ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KAKDNLLK_00003 1.85e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KAKDNLLK_00004 4.09e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KAKDNLLK_00005 6.79e-181 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KAKDNLLK_00006 4.3e-68 - - - - - - - -
KAKDNLLK_00007 0.0 - - - S - - - SEC-C Motif Domain Protein
KAKDNLLK_00008 7.67e-149 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
KAKDNLLK_00009 2.12e-97 - - - - - - - -
KAKDNLLK_00010 3.37e-222 - - - - - - - -
KAKDNLLK_00011 1.48e-226 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
KAKDNLLK_00012 6.75e-171 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KAKDNLLK_00013 4.36e-166 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAKDNLLK_00014 9.93e-99 - - - S - - - Flavodoxin
KAKDNLLK_00015 3.65e-81 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
KAKDNLLK_00016 5.33e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
KAKDNLLK_00017 2.14e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
KAKDNLLK_00018 7.71e-185 - - - H - - - geranyltranstransferase activity
KAKDNLLK_00019 6.03e-222 - - - - - - - -
KAKDNLLK_00021 4.31e-149 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
KAKDNLLK_00022 6.89e-236 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
KAKDNLLK_00023 7.46e-59 - - - - - - - -
KAKDNLLK_00024 3.21e-124 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KAKDNLLK_00025 2.74e-98 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
KAKDNLLK_00026 1.93e-285 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
KAKDNLLK_00027 1.42e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
KAKDNLLK_00028 9.1e-237 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
KAKDNLLK_00029 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KAKDNLLK_00030 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KAKDNLLK_00031 7.01e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
KAKDNLLK_00032 1.29e-165 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
KAKDNLLK_00033 1.09e-195 - - - EG - - - EamA-like transporter family
KAKDNLLK_00034 9.45e-152 - - - L - - - Integrase
KAKDNLLK_00035 1.2e-202 rssA - - S - - - Phospholipase, patatin family
KAKDNLLK_00036 1.79e-312 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
KAKDNLLK_00037 1.19e-258 xerS - - L - - - Belongs to the 'phage' integrase family
KAKDNLLK_00039 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KAKDNLLK_00040 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
KAKDNLLK_00041 5.4e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAKDNLLK_00042 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAKDNLLK_00043 5.15e-199 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
KAKDNLLK_00044 8.61e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KAKDNLLK_00045 6.01e-287 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KAKDNLLK_00046 5.1e-97 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KAKDNLLK_00047 7.97e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KAKDNLLK_00048 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
KAKDNLLK_00049 5.91e-184 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAKDNLLK_00050 4.82e-180 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
KAKDNLLK_00051 2.46e-171 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KAKDNLLK_00059 2.65e-247 - - - M - - - transferase activity, transferring glycosyl groups
KAKDNLLK_00060 4.37e-266 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
KAKDNLLK_00061 0.0 - - - M - - - transferase activity, transferring glycosyl groups
KAKDNLLK_00062 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
KAKDNLLK_00063 8.53e-213 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
KAKDNLLK_00064 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KAKDNLLK_00065 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KAKDNLLK_00066 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KAKDNLLK_00068 0.0 - - - M - - - Pfam:DUF1792
KAKDNLLK_00069 0.0 - - - M - - - family 8
KAKDNLLK_00071 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
KAKDNLLK_00079 5.93e-155 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KAKDNLLK_00080 7.45e-268 - - - L - - - transposase IS116 IS110 IS902 family protein
KAKDNLLK_00081 1.08e-70 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KAKDNLLK_00082 2.18e-152 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KAKDNLLK_00087 7.36e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAKDNLLK_00088 5.23e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAKDNLLK_00089 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAKDNLLK_00090 2.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KAKDNLLK_00091 7.76e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAKDNLLK_00092 1.98e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAKDNLLK_00093 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAKDNLLK_00094 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAKDNLLK_00095 3.11e-247 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KAKDNLLK_00096 8.26e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAKDNLLK_00097 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KAKDNLLK_00098 4.09e-310 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KAKDNLLK_00099 3.05e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAKDNLLK_00100 1.59e-226 - - - - - - - -
KAKDNLLK_00101 5.74e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAKDNLLK_00102 8.03e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
KAKDNLLK_00112 8.94e-232 - - - - - - - -
KAKDNLLK_00113 3.16e-195 - - - G - - - Belongs to the phosphoglycerate mutase family
KAKDNLLK_00114 2.78e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KAKDNLLK_00115 1.43e-133 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KAKDNLLK_00116 3.69e-92 - - - - - - - -
KAKDNLLK_00117 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KAKDNLLK_00118 3.55e-136 - - - L - - - nuclease
KAKDNLLK_00119 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
KAKDNLLK_00120 6.46e-265 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KAKDNLLK_00121 4.3e-229 - - - M - - - Glycosyl hydrolases family 25
KAKDNLLK_00122 1.44e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
KAKDNLLK_00124 4.74e-51 - - - - ko:K18829 - ko00000,ko02048 -
KAKDNLLK_00125 1.25e-89 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
KAKDNLLK_00127 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KAKDNLLK_00128 5.36e-219 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KAKDNLLK_00129 9.76e-93 - - - O - - - Preprotein translocase subunit SecB
KAKDNLLK_00131 8.27e-79 - - - - - - - -
KAKDNLLK_00132 4.95e-38 - - - S - - - Protein of unknown function (DUF4065)
KAKDNLLK_00134 9.94e-30 - - - S - - - Bacteriophage abortive infection AbiH
KAKDNLLK_00135 2.12e-140 - - - L - - - transposase IS116 IS110 IS902 family protein
KAKDNLLK_00136 4.78e-60 - - - L - - - transposase IS116 IS110 IS902 family protein
KAKDNLLK_00137 7.94e-55 - - - L ko:K07484 - ko00000 Transposase IS66 family
KAKDNLLK_00138 6.42e-155 - - - K - - - AAA domain
KAKDNLLK_00140 5.68e-37 - - - L - - - AAA ATPase domain
KAKDNLLK_00141 5.62e-169 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KAKDNLLK_00142 1.57e-261 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KAKDNLLK_00143 2.99e-234 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KAKDNLLK_00144 2.56e-271 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KAKDNLLK_00145 8.37e-39 - - - - - - - -
KAKDNLLK_00146 4.73e-76 wbbI - - M - - - Involved in the transfer of galactofuranose (Galf) onto an alpha-D-gluco-configured acceptor substrate to form a beta-1,6- linkage. It uses n-octyl alpha-D-glucopyranoside as an acceptor substrate for the addition of galactofuranose from the donor substrate UDP-galactofuranose. It is not able to use beta-D- glucopyranoside isomers
KAKDNLLK_00147 1.57e-98 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KAKDNLLK_00148 4.91e-143 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KAKDNLLK_00149 2.05e-61 - - - S - - - Glycosyltransferase family 28 C-terminal domain
KAKDNLLK_00150 6.72e-97 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
KAKDNLLK_00151 5.79e-138 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
KAKDNLLK_00152 1.84e-159 ywqD - - D - - - Capsular exopolysaccharide family
KAKDNLLK_00153 2.27e-190 epsB - - M - - - biosynthesis protein
KAKDNLLK_00154 3.45e-220 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KAKDNLLK_00155 4.6e-89 - - - K - - - Transcriptional regulator, HxlR family
KAKDNLLK_00156 1.01e-163 - - - - - - - -
KAKDNLLK_00157 2.87e-132 - - - K - - - DNA-templated transcription, initiation
KAKDNLLK_00158 1.89e-47 - - - - - - - -
KAKDNLLK_00159 1.16e-108 - - - - - - - -
KAKDNLLK_00160 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KAKDNLLK_00161 1.1e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KAKDNLLK_00162 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
KAKDNLLK_00163 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KAKDNLLK_00165 4.05e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KAKDNLLK_00166 1.16e-133 - - - V - - - VanZ like family
KAKDNLLK_00167 7.03e-33 - - - - - - - -
KAKDNLLK_00168 5.03e-111 - - - S - - - Short repeat of unknown function (DUF308)
KAKDNLLK_00169 2.65e-102 - - - S - - - Psort location Cytoplasmic, score
KAKDNLLK_00170 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
KAKDNLLK_00171 4.45e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KAKDNLLK_00172 3.16e-197 yeaE - - S - - - Aldo keto
KAKDNLLK_00173 3.25e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KAKDNLLK_00174 1.98e-298 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KAKDNLLK_00175 8.45e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KAKDNLLK_00176 2.76e-138 - - - M - - - LysM domain protein
KAKDNLLK_00177 0.0 - - - EP - - - Psort location Cytoplasmic, score
KAKDNLLK_00178 2.02e-92 - - - M - - - LysM domain protein
KAKDNLLK_00179 9.49e-206 - - - O - - - Uncharacterized protein family (UPF0051)
KAKDNLLK_00180 1.37e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAKDNLLK_00181 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KAKDNLLK_00182 5.68e-313 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
KAKDNLLK_00183 1.05e-126 - - - K - - - Acetyltransferase (GNAT) domain
KAKDNLLK_00184 3.44e-194 - - - L ko:K07484 - ko00000 Transposase IS66 family
KAKDNLLK_00185 2.02e-37 - - - L ko:K07484 - ko00000 Transposase IS66 family
KAKDNLLK_00186 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
KAKDNLLK_00187 1.81e-37 - - - - - - - -
KAKDNLLK_00188 0.0 - - - G - - - Peptidase_C39 like family
KAKDNLLK_00189 1.83e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
KAKDNLLK_00190 7.88e-136 - - - S - - - Protein of unknown function (DUF1461)
KAKDNLLK_00191 2.87e-171 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KAKDNLLK_00192 2.28e-121 yutD - - S - - - Protein of unknown function (DUF1027)
KAKDNLLK_00193 9.2e-148 - - - S - - - Calcineurin-like phosphoesterase
KAKDNLLK_00194 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAKDNLLK_00195 5.09e-186 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
KAKDNLLK_00197 1.88e-91 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
KAKDNLLK_00198 2.38e-56 - - - - - - - -
KAKDNLLK_00199 1.43e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
KAKDNLLK_00200 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
KAKDNLLK_00201 3.85e-236 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KAKDNLLK_00202 1.2e-234 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
KAKDNLLK_00203 1.43e-167 yebC - - K - - - Transcriptional regulatory protein
KAKDNLLK_00204 1.34e-177 - - - - - - - -
KAKDNLLK_00205 1.56e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KAKDNLLK_00206 8.87e-269 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KAKDNLLK_00207 1.84e-75 - - - - - - - -
KAKDNLLK_00208 1.54e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KAKDNLLK_00209 6.5e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KAKDNLLK_00210 1.1e-195 - - - S - - - haloacid dehalogenase-like hydrolase
KAKDNLLK_00211 1.48e-99 ykuL - - S - - - (CBS) domain
KAKDNLLK_00212 2.34e-120 - - - S ko:K07095 - ko00000 Phosphoesterase
KAKDNLLK_00213 6.73e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAKDNLLK_00214 1.67e-180 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KAKDNLLK_00215 3.51e-125 yslB - - S - - - Protein of unknown function (DUF2507)
KAKDNLLK_00216 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KAKDNLLK_00217 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KAKDNLLK_00218 7.7e-117 cvpA - - S - - - Colicin V production protein
KAKDNLLK_00219 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
KAKDNLLK_00220 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAKDNLLK_00221 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
KAKDNLLK_00222 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAKDNLLK_00223 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KAKDNLLK_00224 2.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
KAKDNLLK_00225 7.54e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KAKDNLLK_00226 2.99e-249 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KAKDNLLK_00227 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KAKDNLLK_00228 5.28e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KAKDNLLK_00229 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAKDNLLK_00230 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAKDNLLK_00231 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KAKDNLLK_00232 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAKDNLLK_00233 2.04e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KAKDNLLK_00234 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAKDNLLK_00235 4.84e-196 - - - S - - - Helix-turn-helix domain
KAKDNLLK_00236 1.92e-316 ymfH - - S - - - Peptidase M16
KAKDNLLK_00237 2.38e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
KAKDNLLK_00238 4.04e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KAKDNLLK_00239 2.06e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00240 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KAKDNLLK_00241 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
KAKDNLLK_00242 7.72e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KAKDNLLK_00243 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
KAKDNLLK_00244 6.98e-156 radC - - L ko:K03630 - ko00000 DNA repair protein
KAKDNLLK_00245 5.01e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KAKDNLLK_00246 8.62e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KAKDNLLK_00247 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KAKDNLLK_00248 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KAKDNLLK_00249 1.63e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
KAKDNLLK_00250 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
KAKDNLLK_00251 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KAKDNLLK_00252 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAKDNLLK_00253 8.29e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KAKDNLLK_00254 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KAKDNLLK_00255 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAKDNLLK_00256 9.2e-303 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KAKDNLLK_00257 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
KAKDNLLK_00258 3e-229 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
KAKDNLLK_00259 2.97e-124 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KAKDNLLK_00260 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KAKDNLLK_00261 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KAKDNLLK_00262 2.4e-180 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KAKDNLLK_00263 4.16e-180 - - - S - - - Membrane
KAKDNLLK_00264 2e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
KAKDNLLK_00265 9.79e-29 - - - - - - - -
KAKDNLLK_00266 4.1e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KAKDNLLK_00267 3.96e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KAKDNLLK_00268 3.61e-61 - - - - - - - -
KAKDNLLK_00269 1.95e-109 uspA - - T - - - universal stress protein
KAKDNLLK_00270 1.85e-265 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
KAKDNLLK_00271 1.46e-201 yvgN - - S - - - Aldo keto reductase
KAKDNLLK_00272 1.32e-136 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
KAKDNLLK_00273 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
KAKDNLLK_00274 2.32e-179 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KAKDNLLK_00275 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
KAKDNLLK_00276 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KAKDNLLK_00277 1.69e-183 - - - K - - - transcriptional regulator, ArsR family
KAKDNLLK_00278 6.25e-220 abf - - G - - - Belongs to the glycosyl hydrolase 43 family
KAKDNLLK_00279 3.9e-276 lacY - - G ko:K02532 - ko00000,ko02000 Oligosaccharide H symporter
KAKDNLLK_00280 3.82e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
KAKDNLLK_00281 2.21e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KAKDNLLK_00282 8.55e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
KAKDNLLK_00283 4.7e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KAKDNLLK_00284 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
KAKDNLLK_00285 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
KAKDNLLK_00286 2.57e-309 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAKDNLLK_00287 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
KAKDNLLK_00288 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KAKDNLLK_00289 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAKDNLLK_00290 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAKDNLLK_00291 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAKDNLLK_00292 9.72e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAKDNLLK_00293 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAKDNLLK_00294 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAKDNLLK_00295 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KAKDNLLK_00296 1.97e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
KAKDNLLK_00297 6.99e-168 yibF - - S - - - overlaps another CDS with the same product name
KAKDNLLK_00298 7.83e-245 yibE - - S - - - overlaps another CDS with the same product name
KAKDNLLK_00299 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAKDNLLK_00300 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAKDNLLK_00301 2.47e-291 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAKDNLLK_00302 6.56e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KAKDNLLK_00303 4.42e-216 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KAKDNLLK_00304 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAKDNLLK_00305 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KAKDNLLK_00306 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
KAKDNLLK_00307 6.58e-162 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
KAKDNLLK_00308 2.67e-295 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
KAKDNLLK_00309 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KAKDNLLK_00310 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KAKDNLLK_00311 4.19e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
KAKDNLLK_00312 2.11e-251 ampC - - V - - - Beta-lactamase
KAKDNLLK_00313 5.04e-74 - - - - - - - -
KAKDNLLK_00314 0.0 - - - M - - - domain protein
KAKDNLLK_00315 5.35e-122 - - - - - - - -
KAKDNLLK_00317 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
KAKDNLLK_00318 1.28e-75 - - - - - - - -
KAKDNLLK_00320 9.38e-115 - - - - - - - -
KAKDNLLK_00321 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KAKDNLLK_00322 8.97e-65 - - - S - - - Cupredoxin-like domain
KAKDNLLK_00323 4.22e-69 - - - S - - - Cupredoxin-like domain
KAKDNLLK_00324 5.78e-133 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KAKDNLLK_00325 1.11e-206 - - - EG - - - EamA-like transporter family
KAKDNLLK_00326 7.95e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
KAKDNLLK_00327 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAKDNLLK_00328 1.51e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
KAKDNLLK_00329 0.0 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
KAKDNLLK_00330 1.07e-310 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
KAKDNLLK_00331 6.77e-26 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
KAKDNLLK_00333 2.69e-36 - - - - - - - -
KAKDNLLK_00334 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KAKDNLLK_00335 1.72e-153 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KAKDNLLK_00336 1.29e-198 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KAKDNLLK_00337 0.0 yclK - - T - - - Histidine kinase
KAKDNLLK_00338 4.67e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
KAKDNLLK_00340 2.27e-108 lytE - - M - - - Lysin motif
KAKDNLLK_00341 1.1e-190 - - - S - - - Cof-like hydrolase
KAKDNLLK_00342 5e-103 - - - K - - - Transcriptional regulator
KAKDNLLK_00343 0.0 oatA - - I - - - Acyltransferase
KAKDNLLK_00344 1.01e-67 - - - - - - - -
KAKDNLLK_00345 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KAKDNLLK_00346 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAKDNLLK_00347 1.06e-164 ybbR - - S - - - YbbR-like protein
KAKDNLLK_00348 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KAKDNLLK_00349 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
KAKDNLLK_00350 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KAKDNLLK_00351 6.2e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAKDNLLK_00352 1.94e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KAKDNLLK_00353 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KAKDNLLK_00354 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
KAKDNLLK_00355 6.2e-114 - - - K - - - Acetyltransferase (GNAT) domain
KAKDNLLK_00356 1.71e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
KAKDNLLK_00357 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KAKDNLLK_00358 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAKDNLLK_00359 7.9e-136 - - - - - - - -
KAKDNLLK_00360 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KAKDNLLK_00361 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KAKDNLLK_00362 6.92e-189 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
KAKDNLLK_00363 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KAKDNLLK_00364 0.0 eriC - - P ko:K03281 - ko00000 chloride
KAKDNLLK_00365 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
KAKDNLLK_00366 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KAKDNLLK_00367 1.02e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KAKDNLLK_00368 7.62e-290 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KAKDNLLK_00369 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KAKDNLLK_00371 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KAKDNLLK_00372 1.23e-309 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
KAKDNLLK_00373 1.83e-21 - - - - - - - -
KAKDNLLK_00375 1.94e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KAKDNLLK_00376 6.97e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KAKDNLLK_00377 8.05e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KAKDNLLK_00378 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
KAKDNLLK_00379 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KAKDNLLK_00380 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KAKDNLLK_00381 2.12e-19 - - - - - - - -
KAKDNLLK_00382 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
KAKDNLLK_00383 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KAKDNLLK_00384 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
KAKDNLLK_00385 1.15e-205 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
KAKDNLLK_00386 1.37e-270 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KAKDNLLK_00387 9.67e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KAKDNLLK_00388 6.21e-203 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
KAKDNLLK_00389 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
KAKDNLLK_00390 5.04e-175 lutC - - S ko:K00782 - ko00000 LUD domain
KAKDNLLK_00391 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KAKDNLLK_00392 7.73e-233 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KAKDNLLK_00393 1.03e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAKDNLLK_00394 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KAKDNLLK_00395 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KAKDNLLK_00396 3.65e-67 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
KAKDNLLK_00397 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAKDNLLK_00398 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KAKDNLLK_00399 1.13e-120 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAKDNLLK_00400 7.35e-150 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KAKDNLLK_00401 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
KAKDNLLK_00402 6.65e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KAKDNLLK_00403 1.58e-301 - - - EGP - - - Major Facilitator
KAKDNLLK_00404 3.07e-89 - - - K - - - Transcriptional regulator
KAKDNLLK_00405 2.63e-53 - - - - - - - -
KAKDNLLK_00406 0.0 ydaO - - E - - - amino acid
KAKDNLLK_00407 0.0 - - - E - - - amino acid
KAKDNLLK_00408 4.78e-110 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
KAKDNLLK_00409 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KAKDNLLK_00410 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAKDNLLK_00412 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KAKDNLLK_00413 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KAKDNLLK_00414 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_00415 0.0 - - - M - - - Rib/alpha-like repeat
KAKDNLLK_00416 0.0 - - - M - - - Rib/alpha-like repeat
KAKDNLLK_00417 6.83e-229 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAKDNLLK_00418 1.47e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KAKDNLLK_00419 6.08e-180 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
KAKDNLLK_00420 3.49e-175 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KAKDNLLK_00421 6.03e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAKDNLLK_00422 5.99e-169 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAKDNLLK_00423 1.01e-251 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAKDNLLK_00424 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
KAKDNLLK_00425 7.65e-164 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
KAKDNLLK_00426 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KAKDNLLK_00427 8.28e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KAKDNLLK_00428 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KAKDNLLK_00429 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KAKDNLLK_00430 6.09e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KAKDNLLK_00431 1.57e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAKDNLLK_00432 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
KAKDNLLK_00433 1.83e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KAKDNLLK_00434 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
KAKDNLLK_00435 6.4e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAKDNLLK_00436 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
KAKDNLLK_00437 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAKDNLLK_00438 3.4e-61 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAKDNLLK_00439 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KAKDNLLK_00440 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KAKDNLLK_00441 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KAKDNLLK_00442 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAKDNLLK_00443 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAKDNLLK_00444 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KAKDNLLK_00445 2.28e-170 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KAKDNLLK_00446 9.95e-107 - - - S - - - Protein of unknown function (DUF1700)
KAKDNLLK_00447 1.14e-74 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
KAKDNLLK_00448 1.2e-64 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KAKDNLLK_00450 2.39e-64 - - - - - - - -
KAKDNLLK_00451 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KAKDNLLK_00452 2.08e-106 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAKDNLLK_00453 4.59e-270 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KAKDNLLK_00454 1.14e-312 - - - M - - - Glycosyl transferase family group 2
KAKDNLLK_00456 3.22e-289 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
KAKDNLLK_00457 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KAKDNLLK_00458 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAKDNLLK_00459 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KAKDNLLK_00460 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KAKDNLLK_00461 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KAKDNLLK_00462 3.67e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAKDNLLK_00463 8.79e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KAKDNLLK_00464 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KAKDNLLK_00465 8.49e-265 yacL - - S - - - domain protein
KAKDNLLK_00466 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAKDNLLK_00467 1.63e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
KAKDNLLK_00468 3.89e-65 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
KAKDNLLK_00469 1.45e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAKDNLLK_00470 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KAKDNLLK_00471 4.99e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KAKDNLLK_00472 1.43e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00473 1.37e-153 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KAKDNLLK_00474 9e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KAKDNLLK_00475 6.27e-216 - - - I - - - alpha/beta hydrolase fold
KAKDNLLK_00476 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAKDNLLK_00477 0.0 - - - S - - - Bacterial membrane protein, YfhO
KAKDNLLK_00478 9.49e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
KAKDNLLK_00479 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
KAKDNLLK_00480 3.77e-193 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KAKDNLLK_00481 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KAKDNLLK_00482 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
KAKDNLLK_00484 1.12e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KAKDNLLK_00485 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
KAKDNLLK_00486 4.33e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KAKDNLLK_00487 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KAKDNLLK_00488 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
KAKDNLLK_00489 3.27e-167 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KAKDNLLK_00490 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
KAKDNLLK_00491 2.23e-315 - - - EGP - - - Major Facilitator
KAKDNLLK_00492 1.01e-141 - - - - - - - -
KAKDNLLK_00495 6.84e-189 - - - S - - - Calcineurin-like phosphoesterase
KAKDNLLK_00496 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
KAKDNLLK_00499 1.29e-21 - - - K - - - Cro/C1-type HTH DNA-binding domain
KAKDNLLK_00502 3.52e-58 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KAKDNLLK_00503 2.85e-268 - - - - - - - -
KAKDNLLK_00504 5.85e-33 - - - - - - - -
KAKDNLLK_00505 8.4e-188 - - - - - - - -
KAKDNLLK_00507 8.53e-53 - - - - - - - -
KAKDNLLK_00508 1.66e-15 - - - S - - - Phage-related holin (Lysis protein)
KAKDNLLK_00509 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAKDNLLK_00510 2.67e-47 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
KAKDNLLK_00512 1.35e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
KAKDNLLK_00513 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KAKDNLLK_00514 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KAKDNLLK_00515 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KAKDNLLK_00516 9.09e-260 camS - - S - - - sex pheromone
KAKDNLLK_00517 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAKDNLLK_00518 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KAKDNLLK_00519 4.61e-272 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KAKDNLLK_00520 4.76e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KAKDNLLK_00521 5.09e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
KAKDNLLK_00522 9.01e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
KAKDNLLK_00523 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KAKDNLLK_00524 3.77e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAKDNLLK_00525 1.5e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KAKDNLLK_00526 4.1e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAKDNLLK_00527 1.68e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAKDNLLK_00528 1.23e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAKDNLLK_00529 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KAKDNLLK_00530 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAKDNLLK_00531 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAKDNLLK_00532 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAKDNLLK_00533 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KAKDNLLK_00534 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAKDNLLK_00535 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KAKDNLLK_00536 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KAKDNLLK_00537 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KAKDNLLK_00538 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KAKDNLLK_00539 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAKDNLLK_00540 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAKDNLLK_00541 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAKDNLLK_00542 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAKDNLLK_00543 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAKDNLLK_00544 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAKDNLLK_00545 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KAKDNLLK_00546 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAKDNLLK_00547 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KAKDNLLK_00548 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAKDNLLK_00549 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAKDNLLK_00550 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAKDNLLK_00551 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAKDNLLK_00552 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAKDNLLK_00553 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KAKDNLLK_00554 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KAKDNLLK_00555 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAKDNLLK_00556 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KAKDNLLK_00557 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAKDNLLK_00558 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KAKDNLLK_00559 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAKDNLLK_00560 2.29e-152 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
KAKDNLLK_00561 2.96e-266 - - - - - - - -
KAKDNLLK_00562 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAKDNLLK_00563 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAKDNLLK_00564 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
KAKDNLLK_00565 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KAKDNLLK_00566 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KAKDNLLK_00567 5.17e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KAKDNLLK_00568 5.9e-232 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
KAKDNLLK_00569 4.07e-13 - - - - - - - -
KAKDNLLK_00570 2.91e-127 - - - L - - - Belongs to the 'phage' integrase family
KAKDNLLK_00574 7.75e-34 - - - S - - - FRG
KAKDNLLK_00575 5.4e-100 tnpR1 - - L - - - Resolvase, N terminal domain
KAKDNLLK_00582 1.81e-54 - - - D - - - nuclear chromosome segregation
KAKDNLLK_00583 6.89e-08 - - - K - - - Helix-turn-helix domain
KAKDNLLK_00588 1.99e-66 - - - - - - - -
KAKDNLLK_00589 1.06e-62 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KAKDNLLK_00591 2.86e-236 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KAKDNLLK_00597 1.29e-148 dgk2 - - F - - - deoxynucleoside kinase
KAKDNLLK_00598 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
KAKDNLLK_00599 1.59e-05 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KAKDNLLK_00600 6.58e-152 - - - I - - - phosphatase
KAKDNLLK_00601 1.06e-106 - - - S - - - Threonine/Serine exporter, ThrE
KAKDNLLK_00602 8.53e-166 - - - S - - - Putative threonine/serine exporter
KAKDNLLK_00603 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KAKDNLLK_00604 1.34e-160 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
KAKDNLLK_00605 4.92e-213 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KAKDNLLK_00606 1.27e-152 - - - S - - - membrane
KAKDNLLK_00607 5.5e-141 - - - S - - - VIT family
KAKDNLLK_00608 2.79e-107 - - - T - - - Belongs to the universal stress protein A family
KAKDNLLK_00609 1.14e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00610 1.34e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KAKDNLLK_00611 7.44e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KAKDNLLK_00612 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KAKDNLLK_00613 3.85e-280 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KAKDNLLK_00614 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KAKDNLLK_00615 1.92e-73 - - - - - - - -
KAKDNLLK_00616 8.85e-97 - - - K - - - MerR HTH family regulatory protein
KAKDNLLK_00617 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
KAKDNLLK_00618 2.6e-151 - - - S - - - Domain of unknown function (DUF4811)
KAKDNLLK_00619 1.31e-209 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KAKDNLLK_00621 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAKDNLLK_00622 6.46e-121 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KAKDNLLK_00623 8.44e-238 - - - I - - - Alpha beta
KAKDNLLK_00624 0.0 qacA - - EGP - - - Major Facilitator
KAKDNLLK_00625 8.7e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
KAKDNLLK_00626 0.0 - - - S - - - Putative threonine/serine exporter
KAKDNLLK_00627 7.21e-205 - - - K - - - LysR family
KAKDNLLK_00628 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KAKDNLLK_00629 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KAKDNLLK_00630 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KAKDNLLK_00631 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
KAKDNLLK_00632 5.85e-202 mleR - - K - - - LysR family
KAKDNLLK_00633 1.17e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAKDNLLK_00634 1.15e-264 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
KAKDNLLK_00635 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
KAKDNLLK_00636 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
KAKDNLLK_00639 6.92e-31 - - - - - - - -
KAKDNLLK_00640 7.41e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KAKDNLLK_00641 7.62e-97 - - - - - - - -
KAKDNLLK_00642 1.1e-279 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KAKDNLLK_00643 5.58e-178 - - - V - - - Beta-lactamase enzyme family
KAKDNLLK_00644 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
KAKDNLLK_00645 1.81e-274 - - - EGP - - - Transporter, major facilitator family protein
KAKDNLLK_00646 0.0 arcT - - E - - - Dipeptidase
KAKDNLLK_00647 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
KAKDNLLK_00648 2.59e-228 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
KAKDNLLK_00649 8.38e-216 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KAKDNLLK_00650 5.47e-176 - - - I - - - alpha/beta hydrolase fold
KAKDNLLK_00651 2.89e-230 - - - S - - - Conserved hypothetical protein 698
KAKDNLLK_00652 8.7e-123 - - - S - - - NADPH-dependent FMN reductase
KAKDNLLK_00653 7.92e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KAKDNLLK_00654 2.81e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KAKDNLLK_00655 1.09e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KAKDNLLK_00656 2.66e-114 - - - Q - - - Methyltransferase
KAKDNLLK_00657 3.26e-151 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
KAKDNLLK_00658 7.89e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
KAKDNLLK_00659 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KAKDNLLK_00660 2.31e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KAKDNLLK_00661 1.7e-284 - - - G - - - Glycosyl hydrolases family 8
KAKDNLLK_00662 6.09e-311 - - - M - - - Glycosyl transferase
KAKDNLLK_00663 1.9e-196 - - - - - - - -
KAKDNLLK_00664 3.02e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KAKDNLLK_00665 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KAKDNLLK_00666 7.4e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
KAKDNLLK_00667 3.93e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KAKDNLLK_00668 2.33e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KAKDNLLK_00669 2.92e-170 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
KAKDNLLK_00670 3.28e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KAKDNLLK_00671 9.97e-185 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KAKDNLLK_00672 2.14e-234 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
KAKDNLLK_00673 1.46e-96 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAKDNLLK_00674 2e-56 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAKDNLLK_00675 3.34e-209 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KAKDNLLK_00676 1.4e-145 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KAKDNLLK_00677 8.38e-170 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KAKDNLLK_00678 3.08e-102 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KAKDNLLK_00679 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
KAKDNLLK_00680 1.15e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
KAKDNLLK_00681 8.76e-63 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
KAKDNLLK_00682 1.03e-127 - - - S - - - AmiS/UreI family transporter
KAKDNLLK_00683 9.22e-287 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KAKDNLLK_00685 1.29e-235 - - - - - - - -
KAKDNLLK_00686 2.32e-126 - - - K - - - acetyltransferase
KAKDNLLK_00687 1.98e-141 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KAKDNLLK_00688 1.28e-117 lysR5 - - K - - - LysR substrate binding domain
KAKDNLLK_00689 3.1e-182 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KAKDNLLK_00690 3.43e-204 - - - K - - - LysR substrate binding domain
KAKDNLLK_00691 1.92e-264 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
KAKDNLLK_00692 1.22e-83 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAKDNLLK_00693 7.13e-223 - - - - - - - -
KAKDNLLK_00694 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAKDNLLK_00695 9.95e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KAKDNLLK_00696 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_00697 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_00698 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_00700 1.45e-200 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KAKDNLLK_00701 1.56e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KAKDNLLK_00702 1.9e-162 - - - O - - - Zinc-dependent metalloprotease
KAKDNLLK_00703 2.26e-149 - - - S - - - Membrane
KAKDNLLK_00704 1.18e-254 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KAKDNLLK_00705 9.19e-58 - - - - - - - -
KAKDNLLK_00706 2.6e-121 - - - S - - - Domain of unknown function (DUF4767)
KAKDNLLK_00707 3.7e-19 - - - - - - - -
KAKDNLLK_00708 5.71e-263 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
KAKDNLLK_00709 2.83e-121 - - - K - - - PFAM GCN5-related N-acetyltransferase
KAKDNLLK_00710 3.1e-217 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KAKDNLLK_00711 5.69e-105 - - - - - - - -
KAKDNLLK_00712 1.19e-161 - - - M - - - Lysin motif
KAKDNLLK_00713 6.71e-249 - - - EGP - - - Major Facilitator
KAKDNLLK_00714 6.03e-45 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
KAKDNLLK_00715 5.88e-72 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
KAKDNLLK_00716 1.59e-129 ywlG - - S - - - Belongs to the UPF0340 family
KAKDNLLK_00717 3.79e-123 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KAKDNLLK_00718 1.95e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAKDNLLK_00719 5.06e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KAKDNLLK_00720 3.22e-162 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
KAKDNLLK_00721 2.68e-129 - - - K - - - Cyclic nucleotide-binding domain
KAKDNLLK_00722 3.87e-164 - - - S - - - PFAM Archaeal ATPase
KAKDNLLK_00723 4.69e-203 - - - J - - - Methyltransferase
KAKDNLLK_00724 7.84e-284 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
KAKDNLLK_00725 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KAKDNLLK_00727 2.07e-280 - - - S ko:K07133 - ko00000 cog cog1373
KAKDNLLK_00728 6.84e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KAKDNLLK_00729 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KAKDNLLK_00730 6.71e-207 - - - EG - - - EamA-like transporter family
KAKDNLLK_00731 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KAKDNLLK_00732 1.9e-311 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KAKDNLLK_00733 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KAKDNLLK_00734 7.73e-147 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KAKDNLLK_00735 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase
KAKDNLLK_00736 1.49e-290 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAKDNLLK_00737 1.88e-14 - - - - - - - -
KAKDNLLK_00738 1.98e-42 - - - S - - - Transglycosylase associated protein
KAKDNLLK_00739 6.47e-10 - - - S - - - CsbD-like
KAKDNLLK_00740 1.39e-231 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAKDNLLK_00741 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
KAKDNLLK_00742 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
KAKDNLLK_00743 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
KAKDNLLK_00744 5.66e-194 - - - - - - - -
KAKDNLLK_00745 2.15e-37 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
KAKDNLLK_00746 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KAKDNLLK_00747 3.23e-133 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
KAKDNLLK_00748 1.46e-96 - - - F - - - Nudix hydrolase
KAKDNLLK_00749 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
KAKDNLLK_00750 9.37e-294 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KAKDNLLK_00751 2.92e-295 - - - - - - - -
KAKDNLLK_00752 1.21e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KAKDNLLK_00753 7.65e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KAKDNLLK_00754 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KAKDNLLK_00755 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KAKDNLLK_00756 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KAKDNLLK_00757 6.09e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KAKDNLLK_00758 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KAKDNLLK_00759 2.93e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KAKDNLLK_00760 0.0 yagE - - E - - - amino acid
KAKDNLLK_00761 1.29e-149 - - - S - - - HAD hydrolase, family IA, variant
KAKDNLLK_00763 1.74e-27 - - - S - - - PD-(D/E)XK nuclease family transposase
KAKDNLLK_00764 2.05e-197 - - - S - - - PD-(D/E)XK nuclease family transposase
KAKDNLLK_00766 4.01e-167 - - - S - - - PD-(D/E)XK nuclease family transposase
KAKDNLLK_00767 5.31e-27 - - - S - - - Domain of unknown function (DUF4767)
KAKDNLLK_00771 3.03e-05 - - - - - - - -
KAKDNLLK_00772 6.68e-147 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KAKDNLLK_00773 4.66e-194 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KAKDNLLK_00774 2.36e-107 - - - S - - - Double zinc ribbon
KAKDNLLK_00775 5.91e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KAKDNLLK_00776 6.65e-234 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
KAKDNLLK_00777 7.72e-178 - - - IQ - - - KR domain
KAKDNLLK_00778 5.13e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
KAKDNLLK_00779 1.81e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KAKDNLLK_00780 9.94e-316 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00781 7.15e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KAKDNLLK_00782 6.5e-71 - - - - - - - -
KAKDNLLK_00783 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
KAKDNLLK_00784 1.28e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KAKDNLLK_00785 1.78e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
KAKDNLLK_00786 1.3e-95 - - - K - - - Transcriptional regulator
KAKDNLLK_00787 1.35e-204 - - - - - - - -
KAKDNLLK_00788 6.32e-227 - - - C - - - Zinc-binding dehydrogenase
KAKDNLLK_00789 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
KAKDNLLK_00790 1.37e-270 - - - EGP - - - Major Facilitator
KAKDNLLK_00791 4.56e-175 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KAKDNLLK_00792 1.16e-151 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KAKDNLLK_00793 3.18e-11 - - - - - - - -
KAKDNLLK_00794 1.78e-83 - - - - - - - -
KAKDNLLK_00795 1.37e-246 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KAKDNLLK_00796 7.46e-106 uspA3 - - T - - - universal stress protein
KAKDNLLK_00797 0.0 fusA1 - - J - - - elongation factor G
KAKDNLLK_00798 7.59e-214 - - - GK - - - ROK family
KAKDNLLK_00799 3.4e-311 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KAKDNLLK_00800 2.23e-180 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
KAKDNLLK_00801 2.13e-310 - - - E - - - amino acid
KAKDNLLK_00802 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KAKDNLLK_00803 5.23e-172 gntR - - K - - - UbiC transcription regulator-associated domain protein
KAKDNLLK_00804 1.93e-112 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAKDNLLK_00805 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KAKDNLLK_00806 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
KAKDNLLK_00807 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00808 1.65e-241 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAKDNLLK_00809 4.13e-116 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
KAKDNLLK_00810 3.57e-81 - - - S - - - Domain of unknown function (DUF4430)
KAKDNLLK_00811 1.6e-247 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
KAKDNLLK_00812 3.41e-169 - - - H - - - Uroporphyrinogen-III synthase
KAKDNLLK_00813 3.23e-145 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
KAKDNLLK_00814 1.74e-175 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KAKDNLLK_00815 1.47e-132 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
KAKDNLLK_00816 0.0 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
KAKDNLLK_00817 8.06e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
KAKDNLLK_00818 1.42e-216 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KAKDNLLK_00819 3.46e-303 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KAKDNLLK_00820 9.88e-105 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
KAKDNLLK_00821 0.0 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
KAKDNLLK_00822 1.24e-191 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
KAKDNLLK_00823 1.43e-151 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KAKDNLLK_00824 2.56e-70 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KAKDNLLK_00825 4.44e-171 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KAKDNLLK_00826 2.2e-161 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
KAKDNLLK_00827 1.51e-188 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
KAKDNLLK_00828 0.0 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
KAKDNLLK_00829 3.97e-176 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
KAKDNLLK_00830 5.23e-171 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
KAKDNLLK_00831 1.55e-250 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
KAKDNLLK_00832 3.02e-176 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
KAKDNLLK_00833 2.57e-127 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
KAKDNLLK_00834 4.22e-143 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
KAKDNLLK_00835 8.23e-269 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KAKDNLLK_00836 6.88e-160 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
KAKDNLLK_00837 1.17e-222 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KAKDNLLK_00838 0.0 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
KAKDNLLK_00839 7.56e-266 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
KAKDNLLK_00840 1.37e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
KAKDNLLK_00841 1.03e-201 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
KAKDNLLK_00842 6.23e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KAKDNLLK_00843 2.69e-95 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
KAKDNLLK_00844 5.79e-120 - - - P - - - Cadmium resistance transporter
KAKDNLLK_00845 4.9e-158 pgm1 - - G - - - phosphoglycerate mutase
KAKDNLLK_00846 1.7e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
KAKDNLLK_00847 3.32e-74 - - - E ko:K04031 - ko00000 BMC
KAKDNLLK_00848 1.3e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAKDNLLK_00849 6.52e-270 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
KAKDNLLK_00850 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
KAKDNLLK_00851 1.01e-104 pduO - - S - - - Haem-degrading
KAKDNLLK_00852 1.26e-137 - - - S - - - Cobalamin adenosyltransferase
KAKDNLLK_00853 1.96e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
KAKDNLLK_00854 2.75e-116 - - - S - - - Putative propanediol utilisation
KAKDNLLK_00855 1.77e-151 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
KAKDNLLK_00856 4.11e-57 pduA_2 - - CQ ko:K04027 - ko00000 BMC
KAKDNLLK_00857 1.02e-115 - - - CQ - - - BMC
KAKDNLLK_00858 2.04e-79 pduH - - S - - - Dehydratase medium subunit
KAKDNLLK_00859 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
KAKDNLLK_00860 4.15e-111 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
KAKDNLLK_00861 1.33e-166 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
KAKDNLLK_00862 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
KAKDNLLK_00863 3.41e-170 pduB - - E - - - BMC
KAKDNLLK_00864 2.72e-56 - - - CQ - - - BMC
KAKDNLLK_00865 1.69e-258 - - - K - - - helix_turn_helix, arabinose operon control protein
KAKDNLLK_00866 4.65e-192 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
KAKDNLLK_00867 4.17e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KAKDNLLK_00868 1.22e-206 - - - - - - - -
KAKDNLLK_00869 7.79e-197 - - - G - - - Xylose isomerase domain protein TIM barrel
KAKDNLLK_00870 2.7e-241 XK27_12525 - - S - - - AI-2E family transporter
KAKDNLLK_00871 7.74e-173 XK27_07210 - - S - - - B3 4 domain
KAKDNLLK_00872 3.33e-102 yybA - - K - - - Transcriptional regulator
KAKDNLLK_00873 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
KAKDNLLK_00874 2.93e-119 - - - GM - - - epimerase
KAKDNLLK_00875 1.51e-202 - - - V - - - (ABC) transporter
KAKDNLLK_00876 4.96e-308 yhdP - - S - - - Transporter associated domain
KAKDNLLK_00877 4e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
KAKDNLLK_00878 3.68e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
KAKDNLLK_00879 3.75e-246 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
KAKDNLLK_00880 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KAKDNLLK_00881 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KAKDNLLK_00882 7.15e-54 - - - - - - - -
KAKDNLLK_00883 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KAKDNLLK_00884 1.69e-163 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
KAKDNLLK_00885 6.65e-104 usp5 - - T - - - universal stress protein
KAKDNLLK_00886 8.05e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
KAKDNLLK_00887 1.76e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KAKDNLLK_00888 9.47e-137 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
KAKDNLLK_00889 1.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KAKDNLLK_00890 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KAKDNLLK_00891 1.03e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAKDNLLK_00892 1.44e-229 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
KAKDNLLK_00893 8.08e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KAKDNLLK_00894 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KAKDNLLK_00895 1.21e-48 - - - - - - - -
KAKDNLLK_00896 1.76e-68 - - - - - - - -
KAKDNLLK_00897 1.29e-260 - - - - - - - -
KAKDNLLK_00898 4.74e-107 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KAKDNLLK_00899 8.01e-175 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KAKDNLLK_00900 6.94e-200 yvgN - - S - - - Aldo keto reductase
KAKDNLLK_00901 6.16e-161 XK27_10500 - - K - - - response regulator
KAKDNLLK_00902 3.55e-232 kinG - - T - - - Histidine kinase-like ATPases
KAKDNLLK_00903 4.29e-175 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00904 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KAKDNLLK_00905 1.2e-202 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KAKDNLLK_00906 1.59e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KAKDNLLK_00907 1.97e-69 - - - K - - - helix_turn_helix, mercury resistance
KAKDNLLK_00908 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAKDNLLK_00909 3.12e-254 - - - EGP - - - Major Facilitator
KAKDNLLK_00910 3.21e-115 ymdB - - S - - - Macro domain protein
KAKDNLLK_00911 2.61e-140 - - - K - - - Helix-turn-helix XRE-family like proteins
KAKDNLLK_00912 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KAKDNLLK_00913 5.79e-62 - - - - - - - -
KAKDNLLK_00914 5.5e-300 - - - S - - - Putative metallopeptidase domain
KAKDNLLK_00915 2.25e-265 - - - S - - - associated with various cellular activities
KAKDNLLK_00916 1.92e-153 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KAKDNLLK_00917 4.53e-85 yeaO - - S - - - Protein of unknown function, DUF488
KAKDNLLK_00919 2.28e-149 yrkL - - S - - - Flavodoxin-like fold
KAKDNLLK_00920 5.52e-71 - - - - - - - -
KAKDNLLK_00922 6.77e-173 - 2.1.1.72 - D ko:K03427 - ko00000,ko01000,ko02048 peptidase
KAKDNLLK_00923 3.53e-66 - - - - - - - -
KAKDNLLK_00927 5.99e-17 - - - K - - - Helix-turn-helix domain
KAKDNLLK_00929 1.45e-259 yngD - - S ko:K07097 - ko00000 DHHA1 domain
KAKDNLLK_00930 2.12e-292 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
KAKDNLLK_00931 9.02e-317 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KAKDNLLK_00932 7.28e-138 - - - NU - - - mannosyl-glycoprotein
KAKDNLLK_00933 3.98e-184 - - - S - - - Putative ABC-transporter type IV
KAKDNLLK_00934 0.0 - - - S - - - ABC transporter, ATP-binding protein
KAKDNLLK_00935 4.8e-19 XK27_09155 - - K - - - Transcriptional
KAKDNLLK_00936 4.44e-62 - - - L - - - Integrase
KAKDNLLK_00937 1.28e-41 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
KAKDNLLK_00938 1.01e-133 - - - S - - - Protein of unknown function (DUF3278)
KAKDNLLK_00941 2.21e-27 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
KAKDNLLK_00942 7.97e-49 - - - M - - - Sortase family
KAKDNLLK_00943 1.6e-93 - - - K - - - Transcriptional regulator, TetR family
KAKDNLLK_00944 2.09e-162 - - - M - - - PFAM NLP P60 protein
KAKDNLLK_00945 7.76e-234 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KAKDNLLK_00946 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KAKDNLLK_00947 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00948 2.63e-117 - - - P - - - Cadmium resistance transporter
KAKDNLLK_00949 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
KAKDNLLK_00950 3.34e-91 - - - M - - - domain protein
KAKDNLLK_00951 2.64e-303 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
KAKDNLLK_00952 6.22e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KAKDNLLK_00953 5.37e-169 yceF - - P ko:K05794 - ko00000 membrane
KAKDNLLK_00954 6.7e-211 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KAKDNLLK_00955 2.75e-214 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KAKDNLLK_00956 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KAKDNLLK_00957 9.66e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KAKDNLLK_00958 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KAKDNLLK_00959 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
KAKDNLLK_00960 1.64e-162 pgm3 - - G - - - phosphoglycerate mutase family
KAKDNLLK_00961 7.2e-56 - - - - - - - -
KAKDNLLK_00962 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KAKDNLLK_00963 9.99e-45 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAKDNLLK_00964 2.19e-135 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KAKDNLLK_00965 3.58e-199 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KAKDNLLK_00966 7.88e-46 - - - - - - - -
KAKDNLLK_00967 2.34e-202 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAKDNLLK_00968 1.41e-15 - - - G - - - Major Facilitator
KAKDNLLK_00969 4.45e-67 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KAKDNLLK_00970 4.16e-161 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAKDNLLK_00971 4.17e-165 - - - G - - - Major Facilitator Superfamily
KAKDNLLK_00972 8.15e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
KAKDNLLK_00973 4.06e-185 - - - S - - - Alpha beta hydrolase
KAKDNLLK_00974 4.64e-276 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KAKDNLLK_00975 1.36e-131 - - - - - - - -
KAKDNLLK_00977 2.94e-161 - - - M - - - ErfK YbiS YcfS YnhG
KAKDNLLK_00978 0.0 - - - S - - - Putative peptidoglycan binding domain
KAKDNLLK_00979 7.44e-143 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KAKDNLLK_00980 6.28e-116 - - - - - - - -
KAKDNLLK_00981 5.61e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KAKDNLLK_00982 2.12e-274 yttB - - EGP - - - Major Facilitator
KAKDNLLK_00983 5.96e-146 - - - - - - - -
KAKDNLLK_00984 2.6e-33 - - - - - - - -
KAKDNLLK_00985 4.41e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
KAKDNLLK_00986 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KAKDNLLK_00987 1.36e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
KAKDNLLK_00988 3.38e-50 - - - - - - - -
KAKDNLLK_00989 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00990 4.99e-154 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_00991 6.85e-234 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KAKDNLLK_00992 6.45e-114 - - - K - - - transcriptional regulator (TetR family)
KAKDNLLK_00993 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
KAKDNLLK_00994 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KAKDNLLK_00995 4.17e-72 - - - - - - - -
KAKDNLLK_00996 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAKDNLLK_00998 4.44e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
KAKDNLLK_00999 2.14e-315 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
KAKDNLLK_01000 9.08e-317 - - - E ko:K03294 - ko00000 amino acid
KAKDNLLK_01001 1.15e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KAKDNLLK_01003 3.88e-38 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KAKDNLLK_01004 0.000126 - - - S - - - Protein of unknown function (DUF3278)
KAKDNLLK_01005 1.37e-269 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
KAKDNLLK_01006 5.47e-55 - - - S - - - Cytochrome B5
KAKDNLLK_01007 8.47e-08 - - - S - - - Cytochrome B5
KAKDNLLK_01008 2.3e-52 - - - S - - - Cytochrome B5
KAKDNLLK_01009 2.46e-97 - - - S ko:K02348 - ko00000 Gnat family
KAKDNLLK_01010 3.17e-156 - - - GM - - - NmrA-like family
KAKDNLLK_01011 3.2e-68 ydeP - - K - - - Transcriptional regulator, HxlR family
KAKDNLLK_01012 3.89e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
KAKDNLLK_01013 1.85e-108 - - - K - - - Transcriptional regulator, HxlR family
KAKDNLLK_01014 2.23e-298 - - - - - - - -
KAKDNLLK_01015 1.79e-267 - - - EGP - - - Major Facilitator Superfamily
KAKDNLLK_01016 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KAKDNLLK_01017 1.19e-144 - - - GM - - - NAD dependent epimerase dehydratase family protein
KAKDNLLK_01018 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KAKDNLLK_01019 5.35e-121 - - - S - - - ECF transporter, substrate-specific component
KAKDNLLK_01020 2.47e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KAKDNLLK_01021 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KAKDNLLK_01022 1.24e-158 - - - T - - - Putative diguanylate phosphodiesterase
KAKDNLLK_01023 4.92e-254 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
KAKDNLLK_01024 4.4e-112 - - - - - - - -
KAKDNLLK_01025 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
KAKDNLLK_01026 1.06e-180 - - - T - - - EAL domain
KAKDNLLK_01027 4.51e-163 - - - F - - - glutamine amidotransferase
KAKDNLLK_01028 6.81e-83 - - - - - - - -
KAKDNLLK_01029 5.01e-142 - - - GM - - - NAD(P)H-binding
KAKDNLLK_01030 1.21e-248 - - - S - - - membrane
KAKDNLLK_01031 1.31e-133 - - - K - - - Transcriptional regulator C-terminal region
KAKDNLLK_01032 1.64e-204 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KAKDNLLK_01033 1.42e-188 - - - K - - - Transcriptional regulator
KAKDNLLK_01034 5.69e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
KAKDNLLK_01035 1.76e-215 ypuA - - S - - - Protein of unknown function (DUF1002)
KAKDNLLK_01036 3.41e-84 - - - GM - - - NAD(P)H-binding
KAKDNLLK_01037 3.67e-114 - - - K - - - Virulence activator alpha C-term
KAKDNLLK_01038 6.12e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
KAKDNLLK_01039 2.79e-193 - - - S - - - Alpha beta hydrolase
KAKDNLLK_01040 3.98e-173 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
KAKDNLLK_01041 8.66e-113 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KAKDNLLK_01042 1.22e-189 lysR - - K - - - Transcriptional regulator
KAKDNLLK_01043 3.82e-33 - - - - - - - -
KAKDNLLK_01044 2.57e-109 - - - C - - - Flavodoxin
KAKDNLLK_01045 6.75e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
KAKDNLLK_01046 9.46e-38 - - - - - - - -
KAKDNLLK_01047 1.66e-17 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KAKDNLLK_01048 3.45e-112 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
KAKDNLLK_01049 1.72e-207 - - - C - - - nadph quinone reductase
KAKDNLLK_01050 1.64e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
KAKDNLLK_01051 9.36e-143 - - - M - - - Protein of unknown function (DUF3737)
KAKDNLLK_01052 1.63e-281 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KAKDNLLK_01053 2.68e-161 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
KAKDNLLK_01054 9.02e-168 yneE - - K - - - Transcriptional regulator
KAKDNLLK_01055 9.9e-118 - - - S - - - Peptidase propeptide and YPEB domain
KAKDNLLK_01056 1.24e-298 - - - T - - - GHKL domain
KAKDNLLK_01057 4.82e-155 - - - T - - - Transcriptional regulatory protein, C terminal
KAKDNLLK_01058 2.77e-66 rmaD - - K - - - transcriptional
KAKDNLLK_01059 8.68e-136 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KAKDNLLK_01060 7.76e-207 - - - S ko:K07088 - ko00000 Membrane transport protein
KAKDNLLK_01061 1.23e-152 - - - H - - - RibD C-terminal domain
KAKDNLLK_01066 1.41e-250 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KAKDNLLK_01067 5.11e-155 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KAKDNLLK_01068 1.94e-16 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KAKDNLLK_01069 8.36e-26 - - - H - - - RibD C-terminal domain
KAKDNLLK_01070 9.98e-24 - - - - - - - -
KAKDNLLK_01071 9.81e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
KAKDNLLK_01072 3.11e-116 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
KAKDNLLK_01073 2.31e-73 - - - S - - - Antibiotic biosynthesis monooxygenase
KAKDNLLK_01074 7.36e-250 flp - - V - - - Beta-lactamase
KAKDNLLK_01075 4.31e-123 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KAKDNLLK_01076 3.56e-161 - - - S ko:K07507 - ko00000,ko02000 MgtC family
KAKDNLLK_01077 8.78e-150 - - - S - - - GyrI-like small molecule binding domain
KAKDNLLK_01078 1.74e-164 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KAKDNLLK_01079 4.47e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KAKDNLLK_01080 1.07e-137 - - - K - - - Bacterial regulatory proteins, tetR family
KAKDNLLK_01081 6.35e-214 - - - C - - - Aldo/keto reductase family
KAKDNLLK_01082 2.9e-123 - - - K - - - Transcriptional regulator
KAKDNLLK_01083 9.14e-146 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KAKDNLLK_01084 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
KAKDNLLK_01085 2.67e-154 azlC - - E - - - azaleucine resistance protein AzlC
KAKDNLLK_01086 0.0 - - - K - - - Aminotransferase class I and II
KAKDNLLK_01087 1.73e-05 - - - K - - - helix_turn_helix, arabinose operon control protein
KAKDNLLK_01088 6.86e-48 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Metal binding domain of Ada
KAKDNLLK_01089 3.84e-60 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KAKDNLLK_01090 0.0 - - - S - - - amidohydrolase
KAKDNLLK_01091 1.48e-161 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KAKDNLLK_01092 1.96e-185 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KAKDNLLK_01094 1.35e-205 - - - S - - - reductase
KAKDNLLK_01095 1.73e-118 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
KAKDNLLK_01096 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KAKDNLLK_01097 7.33e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
KAKDNLLK_01098 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAKDNLLK_01099 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KAKDNLLK_01100 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KAKDNLLK_01101 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAKDNLLK_01102 2.28e-172 jag - - S ko:K06346 - ko00000 R3H domain protein
KAKDNLLK_01103 8.5e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KAKDNLLK_01104 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KAKDNLLK_01105 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KAKDNLLK_01106 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAKDNLLK_01107 2e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KAKDNLLK_01108 2.11e-161 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
KAKDNLLK_01109 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
KAKDNLLK_01110 2.95e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAKDNLLK_01111 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KAKDNLLK_01112 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KAKDNLLK_01113 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KAKDNLLK_01114 1.03e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KAKDNLLK_01115 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAKDNLLK_01116 4.27e-124 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAKDNLLK_01117 1.49e-129 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
KAKDNLLK_01118 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KAKDNLLK_01119 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KAKDNLLK_01120 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KAKDNLLK_01121 4.39e-268 yttB - - EGP - - - Major Facilitator
KAKDNLLK_01122 6.12e-78 - - - - - - - -
KAKDNLLK_01123 2.17e-209 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
KAKDNLLK_01124 1.43e-129 - - - K - - - DNA-binding helix-turn-helix protein
KAKDNLLK_01126 2.67e-96 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
KAKDNLLK_01127 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
KAKDNLLK_01129 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KAKDNLLK_01130 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KAKDNLLK_01131 0.0 yycH - - S - - - YycH protein
KAKDNLLK_01132 5.03e-193 yycI - - S - - - YycH protein
KAKDNLLK_01133 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
KAKDNLLK_01134 8.22e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
KAKDNLLK_01135 1.79e-111 pgpA - - I - - - Phosphatidylglycerophosphatase A
KAKDNLLK_01136 3.81e-228 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KAKDNLLK_01137 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAKDNLLK_01139 9.06e-125 - - - S - - - reductase
KAKDNLLK_01140 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
KAKDNLLK_01141 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KAKDNLLK_01142 5.08e-191 - - - E - - - Glyoxalase-like domain
KAKDNLLK_01143 3.03e-189 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAKDNLLK_01144 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KAKDNLLK_01145 1.17e-199 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAKDNLLK_01146 4.85e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KAKDNLLK_01147 1.53e-269 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KAKDNLLK_01149 2.08e-69 - - - - - - - -
KAKDNLLK_01150 4.51e-64 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KAKDNLLK_01151 3.2e-291 - - - S - - - Putative peptidoglycan binding domain
KAKDNLLK_01154 4.83e-249 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KAKDNLLK_01155 2.71e-160 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KAKDNLLK_01157 2.94e-304 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KAKDNLLK_01159 6.86e-98 - - - O - - - OsmC-like protein
KAKDNLLK_01160 2.55e-223 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAKDNLLK_01161 1.01e-275 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KAKDNLLK_01162 8.68e-44 - - - - - - - -
KAKDNLLK_01163 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
KAKDNLLK_01165 4.07e-138 - - - K - - - PFAM GCN5-related N-acetyltransferase
KAKDNLLK_01166 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAKDNLLK_01167 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KAKDNLLK_01168 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KAKDNLLK_01169 1.05e-221 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KAKDNLLK_01170 6.46e-266 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KAKDNLLK_01171 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KAKDNLLK_01172 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KAKDNLLK_01173 5.89e-153 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KAKDNLLK_01174 1.4e-90 - - - - - - - -
KAKDNLLK_01175 1.24e-112 - - - T - - - Region found in RelA / SpoT proteins
KAKDNLLK_01176 2.48e-150 dltr - - K - - - response regulator
KAKDNLLK_01177 1.47e-285 sptS - - T - - - Histidine kinase
KAKDNLLK_01178 4.71e-264 - - - P - - - Voltage gated chloride channel
KAKDNLLK_01179 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KAKDNLLK_01180 3.7e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
KAKDNLLK_01181 1.48e-214 - - - C - - - Aldo keto reductase
KAKDNLLK_01182 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
KAKDNLLK_01183 9.24e-114 - - - S - - - ECF-type riboflavin transporter, S component
KAKDNLLK_01184 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
KAKDNLLK_01185 1.2e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KAKDNLLK_01186 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAKDNLLK_01187 8.91e-122 - - - - - - - -
KAKDNLLK_01188 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KAKDNLLK_01190 6.88e-144 - - - K - - - Transcriptional regulator, TetR family
KAKDNLLK_01191 9.59e-92 - - - - - - - -
KAKDNLLK_01192 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KAKDNLLK_01193 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
KAKDNLLK_01194 0.0 - - - M - - - domain protein
KAKDNLLK_01195 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KAKDNLLK_01196 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KAKDNLLK_01197 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KAKDNLLK_01198 1.11e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KAKDNLLK_01199 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KAKDNLLK_01200 2.21e-231 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
KAKDNLLK_01201 1.01e-63 - - - K - - - LysR substrate binding domain
KAKDNLLK_01202 1.93e-235 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KAKDNLLK_01203 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAKDNLLK_01205 2.19e-131 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
KAKDNLLK_01206 6.05e-274 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
KAKDNLLK_01207 4.65e-228 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KAKDNLLK_01208 9.07e-59 - - - K - - - Bacterial regulatory proteins, tetR family
KAKDNLLK_01209 2.62e-270 - - - EGP - - - Major Facilitator
KAKDNLLK_01210 1.5e-86 yjdF3 - - S - - - Protein of unknown function (DUF2992)
KAKDNLLK_01211 7.91e-42 - - - K - - - Psort location Cytoplasmic, score
KAKDNLLK_01212 8.57e-114 entB - - Q - - - Isochorismatase family
KAKDNLLK_01213 2.05e-121 - - - K - - - Bacterial regulatory proteins, tetR family
KAKDNLLK_01214 1e-138 - - - S - - - NADPH-dependent FMN reductase
KAKDNLLK_01215 1.56e-310 - - - EGP - - - Major Facilitator
KAKDNLLK_01216 6.66e-113 padR - - K - - - Transcriptional regulator PadR-like family
KAKDNLLK_01217 2.48e-76 - - - H - - - Riboflavin biosynthesis protein RibD
KAKDNLLK_01218 5.34e-248 - - - S - - - PFAM Archaeal ATPase
KAKDNLLK_01219 2.04e-57 - - - - - - - -
KAKDNLLK_01221 1.46e-112 - - - S - - - PD-(D/E)XK nuclease family transposase
KAKDNLLK_01222 8.89e-269 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KAKDNLLK_01223 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
KAKDNLLK_01224 3.15e-119 XK27_07210 - - S - - - B3 4 domain
KAKDNLLK_01225 1.48e-207 - - - P - - - Belongs to the major facilitator superfamily
KAKDNLLK_01226 1.5e-119 - - - - - - - -
KAKDNLLK_01227 3.57e-157 pnb - - C - - - nitroreductase
KAKDNLLK_01228 4.76e-217 XK27_00915 - - C - - - Luciferase-like monooxygenase
KAKDNLLK_01229 5.01e-55 - - - K - - - helix_turn_helix, mercury resistance
KAKDNLLK_01230 1.41e-39 - - - S - - - NAD(P)H dehydrogenase (quinone) activity
KAKDNLLK_01231 1.13e-143 - - - S - - - X-Pro dipeptidyl-peptidase (S15 family)
KAKDNLLK_01232 2.2e-50 - 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NAD(P)H dehydrogenase (quinone) activity
KAKDNLLK_01233 9.59e-216 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
KAKDNLLK_01234 1.79e-96 - - - S - - - Protein of unknown function (DUF3021)
KAKDNLLK_01235 1.22e-101 - - - K - - - LytTr DNA-binding domain
KAKDNLLK_01236 7.24e-120 - - - K - - - Acetyltransferase (GNAT) family
KAKDNLLK_01237 1.1e-26 - - - - - - - -
KAKDNLLK_01238 6.4e-260 - - - P - - - Major Facilitator Superfamily
KAKDNLLK_01239 1.86e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KAKDNLLK_01240 6.2e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
KAKDNLLK_01241 9.2e-247 - - - S - - - Protein of unknown function (DUF3114)
KAKDNLLK_01242 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KAKDNLLK_01243 3.08e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KAKDNLLK_01244 4.36e-137 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KAKDNLLK_01245 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
KAKDNLLK_01246 5.34e-245 mocA - - S - - - Oxidoreductase
KAKDNLLK_01247 1.1e-296 yfmL - - L - - - DEAD DEAH box helicase
KAKDNLLK_01249 1.47e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KAKDNLLK_01250 8.59e-98 gtcA - - S - - - Teichoic acid glycosylation protein
KAKDNLLK_01251 2.72e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KAKDNLLK_01252 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
KAKDNLLK_01253 5.66e-280 arcT - - E - - - Aminotransferase
KAKDNLLK_01254 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KAKDNLLK_01255 0.0 potE - - E - - - Amino Acid
KAKDNLLK_01256 2.05e-200 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KAKDNLLK_01257 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
KAKDNLLK_01258 7.27e-42 - - - - - - - -
KAKDNLLK_01259 5.78e-175 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KAKDNLLK_01260 8.11e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
KAKDNLLK_01261 2.67e-223 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KAKDNLLK_01262 5.7e-153 - - - M - - - Bacterial sugar transferase
KAKDNLLK_01263 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
KAKDNLLK_01275 4.84e-144 - - - I - - - Acid phosphatase homologues
KAKDNLLK_01276 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
KAKDNLLK_01277 1.44e-294 - - - P - - - Chloride transporter, ClC family
KAKDNLLK_01280 1.97e-169 - - - F - - - NUDIX domain
KAKDNLLK_01281 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KAKDNLLK_01282 1.19e-131 pncA - - Q - - - Isochorismatase family
KAKDNLLK_01283 3.74e-229 - - - O - - - ADP-ribosylglycohydrolase
KAKDNLLK_01284 2.03e-78 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
KAKDNLLK_01285 7.6e-117 - - - L - - - PFAM Integrase catalytic region
KAKDNLLK_01286 3.51e-308 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
KAKDNLLK_01287 2.11e-168 - - - IQ - - - dehydrogenase reductase
KAKDNLLK_01288 4.54e-49 - - - - - - - -
KAKDNLLK_01289 6.62e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
KAKDNLLK_01290 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
KAKDNLLK_01291 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KAKDNLLK_01292 9.76e-233 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KAKDNLLK_01294 1.39e-129 - - - S ko:K07002 - ko00000 Serine hydrolase
KAKDNLLK_01295 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
KAKDNLLK_01296 8.69e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KAKDNLLK_01298 5.2e-225 ydhF - - S - - - Aldo keto reductase
KAKDNLLK_01299 2.53e-107 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
KAKDNLLK_01300 0.0 - - - L - - - Helicase C-terminal domain protein
KAKDNLLK_01302 1.23e-309 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
KAKDNLLK_01303 2.73e-71 - - - S - - - Sugar efflux transporter for intercellular exchange
KAKDNLLK_01304 9.01e-164 - - - - - - - -
KAKDNLLK_01305 2.76e-163 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KAKDNLLK_01306 0.0 cadA - - P - - - P-type ATPase
KAKDNLLK_01307 1.31e-287 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
KAKDNLLK_01308 4.44e-11 - - - - - - - -
KAKDNLLK_01309 6.66e-200 - - - GM - - - NAD(P)H-binding
KAKDNLLK_01310 4.7e-98 ywnA - - K - - - Transcriptional regulator
KAKDNLLK_01311 8.79e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
KAKDNLLK_01312 2.35e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KAKDNLLK_01313 1.06e-182 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_01314 2.29e-137 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
KAKDNLLK_01315 2.05e-99 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KAKDNLLK_01316 0.0 eriC - - P ko:K03281 - ko00000 chloride
KAKDNLLK_01317 6.12e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KAKDNLLK_01318 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KAKDNLLK_01319 8.52e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAKDNLLK_01320 6.16e-200 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KAKDNLLK_01321 1.47e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KAKDNLLK_01322 5.93e-281 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
KAKDNLLK_01323 1.3e-58 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
KAKDNLLK_01324 1.99e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAKDNLLK_01325 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
KAKDNLLK_01326 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KAKDNLLK_01328 3.16e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KAKDNLLK_01329 0.0 - - - L - - - DNA helicase
KAKDNLLK_01330 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
KAKDNLLK_01331 6.41e-236 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
KAKDNLLK_01332 3.2e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KAKDNLLK_01333 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KAKDNLLK_01334 1.12e-287 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KAKDNLLK_01335 2.21e-227 - - - - - - - -
KAKDNLLK_01336 6.9e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
KAKDNLLK_01338 6.46e-206 yunF - - F - - - Protein of unknown function DUF72
KAKDNLLK_01339 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAKDNLLK_01340 5.93e-197 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
KAKDNLLK_01341 8.57e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KAKDNLLK_01342 7.22e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KAKDNLLK_01343 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
KAKDNLLK_01344 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KAKDNLLK_01345 1.66e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KAKDNLLK_01346 4.85e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KAKDNLLK_01347 8.69e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
KAKDNLLK_01348 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KAKDNLLK_01349 4.57e-316 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAKDNLLK_01350 5.85e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAKDNLLK_01351 1.96e-101 - - - - - - - -
KAKDNLLK_01352 1.67e-258 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KAKDNLLK_01353 1.56e-188 yidA - - S - - - hydrolase
KAKDNLLK_01354 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
KAKDNLLK_01355 2.71e-194 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
KAKDNLLK_01356 3.15e-71 ywiB - - S - - - Domain of unknown function (DUF1934)
KAKDNLLK_01357 2.68e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KAKDNLLK_01358 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KAKDNLLK_01359 9.55e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAKDNLLK_01360 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KAKDNLLK_01361 7.55e-302 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KAKDNLLK_01362 5.56e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KAKDNLLK_01363 1.23e-161 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
KAKDNLLK_01364 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KAKDNLLK_01365 1.84e-192 - - - G - - - Right handed beta helix region
KAKDNLLK_01366 1.43e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KAKDNLLK_01367 5.32e-208 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
KAKDNLLK_01368 2.14e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
KAKDNLLK_01369 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAKDNLLK_01370 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
KAKDNLLK_01371 2.61e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KAKDNLLK_01372 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KAKDNLLK_01373 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KAKDNLLK_01374 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
KAKDNLLK_01375 7.06e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KAKDNLLK_01376 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KAKDNLLK_01377 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KAKDNLLK_01378 1.57e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
KAKDNLLK_01379 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KAKDNLLK_01380 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
KAKDNLLK_01381 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KAKDNLLK_01382 4.41e-269 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAKDNLLK_01383 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KAKDNLLK_01384 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
KAKDNLLK_01385 2.1e-309 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
KAKDNLLK_01386 5.9e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
KAKDNLLK_01387 2.32e-146 - - - S - - - (CBS) domain
KAKDNLLK_01388 7.67e-190 - - - - - - - -
KAKDNLLK_01390 1.13e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KAKDNLLK_01391 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAKDNLLK_01392 4.11e-52 yabO - - J - - - S4 domain protein
KAKDNLLK_01393 2.49e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KAKDNLLK_01394 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
KAKDNLLK_01395 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KAKDNLLK_01396 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KAKDNLLK_01397 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAKDNLLK_01398 2.27e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAKDNLLK_01399 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAKDNLLK_01400 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KAKDNLLK_01401 3.8e-112 - - - - - - - -
KAKDNLLK_01403 5.91e-198 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KAKDNLLK_01404 2.72e-129 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAKDNLLK_01405 1.27e-66 yitW - - S - - - Iron-sulfur cluster assembly protein
KAKDNLLK_01406 4.87e-203 - - - - - - - -
KAKDNLLK_01407 2.22e-234 - - - - - - - -
KAKDNLLK_01408 2.44e-115 - - - S - - - Protein conserved in bacteria
KAKDNLLK_01411 1.99e-146 - - - K - - - Transcriptional regulator
KAKDNLLK_01412 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KAKDNLLK_01413 5.08e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
KAKDNLLK_01414 4.17e-60 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KAKDNLLK_01415 1.63e-171 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAKDNLLK_01416 6.11e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KAKDNLLK_01417 2.2e-150 - - - J - - - 2'-5' RNA ligase superfamily
KAKDNLLK_01418 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
KAKDNLLK_01419 1.84e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAKDNLLK_01420 3.12e-190 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAKDNLLK_01421 6.32e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KAKDNLLK_01422 9.86e-59 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KAKDNLLK_01423 2.43e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KAKDNLLK_01424 6.89e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KAKDNLLK_01425 1.11e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KAKDNLLK_01426 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KAKDNLLK_01427 9e-72 - - - - - - - -
KAKDNLLK_01428 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KAKDNLLK_01429 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KAKDNLLK_01430 3.26e-275 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAKDNLLK_01431 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAKDNLLK_01432 2.12e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAKDNLLK_01433 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAKDNLLK_01434 1.05e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KAKDNLLK_01435 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KAKDNLLK_01436 2.96e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KAKDNLLK_01437 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KAKDNLLK_01438 1.64e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KAKDNLLK_01439 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KAKDNLLK_01440 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
KAKDNLLK_01441 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
KAKDNLLK_01442 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAKDNLLK_01443 1.92e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KAKDNLLK_01444 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAKDNLLK_01445 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KAKDNLLK_01446 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KAKDNLLK_01447 7.26e-264 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KAKDNLLK_01448 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KAKDNLLK_01449 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAKDNLLK_01450 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KAKDNLLK_01451 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KAKDNLLK_01452 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAKDNLLK_01453 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KAKDNLLK_01454 0.0 - - - E ko:K03294 - ko00000 amino acid
KAKDNLLK_01455 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KAKDNLLK_01456 2.53e-264 - - - L - - - Belongs to the 'phage' integrase family
KAKDNLLK_01457 5.42e-42 - - - - - - - -
KAKDNLLK_01459 4.04e-149 - - - - - - - -
KAKDNLLK_01461 2.72e-07 - - - E - - - Pfam:DUF955
KAKDNLLK_01462 8.65e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
KAKDNLLK_01463 9.7e-35 - - - - - - - -
KAKDNLLK_01465 1.61e-145 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
KAKDNLLK_01470 3.2e-24 - - - S - - - Domain of unknown function (DUF771)
KAKDNLLK_01473 1.84e-67 - - - L - - - DnaD domain protein
KAKDNLLK_01474 5.58e-39 - - - L ko:K07483 - ko00000 transposase activity
KAKDNLLK_01475 5.58e-39 - - - L ko:K07483 - ko00000 transposase activity
KAKDNLLK_01476 1.74e-77 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
KAKDNLLK_01477 6.27e-279 - - - L ko:K07487 - ko00000 Transposase
KAKDNLLK_01479 2.58e-46 - - - - - - - -
KAKDNLLK_01480 4.29e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
KAKDNLLK_01481 2.53e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KAKDNLLK_01482 8.99e-109 - - - - - - - -
KAKDNLLK_01483 8.14e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KAKDNLLK_01484 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KAKDNLLK_01485 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
KAKDNLLK_01486 2.3e-228 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KAKDNLLK_01487 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
KAKDNLLK_01488 1.91e-185 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
KAKDNLLK_01489 4.01e-283 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
KAKDNLLK_01490 1.24e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KAKDNLLK_01491 4.44e-292 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KAKDNLLK_01492 1.66e-213 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
KAKDNLLK_01493 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAKDNLLK_01495 1.57e-157 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
KAKDNLLK_01496 8.27e-194 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KAKDNLLK_01497 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
KAKDNLLK_01498 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
KAKDNLLK_01499 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_01501 1.42e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAKDNLLK_01502 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KAKDNLLK_01503 3.82e-157 - - - S - - - repeat protein
KAKDNLLK_01504 2.83e-159 pgm6 - - G - - - phosphoglycerate mutase
KAKDNLLK_01505 5.32e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KAKDNLLK_01506 3.92e-76 XK27_04120 - - S - - - Putative amino acid metabolism
KAKDNLLK_01507 1.1e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KAKDNLLK_01508 9.75e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAKDNLLK_01509 1.54e-33 - - - - - - - -
KAKDNLLK_01510 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KAKDNLLK_01511 3.3e-43 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KAKDNLLK_01512 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAKDNLLK_01513 3.03e-108 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
KAKDNLLK_01514 1.84e-190 ylmH - - S - - - S4 domain protein
KAKDNLLK_01515 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
KAKDNLLK_01516 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KAKDNLLK_01517 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAKDNLLK_01518 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KAKDNLLK_01519 7.45e-196 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KAKDNLLK_01520 2.52e-261 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAKDNLLK_01521 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAKDNLLK_01522 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAKDNLLK_01523 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KAKDNLLK_01524 5.99e-74 ftsL - - D - - - Cell division protein FtsL
KAKDNLLK_01525 1.54e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KAKDNLLK_01526 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KAKDNLLK_01527 2.32e-75 - - - - - - - -
KAKDNLLK_01528 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
KAKDNLLK_01529 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KAKDNLLK_01530 2.64e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KAKDNLLK_01531 4.72e-205 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
KAKDNLLK_01532 8.94e-250 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KAKDNLLK_01536 2.69e-167 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
KAKDNLLK_01537 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KAKDNLLK_01538 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KAKDNLLK_01539 1.5e-220 ydbI - - K - - - AI-2E family transporter
KAKDNLLK_01540 4.67e-301 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KAKDNLLK_01541 1.76e-146 - - - S - - - Haloacid dehalogenase-like hydrolase
KAKDNLLK_01542 2.61e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAKDNLLK_01543 1.96e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KAKDNLLK_01544 4.4e-217 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KAKDNLLK_01545 1.75e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KAKDNLLK_01546 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KAKDNLLK_01547 1.24e-182 - - - K - - - LysR substrate binding domain
KAKDNLLK_01548 8.18e-70 - - - S - - - branched-chain amino acid
KAKDNLLK_01549 6.56e-184 - - - E - - - AzlC protein
KAKDNLLK_01550 3.73e-264 hpk31 - - T - - - Histidine kinase
KAKDNLLK_01551 9.76e-161 vanR - - K - - - response regulator
KAKDNLLK_01552 7.28e-266 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KAKDNLLK_01553 2.03e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
KAKDNLLK_01554 1.89e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
KAKDNLLK_01555 4.73e-302 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
KAKDNLLK_01556 3.97e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAKDNLLK_01557 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAKDNLLK_01558 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
KAKDNLLK_01559 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KAKDNLLK_01560 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
KAKDNLLK_01561 1.61e-196 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KAKDNLLK_01562 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
KAKDNLLK_01563 3.73e-200 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KAKDNLLK_01564 7.65e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KAKDNLLK_01565 1.78e-209 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
KAKDNLLK_01566 2.47e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
KAKDNLLK_01567 1.69e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
KAKDNLLK_01568 3.73e-287 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KAKDNLLK_01569 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_01570 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KAKDNLLK_01571 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAKDNLLK_01573 9.22e-104 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KAKDNLLK_01574 4.08e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KAKDNLLK_01575 8.05e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KAKDNLLK_01576 1.9e-261 coiA - - S ko:K06198 - ko00000 Competence protein
KAKDNLLK_01577 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KAKDNLLK_01578 2.82e-147 yjbH - - Q - - - Thioredoxin
KAKDNLLK_01579 1.29e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KAKDNLLK_01580 1.52e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAKDNLLK_01581 3.94e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KAKDNLLK_01582 5.39e-64 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
KAKDNLLK_01583 2.49e-278 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KAKDNLLK_01584 1.14e-263 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KAKDNLLK_01585 1.22e-94 - - - M - - - transferase activity, transferring glycosyl groups
KAKDNLLK_01586 1.23e-107 - - - - - - - -
KAKDNLLK_01587 3.41e-38 - - - M - - - biosynthesis protein
KAKDNLLK_01588 7.78e-96 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
KAKDNLLK_01589 1.46e-82 - - - S - - - Glycosyltransferase like family
KAKDNLLK_01590 7.07e-98 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
KAKDNLLK_01591 3.39e-95 - - - - - - - -
KAKDNLLK_01592 2.83e-184 - - - M - - - Glycosyl transferase family 2
KAKDNLLK_01593 2.43e-64 - - - S - - - FRG
KAKDNLLK_01594 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KAKDNLLK_01596 1.38e-44 - - - S - - - Domain of unknown function DUF1829
KAKDNLLK_01597 2.34e-207 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KAKDNLLK_01598 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KAKDNLLK_01599 1.1e-261 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KAKDNLLK_01600 6.42e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KAKDNLLK_01601 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KAKDNLLK_01602 0.0 - - - EGP - - - Major Facilitator
KAKDNLLK_01603 1.5e-128 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KAKDNLLK_01604 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KAKDNLLK_01605 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KAKDNLLK_01606 5.07e-56 - - - - - - - -
KAKDNLLK_01607 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KAKDNLLK_01608 3.34e-46 - - - - - - - -
KAKDNLLK_01611 1.65e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
KAKDNLLK_01615 2.91e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAKDNLLK_01616 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
KAKDNLLK_01617 5.35e-113 - - - T - - - Belongs to the universal stress protein A family
KAKDNLLK_01618 8.15e-227 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KAKDNLLK_01619 6.18e-150 dgk2 - - F - - - deoxynucleoside kinase
KAKDNLLK_01620 8.84e-146 - - - - - - - -
KAKDNLLK_01621 1.98e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
KAKDNLLK_01622 5.7e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KAKDNLLK_01623 1.78e-42 - - - - - - - -
KAKDNLLK_01624 1.22e-150 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
KAKDNLLK_01625 9.17e-59 - - - - - - - -
KAKDNLLK_01628 6.59e-14 - - - M - - - LysM domain
KAKDNLLK_01629 1.17e-68 - - - - - - - -
KAKDNLLK_01630 8.69e-185 - - - S - - - Domain of unknown function DUF1829
KAKDNLLK_01631 5.58e-39 - - - L ko:K07483 - ko00000 transposase activity
KAKDNLLK_01632 6.93e-78 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_01633 6.28e-59 - - - M - - - LPXTG-motif cell wall anchor domain protein
KAKDNLLK_01634 4.71e-221 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KAKDNLLK_01635 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KAKDNLLK_01636 3.53e-315 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KAKDNLLK_01637 2.18e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KAKDNLLK_01638 3.3e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KAKDNLLK_01639 1.32e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAKDNLLK_01640 1.56e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KAKDNLLK_01641 2.3e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KAKDNLLK_01642 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAKDNLLK_01643 8.43e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KAKDNLLK_01644 2.15e-75 - - - - - - - -
KAKDNLLK_01646 5e-245 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KAKDNLLK_01647 4.37e-39 - - - - - - - -
KAKDNLLK_01648 3.86e-235 - - - I - - - Diacylglycerol kinase catalytic
KAKDNLLK_01649 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
KAKDNLLK_01650 5.42e-105 - - - - - - - -
KAKDNLLK_01651 4.81e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KAKDNLLK_01652 4.05e-266 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KAKDNLLK_01653 3.28e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
KAKDNLLK_01654 1.5e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KAKDNLLK_01655 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KAKDNLLK_01656 5.79e-62 yktA - - S - - - Belongs to the UPF0223 family
KAKDNLLK_01657 5.83e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
KAKDNLLK_01658 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KAKDNLLK_01659 2.75e-286 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KAKDNLLK_01660 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
KAKDNLLK_01661 4.59e-127 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
KAKDNLLK_01662 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAKDNLLK_01663 2.58e-253 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KAKDNLLK_01664 2.39e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
KAKDNLLK_01665 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KAKDNLLK_01666 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KAKDNLLK_01667 9.31e-193 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KAKDNLLK_01668 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KAKDNLLK_01669 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAKDNLLK_01670 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KAKDNLLK_01671 3.58e-208 - - - S - - - Tetratricopeptide repeat
KAKDNLLK_01672 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAKDNLLK_01673 2.26e-302 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KAKDNLLK_01674 5.06e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAKDNLLK_01675 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KAKDNLLK_01676 2.25e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
KAKDNLLK_01677 4.93e-20 - - - - - - - -
KAKDNLLK_01678 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KAKDNLLK_01679 9.49e-317 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAKDNLLK_01680 1.96e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KAKDNLLK_01681 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
KAKDNLLK_01682 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KAKDNLLK_01683 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAKDNLLK_01684 4.22e-122 - - - - - - - -
KAKDNLLK_01686 8.42e-163 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAKDNLLK_01687 4.08e-270 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
KAKDNLLK_01688 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KAKDNLLK_01689 2.7e-47 ynzC - - S - - - UPF0291 protein
KAKDNLLK_01690 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
KAKDNLLK_01691 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KAKDNLLK_01692 4.85e-181 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
KAKDNLLK_01693 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
KAKDNLLK_01694 3.27e-230 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAKDNLLK_01695 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KAKDNLLK_01696 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAKDNLLK_01697 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KAKDNLLK_01698 8.54e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KAKDNLLK_01699 7.45e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAKDNLLK_01700 4.1e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KAKDNLLK_01701 2.83e-299 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KAKDNLLK_01702 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KAKDNLLK_01703 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KAKDNLLK_01704 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KAKDNLLK_01705 1.68e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KAKDNLLK_01706 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
KAKDNLLK_01707 1.61e-64 ylxQ - - J - - - ribosomal protein
KAKDNLLK_01708 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAKDNLLK_01709 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAKDNLLK_01710 7.03e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAKDNLLK_01711 3.65e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KAKDNLLK_01712 3.09e-85 - - - - - - - -
KAKDNLLK_01713 1.13e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KAKDNLLK_01714 6.65e-117 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAKDNLLK_01715 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KAKDNLLK_01716 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KAKDNLLK_01717 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KAKDNLLK_01718 2.96e-251 - - - S - - - OPT oligopeptide transporter protein
KAKDNLLK_01719 9.96e-26 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
KAKDNLLK_01720 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KAKDNLLK_01721 1.01e-254 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
KAKDNLLK_01723 1.37e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KAKDNLLK_01725 7.92e-76 - - - - - - - -
KAKDNLLK_01726 1.62e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KAKDNLLK_01727 1.37e-164 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KAKDNLLK_01728 4.8e-72 - - - - - - - -
KAKDNLLK_01729 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAKDNLLK_01730 2.56e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KAKDNLLK_01731 6.79e-217 - - - G - - - Phosphotransferase enzyme family
KAKDNLLK_01732 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KAKDNLLK_01733 4.45e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_01734 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KAKDNLLK_01735 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KAKDNLLK_01736 1.11e-90 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
KAKDNLLK_01737 6.18e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KAKDNLLK_01738 4.19e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KAKDNLLK_01739 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KAKDNLLK_01740 4.19e-120 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KAKDNLLK_01741 2.77e-223 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KAKDNLLK_01742 6.39e-235 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KAKDNLLK_01743 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAKDNLLK_01744 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KAKDNLLK_01745 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KAKDNLLK_01746 2.92e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KAKDNLLK_01747 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KAKDNLLK_01748 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KAKDNLLK_01749 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KAKDNLLK_01750 5.12e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KAKDNLLK_01751 2.93e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KAKDNLLK_01752 3.4e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KAKDNLLK_01753 2.07e-198 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAKDNLLK_01754 9.52e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KAKDNLLK_01755 7.94e-42 - - - S - - - Protein of unknown function (DUF2929)
KAKDNLLK_01756 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KAKDNLLK_01757 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KAKDNLLK_01758 9.26e-216 yitL - - S ko:K00243 - ko00000 S1 domain
KAKDNLLK_01759 3.48e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
KAKDNLLK_01760 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KAKDNLLK_01761 2.37e-178 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KAKDNLLK_01762 1.35e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAKDNLLK_01763 2.39e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KAKDNLLK_01765 9.46e-86 - - - L - - - Belongs to the 'phage' integrase family
KAKDNLLK_01768 1.49e-78 - - - J ko:K10716 - ko00000,ko02000 Ion transport protein
KAKDNLLK_01769 8e-11 - - - - - - - -
KAKDNLLK_01771 3.08e-34 - - - K - - - Helix-turn-helix XRE-family like proteins
KAKDNLLK_01772 4.03e-25 - - - - - - - -
KAKDNLLK_01774 8.28e-67 - - - - - - - -
KAKDNLLK_01778 3.98e-173 - - - L - - - DnaD domain protein
KAKDNLLK_01780 7.4e-90 - - - - - - - -
KAKDNLLK_01781 1.55e-171 - - - - - - - -
KAKDNLLK_01788 3.44e-89 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
KAKDNLLK_01791 3.04e-100 - - - - - - - -
KAKDNLLK_01793 1.69e-08 - - - - - - - -
KAKDNLLK_01796 1.9e-126 - - - L - - - HNH nucleases
KAKDNLLK_01797 5.23e-107 - - - L - - - Phage terminase, small subunit
KAKDNLLK_01799 1.59e-13 - - - - - - - -
KAKDNLLK_01800 0.0 - - - S - - - Phage Terminase
KAKDNLLK_01802 1.11e-249 - - - S - - - Phage portal protein
KAKDNLLK_01803 1.43e-83 - - - S - - - Clp protease
KAKDNLLK_01804 3.62e-177 - - - S - - - Phage capsid family
KAKDNLLK_01805 2.69e-56 - - - S - - - Phage gp6-like head-tail connector protein
KAKDNLLK_01806 6.41e-77 - - - S - - - Phage head-tail joining protein
KAKDNLLK_01807 1.11e-92 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KAKDNLLK_01808 5.26e-88 - - - S - - - Protein of unknown function (DUF806)
KAKDNLLK_01809 3.55e-171 - - - S - - - Phage tail tube protein
KAKDNLLK_01810 6.44e-78 - - - S - - - Phage tail assembly chaperone proteins, TAC
KAKDNLLK_01811 0.0 - - - L - - - Phage tail tape measure protein TP901
KAKDNLLK_01812 4.28e-190 - - - S - - - Phage tail protein
KAKDNLLK_01813 0.0 - - - M - - - Prophage endopeptidase tail
KAKDNLLK_01814 3.12e-49 - - - - - - - -
KAKDNLLK_01816 8e-109 - - - S - - - Domain of unknown function (DUF2479)
KAKDNLLK_01820 5.2e-48 - - - S - - - Bacteriophage holin family
KAKDNLLK_01821 4.49e-72 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
KAKDNLLK_01822 4.46e-254 - - - M - - - hydrolase, family 25
KAKDNLLK_01823 2.87e-42 - - - S - - - Bacteriophage abortive infection AbiH
KAKDNLLK_01826 7.6e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KAKDNLLK_01827 5.13e-244 - - - S - - - Helix-turn-helix domain
KAKDNLLK_01828 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KAKDNLLK_01829 1.04e-69 - - - M - - - Lysin motif
KAKDNLLK_01830 1.55e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KAKDNLLK_01831 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KAKDNLLK_01832 9.51e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KAKDNLLK_01833 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KAKDNLLK_01834 9.5e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
KAKDNLLK_01835 8.18e-286 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KAKDNLLK_01836 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_01837 1.04e-246 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAKDNLLK_01838 2.78e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KAKDNLLK_01839 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
KAKDNLLK_01840 6.38e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
KAKDNLLK_01841 7.94e-220 - - - E - - - lipolytic protein G-D-S-L family
KAKDNLLK_01842 2.01e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
KAKDNLLK_01843 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
KAKDNLLK_01844 2.08e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAKDNLLK_01845 1.5e-182 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAKDNLLK_01846 1.85e-205 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KAKDNLLK_01847 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAKDNLLK_01848 1.42e-214 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KAKDNLLK_01849 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KAKDNLLK_01850 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KAKDNLLK_01851 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KAKDNLLK_01852 4.86e-111 - - - F - - - NUDIX domain
KAKDNLLK_01853 8.59e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KAKDNLLK_01854 1.5e-88 - - - S - - - Belongs to the HesB IscA family
KAKDNLLK_01855 1.11e-66 - - - - - - - -
KAKDNLLK_01857 2.99e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KAKDNLLK_01858 2.71e-81 asp1 - - S - - - Asp23 family, cell envelope-related function
KAKDNLLK_01859 6.23e-35 - - - - - - - -
KAKDNLLK_01860 1.89e-123 - - - - - - - -
KAKDNLLK_01861 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KAKDNLLK_01862 8.32e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
KAKDNLLK_01863 2.81e-297 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
KAKDNLLK_01864 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KAKDNLLK_01865 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
KAKDNLLK_01866 7.67e-63 - - - - - - - -
KAKDNLLK_01867 1.81e-41 - - - - - - - -
KAKDNLLK_01868 5.81e-96 kduD 1.1.1.100, 1.1.1.127 - IQ ko:K00059,ko:K00065 ko00040,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00040,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KAKDNLLK_01869 4.33e-27 - - - K - - - MerR family regulatory protein
KAKDNLLK_01870 1.26e-60 - - - - - - - -
KAKDNLLK_01871 4.91e-99 - - - S - - - Protein of unknown function (DUF805)
KAKDNLLK_01872 1.73e-177 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
KAKDNLLK_01873 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KAKDNLLK_01874 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KAKDNLLK_01875 9.1e-94 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KAKDNLLK_01876 4.13e-228 - - - L - - - Belongs to the 'phage' integrase family
KAKDNLLK_01877 7.11e-64 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
KAKDNLLK_01878 1.37e-51 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
KAKDNLLK_01879 1.29e-59 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
KAKDNLLK_01880 6.55e-78 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
KAKDNLLK_01881 4.16e-14 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
KAKDNLLK_01882 6.55e-09 - - - L - - - Type III restriction enzyme, res subunit
KAKDNLLK_01883 3.37e-128 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
KAKDNLLK_01884 1.88e-27 - - - K - - - Divergent AAA domain protein
KAKDNLLK_01885 1.12e-37 - - - K - - - Putative DNA-binding domain
KAKDNLLK_01886 1.02e-14 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
KAKDNLLK_01888 3.09e-143 - - - L - - - PLD-like domain
KAKDNLLK_01889 0.0 - - - L - - - PLD-like domain
KAKDNLLK_01891 9.03e-229 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
KAKDNLLK_01892 1.21e-227 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KAKDNLLK_01893 2.29e-122 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
KAKDNLLK_01894 3.89e-284 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KAKDNLLK_01895 4.52e-101 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KAKDNLLK_01896 1e-143 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
KAKDNLLK_01897 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KAKDNLLK_01898 2.07e-263 - - - G - - - Transporter, major facilitator family protein
KAKDNLLK_01899 7.08e-142 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
KAKDNLLK_01900 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
KAKDNLLK_01901 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KAKDNLLK_01902 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KAKDNLLK_01903 5.19e-27 - - - - - - - -
KAKDNLLK_01904 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
KAKDNLLK_01905 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
KAKDNLLK_01906 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KAKDNLLK_01907 4.96e-307 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
KAKDNLLK_01908 1.02e-295 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAKDNLLK_01909 4.34e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KAKDNLLK_01910 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KAKDNLLK_01911 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
KAKDNLLK_01912 3.31e-206 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KAKDNLLK_01913 2.39e-146 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
KAKDNLLK_01914 1.43e-51 - - - S - - - Cytochrome B5
KAKDNLLK_01915 1.7e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KAKDNLLK_01916 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
KAKDNLLK_01917 1.54e-191 - - - O - - - Band 7 protein
KAKDNLLK_01918 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
KAKDNLLK_01919 2.9e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
KAKDNLLK_01920 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
KAKDNLLK_01921 4.38e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
KAKDNLLK_01922 1.19e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KAKDNLLK_01923 5.79e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KAKDNLLK_01924 2.43e-241 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
KAKDNLLK_01925 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KAKDNLLK_01926 5.52e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
KAKDNLLK_01927 1.8e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KAKDNLLK_01928 1.67e-273 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KAKDNLLK_01929 1.21e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KAKDNLLK_01930 3.63e-220 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
KAKDNLLK_01931 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KAKDNLLK_01932 6.4e-113 ypmB - - S - - - Protein conserved in bacteria
KAKDNLLK_01933 1.18e-159 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
KAKDNLLK_01934 2.42e-208 - - - EG - - - EamA-like transporter family
KAKDNLLK_01935 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
KAKDNLLK_01936 1.21e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KAKDNLLK_01937 5.84e-131 ypsA - - S - - - Belongs to the UPF0398 family
KAKDNLLK_01938 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KAKDNLLK_01939 6.11e-111 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
KAKDNLLK_01940 2.52e-284 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KAKDNLLK_01941 1.09e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
KAKDNLLK_01942 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
KAKDNLLK_01943 8.85e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAKDNLLK_01944 2.9e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KAKDNLLK_01945 3.19e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
KAKDNLLK_01946 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KAKDNLLK_01947 0.0 FbpA - - K - - - Fibronectin-binding protein
KAKDNLLK_01948 2.95e-207 - - - S - - - EDD domain protein, DegV family
KAKDNLLK_01949 1.58e-125 - - - - - - - -
KAKDNLLK_01950 9.78e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KAKDNLLK_01951 7.28e-101 - - - L ko:K07491 - ko00000 Transposase IS200 like
KAKDNLLK_01952 1.09e-292 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KAKDNLLK_01953 3.59e-203 gspA - - M - - - family 8
KAKDNLLK_01954 2e-204 - - - S - - - Alpha beta hydrolase
KAKDNLLK_01955 9.11e-123 - - - K - - - Acetyltransferase (GNAT) domain
KAKDNLLK_01956 1.28e-309 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KAKDNLLK_01957 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KAKDNLLK_01958 0.0 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
KAKDNLLK_01960 9.96e-218 yvgN - - C - - - Aldo keto reductase
KAKDNLLK_01961 1.4e-206 rlrB - - K - - - LysR substrate binding domain protein
KAKDNLLK_01962 1.38e-107 - - - C - - - Flavodoxin
KAKDNLLK_01963 1.15e-18 - - - S - - - Cupin domain
KAKDNLLK_01964 2.72e-97 - - - S - - - UPF0756 membrane protein
KAKDNLLK_01965 6.11e-311 - - - U - - - Belongs to the major facilitator superfamily
KAKDNLLK_01966 9.74e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
KAKDNLLK_01967 9.18e-317 yhdP - - S - - - Transporter associated domain
KAKDNLLK_01968 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
KAKDNLLK_01969 6.07e-185 - - - S - - - DUF218 domain
KAKDNLLK_01970 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KAKDNLLK_01971 2.52e-76 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAKDNLLK_01972 5.16e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAKDNLLK_01973 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
KAKDNLLK_01974 1.18e-157 - - - S - - - SNARE associated Golgi protein
KAKDNLLK_01975 7.69e-293 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KAKDNLLK_01976 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KAKDNLLK_01978 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
KAKDNLLK_01979 1.99e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
KAKDNLLK_01980 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAKDNLLK_01981 5.85e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
KAKDNLLK_01982 9.59e-96 - - - S - - - Protein of unknown function (DUF3290)
KAKDNLLK_01983 4.17e-149 - - - S - - - Protein of unknown function (DUF421)
KAKDNLLK_01984 2.27e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KAKDNLLK_01985 6.9e-27 - - - - - - - -
KAKDNLLK_01986 1.61e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
KAKDNLLK_01987 5.84e-194 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KAKDNLLK_01988 9.63e-65 yrvD - - S - - - Pfam:DUF1049
KAKDNLLK_01993 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KAKDNLLK_01995 2.06e-14 - - - S - - - Phage derived protein Gp49-like (DUF891)
KAKDNLLK_01996 2.6e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
KAKDNLLK_01997 2.06e-208 - - - I - - - alpha/beta hydrolase fold
KAKDNLLK_01998 2.5e-147 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KAKDNLLK_01999 4.5e-73 - - - - - - - -
KAKDNLLK_02000 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KAKDNLLK_02001 3.12e-227 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAKDNLLK_02002 4.82e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KAKDNLLK_02003 1.88e-292 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KAKDNLLK_02004 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAKDNLLK_02005 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KAKDNLLK_02006 1.38e-37 - - - - - - - -
KAKDNLLK_02007 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
KAKDNLLK_02008 2.59e-129 - - - S - - - Pfam:DUF3816
KAKDNLLK_02009 9.48e-183 - - - G - - - MucBP domain
KAKDNLLK_02010 1.73e-149 - - - - - - - -
KAKDNLLK_02011 9.08e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_02012 4.16e-85 - - - K - - - Transcriptional regulator, GntR family
KAKDNLLK_02013 0.0 - - - S - - - Peptidase, M23
KAKDNLLK_02014 0.0 - - - M - - - NlpC/P60 family
KAKDNLLK_02015 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAKDNLLK_02016 9.71e-301 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KAKDNLLK_02017 9.19e-233 yueF - - S - - - AI-2E family transporter
KAKDNLLK_02018 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
KAKDNLLK_02019 5.58e-39 - - - L ko:K07483 - ko00000 transposase activity
KAKDNLLK_02020 1.32e-79 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
KAKDNLLK_02021 1.81e-90 - - - - - - - -
KAKDNLLK_02022 1.01e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAKDNLLK_02023 3.74e-120 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KAKDNLLK_02024 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
KAKDNLLK_02025 1.65e-284 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KAKDNLLK_02026 8.19e-134 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
KAKDNLLK_02027 3.22e-268 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
KAKDNLLK_02028 1.88e-60 - - - - - - - -
KAKDNLLK_02029 1.49e-54 - - - - - - - -
KAKDNLLK_02031 3.88e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KAKDNLLK_02032 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KAKDNLLK_02033 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KAKDNLLK_02034 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KAKDNLLK_02035 1.59e-78 yheA - - S - - - Belongs to the UPF0342 family
KAKDNLLK_02036 4.22e-288 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
KAKDNLLK_02037 0.0 yhaN - - L - - - AAA domain
KAKDNLLK_02038 1.22e-177 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KAKDNLLK_02040 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
KAKDNLLK_02041 1.9e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KAKDNLLK_02042 2.32e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KAKDNLLK_02043 1.85e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KAKDNLLK_02044 0.0 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
KAKDNLLK_02045 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
KAKDNLLK_02046 3.84e-234 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
KAKDNLLK_02047 1.04e-214 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KAKDNLLK_02048 2.27e-75 - - - S - - - Small secreted protein
KAKDNLLK_02049 2.95e-75 ytpP - - CO - - - Thioredoxin
KAKDNLLK_02050 6.65e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KAKDNLLK_02051 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KAKDNLLK_02052 9.2e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KAKDNLLK_02053 3.4e-152 - - - S - - - Protein of unknown function (DUF1275)
KAKDNLLK_02054 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAKDNLLK_02055 1.58e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KAKDNLLK_02056 2.62e-132 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KAKDNLLK_02057 1.63e-104 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAKDNLLK_02058 1.99e-300 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
KAKDNLLK_02059 5.8e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KAKDNLLK_02060 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAKDNLLK_02061 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KAKDNLLK_02062 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAKDNLLK_02063 1.34e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
KAKDNLLK_02064 7.72e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
KAKDNLLK_02065 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
KAKDNLLK_02066 9.89e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAKDNLLK_02067 4.91e-144 yqeK - - H - - - Hydrolase, HD family
KAKDNLLK_02068 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KAKDNLLK_02069 3.16e-179 yqeM - - Q - - - Methyltransferase
KAKDNLLK_02070 1.27e-269 ylbM - - S - - - Belongs to the UPF0348 family
KAKDNLLK_02071 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KAKDNLLK_02072 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KAKDNLLK_02073 5.62e-155 csrR - - K - - - response regulator
KAKDNLLK_02074 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KAKDNLLK_02075 0.0 potE - - E - - - Amino Acid
KAKDNLLK_02076 8.72e-297 - - - V - - - MatE
KAKDNLLK_02077 6.2e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KAKDNLLK_02078 5.52e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KAKDNLLK_02079 8.53e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KAKDNLLK_02080 2.71e-186 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAKDNLLK_02081 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KAKDNLLK_02082 4.77e-77 yodB - - K - - - Transcriptional regulator, HxlR family
KAKDNLLK_02083 1.81e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAKDNLLK_02084 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KAKDNLLK_02085 2.07e-149 - - - M - - - PFAM NLP P60 protein
KAKDNLLK_02086 4.85e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KAKDNLLK_02087 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KAKDNLLK_02088 5.43e-91 yneR - - S - - - Belongs to the HesB IscA family
KAKDNLLK_02089 0.0 - - - S - - - membrane
KAKDNLLK_02090 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KAKDNLLK_02091 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KAKDNLLK_02092 2.68e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAKDNLLK_02093 2.39e-147 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
KAKDNLLK_02094 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
KAKDNLLK_02095 1.77e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KAKDNLLK_02096 5.09e-93 yqhL - - P - - - Rhodanese-like protein
KAKDNLLK_02097 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
KAKDNLLK_02098 7.13e-227 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAKDNLLK_02099 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KAKDNLLK_02100 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAKDNLLK_02101 9.05e-278 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KAKDNLLK_02102 1.28e-18 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)