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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFFKCMKK_00001	3.31e-110	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HFFKCMKK_00003	4.44e-214	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HFFKCMKK_00004	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HFFKCMKK_00005	5.88e-19	-	-	-	-	-	-	-	-
HFFKCMKK_00007	2.11e-40	-	-	-	L	-	-	-	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HFFKCMKK_00011	3.23e-177	-	-	-	-	-	-	-	-
HFFKCMKK_00012	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFFKCMKK_00014	1.03e-37	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFFKCMKK_00015	1.15e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HFFKCMKK_00016	8.66e-89	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFFKCMKK_00017	1.5e-241	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFFKCMKK_00018	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HFFKCMKK_00019	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HFFKCMKK_00020	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HFFKCMKK_00021	3.66e-183	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HFFKCMKK_00023	3.13e-164	-	-	-	M	-	-	-	PFAM NLP P60 protein
HFFKCMKK_00024	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFFKCMKK_00025	5.58e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFFKCMKK_00026	1.61e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00027	1.93e-119	-	-	-	P	-	-	-	Cadmium resistance transporter
HFFKCMKK_00028	2.29e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HFFKCMKK_00029	2.82e-94	-	-	-	M	-	-	-	domain protein
HFFKCMKK_00030	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HFFKCMKK_00031	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFFKCMKK_00032	2.19e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HFFKCMKK_00033	1.21e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFFKCMKK_00034	6.47e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFFKCMKK_00035	7.36e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFFKCMKK_00036	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFKCMKK_00037	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFFKCMKK_00038	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFFKCMKK_00039	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFKCMKK_00040	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HFFKCMKK_00043	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HFFKCMKK_00044	2.49e-43	-	-	-	-	-	-	-	-
HFFKCMKK_00045	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFKCMKK_00046	3.24e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFKCMKK_00047	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HFFKCMKK_00049	1.79e-84	-	-	-	-	-	-	-	-
HFFKCMKK_00050	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFFKCMKK_00051	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFFKCMKK_00052	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFFKCMKK_00053	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFFKCMKK_00054	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFFKCMKK_00055	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFKCMKK_00056	1.01e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HFFKCMKK_00058	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFKCMKK_00059	1.95e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HFFKCMKK_00060	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFFKCMKK_00061	9.8e-305	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFFKCMKK_00062	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFFKCMKK_00063	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HFFKCMKK_00064	1.77e-56	-	-	-	-	-	-	-	-
HFFKCMKK_00065	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFFKCMKK_00066	2.84e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HFFKCMKK_00067	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
HFFKCMKK_00068	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFFKCMKK_00069	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFFKCMKK_00070	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFFKCMKK_00071	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFFKCMKK_00072	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFFKCMKK_00073	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFFKCMKK_00074	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFFKCMKK_00075	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HFFKCMKK_00076	2.23e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFFKCMKK_00077	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFFKCMKK_00078	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFFKCMKK_00079	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HFFKCMKK_00080	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFFKCMKK_00081	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFFKCMKK_00082	7.61e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFFKCMKK_00083	6.02e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFFKCMKK_00084	4.75e-132	-	-	-	-	-	-	-	-
HFFKCMKK_00086	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFFKCMKK_00087	9.09e-142	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HFFKCMKK_00088	3.7e-297	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFFKCMKK_00089	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HFFKCMKK_00090	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
HFFKCMKK_00091	1.61e-50	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HFFKCMKK_00092	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFFKCMKK_00093	2.42e-141	isp	-	-	L	-	-	-	Transposase
HFFKCMKK_00094	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HFFKCMKK_00095	1.1e-63	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00096	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00097	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFFKCMKK_00098	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HFFKCMKK_00102	0.0	-	-	-	L	-	-	-	helicase activity
HFFKCMKK_00103	2.66e-275	-	-	-	K	-	-	-	DNA binding
HFFKCMKK_00104	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HFFKCMKK_00105	3.04e-29	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HFFKCMKK_00106	6.08e-249	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HFFKCMKK_00107	9.9e-49	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFFKCMKK_00108	5.31e-169	-	-	-	-	-	-	-	-
HFFKCMKK_00109	1.33e-121	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HFFKCMKK_00110	3.81e-62	-	-	-	-	-	-	-	-
HFFKCMKK_00112	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFFKCMKK_00113	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HFFKCMKK_00114	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HFFKCMKK_00115	1.16e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
HFFKCMKK_00116	7.41e-120	-	-	-	-	-	-	-	-
HFFKCMKK_00117	1.77e-157	pnb	-	-	C	-	-	-	nitroreductase
HFFKCMKK_00118	5.68e-95	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HFFKCMKK_00119	4.76e-217	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HFFKCMKK_00120	1.31e-213	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HFFKCMKK_00121	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HFFKCMKK_00122	1.74e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFFKCMKK_00123	1.2e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFFKCMKK_00124	5.18e-27	-	-	-	-	-	-	-	-
HFFKCMKK_00125	8.83e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFFKCMKK_00126	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HFFKCMKK_00127	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HFFKCMKK_00128	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HFFKCMKK_00129	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFFKCMKK_00130	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HFFKCMKK_00131	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HFFKCMKK_00132	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HFFKCMKK_00133	7.43e-295	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HFFKCMKK_00135	8.5e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFFKCMKK_00136	2.02e-72	-	-	-	-	-	-	-	-
HFFKCMKK_00139	2.02e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HFFKCMKK_00140	0.0	-	-	-	L	-	-	-	DNA helicase
HFFKCMKK_00141	1.1e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFFKCMKK_00143	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFFKCMKK_00144	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HFFKCMKK_00145	4.89e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFFKCMKK_00146	3.74e-58	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HFFKCMKK_00147	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HFFKCMKK_00148	1.47e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HFFKCMKK_00149	3.24e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HFFKCMKK_00150	1.97e-198	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFFKCMKK_00151	2.11e-151	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFKCMKK_00152	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFFKCMKK_00153	1.47e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFFKCMKK_00154	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00155	8.7e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFFKCMKK_00156	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFFKCMKK_00157	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFFKCMKK_00158	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HFFKCMKK_00159	8.34e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00160	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00161	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HFFKCMKK_00162	3.87e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_00163	1.83e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
HFFKCMKK_00164	4.44e-11	-	-	-	-	-	-	-	-
HFFKCMKK_00165	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HFFKCMKK_00166	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HFFKCMKK_00167	1.2e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_00168	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFFKCMKK_00169	1.89e-80	-	-	-	-	-	-	-	-
HFFKCMKK_00170	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFFKCMKK_00171	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HFFKCMKK_00172	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HFFKCMKK_00173	2.39e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00174	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00175	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00176	1.18e-50	-	-	-	-	-	-	-	-
HFFKCMKK_00177	4.57e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HFFKCMKK_00178	7.15e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFFKCMKK_00179	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFKCMKK_00180	2.14e-32	-	-	-	-	-	-	-	-
HFFKCMKK_00181	1.03e-146	-	-	-	-	-	-	-	-
HFFKCMKK_00182	4.99e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_00183	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFFKCMKK_00184	2.46e-113	-	-	-	-	-	-	-	-
HFFKCMKK_00185	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HFFKCMKK_00186	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFFKCMKK_00187	1.2e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_00188	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFFKCMKK_00189	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFKCMKK_00190	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00192	1.77e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFFKCMKK_00193	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HFFKCMKK_00194	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HFFKCMKK_00195	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HFFKCMKK_00196	6.29e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HFFKCMKK_00197	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFFKCMKK_00198	4.63e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HFFKCMKK_00199	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFFKCMKK_00200	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HFFKCMKK_00201	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFFKCMKK_00202	1.73e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HFFKCMKK_00203	3.97e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFFKCMKK_00204	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFFKCMKK_00205	1.58e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HFFKCMKK_00206	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HFFKCMKK_00207	5.36e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HFFKCMKK_00208	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFFKCMKK_00209	3.27e-159	vanR	-	-	K	-	-	-	response regulator
HFFKCMKK_00210	9.06e-260	hpk31	-	-	T	-	-	-	Histidine kinase
HFFKCMKK_00211	4.95e-195	-	-	-	E	-	-	-	AzlC protein
HFFKCMKK_00212	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HFFKCMKK_00213	3.11e-63	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HFFKCMKK_00214	2.79e-179	-	-	-	K	-	-	-	LysR substrate binding domain
HFFKCMKK_00215	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFFKCMKK_00216	4.45e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFFKCMKK_00217	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFFKCMKK_00218	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFFKCMKK_00219	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFFKCMKK_00220	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFFKCMKK_00221	4.34e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HFFKCMKK_00222	1.15e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFFKCMKK_00223	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFFKCMKK_00224	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HFFKCMKK_00225	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFFKCMKK_00226	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HFFKCMKK_00227	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFFKCMKK_00228	2.66e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFFKCMKK_00229	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFFKCMKK_00230	2.13e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFFKCMKK_00231	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFKCMKK_00232	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFKCMKK_00233	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFKCMKK_00234	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFFKCMKK_00235	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFFKCMKK_00236	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFFKCMKK_00237	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFFKCMKK_00238	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFFKCMKK_00239	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFFKCMKK_00240	1.99e-302	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HFFKCMKK_00241	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFKCMKK_00244	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00245	2.61e-211	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HFFKCMKK_00246	2.93e-117	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HFFKCMKK_00247	0.0	-	-	-	L	-	-	-	PLD-like domain
HFFKCMKK_00249	4.47e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HFFKCMKK_00250	2.44e-72	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFFKCMKK_00251	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFKCMKK_00252	8.53e-120	-	-	-	-	-	-	-	-
HFFKCMKK_00253	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFFKCMKK_00254	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HFFKCMKK_00255	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HFFKCMKK_00256	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFKCMKK_00257	1.51e-207	-	-	-	-	-	-	-	-
HFFKCMKK_00258	1.92e-202	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HFFKCMKK_00259	1.32e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HFFKCMKK_00260	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
HFFKCMKK_00261	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_00262	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFFKCMKK_00263	1.83e-113	-	-	-	GM	-	-	-	epimerase
HFFKCMKK_00264	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
HFFKCMKK_00265	1.67e-307	yhdP	-	-	S	-	-	-	Transporter associated domain
HFFKCMKK_00266	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HFFKCMKK_00267	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HFFKCMKK_00268	2.64e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HFFKCMKK_00269	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFFKCMKK_00270	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFFKCMKK_00271	6e-39	-	-	-	-	-	-	-	-
HFFKCMKK_00274	1.08e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HFFKCMKK_00277	2.37e-179	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
HFFKCMKK_00278	5.68e-61	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HFFKCMKK_00279	6.17e-13	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HFFKCMKK_00282	5.77e-21	-	-	-	K	-	-	-	ORF6N domain
HFFKCMKK_00283	7.47e-25	-	-	-	D	-	-	-	Glucan-binding protein C
HFFKCMKK_00284	3.43e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFFKCMKK_00285	5.75e-242	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFKCMKK_00286	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00287	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFFKCMKK_00288	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFKCMKK_00289	4.73e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFFKCMKK_00290	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HFFKCMKK_00291	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFFKCMKK_00292	1.05e-310	-	-	-	E	-	-	-	amino acid
HFFKCMKK_00293	4.49e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HFFKCMKK_00294	9.75e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFFKCMKK_00295	2.17e-213	-	-	-	GK	-	-	-	ROK family
HFFKCMKK_00296	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HFFKCMKK_00297	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HFFKCMKK_00298	1.37e-246	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HFFKCMKK_00299	1.78e-83	-	-	-	-	-	-	-	-
HFFKCMKK_00300	3.18e-11	-	-	-	-	-	-	-	-
HFFKCMKK_00301	6.79e-271	-	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_00302	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HFFKCMKK_00303	9.77e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HFFKCMKK_00304	3.46e-207	-	-	-	-	-	-	-	-
HFFKCMKK_00305	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_00306	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFFKCMKK_00307	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HFFKCMKK_00308	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFKCMKK_00309	6.5e-71	-	-	-	-	-	-	-	-
HFFKCMKK_00310	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFFKCMKK_00311	2.8e-315	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00312	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HFFKCMKK_00313	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFFKCMKK_00314	7.72e-178	-	-	-	IQ	-	-	-	KR domain
HFFKCMKK_00315	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HFFKCMKK_00316	1.14e-231	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFFKCMKK_00317	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_00318	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00319	1.53e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFKCMKK_00320	4.59e-40	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HFFKCMKK_00321	5.49e-183	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
HFFKCMKK_00323	5.99e-13	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFFKCMKK_00326	8.79e-81	-	-	-	-	-	-	-	-
HFFKCMKK_00329	5.9e-14	-	-	-	T	-	-	-	SpoVT / AbrB like domain
HFFKCMKK_00330	5.13e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFFKCMKK_00331	1.7e-20	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HFFKCMKK_00332	2.21e-23	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HFFKCMKK_00336	1.93e-66	-	-	-	L	-	-	-	four-way junction helicase activity
HFFKCMKK_00337	1.53e-61	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
HFFKCMKK_00338	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFFKCMKK_00339	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFFKCMKK_00340	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFFKCMKK_00341	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HFFKCMKK_00342	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HFFKCMKK_00343	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HFFKCMKK_00344	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HFFKCMKK_00345	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFFKCMKK_00346	2.1e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HFFKCMKK_00347	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HFFKCMKK_00348	4.79e-273	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HFFKCMKK_00349	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFFKCMKK_00350	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HFFKCMKK_00351	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HFFKCMKK_00352	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HFFKCMKK_00353	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFFKCMKK_00354	3.4e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFFKCMKK_00355	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HFFKCMKK_00356	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HFFKCMKK_00357	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HFFKCMKK_00358	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HFFKCMKK_00359	4.43e-191	-	-	-	O	-	-	-	Band 7 protein
HFFKCMKK_00360	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HFFKCMKK_00361	3.19e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFFKCMKK_00362	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HFFKCMKK_00363	8e-145	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HFFKCMKK_00364	1.35e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFFKCMKK_00365	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFFKCMKK_00366	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HFFKCMKK_00367	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HFFKCMKK_00368	9.08e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFFKCMKK_00369	3.21e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HFFKCMKK_00370	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HFFKCMKK_00371	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HFFKCMKK_00372	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HFFKCMKK_00373	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFFKCMKK_00374	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFFKCMKK_00375	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HFFKCMKK_00376	3.37e-140	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HFFKCMKK_00377	1.46e-263	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HFFKCMKK_00378	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFFKCMKK_00379	4.08e-143	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HFFKCMKK_00380	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFFKCMKK_00381	2.64e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HFFKCMKK_00382	3.39e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HFFKCMKK_00383	5.59e-249	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFFKCMKK_00384	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00385	8.91e-92	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFFKCMKK_00386	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFFKCMKK_00387	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HFFKCMKK_00388	2.57e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HFFKCMKK_00389	1.5e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFFKCMKK_00390	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HFFKCMKK_00391	3e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFFKCMKK_00392	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HFFKCMKK_00393	1.41e-286	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFFKCMKK_00394	2.82e-133	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFFKCMKK_00395	2.61e-236	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFFKCMKK_00396	2.72e-91	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFFKCMKK_00397	4e-82	-	-	-	S	-	-	-	integral membrane protein
HFFKCMKK_00398	1.54e-63	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HFFKCMKK_00399	1.59e-27	-	-	-	-	-	-	-	-
HFFKCMKK_00400	2.63e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
HFFKCMKK_00401	2.12e-303	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFFKCMKK_00402	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFFKCMKK_00403	2.65e-92	cps3I	-	-	G	-	-	-	Acyltransferase family
HFFKCMKK_00404	9.2e-43	-	-	-	-	-	-	-	-
HFFKCMKK_00405	8.31e-138	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFFKCMKK_00406	2.19e-36	-	-	-	M	-	-	-	Peptidase_C39 like family
HFFKCMKK_00407	5.36e-97	-	-	-	-	-	-	-	-
HFFKCMKK_00408	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFFKCMKK_00409	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFFKCMKK_00410	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HFFKCMKK_00411	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFFKCMKK_00412	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFFKCMKK_00413	2.26e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFFKCMKK_00414	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFFKCMKK_00415	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HFFKCMKK_00416	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFFKCMKK_00417	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFFKCMKK_00418	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFFKCMKK_00419	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFFKCMKK_00420	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFFKCMKK_00421	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HFFKCMKK_00422	3.4e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HFFKCMKK_00423	1.23e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFFKCMKK_00424	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFFKCMKK_00425	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HFFKCMKK_00426	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HFFKCMKK_00427	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFFKCMKK_00428	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFFKCMKK_00429	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HFFKCMKK_00430	4.77e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HFFKCMKK_00431	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HFFKCMKK_00432	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFFKCMKK_00433	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HFFKCMKK_00434	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HFFKCMKK_00435	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFFKCMKK_00436	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_00437	3.74e-53	-	-	-	-	-	-	-	-
HFFKCMKK_00438	0.0	ydaO	-	-	E	-	-	-	amino acid
HFFKCMKK_00439	0.0	-	-	-	E	-	-	-	amino acid
HFFKCMKK_00440	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HFFKCMKK_00441	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFFKCMKK_00442	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFFKCMKK_00444	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFFKCMKK_00445	5.82e-79	-	-	-	-	-	-	-	-
HFFKCMKK_00447	9.76e-93	-	-	-	O	-	-	-	Preprotein translocase subunit SecB
HFFKCMKK_00448	5.14e-217	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HFFKCMKK_00449	8.9e-317	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFFKCMKK_00451	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HFFKCMKK_00452	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HFFKCMKK_00454	5.89e-82	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HFFKCMKK_00455	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HFFKCMKK_00457	0.0	snf	-	-	KL	-	-	-	domain protein
HFFKCMKK_00458	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HFFKCMKK_00459	3.74e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFFKCMKK_00460	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HFFKCMKK_00461	1.08e-23	-	-	-	L	-	-	-	nuclease
HFFKCMKK_00462	3.78e-73	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFFKCMKK_00463	6.12e-91	-	-	-	-	-	-	-	-
HFFKCMKK_00464	1.18e-134	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFFKCMKK_00465	2.66e-156	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFFKCMKK_00466	6.38e-195	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HFFKCMKK_00467	0.0	-	-	-	-	-	-	-	-
HFFKCMKK_00468	6.54e-108	-	-	-	-	-	-	-	-
HFFKCMKK_00469	0.0	-	-	-	-	-	-	-	-
HFFKCMKK_00471	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFFKCMKK_00473	7.02e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HFFKCMKK_00474	3.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFFKCMKK_00475	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFFKCMKK_00476	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
HFFKCMKK_00477	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HFFKCMKK_00478	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFFKCMKK_00479	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HFFKCMKK_00480	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HFFKCMKK_00481	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFFKCMKK_00482	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HFFKCMKK_00483	6.08e-13	-	-	-	S	-	-	-	CsbD-like
HFFKCMKK_00484	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFKCMKK_00485	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HFFKCMKK_00486	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HFFKCMKK_00487	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HFFKCMKK_00488	8.05e-194	-	-	-	-	-	-	-	-
HFFKCMKK_00489	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HFFKCMKK_00490	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HFFKCMKK_00491	1.12e-131	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HFFKCMKK_00492	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
HFFKCMKK_00493	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFFKCMKK_00494	1.77e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HFFKCMKK_00495	1.97e-293	-	-	-	-	-	-	-	-
HFFKCMKK_00496	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFKCMKK_00497	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00498	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00499	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFFKCMKK_00500	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFFKCMKK_00501	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFFKCMKK_00502	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFFKCMKK_00503	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HFFKCMKK_00504	0.0	yagE	-	-	E	-	-	-	amino acid
HFFKCMKK_00505	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HFFKCMKK_00506	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFFKCMKK_00507	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00508	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_00509	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFFKCMKK_00510	7.38e-232	-	-	-	-	-	-	-	-
HFFKCMKK_00511	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
HFFKCMKK_00512	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFFKCMKK_00513	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFFKCMKK_00514	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFFKCMKK_00515	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFFKCMKK_00516	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFFKCMKK_00517	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFFKCMKK_00518	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HFFKCMKK_00519	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFFKCMKK_00520	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
HFFKCMKK_00521	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFFKCMKK_00522	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFFKCMKK_00523	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
HFFKCMKK_00524	1.19e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HFFKCMKK_00525	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HFFKCMKK_00526	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HFFKCMKK_00527	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HFFKCMKK_00528	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFFKCMKK_00529	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFFKCMKK_00530	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HFFKCMKK_00531	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFKCMKK_00532	1.1e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HFFKCMKK_00533	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFKCMKK_00534	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFFKCMKK_00535	3.55e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HFFKCMKK_00536	1.29e-239	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HFFKCMKK_00537	2.29e-158	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00538	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFFKCMKK_00539	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFFKCMKK_00540	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFFKCMKK_00541	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HFFKCMKK_00542	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFFKCMKK_00543	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HFFKCMKK_00544	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HFFKCMKK_00545	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFKCMKK_00546	1.51e-289	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFFKCMKK_00547	1.75e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HFFKCMKK_00548	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFKCMKK_00549	3.07e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFKCMKK_00550	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFFKCMKK_00551	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFFKCMKK_00552	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HFFKCMKK_00553	4.85e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFFKCMKK_00554	6.98e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFKCMKK_00555	6.34e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HFFKCMKK_00556	4.25e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFFKCMKK_00557	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFFKCMKK_00558	2.55e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFFKCMKK_00559	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFFKCMKK_00560	2.9e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HFFKCMKK_00561	1.96e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HFFKCMKK_00562	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00567	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFFKCMKK_00568	1.55e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HFFKCMKK_00569	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFFKCMKK_00570	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HFFKCMKK_00571	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFFKCMKK_00572	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFFKCMKK_00573	1.21e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFFKCMKK_00574	7.69e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFFKCMKK_00575	2.23e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HFFKCMKK_00576	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFFKCMKK_00577	5.64e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFFKCMKK_00578	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HFFKCMKK_00579	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFFKCMKK_00581	4.86e-258	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFKCMKK_00582	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00584	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HFFKCMKK_00585	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFFKCMKK_00587	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFFKCMKK_00588	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFFKCMKK_00589	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
HFFKCMKK_00590	4.13e-192	yycI	-	-	S	-	-	-	YycH protein
HFFKCMKK_00591	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HFFKCMKK_00592	2.25e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HFFKCMKK_00593	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HFFKCMKK_00594	1.14e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFFKCMKK_00595	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFFKCMKK_00596	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00597	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00598	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFFKCMKK_00599	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFFKCMKK_00600	3.82e-157	-	-	-	S	-	-	-	repeat protein
HFFKCMKK_00601	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HFFKCMKK_00602	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFFKCMKK_00603	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HFFKCMKK_00604	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFFKCMKK_00605	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFFKCMKK_00606	1.54e-33	-	-	-	-	-	-	-	-
HFFKCMKK_00607	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFFKCMKK_00608	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFFKCMKK_00609	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFFKCMKK_00610	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HFFKCMKK_00611	1.97e-185	ylmH	-	-	S	-	-	-	S4 domain protein
HFFKCMKK_00612	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HFFKCMKK_00613	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFFKCMKK_00614	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFFKCMKK_00615	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFFKCMKK_00616	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFFKCMKK_00617	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFFKCMKK_00618	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFFKCMKK_00619	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFFKCMKK_00620	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFFKCMKK_00621	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HFFKCMKK_00622	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFFKCMKK_00623	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFFKCMKK_00624	7.76e-74	-	-	-	-	-	-	-	-
HFFKCMKK_00625	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HFFKCMKK_00626	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFFKCMKK_00627	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFFKCMKK_00628	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HFFKCMKK_00629	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HFFKCMKK_00631	5.27e-64	-	-	-	-	-	-	-	-
HFFKCMKK_00632	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFFKCMKK_00633	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HFFKCMKK_00634	7.28e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HFFKCMKK_00635	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFFKCMKK_00636	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HFFKCMKK_00637	5.28e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HFFKCMKK_00638	5.87e-65	-	-	-	-	-	-	-	-
HFFKCMKK_00639	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFFKCMKK_00640	1.13e-130	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFFKCMKK_00642	2.84e-73	-	-	-	-	-	-	-	-
HFFKCMKK_00643	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HFFKCMKK_00645	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00646	4.1e-51	-	-	-	-	-	-	-	-
HFFKCMKK_00647	6.28e-136	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HFFKCMKK_00648	7.59e-37	-	-	-	-	-	-	-	-
HFFKCMKK_00649	4.91e-80	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HFFKCMKK_00650	1.08e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFFKCMKK_00651	9.11e-123	-	-	-	-	-	-	-	-
HFFKCMKK_00652	1.37e-90	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFKCMKK_00653	2.73e-219	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFFKCMKK_00654	1.23e-194	epsB	-	-	M	-	-	-	biosynthesis protein
HFFKCMKK_00655	1.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HFFKCMKK_00656	1.56e-64	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HFFKCMKK_00657	1.19e-93	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HFFKCMKK_00658	6.65e-97	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HFFKCMKK_00659	2.57e-118	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HFFKCMKK_00660	6.6e-69	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HFFKCMKK_00662	1.22e-271	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HFFKCMKK_00663	2.68e-73	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFFKCMKK_00664	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00665	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00666	9.85e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HFFKCMKK_00667	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00668	5.28e-225	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFFKCMKK_00669	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFFKCMKK_00670	3.91e-40	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFFKCMKK_00674	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00675	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HFFKCMKK_00676	9.14e-66	-	-	-	-	-	-	-	-
HFFKCMKK_00678	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HFFKCMKK_00679	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFFKCMKK_00680	3.09e-35	-	-	-	-	-	-	-	-
HFFKCMKK_00681	1.14e-124	-	-	-	-	-	-	-	-
HFFKCMKK_00682	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFFKCMKK_00683	3.99e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFKCMKK_00684	5.18e-15	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HFFKCMKK_00685	5.36e-255	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HFFKCMKK_00686	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFFKCMKK_00687	5.91e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFKCMKK_00688	1.09e-62	-	-	-	-	-	-	-	-
HFFKCMKK_00689	1.81e-41	-	-	-	-	-	-	-	-
HFFKCMKK_00690	1.26e-60	-	-	-	-	-	-	-	-
HFFKCMKK_00691	2.26e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HFFKCMKK_00692	7.36e-179	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HFFKCMKK_00693	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFFKCMKK_00694	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFFKCMKK_00695	1.14e-170	-	-	-	L	-	-	-	Transposase
HFFKCMKK_00696	1.11e-89	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFFKCMKK_00697	3.13e-192	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFFKCMKK_00698	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFFKCMKK_00699	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFFKCMKK_00700	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HFFKCMKK_00701	4.16e-180	-	-	-	S	-	-	-	Membrane
HFFKCMKK_00702	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HFFKCMKK_00703	9.79e-29	-	-	-	-	-	-	-	-
HFFKCMKK_00704	4.1e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFFKCMKK_00705	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFFKCMKK_00706	3.61e-61	-	-	-	-	-	-	-	-
HFFKCMKK_00707	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HFFKCMKK_00708	2.94e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HFFKCMKK_00709	2.95e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
HFFKCMKK_00710	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFKCMKK_00711	0.0	potE	-	-	E	-	-	-	Amino Acid
HFFKCMKK_00712	7.99e-293	-	-	-	V	-	-	-	MatE
HFFKCMKK_00713	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFFKCMKK_00714	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFFKCMKK_00715	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFFKCMKK_00716	9.06e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFFKCMKK_00717	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFKCMKK_00718	2.36e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFKCMKK_00719	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFFKCMKK_00720	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFFKCMKK_00721	6.92e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
HFFKCMKK_00722	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HFFKCMKK_00723	7.09e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFFKCMKK_00724	1.14e-170	-	-	-	L	-	-	-	Transposase
HFFKCMKK_00725	3.66e-286	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HFFKCMKK_00727	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFFKCMKK_00728	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFFKCMKK_00729	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HFFKCMKK_00730	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
HFFKCMKK_00731	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
HFFKCMKK_00732	9.11e-114	-	-	-	C	-	-	-	Oxidoreductase
HFFKCMKK_00735	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HFFKCMKK_00736	4.89e-19	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFFKCMKK_00737	2.8e-173	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFFKCMKK_00740	5.92e-150	-	-	-	-	-	-	-	-
HFFKCMKK_00741	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_00742	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HFFKCMKK_00743	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFFKCMKK_00744	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HFFKCMKK_00745	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFFKCMKK_00746	6.42e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFFKCMKK_00747	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HFFKCMKK_00748	5.75e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFFKCMKK_00750	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HFFKCMKK_00751	6.41e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HFFKCMKK_00752	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HFFKCMKK_00753	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFFKCMKK_00754	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFKCMKK_00755	2.47e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFFKCMKK_00756	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFKCMKK_00757	5.84e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00758	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFFKCMKK_00759	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HFFKCMKK_00760	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFFKCMKK_00761	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HFFKCMKK_00762	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HFFKCMKK_00763	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFFKCMKK_00764	5.12e-266	yacL	-	-	S	-	-	-	domain protein
HFFKCMKK_00765	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFFKCMKK_00766	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFFKCMKK_00767	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFFKCMKK_00768	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFFKCMKK_00769	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFFKCMKK_00770	4.47e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFFKCMKK_00771	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFFKCMKK_00772	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFFKCMKK_00773	4.39e-287	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HFFKCMKK_00775	1.44e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HFFKCMKK_00776	1.79e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFFKCMKK_00777	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFFKCMKK_00778	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFFKCMKK_00779	2.91e-65	-	-	-	-	-	-	-	-
HFFKCMKK_00781	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFFKCMKK_00782	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HFFKCMKK_00783	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HFFKCMKK_00784	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HFFKCMKK_00785	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HFFKCMKK_00786	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFFKCMKK_00787	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFFKCMKK_00788	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HFFKCMKK_00789	1.13e-259	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HFFKCMKK_00790	6.11e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HFFKCMKK_00791	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFFKCMKK_00792	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HFFKCMKK_00793	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFFKCMKK_00794	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HFFKCMKK_00795	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HFFKCMKK_00796	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HFFKCMKK_00797	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFFKCMKK_00798	7.97e-292	-	-	-	-	-	-	-	-
HFFKCMKK_00799	6.71e-102	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFKCMKK_00800	2.74e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HFFKCMKK_00801	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFFKCMKK_00802	2.14e-154	-	-	-	GM	-	-	-	NmrA-like family
HFFKCMKK_00803	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HFFKCMKK_00804	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
HFFKCMKK_00805	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HFFKCMKK_00806	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
HFFKCMKK_00807	4.77e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HFFKCMKK_00809	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFFKCMKK_00810	1.82e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
HFFKCMKK_00811	6.2e-271	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HFFKCMKK_00812	8.57e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HFFKCMKK_00814	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00815	1.99e-204	-	-	-	J	-	-	-	Methyltransferase
HFFKCMKK_00816	6.02e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HFFKCMKK_00817	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_00818	2.48e-178	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_00819	1.64e-135	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00820	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFFKCMKK_00821	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HFFKCMKK_00822	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFFKCMKK_00823	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HFFKCMKK_00824	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HFFKCMKK_00825	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HFFKCMKK_00826	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFFKCMKK_00827	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFFKCMKK_00828	2.99e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFFKCMKK_00829	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFFKCMKK_00830	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HFFKCMKK_00831	1.38e-37	-	-	-	-	-	-	-	-
HFFKCMKK_00832	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFFKCMKK_00833	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
HFFKCMKK_00834	1.35e-182	-	-	-	G	-	-	-	MucBP domain
HFFKCMKK_00835	2.26e-145	-	-	-	-	-	-	-	-
HFFKCMKK_00836	9.75e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00837	2.41e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HFFKCMKK_00838	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFFKCMKK_00839	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HFFKCMKK_00840	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFFKCMKK_00841	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
HFFKCMKK_00842	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HFFKCMKK_00843	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HFFKCMKK_00844	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFFKCMKK_00845	1.51e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_00846	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFFKCMKK_00847	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HFFKCMKK_00848	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFFKCMKK_00849	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HFFKCMKK_00850	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HFFKCMKK_00851	1.23e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFFKCMKK_00852	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFFKCMKK_00853	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFFKCMKK_00854	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFFKCMKK_00855	2.82e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HFFKCMKK_00856	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HFFKCMKK_00857	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFFKCMKK_00858	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFFKCMKK_00859	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFFKCMKK_00860	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFFKCMKK_00861	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFFKCMKK_00862	1.08e-164	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_00863	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_00864	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFKCMKK_00865	2.44e-20	-	-	-	-	-	-	-	-
HFFKCMKK_00866	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFFKCMKK_00867	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFFKCMKK_00868	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFFKCMKK_00869	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFKCMKK_00870	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFFKCMKK_00871	1.46e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFFKCMKK_00872	1.79e-121	-	-	-	-	-	-	-	-
HFFKCMKK_00873	6.03e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFKCMKK_00874	3.75e-06	-	-	-	L	-	-	-	GIY-YIG catalytic domain
HFFKCMKK_00875	1.48e-06	-	-	-	S	-	-	-	Helix-turn-helix domain
HFFKCMKK_00879	1.59e-50	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
HFFKCMKK_00880	1.78e-108	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HFFKCMKK_00883	1.23e-36	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
HFFKCMKK_00884	1.16e-28	terS	-	-	L	-	-	-	Phage terminase, small subunit
HFFKCMKK_00885	3.9e-253	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HFFKCMKK_00886	7.25e-177	-	-	-	S	-	-	-	Phage portal protein
HFFKCMKK_00887	8.21e-317	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HFFKCMKK_00888	2.49e-25	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFFKCMKK_00891	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFFKCMKK_00892	6.77e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HFFKCMKK_00893	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFFKCMKK_00894	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HFFKCMKK_00895	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HFFKCMKK_00896	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HFFKCMKK_00897	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFFKCMKK_00898	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HFFKCMKK_00899	1.02e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFKCMKK_00900	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFFKCMKK_00901	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFFKCMKK_00902	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFFKCMKK_00903	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFFKCMKK_00904	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFFKCMKK_00905	1.18e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFFKCMKK_00906	5.46e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFFKCMKK_00907	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFFKCMKK_00908	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFFKCMKK_00909	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFFKCMKK_00910	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFFKCMKK_00911	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HFFKCMKK_00912	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HFFKCMKK_00913	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFFKCMKK_00914	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFFKCMKK_00915	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFFKCMKK_00916	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFFKCMKK_00917	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFFKCMKK_00918	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFFKCMKK_00919	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HFFKCMKK_00920	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HFFKCMKK_00921	3.68e-152	dltr	-	-	K	-	-	-	response regulator
HFFKCMKK_00922	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
HFFKCMKK_00923	2.33e-264	-	-	-	P	-	-	-	Voltage gated chloride channel
HFFKCMKK_00924	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HFFKCMKK_00925	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HFFKCMKK_00926	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
HFFKCMKK_00927	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HFFKCMKK_00928	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HFFKCMKK_00929	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HFFKCMKK_00930	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HFFKCMKK_00931	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFFKCMKK_00932	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFFKCMKK_00933	1.98e-118	-	-	-	-	-	-	-	-
HFFKCMKK_00934	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFFKCMKK_00936	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HFFKCMKK_00937	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HFFKCMKK_00938	4.94e-94	-	-	-	-	-	-	-	-
HFFKCMKK_00939	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFKCMKK_00940	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFFKCMKK_00941	0.0	-	-	-	M	-	-	-	domain protein
HFFKCMKK_00942	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFFKCMKK_00943	4.82e-238	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFFKCMKK_00944	7.01e-60	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFFKCMKK_00945	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFFKCMKK_00946	5.49e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFFKCMKK_00947	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HFFKCMKK_00948	3.01e-229	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFFKCMKK_00949	1.01e-63	-	-	-	K	-	-	-	LysR substrate binding domain
HFFKCMKK_00950	5.5e-235	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFFKCMKK_00951	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFFKCMKK_00953	1.87e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HFFKCMKK_00954	4.26e-274	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HFFKCMKK_00955	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFFKCMKK_00956	1.14e-170	-	-	-	L	-	-	-	Transposase
HFFKCMKK_00957	4.45e-70	-	-	-	M	-	-	-	Peptidase_C39 like family
HFFKCMKK_00958	6.57e-129	-	-	-	S	-	-	-	Peptidase, M23
HFFKCMKK_00959	4.63e-243	isp	-	-	L	-	-	-	Transposase
HFFKCMKK_00960	4.99e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFKCMKK_00961	5.79e-306	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HFFKCMKK_00962	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HFFKCMKK_00963	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFFKCMKK_00964	5.26e-203	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HFFKCMKK_00965	3.31e-119	-	-	-	M	-	-	-	LysM domain protein
HFFKCMKK_00966	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HFFKCMKK_00967	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
HFFKCMKK_00968	4.89e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFFKCMKK_00969	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFFKCMKK_00970	1.88e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HFFKCMKK_00971	2.05e-193	yeaE	-	-	S	-	-	-	Aldo keto
HFFKCMKK_00972	3.66e-98	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFFKCMKK_00973	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HFFKCMKK_00974	2.27e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFFKCMKK_00975	2.91e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HFFKCMKK_00976	7.03e-33	-	-	-	-	-	-	-	-
HFFKCMKK_00977	2.85e-134	-	-	-	V	-	-	-	VanZ like family
HFFKCMKK_00978	1.11e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFFKCMKK_00979	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HFFKCMKK_00980	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_00981	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HFFKCMKK_00982	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFFKCMKK_00983	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFFKCMKK_00984	1.45e-55	-	-	-	-	-	-	-	-
HFFKCMKK_00985	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFFKCMKK_00986	3.96e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFFKCMKK_00987	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HFFKCMKK_00988	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFKCMKK_00989	3.17e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFFKCMKK_00990	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HFFKCMKK_00991	3.08e-146	-	-	-	-	-	-	-	-
HFFKCMKK_00992	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HFFKCMKK_00993	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFFKCMKK_00994	1.52e-43	-	-	-	-	-	-	-	-
HFFKCMKK_00995	4.68e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFKCMKK_00996	9.17e-59	-	-	-	-	-	-	-	-
HFFKCMKK_00998	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFFKCMKK_00999	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HFFKCMKK_01000	3.36e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HFFKCMKK_01001	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFFKCMKK_01002	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HFFKCMKK_01003	9.39e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HFFKCMKK_01004	9.3e-61	-	-	-	-	-	-	-	-
HFFKCMKK_01005	3e-54	-	-	-	-	-	-	-	-
HFFKCMKK_01007	1.35e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFFKCMKK_01008	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFFKCMKK_01009	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFFKCMKK_01010	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFFKCMKK_01011	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFFKCMKK_01012	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HFFKCMKK_01013	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFFKCMKK_01014	9.31e-177	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFFKCMKK_01016	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HFFKCMKK_01017	7.73e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_01018	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFFKCMKK_01019	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFFKCMKK_01020	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
HFFKCMKK_01021	3.53e-76	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HFFKCMKK_01022	1.8e-308	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HFFKCMKK_01023	6.79e-183	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFKCMKK_01024	7.52e-101	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFKCMKK_01025	2.32e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HFFKCMKK_01026	1.21e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HFFKCMKK_01027	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
HFFKCMKK_01028	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HFFKCMKK_01029	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFFKCMKK_01030	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HFFKCMKK_01031	8.55e-46	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HFFKCMKK_01032	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFFKCMKK_01033	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFFKCMKK_01034	5.63e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HFFKCMKK_01035	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFFKCMKK_01036	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFFKCMKK_01037	5.91e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFFKCMKK_01038	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFFKCMKK_01039	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HFFKCMKK_01040	1.59e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFFKCMKK_01041	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFFKCMKK_01042	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFFKCMKK_01043	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFFKCMKK_01044	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HFFKCMKK_01045	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HFFKCMKK_01046	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HFFKCMKK_01047	2.43e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFFKCMKK_01048	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HFFKCMKK_01049	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFFKCMKK_01050	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HFFKCMKK_01051	9.69e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFFKCMKK_01052	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HFFKCMKK_01053	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HFFKCMKK_01054	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HFFKCMKK_01055	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFFKCMKK_01056	3.39e-47	isp	-	-	L	-	-	-	Transposase
HFFKCMKK_01064	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_01065	1.08e-164	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_01071	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HFFKCMKK_01072	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HFFKCMKK_01074	2.79e-153	-	-	-	I	-	-	-	phosphatase
HFFKCMKK_01075	5.02e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFFKCMKK_01076	2.09e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFFKCMKK_01077	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFFKCMKK_01078	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HFFKCMKK_01079	1.35e-210	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HFFKCMKK_01080	7.03e-150	-	-	-	S	-	-	-	membrane
HFFKCMKK_01081	7.81e-141	-	-	-	S	-	-	-	VIT family
HFFKCMKK_01082	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFFKCMKK_01083	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_01084	4.49e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFFKCMKK_01085	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFKCMKK_01086	2.46e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFFKCMKK_01087	7.14e-276	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFFKCMKK_01088	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFFKCMKK_01089	8.46e-77	-	-	-	-	-	-	-	-
HFFKCMKK_01090	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HFFKCMKK_01091	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HFFKCMKK_01092	1.91e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HFFKCMKK_01093	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFFKCMKK_01095	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFFKCMKK_01096	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HFFKCMKK_01097	1.93e-241	-	-	-	I	-	-	-	Alpha beta
HFFKCMKK_01098	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_01099	5.69e-154	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HFFKCMKK_01100	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFFKCMKK_01101	7.21e-205	-	-	-	K	-	-	-	LysR family
HFFKCMKK_01102	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFFKCMKK_01103	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFFKCMKK_01104	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFFKCMKK_01105	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HFFKCMKK_01106	5.46e-207	mleR	-	-	K	-	-	-	LysR family
HFFKCMKK_01107	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFFKCMKK_01108	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HFFKCMKK_01109	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HFFKCMKK_01110	6.08e-213	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFFKCMKK_01111	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HFFKCMKK_01112	1.36e-35	-	-	-	-	-	-	-	-
HFFKCMKK_01113	3.67e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFFKCMKK_01114	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFKCMKK_01115	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_01116	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_01117	1.69e-166	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HFFKCMKK_01118	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HFFKCMKK_01119	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HFFKCMKK_01120	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HFFKCMKK_01121	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFFKCMKK_01122	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFKCMKK_01123	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFKCMKK_01124	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFKCMKK_01125	6.39e-261	-	-	-	-	-	-	-	-
HFFKCMKK_01126	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HFFKCMKK_01127	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFFKCMKK_01128	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFFKCMKK_01129	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFFKCMKK_01130	5.8e-149	-	-	-	I	-	-	-	Acid phosphatase homologues
HFFKCMKK_01131	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HFFKCMKK_01132	6.12e-296	-	-	-	P	-	-	-	Chloride transporter, ClC family
HFFKCMKK_01133	2.71e-151	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFFKCMKK_01134	3e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFFKCMKK_01135	2.03e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFFKCMKK_01136	6.11e-68	-	-	-	-	-	-	-	-
HFFKCMKK_01137	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HFFKCMKK_01139	2.03e-307	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HFFKCMKK_01140	8.61e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
HFFKCMKK_01141	2.73e-50	-	-	-	-	-	-	-	-
HFFKCMKK_01142	1.14e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HFFKCMKK_01143	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HFFKCMKK_01144	4.52e-93	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFFKCMKK_01145	9.5e-190	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFFKCMKK_01146	3.97e-232	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFFKCMKK_01148	6.13e-133	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HFFKCMKK_01149	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HFFKCMKK_01150	8.69e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFKCMKK_01152	1.09e-226	ydhF	-	-	S	-	-	-	Aldo keto reductase
HFFKCMKK_01153	4.51e-101	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HFFKCMKK_01154	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HFFKCMKK_01156	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HFFKCMKK_01157	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HFFKCMKK_01158	7.41e-163	-	-	-	-	-	-	-	-
HFFKCMKK_01159	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HFFKCMKK_01160	3.71e-235	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HFFKCMKK_01161	4.55e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFFKCMKK_01162	1.03e-213	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HFFKCMKK_01163	8.45e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HFFKCMKK_01164	1.09e-227	-	-	-	-	-	-	-	-
HFFKCMKK_01165	1.02e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HFFKCMKK_01167	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HFFKCMKK_01168	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFFKCMKK_01169	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HFFKCMKK_01170	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFFKCMKK_01171	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFFKCMKK_01172	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HFFKCMKK_01173	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFFKCMKK_01174	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFFKCMKK_01175	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFFKCMKK_01176	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HFFKCMKK_01177	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFFKCMKK_01178	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFFKCMKK_01179	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFFKCMKK_01180	1.6e-100	-	-	-	-	-	-	-	-
HFFKCMKK_01181	1.82e-187	yidA	-	-	S	-	-	-	hydrolase
HFFKCMKK_01182	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HFFKCMKK_01183	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HFFKCMKK_01184	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HFFKCMKK_01185	1.06e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFFKCMKK_01186	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFFKCMKK_01187	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HFFKCMKK_01188	2.5e-171	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HFFKCMKK_01189	8.12e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFFKCMKK_01190	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFFKCMKK_01191	2.03e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HFFKCMKK_01192	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFFKCMKK_01193	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HFFKCMKK_01194	1.05e-193	-	-	-	-	-	-	-	-
HFFKCMKK_01195	6.56e-54	-	-	-	M	-	-	-	Glycosyl transferase
HFFKCMKK_01196	6.21e-231	-	-	-	M	-	-	-	Glycosyl transferase
HFFKCMKK_01197	1.29e-279	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HFFKCMKK_01198	7.72e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HFFKCMKK_01199	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HFFKCMKK_01200	3.91e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HFFKCMKK_01201	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HFFKCMKK_01202	2.66e-114	-	-	-	Q	-	-	-	Methyltransferase
HFFKCMKK_01203	1.48e-290	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFFKCMKK_01204	4.53e-103	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HFFKCMKK_01205	7.95e-87	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HFFKCMKK_01206	6.24e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFFKCMKK_01207	1.83e-124	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HFFKCMKK_01208	6.93e-296	-	-	-	G	ko:K03832	-	ko00000,ko02000	Belongs to the glycosyl hydrolase family 6
HFFKCMKK_01209	1.18e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HFFKCMKK_01210	3.04e-173	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFKCMKK_01211	1.97e-69	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HFFKCMKK_01212	5.91e-105	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HFFKCMKK_01213	1.86e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HFFKCMKK_01214	3.85e-72	-	-	-	-	-	-	-	-
HFFKCMKK_01215	1.08e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_01216	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFFKCMKK_01217	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFFKCMKK_01218	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFFKCMKK_01219	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFFKCMKK_01220	5.93e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFFKCMKK_01221	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFFKCMKK_01222	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFFKCMKK_01223	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFFKCMKK_01224	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFFKCMKK_01225	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HFFKCMKK_01226	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HFFKCMKK_01227	1.13e-104	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HFFKCMKK_01228	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFFKCMKK_01229	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFFKCMKK_01230	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HFFKCMKK_01231	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFFKCMKK_01232	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFFKCMKK_01233	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HFFKCMKK_01234	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFFKCMKK_01235	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFFKCMKK_01236	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFFKCMKK_01237	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFFKCMKK_01238	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HFFKCMKK_01239	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFFKCMKK_01240	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HFFKCMKK_01241	1.65e-206	-	-	-	S	-	-	-	reductase
HFFKCMKK_01243	0.0	-	-	-	S	-	-	-	amidohydrolase
HFFKCMKK_01244	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
HFFKCMKK_01245	6.14e-106	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HFFKCMKK_01246	4.53e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HFFKCMKK_01247	6.38e-151	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HFFKCMKK_01249	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HFFKCMKK_01250	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HFFKCMKK_01251	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HFFKCMKK_01252	1.02e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFFKCMKK_01253	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
HFFKCMKK_01254	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_01255	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
HFFKCMKK_01261	0.000773	-	-	-	S	-	-	-	YopX protein
HFFKCMKK_01273	2.57e-35	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFFKCMKK_01283	8.2e-92	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFKCMKK_01285	3.42e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFFKCMKK_01286	1.28e-18	-	-	-	-	-	-	-	-
HFFKCMKK_01287	8.1e-281	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFKCMKK_01288	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFFKCMKK_01289	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFFKCMKK_01290	7.13e-227	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFFKCMKK_01291	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HFFKCMKK_01292	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HFFKCMKK_01293	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HFFKCMKK_01294	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HFFKCMKK_01295	1.38e-59	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HFFKCMKK_01296	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HFFKCMKK_01297	2.68e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFFKCMKK_01298	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFFKCMKK_01299	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFFKCMKK_01300	0.0	-	-	-	S	-	-	-	membrane
HFFKCMKK_01301	1.33e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HFFKCMKK_01302	3.11e-63	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HFFKCMKK_01303	1.2e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFFKCMKK_01304	3.66e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFFKCMKK_01305	1.11e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFFKCMKK_01306	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFFKCMKK_01307	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFFKCMKK_01308	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFFKCMKK_01309	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFFKCMKK_01310	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFFKCMKK_01311	1.18e-176	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFFKCMKK_01312	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFKCMKK_01313	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFFKCMKK_01314	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HFFKCMKK_01315	6.63e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HFFKCMKK_01316	7.55e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFFKCMKK_01317	5.28e-76	-	-	-	-	-	-	-	-
HFFKCMKK_01319	3.3e-265	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFFKCMKK_01320	4.37e-39	-	-	-	-	-	-	-	-
HFFKCMKK_01321	4.84e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HFFKCMKK_01322	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFFKCMKK_01323	6.08e-102	-	-	-	-	-	-	-	-
HFFKCMKK_01324	3.58e-253	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HFFKCMKK_01325	2.31e-159	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFFKCMKK_01326	2.77e-19	-	-	-	L	-	-	-	Integrase core domain
HFFKCMKK_01327	6.97e-244	-	-	-	L	-	-	-	Integrase core domain
HFFKCMKK_01328	2.98e-163	-	-	-	O	-	-	-	Bacterial dnaA protein
HFFKCMKK_01329	1.27e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HFFKCMKK_01332	2.06e-247	-	-	-	L	-	-	-	Integrase core domain
HFFKCMKK_01354	8.74e-300	-	-	-	L	-	-	-	Integrase core domain
HFFKCMKK_01355	9.96e-31	-	-	-	L	-	-	-	helicase activity
HFFKCMKK_01356	1.69e-46	-	-	-	L	-	-	-	helicase activity
HFFKCMKK_01358	1.03e-72	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFFKCMKK_01360	2.66e-275	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFFKCMKK_01361	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFFKCMKK_01362	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFFKCMKK_01363	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFFKCMKK_01364	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFFKCMKK_01365	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFFKCMKK_01366	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFFKCMKK_01367	1.02e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HFFKCMKK_01368	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFFKCMKK_01369	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFFKCMKK_01370	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFFKCMKK_01371	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFFKCMKK_01372	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFFKCMKK_01373	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
HFFKCMKK_01374	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFFKCMKK_01375	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFFKCMKK_01376	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFFKCMKK_01377	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFFKCMKK_01378	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFFKCMKK_01379	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HFFKCMKK_01380	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HFFKCMKK_01381	9.06e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFFKCMKK_01382	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HFFKCMKK_01383	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFFKCMKK_01384	1.84e-75	-	-	-	-	-	-	-	-
HFFKCMKK_01385	4.4e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFFKCMKK_01386	3.28e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFFKCMKK_01387	1.15e-178	-	-	-	-	-	-	-	-
HFFKCMKK_01388	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HFFKCMKK_01389	2.17e-99	-	-	-	S	-	-	-	Fic/DOC family
HFFKCMKK_01390	3.95e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFFKCMKK_01391	8.89e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFFKCMKK_01392	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HFFKCMKK_01393	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HFFKCMKK_01394	1.01e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HFFKCMKK_01395	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HFFKCMKK_01396	1.76e-143	-	-	-	F	-	-	-	NUDIX domain
HFFKCMKK_01397	1.5e-289	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFFKCMKK_01398	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
HFFKCMKK_01399	1.65e-83	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
HFFKCMKK_01400	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
HFFKCMKK_01401	1.54e-96	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_01402	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFFKCMKK_01403	1.26e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HFFKCMKK_01404	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFFKCMKK_01405	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFFKCMKK_01406	4.8e-72	-	-	-	-	-	-	-	-
HFFKCMKK_01407	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFFKCMKK_01408	1.28e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HFFKCMKK_01409	7.92e-76	-	-	-	-	-	-	-	-
HFFKCMKK_01410	2.13e-189	yvgN	-	-	C	-	-	-	Aldo keto reductase
HFFKCMKK_01411	7.32e-179	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HFFKCMKK_01412	1.55e-104	-	-	-	C	-	-	-	Flavodoxin
HFFKCMKK_01413	2.58e-100	-	-	-	S	-	-	-	Cupin domain
HFFKCMKK_01414	3.87e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
HFFKCMKK_01415	3.94e-307	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HFFKCMKK_01416	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HFFKCMKK_01417	1.84e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HFFKCMKK_01418	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HFFKCMKK_01419	2.37e-184	-	-	-	S	-	-	-	DUF218 domain
HFFKCMKK_01420	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFFKCMKK_01421	7.52e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFFKCMKK_01422	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFFKCMKK_01423	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HFFKCMKK_01424	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFFKCMKK_01425	1.27e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HFFKCMKK_01426	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFFKCMKK_01428	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HFFKCMKK_01429	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HFFKCMKK_01430	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFKCMKK_01431	6.74e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFFKCMKK_01432	2.05e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HFFKCMKK_01433	1.66e-303	-	-	-	T	-	-	-	GHKL domain
HFFKCMKK_01434	7.62e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFFKCMKK_01435	3.51e-89	-	-	-	P	-	-	-	FAD-binding domain
HFFKCMKK_01436	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HFFKCMKK_01437	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFFKCMKK_01438	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFFKCMKK_01439	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFFKCMKK_01440	1.94e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HFFKCMKK_01441	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
HFFKCMKK_01442	2.15e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_01443	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HFFKCMKK_01444	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
HFFKCMKK_01445	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
HFFKCMKK_01446	2.49e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HFFKCMKK_01447	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
HFFKCMKK_01448	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
HFFKCMKK_01449	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HFFKCMKK_01450	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HFFKCMKK_01451	5.61e-75	-	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_01452	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_01453	6.58e-36	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFFKCMKK_01454	1.14e-149	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFFKCMKK_01455	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HFFKCMKK_01456	1.47e-104	-	-	-	S	-	-	-	membrane
HFFKCMKK_01457	3.43e-110	-	-	-	S	-	-	-	membrane
HFFKCMKK_01458	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
HFFKCMKK_01459	1.74e-85	-	-	-	-	-	-	-	-
HFFKCMKK_01460	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
HFFKCMKK_01461	5.28e-181	-	-	-	T	-	-	-	EAL domain
HFFKCMKK_01462	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HFFKCMKK_01463	7.01e-109	-	-	-	-	-	-	-	-
HFFKCMKK_01466	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HFFKCMKK_01467	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFFKCMKK_01468	3.28e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFFKCMKK_01469	1.98e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFFKCMKK_01470	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFFKCMKK_01471	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HFFKCMKK_01472	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFFKCMKK_01473	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFFKCMKK_01474	1.13e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFFKCMKK_01483	6.61e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HFFKCMKK_01484	9.59e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HFFKCMKK_01485	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFFKCMKK_01486	4.22e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFFKCMKK_01487	1.01e-28	-	-	-	-	-	-	-	-
HFFKCMKK_01488	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HFFKCMKK_01489	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFFKCMKK_01490	2.54e-60	yrvD	-	-	S	-	-	-	Pfam:DUF1049
HFFKCMKK_01492	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HFFKCMKK_01493	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFKCMKK_01494	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFFKCMKK_01495	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HFFKCMKK_01496	3.05e-69	-	-	-	-	-	-	-	-
HFFKCMKK_01497	1.2e-238	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFKCMKK_01498	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFFKCMKK_01499	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HFFKCMKK_01500	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFFKCMKK_01501	7.57e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFFKCMKK_01502	2.17e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HFFKCMKK_01503	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFFKCMKK_01504	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFFKCMKK_01505	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFFKCMKK_01506	4.94e-285	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFFKCMKK_01507	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFFKCMKK_01508	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFFKCMKK_01509	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFFKCMKK_01510	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFFKCMKK_01511	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFFKCMKK_01512	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HFFKCMKK_01513	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFFKCMKK_01514	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFFKCMKK_01515	1.91e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFFKCMKK_01516	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFFKCMKK_01517	3.75e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFFKCMKK_01518	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFFKCMKK_01519	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFFKCMKK_01520	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFFKCMKK_01521	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFFKCMKK_01522	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFFKCMKK_01523	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFFKCMKK_01524	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFFKCMKK_01525	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFFKCMKK_01526	9e-72	-	-	-	-	-	-	-	-
HFFKCMKK_01527	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFFKCMKK_01528	1.25e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFFKCMKK_01529	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HFFKCMKK_01530	8.12e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFFKCMKK_01531	3.31e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFFKCMKK_01532	1.27e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFFKCMKK_01533	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFFKCMKK_01534	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFFKCMKK_01535	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HFFKCMKK_01536	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HFFKCMKK_01537	1.06e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFFKCMKK_01538	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFFKCMKK_01539	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFFKCMKK_01540	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HFFKCMKK_01541	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFFKCMKK_01542	7.77e-144	-	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_01545	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
HFFKCMKK_01546	1.47e-223	-	-	-	-	-	-	-	-
HFFKCMKK_01547	4.87e-203	-	-	-	-	-	-	-	-
HFFKCMKK_01548	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFFKCMKK_01549	1.64e-117	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFFKCMKK_01550	7.28e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFFKCMKK_01551	8.37e-14	-	-	-	T	-	-	-	SpoVT / AbrB like domain
HFFKCMKK_01552	2.61e-235	-	-	-	M	-	-	-	lysozyme activity
HFFKCMKK_01556	0.0	-	-	-	LM	-	-	-	gp58-like protein
HFFKCMKK_01557	1.1e-69	-	-	-	-	-	-	-	-
HFFKCMKK_01558	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HFFKCMKK_01559	9.13e-44	-	-	-	-	-	-	-	-
HFFKCMKK_01560	3.28e-75	-	-	-	-	-	-	-	-
HFFKCMKK_01561	3.23e-94	-	-	-	S	-	-	-	Phage tail tube protein, TTP
HFFKCMKK_01562	4.15e-58	-	-	-	-	-	-	-	-
HFFKCMKK_01563	7.4e-101	-	-	-	-	-	-	-	-
HFFKCMKK_01564	9.81e-77	-	-	-	-	-	-	-	-
HFFKCMKK_01565	2.82e-47	-	-	-	-	-	-	-	-
HFFKCMKK_01566	8.56e-215	-	-	-	S	-	-	-	Phage major capsid protein E
HFFKCMKK_01567	1.8e-72	-	-	-	-	-	-	-	-
HFFKCMKK_01568	2.62e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HFFKCMKK_01569	7.62e-192	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFFKCMKK_01570	5.97e-274	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HFFKCMKK_01571	5.18e-275	-	-	-	S	-	-	-	Terminase-like family
HFFKCMKK_01572	3.82e-163	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HFFKCMKK_01575	3.71e-87	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
HFFKCMKK_01576	1.15e-09	-	-	-	-	-	-	-	-
HFFKCMKK_01584	4.07e-80	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HFFKCMKK_01585	2.01e-22	-	-	-	-	-	-	-	-
HFFKCMKK_01591	5.91e-65	-	-	-	S	-	-	-	ORF6C domain
HFFKCMKK_01594	2.05e-72	-	-	-	-	-	-	-	-
HFFKCMKK_01595	2.27e-171	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFFKCMKK_01596	5.48e-71	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HFFKCMKK_01597	3.52e-101	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HFFKCMKK_01608	1.14e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFFKCMKK_01611	6.41e-26	-	-	-	-	-	-	-	-
HFFKCMKK_01612	8.3e-10	-	-	-	-	-	-	-	-
HFFKCMKK_01616	7.96e-35	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFKCMKK_01617	1.66e-92	-	-	-	S	-	-	-	IrrE N-terminal-like domain
HFFKCMKK_01618	1.55e-10	-	-	-	-	-	-	-	-
HFFKCMKK_01622	3.42e-52	-	-	-	-	-	-	-	-
HFFKCMKK_01623	7.59e-64	-	-	-	-	-	-	-	-
HFFKCMKK_01624	3.91e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFFKCMKK_01625	3.43e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFFKCMKK_01626	6.45e-49	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFFKCMKK_01627	4.26e-198	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFFKCMKK_01628	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFFKCMKK_01629	5.1e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HFFKCMKK_01630	4.11e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFFKCMKK_01631	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HFFKCMKK_01632	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFFKCMKK_01633	2.11e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HFFKCMKK_01634	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFFKCMKK_01635	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFFKCMKK_01636	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFFKCMKK_01637	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFFKCMKK_01638	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFFKCMKK_01639	1.71e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFFKCMKK_01640	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFFKCMKK_01641	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFFKCMKK_01642	1.25e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFFKCMKK_01643	1.58e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFFKCMKK_01644	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFFKCMKK_01645	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFFKCMKK_01646	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFFKCMKK_01647	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HFFKCMKK_01648	2.74e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFFKCMKK_01649	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFFKCMKK_01650	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFFKCMKK_01651	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFFKCMKK_01652	1.43e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFFKCMKK_01653	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFFKCMKK_01654	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
HFFKCMKK_01655	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFFKCMKK_01656	2.15e-83	-	-	-	M	-	-	-	Lysin motif
HFFKCMKK_01657	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFFKCMKK_01658	1.73e-273	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFFKCMKK_01659	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFFKCMKK_01660	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFFKCMKK_01661	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HFFKCMKK_01662	4.94e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFFKCMKK_01663	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_01664	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFFKCMKK_01665	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFFKCMKK_01666	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HFFKCMKK_01667	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HFFKCMKK_01668	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HFFKCMKK_01669	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HFFKCMKK_01670	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFFKCMKK_01671	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFFKCMKK_01672	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFFKCMKK_01673	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HFFKCMKK_01674	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFFKCMKK_01675	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFFKCMKK_01676	1.1e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFFKCMKK_01677	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFFKCMKK_01678	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFFKCMKK_01679	1.98e-110	-	-	-	F	-	-	-	NUDIX domain
HFFKCMKK_01680	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HFFKCMKK_01682	4.31e-180	-	-	-	L	-	-	-	Bacterial dnaA protein
HFFKCMKK_01683	8.63e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFFKCMKK_01684	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HFFKCMKK_01685	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HFFKCMKK_01686	5.11e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFFKCMKK_01687	1.76e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HFFKCMKK_01693	0.000222	ydiL	-	-	S	ko:K07052	-	ko00000	protease
HFFKCMKK_01696	1.79e-64	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFFKCMKK_01698	2.58e-239	-	-	-	U	-	-	-	type IV secretory pathway VirB4
HFFKCMKK_01699	4.26e-35	-	-	-	-	-	-	-	-
HFFKCMKK_01701	1.9e-72	-	-	-	-	-	-	-	-
HFFKCMKK_01702	2.88e-277	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HFFKCMKK_01705	6.64e-99	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HFFKCMKK_01706	3.3e-105	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFFKCMKK_01707	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFFKCMKK_01708	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFFKCMKK_01709	4.08e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HFFKCMKK_01710	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
HFFKCMKK_01711	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HFFKCMKK_01712	0.0	potE	-	-	E	-	-	-	Amino Acid
HFFKCMKK_01713	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFFKCMKK_01714	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HFFKCMKK_01715	1.25e-42	-	-	-	-	-	-	-	-
HFFKCMKK_01716	2.86e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HFFKCMKK_01717	3.17e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HFFKCMKK_01718	8.95e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HFFKCMKK_01719	8.1e-153	-	-	-	M	-	-	-	Bacterial sugar transferase
HFFKCMKK_01720	6.15e-83	-	-	-	-	-	-	-	-
HFFKCMKK_01721	1.69e-43	-	-	-	M	-	-	-	biosynthesis protein
HFFKCMKK_01722	2.42e-82	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HFFKCMKK_01723	2.78e-96	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
HFFKCMKK_01724	9.41e-196	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HFFKCMKK_01725	1.96e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HFFKCMKK_01726	1.02e-289	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFFKCMKK_01727	3.18e-89	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HFFKCMKK_01728	2.16e-61	cps3I	-	-	G	-	-	-	Acyltransferase family
HFFKCMKK_01729	3.41e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFFKCMKK_01730	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HFFKCMKK_01731	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFFKCMKK_01732	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFFKCMKK_01733	5.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFFKCMKK_01734	3.21e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HFFKCMKK_01735	3.49e-48	-	-	-	-	-	-	-	-
HFFKCMKK_01736	4.33e-69	-	-	-	-	-	-	-	-
HFFKCMKK_01737	2.61e-260	-	-	-	-	-	-	-	-
HFFKCMKK_01738	1.59e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFFKCMKK_01739	8.01e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HFFKCMKK_01740	6.94e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
HFFKCMKK_01741	3.56e-160	XK27_10500	-	-	K	-	-	-	response regulator
HFFKCMKK_01742	2.4e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HFFKCMKK_01743	9.68e-172	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFFKCMKK_01744	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HFFKCMKK_01745	9.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFFKCMKK_01746	7.55e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFFKCMKK_01747	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFKCMKK_01748	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_01749	1.42e-111	ymdB	-	-	S	-	-	-	Macro domain protein
HFFKCMKK_01750	8.68e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
HFFKCMKK_01751	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFFKCMKK_01752	2.45e-63	-	-	-	-	-	-	-	-
HFFKCMKK_01753	1.47e-304	-	-	-	S	-	-	-	Putative metallopeptidase domain
HFFKCMKK_01754	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
HFFKCMKK_01755	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFFKCMKK_01756	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HFFKCMKK_01757	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFFKCMKK_01758	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HFFKCMKK_01759	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFFKCMKK_01760	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HFFKCMKK_01761	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HFFKCMKK_01762	1.05e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFFKCMKK_01763	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HFFKCMKK_01764	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFFKCMKK_01765	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFFKCMKK_01766	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFFKCMKK_01767	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFFKCMKK_01768	9.72e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFFKCMKK_01769	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFFKCMKK_01770	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFFKCMKK_01771	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFFKCMKK_01772	3.81e-292	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HFFKCMKK_01773	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HFFKCMKK_01774	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HFFKCMKK_01775	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFFKCMKK_01776	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFFKCMKK_01777	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFFKCMKK_01778	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFFKCMKK_01779	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFFKCMKK_01780	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFFKCMKK_01781	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFFKCMKK_01782	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HFFKCMKK_01783	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HFFKCMKK_01784	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HFFKCMKK_01785	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HFFKCMKK_01786	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFFKCMKK_01787	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HFFKCMKK_01788	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
HFFKCMKK_01789	2.01e-76	-	-	-	-	-	-	-	-
HFFKCMKK_01790	0.0	-	-	-	M	-	-	-	domain protein
HFFKCMKK_01791	9.23e-138	-	-	-	-	-	-	-	-
HFFKCMKK_01793	2.54e-199	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFKCMKK_01794	4.95e-92	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFFKCMKK_01796	2.13e-74	-	-	-	-	-	-	-	-
HFFKCMKK_01798	1.23e-110	-	-	-	-	-	-	-	-
HFFKCMKK_01799	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFFKCMKK_01800	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HFFKCMKK_01801	1.31e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
HFFKCMKK_01802	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HFFKCMKK_01803	3.18e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HFFKCMKK_01804	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HFFKCMKK_01805	1.31e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFFKCMKK_01806	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HFFKCMKK_01807	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HFFKCMKK_01808	2.08e-208	xylR	-	-	GK	-	-	-	ROK family
HFFKCMKK_01809	2.49e-39	-	-	-	-	-	-	-	-
HFFKCMKK_01810	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFFKCMKK_01811	6.42e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HFFKCMKK_01812	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFFKCMKK_01813	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HFFKCMKK_01814	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HFFKCMKK_01816	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
HFFKCMKK_01817	9.84e-194	-	-	-	S	-	-	-	Cof-like hydrolase
HFFKCMKK_01818	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
HFFKCMKK_01819	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HFFKCMKK_01820	5.17e-70	-	-	-	-	-	-	-	-
HFFKCMKK_01821	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFFKCMKK_01822	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFFKCMKK_01823	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HFFKCMKK_01824	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFFKCMKK_01825	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HFFKCMKK_01826	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFFKCMKK_01827	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFFKCMKK_01828	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HFFKCMKK_01829	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFFKCMKK_01830	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HFFKCMKK_01831	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFKCMKK_01832	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HFFKCMKK_01833	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HFFKCMKK_01834	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFFKCMKK_01835	9.61e-137	-	-	-	-	-	-	-	-
HFFKCMKK_01836	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFFKCMKK_01837	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFFKCMKK_01838	3.43e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HFFKCMKK_01839	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFFKCMKK_01840	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFFKCMKK_01841	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HFFKCMKK_01842	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFFKCMKK_01843	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFKCMKK_01844	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFFKCMKK_01845	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFFKCMKK_01847	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFFKCMKK_01848	1.83e-21	-	-	-	-	-	-	-	-
HFFKCMKK_01850	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFFKCMKK_01851	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFFKCMKK_01852	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFFKCMKK_01853	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFFKCMKK_01854	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFFKCMKK_01855	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFFKCMKK_01856	2.12e-19	-	-	-	-	-	-	-	-
HFFKCMKK_01857	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HFFKCMKK_01858	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFFKCMKK_01859	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HFFKCMKK_01860	5.89e-201	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HFFKCMKK_01861	4.47e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HFFKCMKK_01862	2.38e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFFKCMKK_01863	8.82e-203	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HFFKCMKK_01864	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HFFKCMKK_01865	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HFFKCMKK_01866	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFFKCMKK_01867	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFFKCMKK_01868	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFFKCMKK_01869	7.99e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFFKCMKK_01870	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HFFKCMKK_01871	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HFFKCMKK_01872	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFFKCMKK_01873	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFFKCMKK_01874	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFFKCMKK_01875	5.75e-146	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HFFKCMKK_01876	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HFFKCMKK_01877	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HFFKCMKK_01878	2.24e-301	-	-	-	EGP	-	-	-	Major Facilitator
HFFKCMKK_01879	1.24e-65	-	-	-	-	-	-	-	-
HFFKCMKK_01880	4.13e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HFFKCMKK_01881	9.83e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFFKCMKK_01882	2.57e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HFFKCMKK_01883	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HFFKCMKK_01884	6.71e-92	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFFKCMKK_01885	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFFKCMKK_01886	9.15e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HFFKCMKK_01887	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFFKCMKK_01888	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HFFKCMKK_01889	1.74e-307	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HFFKCMKK_01890	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFFKCMKK_01891	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HFFKCMKK_01892	2.07e-202	gspA	-	-	M	-	-	-	family 8
HFFKCMKK_01893	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFKCMKK_01894	7.49e-124	-	-	-	-	-	-	-	-
HFFKCMKK_01895	5.11e-208	-	-	-	S	-	-	-	EDD domain protein, DegV family
HFFKCMKK_01896	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HFFKCMKK_01897	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HFFKCMKK_01898	5.97e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HFFKCMKK_01899	6.76e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFFKCMKK_01900	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HFFKCMKK_01901	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFFKCMKK_01902	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFKCMKK_01903	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HFFKCMKK_01905	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HFFKCMKK_01906	1.61e-54	-	-	-	-	-	-	-	-
HFFKCMKK_01907	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HFFKCMKK_01908	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HFFKCMKK_01909	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HFFKCMKK_01910	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HFFKCMKK_01911	3.67e-46	-	-	-	-	-	-	-	-
HFFKCMKK_01912	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HFFKCMKK_01913	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFFKCMKK_01914	1.55e-109	-	-	-	-	-	-	-	-
HFFKCMKK_01915	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HFFKCMKK_01916	3.99e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFFKCMKK_01917	1.86e-24	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFFKCMKK_01918	2.08e-145	-	-	-	S	-	-	-	Membrane
HFFKCMKK_01919	1.98e-83	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HFFKCMKK_01920	2.69e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFFKCMKK_01921	1.77e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFFKCMKK_01923	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFFKCMKK_01924	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFFKCMKK_01925	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFFKCMKK_01926	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFFKCMKK_01927	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFFKCMKK_01928	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFFKCMKK_01929	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFFKCMKK_01930	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFFKCMKK_01931	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFFKCMKK_01932	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFFKCMKK_01933	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFFKCMKK_01934	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFFKCMKK_01935	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFFKCMKK_01936	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFFKCMKK_01937	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFFKCMKK_01938	1.06e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFFKCMKK_01939	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFFKCMKK_01940	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFFKCMKK_01941	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFFKCMKK_01942	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFFKCMKK_01943	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFFKCMKK_01944	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFFKCMKK_01945	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFFKCMKK_01946	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HFFKCMKK_01947	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFFKCMKK_01948	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFFKCMKK_01949	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFKCMKK_01950	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFFKCMKK_01951	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFKCMKK_01952	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFKCMKK_01953	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFKCMKK_01954	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFFKCMKK_01955	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFFKCMKK_01956	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFFKCMKK_01957	6.59e-144	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HFFKCMKK_01958	5.41e-25	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HFFKCMKK_01959	8.45e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HFFKCMKK_01960	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFFKCMKK_01961	2.28e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFFKCMKK_01962	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFFKCMKK_01963	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFFKCMKK_01964	1.91e-261	camS	-	-	S	-	-	-	sex pheromone
HFFKCMKK_01965	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFFKCMKK_01966	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFFKCMKK_01967	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFFKCMKK_01968	5.06e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HFFKCMKK_01969	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFFKCMKK_01973	6.65e-187	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HFFKCMKK_01974	1.02e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HFFKCMKK_01975	2.74e-265	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HFFKCMKK_01976	3.34e-60	-	-	-	-	-	-	-	-
HFFKCMKK_01977	1.42e-35	-	-	-	-	-	-	-	-
HFFKCMKK_01979	2.36e-185	-	-	-	-	-	-	-	-
HFFKCMKK_01980	3.18e-107	-	-	-	-	-	-	-	-
HFFKCMKK_01981	1.51e-112	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain