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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HOIPEFHO_00001	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HOIPEFHO_00002	1.26e-247	-	-	-	V	-	-	-	Beta-lactamase
HOIPEFHO_00003	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HOIPEFHO_00004	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOIPEFHO_00005	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HOIPEFHO_00006	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HOIPEFHO_00007	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HOIPEFHO_00008	6.97e-49	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HOIPEFHO_00009	4.29e-101	-	-	-	-	-	-	-	-
HOIPEFHO_00010	8.79e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOIPEFHO_00011	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HOIPEFHO_00012	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HOIPEFHO_00014	2.32e-160	-	-	-	S	-	-	-	YjbR
HOIPEFHO_00015	2.51e-280	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HOIPEFHO_00016	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HOIPEFHO_00017	2.04e-255	glmS2	-	-	M	-	-	-	SIS domain
HOIPEFHO_00018	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
HOIPEFHO_00019	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HOIPEFHO_00020	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOIPEFHO_00021	4.28e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_00022	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HOIPEFHO_00023	6.47e-208	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_00024	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HOIPEFHO_00025	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HOIPEFHO_00026	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HOIPEFHO_00027	1.7e-70	-	-	-	-	-	-	-	-
HOIPEFHO_00028	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HOIPEFHO_00029	1.22e-81	-	-	-	-	-	-	-	-
HOIPEFHO_00030	1.36e-112	-	-	-	-	-	-	-	-
HOIPEFHO_00031	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HOIPEFHO_00032	3.78e-73	-	-	-	-	-	-	-	-
HOIPEFHO_00033	4.79e-21	-	-	-	-	-	-	-	-
HOIPEFHO_00034	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_00035	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HOIPEFHO_00036	3.84e-202	-	-	-	EG	-	-	-	EamA-like transporter family
HOIPEFHO_00037	2.66e-155	-	-	-	S	-	-	-	membrane
HOIPEFHO_00038	6e-144	-	-	-	S	-	-	-	VIT family
HOIPEFHO_00039	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HOIPEFHO_00040	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HOIPEFHO_00041	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HOIPEFHO_00042	4.26e-54	-	-	-	-	-	-	-	-
HOIPEFHO_00043	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HOIPEFHO_00044	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HOIPEFHO_00045	7.21e-35	-	-	-	-	-	-	-	-
HOIPEFHO_00046	2.55e-65	-	-	-	-	-	-	-	-
HOIPEFHO_00047	2.51e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HOIPEFHO_00048	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HOIPEFHO_00049	7.22e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HOIPEFHO_00050	1.21e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HOIPEFHO_00051	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HOIPEFHO_00052	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HOIPEFHO_00053	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HOIPEFHO_00054	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HOIPEFHO_00055	2.3e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOIPEFHO_00056	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HOIPEFHO_00057	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOIPEFHO_00058	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HOIPEFHO_00059	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOIPEFHO_00060	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HOIPEFHO_00061	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HOIPEFHO_00062	1.58e-66	-	-	-	-	-	-	-	-
HOIPEFHO_00063	1.39e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HOIPEFHO_00064	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_00065	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HOIPEFHO_00066	7.78e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_00067	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HOIPEFHO_00068	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HOIPEFHO_00069	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_00070	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HOIPEFHO_00071	4.45e-38	-	-	-	-	-	-	-	-
HOIPEFHO_00072	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HOIPEFHO_00073	2.41e-97	-	-	-	M	-	-	-	PFAM NLP P60 protein
HOIPEFHO_00074	6.18e-71	-	-	-	-	-	-	-	-
HOIPEFHO_00075	5.77e-81	-	-	-	-	-	-	-	-
HOIPEFHO_00077	9.39e-84	-	-	-	-	-	-	-	-
HOIPEFHO_00079	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HOIPEFHO_00080	1.14e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HOIPEFHO_00081	1.98e-173	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HOIPEFHO_00082	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HOIPEFHO_00083	1.98e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOIPEFHO_00084	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HOIPEFHO_00085	2.03e-176	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOIPEFHO_00086	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HOIPEFHO_00087	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HOIPEFHO_00088	1.01e-26	-	-	-	-	-	-	-	-
HOIPEFHO_00089	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HOIPEFHO_00090	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HOIPEFHO_00091	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HOIPEFHO_00092	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HOIPEFHO_00093	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOIPEFHO_00094	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HOIPEFHO_00095	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HOIPEFHO_00096	1.51e-234	-	-	-	S	-	-	-	Cell surface protein
HOIPEFHO_00097	4.81e-157	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_00098	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_00099	7.83e-60	-	-	-	-	-	-	-	-
HOIPEFHO_00100	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HOIPEFHO_00101	1.03e-65	-	-	-	-	-	-	-	-
HOIPEFHO_00102	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HOIPEFHO_00103	3.31e-282	-	-	-	S	-	-	-	associated with various cellular activities
HOIPEFHO_00104	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOIPEFHO_00105	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HOIPEFHO_00106	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOIPEFHO_00107	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HOIPEFHO_00108	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOIPEFHO_00109	2.81e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HOIPEFHO_00110	2.18e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_00111	1.13e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HOIPEFHO_00112	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HOIPEFHO_00113	5.02e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HOIPEFHO_00114	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HOIPEFHO_00115	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HOIPEFHO_00116	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOIPEFHO_00117	1.03e-138	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HOIPEFHO_00118	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HOIPEFHO_00119	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HOIPEFHO_00120	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HOIPEFHO_00121	1.47e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOIPEFHO_00122	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HOIPEFHO_00123	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HOIPEFHO_00124	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HOIPEFHO_00125	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOIPEFHO_00126	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HOIPEFHO_00127	1.43e-251	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HOIPEFHO_00128	1.06e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HOIPEFHO_00129	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HOIPEFHO_00130	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HOIPEFHO_00131	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOIPEFHO_00132	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOIPEFHO_00133	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HOIPEFHO_00134	1.12e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOIPEFHO_00135	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HOIPEFHO_00136	3.3e-281	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOIPEFHO_00137	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOIPEFHO_00138	1.64e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOIPEFHO_00139	6.69e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HOIPEFHO_00140	4.57e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HOIPEFHO_00141	5.77e-214	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HOIPEFHO_00142	3.06e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOIPEFHO_00143	4.93e-82	-	-	-	-	-	-	-	-
HOIPEFHO_00144	2.16e-199	estA	-	-	S	-	-	-	Putative esterase
HOIPEFHO_00145	7.74e-174	-	-	-	K	-	-	-	UTRA domain
HOIPEFHO_00146	1.87e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_00147	5.07e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HOIPEFHO_00148	2.4e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HOIPEFHO_00149	5.33e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HOIPEFHO_00150	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_00151	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOIPEFHO_00152	4.34e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HOIPEFHO_00153	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_00154	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_00155	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOIPEFHO_00156	8.55e-116	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HOIPEFHO_00157	2.89e-73	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HOIPEFHO_00158	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HOIPEFHO_00159	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOIPEFHO_00160	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HOIPEFHO_00161	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HOIPEFHO_00163	1.91e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOIPEFHO_00164	1.74e-184	yxeH	-	-	S	-	-	-	hydrolase
HOIPEFHO_00165	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOIPEFHO_00166	1.02e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOIPEFHO_00167	1.66e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HOIPEFHO_00168	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HOIPEFHO_00169	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOIPEFHO_00170	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOIPEFHO_00171	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HOIPEFHO_00172	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HOIPEFHO_00173	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HOIPEFHO_00174	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOIPEFHO_00175	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOIPEFHO_00176	2.13e-145	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HOIPEFHO_00177	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HOIPEFHO_00179	1.31e-29	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_00180	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_00181	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HOIPEFHO_00182	5.58e-274	-	-	-	S	-	-	-	membrane
HOIPEFHO_00183	1.76e-104	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_00184	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HOIPEFHO_00185	8.09e-146	-	-	-	GM	-	-	-	epimerase
HOIPEFHO_00186	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HOIPEFHO_00187	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HOIPEFHO_00188	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HOIPEFHO_00189	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HOIPEFHO_00190	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HOIPEFHO_00191	3.73e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HOIPEFHO_00192	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00193	5.59e-102	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HOIPEFHO_00194	1.59e-160	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HOIPEFHO_00195	1.27e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOIPEFHO_00196	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HOIPEFHO_00197	1.02e-230	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HOIPEFHO_00198	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HOIPEFHO_00199	1.93e-266	-	-	-	-	-	-	-	-
HOIPEFHO_00200	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_00201	2.27e-80	-	-	-	P	-	-	-	Rhodanese Homology Domain
HOIPEFHO_00202	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HOIPEFHO_00203	2.25e-111	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_00204	5.71e-211	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_00205	5.09e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HOIPEFHO_00206	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HOIPEFHO_00207	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HOIPEFHO_00208	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOIPEFHO_00209	6.39e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HOIPEFHO_00210	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOIPEFHO_00212	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HOIPEFHO_00213	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HOIPEFHO_00214	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOIPEFHO_00215	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HOIPEFHO_00216	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HOIPEFHO_00217	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HOIPEFHO_00218	1.27e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HOIPEFHO_00219	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIPEFHO_00220	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOIPEFHO_00221	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOIPEFHO_00222	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOIPEFHO_00223	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOIPEFHO_00224	1.16e-243	-	-	-	S	-	-	-	Helix-turn-helix domain
HOIPEFHO_00225	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HOIPEFHO_00226	9.99e-39	-	-	-	M	-	-	-	Lysin motif
HOIPEFHO_00227	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HOIPEFHO_00228	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HOIPEFHO_00229	6.87e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HOIPEFHO_00230	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOIPEFHO_00231	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HOIPEFHO_00232	1.06e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HOIPEFHO_00233	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOIPEFHO_00234	1.27e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOIPEFHO_00235	6.46e-109	-	-	-	-	-	-	-	-
HOIPEFHO_00236	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00237	1.92e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOIPEFHO_00238	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOIPEFHO_00239	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HOIPEFHO_00240	5.66e-207	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HOIPEFHO_00241	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HOIPEFHO_00242	1.55e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HOIPEFHO_00243	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HOIPEFHO_00244	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_00245	1.74e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HOIPEFHO_00246	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HOIPEFHO_00247	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HOIPEFHO_00248	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HOIPEFHO_00249	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HOIPEFHO_00251	3.74e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOIPEFHO_00252	4.11e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOIPEFHO_00253	7.78e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HOIPEFHO_00254	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOIPEFHO_00255	1.89e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HOIPEFHO_00256	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HOIPEFHO_00257	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HOIPEFHO_00258	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HOIPEFHO_00259	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HOIPEFHO_00260	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOIPEFHO_00261	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOIPEFHO_00262	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOIPEFHO_00263	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00264	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HOIPEFHO_00265	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HOIPEFHO_00266	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOIPEFHO_00267	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HOIPEFHO_00268	4.19e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HOIPEFHO_00269	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOIPEFHO_00270	1.68e-310	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HOIPEFHO_00271	3.22e-87	-	-	-	-	-	-	-	-
HOIPEFHO_00272	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HOIPEFHO_00273	4.26e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_00274	4.69e-40	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOIPEFHO_00275	5.9e-57	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOIPEFHO_00276	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIPEFHO_00277	2.09e-270	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIPEFHO_00278	2.65e-246	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HOIPEFHO_00279	1.62e-161	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HOIPEFHO_00280	1.12e-288	-	-	-	-	-	-	-	-
HOIPEFHO_00281	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HOIPEFHO_00282	7.79e-78	-	-	-	-	-	-	-	-
HOIPEFHO_00283	2.79e-181	-	-	-	-	-	-	-	-
HOIPEFHO_00284	5.02e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOIPEFHO_00285	1.74e-175	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HOIPEFHO_00286	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HOIPEFHO_00287	2.21e-66	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HOIPEFHO_00289	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOIPEFHO_00290	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HOIPEFHO_00291	2.37e-65	-	-	-	-	-	-	-	-
HOIPEFHO_00292	1.18e-32	-	-	-	-	-	-	-	-
HOIPEFHO_00293	4.81e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HOIPEFHO_00294	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HOIPEFHO_00295	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HOIPEFHO_00296	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00297	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HOIPEFHO_00298	7.53e-142	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOIPEFHO_00299	4.87e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00300	5.37e-117	-	-	-	F	-	-	-	NUDIX domain
HOIPEFHO_00302	3.42e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HOIPEFHO_00303	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HOIPEFHO_00304	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HOIPEFHO_00311	1.91e-27	-	-	-	-	-	-	-	-
HOIPEFHO_00312	2.71e-91	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2321)
HOIPEFHO_00313	1.03e-11	-	-	-	-	-	-	-	-
HOIPEFHO_00321	6.79e-55	-	-	-	S	-	-	-	Siphovirus Gp157
HOIPEFHO_00322	1.22e-195	-	-	-	S	-	-	-	helicase activity
HOIPEFHO_00323	9.97e-94	-	-	-	L	-	-	-	AAA domain
HOIPEFHO_00324	1.6e-28	-	-	-	-	-	-	-	-
HOIPEFHO_00325	5.45e-96	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HOIPEFHO_00326	2.59e-165	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HOIPEFHO_00327	1.13e-47	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HOIPEFHO_00333	1.09e-74	-	-	-	-	-	-	-	-
HOIPEFHO_00335	3.33e-43	-	-	-	-	-	-	-	-
HOIPEFHO_00336	3.33e-170	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
HOIPEFHO_00337	1.06e-215	-	-	-	-	-	-	-	-
HOIPEFHO_00341	3.41e-13	-	-	-	-	-	-	-	-
HOIPEFHO_00342	3.35e-213	-	-	-	S	-	-	-	Terminase
HOIPEFHO_00343	1.47e-126	-	-	-	S	-	-	-	Phage portal protein
HOIPEFHO_00344	2.45e-72	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
HOIPEFHO_00345	5.26e-134	-	-	-	S	-	-	-	Phage capsid family
HOIPEFHO_00346	3.26e-19	-	-	-	-	-	-	-	-
HOIPEFHO_00347	3.04e-32	-	-	-	-	-	-	-	-
HOIPEFHO_00348	1.12e-32	-	-	-	-	-	-	-	-
HOIPEFHO_00349	1.3e-28	-	-	-	-	-	-	-	-
HOIPEFHO_00350	7.59e-44	-	-	-	S	-	-	-	Phage tail tube protein
HOIPEFHO_00353	1.5e-193	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HOIPEFHO_00355	4.6e-168	-	-	-	LM	-	-	-	DNA recombination
HOIPEFHO_00356	7.54e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HOIPEFHO_00358	2.88e-62	-	-	-	-	-	-	-	-
HOIPEFHO_00360	2.52e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HOIPEFHO_00361	1.05e-97	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOIPEFHO_00362	2.27e-197	-	-	-	G	-	-	-	Peptidase_C39 like family
HOIPEFHO_00363	2.63e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOIPEFHO_00364	2.43e-174	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HOIPEFHO_00365	8.89e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HOIPEFHO_00366	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HOIPEFHO_00367	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HOIPEFHO_00368	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HOIPEFHO_00369	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOIPEFHO_00370	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOIPEFHO_00371	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HOIPEFHO_00372	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HOIPEFHO_00373	3.66e-184	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOIPEFHO_00374	5e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HOIPEFHO_00375	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOIPEFHO_00376	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HOIPEFHO_00377	8.57e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HOIPEFHO_00378	7.78e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOIPEFHO_00379	7.87e-158	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HOIPEFHO_00380	3.36e-66	-	-	-	L	ko:K07487	-	ko00000	Transposase
HOIPEFHO_00381	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HOIPEFHO_00382	3.82e-157	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOIPEFHO_00383	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HOIPEFHO_00384	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HOIPEFHO_00385	6.97e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HOIPEFHO_00386	5.61e-173	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HOIPEFHO_00387	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HOIPEFHO_00388	6.82e-99	-	-	-	-	-	-	-	-
HOIPEFHO_00389	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HOIPEFHO_00390	5.67e-179	-	-	-	-	-	-	-	-
HOIPEFHO_00392	2.69e-182	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HOIPEFHO_00393	1.67e-54	-	-	-	-	-	-	-	-
HOIPEFHO_00394	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_00395	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HOIPEFHO_00396	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HOIPEFHO_00397	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HOIPEFHO_00398	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HOIPEFHO_00399	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HOIPEFHO_00400	2.9e-178	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HOIPEFHO_00401	1.75e-98	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HOIPEFHO_00402	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOIPEFHO_00403	5.24e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HOIPEFHO_00404	7.11e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HOIPEFHO_00405	6.51e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOIPEFHO_00406	1.18e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HOIPEFHO_00407	1.48e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOIPEFHO_00408	4.15e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HOIPEFHO_00409	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HOIPEFHO_00410	0.0	-	-	-	L	-	-	-	HIRAN domain
HOIPEFHO_00411	5.04e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HOIPEFHO_00412	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HOIPEFHO_00413	1.27e-159	-	-	-	-	-	-	-	-
HOIPEFHO_00414	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HOIPEFHO_00415	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HOIPEFHO_00416	1.23e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOIPEFHO_00417	2.81e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOIPEFHO_00418	8.14e-126	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HOIPEFHO_00419	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOIPEFHO_00420	1.34e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HOIPEFHO_00421	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HOIPEFHO_00422	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HOIPEFHO_00423	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00424	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HOIPEFHO_00425	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HOIPEFHO_00426	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HOIPEFHO_00427	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_00428	4.06e-214	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HOIPEFHO_00430	1.78e-203	morA	-	-	S	-	-	-	reductase
HOIPEFHO_00431	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HOIPEFHO_00432	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HOIPEFHO_00433	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HOIPEFHO_00434	4.29e-102	-	-	-	-	-	-	-	-
HOIPEFHO_00435	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_00436	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HOIPEFHO_00437	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HOIPEFHO_00438	2.76e-115	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00439	5.72e-261	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00440	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HOIPEFHO_00442	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HOIPEFHO_00443	1.14e-69	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HOIPEFHO_00444	6.08e-180	-	-	-	-	-	-	-	-
HOIPEFHO_00445	1.57e-191	-	-	-	-	-	-	-	-
HOIPEFHO_00446	3.37e-115	-	-	-	-	-	-	-	-
HOIPEFHO_00447	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HOIPEFHO_00448	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_00449	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HOIPEFHO_00450	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HOIPEFHO_00451	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HOIPEFHO_00452	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HOIPEFHO_00454	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_00455	9.56e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HOIPEFHO_00456	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HOIPEFHO_00457	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HOIPEFHO_00458	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HOIPEFHO_00459	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOIPEFHO_00460	6.24e-244	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOIPEFHO_00461	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HOIPEFHO_00462	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HOIPEFHO_00463	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOIPEFHO_00464	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_00465	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_00466	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HOIPEFHO_00467	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HOIPEFHO_00468	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOIPEFHO_00469	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HOIPEFHO_00470	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HOIPEFHO_00471	1.33e-77	-	-	-	-	-	-	-	-
HOIPEFHO_00472	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HOIPEFHO_00473	2.1e-41	-	-	-	-	-	-	-	-
HOIPEFHO_00474	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HOIPEFHO_00475	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HOIPEFHO_00476	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HOIPEFHO_00477	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HOIPEFHO_00478	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HOIPEFHO_00479	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOIPEFHO_00480	5.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOIPEFHO_00481	7.28e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOIPEFHO_00482	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOIPEFHO_00483	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOIPEFHO_00484	4.12e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HOIPEFHO_00485	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HOIPEFHO_00486	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOIPEFHO_00487	1.27e-75	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOIPEFHO_00488	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOIPEFHO_00489	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOIPEFHO_00490	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOIPEFHO_00491	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOIPEFHO_00492	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HOIPEFHO_00493	2.4e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOIPEFHO_00494	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOIPEFHO_00495	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HOIPEFHO_00496	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HOIPEFHO_00497	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HOIPEFHO_00498	5.05e-279	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HOIPEFHO_00499	3.09e-62	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HOIPEFHO_00500	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOIPEFHO_00501	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_00502	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOIPEFHO_00503	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HOIPEFHO_00504	1.88e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HOIPEFHO_00505	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HOIPEFHO_00506	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HOIPEFHO_00507	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HOIPEFHO_00508	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOIPEFHO_00509	3.3e-260	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HOIPEFHO_00510	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HOIPEFHO_00511	1.34e-52	-	-	-	-	-	-	-	-
HOIPEFHO_00512	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HOIPEFHO_00513	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HOIPEFHO_00514	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_00515	2.6e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HOIPEFHO_00516	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HOIPEFHO_00517	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HOIPEFHO_00518	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOIPEFHO_00519	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HOIPEFHO_00520	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HOIPEFHO_00521	4.29e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HOIPEFHO_00522	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOIPEFHO_00523	7.78e-300	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HOIPEFHO_00524	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOIPEFHO_00525	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOIPEFHO_00526	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HOIPEFHO_00527	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HOIPEFHO_00528	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HOIPEFHO_00529	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HOIPEFHO_00530	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HOIPEFHO_00531	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HOIPEFHO_00532	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HOIPEFHO_00533	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HOIPEFHO_00534	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00535	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HOIPEFHO_00536	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HOIPEFHO_00537	5.88e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HOIPEFHO_00538	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HOIPEFHO_00539	4.71e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HOIPEFHO_00540	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOIPEFHO_00541	1.56e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HOIPEFHO_00542	9.9e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOIPEFHO_00543	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HOIPEFHO_00544	1.77e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HOIPEFHO_00545	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOIPEFHO_00546	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOIPEFHO_00547	1.54e-146	-	-	-	L	ko:K07487	-	ko00000	Transposase
HOIPEFHO_00548	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HOIPEFHO_00549	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00550	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HOIPEFHO_00551	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HOIPEFHO_00552	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HOIPEFHO_00553	7.03e-62	-	-	-	-	-	-	-	-
HOIPEFHO_00554	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HOIPEFHO_00555	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HOIPEFHO_00556	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOIPEFHO_00557	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HOIPEFHO_00558	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HOIPEFHO_00559	1.35e-42	-	-	-	-	-	-	-	-
HOIPEFHO_00561	8.54e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HOIPEFHO_00562	1.61e-195	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HOIPEFHO_00563	7.65e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HOIPEFHO_00564	5.21e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HOIPEFHO_00565	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_00566	3.84e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HOIPEFHO_00567	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HOIPEFHO_00568	7.34e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_00569	9.55e-243	-	-	-	S	-	-	-	Cell surface protein
HOIPEFHO_00570	4.71e-81	-	-	-	-	-	-	-	-
HOIPEFHO_00571	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_00572	5.98e-217	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_00573	1.01e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HOIPEFHO_00574	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOIPEFHO_00575	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HOIPEFHO_00576	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HOIPEFHO_00577	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOIPEFHO_00578	1.53e-46	ccpB	-	-	K	-	-	-	lacI family
HOIPEFHO_00579	2.47e-126	ccpB	-	-	K	-	-	-	lacI family
HOIPEFHO_00580	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HOIPEFHO_00581	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HOIPEFHO_00582	4.02e-116	-	-	-	-	-	-	-	-
HOIPEFHO_00583	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HOIPEFHO_00584	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HOIPEFHO_00585	1.85e-51	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HOIPEFHO_00586	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HOIPEFHO_00587	2.27e-189	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HOIPEFHO_00588	1.44e-164	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HOIPEFHO_00590	9.65e-172	yicL	-	-	EG	-	-	-	EamA-like transporter family
HOIPEFHO_00591	3.41e-190	-	-	-	-	-	-	-	-
HOIPEFHO_00592	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00593	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HOIPEFHO_00594	1.37e-55	-	-	-	-	-	-	-	-
HOIPEFHO_00595	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HOIPEFHO_00596	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00597	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HOIPEFHO_00598	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_00599	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HOIPEFHO_00600	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOIPEFHO_00601	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HOIPEFHO_00602	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOIPEFHO_00603	2.26e-304	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HOIPEFHO_00604	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOIPEFHO_00605	1.66e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOIPEFHO_00606	9.7e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HOIPEFHO_00607	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOIPEFHO_00608	1.63e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOIPEFHO_00609	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOIPEFHO_00610	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOIPEFHO_00611	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HOIPEFHO_00612	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOIPEFHO_00613	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HOIPEFHO_00614	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HOIPEFHO_00615	4.17e-163	-	-	-	E	-	-	-	Methionine synthase
HOIPEFHO_00616	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HOIPEFHO_00617	2.62e-121	-	-	-	-	-	-	-	-
HOIPEFHO_00618	8.43e-198	-	-	-	T	-	-	-	EAL domain
HOIPEFHO_00619	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_00620	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HOIPEFHO_00621	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HOIPEFHO_00622	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HOIPEFHO_00623	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOIPEFHO_00624	4.08e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HOIPEFHO_00625	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOIPEFHO_00626	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HOIPEFHO_00627	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOIPEFHO_00628	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOIPEFHO_00629	1.27e-160	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HOIPEFHO_00630	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOIPEFHO_00631	1.12e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HOIPEFHO_00632	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HOIPEFHO_00633	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HOIPEFHO_00634	8.98e-30	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HOIPEFHO_00635	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HOIPEFHO_00636	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HOIPEFHO_00637	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOIPEFHO_00638	3.59e-26	-	-	-	-	-	-	-	-
HOIPEFHO_00639	1.21e-183	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOIPEFHO_00640	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOIPEFHO_00641	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HOIPEFHO_00642	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOIPEFHO_00643	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HOIPEFHO_00644	1.27e-219	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HOIPEFHO_00645	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_00646	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_00647	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOIPEFHO_00648	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HOIPEFHO_00649	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HOIPEFHO_00650	2.97e-76	-	-	-	-	-	-	-	-
HOIPEFHO_00651	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HOIPEFHO_00652	1.55e-79	-	-	-	-	-	-	-	-
HOIPEFHO_00653	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HOIPEFHO_00654	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HOIPEFHO_00655	5.66e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOIPEFHO_00656	1.74e-178	-	-	-	-	-	-	-	-
HOIPEFHO_00657	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOIPEFHO_00658	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00659	4.74e-208	-	-	-	S	-	-	-	Putative esterase
HOIPEFHO_00660	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HOIPEFHO_00661	5.31e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HOIPEFHO_00662	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HOIPEFHO_00663	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HOIPEFHO_00664	2.12e-98	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HOIPEFHO_00665	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HOIPEFHO_00666	3.77e-24	-	-	-	-	-	-	-	-
HOIPEFHO_00667	5.88e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HOIPEFHO_00668	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HOIPEFHO_00669	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HOIPEFHO_00670	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOIPEFHO_00671	4.28e-184	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HOIPEFHO_00672	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HOIPEFHO_00673	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HOIPEFHO_00674	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HOIPEFHO_00675	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HOIPEFHO_00676	4.15e-78	-	-	-	-	-	-	-	-
HOIPEFHO_00677	1.65e-97	-	-	-	-	-	-	-	-
HOIPEFHO_00678	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HOIPEFHO_00679	1.57e-71	-	-	-	-	-	-	-	-
HOIPEFHO_00680	6.46e-61	-	-	-	-	-	-	-	-
HOIPEFHO_00681	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HOIPEFHO_00682	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HOIPEFHO_00683	4.85e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HOIPEFHO_00684	9.66e-88	-	-	-	-	-	-	-	-
HOIPEFHO_00685	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_00686	4.83e-64	-	-	-	-	-	-	-	-
HOIPEFHO_00687	1.75e-75	-	-	-	-	-	-	-	-
HOIPEFHO_00689	1.86e-210	-	-	-	-	-	-	-	-
HOIPEFHO_00690	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00691	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HOIPEFHO_00692	2.67e-222	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HOIPEFHO_00693	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HOIPEFHO_00694	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HOIPEFHO_00695	1.49e-41	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOIPEFHO_00696	6.57e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HOIPEFHO_00697	2.02e-39	-	-	-	-	-	-	-	-
HOIPEFHO_00698	1.48e-71	-	-	-	-	-	-	-	-
HOIPEFHO_00699	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HOIPEFHO_00700	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_00701	1.22e-120	-	-	-	K	-	-	-	transcriptional regulator
HOIPEFHO_00702	1.54e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOIPEFHO_00703	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HOIPEFHO_00704	5.3e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_00705	7.34e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HOIPEFHO_00706	2.9e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HOIPEFHO_00707	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HOIPEFHO_00708	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HOIPEFHO_00709	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOIPEFHO_00710	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HOIPEFHO_00711	8.45e-92	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HOIPEFHO_00712	4.31e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOIPEFHO_00713	1.08e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOIPEFHO_00714	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HOIPEFHO_00715	2.85e-214	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HOIPEFHO_00716	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOIPEFHO_00717	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOIPEFHO_00718	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOIPEFHO_00719	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00720	1.13e-184	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_00721	3.34e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HOIPEFHO_00722	2.16e-162	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HOIPEFHO_00723	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HOIPEFHO_00724	2.87e-186	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HOIPEFHO_00725	7.13e-75	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HOIPEFHO_00726	1.87e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HOIPEFHO_00727	3.38e-225	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HOIPEFHO_00728	2.64e-47	entB	-	-	Q	-	-	-	Isochorismatase family
HOIPEFHO_00729	2.79e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOIPEFHO_00730	3.77e-289	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOIPEFHO_00731	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HOIPEFHO_00732	5.93e-166	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HOIPEFHO_00733	5.77e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOIPEFHO_00734	9.44e-134	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HOIPEFHO_00735	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HOIPEFHO_00737	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HOIPEFHO_00738	5.4e-175	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HOIPEFHO_00739	1.43e-178	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HOIPEFHO_00740	1.05e-48	-	-	-	GK	-	-	-	ROK family
HOIPEFHO_00741	1.07e-16	-	-	-	GK	-	-	-	ROK family
HOIPEFHO_00742	1.73e-136	gph	-	-	G	ko:K03292	-	ko00000	transporter
HOIPEFHO_00743	2.83e-275	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HOIPEFHO_00744	9.28e-72	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HOIPEFHO_00745	9.3e-154	-	-	-	C	-	-	-	nadph quinone reductase
HOIPEFHO_00746	1.32e-77	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_00747	4.49e-112	-	-	-	-	-	-	-	-
HOIPEFHO_00748	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOIPEFHO_00749	3.2e-70	-	-	-	-	-	-	-	-
HOIPEFHO_00750	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOIPEFHO_00751	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HOIPEFHO_00752	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOIPEFHO_00753	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HOIPEFHO_00754	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HOIPEFHO_00755	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOIPEFHO_00756	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOIPEFHO_00757	3.14e-297	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOIPEFHO_00758	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HOIPEFHO_00759	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOIPEFHO_00760	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOIPEFHO_00761	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOIPEFHO_00762	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOIPEFHO_00763	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HOIPEFHO_00764	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HOIPEFHO_00765	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HOIPEFHO_00766	1.07e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HOIPEFHO_00767	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HOIPEFHO_00768	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOIPEFHO_00769	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HOIPEFHO_00770	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HOIPEFHO_00771	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOIPEFHO_00772	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOIPEFHO_00773	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOIPEFHO_00774	2.5e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOIPEFHO_00775	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOIPEFHO_00776	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HOIPEFHO_00777	8.28e-73	-	-	-	-	-	-	-	-
HOIPEFHO_00778	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_00779	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOIPEFHO_00780	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_00781	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00782	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HOIPEFHO_00783	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HOIPEFHO_00784	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HOIPEFHO_00785	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOIPEFHO_00786	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOIPEFHO_00787	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOIPEFHO_00788	2.79e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOIPEFHO_00789	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOIPEFHO_00790	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HOIPEFHO_00791	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOIPEFHO_00792	5.79e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HOIPEFHO_00793	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HOIPEFHO_00794	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HOIPEFHO_00795	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HOIPEFHO_00796	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_00797	9.81e-27	-	-	-	-	-	-	-	-
HOIPEFHO_00800	2.97e-41	-	-	-	-	-	-	-	-
HOIPEFHO_00801	1.27e-72	-	-	-	-	-	-	-	-
HOIPEFHO_00802	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HOIPEFHO_00803	1.34e-232	-	-	-	-	-	-	-	-
HOIPEFHO_00804	1.77e-205	-	-	-	-	-	-	-	-
HOIPEFHO_00805	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HOIPEFHO_00806	1.57e-84	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HOIPEFHO_00807	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOIPEFHO_00808	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HOIPEFHO_00809	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HOIPEFHO_00810	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HOIPEFHO_00811	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HOIPEFHO_00812	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HOIPEFHO_00813	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HOIPEFHO_00814	2.03e-152	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HOIPEFHO_00815	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOIPEFHO_00816	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOIPEFHO_00817	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOIPEFHO_00818	0.0	-	-	-	S	-	-	-	membrane
HOIPEFHO_00819	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HOIPEFHO_00820	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOIPEFHO_00821	3.78e-143	-	-	-	S	-	-	-	membrane
HOIPEFHO_00822	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOIPEFHO_00823	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HOIPEFHO_00824	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOIPEFHO_00825	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOIPEFHO_00826	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOIPEFHO_00827	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HOIPEFHO_00828	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOIPEFHO_00829	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOIPEFHO_00830	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HOIPEFHO_00831	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOIPEFHO_00832	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HOIPEFHO_00833	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HOIPEFHO_00834	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HOIPEFHO_00835	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HOIPEFHO_00836	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOIPEFHO_00837	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HOIPEFHO_00838	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HOIPEFHO_00839	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOIPEFHO_00840	1.13e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOIPEFHO_00841	2.06e-122	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HOIPEFHO_00842	1.05e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HOIPEFHO_00843	1.76e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HOIPEFHO_00844	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HOIPEFHO_00845	1.02e-74	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOIPEFHO_00846	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HOIPEFHO_00847	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOIPEFHO_00848	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HOIPEFHO_00849	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HOIPEFHO_00850	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HOIPEFHO_00851	4.45e-114	-	-	-	-	-	-	-	-
HOIPEFHO_00852	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HOIPEFHO_00853	2.79e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HOIPEFHO_00854	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HOIPEFHO_00855	1.67e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HOIPEFHO_00856	2.35e-305	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HOIPEFHO_00857	1.13e-73	-	-	-	-	-	-	-	-
HOIPEFHO_00858	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOIPEFHO_00859	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HOIPEFHO_00860	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOIPEFHO_00861	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOIPEFHO_00862	4.97e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HOIPEFHO_00863	8.92e-317	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HOIPEFHO_00864	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOIPEFHO_00865	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOIPEFHO_00866	1.85e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HOIPEFHO_00867	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOIPEFHO_00868	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HOIPEFHO_00869	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HOIPEFHO_00870	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HOIPEFHO_00871	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HOIPEFHO_00872	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HOIPEFHO_00873	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOIPEFHO_00874	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HOIPEFHO_00875	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HOIPEFHO_00876	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HOIPEFHO_00877	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HOIPEFHO_00878	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HOIPEFHO_00879	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HOIPEFHO_00880	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HOIPEFHO_00881	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOIPEFHO_00882	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HOIPEFHO_00883	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOIPEFHO_00884	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HOIPEFHO_00885	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_00886	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_00887	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HOIPEFHO_00888	9.6e-73	-	-	-	-	-	-	-	-
HOIPEFHO_00889	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HOIPEFHO_00890	1.19e-151	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HOIPEFHO_00891	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_00892	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_00893	9.64e-248	-	-	-	S	-	-	-	Fn3-like domain
HOIPEFHO_00894	1.65e-80	-	-	-	-	-	-	-	-
HOIPEFHO_00895	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_00896	3e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HOIPEFHO_00897	5.71e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_00898	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HOIPEFHO_00899	1.96e-137	-	-	-	-	-	-	-	-
HOIPEFHO_00900	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HOIPEFHO_00901	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HOIPEFHO_00902	1.03e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HOIPEFHO_00903	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HOIPEFHO_00904	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOIPEFHO_00905	0.0	-	-	-	S	-	-	-	membrane
HOIPEFHO_00906	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HOIPEFHO_00907	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOIPEFHO_00908	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HOIPEFHO_00909	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HOIPEFHO_00910	4.43e-129	-	-	-	-	-	-	-	-
HOIPEFHO_00911	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOIPEFHO_00912	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOIPEFHO_00913	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_00914	1.98e-232	-	-	-	M	-	-	-	Peptidase family S41
HOIPEFHO_00915	3.51e-271	-	-	-	-	-	-	-	-
HOIPEFHO_00916	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOIPEFHO_00917	0.0	yhaN	-	-	L	-	-	-	AAA domain
HOIPEFHO_00918	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HOIPEFHO_00919	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HOIPEFHO_00920	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HOIPEFHO_00921	2.43e-18	-	-	-	-	-	-	-	-
HOIPEFHO_00922	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HOIPEFHO_00923	2.27e-270	arcT	-	-	E	-	-	-	Aminotransferase
HOIPEFHO_00924	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HOIPEFHO_00925	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HOIPEFHO_00926	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIPEFHO_00927	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HOIPEFHO_00928	7.06e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HOIPEFHO_00929	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_00930	4.85e-284	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_00931	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOIPEFHO_00932	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HOIPEFHO_00933	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HOIPEFHO_00934	0.0	celR	-	-	K	-	-	-	PRD domain
HOIPEFHO_00935	6.25e-138	-	-	-	-	-	-	-	-
HOIPEFHO_00936	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HOIPEFHO_00937	4.64e-106	-	-	-	-	-	-	-	-
HOIPEFHO_00938	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HOIPEFHO_00939	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HOIPEFHO_00942	1.79e-42	-	-	-	-	-	-	-	-
HOIPEFHO_00943	2.69e-316	dinF	-	-	V	-	-	-	MatE
HOIPEFHO_00944	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HOIPEFHO_00945	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HOIPEFHO_00946	2.97e-224	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HOIPEFHO_00947	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HOIPEFHO_00948	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HOIPEFHO_00949	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HOIPEFHO_00950	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOIPEFHO_00951	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HOIPEFHO_00952	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HOIPEFHO_00953	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HOIPEFHO_00954	3.89e-237	-	-	-	-	-	-	-	-
HOIPEFHO_00955	9.03e-16	-	-	-	-	-	-	-	-
HOIPEFHO_00956	4.29e-87	-	-	-	-	-	-	-	-
HOIPEFHO_00959	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HOIPEFHO_00960	7.12e-62	-	-	-	-	-	-	-	-
HOIPEFHO_00961	8.82e-119	-	-	-	-	-	-	-	-
HOIPEFHO_00962	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_00963	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOIPEFHO_00964	4.56e-78	-	-	-	-	-	-	-	-
HOIPEFHO_00965	5.37e-74	-	-	-	-	-	-	-	-
HOIPEFHO_00966	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HOIPEFHO_00967	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HOIPEFHO_00968	7.83e-140	-	-	-	-	-	-	-	-
HOIPEFHO_00969	2.3e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOIPEFHO_00970	2.38e-159	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HOIPEFHO_00971	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HOIPEFHO_00972	3.01e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_00973	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOIPEFHO_00975	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HOIPEFHO_00976	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_00977	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HOIPEFHO_00979	1.7e-314	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HOIPEFHO_00980	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOIPEFHO_00981	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HOIPEFHO_00982	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HOIPEFHO_00983	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOIPEFHO_00984	6.16e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_00985	1.13e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_00986	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HOIPEFHO_00987	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HOIPEFHO_00988	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HOIPEFHO_00989	8.69e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOIPEFHO_00990	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOIPEFHO_00991	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HOIPEFHO_00992	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HOIPEFHO_00993	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HOIPEFHO_00994	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HOIPEFHO_00995	9.32e-40	-	-	-	-	-	-	-	-
HOIPEFHO_00996	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOIPEFHO_00997	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOIPEFHO_00998	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HOIPEFHO_01000	4.46e-148	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HOIPEFHO_01001	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_01002	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOIPEFHO_01003	3.35e-157	-	-	-	-	-	-	-	-
HOIPEFHO_01004	8.94e-167	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOIPEFHO_01005	2.67e-180	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOIPEFHO_01006	3.75e-214	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HOIPEFHO_01007	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HOIPEFHO_01008	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HOIPEFHO_01009	1.88e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HOIPEFHO_01010	4.2e-139	-	-	-	GK	-	-	-	ROK family
HOIPEFHO_01011	1.03e-43	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOIPEFHO_01012	1.13e-153	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOIPEFHO_01013	4.86e-185	lipA	-	-	I	-	-	-	Carboxylesterase family
HOIPEFHO_01014	1.24e-144	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOIPEFHO_01016	1.04e-172	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HOIPEFHO_01017	9.14e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_01018	5.09e-124	-	-	-	-	-	-	-	-
HOIPEFHO_01019	2.22e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HOIPEFHO_01020	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HOIPEFHO_01031	5.9e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOIPEFHO_01032	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HOIPEFHO_01033	0.0	amiC	-	-	U	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_01034	6.22e-201	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIPEFHO_01035	8.2e-235	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOIPEFHO_01036	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOIPEFHO_01037	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOIPEFHO_01038	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOIPEFHO_01039	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HOIPEFHO_01040	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HOIPEFHO_01041	1.01e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HOIPEFHO_01042	3.85e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HOIPEFHO_01043	1.93e-208	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HOIPEFHO_01044	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HOIPEFHO_01045	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HOIPEFHO_01046	1.03e-34	-	-	-	-	-	-	-	-
HOIPEFHO_01047	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HOIPEFHO_01048	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HOIPEFHO_01049	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HOIPEFHO_01050	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_01051	1.72e-215	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HOIPEFHO_01052	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HOIPEFHO_01053	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HOIPEFHO_01054	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HOIPEFHO_01055	1.78e-139	-	-	-	-	-	-	-	-
HOIPEFHO_01056	2.32e-301	-	-	-	S	-	-	-	module of peptide synthetase
HOIPEFHO_01057	2.77e-64	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOIPEFHO_01058	2.01e-29	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOIPEFHO_01060	5.08e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HOIPEFHO_01061	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOIPEFHO_01062	1.52e-199	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_01063	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HOIPEFHO_01064	1.5e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOIPEFHO_01065	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HOIPEFHO_01066	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOIPEFHO_01067	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HOIPEFHO_01068	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HOIPEFHO_01069	5.22e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HOIPEFHO_01070	5.47e-180	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOIPEFHO_01071	6.34e-193	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HOIPEFHO_01072	6.26e-101	-	-	-	-	-	-	-	-
HOIPEFHO_01073	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOIPEFHO_01074	5.91e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01075	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HOIPEFHO_01076	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HOIPEFHO_01077	6.12e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HOIPEFHO_01078	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOIPEFHO_01079	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOIPEFHO_01080	1.13e-200	-	-	-	S	-	-	-	Putative adhesin
HOIPEFHO_01081	2.86e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HOIPEFHO_01082	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HOIPEFHO_01083	4.37e-127	-	-	-	KT	-	-	-	response to antibiotic
HOIPEFHO_01084	7.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HOIPEFHO_01085	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01086	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_01087	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HOIPEFHO_01088	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HOIPEFHO_01089	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_01090	1.49e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_01091	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HOIPEFHO_01092	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HOIPEFHO_01093	7.38e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HOIPEFHO_01094	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOIPEFHO_01095	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HOIPEFHO_01096	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOIPEFHO_01097	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HOIPEFHO_01098	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOIPEFHO_01099	2.02e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HOIPEFHO_01100	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOIPEFHO_01101	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HOIPEFHO_01102	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HOIPEFHO_01103	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HOIPEFHO_01104	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HOIPEFHO_01105	6.25e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOIPEFHO_01106	3.92e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HOIPEFHO_01107	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HOIPEFHO_01108	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HOIPEFHO_01109	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOIPEFHO_01110	8.78e-33	-	-	-	-	-	-	-	-
HOIPEFHO_01111	6.05e-93	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOIPEFHO_01112	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HOIPEFHO_01113	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HOIPEFHO_01114	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HOIPEFHO_01115	1.41e-211	-	-	-	-	-	-	-	-
HOIPEFHO_01116	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HOIPEFHO_01117	2.42e-143	-	-	-	-	-	-	-	-
HOIPEFHO_01118	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HOIPEFHO_01119	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HOIPEFHO_01120	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOIPEFHO_01121	6.79e-53	-	-	-	-	-	-	-	-
HOIPEFHO_01122	7.85e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01123	2.5e-66	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOIPEFHO_01124	7.8e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOIPEFHO_01125	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_01126	2.23e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HOIPEFHO_01127	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_01128	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_01129	5.36e-76	-	-	-	-	-	-	-	-
HOIPEFHO_01130	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HOIPEFHO_01131	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HOIPEFHO_01132	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HOIPEFHO_01133	2.23e-279	-	-	-	S	-	-	-	Membrane
HOIPEFHO_01134	6.92e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HOIPEFHO_01135	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_01136	3.24e-53	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HOIPEFHO_01137	5.15e-16	-	-	-	-	-	-	-	-
HOIPEFHO_01138	2.09e-85	-	-	-	-	-	-	-	-
HOIPEFHO_01139	3.03e-315	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01140	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_01141	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HOIPEFHO_01142	3.38e-74	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HOIPEFHO_01143	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HOIPEFHO_01144	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOIPEFHO_01145	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOIPEFHO_01146	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOIPEFHO_01147	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HOIPEFHO_01148	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOIPEFHO_01149	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HOIPEFHO_01150	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HOIPEFHO_01152	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HOIPEFHO_01153	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HOIPEFHO_01154	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOIPEFHO_01155	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOIPEFHO_01156	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOIPEFHO_01157	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HOIPEFHO_01158	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HOIPEFHO_01159	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HOIPEFHO_01160	2.52e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOIPEFHO_01161	3.52e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HOIPEFHO_01162	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HOIPEFHO_01163	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOIPEFHO_01164	2.09e-243	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOIPEFHO_01165	2.61e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HOIPEFHO_01166	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOIPEFHO_01167	3.35e-170	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HOIPEFHO_01168	7.44e-203	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_01169	2.77e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_01170	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HOIPEFHO_01171	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HOIPEFHO_01172	1.43e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOIPEFHO_01173	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOIPEFHO_01174	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HOIPEFHO_01175	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOIPEFHO_01176	1.51e-188	-	-	-	-	-	-	-	-
HOIPEFHO_01177	1.78e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HOIPEFHO_01178	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HOIPEFHO_01179	2.58e-163	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HOIPEFHO_01180	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
HOIPEFHO_01181	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HOIPEFHO_01182	3.62e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HOIPEFHO_01183	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOIPEFHO_01184	4.01e-36	-	-	-	-	-	-	-	-
HOIPEFHO_01185	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HOIPEFHO_01186	2.31e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HOIPEFHO_01187	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HOIPEFHO_01188	2.37e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HOIPEFHO_01189	8.29e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOIPEFHO_01190	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOIPEFHO_01191	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HOIPEFHO_01192	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HOIPEFHO_01193	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HOIPEFHO_01194	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HOIPEFHO_01195	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HOIPEFHO_01196	2.04e-177	-	-	-	-	-	-	-	-
HOIPEFHO_01197	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
HOIPEFHO_01198	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOIPEFHO_01199	4.31e-191	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HOIPEFHO_01200	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOIPEFHO_01201	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HOIPEFHO_01202	5.3e-49	-	-	-	-	-	-	-	-
HOIPEFHO_01203	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HOIPEFHO_01204	5.67e-27	-	-	-	M	ko:K21493	-	ko00000,ko01000,ko02048	self proteolysis
HOIPEFHO_01205	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HOIPEFHO_01206	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOIPEFHO_01207	3.56e-84	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HOIPEFHO_01208	4.35e-118	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HOIPEFHO_01209	6.21e-207	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOIPEFHO_01210	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HOIPEFHO_01211	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOIPEFHO_01212	1.87e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HOIPEFHO_01213	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HOIPEFHO_01215	2.91e-54	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HOIPEFHO_01216	1.29e-66	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HOIPEFHO_01217	8.6e-272	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HOIPEFHO_01219	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOIPEFHO_01220	6.59e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HOIPEFHO_01221	3.74e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HOIPEFHO_01222	8.73e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HOIPEFHO_01223	4.65e-229	-	-	-	-	-	-	-	-
HOIPEFHO_01224	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HOIPEFHO_01225	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HOIPEFHO_01226	1.7e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOIPEFHO_01227	1.14e-173	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOIPEFHO_01228	6.97e-209	-	-	-	GK	-	-	-	ROK family
HOIPEFHO_01229	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_01230	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01231	1.02e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HOIPEFHO_01232	9.68e-34	-	-	-	-	-	-	-	-
HOIPEFHO_01233	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01234	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HOIPEFHO_01235	1.12e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOIPEFHO_01236	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HOIPEFHO_01237	0.0	-	-	-	L	-	-	-	DNA helicase
HOIPEFHO_01238	2.63e-90	-	-	-	-	-	-	-	-
HOIPEFHO_01239	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HOIPEFHO_01240	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIPEFHO_01241	8.12e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HOIPEFHO_01242	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HOIPEFHO_01243	1.06e-184	-	-	-	-	-	-	-	-
HOIPEFHO_01244	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HOIPEFHO_01245	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOIPEFHO_01246	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOIPEFHO_01247	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HOIPEFHO_01248	2.21e-56	-	-	-	-	-	-	-	-
HOIPEFHO_01249	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HOIPEFHO_01250	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HOIPEFHO_01251	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HOIPEFHO_01252	7.54e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HOIPEFHO_01253	1.17e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HOIPEFHO_01254	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HOIPEFHO_01255	7.87e-243	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HOIPEFHO_01256	7.08e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HOIPEFHO_01257	2.06e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HOIPEFHO_01258	5.16e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HOIPEFHO_01259	4.67e-215	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HOIPEFHO_01260	1.01e-23	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HOIPEFHO_01261	6.14e-53	-	-	-	-	-	-	-	-
HOIPEFHO_01262	1.93e-289	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01263	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HOIPEFHO_01264	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HOIPEFHO_01265	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HOIPEFHO_01266	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HOIPEFHO_01267	2.98e-90	-	-	-	-	-	-	-	-
HOIPEFHO_01268	1.22e-125	-	-	-	-	-	-	-	-
HOIPEFHO_01269	5.92e-67	-	-	-	-	-	-	-	-
HOIPEFHO_01270	1.96e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOIPEFHO_01271	2.84e-110	-	-	-	-	-	-	-	-
HOIPEFHO_01272	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HOIPEFHO_01273	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01274	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HOIPEFHO_01275	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOIPEFHO_01276	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOIPEFHO_01277	3.48e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_01278	1.37e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HOIPEFHO_01279	9.01e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOIPEFHO_01280	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOIPEFHO_01281	1.2e-91	-	-	-	-	-	-	-	-
HOIPEFHO_01282	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOIPEFHO_01283	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HOIPEFHO_01284	2.28e-114	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HOIPEFHO_01285	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HOIPEFHO_01286	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOIPEFHO_01287	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HOIPEFHO_01288	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HOIPEFHO_01289	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOIPEFHO_01290	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOIPEFHO_01291	3.81e-18	-	-	-	-	-	-	-	-
HOIPEFHO_01292	3.69e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOIPEFHO_01293	4.56e-210	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HOIPEFHO_01294	1.35e-78	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HOIPEFHO_01295	6.33e-46	-	-	-	-	-	-	-	-
HOIPEFHO_01296	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HOIPEFHO_01297	1.11e-146	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HOIPEFHO_01298	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOIPEFHO_01299	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIPEFHO_01300	1.08e-101	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOIPEFHO_01301	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_01302	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_01303	2.95e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HOIPEFHO_01305	2.18e-285	-	-	-	M	-	-	-	domain protein
HOIPEFHO_01306	4.44e-183	-	-	-	M	-	-	-	domain protein
HOIPEFHO_01307	1.72e-212	mleR	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_01308	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOIPEFHO_01309	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HOIPEFHO_01310	1.92e-209	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HOIPEFHO_01311	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOIPEFHO_01312	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOIPEFHO_01313	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HOIPEFHO_01314	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOIPEFHO_01315	2.07e-149	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOIPEFHO_01316	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOIPEFHO_01317	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HOIPEFHO_01318	2.03e-84	-	-	-	-	-	-	-	-
HOIPEFHO_01319	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HOIPEFHO_01320	1.21e-73	-	-	-	-	-	-	-	-
HOIPEFHO_01321	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_01322	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HOIPEFHO_01323	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOIPEFHO_01324	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01325	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_01326	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
HOIPEFHO_01327	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_01328	2.18e-99	-	-	-	M	-	-	-	LysM domain
HOIPEFHO_01329	1.44e-128	-	-	-	M	-	-	-	Lysin motif
HOIPEFHO_01330	2.32e-137	-	-	-	S	-	-	-	SdpI/YhfL protein family
HOIPEFHO_01331	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HOIPEFHO_01332	6.45e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOIPEFHO_01333	8.76e-121	-	-	-	-	-	-	-	-
HOIPEFHO_01334	6.68e-156	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HOIPEFHO_01335	1.22e-272	-	-	-	T	-	-	-	diguanylate cyclase
HOIPEFHO_01336	3.55e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOIPEFHO_01337	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HOIPEFHO_01338	1.43e-57	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HOIPEFHO_01339	6.88e-151	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HOIPEFHO_01340	2.66e-38	-	-	-	-	-	-	-	-
HOIPEFHO_01341	1e-62	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_01342	1.58e-47	-	-	-	C	-	-	-	Flavodoxin
HOIPEFHO_01343	8.31e-204	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HOIPEFHO_01344	7.51e-173	-	-	-	C	-	-	-	Aldo/keto reductase family
HOIPEFHO_01345	5.31e-102	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_01346	1.91e-44	-	-	-	C	-	-	-	Flavodoxin
HOIPEFHO_01347	3.99e-14	-	-	-	L	ko:K07487	-	ko00000	Transposase
HOIPEFHO_01348	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOIPEFHO_01349	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HOIPEFHO_01350	1.96e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HOIPEFHO_01351	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HOIPEFHO_01352	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HOIPEFHO_01353	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HOIPEFHO_01354	5.98e-72	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_01355	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HOIPEFHO_01356	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOIPEFHO_01358	8.03e-28	-	-	-	-	-	-	-	-
HOIPEFHO_01359	3.75e-122	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HOIPEFHO_01360	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HOIPEFHO_01361	3.59e-130	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HOIPEFHO_01362	1.03e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HOIPEFHO_01363	1.04e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HOIPEFHO_01364	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HOIPEFHO_01365	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOIPEFHO_01366	4.08e-107	cvpA	-	-	S	-	-	-	Colicin V production protein
HOIPEFHO_01367	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOIPEFHO_01368	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_01370	4.54e-54	-	-	-	-	-	-	-	-
HOIPEFHO_01372	7.76e-186	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HOIPEFHO_01373	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HOIPEFHO_01374	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_01375	1.66e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_01376	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HOIPEFHO_01377	1.12e-129	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_01378	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOIPEFHO_01379	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HOIPEFHO_01380	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOIPEFHO_01381	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOIPEFHO_01382	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOIPEFHO_01383	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HOIPEFHO_01384	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOIPEFHO_01385	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HOIPEFHO_01386	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HOIPEFHO_01387	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HOIPEFHO_01388	8.19e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOIPEFHO_01389	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HOIPEFHO_01390	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HOIPEFHO_01391	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HOIPEFHO_01392	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOIPEFHO_01393	3.81e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HOIPEFHO_01394	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HOIPEFHO_01395	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HOIPEFHO_01396	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HOIPEFHO_01397	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HOIPEFHO_01398	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HOIPEFHO_01399	6.07e-33	-	-	-	-	-	-	-	-
HOIPEFHO_01400	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HOIPEFHO_01401	1.59e-76	-	-	-	-	-	-	-	-
HOIPEFHO_01402	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HOIPEFHO_01403	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOIPEFHO_01404	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HOIPEFHO_01405	1.19e-169	-	-	-	-	-	-	-	-
HOIPEFHO_01406	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HOIPEFHO_01407	6.77e-154	azlC	-	-	E	-	-	-	branched-chain amino acid
HOIPEFHO_01408	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HOIPEFHO_01409	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HOIPEFHO_01410	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HOIPEFHO_01411	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOIPEFHO_01412	0.0	xylP2	-	-	G	-	-	-	symporter
HOIPEFHO_01413	2.98e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOIPEFHO_01414	2.74e-63	-	-	-	-	-	-	-	-
HOIPEFHO_01415	1.91e-272	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HOIPEFHO_01416	2.62e-89	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_01417	4.77e-161	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HOIPEFHO_01418	2.98e-215	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HOIPEFHO_01419	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HOIPEFHO_01420	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HOIPEFHO_01421	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HOIPEFHO_01422	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOIPEFHO_01423	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HOIPEFHO_01424	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOIPEFHO_01425	4.15e-153	-	-	-	I	-	-	-	phosphatase
HOIPEFHO_01426	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOIPEFHO_01427	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOIPEFHO_01428	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_01429	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_01430	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HOIPEFHO_01431	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HOIPEFHO_01432	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HOIPEFHO_01433	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOIPEFHO_01441	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HOIPEFHO_01442	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOIPEFHO_01443	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_01444	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOIPEFHO_01445	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOIPEFHO_01446	1.81e-150	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HOIPEFHO_01447	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOIPEFHO_01448	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOIPEFHO_01449	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOIPEFHO_01450	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HOIPEFHO_01451	3.05e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOIPEFHO_01452	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HOIPEFHO_01453	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOIPEFHO_01454	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOIPEFHO_01455	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOIPEFHO_01456	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOIPEFHO_01457	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOIPEFHO_01458	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOIPEFHO_01459	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HOIPEFHO_01460	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOIPEFHO_01461	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOIPEFHO_01462	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOIPEFHO_01463	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOIPEFHO_01464	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOIPEFHO_01465	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOIPEFHO_01466	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOIPEFHO_01467	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOIPEFHO_01468	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HOIPEFHO_01469	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOIPEFHO_01470	8.45e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOIPEFHO_01471	3.72e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOIPEFHO_01472	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOIPEFHO_01473	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOIPEFHO_01474	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOIPEFHO_01475	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOIPEFHO_01476	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HOIPEFHO_01477	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOIPEFHO_01478	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HOIPEFHO_01479	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HOIPEFHO_01480	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HOIPEFHO_01481	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HOIPEFHO_01482	6.21e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOIPEFHO_01483	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOIPEFHO_01484	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOIPEFHO_01485	2.39e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOIPEFHO_01486	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOIPEFHO_01487	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOIPEFHO_01488	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HOIPEFHO_01489	8.17e-208	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HOIPEFHO_01490	2.46e-235	-	-	-	S	-	-	-	Membrane
HOIPEFHO_01491	7.79e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HOIPEFHO_01492	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOIPEFHO_01493	2.25e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOIPEFHO_01494	2.71e-234	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HOIPEFHO_01495	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOIPEFHO_01496	2.37e-280	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HOIPEFHO_01497	4.33e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HOIPEFHO_01498	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HOIPEFHO_01499	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HOIPEFHO_01500	1.28e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_01501	1.57e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HOIPEFHO_01502	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOIPEFHO_01503	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HOIPEFHO_01504	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOIPEFHO_01505	1.18e-66	-	-	-	-	-	-	-	-
HOIPEFHO_01506	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOIPEFHO_01507	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HOIPEFHO_01508	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HOIPEFHO_01509	7.83e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HOIPEFHO_01510	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HOIPEFHO_01511	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HOIPEFHO_01512	1.06e-206	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HOIPEFHO_01513	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HOIPEFHO_01514	1.98e-232	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HOIPEFHO_01516	9.54e-65	-	-	-	K	-	-	-	sequence-specific DNA binding
HOIPEFHO_01519	1.49e-68	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOIPEFHO_01520	5.83e-182	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HOIPEFHO_01521	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOIPEFHO_01522	7.81e-247	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIPEFHO_01523	5.37e-182	-	-	-	-	-	-	-	-
HOIPEFHO_01524	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOIPEFHO_01525	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01526	5.63e-89	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HOIPEFHO_01527	4.03e-168	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HOIPEFHO_01529	2.46e-58	-	-	-	S	-	-	-	Bacteriophage holin
HOIPEFHO_01530	4.55e-64	-	-	-	-	-	-	-	-
HOIPEFHO_01531	6.54e-234	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HOIPEFHO_01534	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOIPEFHO_01535	4.07e-11	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOIPEFHO_01538	2.84e-123	-	-	-	S	-	-	-	Prophage endopeptidase tail
HOIPEFHO_01540	2.04e-179	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HOIPEFHO_01543	3.24e-58	-	-	-	N	-	-	-	domain, Protein
HOIPEFHO_01548	4.22e-06	-	-	-	-	-	-	-	-
HOIPEFHO_01549	2.84e-134	-	-	-	-	-	-	-	-
HOIPEFHO_01552	4.97e-55	-	-	-	S	-	-	-	Phage minor capsid protein 2
HOIPEFHO_01553	7.55e-137	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HOIPEFHO_01554	1.72e-235	-	-	-	S	-	-	-	Phage terminase, large subunit, PBSX family
HOIPEFHO_01555	6.24e-72	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HOIPEFHO_01556	1.99e-23	-	-	-	-	-	-	-	-
HOIPEFHO_01557	1.55e-24	-	-	-	-	-	-	-	-
HOIPEFHO_01562	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HOIPEFHO_01563	5.18e-08	-	-	-	-	-	-	-	-
HOIPEFHO_01564	5.7e-87	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HOIPEFHO_01565	1.29e-80	-	-	-	-	-	-	-	-
HOIPEFHO_01566	2.67e-66	-	-	-	-	-	-	-	-
HOIPEFHO_01567	6.41e-207	-	-	-	L	-	-	-	DnaD domain protein
HOIPEFHO_01568	1.72e-172	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HOIPEFHO_01569	6.94e-05	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
HOIPEFHO_01570	2.08e-22	-	-	-	K	ko:K22299	-	ko00000,ko03000	sequence-specific DNA binding
HOIPEFHO_01573	1.27e-16	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HOIPEFHO_01576	6.54e-92	-	-	-	-	-	-	-	-
HOIPEFHO_01578	1.65e-101	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
HOIPEFHO_01581	2.61e-16	-	-	-	-	-	-	-	-
HOIPEFHO_01582	2.18e-20	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOIPEFHO_01583	5.54e-199	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOIPEFHO_01585	8.08e-40	-	-	-	-	-	-	-	-
HOIPEFHO_01587	1.28e-51	-	-	-	-	-	-	-	-
HOIPEFHO_01588	1.09e-56	-	-	-	-	-	-	-	-
HOIPEFHO_01589	1.27e-109	-	-	-	K	-	-	-	MarR family
HOIPEFHO_01590	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HOIPEFHO_01591	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HOIPEFHO_01592	6.58e-24	-	-	-	-	-	-	-	-
HOIPEFHO_01593	3.26e-24	-	-	-	-	-	-	-	-
HOIPEFHO_01594	1.56e-22	-	-	-	-	-	-	-	-
HOIPEFHO_01595	1.07e-26	-	-	-	-	-	-	-	-
HOIPEFHO_01596	9.35e-24	-	-	-	-	-	-	-	-
HOIPEFHO_01597	9.35e-24	-	-	-	-	-	-	-	-
HOIPEFHO_01598	2.16e-26	-	-	-	-	-	-	-	-
HOIPEFHO_01599	4.63e-24	-	-	-	-	-	-	-	-
HOIPEFHO_01600	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HOIPEFHO_01601	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOIPEFHO_01602	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01603	2.1e-33	-	-	-	-	-	-	-	-
HOIPEFHO_01604	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HOIPEFHO_01605	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HOIPEFHO_01606	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HOIPEFHO_01607	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HOIPEFHO_01608	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HOIPEFHO_01609	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HOIPEFHO_01610	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HOIPEFHO_01611	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HOIPEFHO_01613	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HOIPEFHO_01614	1.08e-63	-	-	-	-	-	-	-	-
HOIPEFHO_01615	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HOIPEFHO_01616	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HOIPEFHO_01617	2.68e-32	-	-	-	-	-	-	-	-
HOIPEFHO_01619	2e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_01620	2.47e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HOIPEFHO_01621	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HOIPEFHO_01622	2.29e-48	-	-	-	-	-	-	-	-
HOIPEFHO_01623	9.17e-45	-	-	-	-	-	-	-	-
HOIPEFHO_01624	2.58e-274	-	-	-	T	-	-	-	diguanylate cyclase
HOIPEFHO_01626	6.19e-208	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_01627	2.95e-207	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HOIPEFHO_01628	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HOIPEFHO_01629	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HOIPEFHO_01630	0.0	ycaM	-	-	E	-	-	-	amino acid
HOIPEFHO_01631	2.1e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HOIPEFHO_01632	4.3e-44	-	-	-	-	-	-	-	-
HOIPEFHO_01633	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HOIPEFHO_01634	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HOIPEFHO_01635	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HOIPEFHO_01636	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HOIPEFHO_01637	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HOIPEFHO_01638	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HOIPEFHO_01639	3.26e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HOIPEFHO_01640	2.05e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOIPEFHO_01641	5.06e-196	-	-	-	S	-	-	-	hydrolase
HOIPEFHO_01642	7.63e-107	-	-	-	-	-	-	-	-
HOIPEFHO_01643	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HOIPEFHO_01644	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HOIPEFHO_01645	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HOIPEFHO_01646	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOIPEFHO_01647	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HOIPEFHO_01648	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_01649	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOIPEFHO_01650	4.77e-316	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HOIPEFHO_01651	8.66e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HOIPEFHO_01652	1.08e-248	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system, permease component
HOIPEFHO_01653	9.69e-149	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_01654	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOIPEFHO_01655	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HOIPEFHO_01656	6.58e-262	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HOIPEFHO_01657	3.64e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
HOIPEFHO_01658	1.65e-267	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HOIPEFHO_01659	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HOIPEFHO_01660	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HOIPEFHO_01661	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HOIPEFHO_01662	3.24e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HOIPEFHO_01663	1.03e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOIPEFHO_01664	4.72e-40	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HOIPEFHO_01665	7.71e-185	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOIPEFHO_01666	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HOIPEFHO_01667	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOIPEFHO_01669	1.21e-69	-	-	-	-	-	-	-	-
HOIPEFHO_01670	4.34e-151	-	-	-	-	-	-	-	-
HOIPEFHO_01671	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HOIPEFHO_01672	8.32e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOIPEFHO_01673	4.79e-13	-	-	-	-	-	-	-	-
HOIPEFHO_01674	4.87e-66	-	-	-	-	-	-	-	-
HOIPEFHO_01675	1.76e-114	-	-	-	-	-	-	-	-
HOIPEFHO_01676	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HOIPEFHO_01677	1.08e-47	-	-	-	-	-	-	-	-
HOIPEFHO_01678	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HOIPEFHO_01680	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HOIPEFHO_01681	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HOIPEFHO_01682	3.16e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HOIPEFHO_01683	3.79e-66	-	-	-	L	-	-	-	Integrase
HOIPEFHO_01684	1.53e-106	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HOIPEFHO_01685	9.13e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HOIPEFHO_01686	1.38e-231	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HOIPEFHO_01687	9.81e-73	repA	-	-	S	-	-	-	Replication initiator protein A
HOIPEFHO_01688	1.77e-56	-	-	-	-	-	-	-	-
HOIPEFHO_01689	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOIPEFHO_01690	1.45e-103	-	-	-	L	-	-	-	Phage integrase family
HOIPEFHO_01691	1.24e-39	-	-	-	-	-	-	-	-
HOIPEFHO_01692	5.12e-112	-	-	-	-	-	-	-	-
HOIPEFHO_01693	4.8e-74	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HOIPEFHO_01694	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HOIPEFHO_01695	1.21e-78	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HOIPEFHO_01696	4.63e-215	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HOIPEFHO_01698	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOIPEFHO_01699	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_01701	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HOIPEFHO_01702	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HOIPEFHO_01703	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOIPEFHO_01704	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOIPEFHO_01705	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HOIPEFHO_01706	4.56e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HOIPEFHO_01707	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_01708	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOIPEFHO_01709	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOIPEFHO_01710	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOIPEFHO_01711	1.65e-266	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOIPEFHO_01712	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HOIPEFHO_01713	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOIPEFHO_01714	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOIPEFHO_01715	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOIPEFHO_01716	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HOIPEFHO_01717	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOIPEFHO_01718	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOIPEFHO_01719	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HOIPEFHO_01720	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOIPEFHO_01721	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HOIPEFHO_01722	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_01723	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOIPEFHO_01724	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOIPEFHO_01726	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_01727	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOIPEFHO_01728	5.02e-277	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOIPEFHO_01729	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HOIPEFHO_01730	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HOIPEFHO_01731	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOIPEFHO_01732	7.84e-103	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOIPEFHO_01733	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOIPEFHO_01735	8.04e-182	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOIPEFHO_01736	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HOIPEFHO_01737	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HOIPEFHO_01738	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HOIPEFHO_01739	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HOIPEFHO_01740	2.54e-50	-	-	-	-	-	-	-	-
HOIPEFHO_01742	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HOIPEFHO_01743	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOIPEFHO_01744	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HOIPEFHO_01745	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HOIPEFHO_01746	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HOIPEFHO_01747	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HOIPEFHO_01748	7.1e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOIPEFHO_01749	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_01750	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HOIPEFHO_01751	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HOIPEFHO_01752	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HOIPEFHO_01753	1.34e-153	pnb	-	-	C	-	-	-	nitroreductase
HOIPEFHO_01754	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HOIPEFHO_01755	7.46e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HOIPEFHO_01756	0.0	-	-	-	C	-	-	-	FMN_bind
HOIPEFHO_01757	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HOIPEFHO_01758	1.46e-204	-	-	-	K	-	-	-	LysR family
HOIPEFHO_01759	2.49e-95	-	-	-	C	-	-	-	FMN binding
HOIPEFHO_01760	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOIPEFHO_01761	4.06e-211	-	-	-	S	-	-	-	KR domain
HOIPEFHO_01762	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HOIPEFHO_01763	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HOIPEFHO_01764	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HOIPEFHO_01765	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HOIPEFHO_01766	1.27e-247	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOIPEFHO_01767	9.3e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOIPEFHO_01768	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HOIPEFHO_01769	9.51e-135	-	-	-	-	-	-	-	-
HOIPEFHO_01770	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HOIPEFHO_01771	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_01772	1.19e-259	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HOIPEFHO_01773	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HOIPEFHO_01774	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HOIPEFHO_01775	7.08e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HOIPEFHO_01776	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOIPEFHO_01777	8.61e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HOIPEFHO_01778	6.29e-163	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HOIPEFHO_01779	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HOIPEFHO_01780	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HOIPEFHO_01781	9.6e-121	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HOIPEFHO_01782	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HOIPEFHO_01783	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HOIPEFHO_01784	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOIPEFHO_01785	4.48e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOIPEFHO_01786	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOIPEFHO_01787	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOIPEFHO_01788	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
HOIPEFHO_01789	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOIPEFHO_01790	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOIPEFHO_01791	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOIPEFHO_01792	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HOIPEFHO_01793	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HOIPEFHO_01794	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HOIPEFHO_01795	5.12e-31	-	-	-	-	-	-	-	-
HOIPEFHO_01796	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HOIPEFHO_01797	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01798	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOIPEFHO_01799	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HOIPEFHO_01800	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HOIPEFHO_01801	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HOIPEFHO_01802	7.15e-230	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HOIPEFHO_01803	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HOIPEFHO_01804	6.63e-258	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HOIPEFHO_01805	2.26e-243	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HOIPEFHO_01806	2.71e-297	-	-	-	-	-	-	-	-
HOIPEFHO_01807	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HOIPEFHO_01808	0.0	cps4J	-	-	S	-	-	-	MatE
HOIPEFHO_01809	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HOIPEFHO_01810	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HOIPEFHO_01811	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HOIPEFHO_01812	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HOIPEFHO_01813	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOIPEFHO_01814	1.34e-61	-	-	-	-	-	-	-	-
HOIPEFHO_01815	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HOIPEFHO_01816	5.83e-179	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_01817	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HOIPEFHO_01818	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HOIPEFHO_01819	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOIPEFHO_01820	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_01821	2.25e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HOIPEFHO_01822	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HOIPEFHO_01823	6.34e-178	-	-	-	Q	-	-	-	Methyltransferase
HOIPEFHO_01824	1.75e-43	-	-	-	-	-	-	-	-
HOIPEFHO_01825	4.57e-68	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOIPEFHO_01832	4.16e-51	-	-	-	S	-	-	-	Membrane
HOIPEFHO_01835	2.9e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HOIPEFHO_01837	6.04e-87	-	-	-	S	-	-	-	DNA binding
HOIPEFHO_01840	1.38e-07	-	-	-	-	-	-	-	-
HOIPEFHO_01844	2.56e-22	-	-	-	-	-	-	-	-
HOIPEFHO_01847	3.01e-95	-	-	-	L	-	-	-	DnaD domain protein
HOIPEFHO_01848	6e-211	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HOIPEFHO_01850	5.34e-31	-	-	-	-	-	-	-	-
HOIPEFHO_01854	1.33e-40	-	-	-	S	-	-	-	YopX protein
HOIPEFHO_01855	1.23e-49	-	-	-	-	-	-	-	-
HOIPEFHO_01856	6.63e-41	-	-	-	-	-	-	-	-
HOIPEFHO_01857	1.96e-83	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HOIPEFHO_01859	4.49e-17	-	-	-	V	-	-	-	HNH nucleases
HOIPEFHO_01860	2.51e-111	-	-	-	L	-	-	-	HNH nucleases
HOIPEFHO_01861	1.91e-104	-	-	-	S	-	-	-	Phage terminase, small subunit
HOIPEFHO_01862	0.0	-	-	-	S	-	-	-	Phage Terminase
HOIPEFHO_01863	9.49e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HOIPEFHO_01864	1.47e-285	-	-	-	S	-	-	-	Phage portal protein
HOIPEFHO_01865	5.99e-164	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HOIPEFHO_01866	1.31e-269	-	-	-	S	-	-	-	peptidase activity
HOIPEFHO_01867	2.28e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HOIPEFHO_01868	2.81e-31	-	-	-	S	-	-	-	Phage head-tail joining protein
HOIPEFHO_01869	1.54e-49	-	-	-	-	-	-	-	-
HOIPEFHO_01870	3.57e-33	-	-	-	-	-	-	-	-
HOIPEFHO_01871	3.67e-91	-	-	-	S	-	-	-	Phage tail tube protein
HOIPEFHO_01873	1.12e-05	-	-	-	-	-	-	-	-
HOIPEFHO_01874	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HOIPEFHO_01875	0.0	-	-	-	S	-	-	-	Phage tail protein
HOIPEFHO_01876	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HOIPEFHO_01880	2.5e-100	-	-	-	-	-	-	-	-
HOIPEFHO_01881	1.97e-32	-	-	-	-	-	-	-	-
HOIPEFHO_01882	4.05e-263	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOIPEFHO_01883	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
HOIPEFHO_01884	4.55e-56	-	-	-	S	-	-	-	Bacteriophage holin
HOIPEFHO_01886	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HOIPEFHO_01887	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_01888	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOIPEFHO_01889	5.43e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HOIPEFHO_01890	8.9e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HOIPEFHO_01891	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HOIPEFHO_01892	3.81e-87	-	-	-	-	-	-	-	-
HOIPEFHO_01893	5.61e-98	-	-	-	-	-	-	-	-
HOIPEFHO_01894	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HOIPEFHO_01895	7.8e-123	-	-	-	-	-	-	-	-
HOIPEFHO_01896	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOIPEFHO_01897	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HOIPEFHO_01898	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HOIPEFHO_01899	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HOIPEFHO_01900	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HOIPEFHO_01901	6.63e-63	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HOIPEFHO_01902	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIPEFHO_01903	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HOIPEFHO_01904	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HOIPEFHO_01905	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOIPEFHO_01906	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HOIPEFHO_01907	4e-112	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOIPEFHO_01908	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOIPEFHO_01909	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HOIPEFHO_01910	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HOIPEFHO_01911	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOIPEFHO_01912	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOIPEFHO_01913	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HOIPEFHO_01914	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HOIPEFHO_01915	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HOIPEFHO_01916	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HOIPEFHO_01917	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOIPEFHO_01918	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOIPEFHO_01919	0.0	-	-	-	G	-	-	-	Major Facilitator
HOIPEFHO_01920	2.12e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOIPEFHO_01921	1.63e-121	-	-	-	-	-	-	-	-
HOIPEFHO_01922	1.24e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOIPEFHO_01923	1.47e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HOIPEFHO_01924	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOIPEFHO_01925	1.8e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOIPEFHO_01926	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HOIPEFHO_01927	6.88e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HOIPEFHO_01928	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOIPEFHO_01929	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOIPEFHO_01930	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HOIPEFHO_01931	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOIPEFHO_01932	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HOIPEFHO_01933	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HOIPEFHO_01934	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIPEFHO_01935	5.42e-296	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HOIPEFHO_01936	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIPEFHO_01937	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HOIPEFHO_01938	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOIPEFHO_01939	1.24e-159	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOIPEFHO_01942	1.73e-67	-	-	-	-	-	-	-	-
HOIPEFHO_01943	4.78e-65	-	-	-	-	-	-	-	-
HOIPEFHO_01944	4.82e-107	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HOIPEFHO_01945	5.85e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HOIPEFHO_01946	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOIPEFHO_01947	2.56e-76	-	-	-	-	-	-	-	-
HOIPEFHO_01948	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOIPEFHO_01949	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOIPEFHO_01950	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HOIPEFHO_01951	1.72e-209	-	-	-	G	-	-	-	Fructosamine kinase
HOIPEFHO_01952	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HOIPEFHO_01953	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HOIPEFHO_01954	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HOIPEFHO_01955	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOIPEFHO_01956	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOIPEFHO_01957	2.61e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIPEFHO_01958	5.8e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOIPEFHO_01959	7.06e-164	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HOIPEFHO_01960	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HOIPEFHO_01961	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HOIPEFHO_01962	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HOIPEFHO_01963	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HOIPEFHO_01964	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOIPEFHO_01965	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HOIPEFHO_01966	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOIPEFHO_01967	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HOIPEFHO_01968	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HOIPEFHO_01969	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HOIPEFHO_01970	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOIPEFHO_01971	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOIPEFHO_01972	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HOIPEFHO_01973	1.42e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01974	1.5e-255	-	-	-	-	-	-	-	-
HOIPEFHO_01975	1.01e-251	-	-	-	-	-	-	-	-
HOIPEFHO_01976	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOIPEFHO_01977	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_01978	0.000123	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HOIPEFHO_01979	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOIPEFHO_01980	1.93e-94	-	-	-	K	-	-	-	MarR family
HOIPEFHO_01981	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOIPEFHO_01983	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_01984	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HOIPEFHO_01985	5.11e-266	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOIPEFHO_01986	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HOIPEFHO_01987	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HOIPEFHO_01989	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HOIPEFHO_01990	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_01991	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HOIPEFHO_01992	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_01993	3.59e-204	-	-	-	S	-	-	-	Alpha beta hydrolase
HOIPEFHO_01994	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOIPEFHO_01995	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HOIPEFHO_01996	1.77e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HOIPEFHO_01997	4.46e-257	-	-	-	-	-	-	-	-
HOIPEFHO_01998	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HOIPEFHO_01999	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HOIPEFHO_02000	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HOIPEFHO_02001	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HOIPEFHO_02002	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HOIPEFHO_02003	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOIPEFHO_02004	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HOIPEFHO_02005	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HOIPEFHO_02006	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOIPEFHO_02007	6.45e-111	-	-	-	-	-	-	-	-
HOIPEFHO_02008	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HOIPEFHO_02009	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOIPEFHO_02010	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HOIPEFHO_02011	2.16e-39	-	-	-	-	-	-	-	-
HOIPEFHO_02012	4.26e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HOIPEFHO_02013	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOIPEFHO_02014	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOIPEFHO_02015	1.02e-155	-	-	-	S	-	-	-	repeat protein
HOIPEFHO_02016	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HOIPEFHO_02017	0.0	-	-	-	N	-	-	-	domain, Protein
HOIPEFHO_02018	1.66e-246	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HOIPEFHO_02019	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_02020	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HOIPEFHO_02021	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HOIPEFHO_02022	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOIPEFHO_02023	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HOIPEFHO_02024	4.88e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HOIPEFHO_02025	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOIPEFHO_02026	7.74e-47	-	-	-	-	-	-	-	-
HOIPEFHO_02027	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HOIPEFHO_02028	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HOIPEFHO_02029	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOIPEFHO_02030	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HOIPEFHO_02031	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HOIPEFHO_02032	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HOIPEFHO_02033	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOIPEFHO_02034	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOIPEFHO_02035	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HOIPEFHO_02036	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HOIPEFHO_02037	1.67e-251	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOIPEFHO_02038	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOIPEFHO_02039	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOIPEFHO_02040	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOIPEFHO_02041	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HOIPEFHO_02042	7.08e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOIPEFHO_02043	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HOIPEFHO_02044	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HOIPEFHO_02045	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HOIPEFHO_02046	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HOIPEFHO_02047	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOIPEFHO_02048	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HOIPEFHO_02049	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOIPEFHO_02051	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HOIPEFHO_02052	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOIPEFHO_02053	6.16e-48	-	-	-	-	-	-	-	-
HOIPEFHO_02054	5.79e-21	-	-	-	-	-	-	-	-
HOIPEFHO_02055	1.29e-54	-	-	-	S	-	-	-	transglycosylase associated protein
HOIPEFHO_02056	4e-40	-	-	-	S	-	-	-	CsbD-like
HOIPEFHO_02057	1.06e-53	-	-	-	-	-	-	-	-
HOIPEFHO_02058	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOIPEFHO_02059	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HOIPEFHO_02060	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOIPEFHO_02061	2.99e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HOIPEFHO_02062	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HOIPEFHO_02063	8.78e-67	-	-	-	-	-	-	-	-
HOIPEFHO_02064	3.93e-59	-	-	-	-	-	-	-	-
HOIPEFHO_02065	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOIPEFHO_02066	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOIPEFHO_02067	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HOIPEFHO_02068	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HOIPEFHO_02069	1.38e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HOIPEFHO_02070	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HOIPEFHO_02071	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HOIPEFHO_02072	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HOIPEFHO_02073	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HOIPEFHO_02074	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HOIPEFHO_02075	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HOIPEFHO_02076	2.1e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HOIPEFHO_02077	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HOIPEFHO_02078	1.03e-106	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HOIPEFHO_02079	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HOIPEFHO_02080	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HOIPEFHO_02081	3.25e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HOIPEFHO_02083	3.29e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOIPEFHO_02084	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02085	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOIPEFHO_02086	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HOIPEFHO_02087	5.48e-140	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_02088	1.02e-216	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOIPEFHO_02089	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOIPEFHO_02090	3.27e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HOIPEFHO_02091	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HOIPEFHO_02092	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOIPEFHO_02093	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HOIPEFHO_02094	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HOIPEFHO_02096	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HOIPEFHO_02097	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_02098	3.65e-308	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOIPEFHO_02099	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HOIPEFHO_02100	1.48e-83	-	-	-	S	-	-	-	SnoaL-like domain
HOIPEFHO_02101	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HOIPEFHO_02102	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HOIPEFHO_02103	8.75e-72	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_02104	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HOIPEFHO_02105	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HOIPEFHO_02106	5.07e-158	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HOIPEFHO_02107	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOIPEFHO_02108	6.79e-249	-	-	-	-	-	-	-	-
HOIPEFHO_02109	1.23e-185	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HOIPEFHO_02110	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HOIPEFHO_02111	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HOIPEFHO_02112	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HOIPEFHO_02113	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HOIPEFHO_02114	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOIPEFHO_02115	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOIPEFHO_02116	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOIPEFHO_02117	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HOIPEFHO_02118	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOIPEFHO_02119	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HOIPEFHO_02120	7.75e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HOIPEFHO_02122	6.24e-25	plnR	-	-	-	-	-	-	-
HOIPEFHO_02123	1.15e-43	-	-	-	-	-	-	-	-
HOIPEFHO_02124	3.65e-66	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIPEFHO_02128	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIPEFHO_02129	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOIPEFHO_02130	8.38e-192	-	-	-	S	-	-	-	hydrolase
HOIPEFHO_02131	4.75e-212	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02132	5.9e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HOIPEFHO_02133	2.24e-262	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HOIPEFHO_02134	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOIPEFHO_02135	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOIPEFHO_02136	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HOIPEFHO_02137	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HOIPEFHO_02138	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HOIPEFHO_02139	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02140	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOIPEFHO_02141	1.94e-100	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HOIPEFHO_02142	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_02143	1.07e-208	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_02144	2.12e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HOIPEFHO_02145	2.43e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOIPEFHO_02146	2.16e-103	-	-	-	-	-	-	-	-
HOIPEFHO_02147	8.37e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HOIPEFHO_02148	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HOIPEFHO_02149	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HOIPEFHO_02150	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HOIPEFHO_02151	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HOIPEFHO_02152	4.83e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HOIPEFHO_02153	8.61e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HOIPEFHO_02154	8.95e-60	-	-	-	-	-	-	-	-
HOIPEFHO_02155	7.39e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HOIPEFHO_02156	1.66e-305	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HOIPEFHO_02157	8.56e-193	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOIPEFHO_02158	8.44e-119	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOIPEFHO_02159	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HOIPEFHO_02160	6.53e-58	-	-	-	-	-	-	-	-
HOIPEFHO_02161	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HOIPEFHO_02162	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HOIPEFHO_02163	1.1e-280	-	-	-	-	-	-	-	-
HOIPEFHO_02164	4.23e-184	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HOIPEFHO_02165	1.45e-218	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HOIPEFHO_02166	2.18e-185	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HOIPEFHO_02167	3.55e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HOIPEFHO_02168	1.12e-130	-	-	-	K	-	-	-	FR47-like protein
HOIPEFHO_02169	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HOIPEFHO_02170	2.31e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HOIPEFHO_02171	1.53e-241	-	-	-	-	-	-	-	-
HOIPEFHO_02172	5.03e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOIPEFHO_02173	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_02174	9.54e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOIPEFHO_02175	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HOIPEFHO_02176	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HOIPEFHO_02177	9.05e-55	-	-	-	-	-	-	-	-
HOIPEFHO_02178	6.71e-284	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HOIPEFHO_02179	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOIPEFHO_02180	3.95e-254	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HOIPEFHO_02181	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HOIPEFHO_02182	1.3e-134	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOIPEFHO_02183	1.44e-104	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02185	0.0	-	-	-	C	-	-	-	FMN_bind
HOIPEFHO_02186	1.37e-220	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02187	2.67e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_02188	2.49e-178	-	-	-	K	-	-	-	sequence-specific DNA binding
HOIPEFHO_02189	2.48e-63	-	-	-	S	-	-	-	AAA domain
HOIPEFHO_02190	9.7e-34	-	-	-	S	-	-	-	AAA domain
HOIPEFHO_02191	1.42e-08	-	-	-	-	-	-	-	-
HOIPEFHO_02192	9.1e-47	-	-	-	M	-	-	-	MucBP domain
HOIPEFHO_02193	0.0	-	-	-	M	-	-	-	MucBP domain
HOIPEFHO_02194	1.39e-118	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HOIPEFHO_02195	5.62e-56	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HOIPEFHO_02196	4.61e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOIPEFHO_02197	6.25e-83	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HOIPEFHO_02198	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HOIPEFHO_02199	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HOIPEFHO_02200	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HOIPEFHO_02201	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
HOIPEFHO_02202	1.22e-210	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HOIPEFHO_02203	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HOIPEFHO_02204	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HOIPEFHO_02205	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HOIPEFHO_02206	5.74e-32	-	-	-	-	-	-	-	-
HOIPEFHO_02207	1.37e-116	-	-	-	-	-	-	-	-
HOIPEFHO_02208	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HOIPEFHO_02209	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HOIPEFHO_02210	2.09e-60	-	-	-	S	-	-	-	MORN repeat
HOIPEFHO_02211	1.23e-266	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HOIPEFHO_02212	5.06e-297	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HOIPEFHO_02213	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOIPEFHO_02214	2.13e-167	-	-	-	L	-	-	-	Helix-turn-helix domain
HOIPEFHO_02215	1.07e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HOIPEFHO_02216	3.87e-141	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HOIPEFHO_02217	7.8e-58	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_02218	1.26e-70	-	-	-	-	-	-	-	-
HOIPEFHO_02219	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOIPEFHO_02220	2e-264	yacL	-	-	S	-	-	-	domain protein
HOIPEFHO_02221	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOIPEFHO_02222	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOIPEFHO_02223	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOIPEFHO_02224	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOIPEFHO_02225	5.03e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HOIPEFHO_02226	3.09e-128	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HOIPEFHO_02227	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOIPEFHO_02228	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOIPEFHO_02229	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HOIPEFHO_02230	1.63e-201	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_02231	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOIPEFHO_02232	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOIPEFHO_02233	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOIPEFHO_02234	3.22e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOIPEFHO_02235	3.38e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HOIPEFHO_02236	3.93e-85	-	-	-	L	-	-	-	nuclease
HOIPEFHO_02237	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOIPEFHO_02238	1.26e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_02239	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HOIPEFHO_02240	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOIPEFHO_02241	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOIPEFHO_02242	5.92e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HOIPEFHO_02243	2.73e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HOIPEFHO_02244	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOIPEFHO_02245	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOIPEFHO_02246	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOIPEFHO_02247	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOIPEFHO_02248	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HOIPEFHO_02249	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOIPEFHO_02250	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HOIPEFHO_02251	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HOIPEFHO_02252	9.89e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HOIPEFHO_02253	8.85e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOIPEFHO_02254	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HOIPEFHO_02255	7.03e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOIPEFHO_02256	5.13e-268	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HOIPEFHO_02257	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HOIPEFHO_02258	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02259	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HOIPEFHO_02260	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HOIPEFHO_02261	1.41e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HOIPEFHO_02262	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HOIPEFHO_02263	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HOIPEFHO_02264	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HOIPEFHO_02265	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOIPEFHO_02266	2.81e-36	-	-	-	-	-	-	-	-
HOIPEFHO_02267	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HOIPEFHO_02268	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HOIPEFHO_02269	1.74e-49	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_02270	1.92e-239	-	-	-	C	-	-	-	FMN_bind
HOIPEFHO_02271	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HOIPEFHO_02272	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HOIPEFHO_02273	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_02274	2.66e-172	-	-	-	-	-	-	-	-
HOIPEFHO_02275	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HOIPEFHO_02276	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOIPEFHO_02277	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOIPEFHO_02278	3e-251	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HOIPEFHO_02279	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HOIPEFHO_02280	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOIPEFHO_02281	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HOIPEFHO_02282	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOIPEFHO_02283	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOIPEFHO_02284	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HOIPEFHO_02285	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HOIPEFHO_02286	1.73e-216	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HOIPEFHO_02287	6.58e-225	-	-	-	L	-	-	-	Initiator Replication protein
HOIPEFHO_02288	1.72e-70	-	-	-	-	-	-	-	-
HOIPEFHO_02289	0.0	-	-	-	V	-	-	-	DNA restriction-modification system
HOIPEFHO_02290	0.0	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HOIPEFHO_02291	4.09e-69	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOIPEFHO_02292	1.82e-77	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HOIPEFHO_02293	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HOIPEFHO_02294	5.35e-139	-	-	-	L	-	-	-	Integrase
HOIPEFHO_02295	6.76e-83	-	-	-	-	-	-	-	-
HOIPEFHO_02297	5.64e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOIPEFHO_02299	1.02e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOIPEFHO_02300	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HOIPEFHO_02301	1.31e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HOIPEFHO_02302	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HOIPEFHO_02303	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HOIPEFHO_02304	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOIPEFHO_02305	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HOIPEFHO_02306	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOIPEFHO_02307	6.62e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HOIPEFHO_02308	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HOIPEFHO_02309	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOIPEFHO_02310	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOIPEFHO_02311	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HOIPEFHO_02312	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HOIPEFHO_02313	1.08e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HOIPEFHO_02314	1.61e-70	-	-	-	S	-	-	-	Cupin domain
HOIPEFHO_02315	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HOIPEFHO_02319	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOIPEFHO_02320	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HOIPEFHO_02322	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02323	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOIPEFHO_02324	0.0	-	-	-	S	-	-	-	MucBP domain
HOIPEFHO_02325	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOIPEFHO_02326	1.06e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_02327	1.85e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HOIPEFHO_02328	9.53e-100	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOIPEFHO_02329	1.04e-220	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOIPEFHO_02330	2.31e-95	-	-	-	M	-	-	-	LysM domain protein
HOIPEFHO_02331	1.41e-86	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HOIPEFHO_02332	2.59e-228	-	-	-	-	-	-	-	-
HOIPEFHO_02333	4.65e-168	-	-	-	-	-	-	-	-
HOIPEFHO_02334	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HOIPEFHO_02335	2.03e-75	-	-	-	-	-	-	-	-
HOIPEFHO_02336	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOIPEFHO_02337	1.26e-100	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HOIPEFHO_02338	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02339	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HOIPEFHO_02340	2.18e-53	-	-	-	-	-	-	-	-
HOIPEFHO_02341	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_02342	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02343	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02344	5.94e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HOIPEFHO_02345	3.68e-125	-	-	-	K	-	-	-	Cupin domain
HOIPEFHO_02346	8.08e-110	-	-	-	S	-	-	-	ASCH
HOIPEFHO_02347	1.88e-111	-	-	-	K	-	-	-	GNAT family
HOIPEFHO_02348	1.02e-115	-	-	-	K	-	-	-	acetyltransferase
HOIPEFHO_02349	2.06e-30	-	-	-	-	-	-	-	-
HOIPEFHO_02350	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HOIPEFHO_02351	7.53e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_02352	1.08e-243	-	-	-	-	-	-	-	-
HOIPEFHO_02353	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HOIPEFHO_02354	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HOIPEFHO_02356	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HOIPEFHO_02357	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HOIPEFHO_02358	7.28e-42	-	-	-	-	-	-	-	-
HOIPEFHO_02359	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOIPEFHO_02360	6.4e-54	-	-	-	-	-	-	-	-
HOIPEFHO_02361	6.26e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HOIPEFHO_02362	3.52e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOIPEFHO_02363	4.03e-81	-	-	-	S	-	-	-	CHY zinc finger
HOIPEFHO_02364	1.05e-282	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOIPEFHO_02365	0.0	ybeC	-	-	E	-	-	-	amino acid
HOIPEFHO_02366	4.29e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOIPEFHO_02367	2.43e-54	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HOIPEFHO_02368	1.3e-91	-	-	-	-	-	-	-	-
HOIPEFHO_02369	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HOIPEFHO_02370	2.83e-114	-	-	-	-	-	-	-	-
HOIPEFHO_02371	1.64e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOIPEFHO_02372	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOIPEFHO_02373	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOIPEFHO_02374	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOIPEFHO_02375	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HOIPEFHO_02376	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOIPEFHO_02377	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HOIPEFHO_02378	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HOIPEFHO_02379	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOIPEFHO_02380	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HOIPEFHO_02381	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOIPEFHO_02382	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HOIPEFHO_02383	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HOIPEFHO_02384	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOIPEFHO_02385	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOIPEFHO_02386	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HOIPEFHO_02387	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HOIPEFHO_02388	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOIPEFHO_02389	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HOIPEFHO_02390	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HOIPEFHO_02391	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HOIPEFHO_02392	2.74e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HOIPEFHO_02393	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HOIPEFHO_02394	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HOIPEFHO_02395	1.32e-92	-	-	-	-	-	-	-	-
HOIPEFHO_02396	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_02397	8.96e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HOIPEFHO_02398	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HOIPEFHO_02399	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HOIPEFHO_02400	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HOIPEFHO_02401	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HOIPEFHO_02402	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOIPEFHO_02403	1.8e-222	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HOIPEFHO_02404	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HOIPEFHO_02405	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HOIPEFHO_02406	3e-105	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HOIPEFHO_02407	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HOIPEFHO_02408	3.73e-112	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HOIPEFHO_02410	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HOIPEFHO_02411	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOIPEFHO_02412	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOIPEFHO_02413	1.66e-150	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOIPEFHO_02414	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HOIPEFHO_02415	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HOIPEFHO_02416	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HOIPEFHO_02417	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HOIPEFHO_02418	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HOIPEFHO_02419	1.04e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOIPEFHO_02420	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HOIPEFHO_02421	1.11e-84	-	-	-	-	-	-	-	-
HOIPEFHO_02422	6.61e-77	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_02423	6.83e-99	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HOIPEFHO_02424	1.56e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02425	9.58e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HOIPEFHO_02426	5.26e-96	-	-	-	-	-	-	-	-
HOIPEFHO_02427	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_02428	5.64e-46	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HOIPEFHO_02429	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOIPEFHO_02430	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HOIPEFHO_02431	2.09e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOIPEFHO_02432	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOIPEFHO_02433	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIPEFHO_02434	1.93e-76	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIPEFHO_02435	2.87e-172	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIPEFHO_02436	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HOIPEFHO_02437	4.66e-197	nanK	-	-	GK	-	-	-	ROK family
HOIPEFHO_02438	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HOIPEFHO_02439	1.01e-157	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HOIPEFHO_02440	2.28e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HOIPEFHO_02441	9.93e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HOIPEFHO_02442	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HOIPEFHO_02443	1.06e-16	-	-	-	-	-	-	-	-
HOIPEFHO_02444	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HOIPEFHO_02445	8.48e-37	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HOIPEFHO_02446	4.29e-316	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HOIPEFHO_02447	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HOIPEFHO_02448	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HOIPEFHO_02449	9.31e-213	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HOIPEFHO_02450	9.62e-19	-	-	-	-	-	-	-	-
HOIPEFHO_02451	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HOIPEFHO_02452	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HOIPEFHO_02454	3.24e-188	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HOIPEFHO_02455	3.4e-58	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_02456	4.68e-197	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_02457	1.66e-128	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_02458	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02459	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_02460	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HOIPEFHO_02461	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HOIPEFHO_02462	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HOIPEFHO_02463	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HOIPEFHO_02464	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HOIPEFHO_02465	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HOIPEFHO_02466	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HOIPEFHO_02467	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HOIPEFHO_02468	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOIPEFHO_02469	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HOIPEFHO_02470	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HOIPEFHO_02471	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HOIPEFHO_02472	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HOIPEFHO_02473	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HOIPEFHO_02474	8.69e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HOIPEFHO_02475	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_02476	1.64e-202	degV1	-	-	S	-	-	-	DegV family
HOIPEFHO_02477	2.79e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOIPEFHO_02478	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HOIPEFHO_02479	1.36e-105	-	-	-	S	-	-	-	ASCH
HOIPEFHO_02480	4.35e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HOIPEFHO_02481	1.67e-220	-	-	-	K	-	-	-	WYL domain
HOIPEFHO_02482	1.63e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOIPEFHO_02483	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HOIPEFHO_02484	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HOIPEFHO_02485	2.84e-81	-	-	-	S	-	-	-	Protein of unknown function
HOIPEFHO_02486	7.1e-194	-	-	-	EG	-	-	-	EamA-like transporter family
HOIPEFHO_02487	4.78e-153	-	-	-	S	-	-	-	DJ-1/PfpI family
HOIPEFHO_02488	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HOIPEFHO_02489	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_02490	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOIPEFHO_02491	6.41e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_02492	8.04e-128	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HOIPEFHO_02493	3.48e-44	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HOIPEFHO_02494	5.69e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HOIPEFHO_02495	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_02496	9.16e-209	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_02497	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02498	1.11e-217	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIPEFHO_02499	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIPEFHO_02500	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOIPEFHO_02501	8.96e-196	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HOIPEFHO_02502	7.57e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02503	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HOIPEFHO_02504	1.33e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
HOIPEFHO_02505	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HOIPEFHO_02506	2.01e-243	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HOIPEFHO_02507	1.66e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02508	3.27e-170	-	-	-	S	-	-	-	KR domain
HOIPEFHO_02509	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HOIPEFHO_02510	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HOIPEFHO_02511	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOIPEFHO_02512	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HOIPEFHO_02513	6.24e-215	-	-	-	GM	-	-	-	NmrA-like family
HOIPEFHO_02514	1.46e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02515	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HOIPEFHO_02516	3.81e-172	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HOIPEFHO_02517	6.78e-34	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HOIPEFHO_02518	3.47e-78	-	-	-	M	-	-	-	Collagen binding domain
HOIPEFHO_02519	0.0	-	-	-	I	-	-	-	acetylesterase activity
HOIPEFHO_02520	2.35e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HOIPEFHO_02521	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HOIPEFHO_02522	4.29e-50	-	-	-	-	-	-	-	-
HOIPEFHO_02524	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
HOIPEFHO_02525	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HOIPEFHO_02526	2.19e-270	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HOIPEFHO_02527	1.09e-65	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HOIPEFHO_02528	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HOIPEFHO_02529	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_02530	2.99e-133	-	-	-	-	-	-	-	-
HOIPEFHO_02531	7.16e-30	-	-	-	-	-	-	-	-
HOIPEFHO_02532	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOIPEFHO_02533	3.08e-241	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOIPEFHO_02534	6.98e-95	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOIPEFHO_02535	1.56e-108	-	-	-	-	-	-	-	-
HOIPEFHO_02536	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HOIPEFHO_02537	7.74e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOIPEFHO_02538	1.63e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HOIPEFHO_02539	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HOIPEFHO_02540	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HOIPEFHO_02541	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HOIPEFHO_02542	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_02543	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HOIPEFHO_02544	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOIPEFHO_02545	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HOIPEFHO_02546	2.83e-297	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HOIPEFHO_02547	7.97e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOIPEFHO_02548	9.48e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HOIPEFHO_02549	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HOIPEFHO_02550	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HOIPEFHO_02551	3.4e-16	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HOIPEFHO_02552	1.52e-129	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HOIPEFHO_02553	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HOIPEFHO_02554	2.62e-281	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOIPEFHO_02555	1.78e-29	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HOIPEFHO_02556	1.07e-123	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HOIPEFHO_02557	1.24e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOIPEFHO_02558	1.34e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_02559	4.19e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HOIPEFHO_02560	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HOIPEFHO_02561	3.01e-124	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HOIPEFHO_02562	2.06e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HOIPEFHO_02566	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_02567	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_02568	1.85e-49	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_02569	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_02571	2.46e-247	-	-	-	C	-	-	-	Aldo/keto reductase family
HOIPEFHO_02572	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HOIPEFHO_02573	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOIPEFHO_02574	5.29e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HOIPEFHO_02575	2.31e-79	-	-	-	-	-	-	-	-
HOIPEFHO_02576	1.02e-161	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HOIPEFHO_02577	8.17e-122	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HOIPEFHO_02578	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HOIPEFHO_02579	1.28e-45	-	-	-	-	-	-	-	-
HOIPEFHO_02580	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HOIPEFHO_02581	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HOIPEFHO_02582	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HOIPEFHO_02583	1.51e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_02584	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HOIPEFHO_02585	4.14e-110	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HOIPEFHO_02586	1.02e-13	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HOIPEFHO_02587	2.81e-64	-	-	-	-	-	-	-	-
HOIPEFHO_02588	9.76e-50	-	-	-	-	-	-	-	-
HOIPEFHO_02589	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HOIPEFHO_02590	4.86e-111	-	-	-	-	-	-	-	-
HOIPEFHO_02592	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOIPEFHO_02593	1.84e-140	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOIPEFHO_02594	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOIPEFHO_02596	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02597	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02598	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HOIPEFHO_02599	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HOIPEFHO_02600	1.37e-99	yphH	-	-	S	-	-	-	Cupin domain
HOIPEFHO_02601	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HOIPEFHO_02602	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_02603	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOIPEFHO_02604	5.77e-213	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02605	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HOIPEFHO_02606	9.92e-88	-	-	-	M	-	-	-	LysM domain
HOIPEFHO_02608	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOIPEFHO_02609	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HOIPEFHO_02610	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HOIPEFHO_02611	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HOIPEFHO_02612	7.96e-127	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOIPEFHO_02613	2.33e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HOIPEFHO_02614	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOIPEFHO_02615	3.85e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HOIPEFHO_02616	3.04e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOIPEFHO_02617	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HOIPEFHO_02618	3.49e-198	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOIPEFHO_02619	7.4e-154	-	-	-	S	-	-	-	Membrane
HOIPEFHO_02620	8.02e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIPEFHO_02621	1.45e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HOIPEFHO_02622	8.13e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HOIPEFHO_02623	2.27e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HOIPEFHO_02624	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02625	4.88e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02626	5.35e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HOIPEFHO_02627	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOIPEFHO_02628	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_02629	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HOIPEFHO_02630	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HOIPEFHO_02631	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HOIPEFHO_02632	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HOIPEFHO_02633	1.27e-143	-	-	-	-	-	-	-	-
HOIPEFHO_02634	3.47e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOIPEFHO_02635	8.02e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HOIPEFHO_02636	2.05e-55	-	-	-	-	-	-	-	-
HOIPEFHO_02637	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HOIPEFHO_02638	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HOIPEFHO_02639	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HOIPEFHO_02640	7.27e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HOIPEFHO_02641	1.12e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOIPEFHO_02642	1.32e-170	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HOIPEFHO_02643	1.98e-155	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_02644	8.47e-273	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HOIPEFHO_02645	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HOIPEFHO_02646	5.62e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HOIPEFHO_02647	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HOIPEFHO_02648	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HOIPEFHO_02649	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HOIPEFHO_02650	1.49e-63	-	-	-	-	-	-	-	-
HOIPEFHO_02651	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HOIPEFHO_02652	4.5e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOIPEFHO_02653	2.87e-56	-	-	-	-	-	-	-	-
HOIPEFHO_02654	3.35e-75	-	-	-	-	-	-	-	-
HOIPEFHO_02655	4.62e-309	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_02656	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOIPEFHO_02657	2.42e-65	-	-	-	-	-	-	-	-
HOIPEFHO_02658	1.9e-165	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HOIPEFHO_02659	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
HOIPEFHO_02660	8.98e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOIPEFHO_02661	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_02662	1.55e-55	-	-	-	-	-	-	-	-
HOIPEFHO_02663	4.48e-52	-	-	-	-	-	-	-	-
HOIPEFHO_02664	1.15e-152	-	-	-	-	-	-	-	-
HOIPEFHO_02665	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HOIPEFHO_02666	2.03e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02667	4.24e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02668	1.96e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOIPEFHO_02669	8.83e-06	-	-	-	-	-	-	-	-
HOIPEFHO_02670	2.21e-84	-	-	-	D	-	-	-	AAA domain
HOIPEFHO_02671	5.3e-49	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOIPEFHO_02672	1.36e-145	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HOIPEFHO_02673	1.54e-51	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HOIPEFHO_02674	2.23e-101	-	-	-	L	-	-	-	manually curated
HOIPEFHO_02675	6.17e-61	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HOIPEFHO_02676	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HOIPEFHO_02677	7.66e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02678	7.03e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HOIPEFHO_02679	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HOIPEFHO_02680	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HOIPEFHO_02681	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HOIPEFHO_02682	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HOIPEFHO_02683	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HOIPEFHO_02684	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOIPEFHO_02685	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HOIPEFHO_02686	9.2e-62	-	-	-	-	-	-	-	-
HOIPEFHO_02687	3.9e-105	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIPEFHO_02688	2.65e-139	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HOIPEFHO_02689	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HOIPEFHO_02690	2.61e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOIPEFHO_02691	1.06e-138	-	-	-	L	-	-	-	Resolvase, N terminal domain
HOIPEFHO_02692	6.35e-147	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOIPEFHO_02693	3.29e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HOIPEFHO_02694	1.26e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HOIPEFHO_02695	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOIPEFHO_02696	7.07e-106	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HOIPEFHO_02697	5.16e-09	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HOIPEFHO_02698	1.14e-76	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOIPEFHO_02699	5.82e-124	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HOIPEFHO_02700	1.49e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_02701	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HOIPEFHO_02702	4.73e-55	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HOIPEFHO_02703	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_02704	1.47e-83	-	-	-	-	-	-	-	-
HOIPEFHO_02705	2.16e-303	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HOIPEFHO_02706	2.38e-156	-	-	-	-	-	-	-	-
HOIPEFHO_02707	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HOIPEFHO_02708	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HOIPEFHO_02709	2.24e-246	-	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_02710	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HOIPEFHO_02711	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HOIPEFHO_02712	4.03e-239	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOIPEFHO_02713	1.28e-178	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HOIPEFHO_02714	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HOIPEFHO_02715	1.37e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HOIPEFHO_02716	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HOIPEFHO_02717	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HOIPEFHO_02718	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HOIPEFHO_02719	2.4e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HOIPEFHO_02720	1.1e-275	-	-	-	-	-	-	-	-
HOIPEFHO_02721	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_02722	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02723	3.1e-288	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HOIPEFHO_02724	4.9e-208	yhxD	-	-	IQ	-	-	-	KR domain
HOIPEFHO_02726	1.97e-92	-	-	-	-	-	-	-	-
HOIPEFHO_02727	4.1e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOIPEFHO_02728	0.0	-	-	-	E	-	-	-	Amino Acid
HOIPEFHO_02729	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HOIPEFHO_02730	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HOIPEFHO_02731	2.77e-271	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HOIPEFHO_02732	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HOIPEFHO_02733	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HOIPEFHO_02734	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HOIPEFHO_02735	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HOIPEFHO_02736	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HOIPEFHO_02737	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HOIPEFHO_02738	2.06e-287	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HOIPEFHO_02739	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_02740	2.69e-99	-	-	-	-	-	-	-	-
HOIPEFHO_02741	7.3e-246	-	-	-	S	-	-	-	Cell surface protein
HOIPEFHO_02742	7.02e-136	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_02743	1.09e-224	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HOIPEFHO_02744	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HOIPEFHO_02745	3.33e-149	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HOIPEFHO_02746	5.94e-69	-	-	-	Q	-	-	-	Methyltransferase
HOIPEFHO_02747	4.25e-26	-	-	-	Q	-	-	-	Methyltransferase
HOIPEFHO_02748	2.38e-176	repA	-	-	S	-	-	-	Replication initiator protein A
HOIPEFHO_02750	8.87e-173	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HOIPEFHO_02751	2.66e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02773	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HOIPEFHO_02774	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HOIPEFHO_02775	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HOIPEFHO_02776	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HOIPEFHO_02777	3.06e-262	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HOIPEFHO_02778	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HOIPEFHO_02779	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HOIPEFHO_02780	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HOIPEFHO_02781	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOIPEFHO_02782	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOIPEFHO_02783	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HOIPEFHO_02784	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HOIPEFHO_02785	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HOIPEFHO_02786	7.81e-263	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HOIPEFHO_02787	2.51e-150	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HOIPEFHO_02788	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HOIPEFHO_02789	7.67e-167	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HOIPEFHO_02790	5.94e-49	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HOIPEFHO_02791	2.97e-234	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HOIPEFHO_02792	4.63e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HOIPEFHO_02793	1.85e-125	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HOIPEFHO_02796	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HOIPEFHO_02797	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOIPEFHO_02798	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HOIPEFHO_02799	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HOIPEFHO_02800	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HOIPEFHO_02801	3.06e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HOIPEFHO_02802	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HOIPEFHO_02803	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOIPEFHO_02804	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HOIPEFHO_02805	4.58e-228	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HOIPEFHO_02806	1.38e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HOIPEFHO_02809	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOIPEFHO_02811	7.66e-106	-	-	-	-	-	-	-	-
HOIPEFHO_02812	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HOIPEFHO_02813	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HOIPEFHO_02814	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HOIPEFHO_02815	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOIPEFHO_02816	3.79e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOIPEFHO_02817	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOIPEFHO_02818	8.31e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HOIPEFHO_02819	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HOIPEFHO_02820	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOIPEFHO_02821	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HOIPEFHO_02822	5.6e-41	-	-	-	-	-	-	-	-
HOIPEFHO_02823	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HOIPEFHO_02824	2.92e-131	-	-	-	L	-	-	-	Integrase
HOIPEFHO_02825	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HOIPEFHO_02826	5.43e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOIPEFHO_02827	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOIPEFHO_02828	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIPEFHO_02829	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIPEFHO_02830	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_02831	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HOIPEFHO_02832	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOIPEFHO_02833	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HOIPEFHO_02834	3.51e-251	-	-	-	M	-	-	-	MucBP domain
HOIPEFHO_02835	0.0	-	-	-	-	-	-	-	-
HOIPEFHO_02836	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HOIPEFHO_02837	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HOIPEFHO_02838	1.3e-77	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HOIPEFHO_02839	3.57e-116	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HOIPEFHO_02840	5.58e-305	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HOIPEFHO_02841	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HOIPEFHO_02842	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HOIPEFHO_02843	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HOIPEFHO_02844	1.73e-178	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HOIPEFHO_02845	5.09e-51	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HOIPEFHO_02846	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HOIPEFHO_02847	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HOIPEFHO_02848	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HOIPEFHO_02849	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HOIPEFHO_02850	3.29e-169	-	-	-	-	-	-	-	-
HOIPEFHO_02851	8.02e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HOIPEFHO_02852	8.39e-38	-	-	-	-	-	-	-	-
HOIPEFHO_02853	1.95e-41	-	-	-	-	-	-	-	-
HOIPEFHO_02854	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HOIPEFHO_02855	9.02e-70	-	-	-	-	-	-	-	-
HOIPEFHO_02856	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HOIPEFHO_02857	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HOIPEFHO_02858	2.18e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_02859	0.0	-	-	-	M	-	-	-	domain protein
HOIPEFHO_02860	5.52e-139	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOIPEFHO_02861	9.83e-189	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HOIPEFHO_02862	1.28e-253	cps3I	-	-	G	-	-	-	Acyltransferase family
HOIPEFHO_02863	9.47e-261	cps3H	-	-	-	-	-	-	-
HOIPEFHO_02864	1.11e-205	cps3F	-	-	-	-	-	-	-
HOIPEFHO_02865	2.8e-143	cps3E	-	-	-	-	-	-	-
HOIPEFHO_02866	1.83e-249	cps3D	-	-	-	-	-	-	-
HOIPEFHO_02867	4.67e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HOIPEFHO_02868	5.21e-226	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HOIPEFHO_02869	2.1e-217	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HOIPEFHO_02870	7.72e-35	-	-	-	S	-	-	-	Barstar (barnase inhibitor)
HOIPEFHO_02871	8.72e-73	-	-	-	S	-	-	-	Immunity protein 63
HOIPEFHO_02873	2.32e-152	-	-	-	-	-	-	-	-
HOIPEFHO_02875	4.82e-56	-	-	-	S	-	-	-	ankyrin repeats
HOIPEFHO_02877	2.15e-174	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOIPEFHO_02878	3.47e-142	-	-	-	-	-	-	-	-
HOIPEFHO_02879	1.08e-172	-	-	-	-	-	-	-	-
HOIPEFHO_02880	9.17e-41	-	-	-	-	-	-	-	-
HOIPEFHO_02881	3.07e-48	-	-	-	-	-	-	-	-
HOIPEFHO_02882	2.61e-152	-	-	-	-	-	-	-	-
HOIPEFHO_02884	3.23e-58	-	-	-	-	-	-	-	-
HOIPEFHO_02885	1.79e-172	-	-	-	M	ko:K21493	-	ko00000,ko01000,ko02048	self proteolysis
HOIPEFHO_02886	7.28e-175	-	-	-	M	-	-	-	domain protein
HOIPEFHO_02887	1e-28	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HOIPEFHO_02888	2.34e-105	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HOIPEFHO_02889	5.71e-57	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HOIPEFHO_02890	1.47e-167	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HOIPEFHO_02891	2.08e-218	-	-	-	-	-	-	-	-
HOIPEFHO_02892	1.54e-159	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HOIPEFHO_02893	1.47e-166	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HOIPEFHO_02894	8.38e-160	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HOIPEFHO_02895	1.33e-226	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HOIPEFHO_02896	1.69e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HOIPEFHO_02897	6.79e-163	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HOIPEFHO_02898	8.87e-168	epsB	-	-	M	-	-	-	biosynthesis protein
HOIPEFHO_02899	3.69e-130	-	-	-	L	-	-	-	Integrase
HOIPEFHO_02900	3.94e-106	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOIPEFHO_02901	7.77e-90	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOIPEFHO_02902	5.05e-130	-	-	-	M	-	-	-	Parallel beta-helix repeats
HOIPEFHO_02903	1.33e-82	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HOIPEFHO_02904	2.02e-214	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HOIPEFHO_02905	6.89e-68	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HOIPEFHO_02906	1.4e-62	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIPEFHO_02907	2e-117	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HOIPEFHO_02908	2.34e-99	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HOIPEFHO_02909	1.43e-28	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HOIPEFHO_02910	7.12e-09	-	-	-	V	-	-	-	Beta-lactamase
HOIPEFHO_02911	2.23e-10	cap5B	-	-	D	-	-	-	NUBPL iron-transfer P-loop NTPase
HOIPEFHO_02913	6.08e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HOIPEFHO_02914	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOIPEFHO_02915	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HOIPEFHO_02916	2.74e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HOIPEFHO_02917	2.41e-106	pbpX	-	-	V	-	-	-	Beta-lactamase
HOIPEFHO_02918	4e-157	pbpX	-	-	V	-	-	-	Beta-lactamase
HOIPEFHO_02919	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HOIPEFHO_02920	1.18e-138	-	-	-	-	-	-	-	-
HOIPEFHO_02921	7.62e-97	-	-	-	-	-	-	-	-
HOIPEFHO_02923	1.59e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_02924	5e-310	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIPEFHO_02925	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HOIPEFHO_02927	2.34e-315	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HOIPEFHO_02928	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HOIPEFHO_02929	2.54e-42	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HOIPEFHO_02930	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HOIPEFHO_02931	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HOIPEFHO_02932	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOIPEFHO_02933	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOIPEFHO_02934	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOIPEFHO_02935	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
HOIPEFHO_02937	4.03e-170	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HOIPEFHO_02939	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HOIPEFHO_02940	3.69e-230	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HOIPEFHO_02941	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HOIPEFHO_02942	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HOIPEFHO_02943	1.11e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HOIPEFHO_02944	1.19e-226	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HOIPEFHO_02945	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HOIPEFHO_02946	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HOIPEFHO_02947	1.57e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HOIPEFHO_02948	4.42e-36	-	-	-	-	-	-	-	-
HOIPEFHO_02949	2.27e-53	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HOIPEFHO_02950	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HOIPEFHO_02951	9.85e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOIPEFHO_02952	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_02953	1.19e-108	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOIPEFHO_02954	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOIPEFHO_02955	8.83e-93	-	-	-	K	-	-	-	MarR family
HOIPEFHO_02956	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HOIPEFHO_02957	6.26e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_02958	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HOIPEFHO_02959	4.87e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HOIPEFHO_02960	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HOIPEFHO_02961	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HOIPEFHO_02962	7.04e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HOIPEFHO_02963	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02964	4.45e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOIPEFHO_02965	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HOIPEFHO_02966	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_02968	1.28e-54	-	-	-	-	-	-	-	-
HOIPEFHO_02969	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIPEFHO_02970	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOIPEFHO_02971	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HOIPEFHO_02972	1.01e-188	-	-	-	-	-	-	-	-
HOIPEFHO_02973	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HOIPEFHO_02974	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HOIPEFHO_02975	9.98e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HOIPEFHO_02976	1.48e-27	-	-	-	-	-	-	-	-
HOIPEFHO_02977	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HOIPEFHO_02978	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HOIPEFHO_02979	6.12e-115	-	-	-	-	-	-	-	-
HOIPEFHO_02980	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOIPEFHO_02981	3.8e-61	-	-	-	-	-	-	-	-
HOIPEFHO_02982	7.76e-83	-	-	-	O	-	-	-	OsmC-like protein
HOIPEFHO_02983	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HOIPEFHO_02984	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HOIPEFHO_02985	5.01e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOIPEFHO_02986	1.83e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HOIPEFHO_02987	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_02988	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HOIPEFHO_02989	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOIPEFHO_02990	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HOIPEFHO_02991	1.36e-27	-	-	-	-	-	-	-	-
HOIPEFHO_02992	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HOIPEFHO_02993	7.8e-196	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HOIPEFHO_02994	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HOIPEFHO_02995	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HOIPEFHO_02996	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HOIPEFHO_02997	1.69e-312	-	-	-	EGP	-	-	-	Major Facilitator
HOIPEFHO_02998	1.41e-115	-	-	-	V	-	-	-	VanZ like family
HOIPEFHO_02999	3.88e-46	-	-	-	-	-	-	-	-
HOIPEFHO_03000	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HOIPEFHO_03002	2.6e-185	-	-	-	-	-	-	-	-
HOIPEFHO_03003	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HOIPEFHO_03004	3.51e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HOIPEFHO_03005	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HOIPEFHO_03006	2.49e-95	-	-	-	-	-	-	-	-
HOIPEFHO_03007	3.38e-70	-	-	-	-	-	-	-	-
HOIPEFHO_03008	1.46e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HOIPEFHO_03009	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOIPEFHO_03010	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HOIPEFHO_03011	5.44e-159	-	-	-	T	-	-	-	EAL domain
HOIPEFHO_03012	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOIPEFHO_03013	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOIPEFHO_03014	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HOIPEFHO_03015	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOIPEFHO_03016	7.74e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HOIPEFHO_03017	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOIPEFHO_03018	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOIPEFHO_03019	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HOIPEFHO_03020	1.79e-212	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HOIPEFHO_03021	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HOIPEFHO_03022	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HOIPEFHO_03023	4.88e-112	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_03024	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HOIPEFHO_03025	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HOIPEFHO_03026	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOIPEFHO_03027	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOIPEFHO_03028	2.29e-136	-	-	-	-	-	-	-	-
HOIPEFHO_03029	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOIPEFHO_03030	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOIPEFHO_03031	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HOIPEFHO_03032	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOIPEFHO_03033	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HOIPEFHO_03034	3.83e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HOIPEFHO_03035	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HOIPEFHO_03036	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOIPEFHO_03037	4.68e-167	-	-	-	-	-	-	-	-
HOIPEFHO_03038	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOIPEFHO_03039	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOIPEFHO_03040	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HOIPEFHO_03041	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOIPEFHO_03042	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HOIPEFHO_03043	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HOIPEFHO_03045	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOIPEFHO_03046	5.18e-224	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIPEFHO_03047	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HOIPEFHO_03048	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HOIPEFHO_03049	5.32e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HOIPEFHO_03050	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HOIPEFHO_03051	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HOIPEFHO_03052	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HOIPEFHO_03053	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOIPEFHO_03054	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOIPEFHO_03055	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOIPEFHO_03056	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOIPEFHO_03057	3.17e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HOIPEFHO_03058	4.19e-265	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HOIPEFHO_03059	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HOIPEFHO_03060	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HOIPEFHO_03061	6.88e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HOIPEFHO_03062	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HOIPEFHO_03063	2.07e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HOIPEFHO_03064	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HOIPEFHO_03065	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOIPEFHO_03066	0.0	nox	-	-	C	-	-	-	NADH oxidase
HOIPEFHO_03067	3.69e-159	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HOIPEFHO_03068	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HOIPEFHO_03069	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HOIPEFHO_03070	2.55e-212	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOIPEFHO_03071	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOIPEFHO_03072	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HOIPEFHO_03073	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HOIPEFHO_03074	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HOIPEFHO_03075	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOIPEFHO_03076	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOIPEFHO_03077	2.91e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HOIPEFHO_03078	1.83e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HOIPEFHO_03079	3.99e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HOIPEFHO_03080	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOIPEFHO_03081	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HOIPEFHO_03082	3.68e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HOIPEFHO_03083	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOIPEFHO_03084	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOIPEFHO_03085	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOIPEFHO_03086	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HOIPEFHO_03087	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HOIPEFHO_03088	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HOIPEFHO_03089	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HOIPEFHO_03090	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HOIPEFHO_03091	0.0	ydaO	-	-	E	-	-	-	amino acid
HOIPEFHO_03092	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOIPEFHO_03093	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOIPEFHO_03094	4.81e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOIPEFHO_03095	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOIPEFHO_03096	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HOIPEFHO_03097	2.32e-301	-	-	-	S	-	-	-	module of peptide synthetase
HOIPEFHO_03098	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOIPEFHO_03099	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HOIPEFHO_03100	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HOIPEFHO_03101	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HOIPEFHO_03102	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HOIPEFHO_03103	2.34e-139	-	-	-	M	-	-	-	domain protein
HOIPEFHO_03104	5.43e-220	-	-	-	M	-	-	-	domain protein
HOIPEFHO_03105	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HOIPEFHO_03106	1.26e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HOIPEFHO_03107	1.45e-46	-	-	-	-	-	-	-	-
HOIPEFHO_03108	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOIPEFHO_03109	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HOIPEFHO_03110	2.49e-190	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIPEFHO_03111	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HOIPEFHO_03112	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HOIPEFHO_03113	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HOIPEFHO_03114	7.5e-283	ysaA	-	-	V	-	-	-	RDD family
HOIPEFHO_03115	3.2e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HOIPEFHO_03116	4.44e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HOIPEFHO_03117	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HOIPEFHO_03118	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOIPEFHO_03119	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HOIPEFHO_03120	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOIPEFHO_03121	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HOIPEFHO_03122	1.81e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOIPEFHO_03123	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOIPEFHO_03124	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HOIPEFHO_03125	5.72e-81	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOIPEFHO_03126	3.52e-160	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOIPEFHO_03127	4.99e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOIPEFHO_03128	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HOIPEFHO_03129	3.87e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase