Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IIGIHDMM_00002	8.23e-39	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
IIGIHDMM_00014	2.03e-39	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
IIGIHDMM_00015	4.67e-146	-	-	-	S	-	-	-	(CBS) domain
IIGIHDMM_00016	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIGIHDMM_00017	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIGIHDMM_00018	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
IIGIHDMM_00019	1.44e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IIGIHDMM_00020	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
IIGIHDMM_00021	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIGIHDMM_00022	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IIGIHDMM_00023	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIGIHDMM_00024	4.59e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIGIHDMM_00025	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIGIHDMM_00026	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IIGIHDMM_00027	3.12e-111	-	-	-	-	-	-	-	-
IIGIHDMM_00029	2.71e-87	-	-	-	K	-	-	-	Bacterial transcriptional regulator
IIGIHDMM_00030	6.96e-207	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
IIGIHDMM_00031	1.44e-109	-	-	-	C	-	-	-	Flavodoxin
IIGIHDMM_00032	1.76e-105	-	-	-	S	-	-	-	Cupin domain
IIGIHDMM_00033	6.68e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
IIGIHDMM_00034	1.95e-307	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IIGIHDMM_00035	9.74e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IIGIHDMM_00036	9.18e-317	yhdP	-	-	S	-	-	-	Transporter associated domain
IIGIHDMM_00037	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
IIGIHDMM_00038	8.63e-185	-	-	-	S	-	-	-	DUF218 domain
IIGIHDMM_00039	1.96e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIGIHDMM_00040	2.52e-76	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIGIHDMM_00041	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIGIHDMM_00042	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
IIGIHDMM_00043	9.71e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
IIGIHDMM_00044	1.05e-290	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IIGIHDMM_00045	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IIGIHDMM_00047	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IIGIHDMM_00048	3.44e-202	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IIGIHDMM_00049	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIGIHDMM_00050	7.11e-57	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
IIGIHDMM_00051	3.91e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
IIGIHDMM_00052	1.98e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IIGIHDMM_00053	4.72e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGIHDMM_00054	1.98e-26	-	-	-	-	-	-	-	-
IIGIHDMM_00055	2.29e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
IIGIHDMM_00056	4.8e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IIGIHDMM_00057	3.92e-64	yrvD	-	-	S	-	-	-	Pfam:DUF1049
IIGIHDMM_00062	3.52e-40	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
IIGIHDMM_00065	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_00066	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_00067	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IIGIHDMM_00068	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_00069	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_00072	7.21e-268	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IIGIHDMM_00073	2.08e-154	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IIGIHDMM_00074	5.34e-22	-	-	-	-	-	-	-	-
IIGIHDMM_00075	3.7e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
IIGIHDMM_00076	1.54e-116	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
IIGIHDMM_00077	9.8e-75	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IIGIHDMM_00078	5.8e-247	flp	-	-	V	-	-	-	Beta-lactamase
IIGIHDMM_00079	2.6e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IIGIHDMM_00080	4.15e-160	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
IIGIHDMM_00081	4.57e-140	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
IIGIHDMM_00083	7.21e-157	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IIGIHDMM_00084	2.24e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
IIGIHDMM_00085	3.11e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
IIGIHDMM_00086	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
IIGIHDMM_00087	0.0	-	-	-	S	-	-	-	amidohydrolase
IIGIHDMM_00088	7.02e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGIHDMM_00089	1.7e-186	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIGIHDMM_00091	1.65e-206	-	-	-	S	-	-	-	reductase
IIGIHDMM_00092	1.53e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
IIGIHDMM_00093	4.93e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IIGIHDMM_00094	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IIGIHDMM_00095	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIGIHDMM_00096	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IIGIHDMM_00097	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIGIHDMM_00098	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIGIHDMM_00099	3.77e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
IIGIHDMM_00100	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIGIHDMM_00101	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIGIHDMM_00102	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IIGIHDMM_00103	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIGIHDMM_00104	4.91e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIGIHDMM_00105	1.73e-160	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
IIGIHDMM_00106	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IIGIHDMM_00107	8.44e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIGIHDMM_00108	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIGIHDMM_00109	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIGIHDMM_00110	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IIGIHDMM_00111	4.18e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIGIHDMM_00112	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIGIHDMM_00113	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IIGIHDMM_00114	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IIGIHDMM_00115	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IIGIHDMM_00116	5.11e-267	yttB	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_00117	1.5e-78	-	-	-	-	-	-	-	-
IIGIHDMM_00118	2.17e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
IIGIHDMM_00119	2.02e-97	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IIGIHDMM_00121	1.88e-96	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
IIGIHDMM_00122	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IIGIHDMM_00124	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IIGIHDMM_00125	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIGIHDMM_00126	0.0	yycH	-	-	S	-	-	-	YycH protein
IIGIHDMM_00127	6.12e-194	yycI	-	-	S	-	-	-	YycH protein
IIGIHDMM_00128	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IIGIHDMM_00129	2.87e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IIGIHDMM_00130	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
IIGIHDMM_00131	6.32e-227	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IIGIHDMM_00132	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIGIHDMM_00134	1.83e-124	-	-	-	S	-	-	-	reductase
IIGIHDMM_00135	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
IIGIHDMM_00136	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IIGIHDMM_00137	1.46e-190	-	-	-	E	-	-	-	Glyoxalase-like domain
IIGIHDMM_00138	2.91e-187	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIGIHDMM_00139	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IIGIHDMM_00140	4.09e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIGIHDMM_00141	3.99e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IIGIHDMM_00142	7.92e-272	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
IIGIHDMM_00143	5.95e-64	-	-	-	-	-	-	-	-
IIGIHDMM_00144	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IIGIHDMM_00146	1.4e-68	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
IIGIHDMM_00147	1.08e-112	-	-	-	K	-	-	-	FR47-like protein
IIGIHDMM_00148	2.21e-156	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
IIGIHDMM_00150	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
IIGIHDMM_00151	2.1e-222	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGIHDMM_00152	5.24e-278	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIGIHDMM_00153	8.68e-44	-	-	-	-	-	-	-	-
IIGIHDMM_00154	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
IIGIHDMM_00155	5.52e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IIGIHDMM_00156	9.73e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
IIGIHDMM_00157	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_00158	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_00159	4.13e-116	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
IIGIHDMM_00160	6.93e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IIGIHDMM_00161	3.77e-246	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
IIGIHDMM_00162	8.04e-168	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
IIGIHDMM_00163	3.23e-145	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IIGIHDMM_00164	4.6e-171	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IIGIHDMM_00165	5.97e-132	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
IIGIHDMM_00166	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
IIGIHDMM_00167	1.56e-229	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
IIGIHDMM_00168	4.18e-209	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IIGIHDMM_00169	3.96e-293	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IIGIHDMM_00170	2.72e-102	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
IIGIHDMM_00171	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
IIGIHDMM_00172	2.92e-190	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
IIGIHDMM_00173	2.04e-151	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IIGIHDMM_00174	7.35e-70	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IIGIHDMM_00175	3.65e-170	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IIGIHDMM_00176	8.58e-159	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGIHDMM_00177	2.5e-187	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
IIGIHDMM_00178	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGIHDMM_00179	3.65e-172	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
IIGIHDMM_00180	2.13e-170	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGIHDMM_00181	6.46e-243	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
IIGIHDMM_00182	5.84e-174	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGIHDMM_00183	2.28e-121	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IIGIHDMM_00184	5.13e-144	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
IIGIHDMM_00185	5.79e-269	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IIGIHDMM_00186	1.39e-159	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
IIGIHDMM_00187	6.6e-229	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IIGIHDMM_00188	0.0	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
IIGIHDMM_00189	4.03e-263	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
IIGIHDMM_00190	1.13e-132	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
IIGIHDMM_00191	6.94e-200	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
IIGIHDMM_00192	1.47e-100	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IIGIHDMM_00193	2.69e-95	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
IIGIHDMM_00194	1.64e-110	-	-	-	P	-	-	-	Cadmium resistance transporter
IIGIHDMM_00195	1.11e-154	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IIGIHDMM_00196	1.34e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
IIGIHDMM_00197	3.32e-74	-	-	-	E	ko:K04031	-	ko00000	BMC
IIGIHDMM_00198	1.3e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIGIHDMM_00199	6.52e-270	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
IIGIHDMM_00200	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
IIGIHDMM_00201	1.01e-104	pduO	-	-	S	-	-	-	Haem-degrading
IIGIHDMM_00202	1.79e-137	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
IIGIHDMM_00203	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
IIGIHDMM_00204	2.75e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
IIGIHDMM_00205	1.77e-151	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
IIGIHDMM_00206	1.18e-56	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
IIGIHDMM_00207	3.28e-112	-	-	-	CQ	-	-	-	BMC
IIGIHDMM_00208	8.32e-79	pduH	-	-	S	-	-	-	Dehydratase medium subunit
IIGIHDMM_00209	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
IIGIHDMM_00210	1.1e-106	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
IIGIHDMM_00211	5.43e-166	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
IIGIHDMM_00212	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
IIGIHDMM_00213	4.84e-170	pduB	-	-	E	-	-	-	BMC
IIGIHDMM_00214	2.72e-56	-	-	-	CQ	-	-	-	BMC
IIGIHDMM_00215	9.39e-256	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGIHDMM_00216	4.46e-190	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
IIGIHDMM_00217	4.17e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IIGIHDMM_00218	7.23e-209	-	-	-	-	-	-	-	-
IIGIHDMM_00219	2.24e-201	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
IIGIHDMM_00220	6.83e-239	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
IIGIHDMM_00221	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
IIGIHDMM_00222	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00223	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IIGIHDMM_00224	8.08e-117	-	-	-	GM	-	-	-	epimerase
IIGIHDMM_00225	1.7e-199	-	-	-	V	-	-	-	(ABC) transporter
IIGIHDMM_00226	1.23e-309	yhdP	-	-	S	-	-	-	Transporter associated domain
IIGIHDMM_00227	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IIGIHDMM_00228	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
IIGIHDMM_00229	1.52e-245	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
IIGIHDMM_00230	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IIGIHDMM_00231	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIGIHDMM_00232	1.29e-54	-	-	-	-	-	-	-	-
IIGIHDMM_00233	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IIGIHDMM_00234	5.76e-08	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IIGIHDMM_00235	6.65e-104	usp5	-	-	T	-	-	-	universal stress protein
IIGIHDMM_00236	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
IIGIHDMM_00237	2.14e-296	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIGIHDMM_00238	3.11e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
IIGIHDMM_00239	6.88e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IIGIHDMM_00240	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IIGIHDMM_00241	1.72e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIGIHDMM_00242	1.83e-232	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
IIGIHDMM_00243	1.63e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IIGIHDMM_00244	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IIGIHDMM_00245	1.21e-48	-	-	-	-	-	-	-	-
IIGIHDMM_00246	1.24e-68	-	-	-	-	-	-	-	-
IIGIHDMM_00247	3.71e-260	-	-	-	-	-	-	-	-
IIGIHDMM_00248	3.89e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIGIHDMM_00249	5.87e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIGIHDMM_00250	6.94e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
IIGIHDMM_00251	2.15e-161	XK27_10500	-	-	K	-	-	-	response regulator
IIGIHDMM_00252	7.79e-236	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
IIGIHDMM_00253	1.75e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00254	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IIGIHDMM_00255	8.48e-203	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IIGIHDMM_00256	3.59e-211	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIGIHDMM_00257	1.39e-69	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IIGIHDMM_00258	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIGIHDMM_00259	2.45e-251	-	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_00260	1.87e-116	ymdB	-	-	S	-	-	-	Macro domain protein
IIGIHDMM_00261	1.02e-135	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGIHDMM_00262	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IIGIHDMM_00263	2.1e-64	-	-	-	-	-	-	-	-
IIGIHDMM_00264	3.87e-300	-	-	-	S	-	-	-	Putative metallopeptidase domain
IIGIHDMM_00265	1.02e-261	-	-	-	S	-	-	-	associated with various cellular activities
IIGIHDMM_00266	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IIGIHDMM_00267	1.92e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IIGIHDMM_00269	5.59e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
IIGIHDMM_00270	3.32e-72	-	-	-	-	-	-	-	-
IIGIHDMM_00272	5.82e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IIGIHDMM_00273	3.53e-66	-	-	-	-	-	-	-	-
IIGIHDMM_00274	5.91e-07	-	-	-	L	-	-	-	Transposase
IIGIHDMM_00275	0.000103	-	-	-	-	-	-	-	-
IIGIHDMM_00277	1.69e-16	-	-	-	K	-	-	-	Helix-turn-helix domain
IIGIHDMM_00279	3.05e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
IIGIHDMM_00280	1.28e-273	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IIGIHDMM_00281	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IIGIHDMM_00282	1.72e-136	-	-	-	NU	-	-	-	mannosyl-glycoprotein
IIGIHDMM_00283	8.38e-186	-	-	-	S	-	-	-	Putative ABC-transporter type IV
IIGIHDMM_00284	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IIGIHDMM_00288	4.75e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
IIGIHDMM_00289	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IIGIHDMM_00290	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIGIHDMM_00291	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00292	1.93e-119	-	-	-	P	-	-	-	Cadmium resistance transporter
IIGIHDMM_00293	2.39e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IIGIHDMM_00294	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_00295	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_00296	2.81e-138	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
IIGIHDMM_00297	7.49e-12	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IIGIHDMM_00299	1.99e-101	-	-	-	K	-	-	-	Putative DNA-binding domain
IIGIHDMM_00300	2.54e-12	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
IIGIHDMM_00303	1.69e-45	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
IIGIHDMM_00304	8.67e-22	-	-	-	-	-	-	-	-
IIGIHDMM_00305	0.0	-	-	-	L	-	-	-	PLD-like domain
IIGIHDMM_00307	5.67e-232	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
IIGIHDMM_00308	1.13e-248	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IIGIHDMM_00309	2.55e-119	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IIGIHDMM_00310	7.24e-284	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IIGIHDMM_00311	1.11e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IIGIHDMM_00312	5.2e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
IIGIHDMM_00313	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IIGIHDMM_00314	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
IIGIHDMM_00315	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
IIGIHDMM_00316	9.18e-83	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
IIGIHDMM_00317	4.03e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IIGIHDMM_00318	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IIGIHDMM_00319	7.12e-198	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IIGIHDMM_00320	4.31e-245	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IIGIHDMM_00321	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
IIGIHDMM_00322	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IIGIHDMM_00323	1.94e-304	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IIGIHDMM_00324	5.25e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIGIHDMM_00325	4.34e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IIGIHDMM_00326	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IIGIHDMM_00327	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IIGIHDMM_00328	8.13e-207	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IIGIHDMM_00329	3.4e-146	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
IIGIHDMM_00330	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
IIGIHDMM_00331	1.11e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
IIGIHDMM_00332	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IIGIHDMM_00333	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
IIGIHDMM_00334	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
IIGIHDMM_00335	9.7e-168	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
IIGIHDMM_00336	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
IIGIHDMM_00337	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
IIGIHDMM_00338	1.19e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIGIHDMM_00339	1.22e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IIGIHDMM_00340	2.72e-238	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
IIGIHDMM_00341	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IIGIHDMM_00342	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
IIGIHDMM_00343	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIGIHDMM_00344	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IIGIHDMM_00345	2.33e-215	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IIGIHDMM_00346	1.72e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IIGIHDMM_00347	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IIGIHDMM_00348	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IIGIHDMM_00349	2.38e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IIGIHDMM_00350	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
IIGIHDMM_00351	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IIGIHDMM_00352	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIGIHDMM_00353	1.05e-133	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IIGIHDMM_00354	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIGIHDMM_00355	4.13e-109	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IIGIHDMM_00356	2.52e-284	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IIGIHDMM_00357	7.37e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
IIGIHDMM_00358	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
IIGIHDMM_00359	3.61e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIGIHDMM_00360	5.85e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIGIHDMM_00361	3.19e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
IIGIHDMM_00362	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IIGIHDMM_00363	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IIGIHDMM_00364	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
IIGIHDMM_00365	1.58e-125	-	-	-	-	-	-	-	-
IIGIHDMM_00366	9.78e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIGIHDMM_00367	1.03e-202	gspA	-	-	M	-	-	-	family 8
IIGIHDMM_00368	4.91e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
IIGIHDMM_00369	9.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGIHDMM_00370	3.82e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IIGIHDMM_00371	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IIGIHDMM_00372	4.08e-216	yvgN	-	-	C	-	-	-	Aldo keto reductase
IIGIHDMM_00373	2.66e-117	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
IIGIHDMM_00374	2.95e-279	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IIGIHDMM_00375	2.08e-284	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IIGIHDMM_00376	2.25e-115	-	-	-	S	-	-	-	module of peptide synthetase
IIGIHDMM_00378	1.49e-184	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IIGIHDMM_00379	9.31e-153	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IIGIHDMM_00380	8.82e-89	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
IIGIHDMM_00381	1.62e-200	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IIGIHDMM_00382	4.04e-155	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
IIGIHDMM_00383	8.67e-67	kdgR	-	-	K	-	-	-	FCD domain
IIGIHDMM_00384	6.59e-262	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
IIGIHDMM_00385	3.9e-229	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IIGIHDMM_00386	6.34e-270	uxuT	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
IIGIHDMM_00387	3.83e-274	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IIGIHDMM_00388	4.08e-170	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IIGIHDMM_00389	2.27e-164	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIGIHDMM_00390	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_00391	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_00392	4.08e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIGIHDMM_00393	7.41e-153	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIGIHDMM_00394	1.15e-262	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IIGIHDMM_00395	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGIHDMM_00396	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
IIGIHDMM_00397	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IIGIHDMM_00398	1.25e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIGIHDMM_00399	1.61e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIGIHDMM_00401	4.59e-248	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IIGIHDMM_00402	3.36e-130	-	-	-	S	-	-	-	glycosyl transferase family 2
IIGIHDMM_00403	6.21e-266	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
IIGIHDMM_00404	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IIGIHDMM_00405	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
IIGIHDMM_00406	8.18e-211	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
IIGIHDMM_00407	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIGIHDMM_00408	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IIGIHDMM_00409	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IIGIHDMM_00411	2.68e-82	-	-	-	M	-	-	-	family 8
IIGIHDMM_00412	3.55e-252	-	-	-	M	-	-	-	family 8
IIGIHDMM_00413	0.0	-	-	-	M	-	-	-	family 8
IIGIHDMM_00415	1.48e-208	-	-	-	L	ko:K07487	-	ko00000	Transposase
IIGIHDMM_00417	1.83e-21	-	-	-	-	-	-	-	-
IIGIHDMM_00418	1.01e-308	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
IIGIHDMM_00419	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIGIHDMM_00421	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIGIHDMM_00422	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IIGIHDMM_00423	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIGIHDMM_00424	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIGIHDMM_00425	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
IIGIHDMM_00426	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIGIHDMM_00427	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IIGIHDMM_00428	4.87e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
IIGIHDMM_00429	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIGIHDMM_00430	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIGIHDMM_00431	1.36e-136	-	-	-	-	-	-	-	-
IIGIHDMM_00432	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIGIHDMM_00433	5.64e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IIGIHDMM_00434	1.71e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IIGIHDMM_00435	8.81e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGIHDMM_00436	7.17e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IIGIHDMM_00437	6.15e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIGIHDMM_00438	6.77e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IIGIHDMM_00439	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIGIHDMM_00440	1.67e-86	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IIGIHDMM_00441	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
IIGIHDMM_00442	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIGIHDMM_00443	1.11e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
IIGIHDMM_00444	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIGIHDMM_00445	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIGIHDMM_00446	5.17e-70	-	-	-	-	-	-	-	-
IIGIHDMM_00447	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IIGIHDMM_00448	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00449	2.22e-190	-	-	-	S	-	-	-	Cof-like hydrolase
IIGIHDMM_00450	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
IIGIHDMM_00452	2.31e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
IIGIHDMM_00453	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IIGIHDMM_00454	1.91e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
IIGIHDMM_00455	8.52e-154	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IIGIHDMM_00456	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IIGIHDMM_00457	2.69e-36	-	-	-	-	-	-	-	-
IIGIHDMM_00458	4.2e-150	-	-	-	L	ko:K07487	-	ko00000	Transposase
IIGIHDMM_00459	2.76e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IIGIHDMM_00460	6.97e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IIGIHDMM_00461	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IIGIHDMM_00462	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IIGIHDMM_00463	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IIGIHDMM_00464	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIGIHDMM_00465	2.12e-19	-	-	-	-	-	-	-	-
IIGIHDMM_00466	1.45e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
IIGIHDMM_00467	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IIGIHDMM_00468	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
IIGIHDMM_00469	2e-206	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
IIGIHDMM_00470	3.01e-274	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIGIHDMM_00471	8.29e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIGIHDMM_00472	1.78e-202	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
IIGIHDMM_00473	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
IIGIHDMM_00474	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
IIGIHDMM_00475	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IIGIHDMM_00476	9.83e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IIGIHDMM_00477	1.03e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIGIHDMM_00478	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIGIHDMM_00479	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
IIGIHDMM_00480	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
IIGIHDMM_00481	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIGIHDMM_00482	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIGIHDMM_00483	1.13e-120	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIGIHDMM_00484	2.01e-146	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IIGIHDMM_00485	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IIGIHDMM_00486	5.25e-142	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IIGIHDMM_00487	3.04e-48	-	-	-	C	-	-	-	Nitroreductase family
IIGIHDMM_00488	5.27e-300	-	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_00489	3.07e-89	-	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00490	4.38e-52	-	-	-	-	-	-	-	-
IIGIHDMM_00491	0.0	ydaO	-	-	E	-	-	-	amino acid
IIGIHDMM_00492	0.0	-	-	-	E	-	-	-	amino acid
IIGIHDMM_00493	2.37e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
IIGIHDMM_00494	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIGIHDMM_00495	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIGIHDMM_00497	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIGIHDMM_00498	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IIGIHDMM_00499	2.51e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIGIHDMM_00500	1.72e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIGIHDMM_00501	5.43e-183	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
IIGIHDMM_00502	3.64e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIGIHDMM_00503	1.04e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIGIHDMM_00504	5.14e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIGIHDMM_00505	3.52e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIGIHDMM_00506	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IIGIHDMM_00507	8.56e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IIGIHDMM_00508	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IIGIHDMM_00509	8.28e-225	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIGIHDMM_00510	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IIGIHDMM_00511	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIGIHDMM_00512	3.67e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IIGIHDMM_00513	1.34e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIGIHDMM_00514	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IIGIHDMM_00515	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIGIHDMM_00516	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IIGIHDMM_00517	5.48e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIGIHDMM_00518	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IIGIHDMM_00519	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIGIHDMM_00520	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIGIHDMM_00521	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIGIHDMM_00522	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIGIHDMM_00523	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IIGIHDMM_00524	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIGIHDMM_00525	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIGIHDMM_00526	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IIGIHDMM_00527	2.19e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IIGIHDMM_00528	5.74e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
IIGIHDMM_00529	4.63e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
IIGIHDMM_00530	1.2e-64	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIGIHDMM_00532	2.39e-64	-	-	-	-	-	-	-	-
IIGIHDMM_00533	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIGIHDMM_00534	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIGIHDMM_00535	2.18e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIGIHDMM_00536	3.97e-313	-	-	-	M	-	-	-	Glycosyl transferase family group 2
IIGIHDMM_00538	6.5e-289	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
IIGIHDMM_00539	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIGIHDMM_00540	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIGIHDMM_00541	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IIGIHDMM_00542	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IIGIHDMM_00543	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IIGIHDMM_00544	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIGIHDMM_00545	2.16e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIGIHDMM_00546	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIGIHDMM_00547	5.12e-266	yacL	-	-	S	-	-	-	domain protein
IIGIHDMM_00548	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIGIHDMM_00549	4.86e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IIGIHDMM_00550	2.84e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IIGIHDMM_00551	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIGIHDMM_00552	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IIGIHDMM_00553	8.63e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIGIHDMM_00554	1.43e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00555	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGIHDMM_00556	9e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IIGIHDMM_00557	5.16e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIGIHDMM_00558	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIGIHDMM_00559	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IIGIHDMM_00560	5.27e-235	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
IIGIHDMM_00561	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IIGIHDMM_00563	3.33e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IIGIHDMM_00564	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
IIGIHDMM_00565	6.15e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIGIHDMM_00566	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIGIHDMM_00567	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IIGIHDMM_00568	4.65e-167	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IIGIHDMM_00569	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
IIGIHDMM_00570	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_00571	7.43e-144	-	-	-	-	-	-	-	-
IIGIHDMM_00574	2.49e-191	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIGIHDMM_00575	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
IIGIHDMM_00580	5.79e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IIGIHDMM_00581	4.72e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
IIGIHDMM_00582	2.17e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIGIHDMM_00583	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IIGIHDMM_00584	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IIGIHDMM_00585	4.86e-77	-	-	-	-	-	-	-	-
IIGIHDMM_00586	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IIGIHDMM_00587	2.56e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIGIHDMM_00588	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IIGIHDMM_00589	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IIGIHDMM_00590	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIGIHDMM_00591	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIGIHDMM_00592	4.86e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIGIHDMM_00593	4.49e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIGIHDMM_00594	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIGIHDMM_00595	1.87e-288	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIGIHDMM_00596	1.57e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIGIHDMM_00597	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IIGIHDMM_00598	3.05e-189	ylmH	-	-	S	-	-	-	S4 domain protein
IIGIHDMM_00599	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
IIGIHDMM_00600	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIGIHDMM_00601	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IIGIHDMM_00602	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IIGIHDMM_00603	7.05e-23	-	-	-	-	-	-	-	-
IIGIHDMM_00604	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIGIHDMM_00605	1.28e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IIGIHDMM_00606	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IIGIHDMM_00607	1.86e-277	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIGIHDMM_00608	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
IIGIHDMM_00609	3.82e-157	-	-	-	S	-	-	-	repeat protein
IIGIHDMM_00610	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIGIHDMM_00611	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIGIHDMM_00612	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_00613	5.94e-249	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_00614	7.15e-216	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IIGIHDMM_00615	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IIGIHDMM_00616	7.15e-315	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIGIHDMM_00617	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIGIHDMM_00618	1.91e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIGIHDMM_00619	3.25e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIGIHDMM_00620	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIGIHDMM_00621	2.06e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIGIHDMM_00622	1.82e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIGIHDMM_00623	3.29e-103	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
IIGIHDMM_00624	3.29e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
IIGIHDMM_00625	3.58e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IIGIHDMM_00626	2.15e-75	-	-	-	-	-	-	-	-
IIGIHDMM_00628	8.52e-232	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IIGIHDMM_00629	4.37e-39	-	-	-	-	-	-	-	-
IIGIHDMM_00630	2.71e-235	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
IIGIHDMM_00631	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IIGIHDMM_00632	3.97e-107	-	-	-	-	-	-	-	-
IIGIHDMM_00633	1.68e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIGIHDMM_00634	4.05e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IIGIHDMM_00635	4.67e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
IIGIHDMM_00636	1.23e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIGIHDMM_00637	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IIGIHDMM_00638	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IIGIHDMM_00639	1.01e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IIGIHDMM_00640	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IIGIHDMM_00641	1.3e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IIGIHDMM_00642	9.06e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
IIGIHDMM_00643	1.95e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IIGIHDMM_00644	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIGIHDMM_00645	1.49e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IIGIHDMM_00646	1.44e-139	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IIGIHDMM_00647	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IIGIHDMM_00648	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IIGIHDMM_00649	2.67e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IIGIHDMM_00650	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IIGIHDMM_00651	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIGIHDMM_00652	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIGIHDMM_00653	2.07e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
IIGIHDMM_00654	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIGIHDMM_00655	3.2e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIGIHDMM_00656	5.06e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIGIHDMM_00657	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IIGIHDMM_00658	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
IIGIHDMM_00659	2.44e-20	-	-	-	-	-	-	-	-
IIGIHDMM_00660	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIGIHDMM_00661	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIGIHDMM_00662	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIGIHDMM_00663	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGIHDMM_00664	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IIGIHDMM_00665	5.09e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIGIHDMM_00666	1.53e-122	-	-	-	-	-	-	-	-
IIGIHDMM_00667	1.51e-170	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIGIHDMM_00668	1.15e-14	ansR	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00669	6.17e-20	-	-	-	-	-	-	-	-
IIGIHDMM_00670	1.3e-52	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
IIGIHDMM_00671	1.53e-06	-	-	-	S	-	-	-	Helix-turn-helix domain
IIGIHDMM_00677	1.05e-12	-	-	-	L	-	-	-	DnaD domain protein
IIGIHDMM_00679	7.32e-91	-	-	-	-	-	-	-	-
IIGIHDMM_00681	5.89e-200	-	-	-	D	-	-	-	domain protein
IIGIHDMM_00682	9.4e-261	-	-	-	D	-	-	-	domain protein
IIGIHDMM_00684	4.42e-75	-	-	-	-	-	-	-	-
IIGIHDMM_00686	4.17e-163	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIGIHDMM_00687	1.66e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IIGIHDMM_00688	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IIGIHDMM_00689	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
IIGIHDMM_00690	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IIGIHDMM_00691	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IIGIHDMM_00692	1.9e-178	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IIGIHDMM_00693	3.94e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
IIGIHDMM_00694	3.56e-234	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGIHDMM_00695	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IIGIHDMM_00696	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIGIHDMM_00697	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IIGIHDMM_00698	8.54e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIGIHDMM_00699	3.16e-183	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIGIHDMM_00700	5.83e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IIGIHDMM_00701	5.7e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IIGIHDMM_00702	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIGIHDMM_00703	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIGIHDMM_00704	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IIGIHDMM_00705	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IIGIHDMM_00706	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IIGIHDMM_00707	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
IIGIHDMM_00708	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIGIHDMM_00709	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIGIHDMM_00710	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIGIHDMM_00711	8.61e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IIGIHDMM_00712	1.26e-84	-	-	-	-	-	-	-	-
IIGIHDMM_00713	2.77e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIGIHDMM_00714	4.68e-117	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIGIHDMM_00715	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IIGIHDMM_00716	4.44e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIGIHDMM_00717	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIGIHDMM_00718	7.71e-87	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIGIHDMM_00720	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_00721	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_00722	5.52e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IIGIHDMM_00723	9.73e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
IIGIHDMM_00725	1.94e-136	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
IIGIHDMM_00726	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIGIHDMM_00727	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IIGIHDMM_00728	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IIGIHDMM_00729	7.67e-224	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGIHDMM_00730	5.54e-267	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IIGIHDMM_00731	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIGIHDMM_00732	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
IIGIHDMM_00733	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
IIGIHDMM_00734	4.02e-90	-	-	-	-	-	-	-	-
IIGIHDMM_00735	2.5e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IIGIHDMM_00736	8.32e-149	dltr	-	-	K	-	-	-	response regulator
IIGIHDMM_00737	1.41e-283	sptS	-	-	T	-	-	-	Histidine kinase
IIGIHDMM_00738	1.29e-261	-	-	-	P	-	-	-	Voltage gated chloride channel
IIGIHDMM_00739	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIGIHDMM_00740	3.04e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IIGIHDMM_00741	1.48e-214	-	-	-	C	-	-	-	Aldo keto reductase
IIGIHDMM_00742	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
IIGIHDMM_00743	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IIGIHDMM_00744	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IIGIHDMM_00745	1.2e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIGIHDMM_00746	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIGIHDMM_00747	4e-125	-	-	-	-	-	-	-	-
IIGIHDMM_00748	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIGIHDMM_00750	1.45e-145	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
IIGIHDMM_00751	1.94e-91	-	-	-	-	-	-	-	-
IIGIHDMM_00752	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IIGIHDMM_00753	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
IIGIHDMM_00754	0.0	-	-	-	M	-	-	-	domain protein
IIGIHDMM_00755	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
IIGIHDMM_00756	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIGIHDMM_00757	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IIGIHDMM_00758	3.45e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IIGIHDMM_00759	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
IIGIHDMM_00760	6.62e-233	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGIHDMM_00761	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIGIHDMM_00763	1.87e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
IIGIHDMM_00764	8.76e-267	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
IIGIHDMM_00765	1.97e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIGIHDMM_00766	9.73e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
IIGIHDMM_00767	5.52e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
IIGIHDMM_00768	1.05e-153	-	-	-	H	-	-	-	RibD C-terminal domain
IIGIHDMM_00769	2.48e-203	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IIGIHDMM_00770	7.54e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IIGIHDMM_00771	3.99e-144	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
IIGIHDMM_00772	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
IIGIHDMM_00773	1.31e-209	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
IIGIHDMM_00774	1.13e-112	-	-	-	C	-	-	-	Flavodoxin
IIGIHDMM_00775	1.58e-28	-	-	-	-	-	-	-	-
IIGIHDMM_00776	1.81e-191	lysR	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00777	2.48e-112	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
IIGIHDMM_00778	3.79e-171	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
IIGIHDMM_00779	2.79e-193	-	-	-	S	-	-	-	Alpha beta hydrolase
IIGIHDMM_00780	7.79e-216	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
IIGIHDMM_00781	1.5e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IIGIHDMM_00782	3.7e-123	-	-	-	K	-	-	-	Virulence activator alpha C-term
IIGIHDMM_00783	7.98e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGIHDMM_00784	1.19e-213	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IIGIHDMM_00785	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
IIGIHDMM_00786	1.61e-178	-	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00787	5.96e-207	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
IIGIHDMM_00788	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IIGIHDMM_00789	7.63e-252	-	-	-	S	-	-	-	membrane
IIGIHDMM_00790	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGIHDMM_00791	1.74e-85	-	-	-	-	-	-	-	-
IIGIHDMM_00792	8.11e-166	-	-	-	F	-	-	-	glutamine amidotransferase
IIGIHDMM_00793	1.26e-183	-	-	-	T	-	-	-	EAL domain
IIGIHDMM_00794	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
IIGIHDMM_00795	1.72e-109	-	-	-	-	-	-	-	-
IIGIHDMM_00796	7.29e-256	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
IIGIHDMM_00797	1.77e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IIGIHDMM_00798	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IIGIHDMM_00799	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IIGIHDMM_00800	6.51e-122	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IIGIHDMM_00801	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IIGIHDMM_00802	5.05e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
IIGIHDMM_00803	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IIGIHDMM_00804	1.32e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIGIHDMM_00805	1.57e-298	-	-	-	-	-	-	-	-
IIGIHDMM_00806	1.85e-108	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGIHDMM_00807	2.34e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
IIGIHDMM_00808	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGIHDMM_00809	1.29e-155	-	-	-	GM	-	-	-	NmrA-like family
IIGIHDMM_00810	1.27e-99	-	-	-	S	ko:K02348	-	ko00000	Gnat family
IIGIHDMM_00811	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
IIGIHDMM_00812	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
IIGIHDMM_00813	2.23e-54	-	-	-	S	-	-	-	Cytochrome B5
IIGIHDMM_00814	4.09e-271	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IIGIHDMM_00816	5.69e-234	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIGIHDMM_00817	6.35e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
IIGIHDMM_00818	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
IIGIHDMM_00819	1.81e-290	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
IIGIHDMM_00821	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIGIHDMM_00822	4.66e-81	-	-	-	-	-	-	-	-
IIGIHDMM_00823	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIGIHDMM_00824	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
IIGIHDMM_00825	5.3e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
IIGIHDMM_00826	1.76e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGIHDMM_00827	2.03e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00828	1.07e-218	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00829	7.53e-205	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00830	3.38e-50	-	-	-	-	-	-	-	-
IIGIHDMM_00831	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
IIGIHDMM_00832	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIGIHDMM_00833	4.41e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGIHDMM_00834	2.6e-33	-	-	-	-	-	-	-	-
IIGIHDMM_00835	2.83e-144	-	-	-	-	-	-	-	-
IIGIHDMM_00836	1.74e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_00837	1.08e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IIGIHDMM_00838	1.48e-114	-	-	-	-	-	-	-	-
IIGIHDMM_00839	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IIGIHDMM_00840	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IIGIHDMM_00841	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IIGIHDMM_00843	9.2e-130	-	-	-	-	-	-	-	-
IIGIHDMM_00844	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIGIHDMM_00845	3.54e-181	-	-	-	S	-	-	-	Alpha beta hydrolase
IIGIHDMM_00846	1.41e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
IIGIHDMM_00847	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIGIHDMM_00848	1.77e-56	-	-	-	-	-	-	-	-
IIGIHDMM_00849	6.69e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
IIGIHDMM_00850	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IIGIHDMM_00851	8.86e-317	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IIGIHDMM_00852	1.95e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IIGIHDMM_00853	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGIHDMM_00854	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IIGIHDMM_00855	1.41e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IIGIHDMM_00856	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
IIGIHDMM_00857	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIGIHDMM_00858	1.03e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
IIGIHDMM_00859	1.12e-94	-	-	-	M	-	-	-	domain protein
IIGIHDMM_00860	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
IIGIHDMM_00861	6.02e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
IIGIHDMM_00862	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
IIGIHDMM_00863	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IIGIHDMM_00864	6.26e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIGIHDMM_00865	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIGIHDMM_00866	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IIGIHDMM_00867	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIGIHDMM_00868	5.47e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IIGIHDMM_00869	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIGIHDMM_00870	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIGIHDMM_00871	3.55e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IIGIHDMM_00872	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
IIGIHDMM_00873	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIGIHDMM_00874	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIGIHDMM_00875	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IIGIHDMM_00876	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IIGIHDMM_00877	4.69e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIGIHDMM_00878	9.09e-156	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IIGIHDMM_00879	7.88e-210	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IIGIHDMM_00880	4.99e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIGIHDMM_00881	8.03e-194	-	-	-	G	-	-	-	Right handed beta helix region
IIGIHDMM_00882	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IIGIHDMM_00883	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IIGIHDMM_00884	6.49e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIGIHDMM_00885	5.76e-302	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIGIHDMM_00886	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IIGIHDMM_00887	9.55e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIGIHDMM_00888	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIGIHDMM_00889	2.68e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIGIHDMM_00890	1.37e-90	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IIGIHDMM_00891	1.4e-196	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
IIGIHDMM_00892	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
IIGIHDMM_00893	3.27e-190	yidA	-	-	S	-	-	-	hydrolase
IIGIHDMM_00894	1.67e-258	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IIGIHDMM_00895	1.96e-101	-	-	-	-	-	-	-	-
IIGIHDMM_00896	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIGIHDMM_00897	2.74e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIGIHDMM_00898	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IIGIHDMM_00899	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
IIGIHDMM_00900	9.8e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IIGIHDMM_00901	7.87e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IIGIHDMM_00902	2e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IIGIHDMM_00903	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IIGIHDMM_00904	6.92e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIGIHDMM_00905	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIGIHDMM_00906	1.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IIGIHDMM_00907	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIGIHDMM_00908	1.59e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
IIGIHDMM_00910	2.4e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IIGIHDMM_00911	7.71e-228	-	-	-	-	-	-	-	-
IIGIHDMM_00912	2.76e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IIGIHDMM_00913	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IIGIHDMM_00914	1.59e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIGIHDMM_00915	3.71e-235	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
IIGIHDMM_00916	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
IIGIHDMM_00917	0.0	-	-	-	L	-	-	-	DNA helicase
IIGIHDMM_00918	1.1e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIGIHDMM_00920	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIGIHDMM_00921	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
IIGIHDMM_00922	4.89e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIGIHDMM_00923	1.07e-57	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
IIGIHDMM_00924	1.15e-278	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
IIGIHDMM_00925	1.47e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IIGIHDMM_00926	3.24e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IIGIHDMM_00927	1.97e-198	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
IIGIHDMM_00928	2.59e-152	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGIHDMM_00929	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIGIHDMM_00930	1.47e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIGIHDMM_00931	7.14e-138	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGIHDMM_00932	2.49e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
IIGIHDMM_00933	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IIGIHDMM_00934	9.01e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IIGIHDMM_00935	1.73e-132	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
IIGIHDMM_00936	1.01e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_00937	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGIHDMM_00938	1.15e-203	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
IIGIHDMM_00939	2.33e-98	ywnA	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_00940	4.02e-201	-	-	-	GM	-	-	-	NAD(P)H-binding
IIGIHDMM_00941	4.44e-11	-	-	-	-	-	-	-	-
IIGIHDMM_00942	2.28e-270	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
IIGIHDMM_00943	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IIGIHDMM_00944	1.6e-162	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IIGIHDMM_00945	2.21e-164	-	-	-	-	-	-	-	-
IIGIHDMM_00946	2.73e-71	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
IIGIHDMM_00947	1.18e-307	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IIGIHDMM_00949	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IIGIHDMM_00950	2.43e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
IIGIHDMM_00951	1.49e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
IIGIHDMM_00952	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
IIGIHDMM_00953	1.53e-110	-	-	-	S	-	-	-	Membrane
IIGIHDMM_00954	9.23e-185	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IIGIHDMM_00956	4.13e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIGIHDMM_00957	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
IIGIHDMM_00958	2.4e-130	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IIGIHDMM_00960	6.87e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIGIHDMM_00961	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IIGIHDMM_00962	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
IIGIHDMM_00963	1.14e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IIGIHDMM_00964	2.73e-50	-	-	-	-	-	-	-	-
IIGIHDMM_00965	7.07e-167	-	-	-	IQ	-	-	-	dehydrogenase reductase
IIGIHDMM_00966	1.06e-73	-	-	-	-	-	-	-	-
IIGIHDMM_00967	1.68e-65	-	-	-	L	-	-	-	Transposase
IIGIHDMM_00968	7.72e-49	ytpP	-	-	CO	-	-	-	Thioredoxin
IIGIHDMM_00969	1.12e-51	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIGIHDMM_00971	1.01e-122	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
IIGIHDMM_00972	8.86e-177	trxB	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Glucose inhibited division protein A
IIGIHDMM_00973	2.9e-33	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
IIGIHDMM_00974	6.64e-91	M1-798	-	-	K	-	-	-	Rhodanese Homology Domain
IIGIHDMM_00975	3.46e-57	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
IIGIHDMM_00976	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
IIGIHDMM_00998	5.4e-09	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
IIGIHDMM_00999	1.84e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
IIGIHDMM_01000	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIGIHDMM_01001	7.95e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
IIGIHDMM_01002	1.84e-205	-	-	-	EG	-	-	-	EamA-like transporter family
IIGIHDMM_01003	1.8e-132	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IIGIHDMM_01004	1.87e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
IIGIHDMM_01005	1.27e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
IIGIHDMM_01006	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IIGIHDMM_01007	3.98e-116	-	-	-	-	-	-	-	-
IIGIHDMM_01009	1.28e-75	-	-	-	-	-	-	-	-
IIGIHDMM_01010	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIGIHDMM_01012	8.17e-126	-	-	-	-	-	-	-	-
IIGIHDMM_01013	0.0	-	-	-	M	-	-	-	domain protein
IIGIHDMM_01014	7.99e-78	-	-	-	-	-	-	-	-
IIGIHDMM_01015	1.43e-249	ampC	-	-	V	-	-	-	Beta-lactamase
IIGIHDMM_01016	2.07e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
IIGIHDMM_01017	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIGIHDMM_01018	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IIGIHDMM_01019	1.09e-294	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
IIGIHDMM_01020	6.91e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
IIGIHDMM_01021	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
IIGIHDMM_01022	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IIGIHDMM_01023	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIGIHDMM_01024	2.1e-214	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIGIHDMM_01025	6.56e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIGIHDMM_01026	1.01e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIGIHDMM_01027	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIGIHDMM_01028	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIGIHDMM_01029	3.33e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IIGIHDMM_01030	1.64e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IIGIHDMM_01031	9.76e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IIGIHDMM_01032	4.26e-158	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IIGIHDMM_01033	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIGIHDMM_01034	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IIGIHDMM_01035	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIGIHDMM_01036	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIGIHDMM_01037	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIGIHDMM_01038	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIGIHDMM_01039	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IIGIHDMM_01040	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IIGIHDMM_01041	5.19e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIGIHDMM_01042	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IIGIHDMM_01043	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IIGIHDMM_01044	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IIGIHDMM_01045	4.95e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
IIGIHDMM_01046	2.21e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IIGIHDMM_01047	3.82e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGIHDMM_01048	3.9e-276	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Oligosaccharide H symporter
IIGIHDMM_01049	3.29e-214	abf	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
IIGIHDMM_01050	2.06e-184	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
IIGIHDMM_01051	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIGIHDMM_01052	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
IIGIHDMM_01053	6.65e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IIGIHDMM_01054	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IIGIHDMM_01055	1.32e-136	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
IIGIHDMM_01056	1.2e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
IIGIHDMM_01057	4.36e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
IIGIHDMM_01058	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
IIGIHDMM_01059	3.61e-61	-	-	-	-	-	-	-	-
IIGIHDMM_01060	4.83e-312	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IIGIHDMM_01061	8.27e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IIGIHDMM_01062	9.79e-29	-	-	-	-	-	-	-	-
IIGIHDMM_01063	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
IIGIHDMM_01064	4.16e-180	-	-	-	S	-	-	-	Membrane
IIGIHDMM_01065	8.39e-181	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IIGIHDMM_01066	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IIGIHDMM_01067	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IIGIHDMM_01068	1.59e-301	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IIGIHDMM_01070	4.2e-150	-	-	-	L	ko:K07487	-	ko00000	Transposase
IIGIHDMM_01071	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
IIGIHDMM_01072	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
IIGIHDMM_01073	1.87e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IIGIHDMM_01074	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
IIGIHDMM_01075	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIGIHDMM_01076	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIGIHDMM_01077	4.28e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IIGIHDMM_01078	2.37e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIGIHDMM_01079	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIGIHDMM_01080	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
IIGIHDMM_01081	5.68e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
IIGIHDMM_01082	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IIGIHDMM_01083	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IIGIHDMM_01084	3.66e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IIGIHDMM_01085	4.3e-312	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIGIHDMM_01086	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IIGIHDMM_01087	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IIGIHDMM_01088	7.72e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IIGIHDMM_01089	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
IIGIHDMM_01090	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGIHDMM_01091	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01092	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IIGIHDMM_01093	1.23e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IIGIHDMM_01094	9.62e-317	ymfH	-	-	S	-	-	-	Peptidase M16
IIGIHDMM_01095	5.91e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
IIGIHDMM_01096	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIGIHDMM_01097	2.38e-291	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IIGIHDMM_01098	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIGIHDMM_01099	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IIGIHDMM_01100	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIGIHDMM_01101	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIGIHDMM_01102	1.84e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIGIHDMM_01103	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIGIHDMM_01104	8.77e-242	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIGIHDMM_01105	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IIGIHDMM_01106	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IIGIHDMM_01107	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIGIHDMM_01108	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIGIHDMM_01109	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IIGIHDMM_01110	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIGIHDMM_01111	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IIGIHDMM_01112	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
IIGIHDMM_01113	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIGIHDMM_01114	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIGIHDMM_01115	3.51e-125	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IIGIHDMM_01116	3.66e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IIGIHDMM_01117	6.73e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIGIHDMM_01118	2e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IIGIHDMM_01119	2.1e-99	ykuL	-	-	S	-	-	-	(CBS) domain
IIGIHDMM_01120	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIGIHDMM_01121	3.6e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IIGIHDMM_01122	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIGIHDMM_01123	4.51e-76	-	-	-	-	-	-	-	-
IIGIHDMM_01124	1.65e-267	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IIGIHDMM_01125	2.81e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IIGIHDMM_01126	2.32e-178	-	-	-	-	-	-	-	-
IIGIHDMM_01127	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IIGIHDMM_01128	3.28e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IIGIHDMM_01129	1.57e-235	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IIGIHDMM_01130	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IIGIHDMM_01131	1.74e-101	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
IIGIHDMM_01132	1.96e-55	-	-	-	-	-	-	-	-
IIGIHDMM_01133	4.62e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
IIGIHDMM_01135	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IIGIHDMM_01136	3.07e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIGIHDMM_01137	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIGIHDMM_01138	6.53e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IIGIHDMM_01139	8.22e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIGIHDMM_01140	5.12e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IIGIHDMM_01141	1.51e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IIGIHDMM_01142	4.8e-50	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
IIGIHDMM_01143	2.81e-193	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
IIGIHDMM_01144	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_01145	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_01146	1.26e-216	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
IIGIHDMM_01148	5.72e-157	-	-	-	G	-	-	-	Peptidase family M23
IIGIHDMM_01149	1.11e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIGIHDMM_01150	2.27e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIGIHDMM_01151	8.1e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIGIHDMM_01152	1.56e-191	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIGIHDMM_01153	3.96e-314	-	-	-	G	-	-	-	Peptidase_C39 like family
IIGIHDMM_01154	3.74e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
IIGIHDMM_01155	1.68e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGIHDMM_01156	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIGIHDMM_01157	0.0	-	-	-	M	-	-	-	NlpC/P60 family
IIGIHDMM_01158	0.0	-	-	-	S	-	-	-	Peptidase, M23
IIGIHDMM_01159	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
IIGIHDMM_01160	9.47e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01161	9.18e-145	-	-	-	-	-	-	-	-
IIGIHDMM_01162	9.48e-183	-	-	-	G	-	-	-	MucBP domain
IIGIHDMM_01163	2.22e-130	-	-	-	S	-	-	-	Pfam:DUF3816
IIGIHDMM_01164	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IIGIHDMM_01165	1.38e-37	-	-	-	-	-	-	-	-
IIGIHDMM_01166	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IIGIHDMM_01167	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIGIHDMM_01168	1.54e-291	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIGIHDMM_01169	4.82e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIGIHDMM_01170	6.57e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIGIHDMM_01171	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
IIGIHDMM_01172	1.26e-216	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
IIGIHDMM_01173	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IIGIHDMM_01174	6.72e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIGIHDMM_01175	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01176	4.93e-245	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIGIHDMM_01177	2.58e-95	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIGIHDMM_01178	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IIGIHDMM_01179	2.13e-194	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
IIGIHDMM_01180	2.28e-219	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IIGIHDMM_01181	2.01e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
IIGIHDMM_01182	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IIGIHDMM_01183	4.19e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIGIHDMM_01184	3.69e-183	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIGIHDMM_01185	1.65e-208	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IIGIHDMM_01186	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIGIHDMM_01187	2.99e-216	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IIGIHDMM_01188	5.44e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIGIHDMM_01189	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIGIHDMM_01190	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIGIHDMM_01191	3.42e-111	-	-	-	F	-	-	-	NUDIX domain
IIGIHDMM_01192	2.57e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IIGIHDMM_01193	1.5e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
IIGIHDMM_01194	3.19e-66	-	-	-	-	-	-	-	-
IIGIHDMM_01196	1.87e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IIGIHDMM_01197	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGIHDMM_01198	1.04e-33	-	-	-	-	-	-	-	-
IIGIHDMM_01199	3.66e-121	-	-	-	-	-	-	-	-
IIGIHDMM_01200	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IIGIHDMM_01201	4.81e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
IIGIHDMM_01202	2.31e-296	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
IIGIHDMM_01203	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IIGIHDMM_01204	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGIHDMM_01205	3.8e-63	-	-	-	-	-	-	-	-
IIGIHDMM_01206	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IIGIHDMM_01207	1.26e-60	-	-	-	-	-	-	-	-
IIGIHDMM_01208	2.75e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
IIGIHDMM_01209	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IIGIHDMM_01210	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IIGIHDMM_01211	1.76e-89	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IIGIHDMM_01212	8.34e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIGIHDMM_01213	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_01214	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_01215	1.26e-216	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
IIGIHDMM_01216	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIGIHDMM_01217	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IIGIHDMM_01218	6.05e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IIGIHDMM_01219	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IIGIHDMM_01220	2.15e-83	-	-	-	M	-	-	-	Lysin motif
IIGIHDMM_01221	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IIGIHDMM_01222	1.53e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
IIGIHDMM_01223	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIGIHDMM_01224	1.43e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IIGIHDMM_01225	5.49e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIGIHDMM_01226	4.59e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIGIHDMM_01227	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIGIHDMM_01228	1.72e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IIGIHDMM_01229	7.61e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IIGIHDMM_01230	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IIGIHDMM_01231	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IIGIHDMM_01232	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IIGIHDMM_01234	1.55e-22	-	-	-	-	-	-	-	-
IIGIHDMM_01236	4.38e-165	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IIGIHDMM_01237	8.26e-57	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
IIGIHDMM_01238	1.75e-18	-	-	-	-	-	-	-	-
IIGIHDMM_01239	7.36e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
IIGIHDMM_01240	1.7e-85	-	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
IIGIHDMM_01242	7.99e-38	-	-	-	-	-	-	-	-
IIGIHDMM_01243	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
IIGIHDMM_01244	1.25e-200	-	-	-	S	-	-	-	Phage tail protein
IIGIHDMM_01245	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
IIGIHDMM_01247	1.85e-84	-	-	-	S	-	-	-	Phage tail tube protein
IIGIHDMM_01248	3.04e-28	-	-	-	-	-	-	-	-
IIGIHDMM_01249	1.39e-27	-	-	-	-	-	-	-	-
IIGIHDMM_01250	1.77e-50	-	-	-	S	-	-	-	Phage head-tail joining protein
IIGIHDMM_01251	2.07e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IIGIHDMM_01252	3.03e-165	-	-	-	S	-	-	-	Phage capsid family
IIGIHDMM_01253	2.96e-112	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
IIGIHDMM_01254	6.99e-182	-	-	-	S	-	-	-	portal protein
IIGIHDMM_01255	0.0	-	-	-	S	-	-	-	Phage Terminase
IIGIHDMM_01256	1.99e-104	-	-	-	L	-	-	-	Phage terminase, small subunit
IIGIHDMM_01257	5.86e-68	-	-	-	L	-	-	-	HNH nucleases
IIGIHDMM_01270	3.8e-42	-	-	-	-	-	-	-	-
IIGIHDMM_01272	3.53e-174	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIGIHDMM_01283	7.26e-261	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IIGIHDMM_01284	0.0	-	-	-	-	-	-	-	-
IIGIHDMM_01286	1.33e-99	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
IIGIHDMM_01290	2.04e-108	-	-	-	S	-	-	-	nucleoside kinase activity
IIGIHDMM_01296	3.64e-174	-	-	-	-	-	-	-	-
IIGIHDMM_01302	1.85e-94	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
IIGIHDMM_01303	7.91e-44	-	-	-	-	-	-	-	-
IIGIHDMM_01304	2.55e-118	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
IIGIHDMM_01306	5.26e-185	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
IIGIHDMM_01307	1.24e-167	-	-	-	S	-	-	-	Putative HNHc nuclease
IIGIHDMM_01308	1.06e-70	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIGIHDMM_01315	7.69e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
IIGIHDMM_01317	3.32e-61	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IIGIHDMM_01318	3.21e-99	-	-	-	E	-	-	-	IrrE N-terminal-like domain
IIGIHDMM_01324	7.28e-117	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIGIHDMM_01325	2.24e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IIGIHDMM_01326	2.52e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIGIHDMM_01327	5.87e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IIGIHDMM_01328	1.24e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIGIHDMM_01329	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIGIHDMM_01330	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIGIHDMM_01331	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IIGIHDMM_01332	3.05e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IIGIHDMM_01333	1.24e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IIGIHDMM_01334	1.54e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIGIHDMM_01335	4.26e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IIGIHDMM_01336	8.99e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIGIHDMM_01337	6.39e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IIGIHDMM_01338	2.58e-228	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIGIHDMM_01339	2.08e-120	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IIGIHDMM_01340	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IIGIHDMM_01341	4.19e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIGIHDMM_01342	1.2e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIGIHDMM_01343	9.15e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
IIGIHDMM_01344	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IIGIHDMM_01345	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IIGIHDMM_01346	2.2e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01347	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIGIHDMM_01348	1.08e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
IIGIHDMM_01349	3.64e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIGIHDMM_01350	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIGIHDMM_01351	7.97e-71	-	-	-	-	-	-	-	-
IIGIHDMM_01352	4.98e-167	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIGIHDMM_01353	1.14e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IIGIHDMM_01354	7.92e-76	-	-	-	-	-	-	-	-
IIGIHDMM_01356	1.37e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIGIHDMM_01357	2.49e-255	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
IIGIHDMM_01358	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGIHDMM_01359	1.62e-24	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
IIGIHDMM_01360	3.27e-246	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
IIGIHDMM_01364	1.62e-150	-	-	-	K	-	-	-	Peptidase S24-like
IIGIHDMM_01366	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_01367	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_01368	2.91e-255	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIGIHDMM_01369	1.07e-147	-	-	-	S	-	-	-	Membrane
IIGIHDMM_01370	1.9e-162	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
IIGIHDMM_01371	3.82e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIGIHDMM_01372	2.51e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIGIHDMM_01374	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_01375	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_01376	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_01377	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_01378	9.95e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IIGIHDMM_01379	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIGIHDMM_01380	2.64e-226	-	-	-	-	-	-	-	-
IIGIHDMM_01381	1.96e-67	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIGIHDMM_01382	2.73e-264	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
IIGIHDMM_01383	7.22e-206	-	-	-	K	-	-	-	LysR substrate binding domain
IIGIHDMM_01384	1.54e-182	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IIGIHDMM_01385	1.28e-117	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IIGIHDMM_01386	3.72e-139	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGIHDMM_01387	9.45e-126	-	-	-	K	-	-	-	acetyltransferase
IIGIHDMM_01388	1.51e-234	-	-	-	-	-	-	-	-
IIGIHDMM_01390	9.22e-287	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IIGIHDMM_01391	3.59e-128	-	-	-	S	-	-	-	AmiS/UreI family transporter
IIGIHDMM_01392	8.76e-63	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
IIGIHDMM_01393	1.15e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
IIGIHDMM_01394	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
IIGIHDMM_01395	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IIGIHDMM_01396	2.4e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIGIHDMM_01397	1.4e-145	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IIGIHDMM_01398	1.93e-208	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIGIHDMM_01399	4.04e-56	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIGIHDMM_01400	1.46e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIGIHDMM_01401	2.14e-234	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
IIGIHDMM_01402	9.97e-185	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IIGIHDMM_01403	1.9e-173	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGIHDMM_01404	8.65e-165	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
IIGIHDMM_01405	1.64e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IIGIHDMM_01406	9.65e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IIGIHDMM_01407	2.58e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IIGIHDMM_01408	7.41e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIGIHDMM_01409	3.02e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IIGIHDMM_01410	1.33e-196	-	-	-	-	-	-	-	-
IIGIHDMM_01411	1.01e-309	-	-	-	M	-	-	-	Glycosyl transferase
IIGIHDMM_01412	3.16e-280	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
IIGIHDMM_01413	4.47e-178	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IIGIHDMM_01414	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
IIGIHDMM_01415	2.36e-305	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
IIGIHDMM_01416	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
IIGIHDMM_01417	1.08e-113	-	-	-	Q	-	-	-	Methyltransferase
IIGIHDMM_01423	0.000594	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IIGIHDMM_01424	5.41e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIGIHDMM_01425	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IIGIHDMM_01426	5.58e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIGIHDMM_01427	6.38e-123	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
IIGIHDMM_01428	1.43e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IIGIHDMM_01429	1.29e-174	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIGIHDMM_01430	8.38e-216	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IIGIHDMM_01431	1.5e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
IIGIHDMM_01432	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IIGIHDMM_01433	0.0	arcT	-	-	E	-	-	-	Dipeptidase
IIGIHDMM_01434	6.33e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
IIGIHDMM_01435	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
IIGIHDMM_01436	5.58e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
IIGIHDMM_01437	9.44e-281	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIGIHDMM_01438	7.62e-97	-	-	-	-	-	-	-	-
IIGIHDMM_01439	3.02e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IIGIHDMM_01440	6.92e-31	-	-	-	-	-	-	-	-
IIGIHDMM_01443	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IIGIHDMM_01444	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
IIGIHDMM_01445	4.7e-264	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
IIGIHDMM_01446	1.17e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIGIHDMM_01447	6.11e-199	mleR	-	-	K	-	-	-	LysR family
IIGIHDMM_01448	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
IIGIHDMM_01449	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IIGIHDMM_01450	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IIGIHDMM_01451	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IIGIHDMM_01452	2.94e-204	-	-	-	K	-	-	-	LysR family
IIGIHDMM_01453	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
IIGIHDMM_01454	3.85e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
IIGIHDMM_01455	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_01456	3.73e-239	-	-	-	I	-	-	-	Alpha beta
IIGIHDMM_01457	1.07e-119	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IIGIHDMM_01458	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIGIHDMM_01460	1.31e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIGIHDMM_01461	2.33e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
IIGIHDMM_01462	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
IIGIHDMM_01463	1.08e-97	-	-	-	K	-	-	-	MerR HTH family regulatory protein
IIGIHDMM_01464	7.83e-73	-	-	-	-	-	-	-	-
IIGIHDMM_01465	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIGIHDMM_01466	3.85e-280	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIGIHDMM_01467	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGIHDMM_01468	7.44e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGIHDMM_01469	3.85e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGIHDMM_01470	5.41e-171	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01471	2.79e-107	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IIGIHDMM_01472	5.5e-141	-	-	-	S	-	-	-	VIT family
IIGIHDMM_01473	1.27e-152	-	-	-	S	-	-	-	membrane
IIGIHDMM_01474	4.92e-213	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IIGIHDMM_01475	1.34e-160	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
IIGIHDMM_01476	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
IIGIHDMM_01477	8.53e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
IIGIHDMM_01478	7.14e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IIGIHDMM_01479	6.58e-152	-	-	-	I	-	-	-	phosphatase
IIGIHDMM_01480	8.74e-08	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IIGIHDMM_01481	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
IIGIHDMM_01482	1.29e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IIGIHDMM_01488	2.92e-232	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
IIGIHDMM_01489	5.17e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIGIHDMM_01490	1.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IIGIHDMM_01491	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IIGIHDMM_01492	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IIGIHDMM_01493	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIGIHDMM_01494	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIGIHDMM_01495	4.5e-261	-	-	-	-	-	-	-	-
IIGIHDMM_01496	8.01e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
IIGIHDMM_01497	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIGIHDMM_01498	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIGIHDMM_01499	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIGIHDMM_01500	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IIGIHDMM_01501	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIGIHDMM_01502	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IIGIHDMM_01503	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIGIHDMM_01504	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIGIHDMM_01505	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIGIHDMM_01506	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIGIHDMM_01507	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIGIHDMM_01508	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIGIHDMM_01509	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IIGIHDMM_01510	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIGIHDMM_01511	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIGIHDMM_01512	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIGIHDMM_01513	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIGIHDMM_01514	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIGIHDMM_01515	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIGIHDMM_01516	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIGIHDMM_01517	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIGIHDMM_01518	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IIGIHDMM_01519	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IIGIHDMM_01520	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIGIHDMM_01521	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIGIHDMM_01522	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIGIHDMM_01523	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IIGIHDMM_01524	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIGIHDMM_01525	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIGIHDMM_01526	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIGIHDMM_01527	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IIGIHDMM_01528	1.43e-185	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIGIHDMM_01529	3.54e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIGIHDMM_01530	3.51e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIGIHDMM_01531	2.13e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIGIHDMM_01532	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIGIHDMM_01533	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IIGIHDMM_01534	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
IIGIHDMM_01535	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IIGIHDMM_01536	1.94e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIGIHDMM_01537	4.61e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IIGIHDMM_01538	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IIGIHDMM_01539	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIGIHDMM_01540	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
IIGIHDMM_01541	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIGIHDMM_01542	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIGIHDMM_01543	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIGIHDMM_01544	5.72e-239	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IIGIHDMM_01545	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIGIHDMM_01546	2.43e-277	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
IIGIHDMM_01547	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
IIGIHDMM_01548	1.96e-15	-	-	-	-	-	-	-	-
IIGIHDMM_01551	4.42e-217	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
IIGIHDMM_01552	3.79e-78	-	-	-	H	-	-	-	Riboflavin biosynthesis protein RibD
IIGIHDMM_01553	7.31e-57	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IIGIHDMM_01554	3.14e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IIGIHDMM_01555	2.16e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
IIGIHDMM_01556	2.76e-187	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IIGIHDMM_01557	1.02e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGIHDMM_01558	1.22e-64	-	-	-	-	-	-	-	-
IIGIHDMM_01560	1.28e-115	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IIGIHDMM_01561	1.21e-266	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IIGIHDMM_01562	1.89e-316	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
IIGIHDMM_01563	4.05e-115	XK27_07210	-	-	S	-	-	-	B3 4 domain
IIGIHDMM_01564	7.11e-118	-	-	-	-	-	-	-	-
IIGIHDMM_01565	5.28e-159	pnb	-	-	C	-	-	-	nitroreductase
IIGIHDMM_01566	1.02e-97	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
IIGIHDMM_01567	4.76e-217	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
IIGIHDMM_01568	1.17e-216	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
IIGIHDMM_01569	6.48e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IIGIHDMM_01570	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
IIGIHDMM_01571	3.59e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IIGIHDMM_01572	7.31e-27	-	-	-	-	-	-	-	-
IIGIHDMM_01573	1.31e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IIGIHDMM_01574	1.92e-106	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
IIGIHDMM_01575	3.49e-251	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
IIGIHDMM_01576	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIGIHDMM_01577	2.64e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IIGIHDMM_01578	6.77e-142	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IIGIHDMM_01579	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
IIGIHDMM_01580	3.09e-244	mocA	-	-	S	-	-	-	Oxidoreductase
IIGIHDMM_01581	2.32e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IIGIHDMM_01583	9.51e-263	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIGIHDMM_01584	4.26e-74	-	-	-	-	-	-	-	-
IIGIHDMM_01585	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IIGIHDMM_01586	3.31e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IIGIHDMM_01587	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IIGIHDMM_01588	5.9e-282	arcT	-	-	E	-	-	-	Aminotransferase
IIGIHDMM_01589	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IIGIHDMM_01590	0.0	potE	-	-	E	-	-	-	Amino Acid
IIGIHDMM_01591	2.05e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IIGIHDMM_01592	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IIGIHDMM_01593	2.53e-42	-	-	-	-	-	-	-	-
IIGIHDMM_01594	7.34e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IIGIHDMM_01595	3.86e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IIGIHDMM_01596	2.67e-223	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IIGIHDMM_01597	6.93e-154	-	-	-	M	-	-	-	Bacterial sugar transferase
IIGIHDMM_01598	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
IIGIHDMM_01599	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
IIGIHDMM_01600	3.89e-47	-	-	-	-	-	-	-	-
IIGIHDMM_01601	1.44e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IIGIHDMM_01602	8.02e-271	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IIGIHDMM_01603	8.97e-96	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
IIGIHDMM_01604	3.45e-148	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IIGIHDMM_01605	5.37e-130	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IIGIHDMM_01606	2.85e-114	cps3F	-	-	-	-	-	-	-
IIGIHDMM_01607	1.32e-54	-	-	-	M	-	-	-	biosynthesis protein
IIGIHDMM_01608	2.47e-108	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IIGIHDMM_01609	1.77e-113	-	-	-	S	-	-	-	Glycosyltransferase like family
IIGIHDMM_01610	6.57e-165	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
IIGIHDMM_01611	1.13e-91	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IIGIHDMM_01612	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIGIHDMM_01614	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_01615	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_01617	6.43e-95	-	-	-	-	-	-	-	-
IIGIHDMM_01618	2.71e-36	-	-	-	-	-	-	-	-
IIGIHDMM_01619	3.93e-181	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IIGIHDMM_01620	2.48e-161	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIGIHDMM_01621	2.89e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IIGIHDMM_01622	2.14e-91	-	-	-	-	-	-	-	-
IIGIHDMM_01623	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIGIHDMM_01624	1.19e-134	-	-	-	L	-	-	-	nuclease
IIGIHDMM_01625	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
IIGIHDMM_01626	4.55e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIGIHDMM_01627	1.18e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
IIGIHDMM_01628	7.76e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IIGIHDMM_01630	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
IIGIHDMM_01631	4.36e-90	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
IIGIHDMM_01633	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IIGIHDMM_01634	1.08e-218	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IIGIHDMM_01635	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
IIGIHDMM_01636	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
IIGIHDMM_01637	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
IIGIHDMM_01638	1.6e-28	-	-	-	S	-	-	-	Acyltransferase family
IIGIHDMM_01640	2.08e-54	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
IIGIHDMM_01641	3.7e-34	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IIGIHDMM_01642	1.29e-37	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
IIGIHDMM_01643	7.07e-32	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IIGIHDMM_01644	1.2e-83	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IIGIHDMM_01646	7.59e-47	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
IIGIHDMM_01647	2.94e-82	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
IIGIHDMM_01648	3.77e-105	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
IIGIHDMM_01649	2.77e-61	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
IIGIHDMM_01650	4.91e-135	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IIGIHDMM_01651	3.74e-127	epsB	-	-	M	-	-	-	biosynthesis protein
IIGIHDMM_01653	7.42e-05	-	-	-	G	-	-	-	domain, Protein
IIGIHDMM_01654	0.000524	-	-	-	G	-	-	-	domain, Protein
IIGIHDMM_01655	1.21e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIGIHDMM_01656	2.88e-229	-	-	-	-	-	-	-	-
IIGIHDMM_01657	3.05e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIGIHDMM_01658	3.5e-311	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IIGIHDMM_01659	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IIGIHDMM_01660	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIGIHDMM_01661	2.55e-246	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IIGIHDMM_01662	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIGIHDMM_01663	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIGIHDMM_01664	3.29e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIGIHDMM_01665	3.28e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIGIHDMM_01666	4.3e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IIGIHDMM_01667	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIGIHDMM_01668	1.44e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIGIHDMM_01669	3e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIGIHDMM_01670	8.37e-171	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
IIGIHDMM_01671	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IIGIHDMM_01672	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IIGIHDMM_01673	1.5e-220	ydbI	-	-	K	-	-	-	AI-2E family transporter
IIGIHDMM_01674	1.54e-293	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IIGIHDMM_01675	1.76e-146	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IIGIHDMM_01676	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIGIHDMM_01677	1.61e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIGIHDMM_01678	5.59e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIGIHDMM_01679	1.83e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIGIHDMM_01680	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IIGIHDMM_01681	3.33e-187	-	-	-	K	-	-	-	LysR substrate binding domain
IIGIHDMM_01682	8.18e-70	-	-	-	S	-	-	-	branched-chain amino acid
IIGIHDMM_01683	5.63e-185	-	-	-	E	-	-	-	AzlC protein
IIGIHDMM_01684	2.25e-265	hpk31	-	-	T	-	-	-	Histidine kinase
IIGIHDMM_01685	9.76e-161	vanR	-	-	K	-	-	-	response regulator
IIGIHDMM_01686	7.28e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIGIHDMM_01687	2.88e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
IIGIHDMM_01688	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IIGIHDMM_01689	1.16e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
IIGIHDMM_01690	2.8e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIGIHDMM_01691	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIGIHDMM_01692	4.44e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IIGIHDMM_01693	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIGIHDMM_01694	4.78e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IIGIHDMM_01695	3.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IIGIHDMM_01696	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IIGIHDMM_01697	1.02e-197	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IIGIHDMM_01698	2.02e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IIGIHDMM_01699	2.08e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
IIGIHDMM_01700	1.67e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IIGIHDMM_01701	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
IIGIHDMM_01702	5.3e-287	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IIGIHDMM_01703	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01704	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGIHDMM_01705	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIGIHDMM_01706	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_01708	2.92e-145	-	-	-	I	-	-	-	Acid phosphatase homologues
IIGIHDMM_01709	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
IIGIHDMM_01710	4.13e-294	-	-	-	P	-	-	-	Chloride transporter, ClC family
IIGIHDMM_01711	6.39e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IIGIHDMM_01712	6.12e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IIGIHDMM_01713	6.79e-181	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IIGIHDMM_01714	4.3e-68	-	-	-	-	-	-	-	-
IIGIHDMM_01715	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
IIGIHDMM_01716	1.48e-114	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IIGIHDMM_01717	1.36e-17	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IIGIHDMM_01718	8.64e-97	-	-	-	-	-	-	-	-
IIGIHDMM_01719	1.05e-225	-	-	-	-	-	-	-	-
IIGIHDMM_01720	9.99e-225	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IIGIHDMM_01721	9.41e-162	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IIGIHDMM_01722	2.06e-164	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIGIHDMM_01723	2.64e-103	-	-	-	S	-	-	-	Flavodoxin
IIGIHDMM_01724	6.31e-82	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
IIGIHDMM_01725	2.17e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
IIGIHDMM_01726	1.51e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
IIGIHDMM_01727	2.69e-185	-	-	-	H	-	-	-	geranyltranstransferase activity
IIGIHDMM_01728	1.04e-222	-	-	-	-	-	-	-	-
IIGIHDMM_01729	1.26e-25	-	-	-	-	-	-	-	-
IIGIHDMM_01730	5.03e-148	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
IIGIHDMM_01731	1.55e-232	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
IIGIHDMM_01732	1.76e-57	-	-	-	-	-	-	-	-
IIGIHDMM_01733	3.74e-123	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IIGIHDMM_01734	1.3e-96	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IIGIHDMM_01735	4.07e-287	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
IIGIHDMM_01736	2.01e-108	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IIGIHDMM_01737	3.87e-238	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
IIGIHDMM_01738	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIGIHDMM_01739	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
IIGIHDMM_01740	2.85e-128	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
IIGIHDMM_01741	1.91e-167	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
IIGIHDMM_01742	2.29e-197	-	-	-	EG	-	-	-	EamA-like transporter family
IIGIHDMM_01743	1.15e-152	-	-	-	L	-	-	-	Integrase
IIGIHDMM_01744	1.78e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
IIGIHDMM_01745	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIGIHDMM_01747	3.42e-92	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIGIHDMM_01748	1.94e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IIGIHDMM_01749	1.55e-225	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIGIHDMM_01750	1.02e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIGIHDMM_01751	3.11e-200	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IIGIHDMM_01752	8.61e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IIGIHDMM_01753	5.75e-285	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIGIHDMM_01754	6.67e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIGIHDMM_01755	9.31e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIGIHDMM_01756	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IIGIHDMM_01757	6.9e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIGIHDMM_01758	1.61e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IIGIHDMM_01759	4.96e-171	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IIGIHDMM_01768	4.5e-73	-	-	-	-	-	-	-	-
IIGIHDMM_01769	2.14e-148	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
IIGIHDMM_01770	6.9e-207	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IIGIHDMM_01771	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IIGIHDMM_01772	4.22e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
IIGIHDMM_01774	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_01775	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_01776	6.47e-157	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
IIGIHDMM_01777	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
IIGIHDMM_01779	1.08e-67	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
IIGIHDMM_01780	1.22e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIGIHDMM_01781	5.43e-311	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
IIGIHDMM_01782	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IIGIHDMM_01783	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIGIHDMM_01784	1.91e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
IIGIHDMM_01785	1.52e-139	-	-	-	M	-	-	-	LysM domain protein
IIGIHDMM_01786	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
IIGIHDMM_01787	2.28e-139	-	-	-	M	-	-	-	LysM domain protein
IIGIHDMM_01788	4.89e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IIGIHDMM_01789	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IIGIHDMM_01790	1.88e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
IIGIHDMM_01791	1.06e-195	yeaE	-	-	S	-	-	-	Aldo keto
IIGIHDMM_01792	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IIGIHDMM_01793	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
IIGIHDMM_01794	4.58e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IIGIHDMM_01795	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IIGIHDMM_01796	7.03e-33	-	-	-	-	-	-	-	-
IIGIHDMM_01797	8.28e-135	-	-	-	V	-	-	-	VanZ like family
IIGIHDMM_01798	3.47e-303	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IIGIHDMM_01799	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IIGIHDMM_01800	0.0	-	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_01801	1.1e-121	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
IIGIHDMM_01802	1.57e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIGIHDMM_01803	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IIGIHDMM_01804	5.07e-56	-	-	-	-	-	-	-	-
IIGIHDMM_01805	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IIGIHDMM_01806	1.68e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIGIHDMM_01807	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IIGIHDMM_01808	5.35e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
IIGIHDMM_01809	1.41e-227	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIGIHDMM_01810	6.18e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
IIGIHDMM_01811	1.47e-144	-	-	-	-	-	-	-	-
IIGIHDMM_01812	4.87e-236	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
IIGIHDMM_01813	2.42e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIGIHDMM_01814	1.52e-43	-	-	-	-	-	-	-	-
IIGIHDMM_01815	3.02e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IIGIHDMM_01816	9.17e-59	-	-	-	-	-	-	-	-
IIGIHDMM_01818	1.09e-35	-	-	-	-	-	-	-	-
IIGIHDMM_01819	1.17e-31	-	-	-	-	-	-	-	-
IIGIHDMM_01820	8.69e-185	-	-	-	S	-	-	-	Domain of unknown function DUF1829
IIGIHDMM_01821	7.96e-94	-	-	-	-	-	-	-	-
IIGIHDMM_01822	1.43e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIGIHDMM_01823	3.74e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IIGIHDMM_01824	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
IIGIHDMM_01825	1.54e-289	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIGIHDMM_01826	4.06e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
IIGIHDMM_01827	1.56e-275	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
IIGIHDMM_01828	4.61e-61	-	-	-	-	-	-	-	-
IIGIHDMM_01829	1.49e-54	-	-	-	-	-	-	-	-
IIGIHDMM_01831	9.95e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIGIHDMM_01832	6.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IIGIHDMM_01833	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IIGIHDMM_01834	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IIGIHDMM_01835	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IIGIHDMM_01836	5.06e-280	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
IIGIHDMM_01837	0.0	yhaN	-	-	L	-	-	-	AAA domain
IIGIHDMM_01838	1.22e-177	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIGIHDMM_01840	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
IIGIHDMM_01841	2.7e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01842	7.75e-278	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IIGIHDMM_01843	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIGIHDMM_01844	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IIGIHDMM_01845	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IIGIHDMM_01846	7.44e-232	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IIGIHDMM_01847	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IIGIHDMM_01848	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
IIGIHDMM_01849	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
IIGIHDMM_01850	3.85e-151	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIGIHDMM_01851	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IIGIHDMM_01852	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IIGIHDMM_01853	9.73e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIGIHDMM_01854	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIGIHDMM_01855	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIGIHDMM_01856	7.5e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIGIHDMM_01857	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIGIHDMM_01858	4.9e-301	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
IIGIHDMM_01859	6.77e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IIGIHDMM_01860	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIGIHDMM_01861	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IIGIHDMM_01862	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIGIHDMM_01863	1.34e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
IIGIHDMM_01864	4.47e-278	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IIGIHDMM_01865	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IIGIHDMM_01866	1.46e-159	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIGIHDMM_01867	8.83e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IIGIHDMM_01868	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIGIHDMM_01869	7.76e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
IIGIHDMM_01870	4.61e-272	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IIGIHDMM_01871	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IIGIHDMM_01872	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IIGIHDMM_01873	1.38e-155	csrR	-	-	K	-	-	-	response regulator
IIGIHDMM_01874	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIGIHDMM_01875	0.0	potE	-	-	E	-	-	-	Amino Acid
IIGIHDMM_01876	1.22e-291	-	-	-	V	-	-	-	MatE
IIGIHDMM_01877	5.31e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIGIHDMM_01878	3.19e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIGIHDMM_01879	4.22e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IIGIHDMM_01880	3.84e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIGIHDMM_01881	7.57e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IIGIHDMM_01882	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGIHDMM_01883	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIGIHDMM_01884	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIGIHDMM_01885	5.07e-150	-	-	-	M	-	-	-	PFAM NLP P60 protein
IIGIHDMM_01886	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IIGIHDMM_01887	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIGIHDMM_01888	5.43e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IIGIHDMM_01889	0.0	-	-	-	S	-	-	-	membrane
IIGIHDMM_01890	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IIGIHDMM_01891	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IIGIHDMM_01892	1.55e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIGIHDMM_01893	2.39e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
IIGIHDMM_01894	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IIGIHDMM_01895	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IIGIHDMM_01896	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IIGIHDMM_01897	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IIGIHDMM_01898	2.79e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIGIHDMM_01899	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IIGIHDMM_01900	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIGIHDMM_01901	8e-276	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIGIHDMM_01902	1.28e-18	-	-	-	-	-	-	-	-
IIGIHDMM_01903	5.91e-198	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IIGIHDMM_01904	6.67e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIGIHDMM_01905	1.27e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IIGIHDMM_01906	4.87e-203	-	-	-	-	-	-	-	-
IIGIHDMM_01907	9.04e-234	-	-	-	-	-	-	-	-
IIGIHDMM_01908	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
IIGIHDMM_01911	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_01912	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IIGIHDMM_01913	8.76e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
IIGIHDMM_01914	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IIGIHDMM_01915	5.24e-168	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IIGIHDMM_01916	1.34e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IIGIHDMM_01917	5.18e-149	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
IIGIHDMM_01918	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IIGIHDMM_01919	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIGIHDMM_01920	9.32e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIGIHDMM_01921	4.45e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIGIHDMM_01922	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIGIHDMM_01923	4.9e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIGIHDMM_01924	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IIGIHDMM_01925	4.54e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIGIHDMM_01926	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IIGIHDMM_01927	9e-72	-	-	-	-	-	-	-	-
IIGIHDMM_01928	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IIGIHDMM_01929	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IIGIHDMM_01930	7.68e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIGIHDMM_01931	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIGIHDMM_01932	2.47e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIGIHDMM_01933	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIGIHDMM_01934	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IIGIHDMM_01935	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IIGIHDMM_01936	1.26e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIGIHDMM_01937	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IIGIHDMM_01938	2.24e-155	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IIGIHDMM_01939	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IIGIHDMM_01940	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IIGIHDMM_01941	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IIGIHDMM_01942	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIGIHDMM_01943	5.75e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIGIHDMM_01944	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIGIHDMM_01945	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIGIHDMM_01946	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IIGIHDMM_01947	1.1e-274	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIGIHDMM_01948	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIGIHDMM_01949	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIGIHDMM_01950	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IIGIHDMM_01951	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IIGIHDMM_01952	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIGIHDMM_01953	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IIGIHDMM_01954	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
IIGIHDMM_01955	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIGIHDMM_01956	1.28e-46	-	-	-	-	-	-	-	-
IIGIHDMM_01957	5.01e-69	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
IIGIHDMM_01958	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IIGIHDMM_01959	7.7e-110	-	-	-	-	-	-	-	-
IIGIHDMM_01960	3.31e-239	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IIGIHDMM_01961	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IIGIHDMM_01962	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
IIGIHDMM_01963	5.18e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIGIHDMM_01964	1.15e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
IIGIHDMM_01965	1.91e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
IIGIHDMM_01966	1.99e-283	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IIGIHDMM_01967	1.06e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IIGIHDMM_01968	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
IIGIHDMM_01969	1.66e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
IIGIHDMM_01970	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIGIHDMM_01972	1.34e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
IIGIHDMM_01973	2.89e-194	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IIGIHDMM_01974	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
IIGIHDMM_01975	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
IIGIHDMM_01976	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
IIGIHDMM_01979	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
IIGIHDMM_01980	2.9e-275	-	-	-	L	-	-	-	Integrase core domain
IIGIHDMM_01981	5.75e-242	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGIHDMM_01982	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_01983	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IIGIHDMM_01984	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGIHDMM_01985	1.16e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIGIHDMM_01986	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IIGIHDMM_01987	2.05e-160	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
IIGIHDMM_01988	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IIGIHDMM_01989	1.05e-310	-	-	-	E	-	-	-	amino acid
IIGIHDMM_01990	1.29e-179	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
IIGIHDMM_01991	3.4e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IIGIHDMM_01992	1.86e-214	-	-	-	GK	-	-	-	ROK family
IIGIHDMM_01993	0.0	fusA1	-	-	J	-	-	-	elongation factor G
IIGIHDMM_01994	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
IIGIHDMM_01995	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IIGIHDMM_01996	2.43e-81	-	-	-	-	-	-	-	-
IIGIHDMM_01997	3.18e-11	-	-	-	-	-	-	-	-
IIGIHDMM_01998	1.41e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IIGIHDMM_01999	1.37e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IIGIHDMM_02000	9.65e-271	-	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_02001	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
IIGIHDMM_02002	4.84e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
IIGIHDMM_02003	1.72e-207	-	-	-	-	-	-	-	-
IIGIHDMM_02004	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
IIGIHDMM_02005	4.31e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IIGIHDMM_02006	2.59e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
IIGIHDMM_02007	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
IIGIHDMM_02008	6.5e-71	-	-	-	-	-	-	-	-
IIGIHDMM_02009	3.54e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IIGIHDMM_02010	3.61e-316	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIGIHDMM_02011	4.97e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IIGIHDMM_02012	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IIGIHDMM_02013	7.72e-178	-	-	-	IQ	-	-	-	KR domain
IIGIHDMM_02014	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
IIGIHDMM_02015	4.85e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IIGIHDMM_02016	9.63e-114	-	-	-	S	-	-	-	Double zinc ribbon
IIGIHDMM_02017	5.6e-176	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IIGIHDMM_02018	6.21e-168	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IIGIHDMM_02019	3.66e-21	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IIGIHDMM_02020	1.09e-27	-	-	-	D	-	-	-	transport
IIGIHDMM_02021	3.73e-24	-	-	-	-	-	-	-	-
IIGIHDMM_02022	2.22e-212	-	-	-	-	-	-	-	-
IIGIHDMM_02024	9.64e-13	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
IIGIHDMM_02025	3.31e-30	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IIGIHDMM_02027	1.1e-193	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IIGIHDMM_02028	1.67e-42	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IIGIHDMM_02029	1.9e-147	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IIGIHDMM_02030	4.32e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
IIGIHDMM_02031	0.0	yagE	-	-	E	-	-	-	amino acid
IIGIHDMM_02032	2.93e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IIGIHDMM_02033	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IIGIHDMM_02034	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IIGIHDMM_02035	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIGIHDMM_02036	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IIGIHDMM_02037	1.01e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGIHDMM_02038	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IIGIHDMM_02039	5.98e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIGIHDMM_02040	6.86e-294	-	-	-	-	-	-	-	-
IIGIHDMM_02041	5.07e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
IIGIHDMM_02042	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
IIGIHDMM_02043	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
IIGIHDMM_02044	6.8e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
IIGIHDMM_02045	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IIGIHDMM_02046	6.12e-28	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
IIGIHDMM_02047	1.14e-193	-	-	-	-	-	-	-	-
IIGIHDMM_02048	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
IIGIHDMM_02049	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
IIGIHDMM_02050	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
IIGIHDMM_02051	2.3e-230	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIGIHDMM_02052	4.56e-10	-	-	-	S	-	-	-	CsbD-like
IIGIHDMM_02053	1.98e-42	-	-	-	S	-	-	-	Transglycosylase associated protein
IIGIHDMM_02054	1.49e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIGIHDMM_02055	3.87e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
IIGIHDMM_02056	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
IIGIHDMM_02057	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IIGIHDMM_02058	3.14e-310	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IIGIHDMM_02059	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
IIGIHDMM_02060	6.71e-207	-	-	-	EG	-	-	-	EamA-like transporter family
IIGIHDMM_02061	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIGIHDMM_02062	4.12e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IIGIHDMM_02063	1.07e-282	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
IIGIHDMM_02065	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IIGIHDMM_02066	1.3e-282	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IIGIHDMM_02067	5.48e-202	-	-	-	J	-	-	-	Methyltransferase
IIGIHDMM_02068	3.14e-86	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
IIGIHDMM_02069	8.79e-156	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIGIHDMM_02070	2.59e-80	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IIGIHDMM_02071	7.68e-129	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain
IIGIHDMM_02072	2.11e-165	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
IIGIHDMM_02073	2.93e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
IIGIHDMM_02074	2.89e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIGIHDMM_02075	3.47e-121	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
IIGIHDMM_02076	4.36e-127	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IIGIHDMM_02077	8.17e-250	-	-	-	EGP	-	-	-	Major Facilitator
IIGIHDMM_02078	4.72e-168	-	-	-	M	-	-	-	Lysin motif
IIGIHDMM_02079	5.69e-105	-	-	-	-	-	-	-	-
IIGIHDMM_02080	4.93e-214	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IIGIHDMM_02081	4.89e-122	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
IIGIHDMM_02082	5.2e-122	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
IIGIHDMM_02083	3.53e-257	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
IIGIHDMM_02084	3.7e-19	-	-	-	-	-	-	-	-
IIGIHDMM_02085	2.11e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
IIGIHDMM_02089	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIGIHDMM_02090	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IIGIHDMM_02091	1.1e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IIGIHDMM_02092	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIGIHDMM_02093	2.73e-107	-	-	-	-	-	-	-	-
IIGIHDMM_02094	1.96e-49	-	-	-	-	-	-	-	-
IIGIHDMM_02095	3.35e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IIGIHDMM_02096	2.12e-165	-	-	-	-	-	-	-	-
IIGIHDMM_02097	2.56e-86	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IIGIHDMM_02098	3.82e-214	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIGIHDMM_02099	7.12e-180	epsB	-	-	M	-	-	-	biosynthesis protein
IIGIHDMM_02100	3.36e-152	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IIGIHDMM_02101	7.91e-175	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
IIGIHDMM_02102	2.91e-106	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
IIGIHDMM_02103	7.87e-95	-	-	-	M	-	-	-	Glycosyl transferase family 2
IIGIHDMM_02104	8.37e-41	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IIGIHDMM_02105	1.64e-68	-	-	-	S	-	-	-	Glycosyl transferase family 2
IIGIHDMM_02106	3.48e-75	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IIGIHDMM_02107	2.73e-39	-	-	-	M	-	-	-	Glycosyltransferase like family 2
IIGIHDMM_02109	2.22e-46	-	-	-	S	ko:K16710	-	ko00000	Polysaccharide pyruvyl transferase
IIGIHDMM_02110	3.83e-153	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
IIGIHDMM_02111	6.8e-22	-	2.3.1.18	-	S	ko:K00633	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
IIGIHDMM_02112	1.37e-78	-	-	-	S	-	-	-	Core-2/I-Branching enzyme