ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KPHECLMH_00001 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KPHECLMH_00002 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
KPHECLMH_00003 2.24e-246 - - - EGP - - - Major Facilitator
KPHECLMH_00004 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
KPHECLMH_00005 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
KPHECLMH_00006 2.38e-156 - - - - - - - -
KPHECLMH_00007 2.16e-303 - - - NU - - - Mycoplasma protein of unknown function, DUF285
KPHECLMH_00008 1.47e-83 - - - - - - - -
KPHECLMH_00009 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_00010 8.64e-183 ynjC - - S - - - Cell surface protein
KPHECLMH_00011 4.78e-43 ynjC - - S - - - Cell surface protein
KPHECLMH_00012 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
KPHECLMH_00013 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
KPHECLMH_00014 1.09e-224 - - - C - - - Alcohol dehydrogenase GroES-like domain
KPHECLMH_00015 7.02e-136 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_00016 7.3e-246 - - - S - - - Cell surface protein
KPHECLMH_00017 2.69e-99 - - - - - - - -
KPHECLMH_00018 0.0 - - - - - - - -
KPHECLMH_00019 2.06e-287 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KPHECLMH_00020 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
KPHECLMH_00021 2.81e-181 - - - K - - - Helix-turn-helix domain
KPHECLMH_00022 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KPHECLMH_00023 1.36e-84 - - - S - - - Cupredoxin-like domain
KPHECLMH_00024 1.49e-58 - - - S - - - Cupredoxin-like domain
KPHECLMH_00025 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KPHECLMH_00026 2.77e-271 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
KPHECLMH_00027 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
KPHECLMH_00028 1.67e-86 lysM - - M - - - LysM domain
KPHECLMH_00029 0.0 - - - E - - - Amino Acid
KPHECLMH_00030 4.1e-184 - - - K - - - Helix-turn-helix XRE-family like proteins
KPHECLMH_00031 1.97e-92 - - - - - - - -
KPHECLMH_00033 4.9e-208 yhxD - - IQ - - - KR domain
KPHECLMH_00034 3.1e-288 amd - - E - - - Peptidase family M20/M25/M40
KPHECLMH_00035 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00036 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00037 1.1e-275 - - - - - - - -
KPHECLMH_00038 2.4e-151 - - - GM - - - NAD(P)H-binding
KPHECLMH_00039 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
KPHECLMH_00040 3.55e-79 - - - I - - - sulfurtransferase activity
KPHECLMH_00041 6.7e-102 yphH - - S - - - Cupin domain
KPHECLMH_00042 1.37e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KPHECLMH_00043 2.15e-151 - - - GM - - - NAD(P)H-binding
KPHECLMH_00044 2.57e-179 - - - C - - - C4-dicarboxylate transmembrane transporter activity
KPHECLMH_00045 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
KPHECLMH_00046 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
KPHECLMH_00047 1.49e-41 - - - L ko:K07497 - ko00000 hmm pf00665
KPHECLMH_00048 6.57e-274 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KPHECLMH_00049 2.02e-39 - - - - - - - -
KPHECLMH_00050 1.48e-71 - - - - - - - -
KPHECLMH_00051 1.14e-193 - - - O - - - Band 7 protein
KPHECLMH_00052 0.0 - - - EGP - - - Major Facilitator
KPHECLMH_00053 1.22e-120 - - - K - - - transcriptional regulator
KPHECLMH_00054 1.54e-246 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPHECLMH_00055 4.94e-114 ykhA - - I - - - Thioesterase superfamily
KPHECLMH_00056 5.3e-207 - - - K - - - LysR substrate binding domain
KPHECLMH_00057 7.34e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KPHECLMH_00058 2.9e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
KPHECLMH_00059 5.4e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KPHECLMH_00060 1.96e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
KPHECLMH_00061 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPHECLMH_00062 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
KPHECLMH_00063 8.45e-92 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
KPHECLMH_00064 4.31e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPHECLMH_00065 1.08e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPHECLMH_00066 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KPHECLMH_00067 2.85e-214 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
KPHECLMH_00068 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPHECLMH_00069 1.62e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPHECLMH_00070 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KPHECLMH_00071 8.02e-230 yneE - - K - - - Transcriptional regulator
KPHECLMH_00072 1.13e-184 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_00073 3.34e-54 - - - S - - - Protein of unknown function (DUF1648)
KPHECLMH_00074 2.16e-162 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KPHECLMH_00075 3.38e-274 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
KPHECLMH_00076 2.87e-186 - - - E - - - glutamate:sodium symporter activity
KPHECLMH_00077 7.13e-75 - - - E - - - glutamate:sodium symporter activity
KPHECLMH_00078 1.87e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
KPHECLMH_00079 3.38e-225 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
KPHECLMH_00080 2.64e-47 entB - - Q - - - Isochorismatase family
KPHECLMH_00081 2.79e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KPHECLMH_00082 3.77e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KPHECLMH_00083 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
KPHECLMH_00084 5.93e-166 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KPHECLMH_00085 5.77e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPHECLMH_00086 9.44e-134 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
KPHECLMH_00087 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
KPHECLMH_00089 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
KPHECLMH_00090 5.4e-175 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KPHECLMH_00091 1.43e-178 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
KPHECLMH_00092 1.05e-48 - - - GK - - - ROK family
KPHECLMH_00093 1.07e-16 - - - GK - - - ROK family
KPHECLMH_00094 1.73e-136 gph - - G ko:K03292 - ko00000 transporter
KPHECLMH_00095 2.83e-275 - - - G - - - Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KPHECLMH_00096 9.28e-72 - - - K - - - transcriptional regulator (AraC family)
KPHECLMH_00097 9.3e-154 - - - C - - - nadph quinone reductase
KPHECLMH_00098 1.32e-77 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_00099 4.49e-112 - - - - - - - -
KPHECLMH_00100 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KPHECLMH_00101 3.2e-70 - - - - - - - -
KPHECLMH_00102 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KPHECLMH_00103 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KPHECLMH_00104 6.42e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPHECLMH_00105 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KPHECLMH_00106 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KPHECLMH_00107 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPHECLMH_00108 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KPHECLMH_00109 3.14e-297 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPHECLMH_00110 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KPHECLMH_00111 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPHECLMH_00112 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPHECLMH_00113 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KPHECLMH_00114 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPHECLMH_00115 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
KPHECLMH_00116 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
KPHECLMH_00117 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KPHECLMH_00118 1.07e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KPHECLMH_00119 3.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KPHECLMH_00120 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPHECLMH_00121 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KPHECLMH_00122 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KPHECLMH_00123 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPHECLMH_00124 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPHECLMH_00125 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPHECLMH_00126 2.5e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPHECLMH_00127 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KPHECLMH_00128 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KPHECLMH_00129 8.28e-73 - - - - - - - -
KPHECLMH_00130 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_00131 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KPHECLMH_00132 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_00133 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00134 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KPHECLMH_00135 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KPHECLMH_00136 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KPHECLMH_00137 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KPHECLMH_00138 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPHECLMH_00139 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPHECLMH_00140 2.79e-193 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPHECLMH_00141 2.82e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPHECLMH_00142 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
KPHECLMH_00143 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPHECLMH_00144 5.79e-247 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KPHECLMH_00145 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KPHECLMH_00146 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
KPHECLMH_00147 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KPHECLMH_00148 8.15e-125 - - - K - - - Transcriptional regulator
KPHECLMH_00149 9.81e-27 - - - - - - - -
KPHECLMH_00150 8.02e-110 - - - S - - - Pfam:DUF3816
KPHECLMH_00151 3.47e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPHECLMH_00152 1.27e-143 - - - - - - - -
KPHECLMH_00153 1.08e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KPHECLMH_00154 1.57e-184 - - - S - - - Peptidase_C39 like family
KPHECLMH_00155 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
KPHECLMH_00156 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KPHECLMH_00157 3.82e-188 - - - KT - - - helix_turn_helix, mercury resistance
KPHECLMH_00158 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KPHECLMH_00159 5.35e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
KPHECLMH_00160 4.88e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KPHECLMH_00161 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00162 2.27e-116 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
KPHECLMH_00163 8.13e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
KPHECLMH_00164 1.45e-126 ywjB - - H - - - RibD C-terminal domain
KPHECLMH_00165 8.02e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPHECLMH_00166 7.4e-154 - - - S - - - Membrane
KPHECLMH_00167 3.49e-198 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
KPHECLMH_00168 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
KPHECLMH_00169 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
KPHECLMH_00170 3.85e-158 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KPHECLMH_00171 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
KPHECLMH_00172 2.33e-103 - - - S - - - Domain of unknown function (DUF4811)
KPHECLMH_00173 7.96e-127 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KPHECLMH_00174 4.38e-222 - - - S - - - Conserved hypothetical protein 698
KPHECLMH_00175 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
KPHECLMH_00176 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
KPHECLMH_00177 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KPHECLMH_00179 9.92e-88 - - - M - - - LysM domain
KPHECLMH_00180 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
KPHECLMH_00181 5.77e-213 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00182 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPHECLMH_00183 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_00184 4.72e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KPHECLMH_00185 1.37e-99 yphH - - S - - - Cupin domain
KPHECLMH_00186 5.19e-103 - - - K - - - transcriptional regulator, MerR family
KPHECLMH_00187 1.46e-299 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KPHECLMH_00188 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KPHECLMH_00189 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00191 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPHECLMH_00192 1.84e-140 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KPHECLMH_00193 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KPHECLMH_00195 4.86e-111 - - - - - - - -
KPHECLMH_00196 1.04e-110 yvbK - - K - - - GNAT family
KPHECLMH_00197 9.76e-50 - - - - - - - -
KPHECLMH_00198 2.81e-64 - - - - - - - -
KPHECLMH_00199 1.02e-13 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
KPHECLMH_00200 4.14e-110 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
KPHECLMH_00201 6.09e-83 - - - S - - - Domain of unknown function (DUF4440)
KPHECLMH_00202 1.51e-200 - - - K - - - LysR substrate binding domain
KPHECLMH_00203 1.52e-135 - - - GM - - - NAD(P)H-binding
KPHECLMH_00204 1.66e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KPHECLMH_00205 2.9e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KPHECLMH_00206 1.28e-45 - - - - - - - -
KPHECLMH_00207 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
KPHECLMH_00208 8.17e-122 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
KPHECLMH_00209 1.02e-161 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KPHECLMH_00210 2.31e-79 - - - - - - - -
KPHECLMH_00211 5.29e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
KPHECLMH_00212 2.33e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KPHECLMH_00213 1.07e-131 - - - M - - - Protein of unknown function (DUF3737)
KPHECLMH_00214 2.46e-247 - - - C - - - Aldo/keto reductase family
KPHECLMH_00216 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00217 1.85e-49 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00218 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00219 6.27e-316 - - - EGP - - - Major Facilitator
KPHECLMH_00223 2.06e-314 yhgE - - V ko:K01421 - ko00000 domain protein
KPHECLMH_00224 3.01e-124 - - - K - - - Transcriptional regulator (TetR family)
KPHECLMH_00225 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_00226 4.19e-197 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KPHECLMH_00227 1.34e-132 yokL3 - - J - - - Acetyltransferase (GNAT) domain
KPHECLMH_00228 1.24e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KPHECLMH_00229 1.07e-123 - - - M - - - Phosphotransferase enzyme family
KPHECLMH_00230 1.78e-29 - - - M - - - Phosphotransferase enzyme family
KPHECLMH_00231 2.62e-281 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KPHECLMH_00232 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
KPHECLMH_00233 1.52e-129 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KPHECLMH_00234 3.4e-16 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KPHECLMH_00235 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KPHECLMH_00236 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
KPHECLMH_00237 9.48e-265 - - - EGP - - - Major facilitator Superfamily
KPHECLMH_00238 7.97e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
KPHECLMH_00239 2.83e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
KPHECLMH_00240 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
KPHECLMH_00241 2.85e-206 - - - I - - - alpha/beta hydrolase fold
KPHECLMH_00242 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
KPHECLMH_00243 0.0 - - - - - - - -
KPHECLMH_00244 2e-52 - - - S - - - Cytochrome B5
KPHECLMH_00245 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPHECLMH_00246 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
KPHECLMH_00247 1.63e-162 - - - T - - - Putative diguanylate phosphodiesterase
KPHECLMH_00248 7.74e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPHECLMH_00249 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KPHECLMH_00250 1.56e-108 - - - - - - - -
KPHECLMH_00251 6.98e-95 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KPHECLMH_00252 3.08e-241 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPHECLMH_00253 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPHECLMH_00254 7.16e-30 - - - - - - - -
KPHECLMH_00255 2.99e-133 - - - - - - - -
KPHECLMH_00256 3.46e-210 - - - K - - - LysR substrate binding domain
KPHECLMH_00257 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
KPHECLMH_00258 1.09e-65 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
KPHECLMH_00259 2.19e-270 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
KPHECLMH_00260 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KPHECLMH_00261 1.61e-183 - - - S - - - zinc-ribbon domain
KPHECLMH_00263 4.29e-50 - - - - - - - -
KPHECLMH_00264 1.48e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
KPHECLMH_00265 2.35e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KPHECLMH_00266 0.0 - - - I - - - acetylesterase activity
KPHECLMH_00267 1.54e-78 - - - M - - - Collagen binding domain
KPHECLMH_00268 2.58e-274 - - - T - - - diguanylate cyclase
KPHECLMH_00269 9.17e-45 - - - - - - - -
KPHECLMH_00270 2.29e-48 - - - - - - - -
KPHECLMH_00271 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
KPHECLMH_00272 2.47e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
KPHECLMH_00273 2e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_00275 2.68e-32 - - - - - - - -
KPHECLMH_00276 8.05e-178 - - - F - - - NUDIX domain
KPHECLMH_00277 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
KPHECLMH_00278 1.08e-63 - - - - - - - -
KPHECLMH_00279 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
KPHECLMH_00281 1.26e-218 - - - EG - - - EamA-like transporter family
KPHECLMH_00282 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KPHECLMH_00283 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KPHECLMH_00284 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
KPHECLMH_00285 0.0 yclK - - T - - - Histidine kinase
KPHECLMH_00286 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
KPHECLMH_00287 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
KPHECLMH_00288 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KPHECLMH_00289 2.1e-33 - - - - - - - -
KPHECLMH_00290 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00291 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KPHECLMH_00292 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
KPHECLMH_00293 4.63e-24 - - - - - - - -
KPHECLMH_00294 2.16e-26 - - - - - - - -
KPHECLMH_00295 9.35e-24 - - - - - - - -
KPHECLMH_00296 9.35e-24 - - - - - - - -
KPHECLMH_00297 1.07e-26 - - - - - - - -
KPHECLMH_00298 1.56e-22 - - - - - - - -
KPHECLMH_00299 3.26e-24 - - - - - - - -
KPHECLMH_00300 6.58e-24 - - - - - - - -
KPHECLMH_00301 0.0 inlJ - - M - - - MucBP domain
KPHECLMH_00302 0.0 - - - D - - - nuclear chromosome segregation
KPHECLMH_00303 1.27e-109 - - - K - - - MarR family
KPHECLMH_00304 1.09e-56 - - - - - - - -
KPHECLMH_00305 1.28e-51 - - - - - - - -
KPHECLMH_00307 8.08e-40 - - - - - - - -
KPHECLMH_00309 5.54e-199 int3 - - L - - - Belongs to the 'phage' integrase family
KPHECLMH_00310 2.18e-20 int3 - - L - - - Belongs to the 'phage' integrase family
KPHECLMH_00311 2.61e-16 - - - - - - - -
KPHECLMH_00314 1.65e-101 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
KPHECLMH_00316 6.54e-92 - - - - - - - -
KPHECLMH_00319 1.27e-16 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
KPHECLMH_00322 2.08e-22 - - - K ko:K22299 - ko00000,ko03000 sequence-specific DNA binding
KPHECLMH_00323 6.94e-05 - - - K - - - PFAM helix-turn-helix domain protein
KPHECLMH_00324 1.72e-172 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
KPHECLMH_00325 6.41e-207 - - - L - - - DnaD domain protein
KPHECLMH_00326 2.67e-66 - - - - - - - -
KPHECLMH_00327 1.29e-80 - - - - - - - -
KPHECLMH_00328 5.7e-87 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KPHECLMH_00329 5.18e-08 - - - - - - - -
KPHECLMH_00330 3.86e-107 - - - S - - - Phage transcriptional regulator, ArpU family
KPHECLMH_00335 1.55e-24 - - - - - - - -
KPHECLMH_00336 1.99e-23 - - - - - - - -
KPHECLMH_00337 6.24e-72 - - - L ko:K07474 - ko00000 Terminase small subunit
KPHECLMH_00338 1.72e-235 - - - S - - - Phage terminase, large subunit, PBSX family
KPHECLMH_00339 7.55e-137 - - - S - - - Phage portal protein, SPP1 Gp6-like
KPHECLMH_00340 4.97e-55 - - - S - - - Phage minor capsid protein 2
KPHECLMH_00343 2.84e-134 - - - - - - - -
KPHECLMH_00344 4.22e-06 - - - - - - - -
KPHECLMH_00349 3.24e-58 - - - N - - - domain, Protein
KPHECLMH_00352 2.04e-179 - - - L - - - Phage tail tape measure protein TP901
KPHECLMH_00354 2.84e-123 - - - S - - - Prophage endopeptidase tail
KPHECLMH_00357 4.07e-11 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KPHECLMH_00358 0.0 - - - S - - - Calcineurin-like phosphoesterase
KPHECLMH_00361 6.54e-234 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KPHECLMH_00362 4.55e-64 - - - - - - - -
KPHECLMH_00363 2.46e-58 - - - S - - - Bacteriophage holin
KPHECLMH_00365 4.03e-168 icaB - - G - - - Polysaccharide deacetylase
KPHECLMH_00366 5.63e-89 yxeA - - S - - - Protein of unknown function (DUF1093)
KPHECLMH_00367 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00368 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
KPHECLMH_00369 5.37e-182 - - - - - - - -
KPHECLMH_00370 2.31e-95 - - - M - - - LysM domain protein
KPHECLMH_00371 1.41e-86 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
KPHECLMH_00372 2.59e-228 - - - - - - - -
KPHECLMH_00373 4.65e-168 - - - - - - - -
KPHECLMH_00374 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
KPHECLMH_00375 2.03e-75 - - - - - - - -
KPHECLMH_00376 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPHECLMH_00377 1.26e-100 - - - S ko:K02348 - ko00000 GNAT family
KPHECLMH_00378 1.24e-99 - - - K - - - Transcriptional regulator
KPHECLMH_00379 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KPHECLMH_00380 2.18e-53 - - - - - - - -
KPHECLMH_00381 3.07e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00382 1.31e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_00383 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_00384 5.94e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPHECLMH_00385 3.68e-125 - - - K - - - Cupin domain
KPHECLMH_00386 8.08e-110 - - - S - - - ASCH
KPHECLMH_00387 1.88e-111 - - - K - - - GNAT family
KPHECLMH_00388 1.02e-115 - - - K - - - acetyltransferase
KPHECLMH_00389 2.06e-30 - - - - - - - -
KPHECLMH_00390 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KPHECLMH_00391 7.53e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00392 1.08e-243 - - - - - - - -
KPHECLMH_00393 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
KPHECLMH_00394 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
KPHECLMH_00396 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
KPHECLMH_00397 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
KPHECLMH_00398 7.28e-42 - - - - - - - -
KPHECLMH_00399 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KPHECLMH_00400 6.4e-54 - - - - - - - -
KPHECLMH_00401 6.26e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KPHECLMH_00402 3.52e-226 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPHECLMH_00403 4.03e-81 - - - S - - - CHY zinc finger
KPHECLMH_00404 1.05e-282 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KPHECLMH_00405 3.41e-190 - - - - - - - -
KPHECLMH_00406 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00407 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
KPHECLMH_00408 1.37e-55 - - - - - - - -
KPHECLMH_00409 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KPHECLMH_00410 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00411 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
KPHECLMH_00412 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_00413 3.44e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
KPHECLMH_00414 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KPHECLMH_00415 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
KPHECLMH_00416 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
KPHECLMH_00417 2.26e-304 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
KPHECLMH_00418 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPHECLMH_00419 1.66e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPHECLMH_00420 9.7e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KPHECLMH_00421 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPHECLMH_00422 1.63e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPHECLMH_00423 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPHECLMH_00424 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPHECLMH_00425 2.97e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KPHECLMH_00426 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPHECLMH_00427 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KPHECLMH_00428 9.06e-279 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KPHECLMH_00429 4.17e-163 - - - E - - - Methionine synthase
KPHECLMH_00430 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
KPHECLMH_00431 2.62e-121 - - - - - - - -
KPHECLMH_00432 8.43e-198 - - - T - - - EAL domain
KPHECLMH_00433 2.24e-206 - - - GM - - - NmrA-like family
KPHECLMH_00434 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
KPHECLMH_00435 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KPHECLMH_00436 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
KPHECLMH_00437 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPHECLMH_00438 4.08e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KPHECLMH_00439 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPHECLMH_00440 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KPHECLMH_00441 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KPHECLMH_00442 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPHECLMH_00443 1.27e-160 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KPHECLMH_00444 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPHECLMH_00445 1.12e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
KPHECLMH_00446 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KPHECLMH_00447 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KPHECLMH_00448 8.98e-30 - - - K - - - Acetyltransferase (GNAT) family
KPHECLMH_00449 1.29e-148 - - - GM - - - NAD(P)H-binding
KPHECLMH_00450 5.73e-208 mleR - - K - - - LysR family
KPHECLMH_00451 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
KPHECLMH_00452 3.59e-26 - - - - - - - -
KPHECLMH_00453 1.21e-183 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPHECLMH_00454 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KPHECLMH_00455 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
KPHECLMH_00456 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPHECLMH_00457 4.71e-74 - - - S - - - SdpI/YhfL protein family
KPHECLMH_00458 1.27e-219 - - - C - - - Zinc-binding dehydrogenase
KPHECLMH_00459 4.71e-81 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_00460 2.03e-271 yttB - - EGP - - - Major Facilitator
KPHECLMH_00461 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
KPHECLMH_00462 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
KPHECLMH_00463 0.0 yhdP - - S - - - Transporter associated domain
KPHECLMH_00464 2.97e-76 - - - - - - - -
KPHECLMH_00465 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KPHECLMH_00466 1.55e-79 - - - - - - - -
KPHECLMH_00467 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
KPHECLMH_00468 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
KPHECLMH_00469 5.66e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KPHECLMH_00470 1.74e-178 - - - - - - - -
KPHECLMH_00471 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPHECLMH_00472 3.53e-169 - - - K - - - Transcriptional regulator
KPHECLMH_00473 4.74e-208 - - - S - - - Putative esterase
KPHECLMH_00474 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KPHECLMH_00475 5.31e-285 - - - M - - - Glycosyl transferases group 1
KPHECLMH_00476 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
KPHECLMH_00477 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
KPHECLMH_00478 2.12e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
KPHECLMH_00479 1.09e-55 - - - S - - - zinc-ribbon domain
KPHECLMH_00480 3.77e-24 - - - - - - - -
KPHECLMH_00481 5.88e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KPHECLMH_00482 1.02e-102 uspA3 - - T - - - universal stress protein
KPHECLMH_00483 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KPHECLMH_00484 1.49e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KPHECLMH_00485 4.28e-184 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
KPHECLMH_00486 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
KPHECLMH_00487 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KPHECLMH_00488 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
KPHECLMH_00489 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KPHECLMH_00490 4.15e-78 - - - - - - - -
KPHECLMH_00491 1.65e-97 - - - - - - - -
KPHECLMH_00492 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
KPHECLMH_00493 1.57e-71 - - - - - - - -
KPHECLMH_00494 6.46e-61 - - - - - - - -
KPHECLMH_00495 6.69e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KPHECLMH_00496 9.89e-74 ytpP - - CO - - - Thioredoxin
KPHECLMH_00497 4.85e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
KPHECLMH_00498 9.66e-88 - - - - - - - -
KPHECLMH_00499 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_00500 4.83e-64 - - - - - - - -
KPHECLMH_00501 1.75e-75 - - - - - - - -
KPHECLMH_00503 1.86e-210 - - - - - - - -
KPHECLMH_00504 1.4e-95 - - - K - - - Transcriptional regulator
KPHECLMH_00505 0.0 pepF2 - - E - - - Oligopeptidase F
KPHECLMH_00506 2.67e-222 ybcH - - D ko:K06889 - ko00000 Alpha beta
KPHECLMH_00507 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KPHECLMH_00508 4.6e-169 - - - S - - - Putative threonine/serine exporter
KPHECLMH_00509 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
KPHECLMH_00510 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KPHECLMH_00511 4.15e-153 - - - I - - - phosphatase
KPHECLMH_00512 3.88e-198 - - - I - - - alpha/beta hydrolase fold
KPHECLMH_00513 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KPHECLMH_00514 1.7e-118 - - - K - - - Transcriptional regulator
KPHECLMH_00515 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KPHECLMH_00516 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
KPHECLMH_00517 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KPHECLMH_00518 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
KPHECLMH_00519 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPHECLMH_00527 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KPHECLMH_00528 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KPHECLMH_00529 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_00530 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPHECLMH_00531 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPHECLMH_00532 1.81e-150 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
KPHECLMH_00533 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPHECLMH_00534 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KPHECLMH_00535 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPHECLMH_00536 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KPHECLMH_00537 3.05e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPHECLMH_00538 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KPHECLMH_00539 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPHECLMH_00540 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPHECLMH_00541 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPHECLMH_00542 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPHECLMH_00543 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPHECLMH_00544 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPHECLMH_00545 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KPHECLMH_00546 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPHECLMH_00547 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPHECLMH_00548 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPHECLMH_00549 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPHECLMH_00550 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPHECLMH_00551 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPHECLMH_00552 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPHECLMH_00553 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPHECLMH_00554 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KPHECLMH_00555 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KPHECLMH_00556 8.45e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPHECLMH_00557 3.72e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPHECLMH_00558 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPHECLMH_00559 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPHECLMH_00560 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPHECLMH_00561 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPHECLMH_00562 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KPHECLMH_00563 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KPHECLMH_00564 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
KPHECLMH_00565 5.37e-112 - - - S - - - NusG domain II
KPHECLMH_00566 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KPHECLMH_00567 3.19e-194 - - - S - - - FMN_bind
KPHECLMH_00568 6.21e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPHECLMH_00569 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPHECLMH_00570 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPHECLMH_00571 2.39e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPHECLMH_00572 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPHECLMH_00573 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPHECLMH_00574 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KPHECLMH_00575 8.17e-208 yitS - - S - - - Uncharacterised protein, DegV family COG1307
KPHECLMH_00576 2.46e-235 - - - S - - - Membrane
KPHECLMH_00577 7.79e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
KPHECLMH_00578 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPHECLMH_00579 2.25e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPHECLMH_00580 2.71e-234 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
KPHECLMH_00581 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPHECLMH_00582 2.37e-280 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KPHECLMH_00583 4.33e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
KPHECLMH_00584 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
KPHECLMH_00585 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
KPHECLMH_00586 1.28e-253 - - - K - - - Helix-turn-helix domain
KPHECLMH_00587 1.57e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KPHECLMH_00588 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KPHECLMH_00589 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
KPHECLMH_00590 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KPHECLMH_00591 1.18e-66 - - - - - - - -
KPHECLMH_00592 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KPHECLMH_00593 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KPHECLMH_00594 8.69e-230 citR - - K - - - sugar-binding domain protein
KPHECLMH_00595 7.83e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
KPHECLMH_00596 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KPHECLMH_00597 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
KPHECLMH_00598 1.06e-206 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
KPHECLMH_00599 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
KPHECLMH_00600 1.98e-232 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
KPHECLMH_00602 9.54e-65 - - - K - - - sequence-specific DNA binding
KPHECLMH_00604 9.65e-172 yicL - - EG - - - EamA-like transporter family
KPHECLMH_00605 1.44e-164 - - - E - - - lipolytic protein G-D-S-L family
KPHECLMH_00606 2.27e-189 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
KPHECLMH_00607 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
KPHECLMH_00608 1.85e-51 - - - K - - - HxlR-like helix-turn-helix
KPHECLMH_00609 4.54e-208 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KPHECLMH_00610 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
KPHECLMH_00611 4.02e-116 - - - - - - - -
KPHECLMH_00612 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KPHECLMH_00613 7.39e-121 - - - K - - - Transcriptional regulator, MarR family
KPHECLMH_00614 2.47e-126 ccpB - - K - - - lacI family
KPHECLMH_00615 1.53e-46 ccpB - - K - - - lacI family
KPHECLMH_00616 2.21e-154 yceE - - S - - - haloacid dehalogenase-like hydrolase
KPHECLMH_00617 3.29e-153 ydgI3 - - C - - - Nitroreductase family
KPHECLMH_00618 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KPHECLMH_00619 4.21e-150 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KPHECLMH_00620 1.01e-198 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPHECLMH_00621 5.98e-217 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_00622 0.0 - - - - - - - -
KPHECLMH_00623 4.71e-81 - - - - - - - -
KPHECLMH_00624 9.55e-243 - - - S - - - Cell surface protein
KPHECLMH_00625 7.34e-137 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_00626 5.06e-82 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KPHECLMH_00627 3.84e-42 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
KPHECLMH_00628 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_00629 5.21e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
KPHECLMH_00630 7.65e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
KPHECLMH_00631 1.61e-195 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
KPHECLMH_00632 8.54e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
KPHECLMH_00634 1.35e-42 - - - - - - - -
KPHECLMH_00635 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
KPHECLMH_00636 2.88e-106 gtcA3 - - S - - - GtrA-like protein
KPHECLMH_00637 3.35e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
KPHECLMH_00638 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KPHECLMH_00639 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
KPHECLMH_00640 7.03e-62 - - - - - - - -
KPHECLMH_00641 1.81e-150 - - - S - - - SNARE associated Golgi protein
KPHECLMH_00642 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
KPHECLMH_00643 7.89e-124 - - - P - - - Cadmium resistance transporter
KPHECLMH_00644 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00645 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
KPHECLMH_00646 2.86e-52 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KPHECLMH_00649 1.38e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KPHECLMH_00650 4.58e-228 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KPHECLMH_00651 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KPHECLMH_00652 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KPHECLMH_00653 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KPHECLMH_00654 3.06e-205 mleR2 - - K - - - LysR family transcriptional regulator
KPHECLMH_00655 6.5e-215 mleR - - K - - - LysR family
KPHECLMH_00656 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
KPHECLMH_00657 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
KPHECLMH_00658 0.0 - - - E ko:K03294 - ko00000 Amino Acid
KPHECLMH_00659 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
KPHECLMH_00660 2.66e-137 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_00661 8.87e-173 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KPHECLMH_00663 2.38e-176 repA - - S - - - Replication initiator protein A
KPHECLMH_00664 4.25e-26 - - - Q - - - Methyltransferase
KPHECLMH_00665 5.94e-69 - - - Q - - - Methyltransferase
KPHECLMH_00666 1.77e-145 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
KPHECLMH_00667 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
KPHECLMH_00668 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
KPHECLMH_00669 3.59e-204 - - - S - - - Alpha beta hydrolase
KPHECLMH_00670 1.39e-143 - - - GM - - - NmrA-like family
KPHECLMH_00671 1.74e-101 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
KPHECLMH_00672 5.72e-207 - - - K - - - Transcriptional regulator
KPHECLMH_00673 3.78e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
KPHECLMH_00675 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KPHECLMH_00676 1.51e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
KPHECLMH_00677 5.11e-266 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPHECLMH_00678 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KPHECLMH_00679 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_00681 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KPHECLMH_00682 1.93e-94 - - - K - - - MarR family
KPHECLMH_00683 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
KPHECLMH_00684 0.000123 - - - S - - - Protein of unknown function (DUF2992)
KPHECLMH_00685 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00686 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPHECLMH_00687 1.01e-251 - - - - - - - -
KPHECLMH_00688 1.5e-255 - - - - - - - -
KPHECLMH_00689 1.42e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00690 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KPHECLMH_00691 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPHECLMH_00692 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KPHECLMH_00693 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KPHECLMH_00694 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KPHECLMH_00695 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KPHECLMH_00696 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPHECLMH_00697 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KPHECLMH_00698 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPHECLMH_00699 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KPHECLMH_00700 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
KPHECLMH_00701 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KPHECLMH_00702 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KPHECLMH_00703 7.06e-164 - - - C - - - Enoyl-(Acyl carrier protein) reductase
KPHECLMH_00704 5.8e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KPHECLMH_00705 2.61e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPHECLMH_00706 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPHECLMH_00707 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPHECLMH_00708 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KPHECLMH_00709 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KPHECLMH_00710 4.01e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
KPHECLMH_00711 1.72e-209 - - - G - - - Fructosamine kinase
KPHECLMH_00712 2.43e-150 yjcF - - J - - - HAD-hyrolase-like
KPHECLMH_00713 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KPHECLMH_00714 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPHECLMH_00715 2.56e-76 - - - - - - - -
KPHECLMH_00716 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KPHECLMH_00717 5.85e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KPHECLMH_00718 4.82e-107 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KPHECLMH_00719 4.78e-65 - - - - - - - -
KPHECLMH_00720 1.73e-67 - - - - - - - -
KPHECLMH_00723 1.24e-159 int7 - - L - - - Belongs to the 'phage' integrase family
KPHECLMH_00724 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPHECLMH_00725 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPHECLMH_00726 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPHECLMH_00727 5.42e-296 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
KPHECLMH_00728 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPHECLMH_00729 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
KPHECLMH_00730 8.49e-266 pbpX2 - - V - - - Beta-lactamase
KPHECLMH_00731 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KPHECLMH_00732 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KPHECLMH_00733 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPHECLMH_00734 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KPHECLMH_00735 6.88e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KPHECLMH_00736 1.53e-241 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KPHECLMH_00737 1.8e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPHECLMH_00738 2.41e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPHECLMH_00739 1.47e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KPHECLMH_00740 1.24e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KPHECLMH_00741 1.63e-121 - - - - - - - -
KPHECLMH_00742 2.12e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KPHECLMH_00743 0.0 - - - G - - - Major Facilitator
KPHECLMH_00744 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPHECLMH_00745 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPHECLMH_00746 3.28e-63 ylxQ - - J - - - ribosomal protein
KPHECLMH_00747 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
KPHECLMH_00748 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KPHECLMH_00749 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KPHECLMH_00750 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPHECLMH_00751 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KPHECLMH_00752 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KPHECLMH_00753 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KPHECLMH_00754 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPHECLMH_00755 4e-112 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KPHECLMH_00756 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KPHECLMH_00757 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPHECLMH_00758 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KPHECLMH_00759 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
KPHECLMH_00760 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPHECLMH_00761 6.63e-63 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
KPHECLMH_00762 2.11e-171 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
KPHECLMH_00763 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KPHECLMH_00764 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
KPHECLMH_00765 7.68e-48 ynzC - - S - - - UPF0291 protein
KPHECLMH_00766 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KPHECLMH_00767 7.8e-123 - - - - - - - -
KPHECLMH_00768 1.56e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
KPHECLMH_00769 5.61e-98 - - - - - - - -
KPHECLMH_00770 3.81e-87 - - - - - - - -
KPHECLMH_00771 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
KPHECLMH_00772 8.9e-131 - - - L - - - Helix-turn-helix domain
KPHECLMH_00773 5.43e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
KPHECLMH_00774 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KPHECLMH_00775 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_00776 1.96e-293 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
KPHECLMH_00778 4.55e-56 - - - S - - - Bacteriophage holin
KPHECLMH_00779 3.19e-50 - - - S - - - Haemolysin XhlA
KPHECLMH_00780 4.05e-263 - - - M - - - Glycosyl hydrolases family 25
KPHECLMH_00781 1.97e-32 - - - - - - - -
KPHECLMH_00782 2.5e-100 - - - - - - - -
KPHECLMH_00786 0.0 - - - S - - - Phage minor structural protein
KPHECLMH_00787 0.0 - - - S - - - Phage tail protein
KPHECLMH_00788 0.0 - - - S - - - peptidoglycan catabolic process
KPHECLMH_00789 1.12e-05 - - - - - - - -
KPHECLMH_00791 3.67e-91 - - - S - - - Phage tail tube protein
KPHECLMH_00792 3.57e-33 - - - - - - - -
KPHECLMH_00793 1.54e-49 - - - - - - - -
KPHECLMH_00794 2.81e-31 - - - S - - - Phage head-tail joining protein
KPHECLMH_00795 2.28e-66 - - - S - - - Phage gp6-like head-tail connector protein
KPHECLMH_00796 1.31e-269 - - - S - - - peptidase activity
KPHECLMH_00797 5.99e-164 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
KPHECLMH_00798 1.47e-285 - - - S - - - Phage portal protein
KPHECLMH_00799 9.49e-35 - - - S - - - Protein of unknown function (DUF1056)
KPHECLMH_00800 0.0 - - - S - - - Phage Terminase
KPHECLMH_00801 1.91e-104 - - - S - - - Phage terminase, small subunit
KPHECLMH_00802 2.51e-111 - - - L - - - HNH nucleases
KPHECLMH_00803 4.49e-17 - - - V - - - HNH nucleases
KPHECLMH_00805 1.96e-83 - - - S - - - Transcriptional regulator, RinA family
KPHECLMH_00806 6.63e-41 - - - - - - - -
KPHECLMH_00807 1.23e-49 - - - - - - - -
KPHECLMH_00808 1.33e-40 - - - S - - - YopX protein
KPHECLMH_00812 5.34e-31 - - - - - - - -
KPHECLMH_00814 6e-211 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
KPHECLMH_00815 3.01e-95 - - - L - - - DnaD domain protein
KPHECLMH_00818 2.56e-22 - - - - - - - -
KPHECLMH_00822 1.38e-07 - - - - - - - -
KPHECLMH_00825 6.04e-87 - - - S - - - DNA binding
KPHECLMH_00827 2.9e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
KPHECLMH_00830 4.16e-51 - - - S - - - Membrane
KPHECLMH_00837 4.57e-68 int3 - - L - - - Belongs to the 'phage' integrase family
KPHECLMH_00838 1.75e-43 - - - - - - - -
KPHECLMH_00839 6.34e-178 - - - Q - - - Methyltransferase
KPHECLMH_00840 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
KPHECLMH_00841 2.25e-267 - - - EGP - - - Major facilitator Superfamily
KPHECLMH_00842 3.58e-129 - - - K - - - Helix-turn-helix domain
KPHECLMH_00843 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPHECLMH_00844 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KPHECLMH_00845 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
KPHECLMH_00846 5.83e-179 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_00847 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KPHECLMH_00848 1.34e-61 - - - - - - - -
KPHECLMH_00849 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPHECLMH_00850 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
KPHECLMH_00851 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KPHECLMH_00852 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
KPHECLMH_00853 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
KPHECLMH_00854 0.0 cps4J - - S - - - MatE
KPHECLMH_00855 3.4e-228 cps4I - - M - - - Glycosyltransferase like family 2
KPHECLMH_00856 2.71e-297 - - - - - - - -
KPHECLMH_00857 2.26e-243 cps4G - - M - - - Glycosyltransferase Family 4
KPHECLMH_00858 6.63e-258 cps4F - - M - - - Glycosyl transferases group 1
KPHECLMH_00859 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
KPHECLMH_00860 7.15e-230 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
KPHECLMH_00861 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
KPHECLMH_00862 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
KPHECLMH_00863 8.45e-162 epsB - - M - - - biosynthesis protein
KPHECLMH_00864 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KPHECLMH_00865 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_00866 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KPHECLMH_00867 5.12e-31 - - - - - - - -
KPHECLMH_00868 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
KPHECLMH_00869 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
KPHECLMH_00870 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KPHECLMH_00871 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPHECLMH_00872 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPHECLMH_00873 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPHECLMH_00874 5.89e-204 - - - S - - - Tetratricopeptide repeat
KPHECLMH_00875 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPHECLMH_00876 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPHECLMH_00877 4.48e-261 - - - EGP - - - Major Facilitator Superfamily
KPHECLMH_00878 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPHECLMH_00879 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KPHECLMH_00880 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KPHECLMH_00881 9.6e-121 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KPHECLMH_00882 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KPHECLMH_00883 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KPHECLMH_00884 6.29e-163 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
KPHECLMH_00885 8.61e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KPHECLMH_00886 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPHECLMH_00887 7.08e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
KPHECLMH_00888 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
KPHECLMH_00889 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KPHECLMH_00890 1.19e-259 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KPHECLMH_00891 0.0 - - - - - - - -
KPHECLMH_00892 0.0 icaA - - M - - - Glycosyl transferase family group 2
KPHECLMH_00893 9.51e-135 - - - - - - - -
KPHECLMH_00894 4.46e-257 - - - - - - - -
KPHECLMH_00895 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KPHECLMH_00896 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
KPHECLMH_00897 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
KPHECLMH_00898 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
KPHECLMH_00899 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KPHECLMH_00900 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPHECLMH_00901 8.65e-228 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
KPHECLMH_00902 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KPHECLMH_00903 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPHECLMH_00904 6.45e-111 - - - - - - - -
KPHECLMH_00905 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
KPHECLMH_00906 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPHECLMH_00907 3.45e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KPHECLMH_00908 2.16e-39 - - - - - - - -
KPHECLMH_00909 4.26e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KPHECLMH_00910 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPHECLMH_00911 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KPHECLMH_00912 1.02e-155 - - - S - - - repeat protein
KPHECLMH_00913 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
KPHECLMH_00914 0.0 - - - N - - - domain, Protein
KPHECLMH_00915 1.66e-246 - - - S - - - Bacterial protein of unknown function (DUF916)
KPHECLMH_00916 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
KPHECLMH_00917 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
KPHECLMH_00918 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
KPHECLMH_00919 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KPHECLMH_00920 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
KPHECLMH_00921 4.88e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KPHECLMH_00922 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPHECLMH_00923 7.74e-47 - - - - - - - -
KPHECLMH_00924 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KPHECLMH_00925 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KPHECLMH_00926 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPHECLMH_00927 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
KPHECLMH_00928 2.06e-187 ylmH - - S - - - S4 domain protein
KPHECLMH_00929 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
KPHECLMH_00930 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KPHECLMH_00931 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPHECLMH_00932 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KPHECLMH_00933 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KPHECLMH_00934 1.67e-251 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPHECLMH_00935 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPHECLMH_00936 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPHECLMH_00937 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KPHECLMH_00938 7.01e-76 ftsL - - D - - - Cell division protein FtsL
KPHECLMH_00939 7.08e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KPHECLMH_00940 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KPHECLMH_00941 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
KPHECLMH_00942 4.1e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KPHECLMH_00943 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KPHECLMH_00944 1.41e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPHECLMH_00945 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
KPHECLMH_00946 3.59e-301 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KPHECLMH_00948 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
KPHECLMH_00949 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPHECLMH_00960 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
KPHECLMH_00961 2.22e-237 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
KPHECLMH_00962 5.09e-124 - - - - - - - -
KPHECLMH_00963 9.14e-122 - - - K - - - Acetyltransferase (GNAT) domain
KPHECLMH_00964 1.04e-172 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
KPHECLMH_00966 1.24e-144 - - - K - - - helix_turn_helix, arabinose operon control protein
KPHECLMH_00967 4.86e-185 lipA - - I - - - Carboxylesterase family
KPHECLMH_00968 1.13e-153 - - - P - - - Major Facilitator Superfamily
KPHECLMH_00969 1.03e-43 - - - P - - - Major Facilitator Superfamily
KPHECLMH_00970 4.2e-139 - - - GK - - - ROK family
KPHECLMH_00971 1.88e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KPHECLMH_00972 2.95e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KPHECLMH_00973 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KPHECLMH_00974 3.75e-214 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KPHECLMH_00975 2.67e-180 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KPHECLMH_00976 8.94e-167 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KPHECLMH_00977 3.35e-157 - - - - - - - -
KPHECLMH_00978 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPHECLMH_00979 0.0 mdr - - EGP - - - Major Facilitator
KPHECLMH_00980 4.46e-148 - - - N - - - Cell shape-determining protein MreB
KPHECLMH_00982 0.0 - - - S - - - Pfam Methyltransferase
KPHECLMH_00983 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KPHECLMH_00984 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KPHECLMH_00985 9.32e-40 - - - - - - - -
KPHECLMH_00986 3.03e-122 mraW1 - - J - - - Putative rRNA methylase
KPHECLMH_00987 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KPHECLMH_00988 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KPHECLMH_00989 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KPHECLMH_00990 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KPHECLMH_00991 8.69e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPHECLMH_00992 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
KPHECLMH_00993 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
KPHECLMH_00994 1.24e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
KPHECLMH_00995 1.13e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_00996 6.16e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_00997 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KPHECLMH_00998 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KPHECLMH_00999 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
KPHECLMH_01000 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KPHECLMH_01001 1.7e-314 XK27_06930 - - V ko:K01421 - ko00000 domain protein
KPHECLMH_01003 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KPHECLMH_01004 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_01005 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
KPHECLMH_01007 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPHECLMH_01008 3.01e-84 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_01009 1.64e-151 - - - GM - - - NAD(P)H-binding
KPHECLMH_01010 2.38e-159 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KPHECLMH_01011 2.3e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPHECLMH_01012 7.83e-140 - - - - - - - -
KPHECLMH_01013 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KPHECLMH_01014 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KPHECLMH_01015 5.37e-74 - - - - - - - -
KPHECLMH_01016 4.56e-78 - - - - - - - -
KPHECLMH_01017 1.23e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
KPHECLMH_01018 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_01019 8.82e-119 - - - - - - - -
KPHECLMH_01020 7.12e-62 - - - - - - - -
KPHECLMH_01021 0.0 uvrA2 - - L - - - ABC transporter
KPHECLMH_01024 4.29e-87 - - - - - - - -
KPHECLMH_01025 9.03e-16 - - - - - - - -
KPHECLMH_01026 3.89e-237 - - - - - - - -
KPHECLMH_01027 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
KPHECLMH_01028 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
KPHECLMH_01029 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KPHECLMH_01030 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPHECLMH_01031 0.0 - - - S - - - Protein conserved in bacteria
KPHECLMH_01032 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
KPHECLMH_01033 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
KPHECLMH_01034 2.97e-224 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
KPHECLMH_01035 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
KPHECLMH_01036 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
KPHECLMH_01037 2.69e-316 dinF - - V - - - MatE
KPHECLMH_01038 1.79e-42 - - - - - - - -
KPHECLMH_01041 8.2e-102 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
KPHECLMH_01042 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KPHECLMH_01043 4.64e-106 - - - - - - - -
KPHECLMH_01044 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KPHECLMH_01045 6.25e-138 - - - - - - - -
KPHECLMH_01046 0.0 celR - - K - - - PRD domain
KPHECLMH_01047 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
KPHECLMH_01048 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
KPHECLMH_01049 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPHECLMH_01050 4.85e-284 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_01051 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_01052 7.06e-271 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
KPHECLMH_01053 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
KPHECLMH_01054 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPHECLMH_01055 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
KPHECLMH_01056 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
KPHECLMH_01057 2.27e-270 arcT - - E - - - Aminotransferase
KPHECLMH_01058 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KPHECLMH_01059 2.43e-18 - - - - - - - -
KPHECLMH_01060 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KPHECLMH_01061 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
KPHECLMH_01062 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
KPHECLMH_01063 0.0 yhaN - - L - - - AAA domain
KPHECLMH_01064 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
KPHECLMH_01065 3.51e-271 - - - - - - - -
KPHECLMH_01066 1.98e-232 - - - M - - - Peptidase family S41
KPHECLMH_01067 6.59e-227 - - - K - - - LysR substrate binding domain
KPHECLMH_01068 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
KPHECLMH_01069 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KPHECLMH_01070 4.43e-129 - - - - - - - -
KPHECLMH_01071 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
KPHECLMH_01072 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
KPHECLMH_01073 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KPHECLMH_01074 4.29e-26 - - - S - - - NUDIX domain
KPHECLMH_01075 0.0 - - - S - - - membrane
KPHECLMH_01076 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPHECLMH_01077 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KPHECLMH_01078 1.03e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KPHECLMH_01079 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KPHECLMH_01080 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
KPHECLMH_01081 1.96e-137 - - - - - - - -
KPHECLMH_01082 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
KPHECLMH_01083 5.71e-145 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01084 3e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
KPHECLMH_01085 0.0 - - - - - - - -
KPHECLMH_01086 1.65e-80 - - - - - - - -
KPHECLMH_01087 9.64e-248 - - - S - - - Fn3-like domain
KPHECLMH_01088 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_01089 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_01090 1.19e-151 draG - - O - - - ADP-ribosylglycohydrolase
KPHECLMH_01091 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KPHECLMH_01092 9.6e-73 - - - - - - - -
KPHECLMH_01093 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
KPHECLMH_01094 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01095 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_01096 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
KPHECLMH_01097 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPHECLMH_01098 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
KPHECLMH_01099 1.29e-148 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPHECLMH_01100 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KPHECLMH_01101 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KPHECLMH_01102 3.04e-29 - - - S - - - Virus attachment protein p12 family
KPHECLMH_01103 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
KPHECLMH_01104 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
KPHECLMH_01105 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KPHECLMH_01106 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
KPHECLMH_01107 3.17e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPHECLMH_01108 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KPHECLMH_01109 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KPHECLMH_01110 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
KPHECLMH_01111 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KPHECLMH_01112 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KPHECLMH_01113 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPHECLMH_01114 1.85e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KPHECLMH_01115 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPHECLMH_01116 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPHECLMH_01117 8.92e-317 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
KPHECLMH_01118 4.97e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KPHECLMH_01119 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPHECLMH_01120 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPHECLMH_01121 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KPHECLMH_01122 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPHECLMH_01123 1.13e-73 - - - - - - - -
KPHECLMH_01124 2.35e-305 - - - L ko:K07478 - ko00000 AAA C-terminal domain
KPHECLMH_01125 1.67e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KPHECLMH_01126 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
KPHECLMH_01127 2.79e-174 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KPHECLMH_01128 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
KPHECLMH_01129 4.45e-114 - - - - - - - -
KPHECLMH_01130 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
KPHECLMH_01131 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
KPHECLMH_01132 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
KPHECLMH_01133 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPHECLMH_01134 1.71e-149 yqeK - - H - - - Hydrolase, HD family
KPHECLMH_01135 1.02e-74 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPHECLMH_01136 3.3e-180 yqeM - - Q - - - Methyltransferase
KPHECLMH_01137 1.76e-279 ylbM - - S - - - Belongs to the UPF0348 family
KPHECLMH_01138 1.05e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KPHECLMH_01139 2.06e-122 - - - S - - - Peptidase propeptide and YPEB domain
KPHECLMH_01140 1.13e-225 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPHECLMH_01141 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPHECLMH_01142 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KPHECLMH_01143 1.38e-155 csrR - - K - - - response regulator
KPHECLMH_01144 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPHECLMH_01145 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
KPHECLMH_01146 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
KPHECLMH_01147 9.59e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KPHECLMH_01148 1.77e-122 - - - S - - - SdpI/YhfL protein family
KPHECLMH_01149 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPHECLMH_01150 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KPHECLMH_01151 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPHECLMH_01152 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KPHECLMH_01153 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
KPHECLMH_01154 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPHECLMH_01155 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPHECLMH_01156 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPHECLMH_01157 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KPHECLMH_01158 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPHECLMH_01159 3.78e-143 - - - S - - - membrane
KPHECLMH_01160 2.33e-98 - - - K - - - LytTr DNA-binding domain
KPHECLMH_01161 2.5e-71 yneR - - S - - - Belongs to the HesB IscA family
KPHECLMH_01162 0.0 - - - S - - - membrane
KPHECLMH_01163 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KPHECLMH_01164 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KPHECLMH_01165 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPHECLMH_01166 2.03e-152 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
KPHECLMH_01167 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
KPHECLMH_01168 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KPHECLMH_01169 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
KPHECLMH_01170 1.15e-89 yqhL - - P - - - Rhodanese-like protein
KPHECLMH_01171 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
KPHECLMH_01172 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
KPHECLMH_01173 3.8e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPHECLMH_01174 1.57e-84 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
KPHECLMH_01175 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KPHECLMH_01176 1.77e-205 - - - - - - - -
KPHECLMH_01177 1.34e-232 - - - - - - - -
KPHECLMH_01178 2.92e-126 - - - S - - - Protein conserved in bacteria
KPHECLMH_01179 1.27e-72 - - - - - - - -
KPHECLMH_01180 2.97e-41 - - - - - - - -
KPHECLMH_01183 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
KPHECLMH_01184 2.08e-92 - - - S - - - LuxR family transcriptional regulator
KPHECLMH_01185 3.42e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
KPHECLMH_01187 5.37e-117 - - - F - - - NUDIX domain
KPHECLMH_01188 4.87e-205 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01189 7.53e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPHECLMH_01190 0.0 FbpA - - K - - - Fibronectin-binding protein
KPHECLMH_01191 1.97e-87 - - - K - - - Transcriptional regulator
KPHECLMH_01192 1.11e-205 - - - S - - - EDD domain protein, DegV family
KPHECLMH_01193 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
KPHECLMH_01194 4.81e-169 - - - S - - - Protein of unknown function (DUF975)
KPHECLMH_01195 1.18e-32 - - - - - - - -
KPHECLMH_01196 2.37e-65 - - - - - - - -
KPHECLMH_01197 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
KPHECLMH_01198 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
KPHECLMH_01200 2.21e-66 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
KPHECLMH_01201 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
KPHECLMH_01202 1.74e-175 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
KPHECLMH_01203 5.02e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KPHECLMH_01204 2.79e-181 - - - - - - - -
KPHECLMH_01205 7.79e-78 - - - - - - - -
KPHECLMH_01206 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KPHECLMH_01207 1.12e-288 - - - - - - - -
KPHECLMH_01208 1.62e-161 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KPHECLMH_01209 2.65e-246 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KPHECLMH_01210 2.09e-270 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPHECLMH_01211 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPHECLMH_01212 5.9e-57 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KPHECLMH_01213 4.69e-40 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KPHECLMH_01214 4.26e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_01215 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
KPHECLMH_01216 3.22e-87 - - - - - - - -
KPHECLMH_01217 1.68e-310 - - - M - - - Glycosyl transferase family group 2
KPHECLMH_01218 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KPHECLMH_01219 4.19e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
KPHECLMH_01220 1.07e-43 - - - S - - - YozE SAM-like fold
KPHECLMH_01221 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPHECLMH_01222 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KPHECLMH_01223 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KPHECLMH_01224 3.82e-228 - - - K - - - Transcriptional regulator
KPHECLMH_01225 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPHECLMH_01226 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPHECLMH_01227 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPHECLMH_01228 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KPHECLMH_01229 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KPHECLMH_01230 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KPHECLMH_01231 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
KPHECLMH_01232 1.89e-316 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPHECLMH_01233 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPHECLMH_01234 7.78e-201 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KPHECLMH_01235 4.11e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPHECLMH_01236 3.74e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPHECLMH_01238 5.13e-292 XK27_05470 - - E - - - Methionine synthase
KPHECLMH_01239 7.05e-219 cpsY - - K - - - Transcriptional regulator, LysR family
KPHECLMH_01240 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
KPHECLMH_01241 3.53e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
KPHECLMH_01242 1.74e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
KPHECLMH_01243 0.0 qacA - - EGP - - - Major Facilitator
KPHECLMH_01244 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KPHECLMH_01245 1.55e-46 yozE - - S - - - Belongs to the UPF0346 family
KPHECLMH_01246 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
KPHECLMH_01247 5.66e-207 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
KPHECLMH_01248 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
KPHECLMH_01249 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPHECLMH_01250 1.92e-240 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPHECLMH_01251 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01252 6.46e-109 - - - - - - - -
KPHECLMH_01253 1.27e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KPHECLMH_01254 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KPHECLMH_01255 1.06e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KPHECLMH_01256 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
KPHECLMH_01257 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPHECLMH_01258 6.87e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KPHECLMH_01259 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KPHECLMH_01260 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KPHECLMH_01261 9.99e-39 - - - M - - - Lysin motif
KPHECLMH_01262 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KPHECLMH_01263 1.16e-243 - - - S - - - Helix-turn-helix domain
KPHECLMH_01264 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPHECLMH_01265 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KPHECLMH_01266 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPHECLMH_01267 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPHECLMH_01268 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPHECLMH_01269 1.27e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
KPHECLMH_01270 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
KPHECLMH_01271 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
KPHECLMH_01272 6.16e-48 - - - - - - - -
KPHECLMH_01273 5.79e-21 - - - - - - - -
KPHECLMH_01274 1.29e-54 - - - S - - - transglycosylase associated protein
KPHECLMH_01275 4e-40 - - - S - - - CsbD-like
KPHECLMH_01276 1.06e-53 - - - - - - - -
KPHECLMH_01277 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KPHECLMH_01278 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KPHECLMH_01279 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KPHECLMH_01280 2.99e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
KPHECLMH_01281 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
KPHECLMH_01282 8.78e-67 - - - - - - - -
KPHECLMH_01283 3.93e-59 - - - - - - - -
KPHECLMH_01284 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPHECLMH_01285 0.0 - - - E ko:K03294 - ko00000 Amino Acid
KPHECLMH_01286 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KPHECLMH_01287 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
KPHECLMH_01288 1.38e-156 - - - S - - - Domain of unknown function (DUF4767)
KPHECLMH_01289 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KPHECLMH_01290 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KPHECLMH_01291 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KPHECLMH_01292 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KPHECLMH_01293 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KPHECLMH_01294 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KPHECLMH_01295 2.1e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
KPHECLMH_01296 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KPHECLMH_01297 1.03e-106 ypmB - - S - - - protein conserved in bacteria
KPHECLMH_01298 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KPHECLMH_01299 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KPHECLMH_01300 3.25e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
KPHECLMH_01302 3.29e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPHECLMH_01303 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_01304 1.58e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KPHECLMH_01305 5.32e-109 - - - T - - - Universal stress protein family
KPHECLMH_01306 5.48e-140 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_01307 1.02e-216 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_01308 8.06e-234 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KPHECLMH_01309 3.27e-228 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KPHECLMH_01310 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
KPHECLMH_01311 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KPHECLMH_01312 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
KPHECLMH_01313 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KPHECLMH_01315 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KPHECLMH_01316 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_01317 3.65e-308 - - - P - - - Major Facilitator Superfamily
KPHECLMH_01318 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KPHECLMH_01319 1.48e-83 - - - S - - - SnoaL-like domain
KPHECLMH_01320 9.63e-307 - - - M - - - Glycosyltransferase, group 2 family protein
KPHECLMH_01321 3.46e-267 mccF - - V - - - LD-carboxypeptidase
KPHECLMH_01322 8.75e-72 - - - K - - - Acetyltransferase (GNAT) domain
KPHECLMH_01323 1.23e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
KPHECLMH_01324 1.38e-232 - - - V - - - LD-carboxypeptidase
KPHECLMH_01325 5.07e-158 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KPHECLMH_01326 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KPHECLMH_01327 6.79e-249 - - - - - - - -
KPHECLMH_01328 1.23e-185 - - - S - - - hydrolase activity, acting on ester bonds
KPHECLMH_01329 8.53e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
KPHECLMH_01330 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
KPHECLMH_01331 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
KPHECLMH_01332 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KPHECLMH_01333 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KPHECLMH_01334 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KPHECLMH_01335 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPHECLMH_01336 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
KPHECLMH_01337 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KPHECLMH_01338 2.01e-145 - - - G - - - Phosphoglycerate mutase family
KPHECLMH_01339 7.75e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
KPHECLMH_01341 0.0 - - - V - - - DNA restriction-modification system
KPHECLMH_01342 1.72e-70 - - - - - - - -
KPHECLMH_01343 6.58e-225 - - - L - - - Initiator Replication protein
KPHECLMH_01344 4.18e-39 - - - - - - - -
KPHECLMH_01345 6.76e-83 - - - - - - - -
KPHECLMH_01346 5.35e-139 - - - L - - - Integrase
KPHECLMH_01347 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
KPHECLMH_01348 1.82e-77 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
KPHECLMH_01349 4.09e-69 - - - K - - - Helix-turn-helix XRE-family like proteins
KPHECLMH_01350 3.38e-05 - - - L - - - helicase superfamily c-terminal domain
KPHECLMH_01351 1.04e-220 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
KPHECLMH_01352 9.53e-100 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
KPHECLMH_01353 1.85e-201 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
KPHECLMH_01354 1.06e-205 - - - K - - - LysR substrate binding domain
KPHECLMH_01355 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KPHECLMH_01356 0.0 - - - S - - - MucBP domain
KPHECLMH_01357 1.78e-139 - - - - - - - -
KPHECLMH_01358 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KPHECLMH_01359 1.28e-77 - - - S - - - Enterocin A Immunity
KPHECLMH_01360 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
KPHECLMH_01361 1.72e-215 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
KPHECLMH_01362 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
KPHECLMH_01363 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
KPHECLMH_01364 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
KPHECLMH_01365 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
KPHECLMH_01366 1.03e-34 - - - - - - - -
KPHECLMH_01367 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
KPHECLMH_01368 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
KPHECLMH_01369 1.93e-208 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
KPHECLMH_01370 3.85e-234 - - - D ko:K06889 - ko00000 Alpha beta
KPHECLMH_01371 1.01e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KPHECLMH_01372 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
KPHECLMH_01373 2.05e-72 - - - S - - - Enterocin A Immunity
KPHECLMH_01374 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPHECLMH_01375 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPHECLMH_01376 4.17e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPHECLMH_01377 8.2e-235 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPHECLMH_01378 6.22e-201 - - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPHECLMH_01379 0.0 amiC - - U ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_01380 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KPHECLMH_01381 5.9e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KPHECLMH_01382 1.33e-77 - - - - - - - -
KPHECLMH_01383 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KPHECLMH_01384 2.1e-41 - - - - - - - -
KPHECLMH_01385 2.65e-245 ampC - - V - - - Beta-lactamase
KPHECLMH_01386 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KPHECLMH_01387 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
KPHECLMH_01388 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
KPHECLMH_01389 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KPHECLMH_01390 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPHECLMH_01391 5.71e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPHECLMH_01392 7.28e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KPHECLMH_01393 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPHECLMH_01394 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPHECLMH_01395 4.12e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
KPHECLMH_01396 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KPHECLMH_01397 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPHECLMH_01398 1.27e-75 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPHECLMH_01399 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPHECLMH_01400 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPHECLMH_01401 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPHECLMH_01402 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPHECLMH_01403 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KPHECLMH_01404 2.4e-314 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPHECLMH_01405 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KPHECLMH_01406 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
KPHECLMH_01407 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KPHECLMH_01408 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
KPHECLMH_01409 5.05e-279 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KPHECLMH_01410 3.09e-62 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
KPHECLMH_01411 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPHECLMH_01412 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_01413 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KPHECLMH_01414 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KPHECLMH_01415 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
KPHECLMH_01416 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KPHECLMH_01417 3.78e-272 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KPHECLMH_01418 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
KPHECLMH_01419 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
KPHECLMH_01420 3.3e-260 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KPHECLMH_01421 2.37e-107 uspA - - T - - - universal stress protein
KPHECLMH_01422 1.34e-52 - - - - - - - -
KPHECLMH_01423 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KPHECLMH_01424 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KPHECLMH_01425 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_01426 2.6e-141 - - - S - - - Protein of unknown function (DUF1648)
KPHECLMH_01427 4e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KPHECLMH_01428 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
KPHECLMH_01429 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPHECLMH_01430 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KPHECLMH_01431 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPHECLMH_01432 4.29e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KPHECLMH_01433 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPHECLMH_01434 7.78e-300 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
KPHECLMH_01435 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPHECLMH_01436 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPHECLMH_01437 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KPHECLMH_01438 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
KPHECLMH_01439 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
KPHECLMH_01440 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KPHECLMH_01441 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
KPHECLMH_01442 5.41e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KPHECLMH_01443 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KPHECLMH_01444 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KPHECLMH_01445 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01446 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KPHECLMH_01447 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KPHECLMH_01448 5.88e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
KPHECLMH_01449 0.0 ymfH - - S - - - Peptidase M16
KPHECLMH_01450 4.71e-171 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
KPHECLMH_01451 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPHECLMH_01452 1.56e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KPHECLMH_01453 9.9e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPHECLMH_01454 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KPHECLMH_01455 1.77e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
KPHECLMH_01456 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KPHECLMH_01457 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPHECLMH_01458 2.1e-162 - - - L ko:K07487 - ko00000 Transposase
KPHECLMH_01459 7.87e-158 zmp2 - - O - - - Zinc-dependent metalloprotease
KPHECLMH_01460 7.78e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPHECLMH_01461 8.57e-227 - - - EG - - - EamA-like transporter family
KPHECLMH_01462 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
KPHECLMH_01463 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KPHECLMH_01464 5e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
KPHECLMH_01465 3.66e-184 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPHECLMH_01466 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
KPHECLMH_01467 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
KPHECLMH_01468 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPHECLMH_01469 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KPHECLMH_01470 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KPHECLMH_01471 0.0 levR - - K - - - Sigma-54 interaction domain
KPHECLMH_01472 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
KPHECLMH_01473 8.89e-218 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
KPHECLMH_01474 2.43e-174 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
KPHECLMH_01475 2.63e-217 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KPHECLMH_01476 2.27e-197 - - - G - - - Peptidase_C39 like family
KPHECLMH_01477 1.05e-97 - - - M - - - Glycosyl hydrolases family 25
KPHECLMH_01478 2.52e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
KPHECLMH_01480 2.09e-51 - - - - - - - -
KPHECLMH_01482 7.54e-23 - - - S - - - Protein of unknown function (DUF1617)
KPHECLMH_01483 4.6e-168 - - - LM - - - DNA recombination
KPHECLMH_01485 1.5e-193 - - - L - - - Phage tail tape measure protein TP901
KPHECLMH_01488 7.59e-44 - - - S - - - Phage tail tube protein
KPHECLMH_01489 1.3e-28 - - - - - - - -
KPHECLMH_01490 1.12e-32 - - - - - - - -
KPHECLMH_01491 3.04e-32 - - - - - - - -
KPHECLMH_01492 3.26e-19 - - - - - - - -
KPHECLMH_01493 5.26e-134 - - - S - - - Phage capsid family
KPHECLMH_01494 2.45e-72 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
KPHECLMH_01495 1.47e-126 - - - S - - - Phage portal protein
KPHECLMH_01496 3.35e-213 - - - S - - - Terminase
KPHECLMH_01497 3.41e-13 - - - - - - - -
KPHECLMH_01501 1.06e-215 - - - - - - - -
KPHECLMH_01502 3.33e-170 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
KPHECLMH_01503 3.33e-43 - - - - - - - -
KPHECLMH_01505 1.09e-74 - - - - - - - -
KPHECLMH_01511 1.13e-47 - - - S - - - hydrolase activity, acting on ester bonds
KPHECLMH_01512 2.59e-165 - - - S ko:K06919 - ko00000 Virulence-associated protein E
KPHECLMH_01513 5.45e-96 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
KPHECLMH_01514 1.6e-28 - - - - - - - -
KPHECLMH_01515 9.97e-94 - - - L - - - AAA domain
KPHECLMH_01516 1.22e-195 - - - S - - - helicase activity
KPHECLMH_01517 6.79e-55 - - - S - - - Siphovirus Gp157
KPHECLMH_01525 1.03e-11 - - - - - - - -
KPHECLMH_01526 2.71e-91 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2321)
KPHECLMH_01527 1.91e-27 - - - - - - - -
KPHECLMH_01534 6.78e-34 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KPHECLMH_01535 3.81e-172 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KPHECLMH_01536 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KPHECLMH_01537 1.46e-126 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01538 6.24e-215 - - - GM - - - NmrA-like family
KPHECLMH_01539 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KPHECLMH_01540 0.0 - - - M - - - Glycosyl hydrolases family 25
KPHECLMH_01541 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
KPHECLMH_01542 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
KPHECLMH_01543 3.27e-170 - - - S - - - KR domain
KPHECLMH_01544 1.66e-125 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01545 2.01e-243 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
KPHECLMH_01546 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
KPHECLMH_01547 1.33e-227 ydhF - - S - - - Aldo keto reductase
KPHECLMH_01548 0.0 yfjF - - U - - - Sugar (and other) transporter
KPHECLMH_01549 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01550 8.96e-196 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KPHECLMH_01551 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KPHECLMH_01552 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPHECLMH_01553 1.11e-217 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPHECLMH_01554 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01555 9.16e-209 - - - GM - - - NmrA-like family
KPHECLMH_01556 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_01557 5.69e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KPHECLMH_01558 3.48e-44 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KPHECLMH_01559 8.04e-128 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
KPHECLMH_01560 6.41e-84 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_01561 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KPHECLMH_01562 3.38e-74 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KPHECLMH_01563 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
KPHECLMH_01564 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_01565 3.03e-315 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_01566 2.09e-85 - - - - - - - -
KPHECLMH_01567 5.15e-16 - - - - - - - -
KPHECLMH_01568 3.24e-53 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KPHECLMH_01569 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_01570 6.92e-76 - - - S - - - Protein of unknown function (DUF1093)
KPHECLMH_01571 2.23e-279 - - - S - - - Membrane
KPHECLMH_01572 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
KPHECLMH_01573 1.31e-139 yoaZ - - S - - - intracellular protease amidase
KPHECLMH_01574 2.33e-56 - - - K - - - HxlR-like helix-turn-helix
KPHECLMH_01575 5.36e-76 - - - - - - - -
KPHECLMH_01576 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_01577 5.31e-66 - - - K - - - Helix-turn-helix domain
KPHECLMH_01578 2.23e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
KPHECLMH_01579 2e-62 - - - K - - - Helix-turn-helix domain
KPHECLMH_01580 7.8e-115 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPHECLMH_01581 2.5e-66 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPHECLMH_01582 7.85e-114 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01583 6.79e-53 - - - - - - - -
KPHECLMH_01584 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPHECLMH_01585 1.6e-233 ydbI - - K - - - AI-2E family transporter
KPHECLMH_01586 9.28e-271 xylR - - GK - - - ROK family
KPHECLMH_01587 2.42e-143 - - - - - - - -
KPHECLMH_01588 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KPHECLMH_01589 1.41e-211 - - - - - - - -
KPHECLMH_01590 1.86e-256 pkn2 - - KLT - - - Protein tyrosine kinase
KPHECLMH_01591 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
KPHECLMH_01592 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
KPHECLMH_01593 6.05e-93 - - - S - - - Psort location Cytoplasmic, score
KPHECLMH_01594 8.78e-33 - - - - - - - -
KPHECLMH_01595 3.37e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
KPHECLMH_01596 5.93e-73 - - - S - - - branched-chain amino acid
KPHECLMH_01597 2.05e-167 - - - E - - - branched-chain amino acid
KPHECLMH_01598 3.92e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KPHECLMH_01599 6.25e-304 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KPHECLMH_01600 5.61e-273 hpk31 - - T - - - Histidine kinase
KPHECLMH_01601 1.14e-159 vanR - - K - - - response regulator
KPHECLMH_01602 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
KPHECLMH_01603 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KPHECLMH_01604 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPHECLMH_01605 2.02e-159 - - - S - - - Protein of unknown function (DUF1129)
KPHECLMH_01606 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPHECLMH_01607 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
KPHECLMH_01608 7.16e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KPHECLMH_01609 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
KPHECLMH_01610 8.63e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KPHECLMH_01611 7.38e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KPHECLMH_01612 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
KPHECLMH_01613 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KPHECLMH_01614 1.49e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_01615 3.36e-216 - - - K - - - LysR substrate binding domain
KPHECLMH_01616 2.07e-302 - - - EK - - - Aminotransferase, class I
KPHECLMH_01617 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KPHECLMH_01618 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_01619 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01620 7.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KPHECLMH_01621 4.37e-127 - - - KT - - - response to antibiotic
KPHECLMH_01622 2.86e-68 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
KPHECLMH_01623 2.86e-131 - - - S - - - Protein of unknown function (DUF1700)
KPHECLMH_01624 1.13e-200 - - - S - - - Putative adhesin
KPHECLMH_01625 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPHECLMH_01626 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KPHECLMH_01627 6.12e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
KPHECLMH_01628 3.73e-263 - - - S - - - DUF218 domain
KPHECLMH_01629 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KPHECLMH_01630 5.91e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_01631 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPHECLMH_01632 6.26e-101 - - - - - - - -
KPHECLMH_01633 6.34e-193 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
KPHECLMH_01634 5.47e-180 - - - S - - - haloacid dehalogenase-like hydrolase
KPHECLMH_01635 5.22e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KPHECLMH_01636 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
KPHECLMH_01637 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
KPHECLMH_01638 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPHECLMH_01639 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
KPHECLMH_01640 1.5e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPHECLMH_01641 4.08e-101 - - - K - - - MerR family regulatory protein
KPHECLMH_01642 1.52e-199 - - - GM - - - NmrA-like family
KPHECLMH_01643 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPHECLMH_01644 5.08e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
KPHECLMH_01646 2.01e-29 - - - S - - - NADPH-dependent FMN reductase
KPHECLMH_01647 2.77e-64 - - - S - - - NADPH-dependent FMN reductase
KPHECLMH_01648 2.32e-301 - - - S - - - module of peptide synthetase
KPHECLMH_01649 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KPHECLMH_01650 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
KPHECLMH_01651 5.8e-291 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KPHECLMH_01652 3.79e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KPHECLMH_01653 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPHECLMH_01654 8.31e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KPHECLMH_01655 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KPHECLMH_01656 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPHECLMH_01657 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KPHECLMH_01658 5.6e-41 - - - - - - - -
KPHECLMH_01659 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KPHECLMH_01660 2.92e-131 - - - L - - - Integrase
KPHECLMH_01661 3.4e-85 - - - K - - - Winged helix DNA-binding domain
KPHECLMH_01662 5.43e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPHECLMH_01663 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPHECLMH_01664 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPHECLMH_01665 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPHECLMH_01666 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_01667 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
KPHECLMH_01668 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
KPHECLMH_01669 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
KPHECLMH_01670 3.51e-251 - - - M - - - MucBP domain
KPHECLMH_01671 0.0 - - - - - - - -
KPHECLMH_01672 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KPHECLMH_01673 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
KPHECLMH_01674 1.3e-77 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KPHECLMH_01675 3.57e-116 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KPHECLMH_01676 5.58e-305 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KPHECLMH_01677 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
KPHECLMH_01678 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
KPHECLMH_01679 1.13e-257 yueF - - S - - - AI-2E family transporter
KPHECLMH_01680 1.73e-178 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KPHECLMH_01681 5.09e-51 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
KPHECLMH_01682 8.01e-64 - - - K - - - sequence-specific DNA binding
KPHECLMH_01683 1.94e-170 lytE - - M - - - NlpC/P60 family
KPHECLMH_01684 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KPHECLMH_01685 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KPHECLMH_01686 3.29e-169 - - - - - - - -
KPHECLMH_01687 8.02e-130 - - - K - - - DNA-templated transcription, initiation
KPHECLMH_01688 8.39e-38 - - - - - - - -
KPHECLMH_01689 1.95e-41 - - - - - - - -
KPHECLMH_01690 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
KPHECLMH_01691 9.02e-70 - - - - - - - -
KPHECLMH_01692 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
KPHECLMH_01693 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KPHECLMH_01694 2.18e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_01695 0.0 - - - M - - - domain protein
KPHECLMH_01696 5.52e-139 - - - K - - - helix_turn_helix, arabinose operon control protein
KPHECLMH_01697 9.83e-189 cps3J - - M - - - Domain of unknown function (DUF4422)
KPHECLMH_01698 1.28e-253 cps3I - - G - - - Acyltransferase family
KPHECLMH_01699 9.47e-261 cps3H - - - - - - -
KPHECLMH_01700 1.11e-205 cps3F - - - - - - -
KPHECLMH_01701 2.8e-143 cps3E - - - - - - -
KPHECLMH_01702 1.83e-249 cps3D - - - - - - -
KPHECLMH_01703 4.67e-281 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KPHECLMH_01704 5.21e-226 - - - S - - - Glycosyltransferase like family 2
KPHECLMH_01705 2.1e-217 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
KPHECLMH_01706 7.72e-35 - - - S - - - Barstar (barnase inhibitor)
KPHECLMH_01707 8.72e-73 - - - S - - - Immunity protein 63
KPHECLMH_01709 2.32e-152 - - - - - - - -
KPHECLMH_01711 4.82e-56 - - - S - - - ankyrin repeats
KPHECLMH_01713 2.15e-174 - - - L - - - Transposase and inactivated derivatives, IS30 family
KPHECLMH_01714 3.47e-142 - - - - - - - -
KPHECLMH_01715 1.08e-172 - - - - - - - -
KPHECLMH_01716 9.17e-41 - - - - - - - -
KPHECLMH_01717 3.07e-48 - - - - - - - -
KPHECLMH_01718 2.61e-152 - - - - - - - -
KPHECLMH_01720 3.23e-58 - - - - - - - -
KPHECLMH_01721 1.79e-172 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
KPHECLMH_01722 7.28e-175 - - - M - - - domain protein
KPHECLMH_01723 1e-28 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
KPHECLMH_01724 2.34e-105 cps2J - - S - - - Polysaccharide biosynthesis protein
KPHECLMH_01725 5.71e-57 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
KPHECLMH_01726 1.47e-167 cps4I - - M - - - Glycosyltransferase like family 2
KPHECLMH_01727 2.08e-218 - - - - - - - -
KPHECLMH_01728 1.54e-159 cps4G - - M - - - Glycosyltransferase Family 4
KPHECLMH_01729 1.47e-166 cps4F - - M - - - Glycosyl transferases group 1
KPHECLMH_01730 8.38e-160 tuaA - - M - - - Bacterial sugar transferase
KPHECLMH_01731 1.33e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
KPHECLMH_01732 1.69e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
KPHECLMH_01733 6.79e-163 ywqD - - D - - - Capsular exopolysaccharide family
KPHECLMH_01734 8.87e-168 epsB - - M - - - biosynthesis protein
KPHECLMH_01735 3.69e-130 - - - L - - - Integrase
KPHECLMH_01736 3.94e-106 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPHECLMH_01737 7.77e-90 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPHECLMH_01738 5.05e-130 - - - M - - - Parallel beta-helix repeats
KPHECLMH_01739 1.33e-82 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
KPHECLMH_01740 2.02e-214 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KPHECLMH_01741 6.89e-68 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
KPHECLMH_01742 1.4e-62 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPHECLMH_01743 2e-117 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
KPHECLMH_01744 2.34e-99 cps3J - - M - - - Domain of unknown function (DUF4422)
KPHECLMH_01745 1.43e-28 - - - S - - - O-antigen ligase like membrane protein
KPHECLMH_01746 7.12e-09 - - - V - - - Beta-lactamase
KPHECLMH_01747 2.23e-10 cap5B - - D - - - NUBPL iron-transfer P-loop NTPase
KPHECLMH_01749 6.08e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KPHECLMH_01750 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPHECLMH_01751 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KPHECLMH_01752 2.74e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KPHECLMH_01753 2.41e-106 pbpX - - V - - - Beta-lactamase
KPHECLMH_01754 4e-157 pbpX - - V - - - Beta-lactamase
KPHECLMH_01755 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KPHECLMH_01756 1.18e-138 - - - - - - - -
KPHECLMH_01757 7.62e-97 - - - - - - - -
KPHECLMH_01759 1.59e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_01760 5e-310 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_01761 3.93e-99 - - - T - - - Universal stress protein family
KPHECLMH_01763 2.34e-315 yfmL - - L - - - DEAD DEAH box helicase
KPHECLMH_01764 7.89e-245 mocA - - S - - - Oxidoreductase
KPHECLMH_01765 2.54e-42 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KPHECLMH_01766 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
KPHECLMH_01767 7.76e-186 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KPHECLMH_01768 5.63e-196 gntR - - K - - - rpiR family
KPHECLMH_01769 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_01770 1.66e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_01771 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KPHECLMH_01772 1.12e-129 yobS - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01773 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPHECLMH_01774 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
KPHECLMH_01775 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPHECLMH_01776 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPHECLMH_01777 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPHECLMH_01778 9.48e-263 camS - - S - - - sex pheromone
KPHECLMH_01779 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPHECLMH_01780 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KPHECLMH_01781 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KPHECLMH_01782 1.13e-120 yebE - - S - - - UPF0316 protein
KPHECLMH_01783 8.19e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPHECLMH_01784 3.41e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
KPHECLMH_01785 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KPHECLMH_01786 4.92e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
KPHECLMH_01787 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KPHECLMH_01788 3.81e-208 - - - S - - - L,D-transpeptidase catalytic domain
KPHECLMH_01789 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KPHECLMH_01790 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KPHECLMH_01791 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
KPHECLMH_01792 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
KPHECLMH_01793 0.0 - - - S ko:K06889 - ko00000 Alpha beta
KPHECLMH_01794 6.07e-33 - - - - - - - -
KPHECLMH_01795 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPHECLMH_01796 1.54e-228 ydbI - - K - - - AI-2E family transporter
KPHECLMH_01797 1.96e-275 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
KPHECLMH_01798 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KPHECLMH_01799 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
KPHECLMH_01800 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
KPHECLMH_01801 5.98e-72 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_01802 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KPHECLMH_01803 6.62e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
KPHECLMH_01805 8.03e-28 - - - - - - - -
KPHECLMH_01806 3.75e-122 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KPHECLMH_01807 1.37e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
KPHECLMH_01808 3.59e-130 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
KPHECLMH_01809 1.03e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KPHECLMH_01810 1.04e-133 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
KPHECLMH_01811 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KPHECLMH_01812 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPHECLMH_01813 4.08e-107 cvpA - - S - - - Colicin V production protein
KPHECLMH_01814 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KPHECLMH_01815 8.83e-317 - - - EGP - - - Major Facilitator
KPHECLMH_01817 4.54e-54 - - - - - - - -
KPHECLMH_01819 2.63e-90 - - - - - - - -
KPHECLMH_01820 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KPHECLMH_01821 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KPHECLMH_01822 8.12e-306 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
KPHECLMH_01823 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
KPHECLMH_01824 1.06e-184 - - - - - - - -
KPHECLMH_01825 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KPHECLMH_01826 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPHECLMH_01827 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KPHECLMH_01828 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
KPHECLMH_01829 2.21e-56 - - - - - - - -
KPHECLMH_01830 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
KPHECLMH_01831 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KPHECLMH_01832 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
KPHECLMH_01833 7.54e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KPHECLMH_01834 1.17e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KPHECLMH_01835 2.13e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
KPHECLMH_01836 7.87e-243 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
KPHECLMH_01837 7.08e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
KPHECLMH_01838 2.06e-258 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
KPHECLMH_01839 5.16e-271 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
KPHECLMH_01840 4.67e-215 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
KPHECLMH_01841 1.01e-23 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
KPHECLMH_01842 6.14e-53 - - - - - - - -
KPHECLMH_01843 1.93e-289 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_01844 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
KPHECLMH_01845 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
KPHECLMH_01846 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
KPHECLMH_01847 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
KPHECLMH_01848 2.98e-90 - - - - - - - -
KPHECLMH_01849 1.22e-125 - - - - - - - -
KPHECLMH_01850 5.92e-67 - - - - - - - -
KPHECLMH_01851 1.96e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KPHECLMH_01852 2.84e-110 - - - - - - - -
KPHECLMH_01853 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
KPHECLMH_01854 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_01855 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
KPHECLMH_01856 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPHECLMH_01857 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KPHECLMH_01858 3.48e-126 - - - K - - - Helix-turn-helix domain
KPHECLMH_01859 1.37e-283 - - - C - - - FAD dependent oxidoreductase
KPHECLMH_01860 9.01e-221 - - - P - - - Major Facilitator Superfamily
KPHECLMH_01861 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPHECLMH_01862 1.2e-91 - - - - - - - -
KPHECLMH_01863 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPHECLMH_01864 5.3e-202 dkgB - - S - - - reductase
KPHECLMH_01865 2.28e-114 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KPHECLMH_01866 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
KPHECLMH_01867 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KPHECLMH_01868 1.75e-149 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
KPHECLMH_01869 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
KPHECLMH_01870 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPHECLMH_01871 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPHECLMH_01872 3.81e-18 - - - - - - - -
KPHECLMH_01873 3.69e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPHECLMH_01874 4.56e-210 fbpA - - K - - - Domain of unknown function (DUF814)
KPHECLMH_01875 1.35e-78 - - - S - - - Domain of unknown function (DU1801)
KPHECLMH_01876 6.33e-46 - - - - - - - -
KPHECLMH_01877 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
KPHECLMH_01878 1.11e-146 pgm1 - - G - - - phosphoglycerate mutase
KPHECLMH_01879 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPHECLMH_01880 1.19e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPHECLMH_01881 1.08e-101 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KPHECLMH_01882 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_01883 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_01884 2.95e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KPHECLMH_01886 2.18e-285 - - - M - - - domain protein
KPHECLMH_01887 4.44e-183 - - - M - - - domain protein
KPHECLMH_01888 1.72e-212 mleR - - K - - - LysR substrate binding domain
KPHECLMH_01889 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KPHECLMH_01890 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KPHECLMH_01891 1.92e-209 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
KPHECLMH_01892 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KPHECLMH_01893 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
KPHECLMH_01894 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KPHECLMH_01895 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPHECLMH_01896 2.07e-149 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KPHECLMH_01897 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KPHECLMH_01898 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KPHECLMH_01899 2.27e-51 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
KPHECLMH_01900 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_01901 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
KPHECLMH_01902 4.78e-153 - - - S - - - DJ-1/PfpI family
KPHECLMH_01903 7.1e-194 - - - EG - - - EamA-like transporter family
KPHECLMH_01904 2.84e-81 - - - S - - - Protein of unknown function
KPHECLMH_01905 7.44e-51 - - - S - - - Protein of unknown function
KPHECLMH_01906 0.0 fusA1 - - J - - - elongation factor G
KPHECLMH_01907 1.63e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KPHECLMH_01908 1.67e-220 - - - K - - - WYL domain
KPHECLMH_01909 4.35e-165 - - - F - - - glutamine amidotransferase
KPHECLMH_01910 1.36e-105 - - - S - - - ASCH
KPHECLMH_01911 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
KPHECLMH_01912 2.79e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KPHECLMH_01913 9.3e-317 - - - S - - - Putative threonine/serine exporter
KPHECLMH_01914 1.27e-247 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KPHECLMH_01915 1.56e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KPHECLMH_01916 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
KPHECLMH_01917 5.07e-157 ydgI - - C - - - Nitroreductase family
KPHECLMH_01918 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
KPHECLMH_01919 4.06e-211 - - - S - - - KR domain
KPHECLMH_01920 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPHECLMH_01921 2.49e-95 - - - C - - - FMN binding
KPHECLMH_01922 1.46e-204 - - - K - - - LysR family
KPHECLMH_01923 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KPHECLMH_01924 0.0 - - - C - - - FMN_bind
KPHECLMH_01925 7.46e-149 - - - S - - - Elongation factor G-binding protein, N-terminal
KPHECLMH_01926 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
KPHECLMH_01927 1.34e-153 pnb - - C - - - nitroreductase
KPHECLMH_01928 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
KPHECLMH_01929 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KPHECLMH_01930 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
KPHECLMH_01931 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_01932 7.1e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPHECLMH_01933 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
KPHECLMH_01934 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
KPHECLMH_01935 3.54e-195 yycI - - S - - - YycH protein
KPHECLMH_01936 3.55e-313 yycH - - S - - - YycH protein
KPHECLMH_01937 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPHECLMH_01938 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KPHECLMH_01940 2.54e-50 - - - - - - - -
KPHECLMH_01941 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
KPHECLMH_01942 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
KPHECLMH_01943 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
KPHECLMH_01944 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KPHECLMH_01945 8.04e-182 - - - S - - - haloacid dehalogenase-like hydrolase
KPHECLMH_01947 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KPHECLMH_01948 7.84e-103 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KPHECLMH_01949 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KPHECLMH_01950 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KPHECLMH_01951 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
KPHECLMH_01952 5.02e-277 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPHECLMH_01953 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KPHECLMH_01954 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_01956 1.88e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPHECLMH_01957 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPHECLMH_01958 4.96e-289 yttB - - EGP - - - Major Facilitator
KPHECLMH_01959 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KPHECLMH_01960 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KPHECLMH_01961 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KPHECLMH_01962 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPHECLMH_01963 1.59e-95 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPHECLMH_01964 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KPHECLMH_01965 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPHECLMH_01966 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPHECLMH_01967 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPHECLMH_01968 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
KPHECLMH_01969 1.65e-266 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPHECLMH_01970 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPHECLMH_01971 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KPHECLMH_01972 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPHECLMH_01973 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPHECLMH_01974 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_01975 4.56e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
KPHECLMH_01976 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
KPHECLMH_01977 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPHECLMH_01978 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KPHECLMH_01979 1.31e-143 - - - S - - - Cell surface protein
KPHECLMH_01980 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
KPHECLMH_01982 0.0 - - - - - - - -
KPHECLMH_01983 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KPHECLMH_01985 4.63e-215 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KPHECLMH_01986 1.21e-78 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KPHECLMH_01987 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
KPHECLMH_01988 1.64e-202 degV1 - - S - - - DegV family
KPHECLMH_01989 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
KPHECLMH_01990 8.69e-187 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
KPHECLMH_01991 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KPHECLMH_01992 7.43e-130 padR - - K - - - Virulence activator alpha C-term
KPHECLMH_01993 2.51e-103 - - - T - - - Universal stress protein family
KPHECLMH_01994 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KPHECLMH_01995 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KPHECLMH_01996 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPHECLMH_01997 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KPHECLMH_01998 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
KPHECLMH_01999 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
KPHECLMH_02000 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KPHECLMH_02001 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
KPHECLMH_02002 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
KPHECLMH_02003 5.88e-233 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
KPHECLMH_02004 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KPHECLMH_02005 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_02006 5.03e-95 - - - K - - - Transcriptional regulator
KPHECLMH_02007 1.66e-128 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_02008 4.68e-197 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_02009 3.4e-58 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_02010 3.24e-188 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KPHECLMH_02012 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
KPHECLMH_02013 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
KPHECLMH_02014 9.62e-19 - - - - - - - -
KPHECLMH_02015 9.31e-213 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KPHECLMH_02016 7.42e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KPHECLMH_02017 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
KPHECLMH_02018 4.29e-316 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
KPHECLMH_02019 8.48e-37 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
KPHECLMH_02020 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
KPHECLMH_02021 1.06e-16 - - - - - - - -
KPHECLMH_02022 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
KPHECLMH_02023 9.93e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
KPHECLMH_02024 2.28e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
KPHECLMH_02025 1.01e-157 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KPHECLMH_02026 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KPHECLMH_02027 4.66e-197 nanK - - GK - - - ROK family
KPHECLMH_02028 9.03e-173 - - - G - - - Xylose isomerase domain protein TIM barrel
KPHECLMH_02029 2.87e-172 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPHECLMH_02030 1.93e-76 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPHECLMH_02031 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPHECLMH_02032 3.89e-205 - - - I - - - alpha/beta hydrolase fold
KPHECLMH_02033 2.09e-209 - - - I - - - alpha/beta hydrolase fold
KPHECLMH_02034 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
KPHECLMH_02035 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
KPHECLMH_02036 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KPHECLMH_02037 2.13e-145 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
KPHECLMH_02038 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPHECLMH_02039 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPHECLMH_02040 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KPHECLMH_02041 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
KPHECLMH_02042 9.14e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
KPHECLMH_02043 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPHECLMH_02044 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPHECLMH_02045 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
KPHECLMH_02046 1.66e-305 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KPHECLMH_02047 1.02e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KPHECLMH_02048 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPHECLMH_02049 1.74e-184 yxeH - - S - - - hydrolase
KPHECLMH_02050 1.91e-235 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KPHECLMH_02052 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
KPHECLMH_02053 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KPHECLMH_02054 1.08e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
KPHECLMH_02055 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KPHECLMH_02056 2.89e-73 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KPHECLMH_02057 8.55e-116 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KPHECLMH_02058 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPHECLMH_02059 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02060 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02061 4.34e-199 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KPHECLMH_02062 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPHECLMH_02063 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02064 5.33e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
KPHECLMH_02065 2.4e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
KPHECLMH_02066 5.07e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KPHECLMH_02067 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_02068 7.74e-174 - - - K - - - UTRA domain
KPHECLMH_02069 2.16e-199 estA - - S - - - Putative esterase
KPHECLMH_02070 4.93e-82 - - - - - - - -
KPHECLMH_02071 3.06e-260 - - - EGP - - - Major Facilitator Superfamily
KPHECLMH_02072 5.77e-214 - - - K - - - Transcriptional regulator, LysR family
KPHECLMH_02073 4.57e-211 - - - G - - - Xylose isomerase-like TIM barrel
KPHECLMH_02074 6.69e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KPHECLMH_02075 1.64e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPHECLMH_02076 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPHECLMH_02077 3.3e-281 - - - EGP - - - Major Facilitator Superfamily
KPHECLMH_02078 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
KPHECLMH_02079 1.12e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPHECLMH_02080 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KPHECLMH_02081 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPHECLMH_02082 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KPHECLMH_02083 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
KPHECLMH_02084 3.13e-99 - - - L - - - Transposase DDE domain
KPHECLMH_02085 5.83e-182 - - - L - - - COG3547 Transposase and inactivated derivatives
KPHECLMH_02086 0.0 eriC - - P ko:K03281 - ko00000 chloride
KPHECLMH_02087 7.81e-247 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPHECLMH_02088 4.23e-184 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
KPHECLMH_02089 1.45e-218 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
KPHECLMH_02090 2.18e-185 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KPHECLMH_02091 3.55e-155 gpm5 - - G - - - Phosphoglycerate mutase family
KPHECLMH_02092 1.12e-130 - - - K - - - FR47-like protein
KPHECLMH_02093 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
KPHECLMH_02094 2.31e-278 yibE - - S - - - overlaps another CDS with the same product name
KPHECLMH_02095 1.53e-241 - - - - - - - -
KPHECLMH_02096 5.03e-180 - - - S - - - NADPH-dependent FMN reductase
KPHECLMH_02097 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_02098 9.54e-209 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KPHECLMH_02099 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KPHECLMH_02100 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
KPHECLMH_02101 9.05e-55 - - - - - - - -
KPHECLMH_02102 6.71e-284 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KPHECLMH_02103 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KPHECLMH_02104 3.95e-254 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KPHECLMH_02105 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KPHECLMH_02106 1.3e-134 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KPHECLMH_02107 1.44e-104 - - - K - - - Transcriptional regulator
KPHECLMH_02109 0.0 - - - C - - - FMN_bind
KPHECLMH_02110 1.37e-220 - - - K - - - Transcriptional regulator
KPHECLMH_02111 2.67e-124 - - - K - - - Helix-turn-helix domain
KPHECLMH_02112 2.49e-178 - - - K - - - sequence-specific DNA binding
KPHECLMH_02113 2.48e-63 - - - S - - - AAA domain
KPHECLMH_02114 9.7e-34 - - - S - - - AAA domain
KPHECLMH_02115 1.42e-08 - - - - - - - -
KPHECLMH_02116 9.1e-47 - - - M - - - MucBP domain
KPHECLMH_02117 0.0 - - - M - - - MucBP domain
KPHECLMH_02118 1.39e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
KPHECLMH_02119 5.62e-56 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
KPHECLMH_02120 4.61e-222 - - - L - - - Belongs to the 'phage' integrase family
KPHECLMH_02121 6.25e-83 - - - V - - - Type I restriction modification DNA specificity domain
KPHECLMH_02122 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KPHECLMH_02123 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KPHECLMH_02124 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KPHECLMH_02125 2.66e-132 - - - G - - - Glycogen debranching enzyme
KPHECLMH_02126 1.22e-210 yjdB - - S - - - Domain of unknown function (DUF4767)
KPHECLMH_02127 2.02e-192 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
KPHECLMH_02128 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
KPHECLMH_02129 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
KPHECLMH_02130 5.74e-32 - - - - - - - -
KPHECLMH_02131 1.37e-116 - - - - - - - -
KPHECLMH_02132 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
KPHECLMH_02133 0.0 XK27_09800 - - I - - - Acyltransferase family
KPHECLMH_02134 2.09e-60 - - - S - - - MORN repeat
KPHECLMH_02135 1.23e-266 - - - S - - - Cysteine-rich secretory protein family
KPHECLMH_02136 5.06e-297 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
KPHECLMH_02137 4.73e-206 - - - L ko:K07497 - ko00000 hmm pf00665
KPHECLMH_02138 2.13e-167 - - - L - - - Helix-turn-helix domain
KPHECLMH_02139 1.07e-74 - - - K - - - HxlR-like helix-turn-helix
KPHECLMH_02140 3.87e-141 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
KPHECLMH_02141 7.8e-58 - - - K - - - Helix-turn-helix domain
KPHECLMH_02142 1.26e-70 - - - - - - - -
KPHECLMH_02143 0.0 - - - L - - - DNA helicase
KPHECLMH_02144 1.38e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
KPHECLMH_02145 1.12e-241 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KPHECLMH_02146 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
KPHECLMH_02147 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_02148 9.68e-34 - - - - - - - -
KPHECLMH_02149 1.02e-98 - - - S - - - Domain of unknown function (DUF3284)
KPHECLMH_02150 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_02151 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02152 6.97e-209 - - - GK - - - ROK family
KPHECLMH_02153 1.14e-173 yecA - - K - - - Helix-turn-helix domain, rpiR family
KPHECLMH_02154 1.7e-243 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPHECLMH_02155 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KPHECLMH_02156 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KPHECLMH_02157 4.65e-229 - - - - - - - -
KPHECLMH_02158 8.73e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
KPHECLMH_02159 3.74e-204 yunF - - F - - - Protein of unknown function DUF72
KPHECLMH_02160 6.59e-92 - - - F - - - DNA mismatch repair protein MutT
KPHECLMH_02161 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPHECLMH_02163 8.6e-272 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
KPHECLMH_02164 1.29e-66 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KPHECLMH_02165 2.91e-54 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KPHECLMH_02167 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
KPHECLMH_02168 1.87e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPHECLMH_02169 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPHECLMH_02170 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
KPHECLMH_02171 6.21e-207 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KPHECLMH_02172 4.35e-118 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
KPHECLMH_02173 3.56e-84 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
KPHECLMH_02174 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KPHECLMH_02175 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
KPHECLMH_02176 5.67e-27 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
KPHECLMH_02177 2.95e-57 - - - S - - - ankyrin repeats
KPHECLMH_02178 5.3e-49 - - - - - - - -
KPHECLMH_02179 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KPHECLMH_02180 5.78e-292 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPHECLMH_02181 4.31e-191 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KPHECLMH_02182 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPHECLMH_02183 1.82e-232 - - - S - - - DUF218 domain
KPHECLMH_02184 2.04e-177 - - - - - - - -
KPHECLMH_02185 1.45e-191 yxeH - - S - - - hydrolase
KPHECLMH_02186 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
KPHECLMH_02187 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
KPHECLMH_02188 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
KPHECLMH_02189 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KPHECLMH_02190 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPHECLMH_02191 8.29e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPHECLMH_02192 2.37e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
KPHECLMH_02193 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
KPHECLMH_02194 2.31e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KPHECLMH_02195 6.59e-170 - - - S - - - YheO-like PAS domain
KPHECLMH_02196 4.01e-36 - - - - - - - -
KPHECLMH_02197 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPHECLMH_02198 3.62e-305 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KPHECLMH_02199 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KPHECLMH_02200 1.49e-273 - - - J - - - translation release factor activity
KPHECLMH_02201 2.58e-163 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
KPHECLMH_02202 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
KPHECLMH_02203 1.78e-191 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KPHECLMH_02204 1.51e-188 - - - - - - - -
KPHECLMH_02205 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPHECLMH_02206 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KPHECLMH_02207 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPHECLMH_02208 1.43e-274 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPHECLMH_02209 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KPHECLMH_02210 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KPHECLMH_02211 2.77e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_02212 7.44e-203 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_02213 3.35e-170 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KPHECLMH_02214 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KPHECLMH_02215 2.61e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KPHECLMH_02216 2.09e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KPHECLMH_02217 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KPHECLMH_02218 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KPHECLMH_02219 3.52e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
KPHECLMH_02220 2.52e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KPHECLMH_02221 1.3e-110 queT - - S - - - QueT transporter
KPHECLMH_02222 4.87e-148 - - - S - - - (CBS) domain
KPHECLMH_02223 0.0 - - - S - - - Putative peptidoglycan binding domain
KPHECLMH_02224 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KPHECLMH_02225 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPHECLMH_02226 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPHECLMH_02227 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KPHECLMH_02228 7.72e-57 yabO - - J - - - S4 domain protein
KPHECLMH_02230 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KPHECLMH_02231 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
KPHECLMH_02232 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPHECLMH_02233 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KPHECLMH_02234 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPHECLMH_02235 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPHECLMH_02236 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPHECLMH_02237 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KPHECLMH_02238 2.81e-36 - - - - - - - -
KPHECLMH_02239 0.0 - - - L - - - MobA MobL family protein
KPHECLMH_02240 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KPHECLMH_02241 1.74e-49 - - - K - - - LysR substrate binding domain
KPHECLMH_02242 1.92e-239 - - - C - - - FMN_bind
KPHECLMH_02243 2.43e-54 tnpR - - L - - - Resolvase, N terminal domain
KPHECLMH_02244 4.29e-220 - - - L - - - Transposase and inactivated derivatives, IS30 family
KPHECLMH_02245 0.0 ybeC - - E - - - amino acid
KPHECLMH_02246 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPHECLMH_02247 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KPHECLMH_02248 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
KPHECLMH_02249 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
KPHECLMH_02250 1.41e-241 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
KPHECLMH_02251 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KPHECLMH_02252 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
KPHECLMH_02253 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_02254 1.97e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
KPHECLMH_02255 5.13e-268 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
KPHECLMH_02256 7.03e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KPHECLMH_02257 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KPHECLMH_02258 8.85e-212 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPHECLMH_02259 9.89e-76 yabA - - L - - - Involved in initiation control of chromosome replication
KPHECLMH_02260 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KPHECLMH_02261 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
KPHECLMH_02262 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPHECLMH_02263 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
KPHECLMH_02264 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPHECLMH_02265 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPHECLMH_02266 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPHECLMH_02267 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPHECLMH_02268 2.73e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KPHECLMH_02269 5.92e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KPHECLMH_02270 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPHECLMH_02271 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPHECLMH_02272 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KPHECLMH_02273 1.26e-50 - - - K - - - Helix-turn-helix domain
KPHECLMH_02274 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPHECLMH_02275 3.93e-85 - - - L - - - nuclease
KPHECLMH_02276 3.38e-225 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
KPHECLMH_02277 3.22e-73 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPHECLMH_02278 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPHECLMH_02279 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPHECLMH_02280 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPHECLMH_02281 1.63e-201 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_02282 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KPHECLMH_02283 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KPHECLMH_02284 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KPHECLMH_02285 3.09e-128 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
KPHECLMH_02286 5.03e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
KPHECLMH_02287 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPHECLMH_02288 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPHECLMH_02289 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KPHECLMH_02290 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPHECLMH_02291 2e-264 yacL - - S - - - domain protein
KPHECLMH_02292 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPHECLMH_02293 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
KPHECLMH_02294 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
KPHECLMH_02295 3.82e-157 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPHECLMH_02296 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KPHECLMH_02297 3.36e-66 - - - L ko:K07487 - ko00000 Transposase
KPHECLMH_02299 5.64e-66 - - - L - - - Belongs to the 'phage' integrase family
KPHECLMH_02301 1.02e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KPHECLMH_02302 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KPHECLMH_02303 1.31e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KPHECLMH_02304 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
KPHECLMH_02305 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
KPHECLMH_02306 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KPHECLMH_02307 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KPHECLMH_02308 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPHECLMH_02309 6.62e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KPHECLMH_02310 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
KPHECLMH_02311 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPHECLMH_02312 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPHECLMH_02313 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KPHECLMH_02314 1.59e-247 ysdE - - P - - - Citrate transporter
KPHECLMH_02315 1.08e-212 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
KPHECLMH_02316 1.61e-70 - - - S - - - Cupin domain
KPHECLMH_02317 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
KPHECLMH_02321 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
KPHECLMH_02322 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
KPHECLMH_02325 6.19e-208 - - - K - - - Transcriptional regulator
KPHECLMH_02326 2.95e-207 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KPHECLMH_02327 1.66e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
KPHECLMH_02328 2.45e-101 - - - K - - - Winged helix DNA-binding domain
KPHECLMH_02329 0.0 ycaM - - E - - - amino acid
KPHECLMH_02330 2.38e-164 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
KPHECLMH_02331 4.3e-44 - - - - - - - -
KPHECLMH_02332 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
KPHECLMH_02333 0.0 - - - M - - - Domain of unknown function (DUF5011)
KPHECLMH_02334 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
KPHECLMH_02335 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
KPHECLMH_02336 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
KPHECLMH_02337 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KPHECLMH_02338 3.26e-203 - - - EG - - - EamA-like transporter family
KPHECLMH_02339 2.05e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPHECLMH_02340 5.06e-196 - - - S - - - hydrolase
KPHECLMH_02341 7.63e-107 - - - - - - - -
KPHECLMH_02342 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
KPHECLMH_02343 1.4e-181 epsV - - S - - - glycosyl transferase family 2
KPHECLMH_02344 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
KPHECLMH_02345 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPHECLMH_02346 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
KPHECLMH_02347 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02348 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02349 4.77e-316 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
KPHECLMH_02350 8.66e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KPHECLMH_02351 1.08e-248 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-type multidrug transport system, permease component
KPHECLMH_02352 9.69e-149 - - - K - - - Transcriptional regulator
KPHECLMH_02353 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPHECLMH_02354 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
KPHECLMH_02355 6.58e-262 - - - EGP - - - Transmembrane secretion effector
KPHECLMH_02356 3.64e-293 - - - S - - - Sterol carrier protein domain
KPHECLMH_02357 1.65e-267 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
KPHECLMH_02358 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
KPHECLMH_02359 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KPHECLMH_02360 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
KPHECLMH_02361 3.24e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
KPHECLMH_02362 1.03e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KPHECLMH_02363 4.72e-40 - - - S - - - Pentapeptide repeats (8 copies)
KPHECLMH_02364 7.71e-185 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPHECLMH_02365 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
KPHECLMH_02366 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KPHECLMH_02368 1.21e-69 - - - - - - - -
KPHECLMH_02369 4.34e-151 - - - - - - - -
KPHECLMH_02370 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
KPHECLMH_02371 8.32e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KPHECLMH_02372 4.79e-13 - - - - - - - -
KPHECLMH_02373 4.87e-66 - - - - - - - -
KPHECLMH_02374 1.76e-114 - - - - - - - -
KPHECLMH_02375 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
KPHECLMH_02376 1.08e-47 - - - - - - - -
KPHECLMH_02377 2.7e-104 usp5 - - T - - - universal stress protein
KPHECLMH_02378 1.12e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KPHECLMH_02379 1.32e-170 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KPHECLMH_02380 1.98e-155 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_02381 8.47e-273 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KPHECLMH_02382 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
KPHECLMH_02383 5.62e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KPHECLMH_02384 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
KPHECLMH_02385 1.17e-135 - - - K - - - transcriptional regulator
KPHECLMH_02386 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KPHECLMH_02387 1.49e-63 - - - - - - - -
KPHECLMH_02388 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
KPHECLMH_02389 4.5e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KPHECLMH_02390 2.87e-56 - - - - - - - -
KPHECLMH_02391 3.35e-75 - - - - - - - -
KPHECLMH_02392 4.62e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_02393 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
KPHECLMH_02394 2.42e-65 - - - - - - - -
KPHECLMH_02395 1.9e-165 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
KPHECLMH_02396 0.0 hpk2 - - T - - - Histidine kinase
KPHECLMH_02397 8.98e-86 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_02398 0.0 ydiC - - EGP - - - Major Facilitator
KPHECLMH_02399 1.55e-55 - - - - - - - -
KPHECLMH_02400 4.48e-52 - - - - - - - -
KPHECLMH_02401 1.15e-152 - - - - - - - -
KPHECLMH_02402 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KPHECLMH_02403 2.03e-153 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02404 4.24e-94 ywnA - - K - - - Transcriptional regulator
KPHECLMH_02405 1.1e-280 - - - - - - - -
KPHECLMH_02406 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KPHECLMH_02407 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KPHECLMH_02408 6.53e-58 - - - - - - - -
KPHECLMH_02409 4.63e-119 - - - K - - - Transcriptional regulator PadR-like family
KPHECLMH_02410 8.44e-119 - - - P - - - Major Facilitator Superfamily
KPHECLMH_02411 8.56e-193 - - - P - - - Major Facilitator Superfamily
KPHECLMH_02412 1.66e-305 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KPHECLMH_02413 7.39e-226 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KPHECLMH_02414 8.95e-60 - - - - - - - -
KPHECLMH_02415 8.61e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
KPHECLMH_02416 4.83e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KPHECLMH_02417 0.0 sufI - - Q - - - Multicopper oxidase
KPHECLMH_02418 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KPHECLMH_02419 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KPHECLMH_02420 1.96e-295 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KPHECLMH_02421 8.37e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
KPHECLMH_02422 2.16e-103 - - - - - - - -
KPHECLMH_02423 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPHECLMH_02424 2.12e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
KPHECLMH_02425 1.07e-208 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_02426 0.0 - - - - - - - -
KPHECLMH_02427 1.94e-100 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
KPHECLMH_02428 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KPHECLMH_02429 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_02430 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
KPHECLMH_02431 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPHECLMH_02432 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
KPHECLMH_02433 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPHECLMH_02434 4.56e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KPHECLMH_02435 2.24e-262 - - - EGP - - - Transporter, major facilitator family protein
KPHECLMH_02436 5.9e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KPHECLMH_02437 4.75e-212 - - - K - - - Transcriptional regulator
KPHECLMH_02438 8.38e-192 - - - S - - - hydrolase
KPHECLMH_02439 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KPHECLMH_02440 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPHECLMH_02444 3.65e-66 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPHECLMH_02445 1.15e-43 - - - - - - - -
KPHECLMH_02446 1.11e-84 - - - - - - - -
KPHECLMH_02447 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
KPHECLMH_02448 1.04e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPHECLMH_02449 8.38e-152 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
KPHECLMH_02450 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
KPHECLMH_02451 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KPHECLMH_02452 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
KPHECLMH_02453 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KPHECLMH_02454 1.66e-150 - - - S - - - Calcineurin-like phosphoesterase
KPHECLMH_02455 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KPHECLMH_02456 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPHECLMH_02457 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
KPHECLMH_02459 3.73e-112 - - - S - - - Prokaryotic N-terminal methylation motif
KPHECLMH_02460 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
KPHECLMH_02461 3e-105 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
KPHECLMH_02462 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
KPHECLMH_02463 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KPHECLMH_02464 1.8e-222 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
KPHECLMH_02465 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPHECLMH_02466 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
KPHECLMH_02467 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
KPHECLMH_02468 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
KPHECLMH_02469 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KPHECLMH_02470 8.96e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KPHECLMH_02471 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_02472 1.32e-92 - - - - - - - -
KPHECLMH_02473 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KPHECLMH_02474 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KPHECLMH_02475 2.74e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KPHECLMH_02476 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KPHECLMH_02477 7.94e-114 ykuL - - S - - - (CBS) domain
KPHECLMH_02478 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KPHECLMH_02479 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPHECLMH_02480 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KPHECLMH_02481 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
KPHECLMH_02482 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KPHECLMH_02483 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPHECLMH_02484 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KPHECLMH_02485 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
KPHECLMH_02486 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPHECLMH_02487 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
KPHECLMH_02488 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPHECLMH_02489 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KPHECLMH_02490 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
KPHECLMH_02491 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPHECLMH_02492 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KPHECLMH_02493 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KPHECLMH_02494 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KPHECLMH_02495 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPHECLMH_02496 1.64e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPHECLMH_02497 2.83e-114 - - - - - - - -
KPHECLMH_02498 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KPHECLMH_02499 1.3e-91 - - - - - - - -
KPHECLMH_02500 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KPHECLMH_02501 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPHECLMH_02502 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KPHECLMH_02503 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
KPHECLMH_02505 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KPHECLMH_02506 6.39e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KPHECLMH_02507 1.09e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPHECLMH_02508 6.85e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KPHECLMH_02509 1.75e-295 - - - M - - - O-Antigen ligase
KPHECLMH_02510 5.09e-165 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KPHECLMH_02511 5.71e-211 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_02512 2.25e-111 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_02513 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KPHECLMH_02514 2.27e-80 - - - P - - - Rhodanese Homology Domain
KPHECLMH_02515 6.11e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_02516 1.93e-266 - - - - - - - -
KPHECLMH_02517 4.8e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
KPHECLMH_02518 1.02e-230 - - - C - - - Zinc-binding dehydrogenase
KPHECLMH_02519 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
KPHECLMH_02520 1.27e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPHECLMH_02521 1.59e-160 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
KPHECLMH_02522 5.59e-102 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
KPHECLMH_02523 4.38e-102 - - - K - - - Transcriptional regulator
KPHECLMH_02524 3.73e-264 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KPHECLMH_02525 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KPHECLMH_02526 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KPHECLMH_02527 1.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KPHECLMH_02528 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
KPHECLMH_02529 6.34e-90 - - - S - - - Protein of unknown function (DUF1722)
KPHECLMH_02530 8.09e-146 - - - GM - - - epimerase
KPHECLMH_02531 0.0 - - - S - - - Zinc finger, swim domain protein
KPHECLMH_02532 1.76e-104 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02533 5.58e-274 - - - S - - - membrane
KPHECLMH_02534 2.15e-07 - - - K - - - transcriptional regulator
KPHECLMH_02535 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_02536 1.31e-29 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_02538 2.03e-84 - - - - - - - -
KPHECLMH_02539 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
KPHECLMH_02540 1.21e-73 - - - - - - - -
KPHECLMH_02541 1.24e-194 - - - K - - - Helix-turn-helix domain
KPHECLMH_02542 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPHECLMH_02543 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPHECLMH_02544 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_02545 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPHECLMH_02546 7.8e-238 - - - GM - - - Male sterility protein
KPHECLMH_02547 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_02548 2.18e-99 - - - M - - - LysM domain
KPHECLMH_02549 1.44e-128 - - - M - - - Lysin motif
KPHECLMH_02550 2.32e-137 - - - S - - - SdpI/YhfL protein family
KPHECLMH_02551 1.58e-72 nudA - - S - - - ASCH
KPHECLMH_02552 6.45e-209 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KPHECLMH_02553 8.76e-121 - - - - - - - -
KPHECLMH_02554 6.68e-156 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
KPHECLMH_02555 1.22e-272 - - - T - - - diguanylate cyclase
KPHECLMH_02556 3.55e-91 - - - S - - - Psort location Cytoplasmic, score
KPHECLMH_02557 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
KPHECLMH_02558 1.43e-57 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
KPHECLMH_02559 6.88e-151 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
KPHECLMH_02560 2.66e-38 - - - - - - - -
KPHECLMH_02561 1e-62 adhR - - K - - - helix_turn_helix, mercury resistance
KPHECLMH_02562 1.58e-47 - - - C - - - Flavodoxin
KPHECLMH_02563 8.31e-204 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
KPHECLMH_02564 7.51e-173 - - - C - - - Aldo/keto reductase family
KPHECLMH_02565 5.31e-102 - - - GM - - - NmrA-like family
KPHECLMH_02566 1.91e-44 - - - C - - - Flavodoxin
KPHECLMH_02567 3.99e-14 - - - L ko:K07487 - ko00000 Transposase
KPHECLMH_02568 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPHECLMH_02569 6.88e-152 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02570 8.16e-89 - - - NU - - - Mycoplasma protein of unknown function, DUF285
KPHECLMH_02571 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
KPHECLMH_02572 1.96e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KPHECLMH_02573 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KPHECLMH_02574 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPHECLMH_02575 4.81e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KPHECLMH_02576 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPHECLMH_02577 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPHECLMH_02578 0.0 ydaO - - E - - - amino acid
KPHECLMH_02579 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
KPHECLMH_02580 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KPHECLMH_02581 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KPHECLMH_02582 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
KPHECLMH_02583 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KPHECLMH_02584 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPHECLMH_02585 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPHECLMH_02586 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPHECLMH_02587 3.68e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
KPHECLMH_02588 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KPHECLMH_02589 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPHECLMH_02590 3.99e-200 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KPHECLMH_02591 1.83e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KPHECLMH_02592 2.91e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
KPHECLMH_02593 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPHECLMH_02594 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPHECLMH_02595 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KPHECLMH_02596 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
KPHECLMH_02597 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KPHECLMH_02598 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPHECLMH_02599 2.55e-212 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPHECLMH_02600 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KPHECLMH_02601 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KPHECLMH_02602 3.69e-159 - - - T - - - Putative diguanylate phosphodiesterase
KPHECLMH_02603 0.0 nox - - C - - - NADH oxidase
KPHECLMH_02604 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPHECLMH_02605 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
KPHECLMH_02606 2.07e-60 - - - S - - - Protein of unknown function (DUF3290)
KPHECLMH_02607 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KPHECLMH_02608 6.88e-169 - - - T - - - Putative diguanylate phosphodiesterase
KPHECLMH_02609 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KPHECLMH_02610 4.63e-135 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KPHECLMH_02611 4.19e-265 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
KPHECLMH_02612 3.17e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
KPHECLMH_02613 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPHECLMH_02614 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KPHECLMH_02615 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPHECLMH_02616 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KPHECLMH_02617 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KPHECLMH_02618 6.07e-114 - - - S - - - Short repeat of unknown function (DUF308)
KPHECLMH_02619 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KPHECLMH_02620 5.32e-242 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KPHECLMH_02621 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KPHECLMH_02622 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KPHECLMH_02623 5.18e-224 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPHECLMH_02624 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPHECLMH_02626 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
KPHECLMH_02627 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
KPHECLMH_02628 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPHECLMH_02629 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KPHECLMH_02630 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPHECLMH_02631 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPHECLMH_02632 4.68e-167 - - - - - - - -
KPHECLMH_02633 0.0 eriC - - P ko:K03281 - ko00000 chloride
KPHECLMH_02634 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KPHECLMH_02635 3.83e-179 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
KPHECLMH_02636 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KPHECLMH_02637 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KPHECLMH_02638 0.0 - - - M - - - Domain of unknown function (DUF5011)
KPHECLMH_02639 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_02640 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_02641 2.29e-136 - - - - - - - -
KPHECLMH_02642 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPHECLMH_02643 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPHECLMH_02644 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KPHECLMH_02645 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
KPHECLMH_02646 4.88e-112 - - - J - - - Acetyltransferase (GNAT) domain
KPHECLMH_02647 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KPHECLMH_02648 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KPHECLMH_02649 1.79e-212 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
KPHECLMH_02650 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KPHECLMH_02651 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
KPHECLMH_02652 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_02653 7.74e-154 - - - S - - - Protein of unknown function (DUF1361)
KPHECLMH_02654 2.39e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPHECLMH_02655 2.18e-182 ybbR - - S - - - YbbR-like protein
KPHECLMH_02656 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPHECLMH_02657 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPHECLMH_02658 5.44e-159 - - - T - - - EAL domain
KPHECLMH_02659 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
KPHECLMH_02660 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02661 1.46e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KPHECLMH_02662 3.38e-70 - - - - - - - -
KPHECLMH_02663 2.49e-95 - - - - - - - -
KPHECLMH_02664 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KPHECLMH_02665 3.51e-197 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
KPHECLMH_02666 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPHECLMH_02667 2.6e-185 - - - - - - - -
KPHECLMH_02669 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
KPHECLMH_02670 3.88e-46 - - - - - - - -
KPHECLMH_02671 1.41e-115 - - - V - - - VanZ like family
KPHECLMH_02672 1.69e-312 - - - EGP - - - Major Facilitator
KPHECLMH_02673 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KPHECLMH_02674 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KPHECLMH_02675 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KPHECLMH_02676 7.8e-196 licD - - M ko:K07271 - ko00000,ko01000 LicD family
KPHECLMH_02677 6.16e-107 - - - K - - - Transcriptional regulator
KPHECLMH_02678 1.36e-27 - - - - - - - -
KPHECLMH_02679 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KPHECLMH_02680 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_02681 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KPHECLMH_02682 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KPHECLMH_02683 1.83e-231 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KPHECLMH_02684 5.01e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPHECLMH_02685 0.0 oatA - - I - - - Acyltransferase
KPHECLMH_02686 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KPHECLMH_02687 7.76e-83 - - - O - - - OsmC-like protein
KPHECLMH_02688 3.8e-61 - - - - - - - -
KPHECLMH_02689 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
KPHECLMH_02690 6.12e-115 - - - - - - - -
KPHECLMH_02691 1.23e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KPHECLMH_02692 7.48e-96 - - - F - - - Nudix hydrolase
KPHECLMH_02693 1.48e-27 - - - - - - - -
KPHECLMH_02694 9.98e-134 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
KPHECLMH_02695 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KPHECLMH_02696 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
KPHECLMH_02697 1.01e-188 - - - - - - - -
KPHECLMH_02698 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
KPHECLMH_02699 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KPHECLMH_02700 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPHECLMH_02701 1.28e-54 - - - - - - - -
KPHECLMH_02703 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_02704 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KPHECLMH_02705 4.45e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_02706 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_02707 7.04e-108 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPHECLMH_02708 7.77e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KPHECLMH_02709 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KPHECLMH_02710 4.87e-180 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
KPHECLMH_02711 0.0 steT - - E ko:K03294 - ko00000 amino acid
KPHECLMH_02712 6.26e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_02713 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
KPHECLMH_02714 8.83e-93 - - - K - - - MarR family
KPHECLMH_02715 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
KPHECLMH_02716 1.19e-108 - - - S ko:K07090 - ko00000 membrane transporter protein
KPHECLMH_02717 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02718 9.85e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPHECLMH_02719 4.6e-102 rppH3 - - F - - - NUDIX domain
KPHECLMH_02720 2.27e-53 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
KPHECLMH_02721 4.42e-36 - - - - - - - -
KPHECLMH_02722 1.57e-164 pgm3 - - G - - - Phosphoglycerate mutase family
KPHECLMH_02723 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
KPHECLMH_02724 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
KPHECLMH_02725 1.19e-226 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KPHECLMH_02726 1.11e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KPHECLMH_02727 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KPHECLMH_02728 1.46e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
KPHECLMH_02729 3.69e-230 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KPHECLMH_02730 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KPHECLMH_02732 4.03e-170 spoVK - - O ko:K06413 - ko00000 ATPase family associated with various cellular activities (AAA)
KPHECLMH_02734 9.16e-61 - - - L - - - Helix-turn-helix domain
KPHECLMH_02735 1.51e-22 - - - L ko:K07497 - ko00000 hmm pf00665
KPHECLMH_02736 8.56e-38 - - - L ko:K07497 - ko00000 hmm pf00665
KPHECLMH_02737 6.67e-30 - - - L ko:K07497 - ko00000 hmm pf00665
KPHECLMH_02738 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPHECLMH_02740 7.66e-106 - - - - - - - -
KPHECLMH_02741 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
KPHECLMH_02742 7.27e-211 - - - I - - - Diacylglycerol kinase catalytic domain
KPHECLMH_02743 5.58e-87 - - - S - - - Protein of unknown function (DUF805)
KPHECLMH_02744 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
KPHECLMH_02745 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
KPHECLMH_02746 2.05e-55 - - - - - - - -
KPHECLMH_02748 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
KPHECLMH_02749 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KPHECLMH_02750 3.16e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
KPHECLMH_02751 3.79e-66 - - - L - - - Integrase
KPHECLMH_02752 1.53e-106 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
KPHECLMH_02753 9.13e-70 - - - S - - - Bacterial mobilisation protein (MobC)
KPHECLMH_02754 1.38e-231 - - - U - - - Relaxase/Mobilisation nuclease domain
KPHECLMH_02755 9.81e-73 repA - - S - - - Replication initiator protein A
KPHECLMH_02756 1.77e-56 - - - - - - - -
KPHECLMH_02757 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KPHECLMH_02758 1.45e-103 - - - L - - - Phage integrase family
KPHECLMH_02759 1.24e-39 - - - - - - - -
KPHECLMH_02760 5.12e-112 - - - - - - - -
KPHECLMH_02761 4.8e-74 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KPHECLMH_02762 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
KPHECLMH_02763 1.59e-76 - - - - - - - -
KPHECLMH_02764 7.79e-112 - - - K - - - MerR HTH family regulatory protein
KPHECLMH_02765 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
KPHECLMH_02766 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
KPHECLMH_02767 1.19e-169 - - - - - - - -
KPHECLMH_02768 1.75e-47 - - - K - - - MerR HTH family regulatory protein
KPHECLMH_02769 6.77e-154 azlC - - E - - - branched-chain amino acid
KPHECLMH_02770 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
KPHECLMH_02771 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KPHECLMH_02772 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
KPHECLMH_02773 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPHECLMH_02774 0.0 xylP2 - - G - - - symporter
KPHECLMH_02775 2.98e-246 - - - I - - - alpha/beta hydrolase fold
KPHECLMH_02776 2.74e-63 - - - - - - - -
KPHECLMH_02777 1.91e-272 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
KPHECLMH_02778 2.62e-89 - - - K - - - LysR substrate binding domain
KPHECLMH_02779 4.77e-161 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KPHECLMH_02780 2.98e-215 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KPHECLMH_02781 6.17e-61 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
KPHECLMH_02782 2.23e-101 - - - L - - - manually curated
KPHECLMH_02783 1.54e-51 - - - P - - - CorA-like Mg2+ transporter protein
KPHECLMH_02784 1.36e-145 - - - P - - - CorA-like Mg2+ transporter protein
KPHECLMH_02785 5.3e-49 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPHECLMH_02786 2.21e-84 - - - D - - - AAA domain
KPHECLMH_02787 8.83e-06 - - - - - - - -
KPHECLMH_02788 1.73e-216 - - - S - - - Polyphosphate kinase 2 (PPK2)
KPHECLMH_02789 2.57e-128 - - - C - - - Nitroreductase family
KPHECLMH_02790 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
KPHECLMH_02791 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPHECLMH_02792 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPHECLMH_02793 1.48e-201 ccpB - - K - - - lacI family
KPHECLMH_02794 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
KPHECLMH_02795 2.48e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KPHECLMH_02796 3e-251 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
KPHECLMH_02797 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
KPHECLMH_02798 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPHECLMH_02799 9.38e-139 pncA - - Q - - - Isochorismatase family
KPHECLMH_02800 2.66e-172 - - - - - - - -
KPHECLMH_02801 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_02802 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
KPHECLMH_02803 7.2e-61 - - - S - - - Enterocin A Immunity
KPHECLMH_02804 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KPHECLMH_02805 5.94e-49 - - - S - - - Bacterial protein of unknown function (DUF916)
KPHECLMH_02806 7.67e-167 - - - S - - - Bacterial protein of unknown function (DUF916)
KPHECLMH_02807 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_02808 2.51e-150 - - - NU - - - Mycoplasma protein of unknown function, DUF285
KPHECLMH_02809 1.85e-125 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KPHECLMH_02810 4.63e-143 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
KPHECLMH_02811 2.97e-234 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
KPHECLMH_02812 4.03e-239 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
KPHECLMH_02813 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_02814 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KPHECLMH_02815 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
KPHECLMH_02816 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KPHECLMH_02817 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
KPHECLMH_02818 2.34e-139 - - - M - - - domain protein
KPHECLMH_02819 5.43e-220 - - - M - - - domain protein
KPHECLMH_02820 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
KPHECLMH_02821 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
KPHECLMH_02822 1.45e-46 - - - - - - - -
KPHECLMH_02823 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPHECLMH_02824 4.54e-126 - - - J - - - glyoxalase III activity
KPHECLMH_02825 2.49e-190 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_02826 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
KPHECLMH_02827 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
KPHECLMH_02828 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KPHECLMH_02829 7.5e-283 ysaA - - V - - - RDD family
KPHECLMH_02830 3.2e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
KPHECLMH_02831 4.44e-273 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KPHECLMH_02832 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KPHECLMH_02833 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KPHECLMH_02834 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KPHECLMH_02835 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPHECLMH_02836 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KPHECLMH_02837 1.81e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KPHECLMH_02838 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KPHECLMH_02839 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
KPHECLMH_02840 5.72e-81 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPHECLMH_02841 3.52e-160 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPHECLMH_02842 4.99e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KPHECLMH_02843 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
KPHECLMH_02844 3.87e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
KPHECLMH_02845 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
KPHECLMH_02846 7.66e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_02847 7.03e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPHECLMH_02848 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_02849 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KPHECLMH_02850 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KPHECLMH_02851 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
KPHECLMH_02852 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
KPHECLMH_02853 4.37e-241 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPHECLMH_02854 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KPHECLMH_02855 9.2e-62 - - - - - - - -
KPHECLMH_02856 3.9e-105 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPHECLMH_02857 2.65e-139 - - - K ko:K06977 - ko00000 acetyltransferase
KPHECLMH_02858 0.0 - - - S - - - ABC transporter, ATP-binding protein
KPHECLMH_02880 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KPHECLMH_02881 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
KPHECLMH_02882 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KPHECLMH_02883 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KPHECLMH_02884 3.06e-262 coiA - - S ko:K06198 - ko00000 Competence protein
KPHECLMH_02885 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KPHECLMH_02886 2.24e-148 yjbH - - Q - - - Thioredoxin
KPHECLMH_02887 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KPHECLMH_02888 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPHECLMH_02889 6.31e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KPHECLMH_02890 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
KPHECLMH_02891 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KPHECLMH_02892 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KPHECLMH_02893 7.81e-263 XK27_05220 - - S - - - AI-2E family transporter
KPHECLMH_02896 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_02897 5.26e-96 - - - - - - - -
KPHECLMH_02898 9.58e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KPHECLMH_02899 1.56e-56 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02900 6.83e-99 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
KPHECLMH_02901 6.61e-77 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPHECLMH_02902 3.74e-125 - - - V - - - VanZ like family
KPHECLMH_02903 1.26e-247 - - - V - - - Beta-lactamase
KPHECLMH_02904 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
KPHECLMH_02905 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPHECLMH_02906 8.93e-71 - - - S - - - Pfam:DUF59
KPHECLMH_02907 6.07e-223 ydhF - - S - - - Aldo keto reductase
KPHECLMH_02908 2.42e-127 - - - FG - - - HIT domain
KPHECLMH_02909 6.97e-49 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
KPHECLMH_02910 4.29e-101 - - - - - - - -
KPHECLMH_02911 8.79e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KPHECLMH_02912 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
KPHECLMH_02913 0.0 cadA - - P - - - P-type ATPase
KPHECLMH_02915 2.32e-160 - - - S - - - YjbR
KPHECLMH_02916 2.51e-280 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
KPHECLMH_02917 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KPHECLMH_02918 2.04e-255 glmS2 - - M - - - SIS domain
KPHECLMH_02919 3.58e-36 - - - S - - - Belongs to the LOG family
KPHECLMH_02920 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KPHECLMH_02921 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KPHECLMH_02922 4.28e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KPHECLMH_02923 4.75e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
KPHECLMH_02924 6.47e-208 - - - GM - - - NmrA-like family
KPHECLMH_02925 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
KPHECLMH_02926 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
KPHECLMH_02927 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
KPHECLMH_02928 1.7e-70 - - - - - - - -
KPHECLMH_02929 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
KPHECLMH_02930 1.22e-81 - - - - - - - -
KPHECLMH_02931 1.36e-112 - - - - - - - -
KPHECLMH_02932 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KPHECLMH_02933 3.78e-73 - - - - - - - -
KPHECLMH_02934 4.79e-21 - - - - - - - -
KPHECLMH_02935 3.57e-150 - - - GM - - - NmrA-like family
KPHECLMH_02936 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
KPHECLMH_02937 3.84e-202 - - - EG - - - EamA-like transporter family
KPHECLMH_02938 2.66e-155 - - - S - - - membrane
KPHECLMH_02939 6e-144 - - - S - - - VIT family
KPHECLMH_02940 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KPHECLMH_02941 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KPHECLMH_02942 8.01e-97 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
KPHECLMH_02943 4.26e-54 - - - - - - - -
KPHECLMH_02944 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
KPHECLMH_02945 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
KPHECLMH_02946 7.21e-35 - - - - - - - -
KPHECLMH_02947 2.55e-65 - - - - - - - -
KPHECLMH_02948 2.51e-84 - - - S - - - Protein of unknown function (DUF1398)
KPHECLMH_02949 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
KPHECLMH_02950 7.22e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KPHECLMH_02951 1.21e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
KPHECLMH_02952 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
KPHECLMH_02953 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
KPHECLMH_02954 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
KPHECLMH_02955 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KPHECLMH_02956 2.3e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KPHECLMH_02957 1.36e-209 yvgN - - C - - - Aldo keto reductase
KPHECLMH_02958 2.57e-171 - - - S - - - Putative threonine/serine exporter
KPHECLMH_02959 1.7e-101 - - - S - - - Threonine/Serine exporter, ThrE
KPHECLMH_02960 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KPHECLMH_02961 5.94e-118 ymdB - - S - - - Macro domain protein
KPHECLMH_02962 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
KPHECLMH_02963 1.58e-66 - - - - - - - -
KPHECLMH_02964 1.39e-211 - - - S - - - Protein of unknown function (DUF1002)
KPHECLMH_02965 0.0 - - - - - - - -
KPHECLMH_02966 6.48e-244 - - - S - - - Bacterial protein of unknown function (DUF916)
KPHECLMH_02967 7.78e-171 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_02968 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
KPHECLMH_02969 5.33e-114 - - - K - - - Winged helix DNA-binding domain
KPHECLMH_02970 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_02971 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
KPHECLMH_02972 4.45e-38 - - - - - - - -
KPHECLMH_02973 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
KPHECLMH_02974 2.41e-97 - - - M - - - PFAM NLP P60 protein
KPHECLMH_02975 6.18e-71 - - - - - - - -
KPHECLMH_02976 5.77e-81 - - - - - - - -
KPHECLMH_02978 9.39e-84 - - - - - - - -
KPHECLMH_02980 1.12e-134 - - - K - - - transcriptional regulator
KPHECLMH_02981 1.14e-228 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
KPHECLMH_02982 1.98e-173 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KPHECLMH_02983 1.5e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
KPHECLMH_02984 1.98e-232 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KPHECLMH_02985 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
KPHECLMH_02986 2.03e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPHECLMH_02987 2.34e-72 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
KPHECLMH_02988 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
KPHECLMH_02989 1.01e-26 - - - - - - - -
KPHECLMH_02990 4.27e-126 dpsB - - P - - - Belongs to the Dps family
KPHECLMH_02991 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
KPHECLMH_02992 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
KPHECLMH_02993 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KPHECLMH_02994 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPHECLMH_02995 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KPHECLMH_02996 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
KPHECLMH_02997 1.51e-234 - - - S - - - Cell surface protein
KPHECLMH_02998 4.81e-157 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_02999 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
KPHECLMH_03000 7.83e-60 - - - - - - - -
KPHECLMH_03001 8.19e-134 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
KPHECLMH_03002 1.03e-65 - - - - - - - -
KPHECLMH_03003 9.34e-317 - - - S - - - Putative metallopeptidase domain
KPHECLMH_03004 3.31e-282 - - - S - - - associated with various cellular activities
KPHECLMH_03005 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPHECLMH_03006 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
KPHECLMH_03007 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KPHECLMH_03008 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
KPHECLMH_03009 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KPHECLMH_03010 2.81e-90 - - - S - - - Domain of unknown function (DUF3284)
KPHECLMH_03011 2.18e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPHECLMH_03012 1.13e-228 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
KPHECLMH_03013 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KPHECLMH_03014 5.02e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
KPHECLMH_03015 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KPHECLMH_03016 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
KPHECLMH_03017 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
KPHECLMH_03018 1.03e-138 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KPHECLMH_03019 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KPHECLMH_03020 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KPHECLMH_03021 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KPHECLMH_03022 1.47e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KPHECLMH_03023 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPHECLMH_03024 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
KPHECLMH_03025 1.64e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
KPHECLMH_03026 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KPHECLMH_03027 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KPHECLMH_03028 1.43e-251 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KPHECLMH_03029 1.06e-231 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KPHECLMH_03030 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
KPHECLMH_03031 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
KPHECLMH_03033 6.97e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
KPHECLMH_03034 5.61e-173 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KPHECLMH_03035 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KPHECLMH_03036 6.82e-99 - - - - - - - -
KPHECLMH_03037 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KPHECLMH_03038 5.67e-179 - - - - - - - -
KPHECLMH_03040 2.69e-182 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
KPHECLMH_03041 1.67e-54 - - - - - - - -
KPHECLMH_03042 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPHECLMH_03043 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KPHECLMH_03044 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
KPHECLMH_03045 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
KPHECLMH_03046 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
KPHECLMH_03047 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
KPHECLMH_03048 2.9e-178 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KPHECLMH_03049 1.75e-98 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
KPHECLMH_03050 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPHECLMH_03051 5.24e-193 larE - - S ko:K06864 - ko00000 NAD synthase
KPHECLMH_03052 7.11e-227 - - - C - - - Zinc-binding dehydrogenase
KPHECLMH_03053 6.51e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KPHECLMH_03054 1.18e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KPHECLMH_03055 1.48e-140 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KPHECLMH_03056 4.15e-261 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
KPHECLMH_03057 1.02e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
KPHECLMH_03058 0.0 - - - L - - - HIRAN domain
KPHECLMH_03059 5.04e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KPHECLMH_03060 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
KPHECLMH_03061 1.27e-159 - - - - - - - -
KPHECLMH_03062 5.08e-192 - - - I - - - Alpha/beta hydrolase family
KPHECLMH_03063 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KPHECLMH_03064 1.23e-199 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPHECLMH_03065 2.81e-64 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPHECLMH_03066 8.14e-126 - - - S - - - CRISPR-associated protein (Cas_Csn2)
KPHECLMH_03067 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KPHECLMH_03068 1.34e-183 - - - F - - - Phosphorylase superfamily
KPHECLMH_03069 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KPHECLMH_03070 1.72e-142 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KPHECLMH_03071 1.27e-98 - - - K - - - Transcriptional regulator
KPHECLMH_03072 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KPHECLMH_03073 5.51e-106 - - - S - - - Protein of unknown function (DUF3021)
KPHECLMH_03074 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KPHECLMH_03075 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPHECLMH_03076 4.06e-214 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
KPHECLMH_03078 1.78e-203 morA - - S - - - reductase
KPHECLMH_03079 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
KPHECLMH_03080 1.92e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
KPHECLMH_03081 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KPHECLMH_03082 4.29e-102 - - - - - - - -
KPHECLMH_03083 0.0 - - - - - - - -
KPHECLMH_03084 6.49e-268 - - - C - - - Oxidoreductase
KPHECLMH_03085 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
KPHECLMH_03086 2.76e-115 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_03087 5.72e-261 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPHECLMH_03088 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KPHECLMH_03090 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
KPHECLMH_03091 1.14e-69 - - - K - - - Transcriptional regulator PadR-like family
KPHECLMH_03092 6.08e-180 - - - - - - - -
KPHECLMH_03093 1.57e-191 - - - - - - - -
KPHECLMH_03094 3.37e-115 - - - - - - - -
KPHECLMH_03095 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
KPHECLMH_03096 6.03e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPHECLMH_03097 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
KPHECLMH_03098 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
KPHECLMH_03099 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
KPHECLMH_03100 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
KPHECLMH_03102 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
KPHECLMH_03103 9.56e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
KPHECLMH_03104 1.58e-238 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
KPHECLMH_03105 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
KPHECLMH_03106 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
KPHECLMH_03107 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPHECLMH_03108 6.24e-244 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KPHECLMH_03109 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
KPHECLMH_03110 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KPHECLMH_03111 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KPHECLMH_03112 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPHECLMH_03113 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KPHECLMH_03114 2.91e-190 malA - - S - - - maltodextrose utilization protein MalA
KPHECLMH_03115 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
KPHECLMH_03116 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPHECLMH_03117 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KPHECLMH_03118 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
KPHECLMH_03119 4.73e-55 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KPHECLMH_03120 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KPHECLMH_03121 1.49e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPHECLMH_03122 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
KPHECLMH_03123 1.14e-76 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KPHECLMH_03124 5.16e-09 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
KPHECLMH_03125 7.07e-106 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
KPHECLMH_03126 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPHECLMH_03127 1.26e-216 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
KPHECLMH_03128 3.29e-232 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
KPHECLMH_03129 6.35e-147 - - - L ko:K07497 - ko00000 hmm pf00665
KPHECLMH_03130 1.06e-138 - - - L - - - Resolvase, N terminal domain
KPHECLMH_03131 2.61e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)