ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NHGFBNON_00001 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NHGFBNON_00002 5.17e-219 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NHGFBNON_00003 2.14e-178 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NHGFBNON_00004 2.38e-99 - - - - - - - -
NHGFBNON_00005 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NHGFBNON_00006 5.67e-179 - - - - - - - -
NHGFBNON_00007 4.07e-05 - - - - - - - -
NHGFBNON_00008 1.62e-185 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NHGFBNON_00009 1.67e-54 - - - - - - - -
NHGFBNON_00010 7.41e-167 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_00011 8.38e-193 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NHGFBNON_00012 1.51e-234 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NHGFBNON_00013 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
NHGFBNON_00014 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
NHGFBNON_00015 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
NHGFBNON_00016 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NHGFBNON_00017 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
NHGFBNON_00018 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHGFBNON_00019 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
NHGFBNON_00020 6.09e-228 - - - C - - - Zinc-binding dehydrogenase
NHGFBNON_00021 1.87e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHGFBNON_00022 8.33e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NHGFBNON_00023 7.15e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHGFBNON_00024 9.14e-265 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NHGFBNON_00025 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NHGFBNON_00026 0.0 - - - L - - - HIRAN domain
NHGFBNON_00027 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NHGFBNON_00028 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NHGFBNON_00029 3.8e-161 - - - - - - - -
NHGFBNON_00030 5.08e-192 - - - I - - - Alpha/beta hydrolase family
NHGFBNON_00031 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NHGFBNON_00032 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NHGFBNON_00033 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NHGFBNON_00034 1.27e-98 - - - K - - - Transcriptional regulator
NHGFBNON_00035 2.31e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHGFBNON_00036 2.14e-39 - - - S - - - Protein of unknown function (DUF3021)
NHGFBNON_00037 7.39e-87 - - - K - - - LytTr DNA-binding domain
NHGFBNON_00038 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NHGFBNON_00039 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHGFBNON_00040 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NHGFBNON_00042 1.34e-198 morA - - S - - - reductase
NHGFBNON_00043 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
NHGFBNON_00044 4.54e-105 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
NHGFBNON_00045 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NHGFBNON_00046 4.03e-132 - - - - - - - -
NHGFBNON_00047 0.0 - - - - - - - -
NHGFBNON_00048 7.26e-265 - - - C - - - Oxidoreductase
NHGFBNON_00049 7.71e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NHGFBNON_00050 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00051 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NHGFBNON_00053 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NHGFBNON_00054 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
NHGFBNON_00055 3.14e-182 - - - - - - - -
NHGFBNON_00056 1.29e-190 - - - - - - - -
NHGFBNON_00057 3.37e-115 - - - - - - - -
NHGFBNON_00058 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
NHGFBNON_00059 4.24e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_00060 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NHGFBNON_00061 1.09e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_00062 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
NHGFBNON_00063 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
NHGFBNON_00065 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00066 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NHGFBNON_00067 3.88e-239 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NHGFBNON_00068 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NHGFBNON_00069 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NHGFBNON_00070 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHGFBNON_00071 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NHGFBNON_00072 1.06e-230 yvdE - - K - - - helix_turn _helix lactose operon repressor
NHGFBNON_00073 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NHGFBNON_00074 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHGFBNON_00075 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_00076 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_00077 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
NHGFBNON_00078 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
NHGFBNON_00079 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHGFBNON_00080 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NHGFBNON_00081 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
NHGFBNON_00082 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
NHGFBNON_00083 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NHGFBNON_00084 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NHGFBNON_00085 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_00086 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NHGFBNON_00087 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NHGFBNON_00088 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NHGFBNON_00089 9.51e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NHGFBNON_00090 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NHGFBNON_00091 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NHGFBNON_00092 5.99e-213 mleR - - K - - - LysR substrate binding domain
NHGFBNON_00093 0.0 - - - M - - - domain protein
NHGFBNON_00095 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NHGFBNON_00096 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NHGFBNON_00097 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NHGFBNON_00098 3.22e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NHGFBNON_00099 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGFBNON_00100 7.18e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHGFBNON_00101 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
NHGFBNON_00102 7.12e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NHGFBNON_00103 6.33e-46 - - - - - - - -
NHGFBNON_00104 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
NHGFBNON_00105 6.48e-210 fbpA - - K - - - Domain of unknown function (DUF814)
NHGFBNON_00106 1.5e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHGFBNON_00107 3.81e-18 - - - - - - - -
NHGFBNON_00108 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHGFBNON_00109 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHGFBNON_00110 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
NHGFBNON_00111 8.68e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NHGFBNON_00112 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHGFBNON_00113 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
NHGFBNON_00114 2.28e-114 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NHGFBNON_00115 2.16e-201 dkgB - - S - - - reductase
NHGFBNON_00116 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHGFBNON_00117 1.2e-91 - - - - - - - -
NHGFBNON_00118 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHGFBNON_00120 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHGFBNON_00121 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_00122 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NHGFBNON_00123 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_00124 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NHGFBNON_00125 1.21e-111 - - - - - - - -
NHGFBNON_00126 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NHGFBNON_00127 2.75e-52 - - - - - - - -
NHGFBNON_00128 1.22e-125 - - - - - - - -
NHGFBNON_00129 2.98e-90 - - - - - - - -
NHGFBNON_00130 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NHGFBNON_00131 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NHGFBNON_00132 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NHGFBNON_00133 7.42e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
NHGFBNON_00134 1e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NHGFBNON_00135 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NHGFBNON_00136 3.89e-202 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NHGFBNON_00137 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NHGFBNON_00138 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
NHGFBNON_00139 6.35e-56 - - - - - - - -
NHGFBNON_00140 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NHGFBNON_00141 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NHGFBNON_00142 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_00143 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NHGFBNON_00144 2.13e-184 - - - - - - - -
NHGFBNON_00145 1.78e-128 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NHGFBNON_00146 7.84e-92 - - - - - - - -
NHGFBNON_00147 8.9e-96 ywnA - - K - - - Transcriptional regulator
NHGFBNON_00148 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00149 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NHGFBNON_00150 1.15e-152 - - - - - - - -
NHGFBNON_00151 2.92e-57 - - - - - - - -
NHGFBNON_00152 1.55e-55 - - - - - - - -
NHGFBNON_00153 5.98e-103 ydiC - - EGP - - - Major Facilitator
NHGFBNON_00154 7.09e-156 ydiC - - EGP - - - Major Facilitator
NHGFBNON_00155 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_00156 1.82e-316 hpk2 - - T - - - Histidine kinase
NHGFBNON_00157 3.28e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
NHGFBNON_00158 2.42e-65 - - - - - - - -
NHGFBNON_00159 1.13e-166 yidA - - K - - - Helix-turn-helix domain, rpiR family
NHGFBNON_00160 1.81e-308 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_00161 6.77e-75 - - - - - - - -
NHGFBNON_00162 2.87e-56 - - - - - - - -
NHGFBNON_00163 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NHGFBNON_00164 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NHGFBNON_00165 1.49e-63 - - - - - - - -
NHGFBNON_00166 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NHGFBNON_00167 1.17e-135 - - - K - - - transcriptional regulator
NHGFBNON_00168 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NHGFBNON_00169 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NHGFBNON_00170 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NHGFBNON_00171 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NHGFBNON_00172 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_00173 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_00174 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_00175 7.98e-80 - - - M - - - Lysin motif
NHGFBNON_00176 1.43e-82 - - - M - - - LysM domain protein
NHGFBNON_00177 1.71e-87 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
NHGFBNON_00178 6.1e-227 - - - - - - - -
NHGFBNON_00179 2.8e-169 - - - - - - - -
NHGFBNON_00180 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NHGFBNON_00181 4.8e-74 - - - - - - - -
NHGFBNON_00182 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHGFBNON_00183 7.61e-102 - - - S ko:K02348 - ko00000 GNAT family
NHGFBNON_00184 1.24e-99 - - - K - - - Transcriptional regulator
NHGFBNON_00185 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NHGFBNON_00186 6.01e-51 - - - - - - - -
NHGFBNON_00188 1.04e-35 - - - - - - - -
NHGFBNON_00189 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
NHGFBNON_00190 4.36e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_00191 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_00192 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_00193 5.09e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHGFBNON_00194 4.3e-124 - - - K - - - Cupin domain
NHGFBNON_00195 8.08e-110 - - - S - - - ASCH
NHGFBNON_00196 1.88e-111 - - - K - - - GNAT family
NHGFBNON_00197 2.14e-117 - - - K - - - acetyltransferase
NHGFBNON_00198 2.06e-30 - - - - - - - -
NHGFBNON_00199 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NHGFBNON_00200 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_00201 3.09e-243 - - - - - - - -
NHGFBNON_00202 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
NHGFBNON_00203 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NHGFBNON_00205 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
NHGFBNON_00206 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NHGFBNON_00207 7.28e-42 - - - - - - - -
NHGFBNON_00208 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHGFBNON_00209 9.1e-54 - - - - - - - -
NHGFBNON_00210 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NHGFBNON_00211 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHGFBNON_00212 1.45e-79 - - - S - - - CHY zinc finger
NHGFBNON_00213 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NHGFBNON_00214 7.98e-158 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHGFBNON_00215 4.45e-116 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_00216 1.14e-186 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHGFBNON_00217 2.25e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHGFBNON_00218 1.07e-26 - - - - - - - -
NHGFBNON_00219 1.56e-22 - - - - - - - -
NHGFBNON_00220 3.26e-24 - - - - - - - -
NHGFBNON_00221 6.58e-24 - - - - - - - -
NHGFBNON_00222 0.0 inlJ - - M - - - MucBP domain
NHGFBNON_00223 0.0 - - - D - - - nuclear chromosome segregation
NHGFBNON_00224 1.27e-109 - - - K - - - MarR family
NHGFBNON_00225 9.28e-58 - - - - - - - -
NHGFBNON_00226 1.28e-51 - - - - - - - -
NHGFBNON_00227 3.6e-289 - - - L - - - Belongs to the 'phage' integrase family
NHGFBNON_00228 2.12e-17 ansR - - K - - - Transcriptional regulator
NHGFBNON_00230 2.62e-40 - - - - - - - -
NHGFBNON_00231 1.88e-179 - - - L - - - DNA replication protein
NHGFBNON_00232 1.09e-63 - - - S - - - Phage plasmid primase P4 family
NHGFBNON_00234 1e-31 - - - - - - - -
NHGFBNON_00235 1.87e-65 - - - S - - - Head-tail joining protein
NHGFBNON_00236 1.05e-88 - - - L - - - HNH endonuclease
NHGFBNON_00237 7.73e-109 - - - L - - - overlaps another CDS with the same product name
NHGFBNON_00238 0.0 terL - - S - - - overlaps another CDS with the same product name
NHGFBNON_00239 2.13e-05 - - - - - - - -
NHGFBNON_00240 9.78e-257 - - - S - - - Phage portal protein
NHGFBNON_00241 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NHGFBNON_00244 1.62e-53 - - - S - - - Phage gp6-like head-tail connector protein
NHGFBNON_00245 7.78e-76 - - - - - - - -
NHGFBNON_00248 1.98e-40 - - - - - - - -
NHGFBNON_00250 4.54e-198 int3 - - L - - - Belongs to the 'phage' integrase family
NHGFBNON_00251 1.51e-17 int3 - - L - - - Belongs to the 'phage' integrase family
NHGFBNON_00253 2.07e-43 - - - - - - - -
NHGFBNON_00258 9.51e-48 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NHGFBNON_00260 7.78e-46 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHGFBNON_00265 1.65e-101 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
NHGFBNON_00266 1.31e-202 - - - J - - - Domain of unknown function (DUF4041)
NHGFBNON_00267 4.71e-98 - - - E - - - IrrE N-terminal-like domain
NHGFBNON_00268 1.32e-80 - - - K - - - Helix-turn-helix domain
NHGFBNON_00269 1.2e-49 - - - K - - - Helix-turn-helix
NHGFBNON_00271 8.29e-51 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
NHGFBNON_00272 1.13e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHGFBNON_00275 7.71e-71 - - - - - - - -
NHGFBNON_00276 1.28e-102 - - - - - - - -
NHGFBNON_00278 4.3e-92 - - - - - - - -
NHGFBNON_00279 3.15e-199 - - - L ko:K07455 - ko00000,ko03400 RecT family
NHGFBNON_00280 7.45e-180 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NHGFBNON_00281 2.08e-197 - - - L - - - DnaD domain protein
NHGFBNON_00282 1.32e-66 - - - - - - - -
NHGFBNON_00283 3.18e-81 - - - - - - - -
NHGFBNON_00284 6.67e-86 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NHGFBNON_00285 5.18e-08 - - - - - - - -
NHGFBNON_00286 2.61e-105 - - - S - - - Phage transcriptional regulator, ArpU family
NHGFBNON_00289 1.92e-169 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
NHGFBNON_00290 1.06e-215 - - - - - - - -
NHGFBNON_00292 6.78e-18 - - - - - - - -
NHGFBNON_00293 5.06e-84 - - - L ko:K07474 - ko00000 Terminase small subunit
NHGFBNON_00294 1.78e-305 - - - S - - - Terminase-like family
NHGFBNON_00295 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
NHGFBNON_00296 0.0 - - - S - - - Phage Mu protein F like protein
NHGFBNON_00297 3.05e-41 - - - - - - - -
NHGFBNON_00300 6.96e-65 - - - - - - - -
NHGFBNON_00301 1.2e-221 - - - S - - - Phage major capsid protein E
NHGFBNON_00303 2.9e-68 - - - - - - - -
NHGFBNON_00304 9.63e-68 - - - - - - - -
NHGFBNON_00305 5.34e-115 - - - - - - - -
NHGFBNON_00306 3.49e-72 - - - - - - - -
NHGFBNON_00307 7.42e-102 - - - S - - - Phage tail tube protein, TTP
NHGFBNON_00308 4.97e-84 - - - - - - - -
NHGFBNON_00309 3.76e-32 - - - - - - - -
NHGFBNON_00310 0.0 - - - D - - - domain protein
NHGFBNON_00311 2.29e-81 - - - - - - - -
NHGFBNON_00312 0.0 - - - LM - - - DNA recombination
NHGFBNON_00313 5.3e-94 - - - S - - - Protein of unknown function (DUF1617)
NHGFBNON_00315 1.45e-256 - - - M - - - Glycosyl hydrolases family 25
NHGFBNON_00316 3.19e-50 - - - S - - - Haemolysin XhlA
NHGFBNON_00319 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
NHGFBNON_00320 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
NHGFBNON_00321 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00322 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NHGFBNON_00323 6.55e-183 - - - - - - - -
NHGFBNON_00324 1.35e-93 - - - - - - - -
NHGFBNON_00325 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NHGFBNON_00326 2.07e-118 - - - - - - - -
NHGFBNON_00327 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHGFBNON_00328 1.07e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHGFBNON_00329 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHGFBNON_00330 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHGFBNON_00331 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NHGFBNON_00332 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHGFBNON_00333 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NHGFBNON_00334 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHGFBNON_00335 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHGFBNON_00336 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
NHGFBNON_00337 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHGFBNON_00338 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
NHGFBNON_00339 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHGFBNON_00340 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHGFBNON_00341 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NHGFBNON_00342 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
NHGFBNON_00343 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NHGFBNON_00344 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHGFBNON_00345 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NHGFBNON_00346 7.94e-114 ykuL - - S - - - (CBS) domain
NHGFBNON_00347 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHGFBNON_00348 4.54e-287 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHGFBNON_00349 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NHGFBNON_00350 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHGFBNON_00351 4.51e-79 - - - - - - - -
NHGFBNON_00352 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_00353 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NHGFBNON_00354 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NHGFBNON_00355 1.59e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
NHGFBNON_00356 8.49e-66 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
NHGFBNON_00357 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
NHGFBNON_00358 1.19e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHGFBNON_00359 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NHGFBNON_00360 9.71e-204 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NHGFBNON_00361 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
NHGFBNON_00362 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
NHGFBNON_00363 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
NHGFBNON_00365 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NHGFBNON_00366 3.31e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHGFBNON_00367 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NHGFBNON_00368 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
NHGFBNON_00369 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NHGFBNON_00370 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
NHGFBNON_00371 1.19e-187 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHGFBNON_00372 3.3e-151 - - - S - - - Protein of unknown function (DUF1461)
NHGFBNON_00373 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NHGFBNON_00374 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHGFBNON_00375 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
NHGFBNON_00376 1.29e-83 - - - - - - - -
NHGFBNON_00377 3.41e-190 - - - - - - - -
NHGFBNON_00378 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00379 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
NHGFBNON_00380 4.76e-56 - - - - - - - -
NHGFBNON_00381 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NHGFBNON_00382 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00383 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NHGFBNON_00384 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_00385 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
NHGFBNON_00386 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NHGFBNON_00387 1.16e-242 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
NHGFBNON_00388 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
NHGFBNON_00389 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NHGFBNON_00390 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHGFBNON_00391 6.77e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHGFBNON_00392 3.95e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NHGFBNON_00393 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHGFBNON_00394 2.82e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHGFBNON_00395 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHGFBNON_00396 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHGFBNON_00397 9.93e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NHGFBNON_00398 1.79e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHGFBNON_00399 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NHGFBNON_00400 2.71e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NHGFBNON_00401 9.07e-158 - - - E - - - Methionine synthase
NHGFBNON_00402 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NHGFBNON_00403 2.62e-121 - - - - - - - -
NHGFBNON_00404 1.03e-198 - - - T - - - EAL domain
NHGFBNON_00405 4.71e-208 - - - GM - - - NmrA-like family
NHGFBNON_00406 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
NHGFBNON_00407 4.41e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NHGFBNON_00408 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
NHGFBNON_00409 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHGFBNON_00410 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NHGFBNON_00411 3.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHGFBNON_00412 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NHGFBNON_00413 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NHGFBNON_00414 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHGFBNON_00415 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHGFBNON_00416 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHGFBNON_00417 3.84e-218 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NHGFBNON_00418 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHGFBNON_00419 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NHGFBNON_00420 1.57e-123 - - - K - - - Acetyltransferase (GNAT) family
NHGFBNON_00421 1.29e-148 - - - GM - - - NAD(P)H-binding
NHGFBNON_00422 8.13e-208 mleR - - K - - - LysR family
NHGFBNON_00423 6.68e-139 - - - S ko:K07090 - ko00000 membrane transporter protein
NHGFBNON_00424 3.59e-26 - - - - - - - -
NHGFBNON_00425 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHGFBNON_00426 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHGFBNON_00427 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
NHGFBNON_00428 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHGFBNON_00429 4.71e-74 - - - S - - - SdpI/YhfL protein family
NHGFBNON_00430 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
NHGFBNON_00431 2.84e-82 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_00432 1.17e-270 yttB - - EGP - - - Major Facilitator
NHGFBNON_00433 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NHGFBNON_00434 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NHGFBNON_00435 0.0 yhdP - - S - - - Transporter associated domain
NHGFBNON_00436 2.97e-76 - - - - - - - -
NHGFBNON_00437 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHGFBNON_00438 2.2e-79 - - - - - - - -
NHGFBNON_00439 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
NHGFBNON_00440 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
NHGFBNON_00441 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHGFBNON_00442 6.08e-179 - - - - - - - -
NHGFBNON_00443 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHGFBNON_00444 3.53e-169 - - - K - - - Transcriptional regulator
NHGFBNON_00445 1.52e-204 - - - S - - - Putative esterase
NHGFBNON_00446 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NHGFBNON_00447 6.19e-284 - - - M - - - Glycosyl transferases group 1
NHGFBNON_00448 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
NHGFBNON_00449 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHGFBNON_00450 1.84e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NHGFBNON_00451 2.51e-103 uspA3 - - T - - - universal stress protein
NHGFBNON_00452 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NHGFBNON_00453 4.28e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NHGFBNON_00454 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NHGFBNON_00455 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
NHGFBNON_00456 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NHGFBNON_00457 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
NHGFBNON_00458 3.5e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NHGFBNON_00459 4.15e-78 - - - - - - - -
NHGFBNON_00460 4.05e-98 - - - - - - - -
NHGFBNON_00461 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
NHGFBNON_00462 1.57e-71 - - - - - - - -
NHGFBNON_00463 1.88e-55 - - - - - - - -
NHGFBNON_00464 2.72e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NHGFBNON_00465 9.89e-74 ytpP - - CO - - - Thioredoxin
NHGFBNON_00466 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
NHGFBNON_00467 1e-89 - - - - - - - -
NHGFBNON_00468 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NHGFBNON_00469 1.44e-65 - - - - - - - -
NHGFBNON_00470 1.23e-75 - - - - - - - -
NHGFBNON_00471 1.86e-210 - - - - - - - -
NHGFBNON_00472 1.4e-95 - - - K - - - Transcriptional regulator
NHGFBNON_00473 0.0 pepF2 - - E - - - Oligopeptidase F
NHGFBNON_00474 2.29e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
NHGFBNON_00475 6.21e-124 - - - V - - - VanZ like family
NHGFBNON_00476 1.87e-249 - - - V - - - Beta-lactamase
NHGFBNON_00477 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NHGFBNON_00478 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHGFBNON_00479 8.93e-71 - - - S - - - Pfam:DUF59
NHGFBNON_00480 1.05e-223 ydhF - - S - - - Aldo keto reductase
NHGFBNON_00481 2.42e-127 - - - FG - - - HIT domain
NHGFBNON_00482 4.9e-49 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NHGFBNON_00483 4.29e-101 - - - - - - - -
NHGFBNON_00484 3.73e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NHGFBNON_00485 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
NHGFBNON_00486 0.0 cadA - - P - - - P-type ATPase
NHGFBNON_00488 1.08e-82 - - - S - - - YjbR
NHGFBNON_00489 9.53e-285 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NHGFBNON_00490 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHGFBNON_00491 5.84e-255 glmS2 - - M - - - SIS domain
NHGFBNON_00492 3.58e-36 - - - S - - - Belongs to the LOG family
NHGFBNON_00493 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NHGFBNON_00494 9.04e-317 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NHGFBNON_00495 5e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_00496 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
NHGFBNON_00497 1.85e-207 - - - GM - - - NmrA-like family
NHGFBNON_00498 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
NHGFBNON_00499 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
NHGFBNON_00500 1.41e-86 yeaO - - S - - - Protein of unknown function, DUF488
NHGFBNON_00501 1.7e-70 - - - - - - - -
NHGFBNON_00502 2.03e-274 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NHGFBNON_00503 2.11e-82 - - - - - - - -
NHGFBNON_00504 1.36e-112 - - - - - - - -
NHGFBNON_00505 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHGFBNON_00506 2.27e-74 - - - - - - - -
NHGFBNON_00507 4.79e-21 - - - - - - - -
NHGFBNON_00508 3.57e-150 - - - GM - - - NmrA-like family
NHGFBNON_00509 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
NHGFBNON_00510 3.29e-203 - - - EG - - - EamA-like transporter family
NHGFBNON_00511 2.66e-155 - - - S - - - membrane
NHGFBNON_00512 1.47e-144 - - - S - - - VIT family
NHGFBNON_00513 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NHGFBNON_00514 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NHGFBNON_00515 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NHGFBNON_00516 4.26e-54 - - - - - - - -
NHGFBNON_00517 2.07e-97 - - - S - - - COG NOG18757 non supervised orthologous group
NHGFBNON_00518 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NHGFBNON_00519 7.21e-35 - - - - - - - -
NHGFBNON_00520 4.39e-66 - - - - - - - -
NHGFBNON_00521 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
NHGFBNON_00522 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NHGFBNON_00523 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NHGFBNON_00524 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
NHGFBNON_00525 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
NHGFBNON_00526 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NHGFBNON_00527 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NHGFBNON_00528 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NHGFBNON_00529 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NHGFBNON_00530 1.36e-209 yvgN - - C - - - Aldo keto reductase
NHGFBNON_00531 2.57e-171 - - - S - - - Putative threonine/serine exporter
NHGFBNON_00532 2.93e-102 - - - S - - - Threonine/Serine exporter, ThrE
NHGFBNON_00533 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
NHGFBNON_00534 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHGFBNON_00535 5.94e-118 ymdB - - S - - - Macro domain protein
NHGFBNON_00536 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
NHGFBNON_00537 1.58e-66 - - - - - - - -
NHGFBNON_00538 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
NHGFBNON_00539 0.0 - - - - - - - -
NHGFBNON_00540 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
NHGFBNON_00541 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00542 3.28e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NHGFBNON_00543 5.33e-114 - - - K - - - Winged helix DNA-binding domain
NHGFBNON_00544 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00545 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NHGFBNON_00546 4.45e-38 - - - - - - - -
NHGFBNON_00547 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
NHGFBNON_00548 2.04e-107 - - - M - - - PFAM NLP P60 protein
NHGFBNON_00549 6.18e-71 - - - - - - - -
NHGFBNON_00550 9.96e-82 - - - - - - - -
NHGFBNON_00552 8.86e-139 - - - - - - - -
NHGFBNON_00553 1.22e-68 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
NHGFBNON_00554 1.13e-204 - - - S ko:K07045 - ko00000 Amidohydrolase
NHGFBNON_00555 6.25e-132 - - - K - - - transcriptional regulator
NHGFBNON_00556 1.24e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NHGFBNON_00557 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHGFBNON_00558 3.55e-164 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
NHGFBNON_00559 2.93e-234 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NHGFBNON_00560 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NHGFBNON_00561 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHGFBNON_00562 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
NHGFBNON_00563 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
NHGFBNON_00564 1.34e-26 - - - - - - - -
NHGFBNON_00565 1.43e-124 dpsB - - P - - - Belongs to the Dps family
NHGFBNON_00566 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
NHGFBNON_00567 2.59e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NHGFBNON_00568 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NHGFBNON_00569 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHGFBNON_00570 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NHGFBNON_00571 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NHGFBNON_00572 1.83e-235 - - - S - - - Cell surface protein
NHGFBNON_00573 7.12e-159 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00574 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00575 1.58e-59 - - - - - - - -
NHGFBNON_00576 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
NHGFBNON_00577 1.03e-65 - - - - - - - -
NHGFBNON_00578 4.16e-314 - - - S - - - Putative metallopeptidase domain
NHGFBNON_00579 4.03e-283 - - - S - - - associated with various cellular activities
NHGFBNON_00580 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHGFBNON_00581 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
NHGFBNON_00582 1.24e-313 - - - P - - - Sodium:sulfate symporter transmembrane region
NHGFBNON_00583 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NHGFBNON_00584 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NHGFBNON_00585 1.37e-182 - - - S - - - zinc-ribbon domain
NHGFBNON_00587 4.29e-50 - - - - - - - -
NHGFBNON_00588 3.49e-170 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
NHGFBNON_00589 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NHGFBNON_00590 0.0 - - - I - - - acetylesterase activity
NHGFBNON_00591 2.25e-297 - - - M - - - Collagen binding domain
NHGFBNON_00592 1.4e-205 yicL - - EG - - - EamA-like transporter family
NHGFBNON_00593 1.24e-165 - - - E - - - lipolytic protein G-D-S-L family
NHGFBNON_00594 3.53e-227 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
NHGFBNON_00595 2.51e-145 - - - K - - - Transcriptional regulator C-terminal region
NHGFBNON_00596 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
NHGFBNON_00597 7.52e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NHGFBNON_00598 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NHGFBNON_00599 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
NHGFBNON_00600 8.08e-154 ydgI3 - - C - - - Nitroreductase family
NHGFBNON_00601 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NHGFBNON_00602 7.52e-139 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NHGFBNON_00603 6.48e-195 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NHGFBNON_00604 8.49e-217 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_00605 0.0 - - - - - - - -
NHGFBNON_00606 1.4e-82 - - - - - - - -
NHGFBNON_00607 7.52e-240 - - - S - - - Cell surface protein
NHGFBNON_00608 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00609 4.28e-71 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NHGFBNON_00610 1.67e-49 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NHGFBNON_00611 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_00612 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NHGFBNON_00613 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NHGFBNON_00614 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NHGFBNON_00615 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NHGFBNON_00617 1.15e-43 - - - - - - - -
NHGFBNON_00618 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
NHGFBNON_00619 2.88e-106 gtcA3 - - S - - - GtrA-like protein
NHGFBNON_00620 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
NHGFBNON_00621 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NHGFBNON_00622 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
NHGFBNON_00623 7.03e-62 - - - - - - - -
NHGFBNON_00624 1.81e-150 - - - S - - - SNARE associated Golgi protein
NHGFBNON_00625 1e-63 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NHGFBNON_00626 7.89e-124 - - - P - - - Cadmium resistance transporter
NHGFBNON_00627 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00628 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
NHGFBNON_00629 2.03e-84 - - - - - - - -
NHGFBNON_00630 7.85e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NHGFBNON_00631 1.21e-73 - - - - - - - -
NHGFBNON_00632 4.15e-193 - - - K - - - Helix-turn-helix domain
NHGFBNON_00633 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NHGFBNON_00634 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_00635 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_00636 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_00637 9.1e-237 - - - GM - - - Male sterility protein
NHGFBNON_00638 1.79e-100 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_00639 4.93e-38 - - - M - - - Lysin motif
NHGFBNON_00640 8.82e-44 - - - M - - - Lysin motif
NHGFBNON_00641 1.99e-138 - - - S - - - SdpI/YhfL protein family
NHGFBNON_00642 1.58e-72 nudA - - S - - - ASCH
NHGFBNON_00643 1.65e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NHGFBNON_00644 8.76e-121 - - - - - - - -
NHGFBNON_00645 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
NHGFBNON_00646 1.02e-280 - - - T - - - diguanylate cyclase
NHGFBNON_00647 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
NHGFBNON_00648 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
NHGFBNON_00649 5.78e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NHGFBNON_00650 3.05e-95 - - - - - - - -
NHGFBNON_00651 2.66e-167 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGFBNON_00652 2.67e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
NHGFBNON_00653 2.51e-150 - - - GM - - - NAD(P)H-binding
NHGFBNON_00654 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NHGFBNON_00655 6.7e-102 yphH - - S - - - Cupin domain
NHGFBNON_00656 3.55e-79 - - - I - - - sulfurtransferase activity
NHGFBNON_00657 1.56e-177 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
NHGFBNON_00658 3.41e-151 - - - GM - - - NAD(P)H-binding
NHGFBNON_00659 4.66e-277 - - - - - - - -
NHGFBNON_00660 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_00661 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00662 1.51e-225 - - - O - - - protein import
NHGFBNON_00663 2.77e-291 amd - - E - - - Peptidase family M20/M25/M40
NHGFBNON_00664 2.43e-208 yhxD - - IQ - - - KR domain
NHGFBNON_00666 9.38e-91 - - - - - - - -
NHGFBNON_00667 3.51e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
NHGFBNON_00668 0.0 - - - E - - - Amino Acid
NHGFBNON_00669 1.67e-86 lysM - - M - - - LysM domain
NHGFBNON_00670 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
NHGFBNON_00671 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NHGFBNON_00672 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NHGFBNON_00673 1.23e-57 - - - S - - - Cupredoxin-like domain
NHGFBNON_00674 1.36e-84 - - - S - - - Cupredoxin-like domain
NHGFBNON_00675 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NHGFBNON_00676 2.81e-181 - - - K - - - Helix-turn-helix domain
NHGFBNON_00677 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
NHGFBNON_00678 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHGFBNON_00679 0.0 - - - - - - - -
NHGFBNON_00680 2.69e-99 - - - - - - - -
NHGFBNON_00681 1.06e-238 - - - S - - - Cell surface protein
NHGFBNON_00682 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00683 2.67e-225 - - - C - - - Alcohol dehydrogenase GroES-like domain
NHGFBNON_00684 5.83e-87 - - - S - - - Iron-sulphur cluster biosynthesis
NHGFBNON_00685 8.45e-147 - - - S - - - GyrI-like small molecule binding domain
NHGFBNON_00686 4.55e-243 ynjC - - S - - - Cell surface protein
NHGFBNON_00687 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00688 1.47e-83 - - - - - - - -
NHGFBNON_00689 1.28e-297 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NHGFBNON_00690 4.8e-156 - - - - - - - -
NHGFBNON_00691 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
NHGFBNON_00692 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
NHGFBNON_00693 1.81e-272 - - - EGP - - - Major Facilitator
NHGFBNON_00694 4.52e-147 - - - M - - - ErfK YbiS YcfS YnhG
NHGFBNON_00695 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NHGFBNON_00696 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHGFBNON_00697 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHGFBNON_00698 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00699 2.65e-216 - - - GM - - - NmrA-like family
NHGFBNON_00700 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NHGFBNON_00701 0.0 - - - M - - - Glycosyl hydrolases family 25
NHGFBNON_00702 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
NHGFBNON_00703 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
NHGFBNON_00704 3.27e-170 - - - S - - - KR domain
NHGFBNON_00705 2.46e-127 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00706 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
NHGFBNON_00707 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
NHGFBNON_00708 1.97e-229 ydhF - - S - - - Aldo keto reductase
NHGFBNON_00711 0.0 yfjF - - U - - - Sugar (and other) transporter
NHGFBNON_00712 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00713 1.42e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NHGFBNON_00714 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHGFBNON_00715 1.49e-227 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHGFBNON_00716 3.32e-219 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHGFBNON_00717 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00718 3.89e-210 - - - GM - - - NmrA-like family
NHGFBNON_00719 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGFBNON_00720 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NHGFBNON_00721 3.69e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NHGFBNON_00722 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_00723 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHGFBNON_00724 4.28e-233 - - - S - - - Bacterial protein of unknown function (DUF916)
NHGFBNON_00725 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_00726 2.83e-267 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NHGFBNON_00727 1.97e-151 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_00728 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHGFBNON_00729 7.2e-61 - - - S - - - Enterocin A Immunity
NHGFBNON_00730 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NHGFBNON_00731 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_00732 2.66e-172 - - - - - - - -
NHGFBNON_00733 9.38e-139 pncA - - Q - - - Isochorismatase family
NHGFBNON_00734 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHGFBNON_00735 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
NHGFBNON_00736 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NHGFBNON_00737 6.09e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NHGFBNON_00738 1.77e-201 - - - K - - - Helix-turn-helix domain, rpiR family
NHGFBNON_00739 2.89e-224 ccpB - - K - - - lacI family
NHGFBNON_00740 4.13e-180 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NHGFBNON_00741 1.81e-160 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
NHGFBNON_00742 5.85e-226 - - - K - - - sugar-binding domain protein
NHGFBNON_00743 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NHGFBNON_00744 1.38e-171 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NHGFBNON_00745 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHGFBNON_00746 3.16e-232 - - - GK - - - ROK family
NHGFBNON_00747 8.1e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NHGFBNON_00748 2.43e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHGFBNON_00749 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NHGFBNON_00750 2.57e-128 - - - C - - - Nitroreductase family
NHGFBNON_00751 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
NHGFBNON_00752 1.85e-248 - - - S - - - domain, Protein
NHGFBNON_00753 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_00754 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NHGFBNON_00755 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NHGFBNON_00756 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHGFBNON_00757 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
NHGFBNON_00758 0.0 - - - M - - - domain protein
NHGFBNON_00759 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NHGFBNON_00760 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
NHGFBNON_00761 1.45e-46 - - - - - - - -
NHGFBNON_00762 4.7e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHGFBNON_00763 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHGFBNON_00764 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
NHGFBNON_00765 1.71e-67 - - - S - - - Domain of unknown function (DU1801)
NHGFBNON_00766 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NHGFBNON_00767 1.07e-282 ysaA - - V - - - RDD family
NHGFBNON_00768 6.46e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
NHGFBNON_00769 1.09e-273 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHGFBNON_00770 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHGFBNON_00771 4.51e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHGFBNON_00772 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NHGFBNON_00773 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHGFBNON_00774 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHGFBNON_00775 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHGFBNON_00776 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHGFBNON_00777 5.11e-67 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NHGFBNON_00778 3.38e-252 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHGFBNON_00779 6.8e-123 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NHGFBNON_00780 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
NHGFBNON_00781 9.51e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NHGFBNON_00782 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NHGFBNON_00783 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_00784 1.73e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NHGFBNON_00785 2.79e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_00786 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NHGFBNON_00787 3.52e-311 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NHGFBNON_00788 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NHGFBNON_00789 5.97e-210 - - - S - - - Uncharacterised protein, DegV family COG1307
NHGFBNON_00790 5.32e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHGFBNON_00791 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NHGFBNON_00792 9.2e-62 - - - - - - - -
NHGFBNON_00793 4.74e-106 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHGFBNON_00794 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHGFBNON_00795 4.91e-265 yacL - - S - - - domain protein
NHGFBNON_00796 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHGFBNON_00797 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NHGFBNON_00798 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHGFBNON_00799 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHGFBNON_00800 1.75e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NHGFBNON_00801 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
NHGFBNON_00802 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NHGFBNON_00803 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHGFBNON_00804 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NHGFBNON_00805 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_00806 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHGFBNON_00807 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHGFBNON_00808 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHGFBNON_00809 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHGFBNON_00810 2.04e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NHGFBNON_00811 1.78e-88 - - - L - - - nuclease
NHGFBNON_00812 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHGFBNON_00813 3.52e-47 - - - K - - - Helix-turn-helix domain
NHGFBNON_00814 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NHGFBNON_00815 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHGFBNON_00816 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHGFBNON_00817 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NHGFBNON_00818 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NHGFBNON_00819 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHGFBNON_00820 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHGFBNON_00821 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHGFBNON_00822 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHGFBNON_00823 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
NHGFBNON_00824 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHGFBNON_00825 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
NHGFBNON_00826 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NHGFBNON_00827 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
NHGFBNON_00828 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHGFBNON_00829 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NHGFBNON_00830 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NHGFBNON_00831 2.18e-269 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NHGFBNON_00832 1.62e-186 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
NHGFBNON_00833 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_00834 5.35e-177 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
NHGFBNON_00835 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NHGFBNON_00836 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NHGFBNON_00837 4.43e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NHGFBNON_00838 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NHGFBNON_00839 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHGFBNON_00840 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHGFBNON_00841 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
NHGFBNON_00842 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NHGFBNON_00843 7.89e-245 mocA - - S - - - Oxidoreductase
NHGFBNON_00844 9.46e-315 yfmL - - L - - - DEAD DEAH box helicase
NHGFBNON_00846 3.93e-99 - - - T - - - Universal stress protein family
NHGFBNON_00847 5.45e-314 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_00848 9.96e-198 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_00850 7.62e-97 - - - - - - - -
NHGFBNON_00851 2.9e-139 - - - - - - - -
NHGFBNON_00852 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NHGFBNON_00853 1.63e-281 pbpX - - V - - - Beta-lactamase
NHGFBNON_00854 1.12e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHGFBNON_00855 7.42e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NHGFBNON_00856 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHGFBNON_00857 7.7e-43 - - - E - - - Zn peptidase
NHGFBNON_00858 1.6e-35 - - - K - - - Helix-turn-helix XRE-family like proteins
NHGFBNON_00860 1.81e-69 pbpX2 - - V - - - Beta-lactamase
NHGFBNON_00861 6.7e-25 - - - S - - - Glycosyl transferase, family 2
NHGFBNON_00862 1.09e-61 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHGFBNON_00863 3.13e-53 - - - S - - - Bacterial transferase hexapeptide (six repeats)
NHGFBNON_00864 3.21e-168 - - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
NHGFBNON_00865 6.32e-68 - - - G - - - Glycosyltransferase Family 4
NHGFBNON_00866 1.46e-68 - - - - - - - -
NHGFBNON_00868 1.72e-49 - - - G - - - PFAM glycoside hydrolase family 39
NHGFBNON_00869 1.53e-187 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHGFBNON_00870 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NHGFBNON_00871 1.39e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHGFBNON_00872 4.88e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHGFBNON_00873 1.05e-188 cps2I - - S - - - Psort location CytoplasmicMembrane, score
NHGFBNON_00874 2.44e-129 - - - L - - - Integrase
NHGFBNON_00875 1.12e-168 epsB - - M - - - biosynthesis protein
NHGFBNON_00876 4.99e-165 ywqD - - D - - - Capsular exopolysaccharide family
NHGFBNON_00877 1.49e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NHGFBNON_00878 3.81e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NHGFBNON_00879 1.19e-159 tuaA - - M - - - Bacterial sugar transferase
NHGFBNON_00880 1.35e-73 - - - M - - - Glycosyl transferase family 2
NHGFBNON_00882 1.7e-128 galnac-T15 - - M ko:K07011 - ko00000 Glycosyltransferase like family 2
NHGFBNON_00883 1.33e-162 - - - S ko:K16710 - ko00000 slime layer polysaccharide biosynthetic process
NHGFBNON_00884 1.24e-182 cps2J - - S - - - Polysaccharide biosynthesis protein
NHGFBNON_00885 2.91e-80 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NHGFBNON_00886 7.65e-24 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
NHGFBNON_00888 1.4e-12 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
NHGFBNON_00889 8.61e-27 - - - L - - - Helix-turn-helix domain
NHGFBNON_00890 2.6e-16 - - - L - - - Helix-turn-helix domain
NHGFBNON_00891 1.17e-66 - - - L ko:K07497 - ko00000 hmm pf00665
NHGFBNON_00893 1.84e-85 - - - S - - - AAA ATPase domain
NHGFBNON_00895 6.78e-17 - - - S - - - SIR2-like domain
NHGFBNON_00896 7.01e-170 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NHGFBNON_00897 6.61e-229 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NHGFBNON_00898 6.91e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NHGFBNON_00899 2.76e-260 cps3D - - - - - - -
NHGFBNON_00900 2.92e-145 cps3E - - - - - - -
NHGFBNON_00901 1.75e-209 cps3F - - - - - - -
NHGFBNON_00902 2.71e-260 cps3H - - - - - - -
NHGFBNON_00903 5.67e-257 cps3I - - G - - - Acyltransferase family
NHGFBNON_00904 2.94e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
NHGFBNON_00905 6.97e-304 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NHGFBNON_00906 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NHGFBNON_00907 9.02e-70 - - - - - - - -
NHGFBNON_00908 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
NHGFBNON_00909 8.39e-38 - - - - - - - -
NHGFBNON_00910 4.14e-132 - - - K - - - DNA-templated transcription, initiation
NHGFBNON_00911 1.15e-169 - - - - - - - -
NHGFBNON_00912 4.1e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NHGFBNON_00913 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NHGFBNON_00914 1.6e-169 lytE - - M - - - NlpC/P60 family
NHGFBNON_00915 3.97e-64 - - - K - - - sequence-specific DNA binding
NHGFBNON_00916 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
NHGFBNON_00917 1.67e-166 pbpX - - V - - - Beta-lactamase
NHGFBNON_00918 8.52e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NHGFBNON_00919 1.13e-257 yueF - - S - - - AI-2E family transporter
NHGFBNON_00920 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
NHGFBNON_00921 8.78e-287 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NHGFBNON_00922 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NHGFBNON_00923 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NHGFBNON_00924 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NHGFBNON_00925 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHGFBNON_00926 0.0 - - - - - - - -
NHGFBNON_00927 2.12e-252 - - - M - - - MucBP domain
NHGFBNON_00928 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
NHGFBNON_00929 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
NHGFBNON_00930 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
NHGFBNON_00931 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NHGFBNON_00932 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHGFBNON_00933 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHGFBNON_00934 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHGFBNON_00935 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHGFBNON_00936 4.54e-54 - - - - - - - -
NHGFBNON_00938 4.41e-316 - - - EGP - - - Major Facilitator
NHGFBNON_00939 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NHGFBNON_00940 1.73e-108 cvpA - - S - - - Colicin V production protein
NHGFBNON_00941 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHGFBNON_00942 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NHGFBNON_00943 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
NHGFBNON_00944 9.16e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHGFBNON_00945 6.2e-131 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NHGFBNON_00946 3.94e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
NHGFBNON_00947 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NHGFBNON_00948 8.03e-28 - - - - - - - -
NHGFBNON_00949 7.52e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NHGFBNON_00950 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NHGFBNON_00951 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NHGFBNON_00952 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NHGFBNON_00953 3.3e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NHGFBNON_00954 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NHGFBNON_00955 1.54e-228 ydbI - - K - - - AI-2E family transporter
NHGFBNON_00956 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHGFBNON_00957 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NHGFBNON_00959 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
NHGFBNON_00960 1.88e-106 - - - - - - - -
NHGFBNON_00962 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHGFBNON_00963 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NHGFBNON_00964 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHGFBNON_00965 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHGFBNON_00966 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHGFBNON_00967 2.49e-73 - - - S - - - Enterocin A Immunity
NHGFBNON_00968 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NHGFBNON_00969 1.22e-252 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NHGFBNON_00970 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
NHGFBNON_00971 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
NHGFBNON_00972 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
NHGFBNON_00973 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
NHGFBNON_00974 1.03e-34 - - - - - - - -
NHGFBNON_00975 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
NHGFBNON_00976 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
NHGFBNON_00977 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
NHGFBNON_00978 9.38e-134 - - - J - - - Acetyltransferase (GNAT) domain
NHGFBNON_00979 7.93e-217 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NHGFBNON_00980 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
NHGFBNON_00981 1.28e-77 - - - S - - - Enterocin A Immunity
NHGFBNON_00982 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NHGFBNON_00983 3.32e-135 - - - - - - - -
NHGFBNON_00984 8.44e-304 - - - S - - - module of peptide synthetase
NHGFBNON_00985 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
NHGFBNON_00987 1.46e-163 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
NHGFBNON_00988 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_00989 8.79e-199 - - - GM - - - NmrA-like family
NHGFBNON_00990 4.08e-101 - - - K - - - MerR family regulatory protein
NHGFBNON_00991 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHGFBNON_00992 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
NHGFBNON_00993 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_00994 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
NHGFBNON_00995 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
NHGFBNON_00996 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NHGFBNON_00997 8.69e-191 - - - S - - - haloacid dehalogenase-like hydrolase
NHGFBNON_00998 5.67e-196 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NHGFBNON_00999 3.91e-211 - - - K - - - LysR substrate binding domain
NHGFBNON_01000 6.36e-297 - - - - - - - -
NHGFBNON_01001 2.01e-307 - - - S - - - Neutral/alkaline non-lysosomal ceramidase, N-terminal
NHGFBNON_01002 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_01003 4.17e-263 - 4.1.1.45 - E ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
NHGFBNON_01004 6.26e-101 - - - - - - - -
NHGFBNON_01005 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHGFBNON_01006 3.56e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_01007 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NHGFBNON_01008 7.52e-263 - - - S - - - DUF218 domain
NHGFBNON_01009 1.57e-234 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NHGFBNON_01010 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NHGFBNON_01011 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_01012 4.17e-167 - - - S - - - Putative adhesin
NHGFBNON_01013 2.1e-133 - - - S - - - Protein of unknown function (DUF1700)
NHGFBNON_01014 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_01015 1.07e-127 - - - KT - - - response to antibiotic
NHGFBNON_01016 7.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NHGFBNON_01017 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_01018 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_01019 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NHGFBNON_01020 2.07e-302 - - - EK - - - Aminotransferase, class I
NHGFBNON_01021 3.36e-216 - - - K - - - LysR substrate binding domain
NHGFBNON_01022 2.12e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_01023 3.45e-198 - - - S - - - Bacterial membrane protein, YfhO
NHGFBNON_01024 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NHGFBNON_01025 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NHGFBNON_01026 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NHGFBNON_01027 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NHGFBNON_01028 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NHGFBNON_01029 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NHGFBNON_01030 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHGFBNON_01031 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
NHGFBNON_01032 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHGFBNON_01033 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHGFBNON_01034 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
NHGFBNON_01035 1.14e-159 vanR - - K - - - response regulator
NHGFBNON_01036 5.61e-273 hpk31 - - T - - - Histidine kinase
NHGFBNON_01037 2.18e-304 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHGFBNON_01038 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NHGFBNON_01039 2.05e-167 - - - E - - - branched-chain amino acid
NHGFBNON_01040 5.93e-73 - - - S - - - branched-chain amino acid
NHGFBNON_01041 9.65e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
NHGFBNON_01042 1.49e-72 - - - - - - - -
NHGFBNON_01043 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
NHGFBNON_01044 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
NHGFBNON_01045 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
NHGFBNON_01046 1.66e-259 pkn2 - - KLT - - - Protein tyrosine kinase
NHGFBNON_01047 9.51e-210 - - - - - - - -
NHGFBNON_01048 1.05e-294 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NHGFBNON_01049 5.21e-151 - - - - - - - -
NHGFBNON_01050 9.28e-271 xylR - - GK - - - ROK family
NHGFBNON_01051 9.26e-233 ydbI - - K - - - AI-2E family transporter
NHGFBNON_01052 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHGFBNON_01053 6.79e-53 - - - - - - - -
NHGFBNON_01055 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
NHGFBNON_01056 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
NHGFBNON_01057 6.49e-135 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_01058 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
NHGFBNON_01059 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
NHGFBNON_01060 5.35e-102 - - - GM - - - SnoaL-like domain
NHGFBNON_01061 1.93e-139 - - - GM - - - NAD(P)H-binding
NHGFBNON_01062 4.01e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NHGFBNON_01063 1.75e-149 yciB - - M - - - ErfK YbiS YcfS YnhG
NHGFBNON_01064 3e-47 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHGFBNON_01065 5.19e-50 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
NHGFBNON_01066 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NHGFBNON_01067 5.31e-66 - - - K - - - Helix-turn-helix domain
NHGFBNON_01068 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_01069 2.7e-76 - - - - - - - -
NHGFBNON_01070 5.52e-55 - - - K - - - HxlR-like helix-turn-helix
NHGFBNON_01071 1.26e-137 yoaZ - - S - - - intracellular protease amidase
NHGFBNON_01072 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
NHGFBNON_01073 1.57e-279 - - - S - - - Membrane
NHGFBNON_01074 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
NHGFBNON_01075 3.41e-31 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_01076 2.65e-52 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NHGFBNON_01077 5.15e-16 - - - - - - - -
NHGFBNON_01078 0.0 - - - L ko:K07487 - ko00000 Transposase
NHGFBNON_01079 2.09e-85 - - - - - - - -
NHGFBNON_01080 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_01081 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_01082 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
NHGFBNON_01083 1.29e-254 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NHGFBNON_01084 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NHGFBNON_01085 2.05e-153 - - - I - - - phosphatase
NHGFBNON_01086 3.88e-198 - - - I - - - alpha/beta hydrolase fold
NHGFBNON_01087 1.23e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NHGFBNON_01088 1.7e-118 - - - K - - - Transcriptional regulator
NHGFBNON_01089 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NHGFBNON_01090 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NHGFBNON_01091 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NHGFBNON_01092 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
NHGFBNON_01093 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHGFBNON_01101 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NHGFBNON_01102 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NHGFBNON_01103 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_01104 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHGFBNON_01105 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHGFBNON_01106 8.58e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NHGFBNON_01107 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHGFBNON_01108 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHGFBNON_01109 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHGFBNON_01110 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NHGFBNON_01111 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHGFBNON_01112 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NHGFBNON_01113 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHGFBNON_01114 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHGFBNON_01115 1.07e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHGFBNON_01116 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHGFBNON_01117 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHGFBNON_01118 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHGFBNON_01119 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NHGFBNON_01120 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHGFBNON_01121 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHGFBNON_01122 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHGFBNON_01123 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHGFBNON_01124 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHGFBNON_01125 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHGFBNON_01126 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHGFBNON_01127 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHGFBNON_01128 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NHGFBNON_01129 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NHGFBNON_01130 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHGFBNON_01131 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHGFBNON_01132 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHGFBNON_01133 2.28e-77 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHGFBNON_01134 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHGFBNON_01135 1.8e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHGFBNON_01136 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NHGFBNON_01137 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHGFBNON_01138 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
NHGFBNON_01139 5.37e-112 - - - S - - - NusG domain II
NHGFBNON_01140 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NHGFBNON_01141 3.19e-194 - - - S - - - FMN_bind
NHGFBNON_01142 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHGFBNON_01143 3.42e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHGFBNON_01144 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHGFBNON_01145 5.86e-185 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHGFBNON_01146 7.21e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHGFBNON_01147 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHGFBNON_01148 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NHGFBNON_01149 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
NHGFBNON_01150 5.79e-234 - - - S - - - Membrane
NHGFBNON_01151 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NHGFBNON_01152 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHGFBNON_01153 7.53e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHGFBNON_01154 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
NHGFBNON_01155 1.82e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHGFBNON_01156 4.93e-275 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NHGFBNON_01157 3.05e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
NHGFBNON_01158 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
NHGFBNON_01159 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
NHGFBNON_01160 1.28e-253 - - - K - - - Helix-turn-helix domain
NHGFBNON_01161 1.57e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NHGFBNON_01162 1.18e-169 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHGFBNON_01163 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NHGFBNON_01164 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NHGFBNON_01165 1.18e-66 - - - - - - - -
NHGFBNON_01166 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHGFBNON_01167 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NHGFBNON_01168 7.14e-229 citR - - K - - - sugar-binding domain protein
NHGFBNON_01169 3.19e-263 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NHGFBNON_01170 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NHGFBNON_01171 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NHGFBNON_01172 3.32e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NHGFBNON_01173 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NHGFBNON_01175 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NHGFBNON_01176 6.56e-188 - - - - - - - -
NHGFBNON_01177 6.14e-133 - - - L - - - Phage integrase family
NHGFBNON_01178 1.04e-82 - - - - - - - -
NHGFBNON_01179 7.81e-37 - - - - - - - -
NHGFBNON_01181 7.51e-105 - - - - - - - -
NHGFBNON_01182 3.39e-138 - - - - - - - -
NHGFBNON_01183 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NHGFBNON_01184 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_01185 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NHGFBNON_01186 0.0 - - - - - - - -
NHGFBNON_01187 4.75e-80 - - - - - - - -
NHGFBNON_01188 3.36e-248 - - - S - - - Fn3-like domain
NHGFBNON_01189 1.9e-136 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_01190 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
NHGFBNON_01191 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHGFBNON_01192 6.76e-73 - - - - - - - -
NHGFBNON_01193 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NHGFBNON_01194 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_01195 9.53e-284 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_01196 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
NHGFBNON_01197 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHGFBNON_01198 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
NHGFBNON_01199 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHGFBNON_01200 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NHGFBNON_01201 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NHGFBNON_01202 3.04e-29 - - - S - - - Virus attachment protein p12 family
NHGFBNON_01203 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NHGFBNON_01204 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
NHGFBNON_01205 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NHGFBNON_01206 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NHGFBNON_01207 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHGFBNON_01208 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NHGFBNON_01209 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NHGFBNON_01210 6.87e-236 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NHGFBNON_01211 1.15e-161 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NHGFBNON_01212 6.56e-211 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHGFBNON_01213 6.7e-107 - - - C - - - Flavodoxin
NHGFBNON_01214 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
NHGFBNON_01215 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
NHGFBNON_01216 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHGFBNON_01217 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
NHGFBNON_01218 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
NHGFBNON_01219 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NHGFBNON_01220 4.87e-205 - - - H - - - geranyltranstransferase activity
NHGFBNON_01221 4.32e-233 - - - - - - - -
NHGFBNON_01222 6.1e-64 - - - - - - - -
NHGFBNON_01223 7.76e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
NHGFBNON_01224 8.17e-242 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
NHGFBNON_01225 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
NHGFBNON_01226 8.84e-52 - - - - - - - -
NHGFBNON_01227 5.73e-129 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHGFBNON_01228 3.11e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NHGFBNON_01229 9.62e-116 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NHGFBNON_01230 5.2e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
NHGFBNON_01231 9.07e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NHGFBNON_01232 1.27e-250 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NHGFBNON_01233 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHGFBNON_01234 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NHGFBNON_01235 8.2e-127 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
NHGFBNON_01236 2.69e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
NHGFBNON_01237 8.63e-226 - - - - - - - -
NHGFBNON_01238 1.8e-96 - - - - - - - -
NHGFBNON_01240 5.12e-46 - - - S - - - Phage Mu protein F like protein
NHGFBNON_01242 4.45e-58 - - - S - - - Phage minor structural protein GP20
NHGFBNON_01243 3.46e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NHGFBNON_01244 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHGFBNON_01245 1.85e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHGFBNON_01246 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHGFBNON_01247 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHGFBNON_01248 3.62e-123 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NHGFBNON_01249 1.91e-143 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NHGFBNON_01250 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHGFBNON_01251 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHGFBNON_01252 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NHGFBNON_01253 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHGFBNON_01254 2.76e-74 - - - - - - - -
NHGFBNON_01255 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NHGFBNON_01256 4.79e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NHGFBNON_01257 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
NHGFBNON_01258 6.86e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NHGFBNON_01259 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NHGFBNON_01260 6.32e-114 - - - - - - - -
NHGFBNON_01261 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NHGFBNON_01262 2.57e-274 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NHGFBNON_01263 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NHGFBNON_01264 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHGFBNON_01265 1.71e-149 yqeK - - H - - - Hydrolase, HD family
NHGFBNON_01266 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHGFBNON_01267 3.3e-180 yqeM - - Q - - - Methyltransferase
NHGFBNON_01268 1.02e-278 ylbM - - S - - - Belongs to the UPF0348 family
NHGFBNON_01269 2.12e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NHGFBNON_01270 7.2e-123 - - - S - - - Peptidase propeptide and YPEB domain
NHGFBNON_01271 1.13e-225 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHGFBNON_01272 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHGFBNON_01273 1.8e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NHGFBNON_01274 1.38e-155 csrR - - K - - - response regulator
NHGFBNON_01275 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHGFBNON_01276 1.59e-217 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NHGFBNON_01277 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NHGFBNON_01278 5.55e-288 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHGFBNON_01279 1.77e-122 - - - S - - - SdpI/YhfL protein family
NHGFBNON_01280 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHGFBNON_01281 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NHGFBNON_01282 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHGFBNON_01283 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHGFBNON_01284 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
NHGFBNON_01285 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHGFBNON_01286 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHGFBNON_01287 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHGFBNON_01288 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NHGFBNON_01289 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHGFBNON_01290 9.72e-146 - - - S - - - membrane
NHGFBNON_01291 5.72e-99 - - - K - - - LytTr DNA-binding domain
NHGFBNON_01292 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
NHGFBNON_01293 0.0 - - - S - - - membrane
NHGFBNON_01294 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NHGFBNON_01295 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NHGFBNON_01296 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHGFBNON_01297 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NHGFBNON_01298 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NHGFBNON_01299 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NHGFBNON_01300 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NHGFBNON_01301 6.68e-89 yqhL - - P - - - Rhodanese-like protein
NHGFBNON_01302 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NHGFBNON_01303 9.07e-178 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NHGFBNON_01304 1.33e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHGFBNON_01305 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NHGFBNON_01306 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NHGFBNON_01307 5.08e-205 - - - - - - - -
NHGFBNON_01308 1.34e-232 - - - - - - - -
NHGFBNON_01309 2.92e-126 - - - S - - - Protein conserved in bacteria
NHGFBNON_01310 3.11e-73 - - - - - - - -
NHGFBNON_01311 2.97e-41 - - - - - - - -
NHGFBNON_01314 9.81e-27 - - - - - - - -
NHGFBNON_01315 4.04e-125 - - - K - - - Transcriptional regulator
NHGFBNON_01316 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NHGFBNON_01317 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NHGFBNON_01318 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NHGFBNON_01319 2.46e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NHGFBNON_01320 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHGFBNON_01321 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NHGFBNON_01322 4.86e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHGFBNON_01323 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHGFBNON_01324 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHGFBNON_01325 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHGFBNON_01326 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHGFBNON_01327 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NHGFBNON_01328 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NHGFBNON_01329 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NHGFBNON_01330 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_01331 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_01332 6.31e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHGFBNON_01333 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_01334 3.51e-74 - - - - - - - -
NHGFBNON_01335 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NHGFBNON_01336 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHGFBNON_01337 1.24e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHGFBNON_01338 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHGFBNON_01339 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHGFBNON_01340 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHGFBNON_01341 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NHGFBNON_01342 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NHGFBNON_01343 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHGFBNON_01344 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NHGFBNON_01345 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NHGFBNON_01346 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NHGFBNON_01347 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
NHGFBNON_01348 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NHGFBNON_01349 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHGFBNON_01350 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHGFBNON_01351 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHGFBNON_01352 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHGFBNON_01353 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NHGFBNON_01354 1.1e-297 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHGFBNON_01355 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHGFBNON_01356 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHGFBNON_01357 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NHGFBNON_01358 4.07e-52 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NHGFBNON_01359 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHGFBNON_01360 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NHGFBNON_01361 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHGFBNON_01362 6.21e-68 - - - - - - - -
NHGFBNON_01363 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHGFBNON_01364 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NHGFBNON_01365 9.06e-112 - - - - - - - -
NHGFBNON_01366 1.18e-178 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NHGFBNON_01367 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
NHGFBNON_01368 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
NHGFBNON_01369 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
NHGFBNON_01370 7.03e-225 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHGFBNON_01371 1.66e-156 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NHGFBNON_01372 1.83e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NHGFBNON_01373 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHGFBNON_01374 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHGFBNON_01375 4.84e-125 entB - - Q - - - Isochorismatase family
NHGFBNON_01376 2.9e-226 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
NHGFBNON_01377 1.53e-177 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NHGFBNON_01378 1.09e-79 - - - S - - - Protein of unknown function (DUF1648)
NHGFBNON_01379 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGFBNON_01380 8.02e-230 yneE - - K - - - Transcriptional regulator
NHGFBNON_01381 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHGFBNON_01382 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHGFBNON_01383 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHGFBNON_01384 4.93e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NHGFBNON_01385 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NHGFBNON_01386 1.54e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHGFBNON_01387 2.5e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHGFBNON_01388 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NHGFBNON_01389 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NHGFBNON_01390 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHGFBNON_01391 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NHGFBNON_01392 7.68e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NHGFBNON_01393 1.75e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NHGFBNON_01394 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NHGFBNON_01395 3.73e-207 - - - K - - - LysR substrate binding domain
NHGFBNON_01396 4.94e-114 ykhA - - I - - - Thioesterase superfamily
NHGFBNON_01397 5.36e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHGFBNON_01398 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
NHGFBNON_01399 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NHGFBNON_01400 6.5e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NHGFBNON_01401 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NHGFBNON_01402 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHGFBNON_01403 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHGFBNON_01404 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NHGFBNON_01405 2.24e-148 yjbH - - Q - - - Thioredoxin
NHGFBNON_01406 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NHGFBNON_01407 3.19e-264 coiA - - S ko:K06198 - ko00000 Competence protein
NHGFBNON_01408 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHGFBNON_01409 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHGFBNON_01410 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
NHGFBNON_01411 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NHGFBNON_01433 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHGFBNON_01434 3.74e-206 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NHGFBNON_01436 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHGFBNON_01437 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NHGFBNON_01438 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHGFBNON_01439 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NHGFBNON_01440 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NHGFBNON_01441 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
NHGFBNON_01442 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NHGFBNON_01443 8.62e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHGFBNON_01444 7.01e-76 ftsL - - D - - - Cell division protein FtsL
NHGFBNON_01445 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NHGFBNON_01446 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHGFBNON_01447 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHGFBNON_01448 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHGFBNON_01449 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHGFBNON_01450 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHGFBNON_01451 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHGFBNON_01452 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHGFBNON_01453 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NHGFBNON_01454 3.41e-186 ylmH - - S - - - S4 domain protein
NHGFBNON_01455 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NHGFBNON_01456 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHGFBNON_01457 3.64e-101 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
NHGFBNON_01458 1.47e-100 - - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NHGFBNON_01459 2.57e-47 - - - K - - - LytTr DNA-binding domain
NHGFBNON_01460 2.05e-20 - - - S - - - Protein of unknown function (DUF3021)
NHGFBNON_01461 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHGFBNON_01462 1.43e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NHGFBNON_01463 7.74e-47 - - - - - - - -
NHGFBNON_01464 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHGFBNON_01465 1.06e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NHGFBNON_01466 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NHGFBNON_01467 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHGFBNON_01468 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NHGFBNON_01469 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
NHGFBNON_01470 3.57e-154 - - - N - - - WxL domain surface cell wall-binding
NHGFBNON_01471 7.05e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
NHGFBNON_01472 0.0 - - - N - - - domain, Protein
NHGFBNON_01473 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
NHGFBNON_01474 1.02e-155 - - - S - - - repeat protein
NHGFBNON_01475 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHGFBNON_01476 1.6e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHGFBNON_01477 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NHGFBNON_01478 6.21e-39 - - - - - - - -
NHGFBNON_01479 5.96e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NHGFBNON_01480 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHGFBNON_01481 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
NHGFBNON_01482 6.45e-111 - - - - - - - -
NHGFBNON_01483 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHGFBNON_01484 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NHGFBNON_01485 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NHGFBNON_01486 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHGFBNON_01487 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NHGFBNON_01488 2.51e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
NHGFBNON_01489 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
NHGFBNON_01490 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NHGFBNON_01491 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NHGFBNON_01492 1.1e-257 - - - - - - - -
NHGFBNON_01493 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHGFBNON_01494 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHGFBNON_01495 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
NHGFBNON_01496 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NHGFBNON_01497 9.9e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHGFBNON_01498 2.21e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NHGFBNON_01499 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHGFBNON_01500 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NHGFBNON_01501 3.84e-316 ymfH - - S - - - Peptidase M16
NHGFBNON_01502 1.44e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
NHGFBNON_01503 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NHGFBNON_01504 4.34e-198 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NHGFBNON_01505 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_01506 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NHGFBNON_01507 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NHGFBNON_01508 2.2e-149 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NHGFBNON_01509 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NHGFBNON_01510 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NHGFBNON_01511 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NHGFBNON_01512 1.35e-149 radC - - L ko:K03630 - ko00000 DNA repair protein
NHGFBNON_01513 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHGFBNON_01514 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHGFBNON_01515 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHGFBNON_01516 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
NHGFBNON_01517 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
NHGFBNON_01518 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHGFBNON_01519 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NHGFBNON_01520 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NHGFBNON_01521 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_01522 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NHGFBNON_01523 5.02e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NHGFBNON_01524 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NHGFBNON_01525 5.91e-297 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
NHGFBNON_01526 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
NHGFBNON_01527 3.9e-143 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NHGFBNON_01528 1.97e-99 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NHGFBNON_01529 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_01530 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NHGFBNON_01531 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NHGFBNON_01532 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHGFBNON_01533 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NHGFBNON_01534 1.64e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NHGFBNON_01535 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NHGFBNON_01536 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NHGFBNON_01537 3.51e-252 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NHGFBNON_01538 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_01539 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NHGFBNON_01540 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
NHGFBNON_01542 1.07e-208 - - - K - - - Transcriptional regulator
NHGFBNON_01543 2.95e-207 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NHGFBNON_01544 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
NHGFBNON_01545 2.45e-101 - - - K - - - Winged helix DNA-binding domain
NHGFBNON_01546 0.0 ycaM - - E - - - amino acid
NHGFBNON_01547 2.55e-166 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
NHGFBNON_01548 4.3e-44 - - - - - - - -
NHGFBNON_01549 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NHGFBNON_01550 0.0 - - - M - - - Domain of unknown function (DUF5011)
NHGFBNON_01551 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NHGFBNON_01552 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
NHGFBNON_01553 3.1e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NHGFBNON_01554 2.38e-225 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NHGFBNON_01555 2.8e-204 - - - EG - - - EamA-like transporter family
NHGFBNON_01556 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHGFBNON_01557 5.06e-196 - - - S - - - hydrolase
NHGFBNON_01558 7.63e-107 - - - - - - - -
NHGFBNON_01559 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
NHGFBNON_01560 1.4e-181 epsV - - S - - - glycosyl transferase family 2
NHGFBNON_01561 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
NHGFBNON_01562 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_01563 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NHGFBNON_01564 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_01565 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_01566 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NHGFBNON_01567 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NHGFBNON_01568 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_01569 2.13e-152 - - - K - - - Transcriptional regulator
NHGFBNON_01570 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHGFBNON_01571 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
NHGFBNON_01572 1.8e-293 - - - S - - - Sterol carrier protein domain
NHGFBNON_01573 3.48e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NHGFBNON_01574 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NHGFBNON_01575 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NHGFBNON_01576 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
NHGFBNON_01577 2.28e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NHGFBNON_01578 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NHGFBNON_01579 2.96e-41 - - - S - - - Pentapeptide repeats (8 copies)
NHGFBNON_01580 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NHGFBNON_01581 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NHGFBNON_01582 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NHGFBNON_01584 1.21e-69 - - - - - - - -
NHGFBNON_01585 1.52e-151 - - - - - - - -
NHGFBNON_01586 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
NHGFBNON_01587 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NHGFBNON_01588 4.79e-13 - - - - - - - -
NHGFBNON_01589 1.4e-65 - - - - - - - -
NHGFBNON_01590 1.02e-113 - - - - - - - -
NHGFBNON_01591 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
NHGFBNON_01592 8.93e-47 - - - - - - - -
NHGFBNON_01593 2.7e-104 usp5 - - T - - - universal stress protein
NHGFBNON_01594 5.12e-212 - - - K - - - LysR substrate binding domain
NHGFBNON_01595 6.36e-130 - - - - - - - -
NHGFBNON_01596 3.7e-30 - - - - - - - -
NHGFBNON_01597 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHGFBNON_01598 6.48e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHGFBNON_01599 8.48e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHGFBNON_01600 3.68e-107 - - - - - - - -
NHGFBNON_01601 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NHGFBNON_01602 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHGFBNON_01603 3.29e-162 - - - T - - - Putative diguanylate phosphodiesterase
NHGFBNON_01604 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
NHGFBNON_01605 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NHGFBNON_01606 2e-52 - - - S - - - Cytochrome B5
NHGFBNON_01607 0.0 - - - - - - - -
NHGFBNON_01608 5.86e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NHGFBNON_01609 1.58e-203 - - - I - - - alpha/beta hydrolase fold
NHGFBNON_01610 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
NHGFBNON_01611 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NHGFBNON_01612 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
NHGFBNON_01613 2.84e-266 - - - EGP - - - Major facilitator Superfamily
NHGFBNON_01614 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
NHGFBNON_01615 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NHGFBNON_01616 4.68e-190 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NHGFBNON_01617 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NHGFBNON_01618 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_01619 1.48e-167 - - - M - - - Phosphotransferase enzyme family
NHGFBNON_01620 7.2e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NHGFBNON_01621 2.81e-134 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NHGFBNON_01622 4.36e-197 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NHGFBNON_01623 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHGFBNON_01624 8.85e-141 - - - K - - - Transcriptional regulator (TetR family)
NHGFBNON_01625 1.58e-230 yhgE - - V ko:K01421 - ko00000 domain protein
NHGFBNON_01628 1.51e-312 - - - EGP - - - Major Facilitator
NHGFBNON_01629 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_01630 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_01632 1.8e-249 - - - C - - - Aldo/keto reductase family
NHGFBNON_01633 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
NHGFBNON_01634 2.17e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NHGFBNON_01635 5.52e-133 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NHGFBNON_01636 1.69e-30 - - - - - - - -
NHGFBNON_01637 1.03e-40 - - - - - - - -
NHGFBNON_01638 7.47e-164 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NHGFBNON_01639 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NHGFBNON_01640 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
NHGFBNON_01641 2.21e-46 - - - - - - - -
NHGFBNON_01642 1.38e-192 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NHGFBNON_01643 1.66e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NHGFBNON_01644 1.64e-130 - - - GM - - - NAD(P)H-binding
NHGFBNON_01645 1.83e-201 - - - K - - - LysR substrate binding domain
NHGFBNON_01646 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
NHGFBNON_01647 1.1e-144 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
NHGFBNON_01648 2.81e-64 - - - - - - - -
NHGFBNON_01649 2.8e-49 - - - - - - - -
NHGFBNON_01650 6.25e-112 yvbK - - K - - - GNAT family
NHGFBNON_01651 8.4e-112 - - - - - - - -
NHGFBNON_01652 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NHGFBNON_01653 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NHGFBNON_01654 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHGFBNON_01655 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NHGFBNON_01656 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
NHGFBNON_01657 1.11e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHGFBNON_01658 4.25e-227 - - - EG - - - EamA-like transporter family
NHGFBNON_01659 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NHGFBNON_01660 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NHGFBNON_01661 5e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NHGFBNON_01662 1.49e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHGFBNON_01663 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
NHGFBNON_01664 3.77e-84 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
NHGFBNON_01665 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHGFBNON_01666 1.83e-112 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NHGFBNON_01667 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NHGFBNON_01668 0.0 levR - - K - - - Sigma-54 interaction domain
NHGFBNON_01669 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
NHGFBNON_01670 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NHGFBNON_01671 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NHGFBNON_01672 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NHGFBNON_01673 5.27e-210 - - - G - - - Peptidase_C39 like family
NHGFBNON_01675 4.34e-31 - - - - - - - -
NHGFBNON_01679 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHGFBNON_01680 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NHGFBNON_01681 7.89e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NHGFBNON_01682 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NHGFBNON_01683 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
NHGFBNON_01684 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NHGFBNON_01685 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHGFBNON_01686 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHGFBNON_01687 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NHGFBNON_01688 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NHGFBNON_01689 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHGFBNON_01690 2.65e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHGFBNON_01691 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NHGFBNON_01692 1.59e-247 ysdE - - P - - - Citrate transporter
NHGFBNON_01693 1.53e-212 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
NHGFBNON_01694 2.78e-71 - - - S - - - Cupin domain
NHGFBNON_01695 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
NHGFBNON_01699 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
NHGFBNON_01700 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NHGFBNON_01702 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NHGFBNON_01703 7.43e-130 padR - - K - - - Virulence activator alpha C-term
NHGFBNON_01704 2.51e-103 - - - T - - - Universal stress protein family
NHGFBNON_01705 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NHGFBNON_01706 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NHGFBNON_01707 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHGFBNON_01708 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHGFBNON_01709 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
NHGFBNON_01710 2.54e-31 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NHGFBNON_01711 3.19e-62 - - - - - - - -
NHGFBNON_01712 8.74e-155 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
NHGFBNON_01714 1.53e-222 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NHGFBNON_01715 3e-08 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_01716 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHGFBNON_01717 6.08e-179 - - - K - - - DeoR C terminal sensor domain
NHGFBNON_01718 8.35e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
NHGFBNON_01719 6.57e-311 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NHGFBNON_01720 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NHGFBNON_01721 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NHGFBNON_01722 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NHGFBNON_01723 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NHGFBNON_01724 1.45e-162 - - - S - - - Membrane
NHGFBNON_01725 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
NHGFBNON_01726 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NHGFBNON_01727 5.03e-95 - - - K - - - Transcriptional regulator
NHGFBNON_01728 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NHGFBNON_01729 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NHGFBNON_01731 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NHGFBNON_01732 1.48e-95 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NHGFBNON_01733 7.24e-23 - - - - - - - -
NHGFBNON_01734 2.56e-261 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHGFBNON_01735 3.67e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHGFBNON_01736 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
NHGFBNON_01737 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
NHGFBNON_01738 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
NHGFBNON_01739 1.06e-16 - - - - - - - -
NHGFBNON_01740 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
NHGFBNON_01741 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
NHGFBNON_01742 5.6e-292 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
NHGFBNON_01743 5.23e-160 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NHGFBNON_01744 3.44e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_01745 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHGFBNON_01746 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
NHGFBNON_01747 8.71e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHGFBNON_01748 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NHGFBNON_01749 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NHGFBNON_01750 7.06e-93 - - - S - - - Protein of unknown function (DUF1694)
NHGFBNON_01751 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NHGFBNON_01752 2.05e-159 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
NHGFBNON_01753 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHGFBNON_01754 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_01755 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NHGFBNON_01756 7.47e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NHGFBNON_01757 1.54e-310 - - - K ko:K02538 - ko00000,ko03000 PRD domain
NHGFBNON_01758 2.28e-08 - - - H - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHGFBNON_01759 1.91e-98 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHGFBNON_01760 6.25e-63 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NHGFBNON_01761 3.64e-224 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
NHGFBNON_01762 4.66e-164 alsE - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
NHGFBNON_01763 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHGFBNON_01764 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHGFBNON_01765 2.58e-186 yxeH - - S - - - hydrolase
NHGFBNON_01766 2.83e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHGFBNON_01768 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NHGFBNON_01769 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NHGFBNON_01770 3.1e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NHGFBNON_01771 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NHGFBNON_01772 1.07e-202 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NHGFBNON_01773 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_01774 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_01775 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_01776 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NHGFBNON_01777 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHGFBNON_01778 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_01779 0.0 - - - S - - - Putative threonine/serine exporter
NHGFBNON_01780 1.54e-248 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHGFBNON_01781 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NHGFBNON_01782 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
NHGFBNON_01783 5.07e-157 ydgI - - C - - - Nitroreductase family
NHGFBNON_01784 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NHGFBNON_01785 4.06e-211 - - - S - - - KR domain
NHGFBNON_01786 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHGFBNON_01787 2.49e-95 - - - C - - - FMN binding
NHGFBNON_01788 1.46e-204 - - - K - - - LysR family
NHGFBNON_01789 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NHGFBNON_01790 0.0 - - - C - - - FMN_bind
NHGFBNON_01791 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
NHGFBNON_01792 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
NHGFBNON_01793 1.91e-156 pnb - - C - - - nitroreductase
NHGFBNON_01794 2e-155 ung2 - - L - - - Uracil-DNA glycosylase
NHGFBNON_01795 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NHGFBNON_01796 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
NHGFBNON_01797 2e-123 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_01798 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHGFBNON_01799 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NHGFBNON_01800 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NHGFBNON_01801 3.54e-195 yycI - - S - - - YycH protein
NHGFBNON_01802 3.55e-313 yycH - - S - - - YycH protein
NHGFBNON_01803 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHGFBNON_01804 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NHGFBNON_01806 2.54e-50 - - - - - - - -
NHGFBNON_01807 1.78e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
NHGFBNON_01808 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
NHGFBNON_01809 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
NHGFBNON_01810 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NHGFBNON_01811 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
NHGFBNON_01813 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NHGFBNON_01814 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHGFBNON_01815 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NHGFBNON_01816 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NHGFBNON_01817 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHGFBNON_01818 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHGFBNON_01820 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NHGFBNON_01822 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHGFBNON_01823 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHGFBNON_01824 4.96e-289 yttB - - EGP - - - Major Facilitator
NHGFBNON_01825 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NHGFBNON_01826 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NHGFBNON_01827 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NHGFBNON_01828 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHGFBNON_01829 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHGFBNON_01830 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NHGFBNON_01831 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHGFBNON_01832 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHGFBNON_01833 2.95e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHGFBNON_01834 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NHGFBNON_01835 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHGFBNON_01836 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHGFBNON_01837 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHGFBNON_01838 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHGFBNON_01839 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NHGFBNON_01840 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
NHGFBNON_01841 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
NHGFBNON_01842 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHGFBNON_01843 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHGFBNON_01844 3.74e-143 - - - S - - - Cell surface protein
NHGFBNON_01845 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
NHGFBNON_01847 0.0 - - - - - - - -
NHGFBNON_01848 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHGFBNON_01850 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NHGFBNON_01851 1.43e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NHGFBNON_01852 6.95e-204 degV1 - - S - - - DegV family
NHGFBNON_01853 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
NHGFBNON_01854 1.13e-182 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NHGFBNON_01855 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NHGFBNON_01856 6.57e-195 gntR - - K - - - rpiR family
NHGFBNON_01857 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_01858 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_01859 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NHGFBNON_01860 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_01861 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHGFBNON_01862 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NHGFBNON_01863 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHGFBNON_01864 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHGFBNON_01865 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHGFBNON_01866 9.48e-263 camS - - S - - - sex pheromone
NHGFBNON_01867 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHGFBNON_01868 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NHGFBNON_01869 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHGFBNON_01870 1.13e-120 yebE - - S - - - UPF0316 protein
NHGFBNON_01871 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHGFBNON_01872 2.8e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NHGFBNON_01873 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NHGFBNON_01874 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NHGFBNON_01875 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHGFBNON_01876 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
NHGFBNON_01877 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHGFBNON_01878 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NHGFBNON_01879 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NHGFBNON_01880 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NHGFBNON_01881 0.0 - - - S ko:K06889 - ko00000 Alpha beta
NHGFBNON_01882 6.07e-33 - - - - - - - -
NHGFBNON_01883 1.49e-121 - - - K - - - transcriptional regulator
NHGFBNON_01884 0.0 - - - EGP - - - Major Facilitator
NHGFBNON_01885 1.14e-193 - - - O - - - Band 7 protein
NHGFBNON_01886 1.73e-113 - - - S - - - Protein of unknown function with HXXEE motif
NHGFBNON_01887 2.19e-07 - - - K - - - transcriptional regulator
NHGFBNON_01888 1.48e-71 - - - - - - - -
NHGFBNON_01889 2.02e-39 - - - - - - - -
NHGFBNON_01890 8e-275 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NHGFBNON_01891 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
NHGFBNON_01892 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NHGFBNON_01893 2.05e-55 - - - - - - - -
NHGFBNON_01894 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
NHGFBNON_01895 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
NHGFBNON_01896 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
NHGFBNON_01897 7.27e-211 - - - I - - - Diacylglycerol kinase catalytic domain
NHGFBNON_01898 1.51e-48 - - - - - - - -
NHGFBNON_01899 5.79e-21 - - - - - - - -
NHGFBNON_01900 2.22e-55 - - - S - - - transglycosylase associated protein
NHGFBNON_01901 4e-40 - - - S - - - CsbD-like
NHGFBNON_01902 1.06e-53 - - - - - - - -
NHGFBNON_01903 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHGFBNON_01904 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NHGFBNON_01905 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHGFBNON_01906 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NHGFBNON_01907 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
NHGFBNON_01908 1.25e-66 - - - - - - - -
NHGFBNON_01909 3.23e-58 - - - - - - - -
NHGFBNON_01910 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHGFBNON_01911 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NHGFBNON_01912 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NHGFBNON_01913 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NHGFBNON_01914 2.18e-146 - - - S - - - Domain of unknown function (DUF4767)
NHGFBNON_01915 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NHGFBNON_01916 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NHGFBNON_01917 1.31e-244 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NHGFBNON_01918 4.98e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHGFBNON_01919 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NHGFBNON_01920 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NHGFBNON_01921 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NHGFBNON_01922 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NHGFBNON_01923 1.46e-106 ypmB - - S - - - protein conserved in bacteria
NHGFBNON_01924 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NHGFBNON_01925 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NHGFBNON_01926 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
NHGFBNON_01928 7.74e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHGFBNON_01929 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_01930 1.3e-202 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NHGFBNON_01931 5.32e-109 - - - T - - - Universal stress protein family
NHGFBNON_01932 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_01933 3.28e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHGFBNON_01934 3.98e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NHGFBNON_01935 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NHGFBNON_01936 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHGFBNON_01937 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
NHGFBNON_01938 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHGFBNON_01940 4.11e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NHGFBNON_01942 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NHGFBNON_01943 7.86e-96 - - - S - - - SnoaL-like domain
NHGFBNON_01944 3.2e-254 - - - M - - - Glycosyltransferase, group 2 family protein
NHGFBNON_01945 1.65e-265 mccF - - V - - - LD-carboxypeptidase
NHGFBNON_01946 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
NHGFBNON_01947 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
NHGFBNON_01948 1.44e-234 - - - V - - - LD-carboxypeptidase
NHGFBNON_01949 1.99e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NHGFBNON_01950 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NHGFBNON_01951 1.37e-248 - - - - - - - -
NHGFBNON_01952 1.5e-186 - - - S - - - hydrolase activity, acting on ester bonds
NHGFBNON_01953 1.47e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
NHGFBNON_01954 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NHGFBNON_01955 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
NHGFBNON_01956 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NHGFBNON_01957 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHGFBNON_01958 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHGFBNON_01959 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHGFBNON_01960 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NHGFBNON_01961 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NHGFBNON_01962 0.0 - - - S - - - Bacterial membrane protein, YfhO
NHGFBNON_01963 2.01e-145 - - - G - - - Phosphoglycerate mutase family
NHGFBNON_01964 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NHGFBNON_01966 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
NHGFBNON_01967 9.93e-91 - - - S - - - LuxR family transcriptional regulator
NHGFBNON_01968 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
NHGFBNON_01970 1.87e-117 - - - F - - - NUDIX domain
NHGFBNON_01971 6.19e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_01972 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NHGFBNON_01973 0.0 FbpA - - K - - - Fibronectin-binding protein
NHGFBNON_01974 1.97e-87 - - - K - - - Transcriptional regulator
NHGFBNON_01975 1.11e-205 - - - S - - - EDD domain protein, DegV family
NHGFBNON_01976 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
NHGFBNON_01977 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
NHGFBNON_01978 2.38e-39 - - - - - - - -
NHGFBNON_01979 1.23e-63 - - - - - - - -
NHGFBNON_01980 2.32e-189 - - - C - - - Domain of unknown function (DUF4931)
NHGFBNON_01981 4.93e-267 pmrB - - EGP - - - Major Facilitator Superfamily
NHGFBNON_01983 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
NHGFBNON_01984 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
NHGFBNON_01985 1.05e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
NHGFBNON_01986 1.23e-311 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NHGFBNON_01987 1.85e-174 - - - - - - - -
NHGFBNON_01988 7.79e-78 - - - - - - - -
NHGFBNON_01989 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NHGFBNON_01990 1.12e-288 - - - - - - - -
NHGFBNON_01991 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NHGFBNON_01992 1.47e-243 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NHGFBNON_01993 1.66e-249 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHGFBNON_01994 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHGFBNON_01995 1.34e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NHGFBNON_01996 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_01997 7.91e-305 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NHGFBNON_01998 3.65e-62 - - - - - - - -
NHGFBNON_01999 4.8e-310 - - - M - - - Glycosyl transferase family group 2
NHGFBNON_02000 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHGFBNON_02001 2.08e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
NHGFBNON_02002 1.07e-43 - - - S - - - YozE SAM-like fold
NHGFBNON_02003 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHGFBNON_02004 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NHGFBNON_02005 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NHGFBNON_02006 3.82e-228 - - - K - - - Transcriptional regulator
NHGFBNON_02007 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHGFBNON_02008 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHGFBNON_02009 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHGFBNON_02010 7.34e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NHGFBNON_02011 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHGFBNON_02012 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHGFBNON_02013 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NHGFBNON_02014 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHGFBNON_02015 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHGFBNON_02016 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NHGFBNON_02017 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHGFBNON_02018 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHGFBNON_02020 7.29e-292 XK27_05470 - - E - - - Methionine synthase
NHGFBNON_02021 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
NHGFBNON_02022 5.85e-159 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NHGFBNON_02023 4.28e-253 XK27_00915 - - C - - - Luciferase-like monooxygenase
NHGFBNON_02024 0.0 qacA - - EGP - - - Major Facilitator
NHGFBNON_02025 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NHGFBNON_02026 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
NHGFBNON_02027 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NHGFBNON_02028 5.91e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NHGFBNON_02029 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
NHGFBNON_02030 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHGFBNON_02031 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHGFBNON_02032 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02033 6.46e-109 - - - - - - - -
NHGFBNON_02034 3.65e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHGFBNON_02035 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHGFBNON_02036 7.48e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NHGFBNON_02037 5.83e-291 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NHGFBNON_02038 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHGFBNON_02039 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NHGFBNON_02040 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NHGFBNON_02041 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NHGFBNON_02042 1.25e-39 - - - M - - - Lysin motif
NHGFBNON_02043 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NHGFBNON_02044 2.28e-250 - - - S - - - Helix-turn-helix domain
NHGFBNON_02045 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHGFBNON_02046 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NHGFBNON_02047 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHGFBNON_02048 5.83e-175 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHGFBNON_02049 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHGFBNON_02050 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NHGFBNON_02051 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
NHGFBNON_02052 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
NHGFBNON_02053 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NHGFBNON_02054 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHGFBNON_02055 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NHGFBNON_02056 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
NHGFBNON_02057 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NHGFBNON_02058 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NHGFBNON_02059 1.61e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHGFBNON_02060 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NHGFBNON_02061 2.89e-294 - - - M - - - O-Antigen ligase
NHGFBNON_02062 4.18e-164 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NHGFBNON_02063 1.71e-212 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_02064 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_02065 1.97e-110 - - - S - - - Pfam:DUF3816
NHGFBNON_02066 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHGFBNON_02067 1.27e-143 - - - - - - - -
NHGFBNON_02068 1.53e-243 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NHGFBNON_02069 3.84e-185 - - - S - - - Peptidase_C39 like family
NHGFBNON_02070 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
NHGFBNON_02071 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NHGFBNON_02072 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
NHGFBNON_02073 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHGFBNON_02074 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NHGFBNON_02075 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NHGFBNON_02076 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02077 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NHGFBNON_02078 2e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NHGFBNON_02079 3.55e-127 ywjB - - H - - - RibD C-terminal domain
NHGFBNON_02080 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHGFBNON_02081 9.01e-155 - - - S - - - Membrane
NHGFBNON_02082 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
NHGFBNON_02083 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NHGFBNON_02084 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NHGFBNON_02085 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHGFBNON_02086 2.2e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHGFBNON_02087 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHGFBNON_02088 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
NHGFBNON_02089 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
NHGFBNON_02090 1.2e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHGFBNON_02091 6.68e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHGFBNON_02092 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NHGFBNON_02093 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
NHGFBNON_02094 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
NHGFBNON_02095 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
NHGFBNON_02096 2.09e-83 - - - - - - - -
NHGFBNON_02097 1.52e-199 estA - - S - - - Putative esterase
NHGFBNON_02098 3.15e-173 - - - K - - - UTRA domain
NHGFBNON_02099 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_02100 1.62e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NHGFBNON_02101 1.69e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
NHGFBNON_02102 7.57e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NHGFBNON_02103 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHGFBNON_02104 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NHGFBNON_02105 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHGFBNON_02106 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NHGFBNON_02107 1.77e-136 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHGFBNON_02108 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
NHGFBNON_02109 1.15e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NHGFBNON_02110 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
NHGFBNON_02111 5.51e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHGFBNON_02112 1.19e-289 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NHGFBNON_02113 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NHGFBNON_02114 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
NHGFBNON_02115 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
NHGFBNON_02116 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NHGFBNON_02117 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
NHGFBNON_02118 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NHGFBNON_02119 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NHGFBNON_02120 1.34e-52 - - - - - - - -
NHGFBNON_02121 2.37e-107 uspA - - T - - - universal stress protein
NHGFBNON_02122 1.2e-262 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NHGFBNON_02123 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
NHGFBNON_02124 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NHGFBNON_02125 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NHGFBNON_02126 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NHGFBNON_02127 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
NHGFBNON_02128 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NHGFBNON_02129 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NHGFBNON_02130 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_02131 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHGFBNON_02132 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NHGFBNON_02133 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NHGFBNON_02134 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
NHGFBNON_02135 5.3e-58 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NHGFBNON_02136 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NHGFBNON_02137 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NHGFBNON_02138 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHGFBNON_02139 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NHGFBNON_02140 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHGFBNON_02141 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHGFBNON_02142 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHGFBNON_02143 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHGFBNON_02144 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHGFBNON_02145 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHGFBNON_02146 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NHGFBNON_02147 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NHGFBNON_02148 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHGFBNON_02149 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHGFBNON_02150 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHGFBNON_02151 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHGFBNON_02152 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHGFBNON_02153 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NHGFBNON_02154 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NHGFBNON_02155 1.06e-174 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NHGFBNON_02156 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NHGFBNON_02157 2.65e-245 ampC - - V - - - Beta-lactamase
NHGFBNON_02158 2.1e-41 - - - - - - - -
NHGFBNON_02159 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NHGFBNON_02160 1.33e-77 - - - - - - - -
NHGFBNON_02161 5.98e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHGFBNON_02162 1.24e-138 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NHGFBNON_02163 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHGFBNON_02165 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02166 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NHGFBNON_02167 1.46e-299 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NHGFBNON_02168 7.37e-103 - - - K - - - transcriptional regulator, MerR family
NHGFBNON_02169 2.27e-98 yphH - - S - - - Cupin domain
NHGFBNON_02170 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NHGFBNON_02171 3.63e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGFBNON_02172 6.47e-268 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NHGFBNON_02173 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02174 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NHGFBNON_02175 4.96e-88 - - - M - - - LysM domain
NHGFBNON_02177 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHGFBNON_02178 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
NHGFBNON_02179 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NHGFBNON_02180 4.38e-222 - - - S - - - Conserved hypothetical protein 698
NHGFBNON_02181 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NHGFBNON_02182 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
NHGFBNON_02183 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NHGFBNON_02184 8.43e-162 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NHGFBNON_02185 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
NHGFBNON_02186 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHGFBNON_02187 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NHGFBNON_02188 1.4e-162 - - - S - - - DJ-1/PfpI family
NHGFBNON_02189 7.65e-121 yfbM - - K - - - FR47-like protein
NHGFBNON_02190 4.28e-195 - - - EG - - - EamA-like transporter family
NHGFBNON_02191 4.73e-143 - - - S - - - Protein of unknown function
NHGFBNON_02192 1.15e-07 - - - S - - - Protein of unknown function
NHGFBNON_02193 0.0 fusA1 - - J - - - elongation factor G
NHGFBNON_02194 1.34e-151 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHGFBNON_02195 1.67e-220 - - - K - - - WYL domain
NHGFBNON_02196 3.06e-165 - - - F - - - glutamine amidotransferase
NHGFBNON_02197 1.65e-106 - - - S - - - ASCH
NHGFBNON_02198 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
NHGFBNON_02199 3.97e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NHGFBNON_02200 1.62e-277 - - - T - - - diguanylate cyclase
NHGFBNON_02201 1.11e-45 - - - - - - - -
NHGFBNON_02202 2.29e-48 - - - - - - - -
NHGFBNON_02203 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
NHGFBNON_02204 1.37e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
NHGFBNON_02205 1.65e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_02207 2.68e-32 - - - - - - - -
NHGFBNON_02208 1.9e-176 - - - F - - - NUDIX domain
NHGFBNON_02209 1.96e-273 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
NHGFBNON_02210 1.31e-64 - - - - - - - -
NHGFBNON_02211 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
NHGFBNON_02213 1.26e-218 - - - EG - - - EamA-like transporter family
NHGFBNON_02214 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NHGFBNON_02215 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NHGFBNON_02216 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NHGFBNON_02217 0.0 yclK - - T - - - Histidine kinase
NHGFBNON_02218 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
NHGFBNON_02219 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
NHGFBNON_02220 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NHGFBNON_02221 2.1e-33 - - - - - - - -
NHGFBNON_02222 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02223 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHGFBNON_02224 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
NHGFBNON_02225 4.63e-24 - - - - - - - -
NHGFBNON_02226 2.16e-26 - - - - - - - -
NHGFBNON_02227 9.35e-24 - - - - - - - -
NHGFBNON_02228 9.51e-135 - - - - - - - -
NHGFBNON_02229 0.0 icaA - - M - - - Glycosyl transferase family group 2
NHGFBNON_02230 0.0 - - - - - - - -
NHGFBNON_02231 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NHGFBNON_02232 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NHGFBNON_02233 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NHGFBNON_02234 4.98e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NHGFBNON_02235 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHGFBNON_02236 4.27e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NHGFBNON_02237 2.56e-162 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NHGFBNON_02238 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NHGFBNON_02239 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NHGFBNON_02240 5.09e-241 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NHGFBNON_02241 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NHGFBNON_02242 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHGFBNON_02243 3.84e-262 - - - EGP - - - Major Facilitator Superfamily
NHGFBNON_02244 5.25e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHGFBNON_02245 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHGFBNON_02246 5.89e-204 - - - S - - - Tetratricopeptide repeat
NHGFBNON_02247 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHGFBNON_02248 3.75e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHGFBNON_02249 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHGFBNON_02250 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NHGFBNON_02251 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
NHGFBNON_02252 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
NHGFBNON_02253 5.12e-31 - - - - - - - -
NHGFBNON_02254 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NHGFBNON_02255 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02256 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHGFBNON_02257 8.45e-162 epsB - - M - - - biosynthesis protein
NHGFBNON_02258 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
NHGFBNON_02259 2.25e-188 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NHGFBNON_02260 1.62e-228 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NHGFBNON_02261 5.49e-163 tuaA - - M - - - Bacterial sugar transferase
NHGFBNON_02262 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
NHGFBNON_02263 5.46e-235 cps4G - - M - - - Glycosyltransferase Family 4
NHGFBNON_02264 1.01e-292 - - - - - - - -
NHGFBNON_02265 2.39e-228 cps4I - - M - - - Glycosyltransferase like family 2
NHGFBNON_02266 0.0 cps4J - - S - - - MatE
NHGFBNON_02267 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NHGFBNON_02268 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NHGFBNON_02269 1.73e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHGFBNON_02270 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NHGFBNON_02271 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHGFBNON_02272 6.62e-62 - - - - - - - -
NHGFBNON_02273 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHGFBNON_02274 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGFBNON_02275 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
NHGFBNON_02276 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NHGFBNON_02277 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHGFBNON_02278 4.57e-135 - - - K - - - Helix-turn-helix domain
NHGFBNON_02279 1.17e-269 - - - EGP - - - Major facilitator Superfamily
NHGFBNON_02280 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
NHGFBNON_02281 4.15e-183 - - - Q - - - Methyltransferase
NHGFBNON_02282 1.75e-43 - - - - - - - -
NHGFBNON_02284 1.38e-293 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
NHGFBNON_02285 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_02286 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NHGFBNON_02287 3.66e-280 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
NHGFBNON_02288 6.27e-131 - - - L - - - Helix-turn-helix domain
NHGFBNON_02289 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
NHGFBNON_02290 1.09e-86 - - - - - - - -
NHGFBNON_02291 1.94e-97 - - - - - - - -
NHGFBNON_02292 1.1e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NHGFBNON_02293 6.4e-122 - - - - - - - -
NHGFBNON_02294 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHGFBNON_02295 7.68e-48 ynzC - - S - - - UPF0291 protein
NHGFBNON_02296 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NHGFBNON_02297 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NHGFBNON_02298 3.4e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NHGFBNON_02299 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NHGFBNON_02300 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGFBNON_02301 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NHGFBNON_02302 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NHGFBNON_02303 2.67e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHGFBNON_02304 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NHGFBNON_02305 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHGFBNON_02306 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHGFBNON_02307 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NHGFBNON_02308 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NHGFBNON_02309 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHGFBNON_02310 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHGFBNON_02311 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NHGFBNON_02312 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NHGFBNON_02313 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NHGFBNON_02314 3.28e-63 ylxQ - - J - - - ribosomal protein
NHGFBNON_02315 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHGFBNON_02316 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHGFBNON_02317 0.0 - - - G - - - Major Facilitator
NHGFBNON_02318 2.21e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHGFBNON_02319 9.84e-123 - - - - - - - -
NHGFBNON_02320 1.16e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHGFBNON_02321 3.1e-248 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NHGFBNON_02322 5.91e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHGFBNON_02323 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHGFBNON_02324 1.25e-240 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NHGFBNON_02325 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NHGFBNON_02326 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHGFBNON_02327 1.72e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHGFBNON_02328 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NHGFBNON_02329 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHGFBNON_02330 4.21e-266 pbpX2 - - V - - - Beta-lactamase
NHGFBNON_02331 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NHGFBNON_02332 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHGFBNON_02333 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NHGFBNON_02334 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHGFBNON_02335 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHGFBNON_02336 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHGFBNON_02337 1.73e-67 - - - - - - - -
NHGFBNON_02338 4.78e-65 - - - - - - - -
NHGFBNON_02339 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NHGFBNON_02340 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NHGFBNON_02341 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHGFBNON_02342 2.56e-76 - - - - - - - -
NHGFBNON_02343 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHGFBNON_02344 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHGFBNON_02345 5.97e-151 yjcF - - J - - - HAD-hyrolase-like
NHGFBNON_02346 5.35e-213 - - - G - - - Fructosamine kinase
NHGFBNON_02347 5.7e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NHGFBNON_02348 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NHGFBNON_02349 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHGFBNON_02350 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHGFBNON_02351 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHGFBNON_02352 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHGFBNON_02353 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHGFBNON_02354 3e-165 - - - C - - - Enoyl-(Acyl carrier protein) reductase
NHGFBNON_02355 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHGFBNON_02356 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NHGFBNON_02357 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NHGFBNON_02358 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NHGFBNON_02359 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHGFBNON_02360 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NHGFBNON_02361 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHGFBNON_02362 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NHGFBNON_02363 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NHGFBNON_02364 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NHGFBNON_02365 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHGFBNON_02366 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHGFBNON_02367 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NHGFBNON_02368 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02369 5.01e-254 - - - - - - - -
NHGFBNON_02370 2.48e-252 - - - - - - - -
NHGFBNON_02371 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NHGFBNON_02372 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02373 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
NHGFBNON_02374 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
NHGFBNON_02375 3.89e-94 - - - K - - - MarR family
NHGFBNON_02376 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NHGFBNON_02378 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_02379 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NHGFBNON_02380 2.08e-265 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHGFBNON_02381 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NHGFBNON_02382 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHGFBNON_02384 7.63e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NHGFBNON_02385 5.72e-207 - - - K - - - Transcriptional regulator
NHGFBNON_02386 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
NHGFBNON_02387 8.72e-147 - - - GM - - - NmrA-like family
NHGFBNON_02388 2.63e-206 - - - S - - - Alpha beta hydrolase
NHGFBNON_02389 3.69e-169 - - - K - - - Helix-turn-helix domain, rpiR family
NHGFBNON_02390 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NHGFBNON_02391 7.51e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NHGFBNON_02392 1.64e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_02393 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NHGFBNON_02394 1.55e-07 - - - K - - - transcriptional regulator
NHGFBNON_02395 3.08e-271 - - - S - - - membrane
NHGFBNON_02396 6.13e-105 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_02397 0.0 - - - S - - - Zinc finger, swim domain protein
NHGFBNON_02398 8.09e-146 - - - GM - - - epimerase
NHGFBNON_02399 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
NHGFBNON_02400 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
NHGFBNON_02401 5.1e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NHGFBNON_02402 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NHGFBNON_02403 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHGFBNON_02404 1.12e-265 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NHGFBNON_02405 4.38e-102 - - - K - - - Transcriptional regulator
NHGFBNON_02406 8.43e-302 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
NHGFBNON_02407 1.09e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHGFBNON_02408 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NHGFBNON_02409 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
NHGFBNON_02410 6.09e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NHGFBNON_02411 5.78e-268 - - - - - - - -
NHGFBNON_02412 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_02413 1.94e-83 - - - P - - - Rhodanese Homology Domain
NHGFBNON_02414 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NHGFBNON_02415 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHGFBNON_02416 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
NHGFBNON_02417 7.9e-289 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHGFBNON_02418 6.56e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHGFBNON_02419 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHGFBNON_02420 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NHGFBNON_02421 2.34e-284 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NHGFBNON_02422 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHGFBNON_02423 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NHGFBNON_02424 5.6e-41 - - - - - - - -
NHGFBNON_02425 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NHGFBNON_02426 2.5e-132 - - - L - - - Integrase
NHGFBNON_02427 3.4e-85 - - - K - - - Winged helix DNA-binding domain
NHGFBNON_02428 1.08e-60 gpG - - - - - - -
NHGFBNON_02429 7.62e-42 gpG - - - - - - -
NHGFBNON_02430 2.41e-109 - - - S - - - Domain of unknown function (DUF4355)
NHGFBNON_02431 6.96e-20 - - - S - - - Transglycosylase associated protein
NHGFBNON_02432 3.12e-309 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHGFBNON_02433 7.86e-242 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
NHGFBNON_02434 3.03e-164 - - - EGP ko:K08164 - ko00000,ko02000 Transporter
NHGFBNON_02435 7.54e-66 - - - L - - - Transposase and inactivated derivatives, IS30 family
NHGFBNON_02436 1.95e-45 ydaT - - - - - - -
NHGFBNON_02438 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NHGFBNON_02440 1.76e-86 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_02441 8.08e-180 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NHGFBNON_02442 6.62e-197 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NHGFBNON_02443 1.41e-129 tnpR - - L - - - Resolvase, N terminal domain
NHGFBNON_02444 4.05e-148 prrC - - - - - - -
NHGFBNON_02445 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NHGFBNON_02446 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NHGFBNON_02447 3.97e-84 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
NHGFBNON_02448 3.76e-249 - - - L - - - Psort location Cytoplasmic, score
NHGFBNON_02449 1.85e-44 - - - - - - - -
NHGFBNON_02450 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NHGFBNON_02451 0.0 traA - - L - - - MobA MobL family protein
NHGFBNON_02453 0.0 - - - S - - - MucBP domain
NHGFBNON_02455 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
NHGFBNON_02456 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
NHGFBNON_02457 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHGFBNON_02458 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NHGFBNON_02459 1.24e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NHGFBNON_02460 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
NHGFBNON_02461 2.65e-214 mleR - - K - - - LysR family
NHGFBNON_02462 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NHGFBNON_02463 9.09e-213 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NHGFBNON_02464 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NHGFBNON_02465 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
NHGFBNON_02466 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
NHGFBNON_02467 0.0 - - - S - - - ABC transporter, ATP-binding protein
NHGFBNON_02468 1.67e-182 - - - U ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_02469 4.82e-193 - - - U ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_02470 2.6e-315 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHGFBNON_02471 3.63e-270 msmK2 - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHGFBNON_02472 4.97e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NHGFBNON_02476 5.81e-24 - - - N - - - Cell shape-determining protein MreB
NHGFBNON_02477 7.22e-256 - - - S - - - Pfam Methyltransferase
NHGFBNON_02478 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHGFBNON_02479 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHGFBNON_02480 9.32e-40 - - - - - - - -
NHGFBNON_02481 5.13e-138 mraW1 - - J - - - Putative rRNA methylase
NHGFBNON_02482 6.19e-162 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NHGFBNON_02483 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NHGFBNON_02484 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NHGFBNON_02485 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NHGFBNON_02486 9.06e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHGFBNON_02487 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NHGFBNON_02488 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
NHGFBNON_02489 1.24e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
NHGFBNON_02490 2.27e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHGFBNON_02491 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_02492 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHGFBNON_02493 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NHGFBNON_02494 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
NHGFBNON_02495 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHGFBNON_02496 4.23e-315 XK27_06930 - - V ko:K01421 - ko00000 domain protein
NHGFBNON_02498 8.55e-163 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NHGFBNON_02499 1.77e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHGFBNON_02500 6.05e-225 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
NHGFBNON_02502 3.86e-195 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHGFBNON_02503 2.12e-84 - - - K - - - helix_turn_helix, mercury resistance
NHGFBNON_02504 5.48e-150 - - - GM - - - NAD(P)H-binding
NHGFBNON_02505 1.55e-203 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHGFBNON_02506 4.65e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NHGFBNON_02507 7.83e-140 - - - - - - - -
NHGFBNON_02508 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHGFBNON_02509 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHGFBNON_02510 5.37e-74 - - - - - - - -
NHGFBNON_02511 4.56e-78 - - - - - - - -
NHGFBNON_02512 1.06e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02513 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_02514 8.82e-119 - - - - - - - -
NHGFBNON_02515 7.12e-62 - - - - - - - -
NHGFBNON_02516 0.0 uvrA2 - - L - - - ABC transporter
NHGFBNON_02518 1.43e-271 - - - S - - - Phage integrase family
NHGFBNON_02519 5.8e-46 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NHGFBNON_02520 3.18e-77 - - - L - - - Transposase
NHGFBNON_02521 3.03e-50 - - - S - - - Protein of unknown function (DUF4065)
NHGFBNON_02527 6.22e-48 - - - S - - - Pfam:Peptidase_M78
NHGFBNON_02528 3.49e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
NHGFBNON_02532 1.13e-72 - - - S - - - ORF6C domain
NHGFBNON_02535 3.83e-68 - - - S - - - Domain of unknown function (DUF771)
NHGFBNON_02537 7.64e-20 - - - - - - - -
NHGFBNON_02540 1.37e-134 - - - S - - - Putative HNHc nuclease
NHGFBNON_02541 1.57e-94 - - - L - - - DnaD domain protein
NHGFBNON_02542 9.91e-170 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NHGFBNON_02544 3e-61 - - - - - - - -
NHGFBNON_02546 4.33e-05 - - - - - - - -
NHGFBNON_02547 1.73e-15 - - - S - - - YopX protein
NHGFBNON_02548 4.7e-42 - - - - - - - -
NHGFBNON_02549 2.28e-25 - - - - - - - -
NHGFBNON_02550 2.19e-82 - - - S - - - Transcriptional regulator, RinA family
NHGFBNON_02554 2.95e-117 - - - L - - - HNH nucleases
NHGFBNON_02557 8.75e-101 - - - S - - - Phage terminase, small subunit
NHGFBNON_02558 0.0 - - - S - - - Phage Terminase
NHGFBNON_02559 1.64e-35 - - - S - - - Protein of unknown function (DUF1056)
NHGFBNON_02560 6.4e-280 - - - S - - - Phage portal protein
NHGFBNON_02561 2.34e-156 - - - S - - - Clp protease
NHGFBNON_02562 4.52e-266 - - - S - - - Phage capsid family
NHGFBNON_02563 9.27e-66 - - - S - - - Phage gp6-like head-tail connector protein
NHGFBNON_02564 3.45e-32 - - - S - - - Phage head-tail joining protein
NHGFBNON_02565 5.38e-50 - - - - - - - -
NHGFBNON_02567 6.37e-92 - - - S - - - Phage tail tube protein
NHGFBNON_02569 5.58e-06 - - - - - - - -
NHGFBNON_02570 0.0 - - - S - - - peptidoglycan catabolic process
NHGFBNON_02571 1.15e-297 - - - S - - - Phage tail protein
NHGFBNON_02572 0.0 - - - S - - - Phage minor structural protein
NHGFBNON_02573 1.45e-126 - - - - - - - -
NHGFBNON_02576 1.31e-107 - - - - - - - -
NHGFBNON_02577 1.68e-33 - - - - - - - -
NHGFBNON_02578 4.46e-255 - - - M - - - Glycosyl hydrolases family 25
NHGFBNON_02579 3.19e-50 - - - S - - - Haemolysin XhlA
NHGFBNON_02582 4.29e-87 - - - - - - - -
NHGFBNON_02583 9.03e-16 - - - - - - - -
NHGFBNON_02584 3.89e-237 - - - - - - - -
NHGFBNON_02585 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
NHGFBNON_02586 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
NHGFBNON_02587 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NHGFBNON_02588 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHGFBNON_02589 0.0 - - - S - - - Protein conserved in bacteria
NHGFBNON_02590 8.91e-293 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NHGFBNON_02591 2.24e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NHGFBNON_02592 6.91e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
NHGFBNON_02593 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
NHGFBNON_02594 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
NHGFBNON_02595 8.98e-316 dinF - - V - - - MatE
NHGFBNON_02596 1.79e-42 - - - - - - - -
NHGFBNON_02599 7.02e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
NHGFBNON_02600 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NHGFBNON_02601 3.81e-105 - - - - - - - -
NHGFBNON_02602 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NHGFBNON_02603 3.61e-137 - - - - - - - -
NHGFBNON_02604 2.57e-273 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NHGFBNON_02605 1.41e-147 yciB - - M - - - ErfK YbiS YcfS YnhG
NHGFBNON_02606 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHGFBNON_02607 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NHGFBNON_02608 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NHGFBNON_02609 2.77e-271 arcT - - E - - - Aminotransferase
NHGFBNON_02610 2.41e-101 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NHGFBNON_02611 2.43e-18 - - - - - - - -
NHGFBNON_02612 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NHGFBNON_02613 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
NHGFBNON_02614 1.05e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NHGFBNON_02615 0.0 yhaN - - L - - - AAA domain
NHGFBNON_02616 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHGFBNON_02617 1.58e-277 - - - - - - - -
NHGFBNON_02618 1.45e-234 - - - M - - - Peptidase family S41
NHGFBNON_02619 6.59e-227 - - - K - - - LysR substrate binding domain
NHGFBNON_02620 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
NHGFBNON_02621 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NHGFBNON_02622 2.57e-128 - - - - - - - -
NHGFBNON_02623 2.27e-98 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
NHGFBNON_02624 3.72e-203 - - - T - - - Histidine kinase
NHGFBNON_02625 1.73e-134 llrE - - K - - - Transcriptional regulatory protein, C terminal
NHGFBNON_02626 7.93e-79 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
NHGFBNON_02627 5.57e-168 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NHGFBNON_02628 1.18e-100 - - - S ko:K03975 - ko00000 SNARE-like domain protein
NHGFBNON_02629 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
NHGFBNON_02630 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHGFBNON_02631 1.64e-89 - - - S - - - NUDIX domain
NHGFBNON_02632 0.0 - - - S - - - membrane
NHGFBNON_02633 1.22e-217 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHGFBNON_02634 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NHGFBNON_02635 1.86e-287 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHGFBNON_02636 2.48e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHGFBNON_02637 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
NHGFBNON_02638 9.79e-37 - - - - - - - -
NHGFBNON_02639 1.03e-55 - - - - - - - -
NHGFBNON_02640 5.3e-110 - - - - - - - -
NHGFBNON_02641 6.94e-59 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
NHGFBNON_02642 3.46e-30 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHGFBNON_02643 1.23e-186 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NHGFBNON_02645 4.51e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHGFBNON_02646 2.06e-136 - - - L - - - Resolvase, N terminal domain
NHGFBNON_02647 2.61e-146 - - - L ko:K07497 - ko00000 hmm pf00665
NHGFBNON_02648 1.34e-231 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NHGFBNON_02649 7.3e-216 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NHGFBNON_02650 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHGFBNON_02651 1.67e-104 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NHGFBNON_02652 6.32e-08 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
NHGFBNON_02653 3.53e-80 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHGFBNON_02654 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
NHGFBNON_02655 7.41e-74 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_02656 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NHGFBNON_02657 8.1e-199 is18 - - L - - - Integrase core domain
NHGFBNON_02658 3.53e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
NHGFBNON_02659 1.39e-157 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NHGFBNON_02660 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NHGFBNON_02663 3.19e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHGFBNON_02666 0.0 mdr - - EGP - - - Major Facilitator
NHGFBNON_02667 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHGFBNON_02668 3.21e-155 - - - - - - - -
NHGFBNON_02669 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHGFBNON_02670 7.89e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NHGFBNON_02671 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NHGFBNON_02672 2.95e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NHGFBNON_02673 3.8e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NHGFBNON_02675 2.52e-201 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NHGFBNON_02676 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
NHGFBNON_02677 7.23e-124 - - - - - - - -
NHGFBNON_02678 3.15e-237 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
NHGFBNON_02679 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
NHGFBNON_02690 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NHGFBNON_02691 2.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHGFBNON_02692 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHGFBNON_02693 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHGFBNON_02694 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NHGFBNON_02695 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHGFBNON_02696 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
NHGFBNON_02697 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NHGFBNON_02699 7.72e-57 yabO - - J - - - S4 domain protein
NHGFBNON_02700 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NHGFBNON_02701 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHGFBNON_02702 8.29e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHGFBNON_02703 1.13e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHGFBNON_02704 0.0 - - - S - - - Putative peptidoglycan binding domain
NHGFBNON_02705 4.87e-148 - - - S - - - (CBS) domain
NHGFBNON_02706 1.3e-110 queT - - S - - - QueT transporter
NHGFBNON_02707 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHGFBNON_02708 4.66e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
NHGFBNON_02709 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NHGFBNON_02710 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHGFBNON_02711 1.04e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHGFBNON_02712 1.84e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NHGFBNON_02713 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NHGFBNON_02714 1.38e-53 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NHGFBNON_02715 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NHGFBNON_02716 4.28e-84 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NHGFBNON_02717 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHGFBNON_02718 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHGFBNON_02719 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHGFBNON_02720 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHGFBNON_02721 1.84e-189 - - - - - - - -
NHGFBNON_02722 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NHGFBNON_02723 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
NHGFBNON_02724 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NHGFBNON_02725 2.57e-274 - - - J - - - translation release factor activity
NHGFBNON_02726 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NHGFBNON_02727 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHGFBNON_02728 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHGFBNON_02729 4.01e-36 - - - - - - - -
NHGFBNON_02730 6.59e-170 - - - S - - - YheO-like PAS domain
NHGFBNON_02731 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHGFBNON_02732 1.52e-158 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NHGFBNON_02733 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
NHGFBNON_02734 7.95e-310 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHGFBNON_02735 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHGFBNON_02736 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHGFBNON_02737 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
NHGFBNON_02738 8.97e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NHGFBNON_02739 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NHGFBNON_02740 1.19e-190 yxeH - - S - - - hydrolase
NHGFBNON_02741 7.12e-178 - - - - - - - -
NHGFBNON_02742 2.59e-232 - - - S - - - DUF218 domain
NHGFBNON_02743 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHGFBNON_02744 1.15e-195 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NHGFBNON_02745 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHGFBNON_02746 2.79e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NHGFBNON_02747 5.3e-49 - - - - - - - -
NHGFBNON_02748 2.4e-56 - - - S - - - ankyrin repeats
NHGFBNON_02749 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NHGFBNON_02750 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHGFBNON_02751 1.56e-229 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
NHGFBNON_02752 1.25e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHGFBNON_02753 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
NHGFBNON_02754 7.17e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHGFBNON_02755 1.87e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHGFBNON_02756 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NHGFBNON_02757 3.91e-268 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
NHGFBNON_02758 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHGFBNON_02759 6.59e-92 - - - F - - - DNA mismatch repair protein MutT
NHGFBNON_02760 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
NHGFBNON_02761 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NHGFBNON_02762 4.65e-229 - - - - - - - -
NHGFBNON_02763 5.59e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NHGFBNON_02764 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NHGFBNON_02765 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
NHGFBNON_02766 1.23e-262 - - - - - - - -
NHGFBNON_02767 2.94e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHGFBNON_02768 3.97e-174 yecA - - K - - - Helix-turn-helix domain, rpiR family
NHGFBNON_02769 6.97e-209 - - - GK - - - ROK family
NHGFBNON_02770 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHGFBNON_02771 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_02772 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
NHGFBNON_02773 9.68e-34 - - - - - - - -
NHGFBNON_02774 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGFBNON_02775 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
NHGFBNON_02776 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NHGFBNON_02777 3.54e-182 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NHGFBNON_02778 0.0 - - - L - - - DNA helicase
NHGFBNON_02779 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
NHGFBNON_02780 3.12e-48 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
NHGFBNON_02781 1.36e-146 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02782 7.55e-143 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02783 1.89e-150 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02784 1.24e-138 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02785 6.08e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NHGFBNON_02786 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHGFBNON_02787 8.82e-32 - - - - - - - -
NHGFBNON_02788 7.89e-31 plnF - - - - - - -
NHGFBNON_02789 1.64e-166 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02790 3.38e-170 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHGFBNON_02791 5.61e-169 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHGFBNON_02792 3.92e-290 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHGFBNON_02793 1.9e-25 plnA - - - - - - -
NHGFBNON_02794 1.22e-36 - - - - - - - -
NHGFBNON_02795 2.08e-160 plnP - - S - - - CAAX protease self-immunity
NHGFBNON_02796 3.77e-289 - - - M - - - Glycosyl transferase family 2
NHGFBNON_02798 4.08e-39 - - - - - - - -
NHGFBNON_02799 8.53e-34 plnJ - - - - - - -
NHGFBNON_02800 3.29e-32 plnK - - - - - - -
NHGFBNON_02801 9.76e-153 - - - - - - - -
NHGFBNON_02802 6.24e-25 plnR - - - - - - -
NHGFBNON_02803 1.15e-43 - - - - - - - -
NHGFBNON_02805 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHGFBNON_02806 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHGFBNON_02808 8.38e-192 - - - S - - - hydrolase
NHGFBNON_02809 2.35e-212 - - - K - - - Transcriptional regulator
NHGFBNON_02810 2.3e-185 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NHGFBNON_02811 5.27e-261 - - - EGP - - - Transporter, major facilitator family protein
NHGFBNON_02812 4.56e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NHGFBNON_02813 8.5e-55 - - - - - - - -
NHGFBNON_02814 9.91e-17 - - - L - - - LXG domain of WXG superfamily
NHGFBNON_02815 2.09e-91 - - - S - - - Immunity protein 63
NHGFBNON_02816 1.18e-24 - - - - - - - -
NHGFBNON_02817 2.05e-90 - - - - - - - -
NHGFBNON_02818 4.14e-25 - - - U - - - nuclease activity
NHGFBNON_02819 8.53e-28 - - - - - - - -
NHGFBNON_02820 3.31e-52 - - - - - - - -
NHGFBNON_02821 5.89e-131 - - - S - - - ankyrin repeats
NHGFBNON_02822 1.24e-11 - - - S - - - Immunity protein 22
NHGFBNON_02823 3.15e-229 - - - - - - - -
NHGFBNON_02825 2.85e-53 - - - - - - - -
NHGFBNON_02826 7.13e-54 - - - - - - - -
NHGFBNON_02827 5.12e-87 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
NHGFBNON_02828 0.0 - - - M - - - domain protein
NHGFBNON_02829 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHGFBNON_02830 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NHGFBNON_02831 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHGFBNON_02832 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
NHGFBNON_02833 1.1e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02834 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHGFBNON_02835 1.94e-100 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
NHGFBNON_02836 4.01e-206 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGFBNON_02837 6.07e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NHGFBNON_02838 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHGFBNON_02839 1.52e-103 - - - - - - - -
NHGFBNON_02840 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NHGFBNON_02841 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NHGFBNON_02842 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NHGFBNON_02843 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NHGFBNON_02844 0.0 sufI - - Q - - - Multicopper oxidase
NHGFBNON_02845 7.16e-155 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NHGFBNON_02846 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
NHGFBNON_02847 8.95e-60 - - - - - - - -
NHGFBNON_02848 9e-227 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NHGFBNON_02849 4.08e-306 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NHGFBNON_02850 0.0 - - - P - - - Major Facilitator Superfamily
NHGFBNON_02851 2.24e-112 - - - K - - - Transcriptional regulator PadR-like family
NHGFBNON_02852 3.93e-59 - - - - - - - -
NHGFBNON_02853 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHGFBNON_02854 1.64e-198 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NHGFBNON_02855 1.1e-280 - - - - - - - -
NHGFBNON_02856 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NHGFBNON_02857 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHGFBNON_02858 9.7e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_02859 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHGFBNON_02860 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHGFBNON_02861 0.0 ydaO - - E - - - amino acid
NHGFBNON_02862 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NHGFBNON_02863 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NHGFBNON_02864 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NHGFBNON_02865 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NHGFBNON_02866 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NHGFBNON_02867 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHGFBNON_02868 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHGFBNON_02869 8.03e-256 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHGFBNON_02870 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NHGFBNON_02871 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NHGFBNON_02872 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHGFBNON_02873 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NHGFBNON_02874 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NHGFBNON_02875 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NHGFBNON_02876 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHGFBNON_02877 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHGFBNON_02878 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NHGFBNON_02879 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
NHGFBNON_02880 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NHGFBNON_02881 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHGFBNON_02882 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHGFBNON_02883 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NHGFBNON_02884 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NHGFBNON_02885 1.06e-158 - - - T - - - Putative diguanylate phosphodiesterase
NHGFBNON_02886 0.0 nox - - C - - - NADH oxidase
NHGFBNON_02887 1.29e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NHGFBNON_02888 2.45e-310 - - - - - - - -
NHGFBNON_02889 3.39e-256 - - - S - - - Protein conserved in bacteria
NHGFBNON_02890 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
NHGFBNON_02891 0.0 - - - S - - - Bacterial cellulose synthase subunit
NHGFBNON_02892 6.49e-171 - - - T - - - diguanylate cyclase activity
NHGFBNON_02893 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHGFBNON_02894 7.15e-140 yviA - - S - - - Protein of unknown function (DUF421)
NHGFBNON_02895 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
NHGFBNON_02896 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NHGFBNON_02897 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
NHGFBNON_02898 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHGFBNON_02899 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NHGFBNON_02900 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
NHGFBNON_02901 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NHGFBNON_02902 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHGFBNON_02903 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHGFBNON_02904 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHGFBNON_02905 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHGFBNON_02906 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NHGFBNON_02907 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
NHGFBNON_02908 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NHGFBNON_02909 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NHGFBNON_02910 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NHGFBNON_02911 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NHGFBNON_02912 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGFBNON_02913 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHGFBNON_02915 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
NHGFBNON_02916 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NHGFBNON_02917 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHGFBNON_02918 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NHGFBNON_02919 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHGFBNON_02920 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHGFBNON_02921 5.11e-171 - - - - - - - -
NHGFBNON_02922 0.0 eriC - - P ko:K03281 - ko00000 chloride
NHGFBNON_02923 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NHGFBNON_02924 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NHGFBNON_02925 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHGFBNON_02926 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHGFBNON_02927 0.0 - - - M - - - Domain of unknown function (DUF5011)
NHGFBNON_02928 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHGFBNON_02929 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02930 7.98e-137 - - - - - - - -
NHGFBNON_02931 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NHGFBNON_02932 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHGFBNON_02933 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NHGFBNON_02934 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NHGFBNON_02935 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
NHGFBNON_02936 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NHGFBNON_02937 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NHGFBNON_02938 1.71e-210 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
NHGFBNON_02939 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NHGFBNON_02940 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
NHGFBNON_02941 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_02942 6.9e-157 - - - S - - - Protein of unknown function (DUF1361)
NHGFBNON_02943 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHGFBNON_02944 2.18e-182 ybbR - - S - - - YbbR-like protein
NHGFBNON_02945 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHGFBNON_02946 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHGFBNON_02947 3.15e-158 - - - T - - - EAL domain
NHGFBNON_02948 1.33e-188 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
NHGFBNON_02949 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_02950 2.07e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NHGFBNON_02951 3.38e-70 - - - - - - - -
NHGFBNON_02952 2.49e-95 - - - - - - - -
NHGFBNON_02953 3.35e-167 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NHGFBNON_02954 1.73e-178 - - - EGP - - - Transmembrane secretion effector
NHGFBNON_02955 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NHGFBNON_02956 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHGFBNON_02957 3.39e-181 - - - - - - - -
NHGFBNON_02959 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
NHGFBNON_02960 3.88e-46 - - - - - - - -
NHGFBNON_02961 2.08e-117 - - - V - - - VanZ like family
NHGFBNON_02962 1.06e-314 - - - EGP - - - Major Facilitator
NHGFBNON_02963 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NHGFBNON_02964 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NHGFBNON_02965 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NHGFBNON_02966 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
NHGFBNON_02967 6.16e-107 - - - K - - - Transcriptional regulator
NHGFBNON_02968 1.36e-27 - - - - - - - -
NHGFBNON_02969 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NHGFBNON_02970 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NHGFBNON_02971 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NHGFBNON_02972 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NHGFBNON_02973 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NHGFBNON_02974 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHGFBNON_02975 0.0 oatA - - I - - - Acyltransferase
NHGFBNON_02976 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHGFBNON_02977 1.89e-90 - - - O - - - OsmC-like protein
NHGFBNON_02978 1.09e-60 - - - - - - - -
NHGFBNON_02979 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NHGFBNON_02980 6.12e-115 - - - - - - - -
NHGFBNON_02981 5.24e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NHGFBNON_02982 1.24e-94 - - - F - - - Nudix hydrolase
NHGFBNON_02983 1.48e-27 - - - - - - - -
NHGFBNON_02984 6.02e-135 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NHGFBNON_02985 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NHGFBNON_02986 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NHGFBNON_02987 1.01e-188 - - - - - - - -
NHGFBNON_02988 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
NHGFBNON_02989 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHGFBNON_02990 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGFBNON_02991 1.28e-54 - - - - - - - -
NHGFBNON_02993 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHGFBNON_02994 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NHGFBNON_02995 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_02996 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NHGFBNON_02997 2.99e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NHGFBNON_02998 1.34e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NHGFBNON_02999 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NHGFBNON_03000 9.06e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
NHGFBNON_03001 9.38e-317 steT - - E ko:K03294 - ko00000 amino acid
NHGFBNON_03002 2.98e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHGFBNON_03003 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
NHGFBNON_03004 3.08e-93 - - - K - - - MarR family
NHGFBNON_03005 9.23e-269 - - - EGP - - - Major Facilitator Superfamily
NHGFBNON_03006 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
NHGFBNON_03007 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
NHGFBNON_03008 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHGFBNON_03009 4.6e-102 rppH3 - - F - - - NUDIX domain
NHGFBNON_03010 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
NHGFBNON_03011 1.61e-36 - - - - - - - -
NHGFBNON_03012 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
NHGFBNON_03013 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
NHGFBNON_03014 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NHGFBNON_03015 1.39e-225 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NHGFBNON_03016 6.4e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NHGFBNON_03017 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NHGFBNON_03018 1.46e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NHGFBNON_03019 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NHGFBNON_03020 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NHGFBNON_03021 1.08e-71 - - - - - - - -
NHGFBNON_03022 5.57e-83 - - - K - - - Helix-turn-helix domain
NHGFBNON_03023 0.0 - - - L - - - AAA domain
NHGFBNON_03024 1.16e-148 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
NHGFBNON_03025 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
NHGFBNON_03026 4.73e-302 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
NHGFBNON_03027 1.14e-292 - - - S - - - Cysteine-rich secretory protein family
NHGFBNON_03028 1.59e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHGFBNON_03029 2.08e-93 - - - D - - - nuclear chromosome segregation
NHGFBNON_03030 2.57e-104 - - - - - - - -
NHGFBNON_03031 9.14e-204 - - - S - - - Domain of unknown function (DUF4767)
NHGFBNON_03032 6.35e-69 - - - - - - - -
NHGFBNON_03033 3.61e-61 - - - S - - - MORN repeat
NHGFBNON_03034 0.0 XK27_09800 - - I - - - Acyltransferase family
NHGFBNON_03035 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
NHGFBNON_03036 1.95e-116 - - - - - - - -
NHGFBNON_03037 5.74e-32 - - - - - - - -
NHGFBNON_03038 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
NHGFBNON_03039 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
NHGFBNON_03040 4.76e-191 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
NHGFBNON_03041 2.11e-211 yjdB - - S - - - Domain of unknown function (DUF4767)
NHGFBNON_03042 4.46e-63 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NHGFBNON_03043 3.1e-131 - - - G - - - Glycogen debranching enzyme
NHGFBNON_03044 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NHGFBNON_03045 2.38e-102 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NHGFBNON_03046 1.44e-33 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
NHGFBNON_03047 9.97e-108 - - - L - - - PFAM Integrase catalytic region
NHGFBNON_03049 2.81e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
NHGFBNON_03050 0.0 - - - M - - - MucBP domain
NHGFBNON_03051 1.13e-62 - - - M - - - MucBP domain
NHGFBNON_03052 1.42e-08 - - - - - - - -
NHGFBNON_03053 1.27e-115 - - - S - - - AAA domain
NHGFBNON_03054 7.45e-180 - - - K - - - sequence-specific DNA binding
NHGFBNON_03055 1.09e-123 - - - K - - - Helix-turn-helix domain
NHGFBNON_03056 1.6e-219 - - - K - - - Transcriptional regulator
NHGFBNON_03057 0.0 - - - C - - - FMN_bind
NHGFBNON_03059 3.54e-105 - - - K - - - Transcriptional regulator
NHGFBNON_03060 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHGFBNON_03061 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NHGFBNON_03062 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NHGFBNON_03063 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NHGFBNON_03064 7.64e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHGFBNON_03065 1.56e-55 - - - - - - - -
NHGFBNON_03066 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
NHGFBNON_03067 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NHGFBNON_03068 1.65e-209 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHGFBNON_03069 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHGFBNON_03070 1.44e-179 - - - S - - - NADPH-dependent FMN reductase
NHGFBNON_03071 3.91e-244 - - - - - - - -
NHGFBNON_03072 3.42e-280 yibE - - S - - - overlaps another CDS with the same product name
NHGFBNON_03073 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
NHGFBNON_03074 3.36e-132 - - - K - - - FR47-like protein
NHGFBNON_03075 1.19e-153 gpm5 - - G - - - Phosphoglycerate mutase family
NHGFBNON_03076 3.33e-64 - - - - - - - -
NHGFBNON_03077 6.73e-243 - - - I - - - alpha/beta hydrolase fold
NHGFBNON_03078 0.0 xylP2 - - G - - - symporter
NHGFBNON_03079 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHGFBNON_03080 1.99e-280 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NHGFBNON_03081 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NHGFBNON_03082 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NHGFBNON_03083 1.43e-155 azlC - - E - - - branched-chain amino acid
NHGFBNON_03084 1.75e-47 - - - K - - - MerR HTH family regulatory protein
NHGFBNON_03085 9.04e-179 - - - - - - - -
NHGFBNON_03086 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
NHGFBNON_03087 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NHGFBNON_03088 7.79e-112 - - - K - - - MerR HTH family regulatory protein
NHGFBNON_03089 1.36e-77 - - - - - - - -
NHGFBNON_03090 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NHGFBNON_03091 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NHGFBNON_03092 4.6e-169 - - - S - - - Putative threonine/serine exporter
NHGFBNON_03093 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)