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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
GKNPKEJL_00001	7.28e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKNPKEJL_00002	8.37e-14	-	-	-	T	-	-	-	SpoVT / AbrB like domain
GKNPKEJL_00003	2.61e-235	-	-	-	M	-	-	-	lysozyme activity
GKNPKEJL_00007	0.0	-	-	-	LM	-	-	-	gp58-like protein
GKNPKEJL_00008	1.1e-69	-	-	-	-	-	-	-	-
GKNPKEJL_00009	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
GKNPKEJL_00010	9.13e-44	-	-	-	-	-	-	-	-
GKNPKEJL_00011	3.28e-75	-	-	-	-	-	-	-	-
GKNPKEJL_00012	3.23e-94	-	-	-	S	-	-	-	Phage tail tube protein, TTP
GKNPKEJL_00013	4.15e-58	-	-	-	-	-	-	-	-
GKNPKEJL_00014	7.4e-101	-	-	-	-	-	-	-	-
GKNPKEJL_00015	9.81e-77	-	-	-	-	-	-	-	-
GKNPKEJL_00016	2.82e-47	-	-	-	-	-	-	-	-
GKNPKEJL_00017	8.56e-215	-	-	-	S	-	-	-	Phage major capsid protein E
GKNPKEJL_00018	1.8e-72	-	-	-	-	-	-	-	-
GKNPKEJL_00019	2.62e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
GKNPKEJL_00020	7.62e-192	-	-	-	S	-	-	-	Phage Mu protein F like protein
GKNPKEJL_00021	5.97e-274	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
GKNPKEJL_00022	5.18e-275	-	-	-	S	-	-	-	Terminase-like family
GKNPKEJL_00023	3.82e-163	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
GKNPKEJL_00026	3.71e-87	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
GKNPKEJL_00027	1.15e-09	-	-	-	-	-	-	-	-
GKNPKEJL_00035	4.07e-80	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
GKNPKEJL_00036	2.01e-22	-	-	-	-	-	-	-	-
GKNPKEJL_00042	5.91e-65	-	-	-	S	-	-	-	ORF6C domain
GKNPKEJL_00045	2.05e-72	-	-	-	-	-	-	-	-
GKNPKEJL_00046	2.27e-171	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
GKNPKEJL_00047	5.48e-71	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
GKNPKEJL_00048	3.52e-101	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
GKNPKEJL_00059	1.14e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
GKNPKEJL_00062	6.41e-26	-	-	-	-	-	-	-	-
GKNPKEJL_00063	8.3e-10	-	-	-	-	-	-	-	-
GKNPKEJL_00067	7.96e-35	-	-	-	K	-	-	-	Helix-turn-helix domain
GKNPKEJL_00068	1.66e-92	-	-	-	S	-	-	-	IrrE N-terminal-like domain
GKNPKEJL_00069	1.55e-10	-	-	-	-	-	-	-	-
GKNPKEJL_00073	3.42e-52	-	-	-	-	-	-	-	-
GKNPKEJL_00074	7.59e-64	-	-	-	-	-	-	-	-
GKNPKEJL_00075	3.91e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GKNPKEJL_00076	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKNPKEJL_00077	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
GKNPKEJL_00078	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
GKNPKEJL_00079	7.57e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKNPKEJL_00080	2.17e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
GKNPKEJL_00081	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
GKNPKEJL_00082	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKNPKEJL_00083	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKNPKEJL_00084	4.94e-285	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKNPKEJL_00085	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
GKNPKEJL_00086	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKNPKEJL_00087	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKNPKEJL_00088	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKNPKEJL_00089	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKNPKEJL_00090	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
GKNPKEJL_00091	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GKNPKEJL_00092	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
GKNPKEJL_00093	1.91e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
GKNPKEJL_00094	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
GKNPKEJL_00095	3.75e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKNPKEJL_00096	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GKNPKEJL_00097	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
GKNPKEJL_00098	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKNPKEJL_00099	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKNPKEJL_00100	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKNPKEJL_00101	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKNPKEJL_00102	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKNPKEJL_00103	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
GKNPKEJL_00104	9e-72	-	-	-	-	-	-	-	-
GKNPKEJL_00105	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
GKNPKEJL_00106	1.25e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GKNPKEJL_00107	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
GKNPKEJL_00108	8.12e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GKNPKEJL_00109	3.31e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKNPKEJL_00110	1.27e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKNPKEJL_00111	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKNPKEJL_00112	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKNPKEJL_00113	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
GKNPKEJL_00114	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
GKNPKEJL_00115	1.06e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GKNPKEJL_00116	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKNPKEJL_00117	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
GKNPKEJL_00118	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
GKNPKEJL_00119	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
GKNPKEJL_00120	7.77e-144	-	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_00124	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
GKNPKEJL_00125	1.47e-223	-	-	-	-	-	-	-	-
GKNPKEJL_00126	4.87e-203	-	-	-	-	-	-	-	-
GKNPKEJL_00127	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GKNPKEJL_00128	1.99e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKNPKEJL_00147	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GKNPKEJL_00150	1.03e-37	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GKNPKEJL_00151	2.68e-73	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GKNPKEJL_00152	1.22e-271	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
GKNPKEJL_00154	6.6e-69	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
GKNPKEJL_00155	2.57e-118	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
GKNPKEJL_00156	6.65e-97	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
GKNPKEJL_00157	1.19e-93	-	-	-	M	-	-	-	Glycosyltransferase like family 2
GKNPKEJL_00158	1.56e-64	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
GKNPKEJL_00159	1.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
GKNPKEJL_00160	1.23e-194	epsB	-	-	M	-	-	-	biosynthesis protein
GKNPKEJL_00161	2.73e-219	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GKNPKEJL_00162	1.37e-90	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GKNPKEJL_00163	9.11e-123	-	-	-	-	-	-	-	-
GKNPKEJL_00164	1.08e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GKNPKEJL_00165	2.12e-86	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GKNPKEJL_00166	7.59e-37	-	-	-	-	-	-	-	-
GKNPKEJL_00167	6.28e-136	-	-	-	K	-	-	-	DNA-templated transcription, initiation
GKNPKEJL_00168	4.1e-51	-	-	-	-	-	-	-	-
GKNPKEJL_00169	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKNPKEJL_00170	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
GKNPKEJL_00171	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GKNPKEJL_00173	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKNPKEJL_00174	1.27e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
GKNPKEJL_00175	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
GKNPKEJL_00176	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
GKNPKEJL_00177	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKNPKEJL_00178	7.52e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKNPKEJL_00179	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKNPKEJL_00180	2.37e-184	-	-	-	S	-	-	-	DUF218 domain
GKNPKEJL_00181	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
GKNPKEJL_00182	1.84e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
GKNPKEJL_00183	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
GKNPKEJL_00184	3.94e-307	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GKNPKEJL_00185	3.87e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
GKNPKEJL_00186	1.34e-100	-	-	-	S	-	-	-	Cupin domain
GKNPKEJL_00187	1.55e-104	-	-	-	C	-	-	-	Flavodoxin
GKNPKEJL_00188	7.32e-179	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
GKNPKEJL_00189	2.13e-189	yvgN	-	-	C	-	-	-	Aldo keto reductase
GKNPKEJL_00190	6.02e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKNPKEJL_00191	7.61e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GKNPKEJL_00192	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GKNPKEJL_00193	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GKNPKEJL_00194	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
GKNPKEJL_00195	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKNPKEJL_00196	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
GKNPKEJL_00197	2.23e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GKNPKEJL_00198	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
GKNPKEJL_00199	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKNPKEJL_00200	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
GKNPKEJL_00201	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKNPKEJL_00202	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKNPKEJL_00203	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKNPKEJL_00204	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKNPKEJL_00205	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
GKNPKEJL_00206	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKNPKEJL_00207	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKNPKEJL_00208	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
GKNPKEJL_00209	3.1e-168	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
GKNPKEJL_00210	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
GKNPKEJL_00211	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
GKNPKEJL_00212	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKNPKEJL_00214	2.91e-65	-	-	-	-	-	-	-	-
GKNPKEJL_00215	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKNPKEJL_00216	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKNPKEJL_00217	1.79e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKNPKEJL_00218	1.44e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
GKNPKEJL_00220	4.39e-287	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
GKNPKEJL_00221	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKNPKEJL_00222	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKNPKEJL_00223	4.47e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GKNPKEJL_00224	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKNPKEJL_00225	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GKNPKEJL_00226	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKNPKEJL_00227	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKNPKEJL_00228	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GKNPKEJL_00229	5.12e-266	yacL	-	-	S	-	-	-	domain protein
GKNPKEJL_00230	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKNPKEJL_00231	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
GKNPKEJL_00232	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
GKNPKEJL_00233	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKNPKEJL_00234	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GKNPKEJL_00235	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
GKNPKEJL_00236	5.84e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_00237	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKNPKEJL_00238	2.47e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GKNPKEJL_00239	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GKNPKEJL_00240	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKNPKEJL_00241	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GKNPKEJL_00242	6.41e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
GKNPKEJL_00243	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
GKNPKEJL_00245	5.75e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
GKNPKEJL_00246	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
GKNPKEJL_00247	6.42e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKNPKEJL_00248	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKNPKEJL_00249	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
GKNPKEJL_00250	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GKNPKEJL_00251	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
GKNPKEJL_00252	0.0	-	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_00253	5.92e-150	-	-	-	-	-	-	-	-
GKNPKEJL_00256	2.8e-173	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GKNPKEJL_00257	4.89e-19	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GKNPKEJL_00258	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
GKNPKEJL_00261	9.11e-114	-	-	-	C	-	-	-	Oxidoreductase
GKNPKEJL_00262	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
GKNPKEJL_00263	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
GKNPKEJL_00264	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
GKNPKEJL_00265	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
GKNPKEJL_00266	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKNPKEJL_00268	3.66e-286	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GKNPKEJL_00269	6.57e-129	-	-	-	S	-	-	-	Peptidase, M23
GKNPKEJL_00270	4.45e-70	-	-	-	M	-	-	-	Peptidase_C39 like family
GKNPKEJL_00272	1.01e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
GKNPKEJL_00273	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKNPKEJL_00274	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKNPKEJL_00275	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKNPKEJL_00276	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
GKNPKEJL_00277	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKNPKEJL_00278	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKNPKEJL_00279	1.79e-84	-	-	-	-	-	-	-	-
GKNPKEJL_00280	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKNPKEJL_00281	1.95e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
GKNPKEJL_00282	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GKNPKEJL_00283	9.8e-305	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GKNPKEJL_00284	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GKNPKEJL_00285	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
GKNPKEJL_00286	1.77e-56	-	-	-	-	-	-	-	-
GKNPKEJL_00287	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKNPKEJL_00288	2.84e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
GKNPKEJL_00289	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
GKNPKEJL_00290	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GKNPKEJL_00291	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKNPKEJL_00292	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
GKNPKEJL_00293	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
GKNPKEJL_00294	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKNPKEJL_00295	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
GKNPKEJL_00296	4.77e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
GKNPKEJL_00297	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
GKNPKEJL_00298	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
GKNPKEJL_00299	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GKNPKEJL_00300	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
GKNPKEJL_00301	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
GKNPKEJL_00302	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKNPKEJL_00303	1.23e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
GKNPKEJL_00304	3.4e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
GKNPKEJL_00305	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
GKNPKEJL_00306	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
GKNPKEJL_00307	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
GKNPKEJL_00308	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
GKNPKEJL_00309	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKNPKEJL_00310	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKNPKEJL_00311	1.03e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
GKNPKEJL_00312	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKNPKEJL_00313	2.26e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKNPKEJL_00314	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKNPKEJL_00315	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
GKNPKEJL_00316	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
GKNPKEJL_00317	2.44e-20	-	-	-	-	-	-	-	-
GKNPKEJL_00318	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKNPKEJL_00319	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKNPKEJL_00320	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKNPKEJL_00321	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
GKNPKEJL_00322	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
GKNPKEJL_00323	1.46e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKNPKEJL_00324	1.79e-121	-	-	-	-	-	-	-	-
GKNPKEJL_00325	6.03e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GKNPKEJL_00326	3.75e-06	-	-	-	L	-	-	-	GIY-YIG catalytic domain
GKNPKEJL_00327	1.48e-06	-	-	-	S	-	-	-	Helix-turn-helix domain
GKNPKEJL_00331	1.59e-50	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
GKNPKEJL_00332	1.78e-108	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
GKNPKEJL_00335	1.23e-36	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
GKNPKEJL_00336	1.16e-28	terS	-	-	L	-	-	-	Phage terminase, small subunit
GKNPKEJL_00337	3.9e-253	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
GKNPKEJL_00338	7.25e-177	-	-	-	S	-	-	-	Phage portal protein
GKNPKEJL_00339	8.21e-317	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
GKNPKEJL_00340	2.49e-25	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
GKNPKEJL_00343	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKNPKEJL_00344	6.77e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
GKNPKEJL_00345	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKNPKEJL_00346	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
GKNPKEJL_00347	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
GKNPKEJL_00348	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
GKNPKEJL_00349	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
GKNPKEJL_00350	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
GKNPKEJL_00351	1.02e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKNPKEJL_00352	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
GKNPKEJL_00353	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKNPKEJL_00354	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
GKNPKEJL_00355	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKNPKEJL_00356	1.83e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKNPKEJL_00357	1.18e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
GKNPKEJL_00358	5.46e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
GKNPKEJL_00359	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKNPKEJL_00360	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKNPKEJL_00361	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
GKNPKEJL_00362	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
GKNPKEJL_00363	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
GKNPKEJL_00364	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
GKNPKEJL_00365	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKNPKEJL_00366	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKNPKEJL_00367	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKNPKEJL_00368	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GKNPKEJL_00371	8.63e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GKNPKEJL_00372	2.5e-171	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
GKNPKEJL_00373	8.12e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GKNPKEJL_00374	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
GKNPKEJL_00375	2.03e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
GKNPKEJL_00376	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKNPKEJL_00377	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
GKNPKEJL_00378	1.05e-193	-	-	-	-	-	-	-	-
GKNPKEJL_00379	6.56e-54	-	-	-	M	-	-	-	Glycosyl transferase
GKNPKEJL_00380	6.21e-231	-	-	-	M	-	-	-	Glycosyl transferase
GKNPKEJL_00381	1.29e-279	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
GKNPKEJL_00382	7.72e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
GKNPKEJL_00383	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GKNPKEJL_00384	3.91e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
GKNPKEJL_00385	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
GKNPKEJL_00386	2.66e-114	-	-	-	Q	-	-	-	Methyltransferase
GKNPKEJL_00387	1.48e-290	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GKNPKEJL_00388	4.53e-103	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
GKNPKEJL_00389	7.95e-87	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
GKNPKEJL_00390	6.24e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GKNPKEJL_00391	1.83e-124	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GKNPKEJL_00392	6.93e-296	-	-	-	G	ko:K03832	-	ko00000,ko02000	Belongs to the glycosyl hydrolase family 6
GKNPKEJL_00393	1.18e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
GKNPKEJL_00394	3.04e-173	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GKNPKEJL_00395	1.97e-69	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
GKNPKEJL_00396	5.91e-105	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
GKNPKEJL_00397	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
GKNPKEJL_00399	4.75e-132	-	-	-	-	-	-	-	-
GKNPKEJL_00400	7.01e-109	-	-	-	-	-	-	-	-
GKNPKEJL_00401	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
GKNPKEJL_00402	5.28e-181	-	-	-	T	-	-	-	EAL domain
GKNPKEJL_00403	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
GKNPKEJL_00404	1.74e-85	-	-	-	-	-	-	-	-
GKNPKEJL_00405	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
GKNPKEJL_00406	3.43e-110	-	-	-	S	-	-	-	membrane
GKNPKEJL_00407	1.47e-104	-	-	-	S	-	-	-	membrane
GKNPKEJL_00408	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
GKNPKEJL_00409	1.14e-149	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
GKNPKEJL_00410	6.58e-36	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
GKNPKEJL_00411	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_00412	5.61e-75	-	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_00413	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
GKNPKEJL_00414	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
GKNPKEJL_00415	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
GKNPKEJL_00416	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
GKNPKEJL_00417	2.49e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
GKNPKEJL_00418	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
GKNPKEJL_00419	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
GKNPKEJL_00420	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GKNPKEJL_00421	2.15e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_00422	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
GKNPKEJL_00423	1.94e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
GKNPKEJL_00424	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GKNPKEJL_00425	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKNPKEJL_00426	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKNPKEJL_00427	1.16e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
GKNPKEJL_00428	3.51e-89	-	-	-	P	-	-	-	FAD-binding domain
GKNPKEJL_00429	7.62e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GKNPKEJL_00430	1.66e-303	-	-	-	T	-	-	-	GHKL domain
GKNPKEJL_00431	2.05e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
GKNPKEJL_00432	6.74e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GKNPKEJL_00433	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
GKNPKEJL_00434	1.15e-178	-	-	-	-	-	-	-	-
GKNPKEJL_00435	3.28e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
GKNPKEJL_00436	4.4e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GKNPKEJL_00437	1.84e-75	-	-	-	-	-	-	-	-
GKNPKEJL_00438	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKNPKEJL_00439	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
GKNPKEJL_00440	9.06e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GKNPKEJL_00441	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
GKNPKEJL_00442	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
GKNPKEJL_00443	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKNPKEJL_00444	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
GKNPKEJL_00445	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
GKNPKEJL_00446	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GKNPKEJL_00447	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKNPKEJL_00448	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
GKNPKEJL_00449	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
GKNPKEJL_00450	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKNPKEJL_00451	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
GKNPKEJL_00452	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKNPKEJL_00453	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKNPKEJL_00454	1.02e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
GKNPKEJL_00455	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GKNPKEJL_00456	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GKNPKEJL_00457	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKNPKEJL_00458	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKNPKEJL_00459	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKNPKEJL_00460	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKNPKEJL_00461	2.66e-275	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
GKNPKEJL_00465	5.08e-49	-	-	-	L	-	-	-	Integrase core domain
GKNPKEJL_00468	1.76e-143	-	-	-	F	-	-	-	NUDIX domain
GKNPKEJL_00469	1.5e-289	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKNPKEJL_00470	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
GKNPKEJL_00471	1.65e-83	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
GKNPKEJL_00472	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
GKNPKEJL_00474	1.76e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
GKNPKEJL_00475	5.11e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GKNPKEJL_00476	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
GKNPKEJL_00477	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
GKNPKEJL_00478	1.33e-121	-	-	-	S	-	-	-	PFAM Archaeal ATPase
GKNPKEJL_00479	3.81e-62	-	-	-	-	-	-	-	-
GKNPKEJL_00481	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKNPKEJL_00482	1.52e-205	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
GKNPKEJL_00483	2.64e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
GKNPKEJL_00484	1.16e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
GKNPKEJL_00485	7.41e-120	-	-	-	-	-	-	-	-
GKNPKEJL_00486	1.77e-157	pnb	-	-	C	-	-	-	nitroreductase
GKNPKEJL_00487	5.68e-95	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
GKNPKEJL_00488	4.76e-217	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
GKNPKEJL_00489	1.31e-213	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
GKNPKEJL_00490	1.53e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GKNPKEJL_00491	1.74e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
GKNPKEJL_00492	1.2e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GKNPKEJL_00493	5.18e-27	-	-	-	-	-	-	-	-
GKNPKEJL_00494	8.83e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GKNPKEJL_00495	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
GKNPKEJL_00496	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
GKNPKEJL_00497	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
GKNPKEJL_00498	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GKNPKEJL_00499	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
GKNPKEJL_00500	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
GKNPKEJL_00501	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
GKNPKEJL_00502	7.43e-295	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
GKNPKEJL_00504	8.5e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKNPKEJL_00505	2.02e-72	-	-	-	-	-	-	-	-
GKNPKEJL_00506	3.41e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GKNPKEJL_00507	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GKNPKEJL_00508	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKNPKEJL_00509	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GKNPKEJL_00510	5.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GKNPKEJL_00511	3.21e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
GKNPKEJL_00512	3.49e-48	-	-	-	-	-	-	-	-
GKNPKEJL_00513	4.33e-69	-	-	-	-	-	-	-	-
GKNPKEJL_00514	2.61e-260	-	-	-	-	-	-	-	-
GKNPKEJL_00515	1.59e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKNPKEJL_00516	8.01e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GKNPKEJL_00517	6.94e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
GKNPKEJL_00518	3.56e-160	XK27_10500	-	-	K	-	-	-	response regulator
GKNPKEJL_00519	2.4e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
GKNPKEJL_00520	9.68e-172	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_00521	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
GKNPKEJL_00522	9.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
GKNPKEJL_00523	7.55e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GKNPKEJL_00524	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKNPKEJL_00525	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_00526	1.42e-111	ymdB	-	-	S	-	-	-	Macro domain protein
GKNPKEJL_00527	8.68e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
GKNPKEJL_00528	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GKNPKEJL_00529	2.45e-63	-	-	-	-	-	-	-	-
GKNPKEJL_00530	1.47e-304	-	-	-	S	-	-	-	Putative metallopeptidase domain
GKNPKEJL_00531	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
GKNPKEJL_00532	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
GKNPKEJL_00533	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
GKNPKEJL_00534	1.24e-65	-	-	-	-	-	-	-	-
GKNPKEJL_00536	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
GKNPKEJL_00537	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKNPKEJL_00538	3.28e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKNPKEJL_00539	1.98e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
GKNPKEJL_00540	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKNPKEJL_00541	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
GKNPKEJL_00542	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
GKNPKEJL_00543	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKNPKEJL_00544	1.13e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GKNPKEJL_00545	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
GKNPKEJL_00546	5.97e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
GKNPKEJL_00547	6.76e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKNPKEJL_00548	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
GKNPKEJL_00549	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GKNPKEJL_00550	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKNPKEJL_00551	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
GKNPKEJL_00553	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
GKNPKEJL_00554	1.61e-54	-	-	-	-	-	-	-	-
GKNPKEJL_00555	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
GKNPKEJL_00556	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
GKNPKEJL_00557	2.49e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
GKNPKEJL_00558	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
GKNPKEJL_00559	5.36e-49	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GKNPKEJL_00560	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
GKNPKEJL_00561	1.98e-110	-	-	-	F	-	-	-	NUDIX domain
GKNPKEJL_00562	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKNPKEJL_00563	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKNPKEJL_00564	1.1e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKNPKEJL_00565	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
GKNPKEJL_00566	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKNPKEJL_00567	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
GKNPKEJL_00568	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKNPKEJL_00569	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKNPKEJL_00570	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
GKNPKEJL_00571	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
GKNPKEJL_00572	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
GKNPKEJL_00573	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
GKNPKEJL_00574	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
GKNPKEJL_00575	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKNPKEJL_00576	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKNPKEJL_00577	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_00578	4.94e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKNPKEJL_00579	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
GKNPKEJL_00580	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKNPKEJL_00581	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
GKNPKEJL_00582	1.73e-273	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
GKNPKEJL_00583	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
GKNPKEJL_00584	2.15e-83	-	-	-	M	-	-	-	Lysin motif
GKNPKEJL_00585	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
GKNPKEJL_00586	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
GKNPKEJL_00587	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKNPKEJL_00588	1.43e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GKNPKEJL_00589	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKNPKEJL_00590	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKNPKEJL_00591	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKNPKEJL_00592	2.74e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
GKNPKEJL_00593	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
GKNPKEJL_00594	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
GKNPKEJL_00595	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
GKNPKEJL_00596	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GKNPKEJL_00597	1.58e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GKNPKEJL_00598	1.25e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKNPKEJL_00599	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
GKNPKEJL_00600	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GKNPKEJL_00601	1.71e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKNPKEJL_00602	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKNPKEJL_00603	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
GKNPKEJL_00604	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
GKNPKEJL_00605	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
GKNPKEJL_00606	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKNPKEJL_00607	2.11e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
GKNPKEJL_00608	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKNPKEJL_00609	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
GKNPKEJL_00610	4.11e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GKNPKEJL_00611	5.1e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
GKNPKEJL_00612	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
GKNPKEJL_00613	4.26e-198	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKNPKEJL_00614	6.45e-49	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKNPKEJL_00615	3.43e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKNPKEJL_00617	3.3e-105	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GKNPKEJL_00618	6.64e-99	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GKNPKEJL_00619	7.38e-232	-	-	-	-	-	-	-	-
GKNPKEJL_00620	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKNPKEJL_00622	2.17e-99	-	-	-	S	-	-	-	Fic/DOC family
GKNPKEJL_00625	1.77e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GKNPKEJL_00626	2.69e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKNPKEJL_00627	1.98e-83	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
GKNPKEJL_00628	2.08e-145	-	-	-	S	-	-	-	Membrane
GKNPKEJL_00634	0.000773	-	-	-	S	-	-	-	YopX protein
GKNPKEJL_00646	2.57e-35	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
GKNPKEJL_00656	8.2e-92	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GKNPKEJL_00658	6e-39	-	-	-	-	-	-	-	-
GKNPKEJL_00659	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKNPKEJL_00660	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKNPKEJL_00661	3.03e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
GKNPKEJL_00662	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
GKNPKEJL_00663	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
GKNPKEJL_00664	1.67e-307	yhdP	-	-	S	-	-	-	Transporter associated domain
GKNPKEJL_00665	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
GKNPKEJL_00666	1.83e-113	-	-	-	GM	-	-	-	epimerase
GKNPKEJL_00667	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
GKNPKEJL_00668	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_00669	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
GKNPKEJL_00670	1.32e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
GKNPKEJL_00671	1.92e-202	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
GKNPKEJL_00672	1.51e-207	-	-	-	-	-	-	-	-
GKNPKEJL_00673	5.28e-225	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKNPKEJL_00674	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKNPKEJL_00675	3.91e-40	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKNPKEJL_00679	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
GKNPKEJL_00680	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
GKNPKEJL_00681	7.36e-179	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
GKNPKEJL_00682	2.26e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
GKNPKEJL_00683	1.26e-60	-	-	-	-	-	-	-	-
GKNPKEJL_00684	1.81e-41	-	-	-	-	-	-	-	-
GKNPKEJL_00685	1.09e-62	-	-	-	-	-	-	-	-
GKNPKEJL_00686	5.91e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKNPKEJL_00687	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GKNPKEJL_00688	5.36e-255	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
GKNPKEJL_00689	5.18e-15	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
GKNPKEJL_00690	3.99e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
GKNPKEJL_00691	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GKNPKEJL_00692	1.14e-124	-	-	-	-	-	-	-	-
GKNPKEJL_00693	3.09e-35	-	-	-	-	-	-	-	-
GKNPKEJL_00694	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GKNPKEJL_00695	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
GKNPKEJL_00697	9.14e-66	-	-	-	-	-	-	-	-
GKNPKEJL_00698	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
GKNPKEJL_00699	2.44e-72	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GKNPKEJL_00700	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GKNPKEJL_00701	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_00703	8.57e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
GKNPKEJL_00704	6.2e-271	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
GKNPKEJL_00705	1.82e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
GKNPKEJL_00706	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKNPKEJL_00708	4.77e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
GKNPKEJL_00709	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
GKNPKEJL_00710	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
GKNPKEJL_00711	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
GKNPKEJL_00712	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
GKNPKEJL_00713	2.14e-154	-	-	-	GM	-	-	-	NmrA-like family
GKNPKEJL_00714	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GKNPKEJL_00715	2.74e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
GKNPKEJL_00716	6.71e-102	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GKNPKEJL_00717	7.97e-292	-	-	-	-	-	-	-	-
GKNPKEJL_00718	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GKNPKEJL_00719	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GKNPKEJL_00720	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
GKNPKEJL_00721	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
GKNPKEJL_00722	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GKNPKEJL_00723	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
GKNPKEJL_00724	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
GKNPKEJL_00725	6.11e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
GKNPKEJL_00726	1.13e-259	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
GKNPKEJL_00728	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_00729	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_00730	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKNPKEJL_00731	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKNPKEJL_00732	3.82e-157	-	-	-	S	-	-	-	repeat protein
GKNPKEJL_00733	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
GKNPKEJL_00734	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKNPKEJL_00735	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
GKNPKEJL_00736	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GKNPKEJL_00737	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKNPKEJL_00738	1.54e-33	-	-	-	-	-	-	-	-
GKNPKEJL_00739	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
GKNPKEJL_00740	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GKNPKEJL_00741	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKNPKEJL_00742	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
GKNPKEJL_00743	1.97e-185	ylmH	-	-	S	-	-	-	S4 domain protein
GKNPKEJL_00744	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
GKNPKEJL_00745	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKNPKEJL_00746	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKNPKEJL_00747	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKNPKEJL_00748	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKNPKEJL_00749	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKNPKEJL_00750	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKNPKEJL_00751	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKNPKEJL_00752	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GKNPKEJL_00753	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
GKNPKEJL_00754	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKNPKEJL_00755	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
GKNPKEJL_00756	7.76e-74	-	-	-	-	-	-	-	-
GKNPKEJL_00757	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
GKNPKEJL_00758	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GKNPKEJL_00759	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKNPKEJL_00760	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
GKNPKEJL_00761	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
GKNPKEJL_00763	5.2e-198	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
GKNPKEJL_00764	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
GKNPKEJL_00765	3.24e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKNPKEJL_00766	6.83e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GKNPKEJL_00767	2.49e-43	-	-	-	-	-	-	-	-
GKNPKEJL_00768	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
GKNPKEJL_00771	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
GKNPKEJL_00772	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKNPKEJL_00773	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GKNPKEJL_00774	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
GKNPKEJL_00775	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
GKNPKEJL_00776	7.36e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
GKNPKEJL_00777	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKNPKEJL_00778	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
GKNPKEJL_00779	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKNPKEJL_00780	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
GKNPKEJL_00781	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
GKNPKEJL_00782	2.13e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
GKNPKEJL_00783	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GKNPKEJL_00784	1.51e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_00785	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GKNPKEJL_00786	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
GKNPKEJL_00787	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
GKNPKEJL_00788	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
GKNPKEJL_00789	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
GKNPKEJL_00790	1.23e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GKNPKEJL_00791	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GKNPKEJL_00792	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKNPKEJL_00793	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GKNPKEJL_00794	2.82e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
GKNPKEJL_00795	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
GKNPKEJL_00796	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKNPKEJL_00797	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKNPKEJL_00798	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GKNPKEJL_00799	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKNPKEJL_00800	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKNPKEJL_00801	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_00802	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_00803	7.47e-25	-	-	-	D	-	-	-	Glucan-binding protein C
GKNPKEJL_00804	5.77e-21	-	-	-	K	-	-	-	ORF6N domain
GKNPKEJL_00807	6.17e-13	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
GKNPKEJL_00808	5.68e-61	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
GKNPKEJL_00809	2.37e-179	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
GKNPKEJL_00812	1.08e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
GKNPKEJL_00817	2.88e-277	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
GKNPKEJL_00818	1.9e-72	-	-	-	-	-	-	-	-
GKNPKEJL_00820	4.26e-35	-	-	-	-	-	-	-	-
GKNPKEJL_00821	2.58e-239	-	-	-	U	-	-	-	type IV secretory pathway VirB4
GKNPKEJL_00823	1.79e-64	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GKNPKEJL_00826	0.000222	ydiL	-	-	S	ko:K07052	-	ko00000	protease
GKNPKEJL_00831	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GKNPKEJL_00832	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GKNPKEJL_00833	2.46e-113	-	-	-	-	-	-	-	-
GKNPKEJL_00834	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
GKNPKEJL_00835	4.99e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_00836	1.03e-146	-	-	-	-	-	-	-	-
GKNPKEJL_00837	2.14e-32	-	-	-	-	-	-	-	-
GKNPKEJL_00838	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
GKNPKEJL_00839	7.15e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKNPKEJL_00840	4.57e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
GKNPKEJL_00841	1.18e-50	-	-	-	-	-	-	-	-
GKNPKEJL_00842	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_00843	4.22e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_00844	2.39e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GKNPKEJL_00845	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
GKNPKEJL_00846	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
GKNPKEJL_00847	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GKNPKEJL_00848	1.89e-80	-	-	-	-	-	-	-	-
GKNPKEJL_00849	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKNPKEJL_00850	1.2e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_00851	2.72e-91	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKNPKEJL_00852	4e-82	-	-	-	S	-	-	-	integral membrane protein
GKNPKEJL_00853	1.54e-63	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
GKNPKEJL_00854	1.59e-27	-	-	-	-	-	-	-	-
GKNPKEJL_00855	2.63e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
GKNPKEJL_00856	2.12e-303	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GKNPKEJL_00857	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKNPKEJL_00858	2.65e-92	cps3I	-	-	G	-	-	-	Acyltransferase family
GKNPKEJL_00859	9.2e-43	-	-	-	-	-	-	-	-
GKNPKEJL_00860	8.31e-138	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
GKNPKEJL_00861	2.19e-36	-	-	-	M	-	-	-	Peptidase_C39 like family
GKNPKEJL_00862	3.11e-63	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GKNPKEJL_00863	2.79e-179	-	-	-	K	-	-	-	LysR substrate binding domain
GKNPKEJL_00864	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
GKNPKEJL_00865	4.45e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKNPKEJL_00866	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKNPKEJL_00867	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKNPKEJL_00868	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKNPKEJL_00869	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GKNPKEJL_00870	4.34e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKNPKEJL_00871	1.15e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
GKNPKEJL_00872	6.76e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
GKNPKEJL_00873	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
GKNPKEJL_00874	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GKNPKEJL_00875	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
GKNPKEJL_00876	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKNPKEJL_00877	2.66e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKNPKEJL_00878	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKNPKEJL_00879	2.13e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
GKNPKEJL_00880	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKNPKEJL_00881	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKNPKEJL_00882	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKNPKEJL_00883	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKNPKEJL_00884	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
GKNPKEJL_00885	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKNPKEJL_00886	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
GKNPKEJL_00887	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
GKNPKEJL_00888	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKNPKEJL_00889	4.31e-180	-	-	-	L	-	-	-	Bacterial dnaA protein
GKNPKEJL_00890	3.73e-74	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GKNPKEJL_00891	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GKNPKEJL_00892	5.36e-97	-	-	-	-	-	-	-	-
GKNPKEJL_00893	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GKNPKEJL_00894	3.42e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GKNPKEJL_00895	1.28e-18	-	-	-	-	-	-	-	-
GKNPKEJL_00896	8.1e-281	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GKNPKEJL_00897	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKNPKEJL_00898	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
GKNPKEJL_00899	7.13e-227	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKNPKEJL_00900	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
GKNPKEJL_00901	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
GKNPKEJL_00902	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
GKNPKEJL_00903	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
GKNPKEJL_00904	1.38e-59	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
GKNPKEJL_00905	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
GKNPKEJL_00906	2.68e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKNPKEJL_00907	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GKNPKEJL_00908	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GKNPKEJL_00909	0.0	-	-	-	S	-	-	-	membrane
GKNPKEJL_00910	1.33e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
GKNPKEJL_00911	3.11e-63	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GKNPKEJL_00913	1.99e-204	-	-	-	J	-	-	-	Methyltransferase
GKNPKEJL_00914	6.02e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
GKNPKEJL_00915	4.47e-229	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
GKNPKEJL_00917	0.0	-	-	-	L	-	-	-	PLD-like domain
GKNPKEJL_00918	2.93e-117	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
GKNPKEJL_00919	2.61e-211	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
GKNPKEJL_00920	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKNPKEJL_00921	2.95e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
GKNPKEJL_00922	2.94e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
GKNPKEJL_00923	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
GKNPKEJL_00924	3.61e-61	-	-	-	-	-	-	-	-
GKNPKEJL_00925	1.88e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GKNPKEJL_00926	4.1e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GKNPKEJL_00927	9.79e-29	-	-	-	-	-	-	-	-
GKNPKEJL_00928	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
GKNPKEJL_00929	4.16e-180	-	-	-	S	-	-	-	Membrane
GKNPKEJL_00930	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
GKNPKEJL_00931	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GKNPKEJL_00932	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKNPKEJL_00933	3.13e-192	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GKNPKEJL_00934	1.11e-89	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GKNPKEJL_00935	1.14e-170	-	-	-	L	-	-	-	Transposase
GKNPKEJL_00936	1.14e-170	-	-	-	L	-	-	-	Transposase
GKNPKEJL_00937	7.09e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKNPKEJL_00938	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
GKNPKEJL_00939	6.92e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
GKNPKEJL_00940	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKNPKEJL_00941	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKNPKEJL_00942	2.36e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GKNPKEJL_00943	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GKNPKEJL_00944	9.06e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKNPKEJL_00945	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
GKNPKEJL_00946	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKNPKEJL_00947	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKNPKEJL_00948	7.99e-293	-	-	-	V	-	-	-	MatE
GKNPKEJL_00949	0.0	potE	-	-	E	-	-	-	Amino Acid
GKNPKEJL_00950	1.14e-170	-	-	-	L	-	-	-	Transposase
GKNPKEJL_00951	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKNPKEJL_00952	4.26e-274	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
GKNPKEJL_00953	1.87e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
GKNPKEJL_00954	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKNPKEJL_00955	5.5e-235	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GKNPKEJL_00956	1.01e-63	-	-	-	K	-	-	-	LysR substrate binding domain
GKNPKEJL_00957	3.01e-229	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
GKNPKEJL_00958	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GKNPKEJL_00959	5.49e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GKNPKEJL_00960	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GKNPKEJL_00961	7.01e-60	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GKNPKEJL_00962	4.82e-238	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GKNPKEJL_00963	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GKNPKEJL_00964	0.0	-	-	-	M	-	-	-	domain protein
GKNPKEJL_00965	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
GKNPKEJL_00966	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GKNPKEJL_00967	4.94e-94	-	-	-	-	-	-	-	-
GKNPKEJL_00968	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
GKNPKEJL_00969	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
GKNPKEJL_00971	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKNPKEJL_00972	1.98e-118	-	-	-	-	-	-	-	-
GKNPKEJL_00973	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKNPKEJL_00974	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKNPKEJL_00975	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
GKNPKEJL_00976	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
GKNPKEJL_00977	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
GKNPKEJL_00978	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
GKNPKEJL_00979	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
GKNPKEJL_00980	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
GKNPKEJL_00981	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
GKNPKEJL_00982	2.33e-264	-	-	-	P	-	-	-	Voltage gated chloride channel
GKNPKEJL_00983	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
GKNPKEJL_00984	3.68e-152	dltr	-	-	K	-	-	-	response regulator
GKNPKEJL_00985	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
GKNPKEJL_00986	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GKNPKEJL_00987	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GKNPKEJL_00988	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GKNPKEJL_00989	1.99e-302	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
GKNPKEJL_00990	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKNPKEJL_00998	1.53e-305	isp	-	-	L	-	-	-	Transposase
GKNPKEJL_00999	4.99e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKNPKEJL_01000	5.79e-306	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
GKNPKEJL_01001	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
GKNPKEJL_01002	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKNPKEJL_01003	5.26e-203	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
GKNPKEJL_01004	3.31e-119	-	-	-	M	-	-	-	LysM domain protein
GKNPKEJL_01005	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
GKNPKEJL_01006	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
GKNPKEJL_01007	4.89e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GKNPKEJL_01008	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GKNPKEJL_01009	1.88e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
GKNPKEJL_01010	2.05e-193	yeaE	-	-	S	-	-	-	Aldo keto
GKNPKEJL_01011	3.66e-98	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GKNPKEJL_01012	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
GKNPKEJL_01013	2.27e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
GKNPKEJL_01014	2.91e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
GKNPKEJL_01015	7.03e-33	-	-	-	-	-	-	-	-
GKNPKEJL_01016	2.85e-134	-	-	-	V	-	-	-	VanZ like family
GKNPKEJL_01017	1.11e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GKNPKEJL_01018	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
GKNPKEJL_01019	0.0	-	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_01020	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
GKNPKEJL_01021	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKNPKEJL_01022	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
GKNPKEJL_01023	1.45e-55	-	-	-	-	-	-	-	-
GKNPKEJL_01024	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GKNPKEJL_01025	3.96e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKNPKEJL_01026	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
GKNPKEJL_01027	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GKNPKEJL_01028	3.17e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKNPKEJL_01029	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
GKNPKEJL_01030	3.08e-146	-	-	-	-	-	-	-	-
GKNPKEJL_01031	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
GKNPKEJL_01032	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKNPKEJL_01033	1.52e-43	-	-	-	-	-	-	-	-
GKNPKEJL_01034	4.68e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GKNPKEJL_01035	9.17e-59	-	-	-	-	-	-	-	-
GKNPKEJL_01037	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKNPKEJL_01038	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GKNPKEJL_01039	3.36e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
GKNPKEJL_01040	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GKNPKEJL_01041	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
GKNPKEJL_01042	9.39e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
GKNPKEJL_01043	9.3e-61	-	-	-	-	-	-	-	-
GKNPKEJL_01044	3e-54	-	-	-	-	-	-	-	-
GKNPKEJL_01046	1.35e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GKNPKEJL_01047	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GKNPKEJL_01048	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
GKNPKEJL_01049	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GKNPKEJL_01050	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
GKNPKEJL_01051	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
GKNPKEJL_01052	0.0	yhaN	-	-	L	-	-	-	AAA domain
GKNPKEJL_01053	9.31e-177	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKNPKEJL_01055	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
GKNPKEJL_01056	7.73e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01057	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GKNPKEJL_01058	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKNPKEJL_01059	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
GKNPKEJL_01060	3.53e-76	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
GKNPKEJL_01061	1.8e-308	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
GKNPKEJL_01062	6.79e-183	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GKNPKEJL_01063	7.52e-101	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GKNPKEJL_01064	2.32e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
GKNPKEJL_01065	1.21e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GKNPKEJL_01066	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
GKNPKEJL_01067	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
GKNPKEJL_01068	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKNPKEJL_01069	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
GKNPKEJL_01070	8.55e-46	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
GKNPKEJL_01071	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
GKNPKEJL_01072	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GKNPKEJL_01073	5.63e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
GKNPKEJL_01074	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKNPKEJL_01075	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKNPKEJL_01076	5.91e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKNPKEJL_01077	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKNPKEJL_01078	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
GKNPKEJL_01079	1.59e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
GKNPKEJL_01080	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKNPKEJL_01081	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
GKNPKEJL_01082	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKNPKEJL_01083	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
GKNPKEJL_01084	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
GKNPKEJL_01085	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
GKNPKEJL_01086	2.43e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKNPKEJL_01087	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
GKNPKEJL_01088	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKNPKEJL_01089	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
GKNPKEJL_01090	9.69e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
GKNPKEJL_01091	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
GKNPKEJL_01092	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
GKNPKEJL_01093	1.38e-155	csrR	-	-	K	-	-	-	response regulator
GKNPKEJL_01094	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GKNPKEJL_01095	2.48e-178	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01096	1.64e-135	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01097	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKNPKEJL_01098	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
GKNPKEJL_01099	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GKNPKEJL_01100	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
GKNPKEJL_01101	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
GKNPKEJL_01102	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKNPKEJL_01103	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKNPKEJL_01104	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKNPKEJL_01105	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
GKNPKEJL_01106	6.39e-261	-	-	-	-	-	-	-	-
GKNPKEJL_01107	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKNPKEJL_01108	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKNPKEJL_01109	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKNPKEJL_01110	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKNPKEJL_01111	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
GKNPKEJL_01112	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GKNPKEJL_01113	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
GKNPKEJL_01114	1.69e-166	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
GKNPKEJL_01115	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01116	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01117	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
GKNPKEJL_01118	4.95e-195	-	-	-	E	-	-	-	AzlC protein
GKNPKEJL_01119	9.06e-260	hpk31	-	-	T	-	-	-	Histidine kinase
GKNPKEJL_01120	3.27e-159	vanR	-	-	K	-	-	-	response regulator
GKNPKEJL_01121	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKNPKEJL_01122	5.36e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
GKNPKEJL_01123	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
GKNPKEJL_01124	1.58e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
GKNPKEJL_01125	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKNPKEJL_01126	3.97e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKNPKEJL_01127	1.73e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
GKNPKEJL_01128	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKNPKEJL_01129	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
GKNPKEJL_01130	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GKNPKEJL_01131	4.63e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
GKNPKEJL_01132	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GKNPKEJL_01133	6.29e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
GKNPKEJL_01134	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
GKNPKEJL_01135	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
GKNPKEJL_01136	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
GKNPKEJL_01137	1.77e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GKNPKEJL_01139	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01140	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKNPKEJL_01141	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKNPKEJL_01142	1.2e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01143	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01144	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01145	1.14e-231	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
GKNPKEJL_01146	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
GKNPKEJL_01147	7.72e-178	-	-	-	IQ	-	-	-	KR domain
GKNPKEJL_01148	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GKNPKEJL_01149	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
GKNPKEJL_01150	2.8e-315	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01151	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GKNPKEJL_01152	6.5e-71	-	-	-	-	-	-	-	-
GKNPKEJL_01153	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GKNPKEJL_01154	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
GKNPKEJL_01155	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GKNPKEJL_01156	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_01157	3.46e-207	-	-	-	-	-	-	-	-
GKNPKEJL_01158	9.77e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
GKNPKEJL_01159	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
GKNPKEJL_01160	6.79e-271	-	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_01161	3.18e-11	-	-	-	-	-	-	-	-
GKNPKEJL_01162	1.78e-83	-	-	-	-	-	-	-	-
GKNPKEJL_01163	1.37e-246	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
GKNPKEJL_01164	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
GKNPKEJL_01165	0.0	fusA1	-	-	J	-	-	-	elongation factor G
GKNPKEJL_01166	2.17e-213	-	-	-	GK	-	-	-	ROK family
GKNPKEJL_01167	9.75e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GKNPKEJL_01168	4.49e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
GKNPKEJL_01169	1.05e-310	-	-	-	E	-	-	-	amino acid
GKNPKEJL_01170	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
GKNPKEJL_01171	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
GKNPKEJL_01172	4.73e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKNPKEJL_01173	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKNPKEJL_01174	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GKNPKEJL_01175	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01176	5.75e-242	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKNPKEJL_01177	3.43e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GKNPKEJL_01178	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01179	1.08e-164	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01185	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
GKNPKEJL_01186	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
GKNPKEJL_01188	2.79e-153	-	-	-	I	-	-	-	phosphatase
GKNPKEJL_01189	5.02e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
GKNPKEJL_01190	2.09e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
GKNPKEJL_01191	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GKNPKEJL_01192	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
GKNPKEJL_01193	1.35e-210	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
GKNPKEJL_01194	7.03e-150	-	-	-	S	-	-	-	membrane
GKNPKEJL_01195	7.81e-141	-	-	-	S	-	-	-	VIT family
GKNPKEJL_01196	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GKNPKEJL_01197	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01198	4.49e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKNPKEJL_01199	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01200	2.46e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01201	7.14e-276	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GKNPKEJL_01202	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKNPKEJL_01203	8.46e-77	-	-	-	-	-	-	-	-
GKNPKEJL_01204	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
GKNPKEJL_01205	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GKNPKEJL_01206	1.91e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
GKNPKEJL_01207	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GKNPKEJL_01209	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKNPKEJL_01210	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
GKNPKEJL_01211	1.93e-241	-	-	-	I	-	-	-	Alpha beta
GKNPKEJL_01212	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_01213	5.69e-154	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
GKNPKEJL_01214	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
GKNPKEJL_01215	7.21e-205	-	-	-	K	-	-	-	LysR family
GKNPKEJL_01216	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GKNPKEJL_01217	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GKNPKEJL_01218	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKNPKEJL_01219	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
GKNPKEJL_01220	5.46e-207	mleR	-	-	K	-	-	-	LysR family
GKNPKEJL_01221	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKNPKEJL_01222	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
GKNPKEJL_01223	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
GKNPKEJL_01224	6.08e-213	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GKNPKEJL_01225	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
GKNPKEJL_01226	1.36e-35	-	-	-	-	-	-	-	-
GKNPKEJL_01227	3.67e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GKNPKEJL_01228	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKNPKEJL_01229	1.65e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01230	6.85e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01231	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKNPKEJL_01232	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
GKNPKEJL_01233	0.0	yagE	-	-	E	-	-	-	amino acid
GKNPKEJL_01234	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GKNPKEJL_01235	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GKNPKEJL_01236	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GKNPKEJL_01237	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKNPKEJL_01238	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKNPKEJL_01239	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01240	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01241	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKNPKEJL_01242	1.97e-293	-	-	-	-	-	-	-	-
GKNPKEJL_01243	1.77e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
GKNPKEJL_01244	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
GKNPKEJL_01245	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
GKNPKEJL_01246	1.12e-131	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
GKNPKEJL_01247	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
GKNPKEJL_01248	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
GKNPKEJL_01249	8.05e-194	-	-	-	-	-	-	-	-
GKNPKEJL_01250	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
GKNPKEJL_01251	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
GKNPKEJL_01252	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
GKNPKEJL_01253	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKNPKEJL_01254	6.08e-13	-	-	-	S	-	-	-	CsbD-like
GKNPKEJL_01255	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
GKNPKEJL_01256	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKNPKEJL_01257	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
GKNPKEJL_01258	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
GKNPKEJL_01259	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GKNPKEJL_01260	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
GKNPKEJL_01261	1.77e-202	-	-	-	EG	-	-	-	EamA-like transporter family
GKNPKEJL_01262	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKNPKEJL_01263	3.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
GKNPKEJL_01264	7.02e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
GKNPKEJL_01266	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
GKNPKEJL_01267	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKNPKEJL_01268	1.17e-78	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKNPKEJL_01269	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
GKNPKEJL_01270	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
GKNPKEJL_01271	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
GKNPKEJL_01272	1.82e-187	yidA	-	-	S	-	-	-	hydrolase
GKNPKEJL_01273	1.6e-100	-	-	-	-	-	-	-	-
GKNPKEJL_01274	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKNPKEJL_01275	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKNPKEJL_01276	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
GKNPKEJL_01277	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
GKNPKEJL_01278	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GKNPKEJL_01279	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GKNPKEJL_01280	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKNPKEJL_01281	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
GKNPKEJL_01282	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKNPKEJL_01283	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKNPKEJL_01284	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
GKNPKEJL_01285	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKNPKEJL_01286	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
GKNPKEJL_01288	1.02e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
GKNPKEJL_01289	1.09e-227	-	-	-	-	-	-	-	-
GKNPKEJL_01290	8.45e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
GKNPKEJL_01291	1.03e-213	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GKNPKEJL_01292	4.55e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GKNPKEJL_01293	3.71e-235	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
GKNPKEJL_01294	1.86e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
GKNPKEJL_01295	3.85e-72	-	-	-	-	-	-	-	-
GKNPKEJL_01296	1.08e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_01297	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
GKNPKEJL_01298	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GKNPKEJL_01299	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
GKNPKEJL_01300	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKNPKEJL_01301	5.93e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKNPKEJL_01302	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
GKNPKEJL_01303	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKNPKEJL_01304	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKNPKEJL_01305	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKNPKEJL_01306	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
GKNPKEJL_01307	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
GKNPKEJL_01308	1.13e-104	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
GKNPKEJL_01309	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKNPKEJL_01310	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKNPKEJL_01311	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
GKNPKEJL_01312	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKNPKEJL_01313	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKNPKEJL_01314	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
GKNPKEJL_01315	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKNPKEJL_01316	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKNPKEJL_01317	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GKNPKEJL_01318	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKNPKEJL_01319	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
GKNPKEJL_01320	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GKNPKEJL_01321	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
GKNPKEJL_01322	1.65e-206	-	-	-	S	-	-	-	reductase
GKNPKEJL_01324	0.0	-	-	-	S	-	-	-	amidohydrolase
GKNPKEJL_01325	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
GKNPKEJL_01326	1.36e-96	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
GKNPKEJL_01327	4.53e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
GKNPKEJL_01328	6.38e-151	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GKNPKEJL_01330	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
GKNPKEJL_01331	1.3e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
GKNPKEJL_01332	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
GKNPKEJL_01333	1.02e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GKNPKEJL_01334	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
GKNPKEJL_01335	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01336	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
GKNPKEJL_01337	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
GKNPKEJL_01338	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GKNPKEJL_01339	4.08e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
GKNPKEJL_01340	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
GKNPKEJL_01341	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
GKNPKEJL_01342	0.0	potE	-	-	E	-	-	-	Amino Acid
GKNPKEJL_01343	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
GKNPKEJL_01344	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
GKNPKEJL_01345	1.25e-42	-	-	-	-	-	-	-	-
GKNPKEJL_01346	2.86e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
GKNPKEJL_01347	3.17e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
GKNPKEJL_01348	8.95e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
GKNPKEJL_01349	8.1e-153	-	-	-	M	-	-	-	Bacterial sugar transferase
GKNPKEJL_01350	6.15e-83	-	-	-	-	-	-	-	-
GKNPKEJL_01351	1.69e-43	-	-	-	M	-	-	-	biosynthesis protein
GKNPKEJL_01352	2.42e-82	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
GKNPKEJL_01353	2.78e-96	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
GKNPKEJL_01354	9.41e-196	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
GKNPKEJL_01355	1.96e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
GKNPKEJL_01356	1.02e-289	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GKNPKEJL_01357	3.18e-89	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
GKNPKEJL_01358	2.16e-61	cps3I	-	-	G	-	-	-	Acyltransferase family
GKNPKEJL_01359	9.63e-105	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
GKNPKEJL_01360	5.82e-79	-	-	-	-	-	-	-	-
GKNPKEJL_01362	9.76e-93	-	-	-	O	-	-	-	Preprotein translocase subunit SecB
GKNPKEJL_01363	5.14e-217	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
GKNPKEJL_01364	8.9e-317	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GKNPKEJL_01366	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GKNPKEJL_01367	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
GKNPKEJL_01369	5.89e-82	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
GKNPKEJL_01370	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
GKNPKEJL_01372	0.0	snf	-	-	KL	-	-	-	domain protein
GKNPKEJL_01373	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
GKNPKEJL_01374	3.74e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GKNPKEJL_01375	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
GKNPKEJL_01376	1.08e-23	-	-	-	L	-	-	-	nuclease
GKNPKEJL_01377	3.78e-73	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GKNPKEJL_01378	6.12e-91	-	-	-	-	-	-	-	-
GKNPKEJL_01379	1.18e-134	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GKNPKEJL_01380	2.66e-156	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKNPKEJL_01381	6.38e-195	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
GKNPKEJL_01382	0.0	-	-	-	-	-	-	-	-
GKNPKEJL_01383	6.54e-108	-	-	-	-	-	-	-	-
GKNPKEJL_01384	0.0	-	-	-	-	-	-	-	-
GKNPKEJL_01386	5.59e-249	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKNPKEJL_01387	3.39e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
GKNPKEJL_01388	2.64e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GKNPKEJL_01389	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKNPKEJL_01390	4.08e-143	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
GKNPKEJL_01391	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
GKNPKEJL_01392	1.46e-263	-	-	-	G	-	-	-	Transporter, major facilitator family protein
GKNPKEJL_01393	3.37e-140	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
GKNPKEJL_01394	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
GKNPKEJL_01395	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKNPKEJL_01396	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GKNPKEJL_01397	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
GKNPKEJL_01398	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
GKNPKEJL_01399	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
GKNPKEJL_01400	3.21e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
GKNPKEJL_01401	9.08e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKNPKEJL_01402	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
GKNPKEJL_01403	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
GKNPKEJL_01404	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GKNPKEJL_01405	1.35e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
GKNPKEJL_01406	8e-145	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
GKNPKEJL_01407	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
GKNPKEJL_01408	3.19e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GKNPKEJL_01409	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
GKNPKEJL_01410	4.43e-191	-	-	-	O	-	-	-	Band 7 protein
GKNPKEJL_01411	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
GKNPKEJL_01412	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
GKNPKEJL_01413	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
GKNPKEJL_01414	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
GKNPKEJL_01415	3.4e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GKNPKEJL_01416	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GKNPKEJL_01417	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
GKNPKEJL_01418	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
GKNPKEJL_01419	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
GKNPKEJL_01420	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKNPKEJL_01421	4.79e-273	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
GKNPKEJL_01422	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
GKNPKEJL_01423	2.1e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
GKNPKEJL_01424	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
GKNPKEJL_01425	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
GKNPKEJL_01426	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
GKNPKEJL_01427	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
GKNPKEJL_01428	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
GKNPKEJL_01429	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKNPKEJL_01430	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
GKNPKEJL_01431	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKNPKEJL_01432	3.18e-107	-	-	-	-	-	-	-	-
GKNPKEJL_01433	2.36e-185	-	-	-	-	-	-	-	-
GKNPKEJL_01435	1.42e-35	-	-	-	-	-	-	-	-
GKNPKEJL_01436	3.34e-60	-	-	-	-	-	-	-	-
GKNPKEJL_01437	2.74e-265	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
GKNPKEJL_01438	1.02e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
GKNPKEJL_01439	6.65e-187	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
GKNPKEJL_01443	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKNPKEJL_01444	5.06e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
GKNPKEJL_01445	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKNPKEJL_01446	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKNPKEJL_01447	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKNPKEJL_01448	1.91e-261	camS	-	-	S	-	-	-	sex pheromone
GKNPKEJL_01449	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKNPKEJL_01450	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
GKNPKEJL_01451	2.28e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKNPKEJL_01452	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKNPKEJL_01453	8.45e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
GKNPKEJL_01454	5.41e-25	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
GKNPKEJL_01455	6.59e-144	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
GKNPKEJL_01456	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
GKNPKEJL_01457	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKNPKEJL_01458	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKNPKEJL_01459	1.43e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKNPKEJL_01460	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKNPKEJL_01461	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKNPKEJL_01462	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
GKNPKEJL_01463	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKNPKEJL_01464	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKNPKEJL_01465	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKNPKEJL_01466	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
GKNPKEJL_01467	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKNPKEJL_01468	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKNPKEJL_01469	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKNPKEJL_01470	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GKNPKEJL_01471	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
GKNPKEJL_01472	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKNPKEJL_01473	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKNPKEJL_01474	1.06e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKNPKEJL_01475	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKNPKEJL_01476	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKNPKEJL_01477	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKNPKEJL_01478	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKNPKEJL_01479	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKNPKEJL_01480	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKNPKEJL_01481	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
GKNPKEJL_01482	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKNPKEJL_01483	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKNPKEJL_01484	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKNPKEJL_01485	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKNPKEJL_01486	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKNPKEJL_01487	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKNPKEJL_01488	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
GKNPKEJL_01489	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKNPKEJL_01490	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
GKNPKEJL_01491	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
GKNPKEJL_01492	1.74e-307	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
GKNPKEJL_01493	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKNPKEJL_01494	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
GKNPKEJL_01495	2.07e-202	gspA	-	-	M	-	-	-	family 8
GKNPKEJL_01496	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GKNPKEJL_01497	7.49e-124	-	-	-	-	-	-	-	-
GKNPKEJL_01498	5.11e-208	-	-	-	S	-	-	-	EDD domain protein, DegV family
GKNPKEJL_01499	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
GKNPKEJL_01500	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GKNPKEJL_01501	9.15e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
GKNPKEJL_01502	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GKNPKEJL_01503	6.71e-92	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKNPKEJL_01504	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
GKNPKEJL_01505	2.57e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
GKNPKEJL_01506	9.83e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
GKNPKEJL_01507	4.13e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
GKNPKEJL_01508	2.02e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
GKNPKEJL_01509	0.0	-	-	-	L	-	-	-	DNA helicase
GKNPKEJL_01510	1.1e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GKNPKEJL_01512	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKNPKEJL_01513	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
GKNPKEJL_01514	4.89e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKNPKEJL_01515	3.74e-58	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
GKNPKEJL_01516	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
GKNPKEJL_01517	1.47e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GKNPKEJL_01518	3.24e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GKNPKEJL_01519	1.97e-198	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GKNPKEJL_01520	2.11e-151	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
GKNPKEJL_01521	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GKNPKEJL_01522	1.47e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKNPKEJL_01523	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01524	8.7e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
GKNPKEJL_01525	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GKNPKEJL_01526	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
GKNPKEJL_01527	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
GKNPKEJL_01528	8.34e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01529	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01530	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
GKNPKEJL_01531	3.87e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_01532	1.83e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
GKNPKEJL_01533	4.44e-11	-	-	-	-	-	-	-	-
GKNPKEJL_01534	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
GKNPKEJL_01535	0.0	cadA	-	-	P	-	-	-	P-type ATPase
GKNPKEJL_01536	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
GKNPKEJL_01537	7.41e-163	-	-	-	-	-	-	-	-
GKNPKEJL_01538	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GKNPKEJL_01539	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
GKNPKEJL_01541	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
GKNPKEJL_01542	4.51e-101	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
GKNPKEJL_01543	1.09e-226	ydhF	-	-	S	-	-	-	Aldo keto reductase
GKNPKEJL_01545	8.69e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKNPKEJL_01546	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
GKNPKEJL_01547	6.13e-133	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
GKNPKEJL_01549	3.97e-232	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKNPKEJL_01550	9.5e-190	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GKNPKEJL_01551	4.52e-93	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GKNPKEJL_01552	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
GKNPKEJL_01553	1.14e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
GKNPKEJL_01554	2.73e-50	-	-	-	-	-	-	-	-
GKNPKEJL_01555	8.61e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
GKNPKEJL_01556	2.03e-307	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
GKNPKEJL_01558	5.31e-169	-	-	-	-	-	-	-	-
GKNPKEJL_01559	9.9e-49	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
GKNPKEJL_01560	6.08e-249	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
GKNPKEJL_01561	3.04e-29	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
GKNPKEJL_01562	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
GKNPKEJL_01563	2.66e-275	-	-	-	K	-	-	-	DNA binding
GKNPKEJL_01564	0.0	-	-	-	L	-	-	-	helicase activity
GKNPKEJL_01568	8.74e-300	-	-	-	L	-	-	-	Integrase core domain
GKNPKEJL_01569	9.96e-31	-	-	-	L	-	-	-	helicase activity
GKNPKEJL_01570	1.69e-46	-	-	-	L	-	-	-	helicase activity
GKNPKEJL_01572	1.03e-72	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKNPKEJL_01575	3.13e-164	-	-	-	M	-	-	-	PFAM NLP P60 protein
GKNPKEJL_01576	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GKNPKEJL_01577	5.58e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GKNPKEJL_01578	1.61e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01579	1.93e-119	-	-	-	P	-	-	-	Cadmium resistance transporter
GKNPKEJL_01580	2.29e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
GKNPKEJL_01581	2.82e-94	-	-	-	M	-	-	-	domain protein
GKNPKEJL_01582	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
GKNPKEJL_01583	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GKNPKEJL_01584	2.19e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
GKNPKEJL_01585	1.21e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GKNPKEJL_01586	6.47e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GKNPKEJL_01587	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
GKNPKEJL_01588	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
GKNPKEJL_01589	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
GKNPKEJL_01590	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
GKNPKEJL_01591	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
GKNPKEJL_01592	1.05e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKNPKEJL_01593	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
GKNPKEJL_01594	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
GKNPKEJL_01595	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKNPKEJL_01596	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKNPKEJL_01597	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKNPKEJL_01598	9.72e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKNPKEJL_01599	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKNPKEJL_01600	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKNPKEJL_01601	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
GKNPKEJL_01602	3.81e-292	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
GKNPKEJL_01603	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
GKNPKEJL_01604	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
GKNPKEJL_01605	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKNPKEJL_01606	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKNPKEJL_01607	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKNPKEJL_01608	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKNPKEJL_01609	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKNPKEJL_01610	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKNPKEJL_01611	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
GKNPKEJL_01612	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
GKNPKEJL_01613	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
GKNPKEJL_01614	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
GKNPKEJL_01615	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
GKNPKEJL_01616	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GKNPKEJL_01617	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
GKNPKEJL_01618	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
GKNPKEJL_01619	2.01e-76	-	-	-	-	-	-	-	-
GKNPKEJL_01620	0.0	-	-	-	M	-	-	-	domain protein
GKNPKEJL_01621	9.23e-138	-	-	-	-	-	-	-	-
GKNPKEJL_01623	2.54e-199	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GKNPKEJL_01624	4.95e-92	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GKNPKEJL_01626	2.13e-74	-	-	-	-	-	-	-	-
GKNPKEJL_01628	1.23e-110	-	-	-	-	-	-	-	-
GKNPKEJL_01629	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GKNPKEJL_01630	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
GKNPKEJL_01631	1.31e-81	-	-	-	S	-	-	-	Cupredoxin-like domain
GKNPKEJL_01632	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
GKNPKEJL_01633	3.18e-206	-	-	-	EG	-	-	-	EamA-like transporter family
GKNPKEJL_01634	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
GKNPKEJL_01635	1.31e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKNPKEJL_01636	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
GKNPKEJL_01637	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
GKNPKEJL_01638	2.08e-208	xylR	-	-	GK	-	-	-	ROK family
GKNPKEJL_01639	2.49e-39	-	-	-	-	-	-	-	-
GKNPKEJL_01640	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
GKNPKEJL_01641	6.42e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GKNPKEJL_01642	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GKNPKEJL_01643	0.0	yclK	-	-	T	-	-	-	Histidine kinase
GKNPKEJL_01644	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
GKNPKEJL_01646	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
GKNPKEJL_01647	9.84e-194	-	-	-	S	-	-	-	Cof-like hydrolase
GKNPKEJL_01648	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_01649	0.0	oatA	-	-	I	-	-	-	Acyltransferase
GKNPKEJL_01650	5.17e-70	-	-	-	-	-	-	-	-
GKNPKEJL_01651	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKNPKEJL_01652	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKNPKEJL_01653	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
GKNPKEJL_01654	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKNPKEJL_01655	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
GKNPKEJL_01656	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GKNPKEJL_01657	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKNPKEJL_01658	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
GKNPKEJL_01659	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GKNPKEJL_01660	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GKNPKEJL_01661	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKNPKEJL_01662	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
GKNPKEJL_01663	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
GKNPKEJL_01664	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKNPKEJL_01665	9.61e-137	-	-	-	-	-	-	-	-
GKNPKEJL_01666	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKNPKEJL_01667	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKNPKEJL_01668	3.43e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
GKNPKEJL_01669	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GKNPKEJL_01670	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GKNPKEJL_01671	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GKNPKEJL_01672	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKNPKEJL_01673	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKNPKEJL_01674	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
GKNPKEJL_01675	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKNPKEJL_01677	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKNPKEJL_01678	1.83e-21	-	-	-	-	-	-	-	-
GKNPKEJL_01680	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
GKNPKEJL_01681	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
GKNPKEJL_01682	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
GKNPKEJL_01683	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
GKNPKEJL_01684	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKNPKEJL_01685	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKNPKEJL_01686	2.12e-19	-	-	-	-	-	-	-	-
GKNPKEJL_01687	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
GKNPKEJL_01688	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GKNPKEJL_01689	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
GKNPKEJL_01690	5.89e-201	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
GKNPKEJL_01691	4.47e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
GKNPKEJL_01692	2.38e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKNPKEJL_01693	8.82e-203	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
GKNPKEJL_01694	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
GKNPKEJL_01695	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
GKNPKEJL_01696	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GKNPKEJL_01697	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
GKNPKEJL_01698	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKNPKEJL_01699	7.99e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKNPKEJL_01700	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
GKNPKEJL_01701	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
GKNPKEJL_01702	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKNPKEJL_01703	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKNPKEJL_01704	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKNPKEJL_01705	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
GKNPKEJL_01706	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
GKNPKEJL_01707	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
GKNPKEJL_01708	2.24e-301	-	-	-	EGP	-	-	-	Major Facilitator
GKNPKEJL_01715	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GKNPKEJL_01716	1.53e-61	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
GKNPKEJL_01717	1.93e-66	-	-	-	L	-	-	-	four-way junction helicase activity
GKNPKEJL_01721	2.21e-23	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
GKNPKEJL_01722	1.7e-20	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
GKNPKEJL_01723	5.13e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKNPKEJL_01724	5.9e-14	-	-	-	T	-	-	-	SpoVT / AbrB like domain
GKNPKEJL_01727	8.79e-81	-	-	-	-	-	-	-	-
GKNPKEJL_01730	5.99e-13	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GKNPKEJL_01733	5.49e-183	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
GKNPKEJL_01734	4.59e-40	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
GKNPKEJL_01735	1.53e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GKNPKEJL_01736	4.46e-199	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
GKNPKEJL_01737	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKNPKEJL_01739	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKNPKEJL_01740	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKNPKEJL_01741	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
GKNPKEJL_01742	0.0	-	-	-	E	-	-	-	amino acid
GKNPKEJL_01743	0.0	ydaO	-	-	E	-	-	-	amino acid
GKNPKEJL_01744	3.74e-53	-	-	-	-	-	-	-	-
GKNPKEJL_01745	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
GKNPKEJL_01746	6.08e-102	-	-	-	-	-	-	-	-
GKNPKEJL_01747	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
GKNPKEJL_01748	4.84e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
GKNPKEJL_01749	4.37e-39	-	-	-	-	-	-	-	-
GKNPKEJL_01750	3.3e-265	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
GKNPKEJL_01752	5.28e-76	-	-	-	-	-	-	-	-
GKNPKEJL_01753	7.55e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GKNPKEJL_01754	6.63e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
GKNPKEJL_01755	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
GKNPKEJL_01756	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKNPKEJL_01757	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GKNPKEJL_01758	1.18e-176	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKNPKEJL_01759	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKNPKEJL_01760	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKNPKEJL_01761	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKNPKEJL_01762	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKNPKEJL_01763	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GKNPKEJL_01764	1.11e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKNPKEJL_01765	3.66e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKNPKEJL_01766	1.2e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GKNPKEJL_01767	3.95e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKNPKEJL_01768	8.89e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
GKNPKEJL_01769	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKNPKEJL_01770	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
GKNPKEJL_01771	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
GKNPKEJL_01772	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKNPKEJL_01773	8.53e-120	-	-	-	-	-	-	-	-
GKNPKEJL_01776	1.27e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GKNPKEJL_01777	2.98e-163	-	-	-	O	-	-	-	Bacterial dnaA protein
GKNPKEJL_01778	6.97e-244	-	-	-	L	-	-	-	Integrase core domain
GKNPKEJL_01779	2.77e-19	-	-	-	L	-	-	-	Integrase core domain
GKNPKEJL_01780	2.31e-159	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GKNPKEJL_01781	3.58e-253	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GKNPKEJL_01782	9.09e-142	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
GKNPKEJL_01783	3.7e-297	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKNPKEJL_01784	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
GKNPKEJL_01785	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
GKNPKEJL_01786	2.65e-13	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GKNPKEJL_01787	1.61e-50	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GKNPKEJL_01788	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GKNPKEJL_01789	7.92e-76	-	-	-	-	-	-	-	-
GKNPKEJL_01790	1.28e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
GKNPKEJL_01791	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GKNPKEJL_01792	2.36e-69	-	-	-	-	-	-	-	-
GKNPKEJL_01793	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKNPKEJL_01794	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKNPKEJL_01795	1.26e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
GKNPKEJL_01796	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKNPKEJL_01797	1.54e-96	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01798	3.67e-46	-	-	-	-	-	-	-	-
GKNPKEJL_01799	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
GKNPKEJL_01800	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GKNPKEJL_01801	1.55e-109	-	-	-	-	-	-	-	-
GKNPKEJL_01802	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKNPKEJL_01803	3.99e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKNPKEJL_01804	1.06e-50	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKNPKEJL_01805	9.85e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
GKNPKEJL_01806	2.61e-236	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GKNPKEJL_01807	2.82e-133	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GKNPKEJL_01808	1.35e-276	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GKNPKEJL_01809	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
GKNPKEJL_01810	3e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GKNPKEJL_01811	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
GKNPKEJL_01812	1.5e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKNPKEJL_01813	2.57e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
GKNPKEJL_01814	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
GKNPKEJL_01815	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKNPKEJL_01818	2.06e-247	-	-	-	L	-	-	-	Integrase core domain
GKNPKEJL_01819	6.66e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
GKNPKEJL_01820	8.66e-89	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GKNPKEJL_01821	1.5e-241	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GKNPKEJL_01822	0.0	arcT	-	-	E	-	-	-	Dipeptidase
GKNPKEJL_01823	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
GKNPKEJL_01824	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
GKNPKEJL_01825	3.66e-183	-	-	-	V	-	-	-	Beta-lactamase enzyme family
GKNPKEJL_01826	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
GKNPKEJL_01827	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKNPKEJL_01828	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GKNPKEJL_01829	2.99e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GKNPKEJL_01830	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKNPKEJL_01831	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
GKNPKEJL_01832	1.38e-37	-	-	-	-	-	-	-	-
GKNPKEJL_01833	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
GKNPKEJL_01834	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
GKNPKEJL_01835	1.35e-182	-	-	-	G	-	-	-	MucBP domain
GKNPKEJL_01836	2.26e-145	-	-	-	-	-	-	-	-
GKNPKEJL_01837	9.75e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01838	2.41e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
GKNPKEJL_01839	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
GKNPKEJL_01840	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
GKNPKEJL_01841	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKNPKEJL_01842	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKNPKEJL_01843	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKNPKEJL_01844	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GKNPKEJL_01845	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKNPKEJL_01846	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
GKNPKEJL_01847	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
GKNPKEJL_01848	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
GKNPKEJL_01849	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKNPKEJL_01850	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKNPKEJL_01851	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
GKNPKEJL_01852	1.19e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
GKNPKEJL_01853	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
GKNPKEJL_01854	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
GKNPKEJL_01855	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
GKNPKEJL_01856	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKNPKEJL_01857	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKNPKEJL_01858	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
GKNPKEJL_01859	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKNPKEJL_01860	1.1e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
GKNPKEJL_01861	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKNPKEJL_01862	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKNPKEJL_01863	3.55e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GKNPKEJL_01864	1.29e-239	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
GKNPKEJL_01865	2.29e-158	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
GKNPKEJL_01866	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKNPKEJL_01867	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKNPKEJL_01868	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
GKNPKEJL_01869	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
GKNPKEJL_01870	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKNPKEJL_01871	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
GKNPKEJL_01872	6.21e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
GKNPKEJL_01873	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKNPKEJL_01874	1.51e-289	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GKNPKEJL_01875	1.75e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
GKNPKEJL_01876	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GKNPKEJL_01877	3.07e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNPKEJL_01878	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
GKNPKEJL_01879	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKNPKEJL_01880	1.96e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
GKNPKEJL_01881	2.9e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
GKNPKEJL_01882	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKNPKEJL_01883	2.55e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKNPKEJL_01884	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKNPKEJL_01885	4.25e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKNPKEJL_01886	6.34e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
GKNPKEJL_01887	6.98e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GKNPKEJL_01888	4.85e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKNPKEJL_01889	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
GKNPKEJL_01890	1.51e-112	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
GKNPKEJL_01891	1.1e-63	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKNPKEJL_01892	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GKNPKEJL_01893	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
GKNPKEJL_01894	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
GKNPKEJL_01895	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
GKNPKEJL_01896	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
GKNPKEJL_01897	1.01e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
GKNPKEJL_01898	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
GKNPKEJL_01899	5.8e-149	-	-	-	I	-	-	-	Acid phosphatase homologues
GKNPKEJL_01900	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
GKNPKEJL_01901	6.12e-296	-	-	-	P	-	-	-	Chloride transporter, ClC family
GKNPKEJL_01902	2.71e-151	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GKNPKEJL_01903	3e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GKNPKEJL_01904	2.03e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GKNPKEJL_01905	6.11e-68	-	-	-	-	-	-	-	-
GKNPKEJL_01906	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
GKNPKEJL_01907	4.93e-35	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKNPKEJL_01908	1.2e-238	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKNPKEJL_01909	3.05e-69	-	-	-	-	-	-	-	-
GKNPKEJL_01910	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
GKNPKEJL_01911	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GKNPKEJL_01912	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GKNPKEJL_01913	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
GKNPKEJL_01915	2.54e-60	yrvD	-	-	S	-	-	-	Pfam:DUF1049
GKNPKEJL_01916	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GKNPKEJL_01917	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
GKNPKEJL_01918	1.01e-28	-	-	-	-	-	-	-	-
GKNPKEJL_01919	4.22e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GKNPKEJL_01920	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
GKNPKEJL_01921	9.59e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
GKNPKEJL_01922	6.61e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
GKNPKEJL_01923	4.86e-258	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GKNPKEJL_01925	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKNPKEJL_01926	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
GKNPKEJL_01927	5.64e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKNPKEJL_01928	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKNPKEJL_01929	2.23e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
GKNPKEJL_01930	7.69e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
GKNPKEJL_01931	1.21e-286	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKNPKEJL_01932	6.2e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GKNPKEJL_01933	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKNPKEJL_01934	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
GKNPKEJL_01935	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKNPKEJL_01936	1.55e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
GKNPKEJL_01937	7.89e-168	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
GKNPKEJL_01943	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
GKNPKEJL_01944	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
GKNPKEJL_01946	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GKNPKEJL_01947	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GKNPKEJL_01948	2.41e-315	yycH	-	-	S	-	-	-	YycH protein
GKNPKEJL_01949	4.13e-192	yycI	-	-	S	-	-	-	YycH protein
GKNPKEJL_01950	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
GKNPKEJL_01951	2.25e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
GKNPKEJL_01952	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
GKNPKEJL_01953	1.14e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GKNPKEJL_01954	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKNPKEJL_01956	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
GKNPKEJL_01957	4.85e-245	isp	-	-	L	-	-	-	Transposase
GKNPKEJL_01959	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
GKNPKEJL_01960	2.84e-73	-	-	-	-	-	-	-	-
GKNPKEJL_01962	1.13e-130	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKNPKEJL_01963	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKNPKEJL_01964	5.87e-65	-	-	-	-	-	-	-	-
GKNPKEJL_01965	5.28e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
GKNPKEJL_01966	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
GKNPKEJL_01967	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GKNPKEJL_01968	7.28e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
GKNPKEJL_01969	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
GKNPKEJL_01970	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GKNPKEJL_01971	5.27e-64	-	-	-	-	-	-	-	-
GKNPKEJL_01972	2.21e-11	isp	-	-	L	-	-	-	Transposase