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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NIKBCBBA_00008	2.78e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIKBCBBA_00009	1.25e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIKBCBBA_00010	1.06e-149	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NIKBCBBA_00011	4.49e-144	yjbH	-	-	Q	-	-	-	Thioredoxin
NIKBCBBA_00012	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIKBCBBA_00013	9.73e-255	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NIKBCBBA_00014	9.4e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NIKBCBBA_00015	3.35e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIKBCBBA_00016	5.33e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NIKBCBBA_00017	6.14e-44	-	-	-	S	-	-	-	Transglycosylase associated protein
NIKBCBBA_00018	3.74e-09	-	-	-	S	-	-	-	CsbD-like
NIKBCBBA_00019	8.98e-228	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIKBCBBA_00020	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NIKBCBBA_00021	8.02e-119	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
NIKBCBBA_00022	1.39e-49	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NIKBCBBA_00023	7.08e-188	-	-	-	-	-	-	-	-
NIKBCBBA_00024	7.4e-30	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NIKBCBBA_00025	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NIKBCBBA_00026	7.02e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NIKBCBBA_00027	2.43e-95	-	-	-	F	-	-	-	Nudix hydrolase
NIKBCBBA_00028	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NIKBCBBA_00029	1.02e-281	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NIKBCBBA_00030	1.72e-285	-	-	-	-	-	-	-	-
NIKBCBBA_00031	9.11e-262	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIKBCBBA_00032	3.12e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIKBCBBA_00033	8.33e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIKBCBBA_00034	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NIKBCBBA_00035	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NIKBCBBA_00036	4.29e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NIKBCBBA_00037	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NIKBCBBA_00038	6.91e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NIKBCBBA_00039	0.0	yagE	-	-	E	-	-	-	amino acid
NIKBCBBA_00040	3.04e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NIKBCBBA_00041	1.14e-231	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NIKBCBBA_00042	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NIKBCBBA_00043	1.1e-177	-	-	-	IQ	-	-	-	KR domain
NIKBCBBA_00044	1.21e-170	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NIKBCBBA_00045	2.03e-125	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NIKBCBBA_00046	2.71e-316	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00047	1.18e-146	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NIKBCBBA_00048	5.35e-70	-	-	-	-	-	-	-	-
NIKBCBBA_00049	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NIKBCBBA_00050	1.05e-67	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NIKBCBBA_00051	1.91e-236	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NIKBCBBA_00052	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_00053	1.84e-202	-	-	-	-	-	-	-	-
NIKBCBBA_00054	6.5e-165	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIKBCBBA_00055	6.43e-214	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NIKBCBBA_00056	2.95e-111	-	-	-	K	-	-	-	FCD
NIKBCBBA_00057	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NIKBCBBA_00058	3.6e-266	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_00059	2.63e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NIKBCBBA_00060	1.84e-148	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NIKBCBBA_00061	3.61e-10	-	-	-	-	-	-	-	-
NIKBCBBA_00062	8.47e-82	-	-	-	-	-	-	-	-
NIKBCBBA_00063	2.76e-246	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NIKBCBBA_00064	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
NIKBCBBA_00065	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NIKBCBBA_00067	3.09e-213	-	-	-	GK	-	-	-	ROK family
NIKBCBBA_00068	1.73e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NIKBCBBA_00069	3.97e-174	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
NIKBCBBA_00070	3.76e-304	-	-	-	E	-	-	-	amino acid
NIKBCBBA_00071	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NIKBCBBA_00072	5.85e-169	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NIKBCBBA_00073	2e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIKBCBBA_00074	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIKBCBBA_00075	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NIKBCBBA_00076	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00077	2.34e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIKBCBBA_00078	4.13e-116	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
NIKBCBBA_00079	3.85e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
NIKBCBBA_00080	5.87e-234	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NIKBCBBA_00081	1.72e-153	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
NIKBCBBA_00082	6.75e-138	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
NIKBCBBA_00083	2.18e-169	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NIKBCBBA_00084	2.08e-132	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
NIKBCBBA_00085	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NIKBCBBA_00086	5.44e-230	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
NIKBCBBA_00087	3.9e-214	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NIKBCBBA_00088	6.98e-303	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NIKBCBBA_00089	4.7e-103	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
NIKBCBBA_00090	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NIKBCBBA_00091	8.38e-190	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
NIKBCBBA_00092	1.43e-151	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NIKBCBBA_00093	1.48e-69	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NIKBCBBA_00094	4.44e-171	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NIKBCBBA_00095	1.22e-158	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NIKBCBBA_00096	2.4e-185	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
NIKBCBBA_00097	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NIKBCBBA_00098	4.89e-161	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
NIKBCBBA_00099	5.86e-168	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NIKBCBBA_00100	2.94e-239	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
NIKBCBBA_00101	2.77e-172	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NIKBCBBA_00102	6.8e-123	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NIKBCBBA_00103	2.25e-138	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NIKBCBBA_00104	5.94e-262	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NIKBCBBA_00105	3.82e-157	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
NIKBCBBA_00106	1.01e-207	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NIKBCBBA_00107	2.23e-286	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NIKBCBBA_00108	3.06e-242	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
NIKBCBBA_00109	1.36e-124	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
NIKBCBBA_00110	7.99e-190	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
NIKBCBBA_00111	2.34e-97	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NIKBCBBA_00112	1.28e-93	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
NIKBCBBA_00113	2.83e-111	-	-	-	P	-	-	-	Cadmium resistance transporter
NIKBCBBA_00114	8.07e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
NIKBCBBA_00115	9.32e-181	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
NIKBCBBA_00116	1.3e-71	-	-	-	E	ko:K04031	-	ko00000	BMC
NIKBCBBA_00117	7.37e-273	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIKBCBBA_00118	4.92e-265	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
NIKBCBBA_00119	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
NIKBCBBA_00120	4.82e-103	pduO	-	-	S	-	-	-	Haem-degrading
NIKBCBBA_00121	5.76e-134	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
NIKBCBBA_00122	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
NIKBCBBA_00123	6.23e-113	-	-	-	S	-	-	-	Putative propanediol utilisation
NIKBCBBA_00124	4.86e-149	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NIKBCBBA_00125	4.11e-57	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
NIKBCBBA_00126	6.46e-92	-	-	-	CQ	-	-	-	BMC
NIKBCBBA_00127	1.05e-72	pduH	-	-	S	-	-	-	Dehydratase medium subunit
NIKBCBBA_00128	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
NIKBCBBA_00129	1.23e-103	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
NIKBCBBA_00130	3.24e-160	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
NIKBCBBA_00131	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
NIKBCBBA_00132	3.41e-170	pduB	-	-	E	-	-	-	BMC
NIKBCBBA_00133	2.72e-56	-	-	-	CQ	-	-	-	BMC
NIKBCBBA_00134	1.12e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NIKBCBBA_00135	3.36e-185	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
NIKBCBBA_00136	8.08e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NIKBCBBA_00137	7.75e-188	-	-	-	-	-	-	-	-
NIKBCBBA_00138	1.49e-190	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NIKBCBBA_00139	1.18e-239	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
NIKBCBBA_00140	5.02e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
NIKBCBBA_00141	9.54e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_00142	5.04e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NIKBCBBA_00143	6.37e-114	-	-	-	GM	-	-	-	epimerase
NIKBCBBA_00144	9.64e-190	-	-	-	V	-	-	-	(ABC) transporter
NIKBCBBA_00145	1.95e-306	yhdP	-	-	S	-	-	-	Transporter associated domain
NIKBCBBA_00146	1.1e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NIKBCBBA_00147	1.23e-95	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
NIKBCBBA_00148	1.01e-244	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NIKBCBBA_00149	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIKBCBBA_00150	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIKBCBBA_00151	5.91e-51	-	-	-	-	-	-	-	-
NIKBCBBA_00152	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NIKBCBBA_00153	1.1e-102	usp5	-	-	T	-	-	-	universal stress protein
NIKBCBBA_00154	3.28e-105	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
NIKBCBBA_00155	1.24e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIKBCBBA_00156	4.25e-124	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NIKBCBBA_00157	2.92e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NIKBCBBA_00158	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NIKBCBBA_00159	1.92e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIKBCBBA_00160	1.53e-217	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NIKBCBBA_00161	6.12e-184	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NIKBCBBA_00162	1.86e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NIKBCBBA_00163	1.21e-48	-	-	-	-	-	-	-	-
NIKBCBBA_00164	1.7e-66	-	-	-	-	-	-	-	-
NIKBCBBA_00165	5.04e-258	-	-	-	-	-	-	-	-
NIKBCBBA_00166	6.73e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIKBCBBA_00167	2.39e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NIKBCBBA_00168	4.49e-196	yvgN	-	-	S	-	-	-	Aldo keto reductase
NIKBCBBA_00169	8.39e-159	XK27_10500	-	-	K	-	-	-	response regulator
NIKBCBBA_00170	2.4e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
NIKBCBBA_00171	7.95e-171	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00172	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NIKBCBBA_00173	2.01e-198	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NIKBCBBA_00174	1.93e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
NIKBCBBA_00175	3.84e-206	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NIKBCBBA_00176	2.79e-69	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NIKBCBBA_00177	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_00178	3.56e-197	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIKBCBBA_00179	7.77e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIKBCBBA_00180	9.64e-141	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NIKBCBBA_00181	1.3e-204	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NIKBCBBA_00182	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIKBCBBA_00183	3.72e-74	-	-	-	S	-	-	-	integral membrane protein
NIKBCBBA_00184	2.63e-214	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
NIKBCBBA_00185	2.22e-87	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIKBCBBA_00187	3.33e-89	-	-	-	S	-	-	-	Acyltransferase family
NIKBCBBA_00188	2.01e-97	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
NIKBCBBA_00189	7.27e-83	-	-	-	S	-	-	-	Glycosyltransferase like family
NIKBCBBA_00190	6.29e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
NIKBCBBA_00191	6.82e-38	-	-	-	M	-	-	-	biosynthesis protein
NIKBCBBA_00192	9.83e-107	-	-	-	-	-	-	-	-
NIKBCBBA_00193	5.31e-96	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NIKBCBBA_00194	4.88e-265	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NIKBCBBA_00195	4.12e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NIKBCBBA_00196	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NIKBCBBA_00197	1.79e-45	-	-	-	-	-	-	-	-
NIKBCBBA_00198	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
NIKBCBBA_00199	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NIKBCBBA_00200	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NIKBCBBA_00201	1.1e-185	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NIKBCBBA_00202	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIKBCBBA_00203	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIKBCBBA_00204	3.09e-133	-	-	-	-	-	-	-	-
NIKBCBBA_00205	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIKBCBBA_00206	4.63e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NIKBCBBA_00207	9.88e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NIKBCBBA_00208	1.2e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIKBCBBA_00209	2.81e-96	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NIKBCBBA_00210	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NIKBCBBA_00211	2.64e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NIKBCBBA_00212	5.95e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIKBCBBA_00213	8.28e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIKBCBBA_00214	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
NIKBCBBA_00215	1.1e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIKBCBBA_00216	2.21e-162	ybbR	-	-	S	-	-	-	YbbR-like protein
NIKBCBBA_00217	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIKBCBBA_00218	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIKBCBBA_00219	3.51e-68	-	-	-	-	-	-	-	-
NIKBCBBA_00220	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NIKBCBBA_00221	1.68e-101	-	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_00222	4.13e-186	-	-	-	S	-	-	-	Cof-like hydrolase
NIKBCBBA_00223	2.27e-108	lytE	-	-	M	-	-	-	Lysin motif
NIKBCBBA_00225	1.56e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NIKBCBBA_00226	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NIKBCBBA_00227	3.69e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NIKBCBBA_00228	6.73e-151	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NIKBCBBA_00229	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NIKBCBBA_00230	2.69e-36	-	-	-	-	-	-	-	-
NIKBCBBA_00232	3.16e-11	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NIKBCBBA_00233	2.61e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
NIKBCBBA_00234	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIKBCBBA_00235	3.24e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
NIKBCBBA_00236	2.51e-207	-	-	-	EG	-	-	-	EamA-like transporter family
NIKBCBBA_00237	9.2e-130	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NIKBCBBA_00238	1.47e-69	-	-	-	S	-	-	-	Cupredoxin-like domain
NIKBCBBA_00239	1.81e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
NIKBCBBA_00240	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NIKBCBBA_00241	1.28e-112	-	-	-	-	-	-	-	-
NIKBCBBA_00243	1.02e-72	-	-	-	-	-	-	-	-
NIKBCBBA_00244	2.69e-31	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NIKBCBBA_00246	9.47e-125	-	-	-	-	-	-	-	-
NIKBCBBA_00247	0.0	-	-	-	M	-	-	-	domain protein
NIKBCBBA_00248	2.66e-62	-	-	-	-	-	-	-	-
NIKBCBBA_00249	1.62e-230	ampC	-	-	V	-	-	-	Beta-lactamase
NIKBCBBA_00250	2.07e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
NIKBCBBA_00251	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NIKBCBBA_00252	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NIKBCBBA_00253	4.42e-294	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
NIKBCBBA_00254	1.98e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NIKBCBBA_00255	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
NIKBCBBA_00256	2.77e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NIKBCBBA_00257	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIKBCBBA_00258	4.89e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIKBCBBA_00259	1.04e-248	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIKBCBBA_00260	8.62e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIKBCBBA_00261	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIKBCBBA_00262	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIKBCBBA_00263	2.61e-243	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NIKBCBBA_00264	1.41e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NIKBCBBA_00265	6.58e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NIKBCBBA_00266	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NIKBCBBA_00267	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIKBCBBA_00268	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIKBCBBA_00269	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIKBCBBA_00270	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIKBCBBA_00271	4.34e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIKBCBBA_00272	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIKBCBBA_00273	1.05e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NIKBCBBA_00274	2.5e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NIKBCBBA_00275	3e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIKBCBBA_00276	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NIKBCBBA_00277	3.77e-56	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NIKBCBBA_00278	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NIKBCBBA_00279	1.35e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NIKBCBBA_00280	1.66e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NIKBCBBA_00281	0.000599	-	-	-	-	-	-	-	-
NIKBCBBA_00283	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NIKBCBBA_00284	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
NIKBCBBA_00285	5.26e-261	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
NIKBCBBA_00286	4.57e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIKBCBBA_00287	6.9e-200	mleR	-	-	K	-	-	-	LysR family
NIKBCBBA_00288	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NIKBCBBA_00289	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIKBCBBA_00290	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NIKBCBBA_00291	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NIKBCBBA_00292	2.81e-202	-	-	-	K	-	-	-	LysR family
NIKBCBBA_00293	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NIKBCBBA_00294	9.06e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
NIKBCBBA_00295	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_00296	1.28e-230	-	-	-	I	-	-	-	Alpha beta
NIKBCBBA_00297	2.66e-132	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NIKBCBBA_00298	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIKBCBBA_00300	5.05e-202	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIKBCBBA_00301	8.7e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NIKBCBBA_00302	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NIKBCBBA_00303	8.16e-93	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NIKBCBBA_00304	1.16e-74	-	-	-	-	-	-	-	-
NIKBCBBA_00305	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIKBCBBA_00306	6.12e-277	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NIKBCBBA_00307	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIKBCBBA_00308	2.13e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIKBCBBA_00309	6.38e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIKBCBBA_00310	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00311	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NIKBCBBA_00312	2.34e-142	-	-	-	S	-	-	-	VIT family
NIKBCBBA_00313	3.34e-148	-	-	-	S	-	-	-	membrane
NIKBCBBA_00314	2.73e-210	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NIKBCBBA_00315	2.22e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NIKBCBBA_00316	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NIKBCBBA_00317	2.01e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
NIKBCBBA_00318	8.68e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NIKBCBBA_00319	3.81e-151	-	-	-	I	-	-	-	phosphatase
NIKBCBBA_00320	1.22e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NIKBCBBA_00321	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NIKBCBBA_00322	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NIKBCBBA_00328	1.05e-225	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
NIKBCBBA_00329	7.35e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NIKBCBBA_00330	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NIKBCBBA_00331	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIKBCBBA_00332	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIKBCBBA_00333	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIKBCBBA_00334	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIKBCBBA_00335	6.39e-261	-	-	-	-	-	-	-	-
NIKBCBBA_00336	8.01e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
NIKBCBBA_00337	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIKBCBBA_00338	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIKBCBBA_00339	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIKBCBBA_00340	1.76e-295	isp	-	-	L	-	-	-	Transposase
NIKBCBBA_00341	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NIKBCBBA_00342	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIKBCBBA_00343	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NIKBCBBA_00344	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIKBCBBA_00345	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIKBCBBA_00346	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIKBCBBA_00347	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIKBCBBA_00348	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIKBCBBA_00349	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIKBCBBA_00350	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NIKBCBBA_00351	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIKBCBBA_00352	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIKBCBBA_00353	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIKBCBBA_00354	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIKBCBBA_00355	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIKBCBBA_00356	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIKBCBBA_00357	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIKBCBBA_00358	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIKBCBBA_00359	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIKBCBBA_00360	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NIKBCBBA_00361	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NIKBCBBA_00362	1.17e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIKBCBBA_00363	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIKBCBBA_00364	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIKBCBBA_00365	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIKBCBBA_00366	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIKBCBBA_00367	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIKBCBBA_00368	1.15e-82	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NIKBCBBA_00369	4.9e-177	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIKBCBBA_00370	9.17e-186	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIKBCBBA_00371	7.6e-177	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIKBCBBA_00372	8.69e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIKBCBBA_00373	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIKBCBBA_00374	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NIKBCBBA_00375	6.34e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NIKBCBBA_00376	7.23e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NIKBCBBA_00377	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIKBCBBA_00378	1.87e-271	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NIKBCBBA_00379	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NIKBCBBA_00380	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIKBCBBA_00381	6.4e-260	camS	-	-	S	-	-	-	sex pheromone
NIKBCBBA_00382	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIKBCBBA_00383	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIKBCBBA_00384	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIKBCBBA_00385	1.91e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NIKBCBBA_00386	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIKBCBBA_00387	2.27e-91	-	-	-	L	ko:K02057,ko:K03546	-	ko00000,ko00002,ko02000,ko03400	ATPase involved in DNA repair
NIKBCBBA_00388	9.66e-111	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NIKBCBBA_00389	1.18e-91	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NIKBCBBA_00390	2.68e-218	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
NIKBCBBA_00391	2.96e-56	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NIKBCBBA_00392	7.1e-58	-	-	-	-	-	-	-	-
NIKBCBBA_00393	8.23e-119	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NIKBCBBA_00394	1.02e-296	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
NIKBCBBA_00395	6.31e-111	-	-	-	-	-	-	-	-
NIKBCBBA_00396	5.87e-147	pnb	-	-	C	-	-	-	nitroreductase
NIKBCBBA_00397	4.19e-78	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
NIKBCBBA_00398	5.46e-206	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
NIKBCBBA_00399	2.09e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NIKBCBBA_00400	3.95e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
NIKBCBBA_00401	4.15e-24	-	-	-	-	-	-	-	-
NIKBCBBA_00402	3.84e-246	-	-	-	P	-	-	-	Major Facilitator Superfamily
NIKBCBBA_00403	7.57e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NIKBCBBA_00404	1.35e-97	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
NIKBCBBA_00405	3.85e-239	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NIKBCBBA_00406	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NIKBCBBA_00407	3.59e-211	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NIKBCBBA_00408	1.84e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NIKBCBBA_00409	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NIKBCBBA_00410	4.39e-244	mocA	-	-	S	-	-	-	Oxidoreductase
NIKBCBBA_00411	7.11e-293	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NIKBCBBA_00413	3.18e-261	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIKBCBBA_00414	1.42e-72	-	-	-	-	-	-	-	-
NIKBCBBA_00415	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NIKBCBBA_00416	2.72e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NIKBCBBA_00417	1.66e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NIKBCBBA_00418	6.6e-279	arcT	-	-	E	-	-	-	Aminotransferase
NIKBCBBA_00419	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NIKBCBBA_00420	0.0	potE	-	-	E	-	-	-	Amino Acid
NIKBCBBA_00421	4.8e-195	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NIKBCBBA_00422	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NIKBCBBA_00423	1.03e-41	-	-	-	-	-	-	-	-
NIKBCBBA_00424	8.21e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NIKBCBBA_00425	6.67e-190	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NIKBCBBA_00426	1.96e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NIKBCBBA_00427	2.32e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
NIKBCBBA_00428	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
NIKBCBBA_00440	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIKBCBBA_00441	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIKBCBBA_00443	9.4e-197	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NIKBCBBA_00444	1.33e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIKBCBBA_00445	2.9e-157	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
NIKBCBBA_00446	6.47e-149	-	-	-	S	-	-	-	Membrane
NIKBCBBA_00447	1.09e-250	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NIKBCBBA_00448	4.72e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NIKBCBBA_00449	3.7e-19	-	-	-	-	-	-	-	-
NIKBCBBA_00450	2.83e-121	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NIKBCBBA_00451	7.77e-103	-	-	-	-	-	-	-	-
NIKBCBBA_00452	1.92e-158	-	-	-	M	-	-	-	Lysin motif
NIKBCBBA_00453	3.71e-246	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_00454	1.11e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NIKBCBBA_00455	9.26e-290	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NIKBCBBA_00456	3.42e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NIKBCBBA_00457	1e-163	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
NIKBCBBA_00458	2.2e-128	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain
NIKBCBBA_00459	4.53e-37	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NIKBCBBA_00460	4.31e-199	-	-	-	J	-	-	-	Methyltransferase
NIKBCBBA_00461	5.13e-91	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIKBCBBA_00463	7.3e-72	-	-	-	-	-	-	-	-
NIKBCBBA_00464	3.13e-73	-	-	-	D	-	-	-	ftsk spoiiie
NIKBCBBA_00466	6.44e-19	-	-	-	-	-	-	-	-
NIKBCBBA_00467	0.0	-	-	-	L	-	-	-	helicase
NIKBCBBA_00468	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NIKBCBBA_00470	3.59e-280	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
NIKBCBBA_00471	2.79e-224	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NIKBCBBA_00472	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIKBCBBA_00473	3.56e-17	-	-	-	EG	-	-	-	EamA-like transporter family
NIKBCBBA_00474	1.23e-127	-	-	-	EG	-	-	-	EamA-like transporter family
NIKBCBBA_00475	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NIKBCBBA_00476	9.61e-305	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NIKBCBBA_00477	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NIKBCBBA_00478	6.09e-144	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NIKBCBBA_00479	2.62e-159	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NIKBCBBA_00480	1.89e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIKBCBBA_00481	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_00482	9.04e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NIKBCBBA_00483	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIKBCBBA_00484	3.99e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIKBCBBA_00485	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NIKBCBBA_00486	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIKBCBBA_00488	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIKBCBBA_00489	9.24e-305	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
NIKBCBBA_00490	1.83e-21	-	-	-	-	-	-	-	-
NIKBCBBA_00492	2.26e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NIKBCBBA_00493	1.51e-234	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NIKBCBBA_00494	4.79e-200	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NIKBCBBA_00495	1.5e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NIKBCBBA_00496	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIKBCBBA_00497	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIKBCBBA_00498	1.03e-19	-	-	-	-	-	-	-	-
NIKBCBBA_00499	6.92e-148	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NIKBCBBA_00500	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NIKBCBBA_00501	6.71e-113	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NIKBCBBA_00502	2.63e-23	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
NIKBCBBA_00503	1.13e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIKBCBBA_00504	1.78e-202	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NIKBCBBA_00505	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NIKBCBBA_00506	5.88e-174	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NIKBCBBA_00507	5.02e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NIKBCBBA_00508	3.29e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NIKBCBBA_00509	5.5e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIKBCBBA_00510	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIKBCBBA_00511	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NIKBCBBA_00512	2.47e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NIKBCBBA_00513	1.07e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIKBCBBA_00514	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIKBCBBA_00515	2.38e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIKBCBBA_00516	9.6e-146	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NIKBCBBA_00517	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NIKBCBBA_00518	2.05e-139	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NIKBCBBA_00519	3.39e-92	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_00520	1.32e-168	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_00521	5.73e-83	-	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_00522	1.07e-52	-	-	-	-	-	-	-	-
NIKBCBBA_00523	0.0	ydaO	-	-	E	-	-	-	amino acid
NIKBCBBA_00524	0.0	-	-	-	E	-	-	-	amino acid
NIKBCBBA_00525	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIKBCBBA_00526	7.46e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIKBCBBA_00527	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIKBCBBA_00528	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NIKBCBBA_00529	2.51e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIKBCBBA_00530	4.92e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIKBCBBA_00531	2.18e-173	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NIKBCBBA_00532	7.34e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIKBCBBA_00533	1.45e-280	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIKBCBBA_00534	1.92e-165	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIKBCBBA_00535	1.6e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIKBCBBA_00536	8.33e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NIKBCBBA_00537	6.03e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NIKBCBBA_00538	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIKBCBBA_00539	2.44e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NIKBCBBA_00540	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIKBCBBA_00541	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NIKBCBBA_00542	4.41e-169	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NIKBCBBA_00543	1.38e-194	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIKBCBBA_00544	3.06e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NIKBCBBA_00545	8.71e-234	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NIKBCBBA_00546	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NIKBCBBA_00547	9.77e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIKBCBBA_00548	1.1e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NIKBCBBA_00549	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIKBCBBA_00550	1.68e-61	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIKBCBBA_00551	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIKBCBBA_00552	1.71e-116	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIKBCBBA_00553	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NIKBCBBA_00554	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIKBCBBA_00555	2.2e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIKBCBBA_00556	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NIKBCBBA_00557	7.95e-171	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NIKBCBBA_00558	2.68e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NIKBCBBA_00559	2.29e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NIKBCBBA_00560	1.15e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIKBCBBA_00562	2.39e-64	-	-	-	-	-	-	-	-
NIKBCBBA_00563	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIKBCBBA_00564	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIKBCBBA_00565	2.97e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIKBCBBA_00566	8.26e-308	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NIKBCBBA_00568	8.48e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NIKBCBBA_00569	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIKBCBBA_00570	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIKBCBBA_00571	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NIKBCBBA_00572	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIKBCBBA_00573	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NIKBCBBA_00574	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIKBCBBA_00575	2.07e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIKBCBBA_00576	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIKBCBBA_00577	4.84e-258	yacL	-	-	S	-	-	-	domain protein
NIKBCBBA_00578	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIKBCBBA_00579	1.9e-126	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NIKBCBBA_00580	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NIKBCBBA_00581	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIKBCBBA_00582	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NIKBCBBA_00583	3.23e-176	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NIKBCBBA_00584	1.18e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00585	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIKBCBBA_00586	9.25e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NIKBCBBA_00587	8.55e-214	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIKBCBBA_00588	2.4e-169	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIKBCBBA_00589	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NIKBCBBA_00590	1.19e-231	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NIKBCBBA_00591	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NIKBCBBA_00593	1.03e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NIKBCBBA_00594	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NIKBCBBA_00595	5.9e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIKBCBBA_00596	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIKBCBBA_00597	2.05e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NIKBCBBA_00598	1.33e-166	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NIKBCBBA_00599	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NIKBCBBA_00600	4.55e-315	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_00601	3.81e-144	-	-	-	-	-	-	-	-
NIKBCBBA_00604	1.5e-192	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIKBCBBA_00605	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NIKBCBBA_00612	5.44e-244	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NIKBCBBA_00613	3.68e-282	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NIKBCBBA_00614	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIKBCBBA_00615	3.67e-198	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
NIKBCBBA_00616	4.77e-267	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
NIKBCBBA_00617	3.59e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NIKBCBBA_00618	6.18e-199	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
NIKBCBBA_00619	5.75e-206	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NIKBCBBA_00620	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIKBCBBA_00621	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NIKBCBBA_00622	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
NIKBCBBA_00623	1.86e-190	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NIKBCBBA_00624	6.88e-152	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NIKBCBBA_00626	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIKBCBBA_00627	3.09e-209	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NIKBCBBA_00628	2.46e-289	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NIKBCBBA_00629	1.02e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIKBCBBA_00630	3.15e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NIKBCBBA_00631	1.36e-220	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NIKBCBBA_00632	1.63e-146	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NIKBCBBA_00633	3.66e-108	-	-	-	-	-	-	-	-
NIKBCBBA_00634	4.38e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NIKBCBBA_00635	3.94e-45	-	-	-	-	-	-	-	-
NIKBCBBA_00636	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIKBCBBA_00637	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
NIKBCBBA_00638	4.49e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NIKBCBBA_00639	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIKBCBBA_00640	2.09e-50	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NIKBCBBA_00641	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NIKBCBBA_00642	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIKBCBBA_00643	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIKBCBBA_00644	2.39e-260	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIKBCBBA_00645	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NIKBCBBA_00646	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIKBCBBA_00647	2.12e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIKBCBBA_00648	3.32e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIKBCBBA_00649	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIKBCBBA_00650	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NIKBCBBA_00651	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NIKBCBBA_00652	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NIKBCBBA_00653	3.71e-154	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NIKBCBBA_00654	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NIKBCBBA_00655	6.68e-206	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIKBCBBA_00656	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NIKBCBBA_00657	4.09e-166	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NIKBCBBA_00658	4e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIKBCBBA_00659	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIKBCBBA_00660	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIKBCBBA_00661	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIKBCBBA_00662	1.58e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIKBCBBA_00663	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NIKBCBBA_00664	3.53e-69	-	-	-	-	-	-	-	-
NIKBCBBA_00665	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NIKBCBBA_00666	9.17e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NIKBCBBA_00667	6.89e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NIKBCBBA_00668	2.23e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NIKBCBBA_00669	9.86e-59	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIKBCBBA_00670	1.17e-304	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIKBCBBA_00671	5.39e-191	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIKBCBBA_00672	1.24e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIKBCBBA_00673	2.66e-92	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NIKBCBBA_00674	1.2e-138	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
NIKBCBBA_00675	1.18e-253	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NIKBCBBA_00676	9.05e-169	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NIKBCBBA_00677	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NIKBCBBA_00678	2.94e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NIKBCBBA_00679	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NIKBCBBA_00680	2.82e-146	-	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_00683	6.71e-113	-	-	-	S	-	-	-	Protein conserved in bacteria
NIKBCBBA_00684	2.4e-232	-	-	-	-	-	-	-	-
NIKBCBBA_00685	9.41e-201	-	-	-	-	-	-	-	-
NIKBCBBA_00686	7.62e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NIKBCBBA_00687	7.8e-129	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIKBCBBA_00688	1.6e-115	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NIKBCBBA_00689	1.95e-46	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NIKBCBBA_00690	4.64e-70	-	-	-	S	-	-	-	Bacteriophage holin family
NIKBCBBA_00693	2.26e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
NIKBCBBA_00696	1.46e-67	-	-	-	M	-	-	-	Prophage endopeptidase tail
NIKBCBBA_00698	3.77e-127	-	-	-	S	-	-	-	peptidoglycan catabolic process
NIKBCBBA_00699	3.24e-42	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
NIKBCBBA_00700	3.83e-12	-	-	-	-	-	-	-	-
NIKBCBBA_00701	9.01e-51	-	-	-	N	-	-	-	domain, Protein
NIKBCBBA_00702	2.1e-16	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
NIKBCBBA_00704	4.71e-38	-	-	-	S	-	-	-	Minor capsid protein
NIKBCBBA_00706	4.62e-124	-	-	-	-	-	-	-	-
NIKBCBBA_00707	2.98e-28	-	-	-	S	-	-	-	Phage minor structural protein GP20
NIKBCBBA_00709	6.41e-113	-	-	-	S	-	-	-	Phage minor capsid protein 2
NIKBCBBA_00710	2.66e-155	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NIKBCBBA_00711	1.81e-164	-	-	-	L	ko:K06909	-	ko00000	Phage terminase, large subunit
NIKBCBBA_00712	1.86e-124	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NIKBCBBA_00715	1.24e-30	-	-	-	-	-	-	-	-
NIKBCBBA_00720	1.3e-104	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
NIKBCBBA_00726	5.45e-164	-	-	-	L	-	-	-	DnaD domain protein
NIKBCBBA_00729	6.3e-21	-	-	-	-	-	-	-	-
NIKBCBBA_00734	1.54e-10	-	-	-	-	-	-	-	-
NIKBCBBA_00735	5.86e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIKBCBBA_00738	6.04e-35	-	-	-	-	-	-	-	-
NIKBCBBA_00739	2.49e-109	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIKBCBBA_00740	1.9e-104	-	-	-	S	-	-	-	Fic/DOC family
NIKBCBBA_00742	1.28e-18	-	-	-	-	-	-	-	-
NIKBCBBA_00743	2.38e-273	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIKBCBBA_00744	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIKBCBBA_00745	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NIKBCBBA_00746	1.04e-219	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIKBCBBA_00747	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NIKBCBBA_00748	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NIKBCBBA_00749	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NIKBCBBA_00750	8.46e-32	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NIKBCBBA_00751	1e-139	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NIKBCBBA_00752	2.2e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIKBCBBA_00753	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NIKBCBBA_00754	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NIKBCBBA_00755	0.0	-	-	-	S	-	-	-	membrane
NIKBCBBA_00756	1.05e-88	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NIKBCBBA_00757	2.47e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIKBCBBA_00758	2.8e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NIKBCBBA_00759	3.29e-146	-	-	-	M	-	-	-	PFAM NLP P60 protein
NIKBCBBA_00760	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIKBCBBA_00761	4.27e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIKBCBBA_00762	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIKBCBBA_00763	2.17e-118	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIKBCBBA_00764	9.06e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIKBCBBA_00765	2.27e-54	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NIKBCBBA_00766	4.34e-212	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIKBCBBA_00767	1.07e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIKBCBBA_00768	1.32e-291	-	-	-	V	-	-	-	MatE
NIKBCBBA_00769	0.0	potE	-	-	E	-	-	-	Amino Acid
NIKBCBBA_00770	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIKBCBBA_00771	9.72e-156	csrR	-	-	K	-	-	-	response regulator
NIKBCBBA_00772	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NIKBCBBA_00773	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NIKBCBBA_00774	3.19e-263	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NIKBCBBA_00775	3.4e-174	yqeM	-	-	Q	-	-	-	Methyltransferase
NIKBCBBA_00776	3.83e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIKBCBBA_00777	2.84e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NIKBCBBA_00778	7.5e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIKBCBBA_00779	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NIKBCBBA_00780	1.82e-277	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NIKBCBBA_00781	1.83e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NIKBCBBA_00782	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIKBCBBA_00783	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NIKBCBBA_00784	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIKBCBBA_00785	8.24e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NIKBCBBA_00786	7.42e-296	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NIKBCBBA_00787	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIKBCBBA_00788	3.01e-122	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIKBCBBA_00789	4.54e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIKBCBBA_00790	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIKBCBBA_00791	1.09e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NIKBCBBA_00792	1.31e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NIKBCBBA_00793	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NIKBCBBA_00794	2.07e-37	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NIKBCBBA_00795	1.49e-63	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
NIKBCBBA_00796	5.7e-153	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIKBCBBA_00797	2e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
NIKBCBBA_00798	2.19e-73	-	-	-	S	-	-	-	Small secreted protein
NIKBCBBA_00799	1.26e-215	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NIKBCBBA_00800	7.11e-228	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NIKBCBBA_00801	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NIKBCBBA_00802	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIKBCBBA_00803	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIKBCBBA_00804	7.75e-278	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NIKBCBBA_00805	9.03e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00806	1.43e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NIKBCBBA_00808	9.68e-177	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIKBCBBA_00809	0.0	yhaN	-	-	L	-	-	-	AAA domain
NIKBCBBA_00810	3.5e-271	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
NIKBCBBA_00811	1.4e-63	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NIKBCBBA_00812	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NIKBCBBA_00813	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NIKBCBBA_00814	1.02e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NIKBCBBA_00815	2.72e-210	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NIKBCBBA_00816	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_00817	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NIKBCBBA_00818	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIKBCBBA_00819	4.25e-248	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NIKBCBBA_00820	4.07e-287	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NIKBCBBA_00821	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIKBCBBA_00822	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NIKBCBBA_00823	9.36e-36	-	-	-	-	-	-	-	-
NIKBCBBA_00824	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NIKBCBBA_00825	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
NIKBCBBA_00826	9.48e-183	-	-	-	G	-	-	-	MucBP domain
NIKBCBBA_00827	9.82e-140	-	-	-	-	-	-	-	-
NIKBCBBA_00828	2.92e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00829	4.16e-85	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NIKBCBBA_00830	0.0	-	-	-	S	-	-	-	Peptidase, M23
NIKBCBBA_00831	0.0	-	-	-	M	-	-	-	NlpC/P60 family
NIKBCBBA_00832	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIKBCBBA_00833	8.13e-286	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NIKBCBBA_00834	1.07e-231	yueF	-	-	S	-	-	-	AI-2E family transporter
NIKBCBBA_00835	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
NIKBCBBA_00837	1.73e-21	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIKBCBBA_00838	9.55e-23	-	-	-	UW	-	-	-	Tetratricopeptide repeat
NIKBCBBA_00839	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIKBCBBA_00840	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NIKBCBBA_00841	1.1e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NIKBCBBA_00842	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIKBCBBA_00843	4.75e-117	-	-	-	-	-	-	-	-
NIKBCBBA_00844	4.81e-50	-	-	-	-	-	-	-	-
NIKBCBBA_00845	2.26e-129	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NIKBCBBA_00846	7.29e-157	-	-	-	-	-	-	-	-
NIKBCBBA_00847	1.48e-85	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIKBCBBA_00848	2.41e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NIKBCBBA_00849	1.31e-189	epsB	-	-	M	-	-	-	biosynthesis protein
NIKBCBBA_00850	1.57e-158	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NIKBCBBA_00851	4.89e-132	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
NIKBCBBA_00852	3.2e-95	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
NIKBCBBA_00853	7.21e-72	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
NIKBCBBA_00854	1.08e-170	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NIKBCBBA_00855	9.84e-64	-	-	-	M	-	-	-	Glycosyl transferases group 1
NIKBCBBA_00856	9.81e-105	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
NIKBCBBA_00857	1.99e-46	-	-	-	-	-	-	-	-
NIKBCBBA_00858	3.17e-47	cysE_1	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
NIKBCBBA_00859	3.61e-86	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
NIKBCBBA_00860	1.47e-132	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NIKBCBBA_00861	3.85e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIKBCBBA_00862	4.85e-159	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIKBCBBA_00863	4.99e-104	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NIKBCBBA_00864	2.3e-127	-	-	-	K	-	-	-	UTRA
NIKBCBBA_00865	6.07e-211	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NIKBCBBA_00866	3.35e-306	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
NIKBCBBA_00867	4.97e-149	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
NIKBCBBA_00869	8.13e-35	-	-	-	-	-	-	-	-
NIKBCBBA_00870	8.26e-57	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NIKBCBBA_00872	4.82e-282	-	-	-	V	-	-	-	ATPase associated with various cellular activities
NIKBCBBA_00873	1.26e-51	-	-	-	-	-	-	-	-
NIKBCBBA_00875	4.72e-213	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NIKBCBBA_00876	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NIKBCBBA_00878	2.32e-43	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NIKBCBBA_00880	3.03e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NIKBCBBA_00881	1.14e-224	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NIKBCBBA_00882	7.86e-266	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NIKBCBBA_00883	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NIKBCBBA_00884	2.39e-131	-	-	-	L	-	-	-	nuclease
NIKBCBBA_00885	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NIKBCBBA_00886	3.03e-91	-	-	-	-	-	-	-	-
NIKBCBBA_00887	4.61e-132	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NIKBCBBA_00888	3.24e-157	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIKBCBBA_00889	2.18e-56	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NIKBCBBA_00890	6.02e-120	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NIKBCBBA_00891	0.0	-	-	-	-	-	-	-	-
NIKBCBBA_00892	0.0	-	-	-	-	-	-	-	-
NIKBCBBA_00894	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_00895	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIKBCBBA_00896	3.15e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_00897	9.75e-283	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NIKBCBBA_00898	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
NIKBCBBA_00899	1.43e-219	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NIKBCBBA_00900	3.31e-205	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NIKBCBBA_00901	6.74e-158	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NIKBCBBA_00902	3.97e-195	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NIKBCBBA_00903	9.73e-179	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NIKBCBBA_00904	8.93e-194	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NIKBCBBA_00905	7.96e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NIKBCBBA_00906	2.9e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIKBCBBA_00907	3.49e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NIKBCBBA_00908	5.64e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIKBCBBA_00909	1.33e-297	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NIKBCBBA_00910	6.72e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NIKBCBBA_00911	1.89e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NIKBCBBA_00912	4.78e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
NIKBCBBA_00913	7.28e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIKBCBBA_00914	9.76e-161	vanR	-	-	K	-	-	-	response regulator
NIKBCBBA_00915	3.73e-264	hpk31	-	-	T	-	-	-	Histidine kinase
NIKBCBBA_00916	1.97e-185	-	-	-	E	-	-	-	AzlC protein
NIKBCBBA_00917	4.73e-69	-	-	-	S	-	-	-	branched-chain amino acid
NIKBCBBA_00918	6.13e-181	-	-	-	K	-	-	-	LysR substrate binding domain
NIKBCBBA_00919	1.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NIKBCBBA_00920	2.04e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIKBCBBA_00921	1.36e-117	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIKBCBBA_00922	6.19e-83	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIKBCBBA_00923	1.13e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIKBCBBA_00924	4.32e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIKBCBBA_00925	7.17e-146	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NIKBCBBA_00926	6.97e-293	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NIKBCBBA_00927	4.02e-219	ydbI	-	-	K	-	-	-	AI-2E family transporter
NIKBCBBA_00928	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NIKBCBBA_00929	2.57e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIKBCBBA_00930	2.04e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIKBCBBA_00931	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIKBCBBA_00932	1.01e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NIKBCBBA_00933	7.76e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIKBCBBA_00934	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIKBCBBA_00935	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIKBCBBA_00936	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIKBCBBA_00937	1.65e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NIKBCBBA_00938	3.93e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIKBCBBA_00939	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NIKBCBBA_00940	1.94e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NIKBCBBA_00941	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIKBCBBA_00942	8.45e-224	-	-	-	-	-	-	-	-
NIKBCBBA_00943	1.21e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIKBCBBA_00944	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_00945	2.26e-265	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NIKBCBBA_00946	9.45e-160	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIKBCBBA_00948	1.32e-125	-	-	-	-	-	-	-	-
NIKBCBBA_00949	7.22e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIKBCBBA_00950	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NIKBCBBA_00951	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NIKBCBBA_00952	2.67e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIKBCBBA_00953	7.59e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIKBCBBA_00954	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIKBCBBA_00955	4.93e-20	-	-	-	-	-	-	-	-
NIKBCBBA_00956	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NIKBCBBA_00957	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NIKBCBBA_00958	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIKBCBBA_00959	2.63e-301	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIKBCBBA_00960	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIKBCBBA_00961	1.4e-205	-	-	-	S	-	-	-	Tetratricopeptide repeat
NIKBCBBA_00962	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIKBCBBA_00963	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIKBCBBA_00964	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NIKBCBBA_00965	8.79e-198	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NIKBCBBA_00966	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NIKBCBBA_00967	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NIKBCBBA_00968	4.17e-123	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NIKBCBBA_00969	3.73e-26	-	-	-	-	-	-	-	-
NIKBCBBA_00970	5.6e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NIKBCBBA_00971	2.55e-95	-	-	-	-	-	-	-	-
NIKBCBBA_00972	3.33e-284	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NIKBCBBA_00973	1.64e-170	-	-	-	V	-	-	-	Beta-lactamase enzyme family
NIKBCBBA_00974	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
NIKBCBBA_00975	1.05e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NIKBCBBA_00976	0.0	arcT	-	-	E	-	-	-	Dipeptidase
NIKBCBBA_00977	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NIKBCBBA_00978	2.9e-225	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NIKBCBBA_00979	3.38e-208	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NIKBCBBA_00980	1.14e-168	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIKBCBBA_00981	5.59e-228	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NIKBCBBA_00982	5.88e-121	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NIKBCBBA_00983	5.58e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NIKBCBBA_00984	1.33e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NIKBCBBA_00985	7.69e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NIKBCBBA_00986	1.02e-102	-	-	-	Q	-	-	-	Methyltransferase
NIKBCBBA_00987	4.64e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
NIKBCBBA_00988	7.23e-300	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NIKBCBBA_00989	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NIKBCBBA_00990	1.41e-165	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NIKBCBBA_00991	5e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NIKBCBBA_00992	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIKBCBBA_00993	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NIKBCBBA_00994	3.93e-195	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NIKBCBBA_00995	1.64e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NIKBCBBA_00996	2.14e-172	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
NIKBCBBA_00997	3.28e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NIKBCBBA_00998	9.97e-185	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NIKBCBBA_00999	1.35e-237	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
NIKBCBBA_01000	1.46e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIKBCBBA_01001	2e-56	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIKBCBBA_01002	3.9e-208	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NIKBCBBA_01003	2.42e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NIKBCBBA_01004	2.4e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NIKBCBBA_01005	2.54e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NIKBCBBA_01006	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
NIKBCBBA_01007	1.15e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
NIKBCBBA_01008	8.76e-63	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
NIKBCBBA_01009	3.59e-128	-	-	-	S	-	-	-	AmiS/UreI family transporter
NIKBCBBA_01010	1.03e-283	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NIKBCBBA_01012	1.19e-231	-	-	-	-	-	-	-	-
NIKBCBBA_01013	2.32e-126	-	-	-	K	-	-	-	acetyltransferase
NIKBCBBA_01014	5.12e-181	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NIKBCBBA_01016	2.2e-220	-	-	-	-	-	-	-	-
NIKBCBBA_01017	2.78e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIKBCBBA_01018	4.05e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NIKBCBBA_01019	2.73e-222	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIKBCBBA_01020	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NIKBCBBA_01021	4.87e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NIKBCBBA_01022	1.66e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIKBCBBA_01023	1.32e-120	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NIKBCBBA_01024	2.54e-145	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NIKBCBBA_01025	5.54e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIKBCBBA_01026	1.3e-194	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NIKBCBBA_01028	3.12e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
NIKBCBBA_01029	1.13e-54	-	-	-	-	-	-	-	-
NIKBCBBA_01030	9.69e-99	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
NIKBCBBA_01031	4.27e-60	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NIKBCBBA_01032	1.41e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NIKBCBBA_01033	2.89e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NIKBCBBA_01034	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NIKBCBBA_01035	7.42e-175	-	-	-	-	-	-	-	-
NIKBCBBA_01036	1.34e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NIKBCBBA_01037	1.35e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NIKBCBBA_01038	4.51e-76	-	-	-	-	-	-	-	-
NIKBCBBA_01039	5.98e-69	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIKBCBBA_01040	8.47e-186	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NIKBCBBA_01041	1.83e-194	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NIKBCBBA_01042	6.01e-99	ykuL	-	-	S	-	-	-	(CBS) domain
NIKBCBBA_01043	1.85e-117	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NIKBCBBA_01044	1.12e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIKBCBBA_01045	3.76e-177	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NIKBCBBA_01046	1.43e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NIKBCBBA_01047	9.61e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NIKBCBBA_01048	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIKBCBBA_01049	4.14e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
NIKBCBBA_01050	7.57e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NIKBCBBA_01051	1.04e-99	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIKBCBBA_01052	3.83e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NIKBCBBA_01053	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIKBCBBA_01054	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIKBCBBA_01055	7.18e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NIKBCBBA_01056	2.91e-59	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NIKBCBBA_01057	2.02e-231	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIKBCBBA_01058	4.74e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIKBCBBA_01059	3.57e-130	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIKBCBBA_01060	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIKBCBBA_01061	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIKBCBBA_01062	2.53e-273	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NIKBCBBA_01063	8.57e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIKBCBBA_01064	1.18e-275	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NIKBCBBA_01065	3.89e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIKBCBBA_01066	3.61e-191	-	-	-	S	-	-	-	Helix-turn-helix domain
NIKBCBBA_01067	7.13e-313	ymfH	-	-	S	-	-	-	Peptidase M16
NIKBCBBA_01068	1.79e-286	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NIKBCBBA_01069	1.16e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NIKBCBBA_01070	2.41e-150	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01071	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NIKBCBBA_01072	1.39e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NIKBCBBA_01073	2.12e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NIKBCBBA_01074	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NIKBCBBA_01075	9.91e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NIKBCBBA_01076	9.5e-300	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NIKBCBBA_01077	3.14e-295	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NIKBCBBA_01078	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NIKBCBBA_01079	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NIKBCBBA_01080	1.98e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NIKBCBBA_01081	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NIKBCBBA_01082	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIKBCBBA_01083	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIKBCBBA_01084	2.37e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NIKBCBBA_01085	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIKBCBBA_01086	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIKBCBBA_01087	5.26e-299	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NIKBCBBA_01088	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
NIKBCBBA_01089	2.28e-229	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
NIKBCBBA_01090	8.5e-124	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NIKBCBBA_01091	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NIKBCBBA_01092	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NIKBCBBA_01093	3.52e-173	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NIKBCBBA_01094	1.98e-178	-	-	-	S	-	-	-	Membrane
NIKBCBBA_01095	4.73e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
NIKBCBBA_01096	1.97e-28	-	-	-	-	-	-	-	-
NIKBCBBA_01097	3.23e-108	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NIKBCBBA_01098	1.27e-305	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NIKBCBBA_01099	4.22e-60	-	-	-	-	-	-	-	-
NIKBCBBA_01100	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
NIKBCBBA_01101	2.82e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
NIKBCBBA_01102	9.07e-196	yvgN	-	-	S	-	-	-	Aldo keto reductase
NIKBCBBA_01103	1.66e-222	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NIKBCBBA_01104	8.83e-101	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NIKBCBBA_01105	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NIKBCBBA_01106	6.65e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NIKBCBBA_01107	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
NIKBCBBA_01108	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIKBCBBA_01109	8.65e-183	-	-	-	K	-	-	-	transcriptional regulator, ArsR family
NIKBCBBA_01110	5.35e-221	abf	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NIKBCBBA_01111	1.58e-275	lacY	-	-	G	ko:K02532	-	ko00000,ko02000	Oligosaccharide H symporter
NIKBCBBA_01112	2.47e-189	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NIKBCBBA_01113	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NIKBCBBA_01114	2.73e-222	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIKBCBBA_01115	1.62e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIKBCBBA_01116	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01117	6.79e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01118	3.04e-221	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NIKBCBBA_01119	4.34e-110	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
NIKBCBBA_01120	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
NIKBCBBA_01121	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NIKBCBBA_01122	2.89e-51	-	-	-	-	-	-	-	-
NIKBCBBA_01123	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIKBCBBA_01125	8.77e-282	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NIKBCBBA_01126	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
NIKBCBBA_01127	6.9e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
NIKBCBBA_01128	2.22e-231	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIKBCBBA_01129	1.39e-276	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NIKBCBBA_01130	8.62e-09	-	-	-	G	-	-	-	PFAM cytochrome
NIKBCBBA_01131	1.12e-36	-	-	-	S	-	-	-	Cytochrome B5
NIKBCBBA_01132	2.66e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
NIKBCBBA_01133	3.86e-157	-	-	-	GM	-	-	-	NmrA-like family
NIKBCBBA_01134	7.56e-67	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIKBCBBA_01135	5.3e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NIKBCBBA_01136	8.49e-105	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIKBCBBA_01137	6.84e-293	-	-	-	-	-	-	-	-
NIKBCBBA_01138	8.49e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NIKBCBBA_01139	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NIKBCBBA_01140	9.77e-144	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
NIKBCBBA_01141	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NIKBCBBA_01142	5.34e-63	ywnA	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_01143	7.83e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NIKBCBBA_01144	1.43e-40	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NIKBCBBA_01145	1.01e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NIKBCBBA_01146	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NIKBCBBA_01147	1.22e-145	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NIKBCBBA_01148	1.02e-240	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
NIKBCBBA_01149	1.08e-112	-	-	-	-	-	-	-	-
NIKBCBBA_01150	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
NIKBCBBA_01151	1.58e-166	-	-	-	T	-	-	-	EAL domain
NIKBCBBA_01152	9.8e-158	-	-	-	F	-	-	-	glutamine amidotransferase
NIKBCBBA_01153	9.48e-128	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
NIKBCBBA_01154	5.48e-203	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NIKBCBBA_01155	1.24e-182	-	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_01156	9.05e-232	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NIKBCBBA_01157	1.5e-36	-	-	-	H	-	-	-	Riboflavin biosynthesis protein RibD
NIKBCBBA_01158	1.22e-26	-	-	-	H	-	-	-	Riboflavin biosynthesis protein RibD
NIKBCBBA_01159	1.02e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NIKBCBBA_01160	2.76e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NIKBCBBA_01161	9.3e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NIKBCBBA_01162	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NIKBCBBA_01163	6.11e-177	-	-	-	S	-	-	-	Alpha beta hydrolase
NIKBCBBA_01164	5.85e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NIKBCBBA_01165	4.47e-196	lysR	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_01166	1.55e-110	-	-	-	C	-	-	-	Flavodoxin
NIKBCBBA_01167	1.78e-207	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NIKBCBBA_01168	6.39e-18	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NIKBCBBA_01169	9.28e-110	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
NIKBCBBA_01170	1.61e-212	-	-	-	C	-	-	-	nadph quinone reductase
NIKBCBBA_01171	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NIKBCBBA_01172	2.12e-26	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NIKBCBBA_01173	5.11e-140	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
NIKBCBBA_01174	5.37e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NIKBCBBA_01175	3.82e-270	-	-	-	T	-	-	-	GHKL domain
NIKBCBBA_01176	1e-147	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NIKBCBBA_01177	1.32e-147	-	-	-	H	-	-	-	RibD C-terminal domain
NIKBCBBA_01182	1.84e-269	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NIKBCBBA_01183	2e-154	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NIKBCBBA_01184	5.16e-115	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NIKBCBBA_01185	9.89e-86	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIKBCBBA_01186	4.98e-250	flp	-	-	V	-	-	-	Beta-lactamase
NIKBCBBA_01187	4.14e-119	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NIKBCBBA_01188	1.13e-148	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NIKBCBBA_01189	2.24e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
NIKBCBBA_01190	3.11e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NIKBCBBA_01191	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
NIKBCBBA_01192	0.0	-	-	-	S	-	-	-	amidohydrolase
NIKBCBBA_01193	3.11e-128	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIKBCBBA_01195	2.97e-209	-	-	-	S	-	-	-	reductase
NIKBCBBA_01196	2.46e-110	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
NIKBCBBA_01197	5.76e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NIKBCBBA_01198	1.49e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NIKBCBBA_01199	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIKBCBBA_01200	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NIKBCBBA_01201	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIKBCBBA_01202	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIKBCBBA_01203	4.04e-166	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NIKBCBBA_01204	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIKBCBBA_01205	2.81e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIKBCBBA_01206	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NIKBCBBA_01207	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIKBCBBA_01208	1.35e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIKBCBBA_01209	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NIKBCBBA_01210	4.68e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIKBCBBA_01211	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIKBCBBA_01212	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIKBCBBA_01213	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NIKBCBBA_01214	1.46e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIKBCBBA_01215	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIKBCBBA_01224	3.73e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIKBCBBA_01225	1.12e-303	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NIKBCBBA_01226	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NIKBCBBA_01227	2.77e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIKBCBBA_01228	1.08e-191	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
NIKBCBBA_01229	3.55e-71	-	-	-	M	-	-	-	LysM domain protein
NIKBCBBA_01230	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
NIKBCBBA_01231	9.23e-137	-	-	-	M	-	-	-	LysM domain protein
NIKBCBBA_01232	4.7e-189	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NIKBCBBA_01233	3.83e-296	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NIKBCBBA_01234	9.31e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NIKBCBBA_01235	4.13e-193	yeaE	-	-	S	-	-	-	Aldo keto
NIKBCBBA_01236	3.81e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NIKBCBBA_01237	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
NIKBCBBA_01238	1.17e-94	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NIKBCBBA_01239	3.8e-106	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NIKBCBBA_01240	7.03e-33	-	-	-	-	-	-	-	-
NIKBCBBA_01241	3.94e-133	-	-	-	V	-	-	-	VanZ like family
NIKBCBBA_01242	3.18e-73	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NIKBCBBA_01243	1.34e-18	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NIKBCBBA_01244	3.32e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NIKBCBBA_01245	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_01246	1.1e-121	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NIKBCBBA_01247	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIKBCBBA_01248	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NIKBCBBA_01249	1.7e-54	-	-	-	-	-	-	-	-
NIKBCBBA_01250	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NIKBCBBA_01251	4.82e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIKBCBBA_01252	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NIKBCBBA_01253	2.55e-111	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NIKBCBBA_01254	4.11e-218	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIKBCBBA_01255	2.07e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NIKBCBBA_01256	8.49e-144	-	-	-	-	-	-	-	-
NIKBCBBA_01257	9.83e-236	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NIKBCBBA_01258	8.45e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIKBCBBA_01259	2.54e-42	-	-	-	-	-	-	-	-
NIKBCBBA_01260	3.03e-141	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NIKBCBBA_01261	9.17e-59	-	-	-	-	-	-	-	-
NIKBCBBA_01265	2.05e-15	-	-	-	S	-	-	-	Phage regulatory protein, Rha family
NIKBCBBA_01266	2.91e-18	-	-	-	-	-	-	-	-
NIKBCBBA_01267	5.8e-06	-	-	-	K	-	-	-	transcriptional regulator, XRE family
NIKBCBBA_01268	5.95e-39	-	-	-	L	-	-	-	nuclease
NIKBCBBA_01271	1.05e-89	-	-	-	-	-	-	-	-
NIKBCBBA_01272	2.38e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIKBCBBA_01273	5.1e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NIKBCBBA_01274	6.78e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
NIKBCBBA_01275	2.39e-277	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NIKBCBBA_01276	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
NIKBCBBA_01277	2.27e-268	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
NIKBCBBA_01278	1.09e-59	-	-	-	-	-	-	-	-
NIKBCBBA_01279	1.49e-54	-	-	-	-	-	-	-	-
NIKBCBBA_01282	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
NIKBCBBA_01283	5.21e-225	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIKBCBBA_01284	2.02e-272	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NIKBCBBA_01285	2.98e-129	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NIKBCBBA_01286	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIKBCBBA_01287	1.86e-223	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIKBCBBA_01288	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NIKBCBBA_01289	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NIKBCBBA_01290	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NIKBCBBA_01291	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NIKBCBBA_01292	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
NIKBCBBA_01293	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NIKBCBBA_01294	8.53e-95	-	-	-	-	-	-	-	-
NIKBCBBA_01295	2.97e-303	isp	-	-	L	-	-	-	Transposase
NIKBCBBA_01296	4.45e-140	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NIKBCBBA_01298	2.1e-110	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIKBCBBA_01299	4.62e-117	-	-	-	-	-	-	-	-
NIKBCBBA_01300	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIKBCBBA_01301	1.29e-233	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIKBCBBA_01302	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NIKBCBBA_01303	1.31e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NIKBCBBA_01304	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NIKBCBBA_01305	2.92e-20	-	-	-	C	-	-	-	Aldo keto reductase
NIKBCBBA_01306	1.45e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NIKBCBBA_01307	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NIKBCBBA_01308	1.29e-261	-	-	-	P	-	-	-	Voltage gated chloride channel
NIKBCBBA_01309	3.03e-278	sptS	-	-	T	-	-	-	Histidine kinase
NIKBCBBA_01310	1.38e-147	dltr	-	-	K	-	-	-	response regulator
NIKBCBBA_01311	2.92e-111	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
NIKBCBBA_01312	2.83e-76	-	-	-	-	-	-	-	-
NIKBCBBA_01313	4.32e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NIKBCBBA_01314	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NIKBCBBA_01315	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NIKBCBBA_01316	1.02e-262	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NIKBCBBA_01317	2.36e-218	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIKBCBBA_01318	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NIKBCBBA_01319	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NIKBCBBA_01320	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIKBCBBA_01321	4.39e-133	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NIKBCBBA_01323	3.61e-232	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NIKBCBBA_01324	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NIKBCBBA_01325	8.68e-44	-	-	-	-	-	-	-	-
NIKBCBBA_01326	6.27e-270	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIKBCBBA_01327	6e-222	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIKBCBBA_01328	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
NIKBCBBA_01330	3.59e-305	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NIKBCBBA_01333	4.72e-165	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NIKBCBBA_01334	9.94e-218	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NIKBCBBA_01336	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NIKBCBBA_01337	1.08e-66	-	-	-	-	-	-	-	-
NIKBCBBA_01339	9.24e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NIKBCBBA_01340	4.66e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NIKBCBBA_01341	1.66e-199	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIKBCBBA_01342	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NIKBCBBA_01343	5.62e-185	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIKBCBBA_01344	1.46e-190	-	-	-	E	-	-	-	Glyoxalase-like domain
NIKBCBBA_01345	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NIKBCBBA_01346	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
NIKBCBBA_01347	1.83e-124	-	-	-	S	-	-	-	reductase
NIKBCBBA_01349	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIKBCBBA_01350	2.27e-114	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
NIKBCBBA_01351	1.66e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NIKBCBBA_01352	2.07e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NIKBCBBA_01353	4.13e-192	yycI	-	-	S	-	-	-	YycH protein
NIKBCBBA_01354	3.38e-315	yycH	-	-	S	-	-	-	YycH protein
NIKBCBBA_01355	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NIKBCBBA_01356	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NIKBCBBA_01358	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NIKBCBBA_01359	1.82e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NIKBCBBA_01361	5.56e-158	-	-	-	S	-	-	-	Fic/DOC family
NIKBCBBA_01362	2.04e-129	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NIKBCBBA_01363	3.6e-208	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NIKBCBBA_01364	1.24e-77	-	-	-	-	-	-	-	-
NIKBCBBA_01365	2.17e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_01366	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NIKBCBBA_01367	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NIKBCBBA_01368	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NIKBCBBA_01369	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_01370	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NIKBCBBA_01371	2.48e-258	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
NIKBCBBA_01372	4.44e-11	-	-	-	-	-	-	-	-
NIKBCBBA_01373	2.71e-199	-	-	-	GM	-	-	-	NAD(P)H-binding
NIKBCBBA_01374	1.29e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
NIKBCBBA_01375	7.22e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
NIKBCBBA_01376	4.83e-133	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIKBCBBA_01377	1.96e-178	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01378	2.45e-132	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NIKBCBBA_01379	3.02e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NIKBCBBA_01380	5.04e-315	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NIKBCBBA_01381	4.95e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NIKBCBBA_01382	6.12e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NIKBCBBA_01383	2.34e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIKBCBBA_01384	7.19e-199	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NIKBCBBA_01385	2.97e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NIKBCBBA_01386	1.7e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
NIKBCBBA_01387	5.31e-58	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
NIKBCBBA_01388	2.71e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIKBCBBA_01389	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
NIKBCBBA_01390	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIKBCBBA_01392	7.43e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIKBCBBA_01393	0.0	-	-	-	L	-	-	-	DNA helicase
NIKBCBBA_01394	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NIKBCBBA_01395	6.33e-227	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NIKBCBBA_01396	6.2e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NIKBCBBA_01397	6.22e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NIKBCBBA_01398	8.83e-285	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NIKBCBBA_01399	1.05e-225	-	-	-	-	-	-	-	-
NIKBCBBA_01400	4.16e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NIKBCBBA_01402	1.7e-201	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NIKBCBBA_01403	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIKBCBBA_01404	4.68e-194	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NIKBCBBA_01405	1.73e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIKBCBBA_01406	6.63e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIKBCBBA_01407	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NIKBCBBA_01408	4.52e-202	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIKBCBBA_01409	5.54e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NIKBCBBA_01410	4.85e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NIKBCBBA_01411	1.23e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NIKBCBBA_01412	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NIKBCBBA_01413	1.01e-310	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIKBCBBA_01414	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIKBCBBA_01415	4.24e-101	-	-	-	-	-	-	-	-
NIKBCBBA_01416	1.82e-187	yidA	-	-	S	-	-	-	hydrolase
NIKBCBBA_01417	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NIKBCBBA_01418	1.06e-191	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NIKBCBBA_01419	1.13e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NIKBCBBA_01420	2.68e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIKBCBBA_01421	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIKBCBBA_01422	1.52e-299	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIKBCBBA_01423	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NIKBCBBA_01424	8.07e-297	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIKBCBBA_01425	2.96e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIKBCBBA_01426	3.52e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NIKBCBBA_01427	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NIKBCBBA_01428	1.84e-192	-	-	-	G	-	-	-	Right handed beta helix region
NIKBCBBA_01429	1.95e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIKBCBBA_01430	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NIKBCBBA_01431	4.85e-151	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NIKBCBBA_01432	1.11e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIKBCBBA_01433	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NIKBCBBA_01434	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NIKBCBBA_01435	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIKBCBBA_01436	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIKBCBBA_01437	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NIKBCBBA_01438	5.64e-211	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NIKBCBBA_01439	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIKBCBBA_01440	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIKBCBBA_01441	6.38e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NIKBCBBA_01442	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIKBCBBA_01443	4.54e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NIKBCBBA_01444	7.67e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIKBCBBA_01445	2.34e-264	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIKBCBBA_01446	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NIKBCBBA_01447	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NIKBCBBA_01448	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
NIKBCBBA_01449	2.8e-186	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NIKBCBBA_01450	6.64e-146	-	-	-	S	-	-	-	(CBS) domain
NIKBCBBA_01451	1.61e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIKBCBBA_01452	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIKBCBBA_01453	1.67e-51	yabO	-	-	J	-	-	-	S4 domain protein
NIKBCBBA_01454	1.44e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NIKBCBBA_01455	6.71e-102	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NIKBCBBA_01456	2.33e-313	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIKBCBBA_01457	1.5e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NIKBCBBA_01458	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIKBCBBA_01459	4.59e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIKBCBBA_01460	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIKBCBBA_01461	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NIKBCBBA_01462	4.26e-109	-	-	-	-	-	-	-	-
NIKBCBBA_01466	3.41e-08	-	-	-	K	-	-	-	Helix-turn-helix domain
NIKBCBBA_01467	4.26e-54	-	-	-	D	-	-	-	nuclear chromosome segregation
NIKBCBBA_01471	5.81e-98	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
NIKBCBBA_01472	9.87e-190	-	-	-	-	-	-	-	-
NIKBCBBA_01473	0.0	-	-	-	-	-	-	-	-
NIKBCBBA_01475	8.38e-28	-	-	-	-	-	-	-	-
NIKBCBBA_01476	8.87e-158	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIKBCBBA_01477	1.23e-148	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NIKBCBBA_01478	9.36e-203	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIKBCBBA_01479	2.38e-57	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NIKBCBBA_01480	5.81e-307	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
NIKBCBBA_01481	1.22e-167	-	-	-	IQ	-	-	-	dehydrogenase reductase
NIKBCBBA_01482	1.85e-48	-	-	-	-	-	-	-	-
NIKBCBBA_01483	1.9e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NIKBCBBA_01484	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
NIKBCBBA_01485	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NIKBCBBA_01486	4.63e-231	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIKBCBBA_01488	4.85e-130	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NIKBCBBA_01489	1.79e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NIKBCBBA_01490	1.75e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIKBCBBA_01492	5.42e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
NIKBCBBA_01493	6.97e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
NIKBCBBA_01494	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NIKBCBBA_01496	7.75e-313	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NIKBCBBA_01497	1.11e-70	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NIKBCBBA_01498	8.63e-156	-	-	-	-	-	-	-	-
NIKBCBBA_01499	3.36e-164	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NIKBCBBA_01500	3.48e-24	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NIKBCBBA_01501	1.8e-249	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NIKBCBBA_01502	2.24e-203	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NIKBCBBA_01503	3.75e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIKBCBBA_01504	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NIKBCBBA_01505	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NIKBCBBA_01506	4.5e-71	-	-	-	-	-	-	-	-
NIKBCBBA_01507	3.02e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NIKBCBBA_01508	6.28e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIKBCBBA_01509	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NIKBCBBA_01510	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NIKBCBBA_01511	2.58e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIKBCBBA_01512	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIKBCBBA_01513	4.27e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIKBCBBA_01514	1.65e-183	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIKBCBBA_01515	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIKBCBBA_01516	1.54e-287	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIKBCBBA_01517	3.57e-89	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIKBCBBA_01518	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NIKBCBBA_01519	2.92e-187	ylmH	-	-	S	-	-	-	S4 domain protein
NIKBCBBA_01520	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NIKBCBBA_01521	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIKBCBBA_01522	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NIKBCBBA_01523	7.12e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NIKBCBBA_01524	3.76e-22	-	-	-	-	-	-	-	-
NIKBCBBA_01525	2.8e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIKBCBBA_01526	8.66e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NIKBCBBA_01527	3.92e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NIKBCBBA_01528	1.46e-274	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIKBCBBA_01529	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NIKBCBBA_01530	5.21e-155	-	-	-	S	-	-	-	repeat protein
NIKBCBBA_01531	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIKBCBBA_01532	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIKBCBBA_01533	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NIKBCBBA_01534	4.51e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIKBCBBA_01535	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NIKBCBBA_01536	7.15e-315	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIKBCBBA_01537	3.59e-109	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIKBCBBA_01538	7.15e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIKBCBBA_01539	1.88e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIKBCBBA_01540	9e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIKBCBBA_01541	1.81e-273	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIKBCBBA_01542	5e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIKBCBBA_01543	4e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NIKBCBBA_01544	2.15e-75	-	-	-	-	-	-	-	-
NIKBCBBA_01546	9.61e-208	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NIKBCBBA_01547	4.37e-39	-	-	-	-	-	-	-	-
NIKBCBBA_01548	1.57e-234	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
NIKBCBBA_01549	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NIKBCBBA_01550	3.13e-104	-	-	-	-	-	-	-	-
NIKBCBBA_01551	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIKBCBBA_01552	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NIKBCBBA_01553	1.9e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NIKBCBBA_01554	6.1e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIKBCBBA_01555	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NIKBCBBA_01556	2.02e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NIKBCBBA_01557	8.57e-170	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NIKBCBBA_01558	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NIKBCBBA_01559	1.85e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NIKBCBBA_01560	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NIKBCBBA_01561	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NIKBCBBA_01562	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIKBCBBA_01563	1.49e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NIKBCBBA_01564	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_01565	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIKBCBBA_01566	1.16e-249	-	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_01567	1.66e-111	ymdB	-	-	S	-	-	-	Macro domain protein
NIKBCBBA_01568	4.38e-81	-	-	-	K	-	-	-	Helix-turn-helix domain
NIKBCBBA_01570	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NIKBCBBA_01571	4.95e-63	-	-	-	-	-	-	-	-
NIKBCBBA_01572	1.11e-299	-	-	-	S	-	-	-	Putative metallopeptidase domain
NIKBCBBA_01573	3.73e-264	-	-	-	S	-	-	-	associated with various cellular activities
NIKBCBBA_01574	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NIKBCBBA_01575	4.92e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NIKBCBBA_01577	8.88e-147	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NIKBCBBA_01578	9.52e-72	-	-	-	-	-	-	-	-
NIKBCBBA_01581	2.68e-179	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NIKBCBBA_01582	2.48e-66	-	-	-	-	-	-	-	-
NIKBCBBA_01586	5.65e-18	-	-	-	K	-	-	-	Helix-turn-helix domain
NIKBCBBA_01588	6.61e-256	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
NIKBCBBA_01589	3.82e-295	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NIKBCBBA_01590	4.33e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NIKBCBBA_01591	1.21e-136	-	-	-	NU	-	-	-	mannosyl-glycoprotein
NIKBCBBA_01592	2.89e-177	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NIKBCBBA_01593	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NIKBCBBA_01594	2.3e-128	-	-	-	K	-	-	-	Helix-turn-helix domain
NIKBCBBA_01595	5.93e-61	-	-	-	-	-	-	-	-
NIKBCBBA_01596	1.09e-42	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NIKBCBBA_01597	1.88e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
NIKBCBBA_01599	5.61e-144	-	-	-	M	-	-	-	PFAM NLP P60 protein
NIKBCBBA_01600	1.5e-231	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NIKBCBBA_01601	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NIKBCBBA_01602	3.26e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01603	4.74e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
NIKBCBBA_01604	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NIKBCBBA_01605	2.95e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NIKBCBBA_01606	4.21e-87	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NIKBCBBA_01607	9.96e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NIKBCBBA_01608	1.26e-167	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NIKBCBBA_01609	5.09e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NIKBCBBA_01610	3.34e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NIKBCBBA_01611	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIKBCBBA_01612	2.43e-300	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NIKBCBBA_01613	1.63e-314	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NIKBCBBA_01614	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NIKBCBBA_01615	2.33e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NIKBCBBA_01616	9.86e-54	-	-	-	-	-	-	-	-
NIKBCBBA_01617	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIKBCBBA_01618	1.35e-262	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
NIKBCBBA_01619	2.48e-163	-	-	-	S	-	-	-	Alpha beta hydrolase
NIKBCBBA_01620	1.39e-277	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NIKBCBBA_01621	3.7e-120	-	-	-	-	-	-	-	-
NIKBCBBA_01623	2.32e-158	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NIKBCBBA_01624	2.67e-21	-	-	-	-	-	-	-	-
NIKBCBBA_01625	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NIKBCBBA_01626	1.18e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NIKBCBBA_01627	1.48e-114	-	-	-	-	-	-	-	-
NIKBCBBA_01628	7.97e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NIKBCBBA_01629	5.82e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
NIKBCBBA_01630	4.02e-144	-	-	-	-	-	-	-	-
NIKBCBBA_01631	2.6e-33	-	-	-	-	-	-	-	-
NIKBCBBA_01632	6.27e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIKBCBBA_01633	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIKBCBBA_01634	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NIKBCBBA_01635	9.36e-48	-	-	-	-	-	-	-	-
NIKBCBBA_01636	1.92e-111	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NIKBCBBA_01637	1.13e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
NIKBCBBA_01638	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NIKBCBBA_01639	1.94e-134	-	-	-	I	-	-	-	Acid phosphatase homologues
NIKBCBBA_01640	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIKBCBBA_01641	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
NIKBCBBA_01642	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NIKBCBBA_01643	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NIKBCBBA_01644	6.61e-179	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NIKBCBBA_01645	1.95e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NIKBCBBA_01646	1.39e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIKBCBBA_01647	1.44e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NIKBCBBA_01648	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIKBCBBA_01649	2.97e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NIKBCBBA_01650	1.21e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIKBCBBA_01651	2.13e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIKBCBBA_01652	3.37e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NIKBCBBA_01653	9.45e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NIKBCBBA_01654	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIKBCBBA_01655	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIKBCBBA_01656	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NIKBCBBA_01657	5.86e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NIKBCBBA_01658	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NIKBCBBA_01659	3.25e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
NIKBCBBA_01660	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIKBCBBA_01661	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIKBCBBA_01662	5.31e-210	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIKBCBBA_01663	1.22e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NIKBCBBA_01664	6e-83	-	-	-	-	-	-	-	-
NIKBCBBA_01665	1.6e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIKBCBBA_01666	5.7e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIKBCBBA_01667	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NIKBCBBA_01668	7.36e-272	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIKBCBBA_01669	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIKBCBBA_01670	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NIKBCBBA_01671	9.31e-251	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NIKBCBBA_01673	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NIKBCBBA_01675	3.36e-77	-	-	-	-	-	-	-	-
NIKBCBBA_01676	1.62e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NIKBCBBA_01677	8.84e-161	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIKBCBBA_01678	5.61e-71	-	-	-	-	-	-	-	-
NIKBCBBA_01679	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIKBCBBA_01680	1.54e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIKBCBBA_01681	3.34e-208	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NIKBCBBA_01682	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NIKBCBBA_01683	2.88e-166	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01684	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NIKBCBBA_01685	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NIKBCBBA_01686	1.35e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NIKBCBBA_01687	3.87e-215	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIKBCBBA_01688	4.88e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIKBCBBA_01689	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NIKBCBBA_01690	3.13e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NIKBCBBA_01691	2.05e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIKBCBBA_01692	9.08e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NIKBCBBA_01693	5.2e-108	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIKBCBBA_01694	4.09e-78	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NIKBCBBA_01695	3.78e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIKBCBBA_01696	1.19e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NIKBCBBA_01697	4.33e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NIKBCBBA_01698	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NIKBCBBA_01699	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIKBCBBA_01700	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIKBCBBA_01701	4.16e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NIKBCBBA_01702	1.88e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NIKBCBBA_01703	1.91e-194	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIKBCBBA_01704	5.91e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NIKBCBBA_01705	4.6e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NIKBCBBA_01706	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NIKBCBBA_01707	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NIKBCBBA_01708	5.36e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NIKBCBBA_01709	6.73e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NIKBCBBA_01710	2.05e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIKBCBBA_01711	1.6e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIKBCBBA_01712	2.72e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIKBCBBA_01713	4.11e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NIKBCBBA_01714	6e-130	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIKBCBBA_01715	6.42e-238	-	-	-	S	-	-	-	Helix-turn-helix domain
NIKBCBBA_01716	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NIKBCBBA_01717	1.76e-82	-	-	-	M	-	-	-	Lysin motif
NIKBCBBA_01718	4.96e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NIKBCBBA_01719	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NIKBCBBA_01720	1.9e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NIKBCBBA_01721	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIKBCBBA_01722	3.7e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NIKBCBBA_01723	5.06e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIKBCBBA_01724	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NIKBCBBA_01725	5.75e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIKBCBBA_01726	9.31e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIKBCBBA_01727	3.02e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NIKBCBBA_01728	2.05e-192	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NIKBCBBA_01729	5.75e-213	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NIKBCBBA_01730	1.36e-139	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NIKBCBBA_01731	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NIKBCBBA_01732	5.48e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIKBCBBA_01733	1.27e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIKBCBBA_01734	2.41e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NIKBCBBA_01735	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIKBCBBA_01736	1.12e-211	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NIKBCBBA_01737	2.04e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIKBCBBA_01738	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIKBCBBA_01739	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIKBCBBA_01740	1.76e-104	-	-	-	F	-	-	-	NUDIX domain
NIKBCBBA_01741	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NIKBCBBA_01742	1.68e-85	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NIKBCBBA_01743	3.19e-66	-	-	-	-	-	-	-	-
NIKBCBBA_01745	1.6e-109	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NIKBCBBA_01746	9.07e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NIKBCBBA_01747	8.86e-35	-	-	-	-	-	-	-	-
NIKBCBBA_01748	4.45e-122	-	-	-	-	-	-	-	-
NIKBCBBA_01749	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NIKBCBBA_01750	3.78e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
NIKBCBBA_01751	1.55e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NIKBCBBA_01752	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NIKBCBBA_01753	4.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIKBCBBA_01754	3.8e-63	-	-	-	-	-	-	-	-
NIKBCBBA_01755	6.1e-40	-	-	-	-	-	-	-	-
NIKBCBBA_01756	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NIKBCBBA_01757	3.61e-60	-	-	-	-	-	-	-	-
NIKBCBBA_01758	1.03e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NIKBCBBA_01759	1.32e-218	-	-	-	S	-	-	-	Protein of unknown function DUF262
NIKBCBBA_01760	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NIKBCBBA_01761	1.4e-80	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NIKBCBBA_01762	7.76e-38	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
NIKBCBBA_01763	9.34e-227	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIKBCBBA_01764	7.1e-126	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NIKBCBBA_01765	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NIKBCBBA_01766	1.34e-42	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
NIKBCBBA_01768	3.95e-225	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
NIKBCBBA_01769	4.27e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
NIKBCBBA_01770	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NIKBCBBA_01771	1.63e-260	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NIKBCBBA_01772	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
NIKBCBBA_01773	3.08e-81	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NIKBCBBA_01774	2e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NIKBCBBA_01775	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NIKBCBBA_01776	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NIKBCBBA_01777	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
NIKBCBBA_01778	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NIKBCBBA_01779	2.07e-299	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NIKBCBBA_01780	7.99e-293	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIKBCBBA_01781	8.76e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NIKBCBBA_01782	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NIKBCBBA_01783	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NIKBCBBA_01784	7.79e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NIKBCBBA_01785	2.91e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NIKBCBBA_01786	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
NIKBCBBA_01787	9.84e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NIKBCBBA_01788	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NIKBCBBA_01789	1.48e-189	-	-	-	O	-	-	-	Band 7 protein
NIKBCBBA_01790	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
NIKBCBBA_01791	4.24e-162	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
NIKBCBBA_01792	7.45e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
NIKBCBBA_01793	1.78e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
NIKBCBBA_01794	1.38e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NIKBCBBA_01795	7.04e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NIKBCBBA_01796	5.26e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
NIKBCBBA_01797	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NIKBCBBA_01798	1.61e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NIKBCBBA_01799	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIKBCBBA_01800	1.6e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NIKBCBBA_01801	4.5e-213	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NIKBCBBA_01802	5.52e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NIKBCBBA_01803	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NIKBCBBA_01804	5.48e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NIKBCBBA_01805	5.6e-158	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NIKBCBBA_01806	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
NIKBCBBA_01807	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NIKBCBBA_01808	4.93e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIKBCBBA_01809	2.86e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NIKBCBBA_01810	5.39e-71	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIKBCBBA_01811	3.97e-107	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NIKBCBBA_01812	1.2e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NIKBCBBA_01813	4.44e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NIKBCBBA_01814	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NIKBCBBA_01815	1.41e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIKBCBBA_01816	2.19e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NIKBCBBA_01817	3.88e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NIKBCBBA_01818	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NIKBCBBA_01819	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NIKBCBBA_01820	8.47e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
NIKBCBBA_01821	1.19e-124	-	-	-	-	-	-	-	-
NIKBCBBA_01822	9.78e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NIKBCBBA_01823	4.01e-200	gspA	-	-	M	-	-	-	family 8
NIKBCBBA_01824	5.74e-204	-	-	-	S	-	-	-	Alpha beta hydrolase
NIKBCBBA_01825	9.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NIKBCBBA_01826	4.98e-307	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NIKBCBBA_01827	4.16e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NIKBCBBA_01828	1.25e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
NIKBCBBA_01829	1.29e-202	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
NIKBCBBA_01830	4.13e-109	-	-	-	C	-	-	-	Flavodoxin
NIKBCBBA_01831	1.19e-103	-	-	-	S	-	-	-	Cupin domain
NIKBCBBA_01832	1.92e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
NIKBCBBA_01833	1.6e-306	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NIKBCBBA_01834	9.74e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NIKBCBBA_01835	5.47e-314	yhdP	-	-	S	-	-	-	Transporter associated domain
NIKBCBBA_01836	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NIKBCBBA_01837	8.48e-176	-	-	-	S	-	-	-	DUF218 domain
NIKBCBBA_01838	1.14e-88	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIKBCBBA_01839	4.02e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIKBCBBA_01840	8.58e-71	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIKBCBBA_01841	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
NIKBCBBA_01842	1.18e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
NIKBCBBA_01843	1.44e-293	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NIKBCBBA_01844	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIKBCBBA_01846	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NIKBCBBA_01847	2.32e-200	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NIKBCBBA_01848	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIKBCBBA_01849	6.6e-53	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NIKBCBBA_01850	8.85e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NIKBCBBA_01851	2.41e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NIKBCBBA_01852	1.3e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NIKBCBBA_01853	2.82e-26	-	-	-	-	-	-	-	-
NIKBCBBA_01854	5.63e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
NIKBCBBA_01855	2.44e-186	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NIKBCBBA_01856	8.85e-61	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NIKBCBBA_01858	3.57e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NIKBCBBA_01859	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
NIKBCBBA_01860	5.25e-72	-	-	-	-	-	-	-	-
NIKBCBBA_01861	2.39e-116	-	-	-	L	-	-	-	Transposase
NIKBCBBA_01862	2.03e-76	isp	-	-	L	-	-	-	Transposase
NIKBCBBA_01871	2.75e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NIKBCBBA_01872	7.35e-175	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NIKBCBBA_01873	5.91e-184	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIKBCBBA_01874	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NIKBCBBA_01875	3.25e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIKBCBBA_01876	5.1e-97	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIKBCBBA_01877	6.71e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIKBCBBA_01878	1.94e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NIKBCBBA_01879	5.61e-203	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NIKBCBBA_01880	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIKBCBBA_01881	1.59e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIKBCBBA_01882	3.34e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NIKBCBBA_01883	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIKBCBBA_01885	2.58e-253	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NIKBCBBA_01886	7.42e-310	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
NIKBCBBA_01887	4.89e-202	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NIKBCBBA_01888	1.15e-152	-	-	-	L	-	-	-	Integrase
NIKBCBBA_01889	2.25e-188	-	-	-	EG	-	-	-	EamA-like transporter family
NIKBCBBA_01890	1.51e-164	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
NIKBCBBA_01891	9.16e-125	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
NIKBCBBA_01892	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NIKBCBBA_01893	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIKBCBBA_01894	6.03e-226	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
NIKBCBBA_01895	2.07e-101	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
NIKBCBBA_01896	1.25e-281	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
NIKBCBBA_01897	7.54e-96	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
NIKBCBBA_01898	5.1e-121	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NIKBCBBA_01899	1.29e-59	-	-	-	-	-	-	-	-
NIKBCBBA_01900	5.42e-233	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
NIKBCBBA_01901	7.15e-148	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NIKBCBBA_01902	2.19e-26	-	-	-	-	-	-	-	-
NIKBCBBA_01903	3.34e-219	-	-	-	-	-	-	-	-
NIKBCBBA_01904	1.81e-183	-	-	-	H	-	-	-	geranyltranstransferase activity
NIKBCBBA_01905	1.76e-277	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
NIKBCBBA_01906	1.04e-41	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
NIKBCBBA_01907	1.81e-81	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
NIKBCBBA_01908	9.54e-97	-	-	-	S	-	-	-	Flavodoxin
NIKBCBBA_01909	3.83e-164	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIKBCBBA_01910	4.18e-165	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NIKBCBBA_01911	2.35e-223	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NIKBCBBA_01912	1.03e-216	-	-	-	-	-	-	-	-
NIKBCBBA_01913	4.26e-98	-	-	-	-	-	-	-	-
NIKBCBBA_01914	1.1e-153	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NIKBCBBA_01915	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
NIKBCBBA_01916	4.3e-68	-	-	-	-	-	-	-	-
NIKBCBBA_01917	1.53e-177	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIKBCBBA_01918	1.75e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NIKBCBBA_01919	1.34e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIKBCBBA_01920	1.96e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein