGPNG_02510	9.38e-171	-	-	-	-	-	-	-	-
IOPMGPNG_02511	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IOPMGPNG_02512	2.33e-71	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_02513	4.77e-46	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_02514	9.01e-285	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
IOPMGPNG_02515	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
IOPMGPNG_02516	6.36e-81	-	-	-	K	-	-	-	BetI-type transcriptional repressor, C-terminal
IOPMGPNG_02517	4.12e-178	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IOPMGPNG_02518	2.62e-219	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IOPMGPNG_02519	5.27e-143	-	-	-	C	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_02520	7.69e-160	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_02521	7.1e-252	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
IOPMGPNG_02522	1.29e-196	-	-	-	E	-	-	-	TAP-like protein
IOPMGPNG_02523	2.84e-123	-	-	-	K	ko:K16137	-	ko00000,ko03000	QacR-like protein, C-terminal region
IOPMGPNG_02524	2.49e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOPMGPNG_02525	4.18e-283	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOPMGPNG_02526	1.71e-33	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IOPMGPNG_02527	2.69e-50	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOPMGPNG_02528	5.12e-71	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
IOPMGPNG_02529	1.52e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
IOPMGPNG_02531	8.57e-207	-	-	-	S	-	-	-	Bacterial EndoU nuclease
IOPMGPNG_02532	5.2e-25	-	-	-	-	-	-	-	-
IOPMGPNG_02533	2.99e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOPMGPNG_02534	3.43e-33	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IOPMGPNG_02535	1.43e-104	yqaS	-	-	L	-	-	-	DNA packaging
IOPMGPNG_02537	7.29e-36	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
IOPMGPNG_02538	4.7e-98	yqaQ	-	-	L	-	-	-	Transposase
IOPMGPNG_02540	1.44e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IOPMGPNG_02543	1.12e-205	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
IOPMGPNG_02544	4.53e-118	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IOPMGPNG_02545	6.37e-125	yqaC	-	-	F	-	-	-	adenylate kinase activity
IOPMGPNG_02547	3.32e-124	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IOPMGPNG_02548	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOPMGPNG_02549	1.94e-145	tetR3	-	-	K	ko:K18476	-	ko00000,ko00002,ko03000	Transcriptional regulator
IOPMGPNG_02550	2.72e-275	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	Multidrug transporter MatE
IOPMGPNG_02551	1.2e-205	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
IOPMGPNG_02552	3.74e-152	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOPMGPNG_02553	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
IOPMGPNG_02554	3.58e-264	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
IOPMGPNG_02555	2.67e-125	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
IOPMGPNG_02556	1.96e-108	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
IOPMGPNG_02557	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02558	1.82e-137	yrkC	-	-	G	-	-	-	Cupin domain
IOPMGPNG_02560	8.38e-193	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IOPMGPNG_02561	1.31e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_02562	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
IOPMGPNG_02563	1.52e-299	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOPMGPNG_02564	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
IOPMGPNG_02565	2.84e-215	yrdR	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_02566	2.83e-203	-	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02567	1.43e-252	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
IOPMGPNG_02568	8.83e-214	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
IOPMGPNG_02569	3.91e-80	yodA	-	-	S	-	-	-	tautomerase
IOPMGPNG_02570	2.84e-207	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IOPMGPNG_02571	4.99e-292	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOPMGPNG_02572	1.62e-65	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
IOPMGPNG_02573	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
IOPMGPNG_02574	4.13e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
IOPMGPNG_02575	1.47e-59	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IOPMGPNG_02576	5.38e-290	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOPMGPNG_02578	2.11e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
IOPMGPNG_02579	6.04e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
IOPMGPNG_02580	1.93e-116	yrdA	-	-	S	-	-	-	DinB family
IOPMGPNG_02581	4.06e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
IOPMGPNG_02582	2.55e-247	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IOPMGPNG_02583	2.4e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOPMGPNG_02584	2.29e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
IOPMGPNG_02586	7.31e-167	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IOPMGPNG_02587	3.99e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_02588	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
IOPMGPNG_02589	1.52e-285	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IOPMGPNG_02590	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02591	1.71e-262	yraM	-	-	S	-	-	-	PrpF protein
IOPMGPNG_02592	9.5e-201	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IOPMGPNG_02593	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_02594	2.33e-194	-	-	-	S	-	-	-	Alpha beta hydrolase
IOPMGPNG_02595	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
IOPMGPNG_02596	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
IOPMGPNG_02598	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
IOPMGPNG_02599	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
IOPMGPNG_02600	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
IOPMGPNG_02601	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOPMGPNG_02602	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
IOPMGPNG_02603	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
IOPMGPNG_02604	3.7e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IOPMGPNG_02605	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
IOPMGPNG_02606	2.25e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IOPMGPNG_02607	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOPMGPNG_02608	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IOPMGPNG_02609	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IOPMGPNG_02610	4.41e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
IOPMGPNG_02611	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IOPMGPNG_02612	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
IOPMGPNG_02613	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_02614	4.63e-136	yrhP	-	-	E	-	-	-	LysE type translocator
IOPMGPNG_02615	1.98e-192	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
IOPMGPNG_02616	5.77e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_02617	1.23e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IOPMGPNG_02618	2.01e-26	oatA	-	-	I	-	-	-	Acyltransferase family
IOPMGPNG_02619	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
IOPMGPNG_02620	7.65e-62	yrhK	-	-	S	-	-	-	YrhK-like protein
IOPMGPNG_02621	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IOPMGPNG_02622	1.12e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IOPMGPNG_02623	2.13e-124	yrhH	-	-	Q	-	-	-	methyltransferase
IOPMGPNG_02624	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
IOPMGPNG_02626	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
IOPMGPNG_02628	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IOPMGPNG_02629	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IOPMGPNG_02630	1.22e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IOPMGPNG_02631	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
IOPMGPNG_02632	4.24e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IOPMGPNG_02633	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
IOPMGPNG_02634	1.14e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOPMGPNG_02635	9.86e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
IOPMGPNG_02636	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
IOPMGPNG_02637	4.72e-101	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
IOPMGPNG_02638	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
IOPMGPNG_02639	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOPMGPNG_02640	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IOPMGPNG_02641	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
IOPMGPNG_02642	6.57e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IOPMGPNG_02643	1.7e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
IOPMGPNG_02644	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOPMGPNG_02645	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IOPMGPNG_02646	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOPMGPNG_02647	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IOPMGPNG_02648	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOPMGPNG_02649	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
IOPMGPNG_02650	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOPMGPNG_02651	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOPMGPNG_02652	2.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOPMGPNG_02653	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOPMGPNG_02654	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
IOPMGPNG_02655	8.4e-42	yrzR	-	-	-	-	-	-	-
IOPMGPNG_02656	3.39e-106	yrrD	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02657	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOPMGPNG_02658	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
IOPMGPNG_02659	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOPMGPNG_02660	1.87e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IOPMGPNG_02661	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_02662	2.44e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IOPMGPNG_02663	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IOPMGPNG_02664	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOPMGPNG_02665	1.27e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IOPMGPNG_02667	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
IOPMGPNG_02668	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOPMGPNG_02669	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOPMGPNG_02670	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOPMGPNG_02671	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IOPMGPNG_02672	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IOPMGPNG_02673	6.51e-114	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IOPMGPNG_02674	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IOPMGPNG_02675	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
IOPMGPNG_02676	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOPMGPNG_02677	2.12e-145	yrbG	-	-	S	-	-	-	membrane
IOPMGPNG_02678	1.25e-97	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
IOPMGPNG_02679	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
IOPMGPNG_02680	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOPMGPNG_02681	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOPMGPNG_02682	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
IOPMGPNG_02683	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOPMGPNG_02684	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOPMGPNG_02685	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
IOPMGPNG_02686	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
IOPMGPNG_02687	3.61e-115	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IOPMGPNG_02688	4.42e-109	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IOPMGPNG_02689	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
IOPMGPNG_02691	7.31e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
IOPMGPNG_02692	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IOPMGPNG_02693	4.78e-162	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IOPMGPNG_02694	7.28e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOPMGPNG_02695	2.43e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
IOPMGPNG_02696	6.53e-272	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOPMGPNG_02697	5.07e-202	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
IOPMGPNG_02698	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IOPMGPNG_02699	8.24e-291	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IOPMGPNG_02700	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IOPMGPNG_02701	4.1e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IOPMGPNG_02702	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IOPMGPNG_02703	7.94e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOPMGPNG_02704	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
IOPMGPNG_02705	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IOPMGPNG_02706	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
IOPMGPNG_02707	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IOPMGPNG_02708	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
IOPMGPNG_02709	5.24e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IOPMGPNG_02710	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IOPMGPNG_02711	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOPMGPNG_02712	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
IOPMGPNG_02713	1.91e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IOPMGPNG_02714	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
IOPMGPNG_02715	1.97e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IOPMGPNG_02716	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
IOPMGPNG_02717	3.08e-206	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
IOPMGPNG_02718	5.2e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IOPMGPNG_02719	2.22e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IOPMGPNG_02720	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOPMGPNG_02721	1.53e-35	-	-	-	-	-	-	-	-
IOPMGPNG_02722	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IOPMGPNG_02723	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
IOPMGPNG_02724	5.85e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IOPMGPNG_02725	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
IOPMGPNG_02726	6.12e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IOPMGPNG_02727	1.08e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IOPMGPNG_02728	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
IOPMGPNG_02729	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IOPMGPNG_02730	6.77e-116	ysxD	-	-	-	-	-	-	-
IOPMGPNG_02731	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IOPMGPNG_02732	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IOPMGPNG_02733	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
IOPMGPNG_02734	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOPMGPNG_02735	8.87e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOPMGPNG_02736	1.58e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
IOPMGPNG_02737	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOPMGPNG_02738	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOPMGPNG_02739	6.1e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOPMGPNG_02740	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOPMGPNG_02741	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOPMGPNG_02742	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IOPMGPNG_02743	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IOPMGPNG_02745	3.07e-103	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
IOPMGPNG_02746	7.92e-182	ysnF	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_02748	2.34e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IOPMGPNG_02749	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOPMGPNG_02750	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOPMGPNG_02751	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
IOPMGPNG_02752	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IOPMGPNG_02753	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_02754	2.64e-206	-	-	-	L	-	-	-	Recombinase
IOPMGPNG_02755	3.39e-59	-	-	-	S	-	-	-	YolD-like protein
IOPMGPNG_02756	6.31e-79	-	-	-	-	-	-	-	-
IOPMGPNG_02758	1.26e-141	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IOPMGPNG_02759	1.58e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
IOPMGPNG_02760	1.95e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IOPMGPNG_02761	2.03e-17	xkdX	-	-	-	-	-	-	-
IOPMGPNG_02763	3.44e-49	-	-	-	-	-	-	-	-
IOPMGPNG_02764	8.61e-79	-	-	-	-	-	-	-	-
IOPMGPNG_02765	7.44e-135	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
IOPMGPNG_02766	2.25e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IOPMGPNG_02768	2.6e-111	-	-	-	-	-	-	-	-
IOPMGPNG_02769	2.64e-40	-	-	-	-	-	-	-	-
IOPMGPNG_02770	3.83e-48	-	-	-	M	-	-	-	LysM domain
IOPMGPNG_02771	1.02e-171	-	-	-	N	-	-	-	phage tail tape measure protein
IOPMGPNG_02772	3.04e-21	-	-	-	-	-	-	-	-
IOPMGPNG_02773	8.46e-46	-	-	-	-	-	-	-	-
IOPMGPNG_02774	2.43e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
IOPMGPNG_02775	7.25e-41	-	-	-	-	-	-	-	-
IOPMGPNG_02777	1.41e-60	-	-	-	-	-	-	-	-
IOPMGPNG_02779	9.21e-37	-	-	-	S	-	-	-	Phage Mu protein F like protein
IOPMGPNG_02781	5.04e-141	-	-	-	S	-	-	-	Phage capsid family
IOPMGPNG_02782	1.56e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
IOPMGPNG_02784	1.29e-198	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IOPMGPNG_02785	6.28e-234	-	-	-	S	-	-	-	Terminase-like family
IOPMGPNG_02786	4.78e-111	yqaS	-	-	L	-	-	-	DNA packaging
IOPMGPNG_02789	5.2e-19	-	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02791	2.62e-91	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IOPMGPNG_02795	8.96e-98	-	-	-	-	-	-	-	-
IOPMGPNG_02797	6.2e-35	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IOPMGPNG_02799	1.57e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IOPMGPNG_02802	6.12e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
IOPMGPNG_02803	1.37e-45	yqaL	-	-	L	-	-	-	DnaD domain protein
IOPMGPNG_02804	3.08e-149	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
IOPMGPNG_02805	1.55e-192	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
IOPMGPNG_02810	2.69e-88	-	-	-	-	-	-	-	-
IOPMGPNG_02811	3.68e-56	-	-	-	S	-	-	-	DNA binding
IOPMGPNG_02813	1.49e-20	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOPMGPNG_02814	1.79e-30	-	-	-	K	ko:K07467	-	ko00000	sequence-specific DNA binding
IOPMGPNG_02816	2.71e-20	-	-	-	-	-	-	-	-
IOPMGPNG_02817	3.35e-63	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IOPMGPNG_02818	6.14e-25	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_02819	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
IOPMGPNG_02820	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IOPMGPNG_02821	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IOPMGPNG_02822	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
IOPMGPNG_02823	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IOPMGPNG_02824	3.96e-275	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IOPMGPNG_02825	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOPMGPNG_02826	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IOPMGPNG_02827	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IOPMGPNG_02829	8.65e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
IOPMGPNG_02830	1.28e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
IOPMGPNG_02831	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
IOPMGPNG_02832	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_02833	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOPMGPNG_02834	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
IOPMGPNG_02835	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOPMGPNG_02836	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
IOPMGPNG_02837	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
IOPMGPNG_02838	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOPMGPNG_02839	2.76e-218	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOPMGPNG_02840	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOPMGPNG_02841	2.57e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOPMGPNG_02842	3.13e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOPMGPNG_02843	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
IOPMGPNG_02844	7.2e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
IOPMGPNG_02845	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
IOPMGPNG_02846	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
IOPMGPNG_02847	1.26e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
IOPMGPNG_02849	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
IOPMGPNG_02850	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
IOPMGPNG_02851	7.39e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
IOPMGPNG_02852	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IOPMGPNG_02853	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IOPMGPNG_02854	6.43e-283	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IOPMGPNG_02855	1.74e-186	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IOPMGPNG_02856	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IOPMGPNG_02857	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
IOPMGPNG_02858	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IOPMGPNG_02859	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IOPMGPNG_02860	4.17e-260	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
IOPMGPNG_02861	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
IOPMGPNG_02862	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
IOPMGPNG_02863	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOPMGPNG_02864	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IOPMGPNG_02865	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOPMGPNG_02867	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOPMGPNG_02868	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOPMGPNG_02869	3.39e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IOPMGPNG_02870	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_02871	1.2e-190	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IOPMGPNG_02872	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOPMGPNG_02873	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
IOPMGPNG_02874	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
IOPMGPNG_02875	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IOPMGPNG_02876	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
IOPMGPNG_02877	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOPMGPNG_02878	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IOPMGPNG_02879	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOPMGPNG_02880	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02881	1.12e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
IOPMGPNG_02882	4.54e-205	ytbE	-	-	S	-	-	-	reductase
IOPMGPNG_02883	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOPMGPNG_02884	4.83e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOPMGPNG_02885	3.88e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOPMGPNG_02886	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOPMGPNG_02887	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
IOPMGPNG_02888	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_02889	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
IOPMGPNG_02890	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
IOPMGPNG_02891	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IOPMGPNG_02892	1.56e-93	ytwI	-	-	S	-	-	-	membrane
IOPMGPNG_02893	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
IOPMGPNG_02894	4.68e-82	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
IOPMGPNG_02895	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IOPMGPNG_02896	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOPMGPNG_02897	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IOPMGPNG_02898	8.83e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOPMGPNG_02899	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IOPMGPNG_02900	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IOPMGPNG_02901	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
IOPMGPNG_02902	5.12e-112	ytrI	-	-	-	-	-	-	-
IOPMGPNG_02903	1.15e-39	-	-	-	-	-	-	-	-
IOPMGPNG_02904	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
IOPMGPNG_02905	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
IOPMGPNG_02906	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IOPMGPNG_02907	6.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOPMGPNG_02908	2.51e-298	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IOPMGPNG_02909	2.7e-163	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
IOPMGPNG_02910	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOPMGPNG_02911	2.07e-60	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
IOPMGPNG_02912	2.31e-232	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOPMGPNG_02913	5.43e-182	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IOPMGPNG_02914	2.75e-154	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOPMGPNG_02915	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOPMGPNG_02916	1.34e-192	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOPMGPNG_02917	5.27e-194	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IOPMGPNG_02918	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IOPMGPNG_02919	1.67e-221	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
IOPMGPNG_02920	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IOPMGPNG_02921	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_02923	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IOPMGPNG_02924	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOPMGPNG_02925	2.33e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IOPMGPNG_02926	2.71e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOPMGPNG_02927	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IOPMGPNG_02928	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOPMGPNG_02929	2.24e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
IOPMGPNG_02930	5.63e-147	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
IOPMGPNG_02931	4.08e-112	yteJ	-	-	S	-	-	-	RDD family
IOPMGPNG_02932	3.96e-229	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
IOPMGPNG_02933	2.92e-190	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOPMGPNG_02934	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
IOPMGPNG_02935	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOPMGPNG_02936	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IOPMGPNG_02937	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOPMGPNG_02938	1.59e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IOPMGPNG_02939	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IOPMGPNG_02940	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOPMGPNG_02941	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IOPMGPNG_02942	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02943	3.24e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IOPMGPNG_02944	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
IOPMGPNG_02945	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOPMGPNG_02947	2.63e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOPMGPNG_02948	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOPMGPNG_02949	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IOPMGPNG_02950	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
IOPMGPNG_02951	8.99e-291	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
IOPMGPNG_02952	3.23e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IOPMGPNG_02953	1.96e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IOPMGPNG_02954	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IOPMGPNG_02955	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IOPMGPNG_02956	2.23e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
IOPMGPNG_02957	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
IOPMGPNG_02958	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOPMGPNG_02959	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IOPMGPNG_02960	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IOPMGPNG_02961	5.1e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOPMGPNG_02962	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
IOPMGPNG_02963	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
IOPMGPNG_02964	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IOPMGPNG_02965	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IOPMGPNG_02966	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
IOPMGPNG_02967	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IOPMGPNG_02968	3.07e-193	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IOPMGPNG_02969	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOPMGPNG_02970	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
IOPMGPNG_02971	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
IOPMGPNG_02972	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IOPMGPNG_02973	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IOPMGPNG_02974	4.92e-212	ytlQ	-	-	-	-	-	-	-
IOPMGPNG_02975	4.29e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IOPMGPNG_02976	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IOPMGPNG_02977	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
IOPMGPNG_02978	1.65e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IOPMGPNG_02979	2.76e-252	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IOPMGPNG_02980	5.66e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOPMGPNG_02981	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
IOPMGPNG_02982	2.49e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IOPMGPNG_02983	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOPMGPNG_02984	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
IOPMGPNG_02985	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IOPMGPNG_02986	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
IOPMGPNG_02987	2.2e-149	yteU	-	-	S	-	-	-	Integral membrane protein
IOPMGPNG_02988	4.18e-315	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IOPMGPNG_02989	1.94e-93	yteS	-	-	G	-	-	-	transport
IOPMGPNG_02990	1.42e-144	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IOPMGPNG_02991	9.69e-100	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IOPMGPNG_02992	1.31e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IOPMGPNG_02993	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_02994	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IOPMGPNG_02995	7.21e-185	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IOPMGPNG_02996	1.28e-177	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
IOPMGPNG_02997	8.47e-284	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOPMGPNG_02998	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IOPMGPNG_02999	1.62e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IOPMGPNG_03000	3.67e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOPMGPNG_03001	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IOPMGPNG_03002	2.73e-180	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IOPMGPNG_03003	3.24e-219	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
IOPMGPNG_03004	2.64e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_03005	2.37e-308	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IOPMGPNG_03006	3.34e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOPMGPNG_03007	6.02e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IOPMGPNG_03008	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IOPMGPNG_03009	4.98e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
IOPMGPNG_03010	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IOPMGPNG_03011	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
IOPMGPNG_03012	5.43e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IOPMGPNG_03013	6.01e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
IOPMGPNG_03014	7.6e-76	yttA	-	-	S	-	-	-	Pfam Transposase IS66
IOPMGPNG_03015	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
IOPMGPNG_03016	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03017	4.53e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
IOPMGPNG_03018	7.76e-168	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_03019	9.81e-297	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IOPMGPNG_03020	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03021	4.53e-190	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IOPMGPNG_03022	3.35e-222	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IOPMGPNG_03023	1.03e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03024	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
IOPMGPNG_03026	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
IOPMGPNG_03027	1.59e-242	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
IOPMGPNG_03028	2.26e-135	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IOPMGPNG_03029	1.61e-274	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
IOPMGPNG_03030	5.49e-191	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
IOPMGPNG_03031	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IOPMGPNG_03032	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_03033	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IOPMGPNG_03034	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOPMGPNG_03035	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IOPMGPNG_03036	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
IOPMGPNG_03037	3.86e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IOPMGPNG_03038	3.1e-239	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IOPMGPNG_03039	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOPMGPNG_03040	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOPMGPNG_03041	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IOPMGPNG_03042	3.2e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
IOPMGPNG_03043	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IOPMGPNG_03045	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
IOPMGPNG_03046	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOPMGPNG_03047	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOPMGPNG_03048	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IOPMGPNG_03049	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IOPMGPNG_03050	4.97e-239	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IOPMGPNG_03051	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
IOPMGPNG_03052	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IOPMGPNG_03053	6.39e-297	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOPMGPNG_03054	1.5e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOPMGPNG_03055	1.13e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IOPMGPNG_03056	7.07e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOPMGPNG_03057	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IOPMGPNG_03058	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IOPMGPNG_03059	9.85e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IOPMGPNG_03060	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IOPMGPNG_03061	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IOPMGPNG_03062	3.53e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IOPMGPNG_03063	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IOPMGPNG_03064	3.37e-309	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOPMGPNG_03065	2.59e-229	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
IOPMGPNG_03066	3.4e-296	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
IOPMGPNG_03068	6.94e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
IOPMGPNG_03069	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
IOPMGPNG_03070	5.46e-262	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
IOPMGPNG_03071	8.04e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
IOPMGPNG_03072	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOPMGPNG_03073	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOPMGPNG_03074	1.84e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
IOPMGPNG_03075	1.15e-262	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOPMGPNG_03076	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOPMGPNG_03098	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IOPMGPNG_03099	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IOPMGPNG_03100	3.31e-120	-	-	-	M	-	-	-	FR47-like protein
IOPMGPNG_03101	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
IOPMGPNG_03102	3.12e-105	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
IOPMGPNG_03103	1.13e-108	yuaE	-	-	S	-	-	-	DinB superfamily
IOPMGPNG_03104	1.17e-136	yuaD	-	-	-	-	-	-	-
IOPMGPNG_03105	2.02e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IOPMGPNG_03106	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOPMGPNG_03107	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
IOPMGPNG_03108	5.83e-118	yuaB	-	-	-	-	-	-	-
IOPMGPNG_03109	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IOPMGPNG_03110	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
IOPMGPNG_03111	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
IOPMGPNG_03112	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOPMGPNG_03113	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
IOPMGPNG_03114	9.32e-112	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
IOPMGPNG_03116	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOPMGPNG_03117	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
IOPMGPNG_03118	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IOPMGPNG_03119	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
IOPMGPNG_03120	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IOPMGPNG_03121	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IOPMGPNG_03122	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOPMGPNG_03123	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
IOPMGPNG_03125	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_03126	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_03127	6.52e-295	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_03128	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_03129	3.56e-180	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IOPMGPNG_03130	5e-48	-	-	-	-	-	-	-	-
IOPMGPNG_03131	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
IOPMGPNG_03132	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOPMGPNG_03133	2.52e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IOPMGPNG_03134	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
IOPMGPNG_03135	6.2e-48	-	-	-	-	-	-	-	-
IOPMGPNG_03136	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
IOPMGPNG_03137	2.92e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
IOPMGPNG_03138	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
IOPMGPNG_03140	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IOPMGPNG_03141	2.64e-289	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
IOPMGPNG_03142	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
IOPMGPNG_03143	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IOPMGPNG_03144	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IOPMGPNG_03145	3.14e-254	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
IOPMGPNG_03146	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03147	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
IOPMGPNG_03148	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
IOPMGPNG_03149	4.53e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IOPMGPNG_03150	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_03151	4.84e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
IOPMGPNG_03152	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
IOPMGPNG_03154	1.08e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
IOPMGPNG_03155	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
IOPMGPNG_03156	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03157	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
IOPMGPNG_03158	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IOPMGPNG_03159	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IOPMGPNG_03160	9.13e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IOPMGPNG_03161	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03162	6.39e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOPMGPNG_03163	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOPMGPNG_03164	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
IOPMGPNG_03165	1.42e-21	-	-	-	-	-	-	-	-
IOPMGPNG_03166	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOPMGPNG_03167	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOPMGPNG_03168	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOPMGPNG_03169	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOPMGPNG_03170	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOPMGPNG_03171	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOPMGPNG_03172	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
IOPMGPNG_03173	1.11e-82	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
IOPMGPNG_03174	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_03175	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_03177	5.75e-182	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
IOPMGPNG_03178	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
IOPMGPNG_03179	1.23e-08	yuzC	-	-	-	-	-	-	-
IOPMGPNG_03180	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
IOPMGPNG_03181	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOPMGPNG_03182	2.69e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
IOPMGPNG_03183	2.19e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IOPMGPNG_03184	1.34e-51	yueH	-	-	S	-	-	-	YueH-like protein
IOPMGPNG_03185	1.23e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
IOPMGPNG_03186	4.52e-243	yueF	-	-	S	-	-	-	transporter activity
IOPMGPNG_03187	1.82e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
IOPMGPNG_03188	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IOPMGPNG_03189	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IOPMGPNG_03190	1.01e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_03191	7.25e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
IOPMGPNG_03192	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
IOPMGPNG_03193	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOPMGPNG_03194	4.28e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IOPMGPNG_03195	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
IOPMGPNG_03196	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
IOPMGPNG_03197	5.98e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
IOPMGPNG_03198	6.66e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IOPMGPNG_03199	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
IOPMGPNG_03200	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
IOPMGPNG_03201	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_03202	4.47e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
IOPMGPNG_03203	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
IOPMGPNG_03204	7.34e-291	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IOPMGPNG_03205	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_03206	8.58e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
IOPMGPNG_03207	3.92e-156	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
IOPMGPNG_03208	4.81e-124	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
IOPMGPNG_03209	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
IOPMGPNG_03210	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IOPMGPNG_03211	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
IOPMGPNG_03212	3.14e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03213	1.14e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
IOPMGPNG_03214	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOPMGPNG_03215	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
IOPMGPNG_03217	4.51e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOPMGPNG_03218	1.27e-65	-	-	-	-	-	-	-	-
IOPMGPNG_03219	8.7e-145	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
IOPMGPNG_03220	8.04e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_03221	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
IOPMGPNG_03222	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOPMGPNG_03223	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOPMGPNG_03224	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
IOPMGPNG_03225	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IOPMGPNG_03226	1.1e-73	yuzD	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03227	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
IOPMGPNG_03228	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
IOPMGPNG_03229	1.04e-220	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOPMGPNG_03230	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IOPMGPNG_03231	2.37e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IOPMGPNG_03232	1.81e-252	yutH	-	-	S	-	-	-	Spore coat protein
IOPMGPNG_03233	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IOPMGPNG_03234	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOPMGPNG_03235	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
IOPMGPNG_03236	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03237	1.57e-143	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOPMGPNG_03238	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IOPMGPNG_03239	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
IOPMGPNG_03240	2.46e-171	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
IOPMGPNG_03241	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
IOPMGPNG_03242	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IOPMGPNG_03243	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IOPMGPNG_03244	8.59e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
IOPMGPNG_03245	1.07e-79	yunG	-	-	-	-	-	-	-
IOPMGPNG_03246	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IOPMGPNG_03247	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
IOPMGPNG_03248	2.82e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
IOPMGPNG_03249	1.35e-284	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IOPMGPNG_03250	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IOPMGPNG_03251	1.47e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IOPMGPNG_03252	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IOPMGPNG_03253	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IOPMGPNG_03254	2.76e-184	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IOPMGPNG_03255	4.18e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
IOPMGPNG_03256	3.87e-238	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IOPMGPNG_03257	4.72e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IOPMGPNG_03258	7.99e-293	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IOPMGPNG_03259	1.08e-216	bsn	-	-	L	-	-	-	Ribonuclease
IOPMGPNG_03260	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_03261	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IOPMGPNG_03262	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IOPMGPNG_03263	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IOPMGPNG_03264	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IOPMGPNG_03265	6.87e-172	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IOPMGPNG_03266	3.25e-113	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IOPMGPNG_03267	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IOPMGPNG_03268	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
IOPMGPNG_03269	7.22e-262	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
IOPMGPNG_03271	3.35e-56	-	-	-	-	-	-	-	-
IOPMGPNG_03272	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
IOPMGPNG_03273	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
IOPMGPNG_03274	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOPMGPNG_03275	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IOPMGPNG_03276	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IOPMGPNG_03277	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOPMGPNG_03278	1.44e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IOPMGPNG_03279	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
IOPMGPNG_03280	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOPMGPNG_03281	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
IOPMGPNG_03282	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
IOPMGPNG_03283	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
IOPMGPNG_03284	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
IOPMGPNG_03285	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IOPMGPNG_03286	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IOPMGPNG_03287	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IOPMGPNG_03288	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
IOPMGPNG_03289	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
IOPMGPNG_03290	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
IOPMGPNG_03291	3.46e-211	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IOPMGPNG_03292	2.23e-54	-	-	-	-	-	-	-	-
IOPMGPNG_03293	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
IOPMGPNG_03294	6.09e-96	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
IOPMGPNG_03295	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
IOPMGPNG_03296	2.93e-85	yusQ	-	-	S	-	-	-	Tautomerase enzyme
IOPMGPNG_03297	2.87e-137	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_03298	3.43e-203	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IOPMGPNG_03299	3.01e-63	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
IOPMGPNG_03300	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOPMGPNG_03301	1.72e-88	-	-	-	S	-	-	-	YusW-like protein
IOPMGPNG_03302	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
IOPMGPNG_03303	6.65e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_03304	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
IOPMGPNG_03305	7.9e-305	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOPMGPNG_03306	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_03307	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_03308	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03309	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOPMGPNG_03310	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
IOPMGPNG_03311	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IOPMGPNG_03312	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IOPMGPNG_03313	3.48e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
IOPMGPNG_03314	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_03315	9.56e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_03316	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IOPMGPNG_03317	6.28e-176	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IOPMGPNG_03318	2.44e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IOPMGPNG_03319	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
IOPMGPNG_03320	7.59e-287	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_03321	4.56e-130	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
IOPMGPNG_03322	0.0	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IOPMGPNG_03323	3.29e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_03324	5.15e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IOPMGPNG_03325	5.21e-182	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_03326	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
IOPMGPNG_03327	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
IOPMGPNG_03328	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_03329	5.07e-32	-	-	-	-	-	-	-	-
IOPMGPNG_03330	4.06e-127	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
IOPMGPNG_03331	4.92e-26	-	-	-	S	-	-	-	YvrJ protein family
IOPMGPNG_03332	3.22e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IOPMGPNG_03333	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
IOPMGPNG_03334	2.21e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IOPMGPNG_03335	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03336	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
IOPMGPNG_03337	2.4e-190	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IOPMGPNG_03338	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_03339	1.21e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOPMGPNG_03340	7.69e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOPMGPNG_03341	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IOPMGPNG_03342	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
IOPMGPNG_03343	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IOPMGPNG_03344	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
IOPMGPNG_03345	2.44e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
IOPMGPNG_03346	2.46e-174	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
IOPMGPNG_03347	6.08e-154	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
IOPMGPNG_03348	6.19e-201	yvgN	-	-	S	-	-	-	reductase
IOPMGPNG_03349	9.32e-112	yvgO	-	-	-	-	-	-	-
IOPMGPNG_03350	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
IOPMGPNG_03351	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IOPMGPNG_03352	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IOPMGPNG_03353	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IOPMGPNG_03355	3.32e-139	yvgT	-	-	S	-	-	-	membrane
IOPMGPNG_03356	1.15e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
IOPMGPNG_03357	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
IOPMGPNG_03358	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IOPMGPNG_03359	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IOPMGPNG_03360	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
IOPMGPNG_03361	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
IOPMGPNG_03362	2.42e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IOPMGPNG_03363	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOPMGPNG_03364	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IOPMGPNG_03365	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
IOPMGPNG_03366	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
IOPMGPNG_03367	2.35e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOPMGPNG_03368	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_03370	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IOPMGPNG_03371	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOPMGPNG_03372	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
IOPMGPNG_03373	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IOPMGPNG_03374	2.24e-191	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
IOPMGPNG_03375	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
IOPMGPNG_03376	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
IOPMGPNG_03377	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IOPMGPNG_03378	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
IOPMGPNG_03379	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IOPMGPNG_03380	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOPMGPNG_03381	1.32e-217	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOPMGPNG_03382	6.3e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOPMGPNG_03383	1.48e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOPMGPNG_03384	1.9e-121	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IOPMGPNG_03385	9.67e-137	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOPMGPNG_03386	2.04e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOPMGPNG_03387	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IOPMGPNG_03388	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOPMGPNG_03389	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IOPMGPNG_03390	1.88e-126	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IOPMGPNG_03391	8.48e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
IOPMGPNG_03392	9.3e-156	yvbI	-	-	M	-	-	-	Membrane
IOPMGPNG_03393	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IOPMGPNG_03394	2.4e-106	yvbK	-	-	K	-	-	-	acetyltransferase
IOPMGPNG_03395	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOPMGPNG_03396	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
IOPMGPNG_03397	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOPMGPNG_03398	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IOPMGPNG_03399	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOPMGPNG_03400	5.69e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOPMGPNG_03401	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOPMGPNG_03402	1.24e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
IOPMGPNG_03403	6.01e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOPMGPNG_03404	4.02e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03405	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_03406	3.69e-235	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_03407	4.04e-50	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IOPMGPNG_03408	2.68e-252	-	-	-	S	-	-	-	Glycosyl hydrolase
IOPMGPNG_03409	4.84e-171	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOPMGPNG_03410	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IOPMGPNG_03411	2.23e-175	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOPMGPNG_03412	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_03413	5.04e-257	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_03414	1.01e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IOPMGPNG_03415	5.95e-209	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
IOPMGPNG_03416	2.43e-199	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
IOPMGPNG_03417	2.8e-261	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
IOPMGPNG_03418	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
IOPMGPNG_03419	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
IOPMGPNG_03420	1.56e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IOPMGPNG_03421	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IOPMGPNG_03422	1.55e-290	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IOPMGPNG_03423	1.3e-236	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_03424	1.18e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
IOPMGPNG_03425	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IOPMGPNG_03426	9.59e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IOPMGPNG_03427	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
IOPMGPNG_03428	3.44e-237	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
IOPMGPNG_03429	4.31e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IOPMGPNG_03430	1.01e-77	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IOPMGPNG_03431	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOPMGPNG_03432	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOPMGPNG_03433	6.21e-242	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOPMGPNG_03434	9.86e-262	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
IOPMGPNG_03435	1e-247	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IOPMGPNG_03436	3.59e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
IOPMGPNG_03437	1.23e-275	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IOPMGPNG_03438	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IOPMGPNG_03439	2.83e-284	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
IOPMGPNG_03440	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IOPMGPNG_03441	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IOPMGPNG_03442	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IOPMGPNG_03443	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
IOPMGPNG_03444	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IOPMGPNG_03446	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IOPMGPNG_03447	7.42e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
IOPMGPNG_03448	2.5e-162	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IOPMGPNG_03449	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
IOPMGPNG_03450	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
IOPMGPNG_03451	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IOPMGPNG_03452	0.0	ybeC	-	-	E	-	-	-	amino acid
IOPMGPNG_03453	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03454	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IOPMGPNG_03455	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IOPMGPNG_03456	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
IOPMGPNG_03457	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
IOPMGPNG_03458	2.71e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
IOPMGPNG_03460	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOPMGPNG_03461	5.57e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IOPMGPNG_03462	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IOPMGPNG_03463	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
IOPMGPNG_03464	3.68e-198	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IOPMGPNG_03465	3.79e-187	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IOPMGPNG_03466	4.11e-309	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IOPMGPNG_03467	1.99e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IOPMGPNG_03468	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
IOPMGPNG_03469	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03470	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IOPMGPNG_03471	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IOPMGPNG_03472	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IOPMGPNG_03473	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IOPMGPNG_03474	1.15e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOPMGPNG_03475	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IOPMGPNG_03476	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03477	1.32e-249	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IOPMGPNG_03478	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_03479	1.37e-45	-	-	-	-	-	-	-	-
IOPMGPNG_03480	8.35e-185	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
IOPMGPNG_03481	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
IOPMGPNG_03482	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IOPMGPNG_03483	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IOPMGPNG_03484	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IOPMGPNG_03485	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IOPMGPNG_03486	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOPMGPNG_03487	2.18e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
IOPMGPNG_03488	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
IOPMGPNG_03489	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IOPMGPNG_03491	0.0	-	-	-	-	-	-	-	-
IOPMGPNG_03492	6.36e-172	-	-	-	-	-	-	-	-
IOPMGPNG_03493	2.61e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
IOPMGPNG_03494	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOPMGPNG_03495	1.32e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOPMGPNG_03496	1.15e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOPMGPNG_03497	2.87e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IOPMGPNG_03498	3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOPMGPNG_03499	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOPMGPNG_03500	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOPMGPNG_03501	5.03e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
IOPMGPNG_03502	1.1e-153	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
IOPMGPNG_03503	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IOPMGPNG_03504	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IOPMGPNG_03505	3.72e-211	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
IOPMGPNG_03506	2.15e-193	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOPMGPNG_03507	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOPMGPNG_03508	9.39e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOPMGPNG_03509	8.26e-164	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOPMGPNG_03510	1.5e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IOPMGPNG_03511	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
IOPMGPNG_03512	7.14e-105	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_03513	2.45e-288	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IOPMGPNG_03514	2.79e-174	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
IOPMGPNG_03515	1.03e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_03516	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOPMGPNG_03517	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
IOPMGPNG_03518	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IOPMGPNG_03519	1.66e-220	yvlB	-	-	S	-	-	-	Putative adhesin
IOPMGPNG_03520	8.09e-65	yvlA	-	-	-	-	-	-	-
IOPMGPNG_03521	2.73e-46	yvkN	-	-	-	-	-	-	-
IOPMGPNG_03522	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOPMGPNG_03523	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOPMGPNG_03524	1.64e-44	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOPMGPNG_03525	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOPMGPNG_03526	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03527	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
IOPMGPNG_03528	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03529	8.67e-295	yvkA	-	-	P	-	-	-	-transporter
IOPMGPNG_03530	5.25e-279	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOPMGPNG_03531	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
IOPMGPNG_03532	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IOPMGPNG_03533	4.47e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IOPMGPNG_03534	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IOPMGPNG_03536	5.72e-51	-	-	-	E	-	-	-	Amidinotransferase
IOPMGPNG_03539	3.89e-15	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IOPMGPNG_03540	2.6e-37	-	-	-	S	ko:K07025	-	ko00000	hydrolase
IOPMGPNG_03541	1.36e-60	-	-	-	H	-	-	-	HD domain
IOPMGPNG_03542	5.14e-64	-	-	-	-	-	-	-	-
IOPMGPNG_03544	1.2e-29	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOPMGPNG_03545	7.77e-65	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOPMGPNG_03546	2.69e-104	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOPMGPNG_03547	2.74e-66	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IOPMGPNG_03548	2.37e-68	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IOPMGPNG_03549	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IOPMGPNG_03550	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOPMGPNG_03551	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOPMGPNG_03552	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOPMGPNG_03553	9.14e-88	-	-	-	-	-	-	-	-
IOPMGPNG_03554	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
IOPMGPNG_03555	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
IOPMGPNG_03556	8.97e-313	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IOPMGPNG_03557	1.62e-69	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
IOPMGPNG_03558	1.43e-124	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOPMGPNG_03559	5.02e-39	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IOPMGPNG_03560	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IOPMGPNG_03561	1.7e-92	yviE	-	-	-	-	-	-	-
IOPMGPNG_03562	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
IOPMGPNG_03563	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
IOPMGPNG_03564	1.43e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
IOPMGPNG_03565	4.32e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
IOPMGPNG_03566	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
IOPMGPNG_03567	1.53e-160	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
IOPMGPNG_03568	1.04e-60	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
IOPMGPNG_03569	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IOPMGPNG_03570	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03571	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOPMGPNG_03572	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IOPMGPNG_03573	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
IOPMGPNG_03574	1.09e-222	yvhJ	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03575	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IOPMGPNG_03576	3.69e-300	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
IOPMGPNG_03577	4.87e-186	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IOPMGPNG_03578	1.36e-145	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
IOPMGPNG_03579	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
IOPMGPNG_03580	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOPMGPNG_03581	1.34e-277	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
IOPMGPNG_03582	6.88e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOPMGPNG_03583	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOPMGPNG_03584	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IOPMGPNG_03585	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
IOPMGPNG_03586	3.26e-50	-	-	-	-	-	-	-	-
IOPMGPNG_03587	1.13e-218	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IOPMGPNG_03588	2.58e-275	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOPMGPNG_03589	1.78e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOPMGPNG_03590	3.21e-71	-	-	-	-	-	-	-	-
IOPMGPNG_03591	3.03e-248	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOPMGPNG_03592	1.82e-113	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IOPMGPNG_03593	1.86e-47	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOPMGPNG_03594	2.01e-138	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IOPMGPNG_03595	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IOPMGPNG_03596	2.06e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IOPMGPNG_03597	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOPMGPNG_03598	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
IOPMGPNG_03599	3.82e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
IOPMGPNG_03600	1.9e-185	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOPMGPNG_03601	3.8e-273	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOPMGPNG_03602	0.0	-	-	-	-	-	-	-	-
IOPMGPNG_03603	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOPMGPNG_03604	1.92e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IOPMGPNG_03605	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IOPMGPNG_03606	1.38e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IOPMGPNG_03607	1.27e-272	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IOPMGPNG_03608	1.29e-314	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOPMGPNG_03609	2.11e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03610	8.45e-204	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IOPMGPNG_03611	3.89e-305	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOPMGPNG_03612	2.29e-29	ywtC	-	-	-	-	-	-	-
IOPMGPNG_03613	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IOPMGPNG_03614	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
IOPMGPNG_03615	2.08e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
IOPMGPNG_03616	9.35e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IOPMGPNG_03617	1.85e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOPMGPNG_03618	3.79e-83	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOPMGPNG_03619	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IOPMGPNG_03620	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IOPMGPNG_03621	9.04e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
IOPMGPNG_03622	1.97e-119	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
IOPMGPNG_03623	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
IOPMGPNG_03624	2.15e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
IOPMGPNG_03625	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IOPMGPNG_03626	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IOPMGPNG_03627	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
IOPMGPNG_03628	3.25e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOPMGPNG_03629	5.05e-161	ywrJ	-	-	-	-	-	-	-
IOPMGPNG_03630	5.79e-182	cotB	-	-	-	ko:K06325	-	ko00000	-
IOPMGPNG_03631	9.22e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IOPMGPNG_03632	2.17e-16	-	-	-	-	-	-	-	-
IOPMGPNG_03633	4.35e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IOPMGPNG_03634	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
IOPMGPNG_03635	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IOPMGPNG_03636	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IOPMGPNG_03637	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
IOPMGPNG_03638	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
IOPMGPNG_03640	5.23e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
IOPMGPNG_03641	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03642	4.92e-154	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IOPMGPNG_03643	9.7e-128	-	-	-	-	-	-	-	-
IOPMGPNG_03645	2.2e-66	-	-	-	-	-	-	-	-
IOPMGPNG_03646	1.83e-97	-	-	-	-	-	-	-	-
IOPMGPNG_03647	4.06e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IOPMGPNG_03648	1.3e-23	-	-	-	-	-	-	-	-
IOPMGPNG_03649	1.77e-26	-	-	-	-	-	-	-	-
IOPMGPNG_03650	2.12e-264	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IOPMGPNG_03651	4.98e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
IOPMGPNG_03653	1.99e-194	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
IOPMGPNG_03654	9.82e-315	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOPMGPNG_03655	1.75e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
IOPMGPNG_03656	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IOPMGPNG_03657	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IOPMGPNG_03658	3.6e-25	-	-	-	-	-	-	-	-
IOPMGPNG_03659	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
IOPMGPNG_03660	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOPMGPNG_03661	3.72e-202	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IOPMGPNG_03662	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOPMGPNG_03663	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IOPMGPNG_03664	3.04e-87	ywpG	-	-	-	-	-	-	-
IOPMGPNG_03665	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
IOPMGPNG_03666	4.46e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IOPMGPNG_03667	8.41e-189	ywpD	-	-	T	-	-	-	Histidine kinase
IOPMGPNG_03668	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOPMGPNG_03669	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOPMGPNG_03670	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
IOPMGPNG_03671	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IOPMGPNG_03672	8.4e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IOPMGPNG_03673	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
IOPMGPNG_03674	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
IOPMGPNG_03675	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
IOPMGPNG_03676	2.76e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_03677	1.02e-312	ywoF	-	-	P	-	-	-	Right handed beta helix region
IOPMGPNG_03678	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
IOPMGPNG_03679	4.62e-308	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
IOPMGPNG_03680	2.11e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
IOPMGPNG_03681	9.77e-101	-	-	-	-	-	-	-	-
IOPMGPNG_03682	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
IOPMGPNG_03683	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IOPMGPNG_03684	7.03e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
IOPMGPNG_03685	1.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
IOPMGPNG_03686	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IOPMGPNG_03687	1.55e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
IOPMGPNG_03688	9.25e-22	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IOPMGPNG_03689	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
IOPMGPNG_03690	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOPMGPNG_03691	1.97e-183	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
IOPMGPNG_03692	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IOPMGPNG_03693	9.77e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IOPMGPNG_03694	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03695	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IOPMGPNG_03696	3.2e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IOPMGPNG_03697	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IOPMGPNG_03698	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
IOPMGPNG_03699	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
IOPMGPNG_03700	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IOPMGPNG_03701	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IOPMGPNG_03702	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IOPMGPNG_03704	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IOPMGPNG_03705	1.56e-156	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IOPMGPNG_03706	1.69e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
IOPMGPNG_03707	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOPMGPNG_03708	1.33e-171	ywmB	-	-	S	-	-	-	TATA-box binding
IOPMGPNG_03709	4.54e-45	ywzB	-	-	S	-	-	-	membrane
IOPMGPNG_03710	6.12e-115	ywmA	-	-	-	-	-	-	-
IOPMGPNG_03711	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IOPMGPNG_03712	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOPMGPNG_03713	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOPMGPNG_03714	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOPMGPNG_03715	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOPMGPNG_03716	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOPMGPNG_03717	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOPMGPNG_03718	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IOPMGPNG_03719	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
IOPMGPNG_03720	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOPMGPNG_03721	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOPMGPNG_03722	1.01e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IOPMGPNG_03723	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
IOPMGPNG_03724	4.73e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOPMGPNG_03725	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IOPMGPNG_03726	7.37e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOPMGPNG_03727	1.04e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
IOPMGPNG_03728	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
IOPMGPNG_03729	7.97e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IOPMGPNG_03731	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOPMGPNG_03732	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOPMGPNG_03733	1.56e-87	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOPMGPNG_03734	1.72e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IOPMGPNG_03735	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IOPMGPNG_03736	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IOPMGPNG_03737	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IOPMGPNG_03738	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IOPMGPNG_03739	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOPMGPNG_03740	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
IOPMGPNG_03741	1.31e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOPMGPNG_03742	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOPMGPNG_03743	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
IOPMGPNG_03744	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
IOPMGPNG_03745	1.29e-117	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
IOPMGPNG_03746	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOPMGPNG_03747	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOPMGPNG_03748	1.73e-268	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
IOPMGPNG_03749	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
IOPMGPNG_03750	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IOPMGPNG_03751	8.09e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IOPMGPNG_03752	1.32e-57	ywjC	-	-	-	-	-	-	-
IOPMGPNG_03753	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
IOPMGPNG_03754	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IOPMGPNG_03755	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOPMGPNG_03756	2.06e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
IOPMGPNG_03757	5.59e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
IOPMGPNG_03758	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
IOPMGPNG_03759	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOPMGPNG_03760	2.26e-65	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOPMGPNG_03761	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
IOPMGPNG_03762	8.75e-178	ywiC	-	-	S	-	-	-	YwiC-like protein
IOPMGPNG_03763	6.6e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
IOPMGPNG_03764	1.2e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IOPMGPNG_03765	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IOPMGPNG_03766	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_03767	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
IOPMGPNG_03768	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
IOPMGPNG_03770	3.53e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IOPMGPNG_03771	1.98e-296	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IOPMGPNG_03772	3.29e-274	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
IOPMGPNG_03773	3.9e-316	-	-	-	L	-	-	-	Peptidase, M16
IOPMGPNG_03775	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
IOPMGPNG_03776	1.91e-274	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IOPMGPNG_03777	6.61e-107	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IOPMGPNG_03779	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IOPMGPNG_03780	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IOPMGPNG_03781	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IOPMGPNG_03782	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
IOPMGPNG_03783	1.9e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
IOPMGPNG_03784	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
IOPMGPNG_03785	3.56e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03786	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOPMGPNG_03788	2e-302	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IOPMGPNG_03789	3.15e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03790	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
IOPMGPNG_03791	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
IOPMGPNG_03792	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
IOPMGPNG_03793	1.88e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
IOPMGPNG_03794	9.09e-204	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
IOPMGPNG_03795	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IOPMGPNG_03796	9.56e-212	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_03797	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
IOPMGPNG_03798	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
IOPMGPNG_03799	4.1e-177	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_03800	1.28e-296	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IOPMGPNG_03801	5.31e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IOPMGPNG_03802	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IOPMGPNG_03803	3.83e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_03804	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IOPMGPNG_03805	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IOPMGPNG_03806	4.44e-274	ywfA	-	-	EGP	-	-	-	-transporter
IOPMGPNG_03807	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOPMGPNG_03808	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IOPMGPNG_03809	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOPMGPNG_03810	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IOPMGPNG_03811	3.7e-101	-	-	-	-	-	-	-	-
IOPMGPNG_03812	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
IOPMGPNG_03813	2.34e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOPMGPNG_03814	3.7e-233	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOPMGPNG_03815	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOPMGPNG_03816	1.57e-237	spsG	-	-	M	-	-	-	Spore Coat
IOPMGPNG_03817	6.07e-165	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
IOPMGPNG_03818	1.13e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
IOPMGPNG_03819	1.72e-209	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
IOPMGPNG_03820	9.15e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IOPMGPNG_03821	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
IOPMGPNG_03822	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
IOPMGPNG_03823	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IOPMGPNG_03824	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
IOPMGPNG_03825	1.78e-301	ywdJ	-	-	F	-	-	-	Xanthine uracil
IOPMGPNG_03826	9.23e-65	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
IOPMGPNG_03827	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOPMGPNG_03828	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOPMGPNG_03829	1.9e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
IOPMGPNG_03831	8.74e-146	ywdD	-	-	-	-	-	-	-
IOPMGPNG_03832	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
IOPMGPNG_03833	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IOPMGPNG_03834	1.07e-39	ywdA	-	-	-	-	-	-	-
IOPMGPNG_03835	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IOPMGPNG_03836	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_03837	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
IOPMGPNG_03838	1.83e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IOPMGPNG_03840	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOPMGPNG_03841	8.11e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOPMGPNG_03842	9.4e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
IOPMGPNG_03843	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IOPMGPNG_03844	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
IOPMGPNG_03845	2.74e-141	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IOPMGPNG_03846	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOPMGPNG_03847	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IOPMGPNG_03848	5.11e-49	ydaS	-	-	S	-	-	-	membrane
IOPMGPNG_03849	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IOPMGPNG_03850	1.2e-285	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOPMGPNG_03851	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
IOPMGPNG_03852	4.16e-159	ywcC	-	-	K	-	-	-	transcriptional regulator
IOPMGPNG_03854	2.49e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
IOPMGPNG_03855	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOPMGPNG_03856	1.8e-141	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IOPMGPNG_03857	3.13e-285	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
IOPMGPNG_03858	1.7e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IOPMGPNG_03859	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IOPMGPNG_03860	1.74e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOPMGPNG_03861	3.79e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOPMGPNG_03862	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03863	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IOPMGPNG_03864	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
IOPMGPNG_03865	2.49e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
IOPMGPNG_03866	6.33e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
IOPMGPNG_03867	4e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IOPMGPNG_03868	4.01e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
IOPMGPNG_03869	2.61e-163	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
IOPMGPNG_03870	3.16e-313	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOPMGPNG_03871	9.09e-140	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOPMGPNG_03872	4.63e-193	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IOPMGPNG_03873	1.19e-311	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_03874	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IOPMGPNG_03875	4.41e-215	gspA	-	-	M	-	-	-	General stress
IOPMGPNG_03876	1.42e-157	ywaF	-	-	S	-	-	-	Integral membrane protein
IOPMGPNG_03877	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_03878	6.36e-297	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOPMGPNG_03879	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
IOPMGPNG_03880	1.44e-116	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IOPMGPNG_03881	5.58e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
IOPMGPNG_03882	5.61e-165	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
IOPMGPNG_03883	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
IOPMGPNG_03884	4.89e-211	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IOPMGPNG_03885	1.27e-20	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IOPMGPNG_03886	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_03887	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
IOPMGPNG_03888	1.61e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOPMGPNG_03889	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOPMGPNG_03890	1.38e-176	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_03891	4.36e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IOPMGPNG_03892	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOPMGPNG_03893	1.3e-49	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_03894	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOPMGPNG_03895	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
IOPMGPNG_03896	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IOPMGPNG_03897	8.94e-28	yxzF	-	-	-	-	-	-	-
IOPMGPNG_03898	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IOPMGPNG_03899	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IOPMGPNG_03900	4.58e-270	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
IOPMGPNG_03901	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOPMGPNG_03902	1.93e-209	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03903	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IOPMGPNG_03904	2.92e-42	-	-	-	-	-	-	-	-
IOPMGPNG_03905	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
IOPMGPNG_03906	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IOPMGPNG_03907	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IOPMGPNG_03908	9.16e-203	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOPMGPNG_03909	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
IOPMGPNG_03910	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
IOPMGPNG_03911	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
IOPMGPNG_03912	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IOPMGPNG_03913	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
IOPMGPNG_03914	0.0	-	-	-	O	-	-	-	Peptidase family M48
IOPMGPNG_03916	7.49e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
IOPMGPNG_03917	1.4e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IOPMGPNG_03918	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IOPMGPNG_03919	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOPMGPNG_03920	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOPMGPNG_03921	1.17e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IOPMGPNG_03922	1e-249	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IOPMGPNG_03923	1.89e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
IOPMGPNG_03924	1.13e-257	-	-	-	T	-	-	-	Signal transduction histidine kinase
IOPMGPNG_03925	5.21e-146	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
IOPMGPNG_03926	1.06e-296	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IOPMGPNG_03929	2.96e-49	yxjI	-	-	S	-	-	-	LURP-one-related
IOPMGPNG_03930	1.5e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IOPMGPNG_03931	1.09e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IOPMGPNG_03932	5.83e-176	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IOPMGPNG_03933	6.9e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOPMGPNG_03934	1.56e-166	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOPMGPNG_03935	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
IOPMGPNG_03936	1.7e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
IOPMGPNG_03937	2.98e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOPMGPNG_03938	4.2e-133	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
IOPMGPNG_03939	6.3e-61	yxiS	-	-	-	-	-	-	-
IOPMGPNG_03940	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IOPMGPNG_03941	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IOPMGPNG_03942	1.07e-184	bglS	-	-	M	-	-	-	licheninase activity
IOPMGPNG_03943	2.31e-192	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IOPMGPNG_03944	1.25e-141	-	-	-	-	-	-	-	-
IOPMGPNG_03945	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
IOPMGPNG_03946	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IOPMGPNG_03947	2.09e-266	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IOPMGPNG_03950	5.77e-58	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IOPMGPNG_03951	7.86e-113	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
IOPMGPNG_03952	1.09e-169	-	-	-	-	-	-	-	-
IOPMGPNG_03953	5.34e-93	yxiG	-	-	-	-	-	-	-
IOPMGPNG_03954	1.22e-46	-	-	-	-	-	-	-	-
IOPMGPNG_03955	2.07e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_03956	1.36e-160	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOPMGPNG_03957	9.17e-157	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
IOPMGPNG_03958	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
IOPMGPNG_03959	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOPMGPNG_03960	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IOPMGPNG_03961	8.25e-69	-	-	-	-	-	-	-	-
IOPMGPNG_03962	1.08e-63	-	-	-	-	-	-	-	-
IOPMGPNG_03963	0.0	-	-	-	S	-	-	-	nuclease activity
IOPMGPNG_03964	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
IOPMGPNG_03965	5.09e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
IOPMGPNG_03966	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IOPMGPNG_03967	1.66e-101	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IOPMGPNG_03968	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
IOPMGPNG_03969	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IOPMGPNG_03970	3.7e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
IOPMGPNG_03971	1.14e-229	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IOPMGPNG_03972	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOPMGPNG_03973	6.66e-298	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
IOPMGPNG_03974	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOPMGPNG_03975	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOPMGPNG_03976	1.22e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOPMGPNG_03977	3.05e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
IOPMGPNG_03978	5.43e-256	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
IOPMGPNG_03979	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
IOPMGPNG_03980	2.37e-271	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IOPMGPNG_03981	3.94e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03982	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IOPMGPNG_03983	1.01e-184	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IOPMGPNG_03984	2.99e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOPMGPNG_03985	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOPMGPNG_03986	6.41e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IOPMGPNG_03987	3.29e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
IOPMGPNG_03990	7.32e-42	yxeE	-	-	-	-	-	-	-
IOPMGPNG_03991	7.57e-28	yxeD	-	-	-	-	-	-	-
IOPMGPNG_03992	9.65e-91	-	-	-	-	-	-	-	-
IOPMGPNG_03993	2.03e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IOPMGPNG_03994	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IOPMGPNG_03995	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IOPMGPNG_03996	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IOPMGPNG_03997	2.7e-231	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_03998	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_03999	5.71e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IOPMGPNG_04000	1.96e-194	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IOPMGPNG_04001	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IOPMGPNG_04002	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IOPMGPNG_04003	5.7e-296	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
IOPMGPNG_04004	1.23e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IOPMGPNG_04005	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IOPMGPNG_04006	3.52e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IOPMGPNG_04007	1.46e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IOPMGPNG_04008	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOPMGPNG_04009	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IOPMGPNG_04010	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IOPMGPNG_04012	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
IOPMGPNG_04013	1.02e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOPMGPNG_04014	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
IOPMGPNG_04016	1.39e-191	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IOPMGPNG_04017	2.43e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IOPMGPNG_04018	1.39e-312	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IOPMGPNG_04019	2.93e-27	yxaI	-	-	S	-	-	-	membrane protein domain
IOPMGPNG_04020	2.63e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
IOPMGPNG_04021	2.38e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
IOPMGPNG_04022	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
IOPMGPNG_04023	7.25e-284	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IOPMGPNG_04024	8.59e-250	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
IOPMGPNG_04025	1.36e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IOPMGPNG_04026	2.04e-253	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IOPMGPNG_04027	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IOPMGPNG_04028	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
IOPMGPNG_04029	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
IOPMGPNG_04030	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IOPMGPNG_04031	2.92e-132	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IOPMGPNG_04032	5.15e-106	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IOPMGPNG_04033	2.56e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
IOPMGPNG_04034	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IOPMGPNG_04035	4.81e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IOPMGPNG_04036	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOPMGPNG_04037	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
IOPMGPNG_04038	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
IOPMGPNG_04039	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IOPMGPNG_04040	1.23e-162	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
IOPMGPNG_04041	2.4e-23	-	-	-	-	-	-	-	-
IOPMGPNG_04042	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
IOPMGPNG_04043	0.0	-	-	-	L	-	-	-	AAA domain
IOPMGPNG_04044	6.93e-310	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IOPMGPNG_04045	3.64e-56	-	-	-	S	-	-	-	MazG-like family
IOPMGPNG_04046	4.8e-142	-	-	-	S	-	-	-	Caspase domain
IOPMGPNG_04047	1.23e-134	-	-	-	L	-	-	-	reverse transcriptase
IOPMGPNG_04049	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOPMGPNG_04051	3.06e-85	-	-	-	-	-	-	-	-
IOPMGPNG_04052	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOPMGPNG_04054	4.53e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IOPMGPNG_04055	3.25e-256	yycP	-	-	-	-	-	-	-
IOPMGPNG_04056	1.96e-168	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IOPMGPNG_04057	9.06e-112	yycN	-	-	K	-	-	-	Acetyltransferase
IOPMGPNG_04058	4.31e-239	-	-	-	S	-	-	-	aspartate phosphatase
IOPMGPNG_04060	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IOPMGPNG_04061	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IOPMGPNG_04062	2.89e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
IOPMGPNG_04063	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IOPMGPNG_04064	5.27e-214	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IOPMGPNG_04065	2.36e-122	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
IOPMGPNG_04066	1.88e-97	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IOPMGPNG_04067	2.2e-42	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IOPMGPNG_04068	1.05e-275	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOPMGPNG_04069	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IOPMGPNG_04070	2.83e-199	yycI	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_04071	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_04072	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IOPMGPNG_04073	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOPMGPNG_04078	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOPMGPNG_04079	1.34e-98	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOPMGPNG_04080	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IOPMGPNG_04081	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IOPMGPNG_04083	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
IOPMGPNG_04084	2.83e-281	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
IOPMGPNG_04085	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOPMGPNG_04086	5.52e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IOPMGPNG_04087	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IOPMGPNG_04088	1.5e-204	yybS	-	-	S	-	-	-	membrane
IOPMGPNG_04090	6.83e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IOPMGPNG_04091	6.43e-88	yybR	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_04092	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
IOPMGPNG_04093	3.19e-90	-	-	-	-	-	-	-	-
IOPMGPNG_04095	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_04096	5.1e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IOPMGPNG_04097	1.14e-180	-	-	-	-	-	-	-	-
IOPMGPNG_04098	1.01e-86	-	-	-	S	-	-	-	SnoaL-like domain
IOPMGPNG_04099	4.65e-161	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
IOPMGPNG_04100	2.49e-276	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_04101	6.48e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_04102	1.87e-102	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_04103	3.21e-93	yybC	-	-	-	-	-	-	-
IOPMGPNG_04104	5.94e-162	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IOPMGPNG_04105	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
IOPMGPNG_04106	6.19e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IOPMGPNG_04107	1.23e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
IOPMGPNG_04108	2.33e-120	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
IOPMGPNG_04109	5.21e-86	-	-	-	S	-	-	-	YjbR
IOPMGPNG_04110	1.37e-133	yyaP	-	-	H	-	-	-	RibD C-terminal domain
IOPMGPNG_04111	0.0	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
IOPMGPNG_04112	2.43e-57	yyaL	-	-	O	ko:K06888	-	ko00000	Highly conserved protein containing a thioredoxin domain
IOPMGPNG_04113	5.45e-88	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IOPMGPNG_04114	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
IOPMGPNG_04115	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IOPMGPNG_04116	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IOPMGPNG_04117	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
IOPMGPNG_04118	7.68e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IOPMGPNG_04119	2.82e-87	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOPMGPNG_04120	5.63e-226	ccpB	-	-	K	-	-	-	Transcriptional regulator
IOPMGPNG_04121	7.76e-183	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IOPMGPNG_04122	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOPMGPNG_04123	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOPMGPNG_04124	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IOPMGPNG_04125	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOPMGPNG_04126	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOPMGPNG_04127	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
IOPMGPNG_04128	2.17e-226	yyaD	-	-	S	-	-	-	Membrane
IOPMGPNG_04129	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
IOPMGPNG_04130	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IOPMGPNG_04131	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
IOPMGPNG_04132	1.08e-96	-	-	-	S	-	-	-	Bacterial PH domain
IOPMGPNG_04133	2.12e-191	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IOPMGPNG_04134	5.86e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IOPMGPNG_04135	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOPMGPNG_04136	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOPMGPNG_04137	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
IOPMGPNG_04138	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOPMGPNG_04139	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme