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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NCIFGHOL_00001	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NCIFGHOL_00002	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
NCIFGHOL_00003	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NCIFGHOL_00004	3.72e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NCIFGHOL_00005	4.85e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NCIFGHOL_00006	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NCIFGHOL_00007	3.56e-234	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCIFGHOL_00008	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NCIFGHOL_00009	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NCIFGHOL_00010	2.97e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NCIFGHOL_00011	8.54e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NCIFGHOL_00012	3.03e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NCIFGHOL_00013	4.1e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NCIFGHOL_00014	4.02e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NCIFGHOL_00015	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NCIFGHOL_00016	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCIFGHOL_00017	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NCIFGHOL_00018	2.9e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NCIFGHOL_00019	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NCIFGHOL_00020	2.29e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
NCIFGHOL_00021	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NCIFGHOL_00022	5.63e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NCIFGHOL_00023	1.59e-211	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NCIFGHOL_00024	9.36e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NCIFGHOL_00025	1.04e-83	-	-	-	-	-	-	-	-
NCIFGHOL_00026	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NCIFGHOL_00027	3.69e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NCIFGHOL_00028	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NCIFGHOL_00029	1.81e-272	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NCIFGHOL_00030	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NCIFGHOL_00031	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NCIFGHOL_00032	1.38e-252	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NCIFGHOL_00033	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NCIFGHOL_00035	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NCIFGHOL_00036	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
NCIFGHOL_00037	1.58e-125	-	-	-	-	-	-	-	-
NCIFGHOL_00038	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00039	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NCIFGHOL_00040	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NCIFGHOL_00041	6.34e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NCIFGHOL_00042	8.8e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NCIFGHOL_00043	2.26e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NCIFGHOL_00044	3.78e-271	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NCIFGHOL_00045	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00046	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NCIFGHOL_00047	5.42e-110	-	-	-	-	-	-	-	-
NCIFGHOL_00048	2.53e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NCIFGHOL_00049	7.12e-69	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
NCIFGHOL_00050	2.58e-46	-	-	-	-	-	-	-	-
NCIFGHOL_00051	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NCIFGHOL_00052	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
NCIFGHOL_00053	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NCIFGHOL_00054	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NCIFGHOL_00055	5.12e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NCIFGHOL_00056	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NCIFGHOL_00057	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NCIFGHOL_00058	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NCIFGHOL_00059	1.18e-254	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NCIFGHOL_00060	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NCIFGHOL_00061	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NCIFGHOL_00062	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCIFGHOL_00063	1.58e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NCIFGHOL_00064	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NCIFGHOL_00065	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NCIFGHOL_00066	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NCIFGHOL_00067	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NCIFGHOL_00068	1.35e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NCIFGHOL_00069	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NCIFGHOL_00070	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NCIFGHOL_00071	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NCIFGHOL_00072	1.22e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NCIFGHOL_00073	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NCIFGHOL_00074	3.51e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NCIFGHOL_00075	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NCIFGHOL_00076	1.55e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NCIFGHOL_00077	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NCIFGHOL_00078	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NCIFGHOL_00079	8.66e-70	-	-	-	-	-	-	-	-
NCIFGHOL_00080	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NCIFGHOL_00081	4.54e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NCIFGHOL_00082	6.89e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NCIFGHOL_00083	1.29e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NCIFGHOL_00084	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCIFGHOL_00085	6.84e-281	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCIFGHOL_00086	6.29e-190	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NCIFGHOL_00087	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NCIFGHOL_00088	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NCIFGHOL_00089	1.17e-145	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
NCIFGHOL_00090	5.02e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NCIFGHOL_00091	2.7e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NCIFGHOL_00092	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NCIFGHOL_00093	5.08e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NCIFGHOL_00094	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NCIFGHOL_00095	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_00098	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00099	6.32e-227	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NCIFGHOL_00100	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NCIFGHOL_00102	9.06e-125	-	-	-	S	-	-	-	reductase
NCIFGHOL_00103	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
NCIFGHOL_00104	9.8e-199	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NCIFGHOL_00105	5.08e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
NCIFGHOL_00106	7.14e-188	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NCIFGHOL_00107	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NCIFGHOL_00108	1.12e-197	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCIFGHOL_00109	1.98e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NCIFGHOL_00110	5.58e-272	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NCIFGHOL_00112	3.4e-68	-	-	-	-	-	-	-	-
NCIFGHOL_00113	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NCIFGHOL_00116	1.38e-248	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NCIFGHOL_00117	3.85e-160	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NCIFGHOL_00120	2.4e-303	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NCIFGHOL_00122	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
NCIFGHOL_00123	9.3e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCIFGHOL_00124	2.04e-275	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NCIFGHOL_00125	4.15e-42	-	-	-	-	-	-	-	-
NCIFGHOL_00126	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NCIFGHOL_00127	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00128	5.86e-63	-	-	-	V	-	-	-	Pfam:Methyltransf_26
NCIFGHOL_00129	2.18e-188	-	-	-	V	-	-	-	Pfam:Methyltransf_26
NCIFGHOL_00132	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NCIFGHOL_00133	4.56e-211	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NCIFGHOL_00134	2.13e-136	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NCIFGHOL_00135	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NCIFGHOL_00136	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NCIFGHOL_00137	1.83e-106	-	-	-	F	-	-	-	NUDIX domain
NCIFGHOL_00138	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NCIFGHOL_00139	1.5e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NCIFGHOL_00140	3.19e-66	-	-	-	-	-	-	-	-
NCIFGHOL_00142	2.19e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NCIFGHOL_00143	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NCIFGHOL_00144	6.23e-35	-	-	-	-	-	-	-	-
NCIFGHOL_00145	1.89e-123	-	-	-	-	-	-	-	-
NCIFGHOL_00146	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NCIFGHOL_00147	1.14e-232	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
NCIFGHOL_00148	5.67e-297	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NCIFGHOL_00149	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NCIFGHOL_00150	1.39e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NCIFGHOL_00152	1.81e-06	-	2.7.13.3, 2.7.7.7, 5.4.99.21	-	D	ko:K02343,ko:K03407,ko:K06182,ko:K08372,ko:K12065,ko:K16291	ko00230,ko00240,ko01100,ko02020,ko02030,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map02030,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko02022,ko02035,ko02044,ko03009,ko03032,ko03400	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NCIFGHOL_00153	1.15e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NCIFGHOL_00154	8.66e-89	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NCIFGHOL_00155	3.85e-242	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NCIFGHOL_00156	0.0	arcT	-	-	E	-	-	-	Dipeptidase
NCIFGHOL_00157	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NCIFGHOL_00158	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
NCIFGHOL_00159	6.8e-179	-	-	-	V	-	-	-	Beta-lactamase enzyme family
NCIFGHOL_00160	3.49e-288	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NCIFGHOL_00161	2.18e-96	-	-	-	-	-	-	-	-
NCIFGHOL_00162	1.04e-150	-	-	-	L	ko:K07487	-	ko00000	Transposase
NCIFGHOL_00163	4.46e-93	-	-	-	L	ko:K07487	-	ko00000	Transposase
NCIFGHOL_00164	5.84e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NCIFGHOL_00165	6.92e-31	-	-	-	-	-	-	-	-
NCIFGHOL_00166	3.35e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NCIFGHOL_00167	1.25e-164	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCIFGHOL_00169	4.57e-06	-	-	-	-	-	-	-	-
NCIFGHOL_00170	1e-88	-	-	-	-	-	-	-	-
NCIFGHOL_00178	1.53e-06	-	-	-	S	-	-	-	Helix-turn-helix domain
NCIFGHOL_00179	4.22e-51	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
NCIFGHOL_00180	1.45e-44	-	-	-	-	-	-	-	-
NCIFGHOL_00181	2.16e-20	-	-	-	-	-	-	-	-
NCIFGHOL_00182	1.13e-06	-	-	-	K	-	-	-	transcriptional regulator, XRE family
NCIFGHOL_00183	1.3e-171	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_00184	1.26e-121	-	-	-	-	-	-	-	-
NCIFGHOL_00185	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NCIFGHOL_00186	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NCIFGHOL_00187	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NCIFGHOL_00188	9.73e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NCIFGHOL_00189	9.49e-317	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NCIFGHOL_00190	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NCIFGHOL_00191	4.93e-20	-	-	-	-	-	-	-	-
NCIFGHOL_00192	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NCIFGHOL_00193	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NCIFGHOL_00194	5.06e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NCIFGHOL_00195	1.59e-302	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NCIFGHOL_00196	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NCIFGHOL_00197	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
NCIFGHOL_00198	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_00199	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NCIFGHOL_00200	8.06e-236	-	-	-	-	-	-	-	-
NCIFGHOL_00201	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCIFGHOL_00202	2.47e-311	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NCIFGHOL_00203	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NCIFGHOL_00204	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NCIFGHOL_00205	9.28e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NCIFGHOL_00206	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NCIFGHOL_00207	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCIFGHOL_00208	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCIFGHOL_00209	7.76e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCIFGHOL_00210	7.43e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NCIFGHOL_00211	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NCIFGHOL_00212	2.04e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NCIFGHOL_00213	7.36e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NCIFGHOL_00214	3.5e-127	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NCIFGHOL_00215	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NCIFGHOL_00216	3.59e-232	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NCIFGHOL_00217	1.48e-29	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NCIFGHOL_00218	1.1e-166	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
NCIFGHOL_00219	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NCIFGHOL_00220	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NCIFGHOL_00221	1.2e-220	ydbI	-	-	K	-	-	-	AI-2E family transporter
NCIFGHOL_00222	1.54e-293	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NCIFGHOL_00223	3.73e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCIFGHOL_00224	4.32e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NCIFGHOL_00225	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NCIFGHOL_00226	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NCIFGHOL_00227	7.94e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NCIFGHOL_00228	2.04e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NCIFGHOL_00229	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NCIFGHOL_00230	8.01e-179	-	-	-	K	-	-	-	LysR substrate binding domain
NCIFGHOL_00231	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
NCIFGHOL_00232	9.98e-195	-	-	-	E	-	-	-	AzlC protein
NCIFGHOL_00233	2.16e-263	hpk31	-	-	T	-	-	-	Histidine kinase
NCIFGHOL_00234	9.76e-161	vanR	-	-	K	-	-	-	response regulator
NCIFGHOL_00235	8.49e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NCIFGHOL_00236	2.03e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
NCIFGHOL_00237	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NCIFGHOL_00238	2.24e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NCIFGHOL_00239	1.62e-298	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NCIFGHOL_00240	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NCIFGHOL_00241	2.99e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NCIFGHOL_00242	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NCIFGHOL_00243	1.41e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NCIFGHOL_00244	1.32e-195	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NCIFGHOL_00245	4.82e-179	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NCIFGHOL_00246	1.97e-195	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NCIFGHOL_00247	1.42e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NCIFGHOL_00248	1.2e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NCIFGHOL_00249	3.5e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NCIFGHOL_00250	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
NCIFGHOL_00251	5.9e-284	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NCIFGHOL_00252	3.28e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_00253	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NCIFGHOL_00254	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NCIFGHOL_00255	3.52e-161	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NCIFGHOL_00256	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NCIFGHOL_00257	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NCIFGHOL_00258	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NCIFGHOL_00259	1.99e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NCIFGHOL_00260	8.38e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
NCIFGHOL_00262	2.62e-109	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NCIFGHOL_00263	9.32e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NCIFGHOL_00264	6.43e-203	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NCIFGHOL_00265	2.17e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NCIFGHOL_00266	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NCIFGHOL_00267	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NCIFGHOL_00268	6.9e-77	-	-	-	-	-	-	-	-
NCIFGHOL_00269	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NCIFGHOL_00270	7.33e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NCIFGHOL_00271	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NCIFGHOL_00272	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NCIFGHOL_00273	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NCIFGHOL_00274	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NCIFGHOL_00275	3.99e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NCIFGHOL_00276	7.99e-191	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NCIFGHOL_00277	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NCIFGHOL_00278	3.1e-287	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NCIFGHOL_00279	1.57e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NCIFGHOL_00280	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NCIFGHOL_00281	1.51e-189	ylmH	-	-	S	-	-	-	S4 domain protein
NCIFGHOL_00282	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NCIFGHOL_00283	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NCIFGHOL_00284	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NCIFGHOL_00285	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NCIFGHOL_00286	2.98e-31	-	-	-	-	-	-	-	-
NCIFGHOL_00287	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NCIFGHOL_00288	1.28e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NCIFGHOL_00289	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NCIFGHOL_00290	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NCIFGHOL_00291	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NCIFGHOL_00292	3.82e-157	-	-	-	S	-	-	-	repeat protein
NCIFGHOL_00293	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NCIFGHOL_00294	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCIFGHOL_00295	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NCIFGHOL_00296	1.29e-218	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NCIFGHOL_00297	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NCIFGHOL_00298	9.35e-311	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NCIFGHOL_00299	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NCIFGHOL_00300	3.17e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NCIFGHOL_00301	5.62e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCIFGHOL_00302	4.46e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NCIFGHOL_00303	2.93e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NCIFGHOL_00304	1.05e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NCIFGHOL_00305	2.42e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NCIFGHOL_00306	2.15e-75	-	-	-	-	-	-	-	-
NCIFGHOL_00308	2.58e-239	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NCIFGHOL_00309	2.44e-36	-	-	-	-	-	-	-	-
NCIFGHOL_00310	7.47e-233	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
NCIFGHOL_00311	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NCIFGHOL_00312	2.21e-104	-	-	-	-	-	-	-	-
NCIFGHOL_00313	4.81e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NCIFGHOL_00314	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NCIFGHOL_00315	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NCIFGHOL_00316	3.68e-312	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NCIFGHOL_00317	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NCIFGHOL_00318	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NCIFGHOL_00319	8.28e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NCIFGHOL_00320	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NCIFGHOL_00321	2.26e-285	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NCIFGHOL_00322	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NCIFGHOL_00323	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NCIFGHOL_00324	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NCIFGHOL_00325	2.58e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NCIFGHOL_00326	1.44e-139	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NCIFGHOL_00327	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NCIFGHOL_00328	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NCIFGHOL_00329	6.49e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NCIFGHOL_00330	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NCIFGHOL_00331	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NCIFGHOL_00332	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCIFGHOL_00333	1.46e-44	-	-	-	S	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NCIFGHOL_00334	1.99e-58	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NCIFGHOL_00335	3.68e-48	-	2.4.1.348	GT4	M	ko:K06338,ko:K12995	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
NCIFGHOL_00336	2.12e-134	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NCIFGHOL_00337	3.33e-207	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NCIFGHOL_00338	2.66e-138	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NCIFGHOL_00339	7.77e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NCIFGHOL_00340	1.07e-199	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCIFGHOL_00342	3.11e-107	-	-	-	S	-	-	-	SIR2-like domain
NCIFGHOL_00343	2.98e-242	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
NCIFGHOL_00344	4.62e-24	-	-	-	-	-	-	-	-
NCIFGHOL_00345	1.63e-06	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NCIFGHOL_00346	1.39e-70	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NAD(P)H-binding
NCIFGHOL_00348	4.46e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
NCIFGHOL_00349	8.27e-79	-	-	-	-	-	-	-	-
NCIFGHOL_00351	8.03e-92	-	-	-	O	-	-	-	Preprotein translocase subunit SecB
NCIFGHOL_00352	7.62e-219	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NCIFGHOL_00353	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NCIFGHOL_00355	2.21e-68	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
NCIFGHOL_00357	0.0	snf	-	-	KL	-	-	-	domain protein
NCIFGHOL_00358	3.16e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NCIFGHOL_00359	3.2e-227	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NCIFGHOL_00360	1.85e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NCIFGHOL_00361	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NCIFGHOL_00362	8.27e-140	-	-	-	C	-	-	-	Luciferase-like monooxygenase
NCIFGHOL_00363	2.31e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NCIFGHOL_00364	1.61e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCIFGHOL_00365	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NCIFGHOL_00366	8.93e-291	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NCIFGHOL_00367	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCIFGHOL_00368	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NCIFGHOL_00369	1.38e-37	-	-	-	-	-	-	-	-
NCIFGHOL_00370	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NCIFGHOL_00371	6.36e-130	-	-	-	S	-	-	-	Pfam:DUF3816
NCIFGHOL_00372	2.72e-182	-	-	-	G	-	-	-	MucBP domain
NCIFGHOL_00373	7.22e-142	-	-	-	-	-	-	-	-
NCIFGHOL_00374	1.15e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_00375	2.93e-85	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NCIFGHOL_00376	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00377	2.54e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NCIFGHOL_00378	1.1e-177	-	-	-	IQ	-	-	-	KR domain
NCIFGHOL_00379	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NCIFGHOL_00380	5.91e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NCIFGHOL_00381	2.21e-165	-	-	-	S	-	-	-	Double zinc ribbon
NCIFGHOL_00382	4.42e-243	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NCIFGHOL_00383	1.12e-170	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NCIFGHOL_00384	3.65e-185	-	-	-	-	-	-	-	-
NCIFGHOL_00387	1.93e-162	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NCIFGHOL_00389	6.13e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NCIFGHOL_00390	8.27e-146	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NCIFGHOL_00391	3.85e-151	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NCIFGHOL_00392	0.0	yagE	-	-	E	-	-	-	amino acid
NCIFGHOL_00393	2.93e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NCIFGHOL_00394	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NCIFGHOL_00395	5.01e-225	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NCIFGHOL_00396	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NCIFGHOL_00397	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NCIFGHOL_00398	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NCIFGHOL_00399	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NCIFGHOL_00400	5.12e-268	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NCIFGHOL_00401	1.24e-296	-	-	-	-	-	-	-	-
NCIFGHOL_00402	1.35e-235	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NCIFGHOL_00403	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NCIFGHOL_00404	1.46e-96	-	-	-	F	-	-	-	Nudix hydrolase
NCIFGHOL_00405	5.82e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NCIFGHOL_00406	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NCIFGHOL_00407	4.77e-36	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NCIFGHOL_00408	3.42e-195	-	-	-	-	-	-	-	-
NCIFGHOL_00409	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
NCIFGHOL_00410	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
NCIFGHOL_00411	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NCIFGHOL_00412	3.41e-232	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCIFGHOL_00413	6.47e-10	-	-	-	S	-	-	-	CsbD-like
NCIFGHOL_00414	1.98e-42	-	-	-	S	-	-	-	Transglycosylase associated protein
NCIFGHOL_00415	9.53e-15	-	-	-	-	-	-	-	-
NCIFGHOL_00416	3.5e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NCIFGHOL_00417	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NCIFGHOL_00418	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NCIFGHOL_00419	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NCIFGHOL_00420	1.26e-44	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NCIFGHOL_00421	2.15e-203	-	-	-	EG	-	-	-	EamA-like transporter family
NCIFGHOL_00422	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NCIFGHOL_00423	6.98e-302	isp	-	-	L	-	-	-	Transposase
NCIFGHOL_00424	3.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NCIFGHOL_00425	7.02e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
NCIFGHOL_00427	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NCIFGHOL_00428	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NCIFGHOL_00429	2.1e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NCIFGHOL_00430	3.3e-203	-	-	-	J	-	-	-	Methyltransferase
NCIFGHOL_00431	7.8e-149	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NCIFGHOL_00432	1.27e-110	-	-	-	-	-	-	-	-
NCIFGHOL_00433	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NCIFGHOL_00434	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NCIFGHOL_00435	1.6e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NCIFGHOL_00436	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NCIFGHOL_00437	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NCIFGHOL_00438	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NCIFGHOL_00439	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NCIFGHOL_00440	4.31e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NCIFGHOL_00441	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
NCIFGHOL_00442	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NCIFGHOL_00443	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NCIFGHOL_00444	3.29e-146	-	-	-	S	-	-	-	(CBS) domain
NCIFGHOL_00445	5.9e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NCIFGHOL_00446	7.57e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
NCIFGHOL_00447	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NCIFGHOL_00448	3.74e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NCIFGHOL_00449	6.26e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NCIFGHOL_00450	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NCIFGHOL_00451	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NCIFGHOL_00452	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NCIFGHOL_00453	8.69e-298	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NCIFGHOL_00454	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NCIFGHOL_00455	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NCIFGHOL_00456	6.87e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NCIFGHOL_00457	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NCIFGHOL_00458	8.32e-80	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NCIFGHOL_00459	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NCIFGHOL_00460	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NCIFGHOL_00461	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NCIFGHOL_00462	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NCIFGHOL_00463	5.7e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCIFGHOL_00464	1.06e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NCIFGHOL_00465	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NCIFGHOL_00466	1.43e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCIFGHOL_00467	9.7e-190	-	-	-	G	-	-	-	Right handed beta helix region
NCIFGHOL_00468	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NCIFGHOL_00469	6.09e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NCIFGHOL_00470	2.76e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NCIFGHOL_00471	2.36e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCIFGHOL_00472	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NCIFGHOL_00473	6.72e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCIFGHOL_00474	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NCIFGHOL_00475	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NCIFGHOL_00476	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NCIFGHOL_00477	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NCIFGHOL_00478	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NCIFGHOL_00479	1.89e-189	yidA	-	-	S	-	-	-	hydrolase
NCIFGHOL_00480	1.6e-100	-	-	-	-	-	-	-	-
NCIFGHOL_00481	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCIFGHOL_00482	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NCIFGHOL_00483	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NCIFGHOL_00484	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NCIFGHOL_00485	2.31e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NCIFGHOL_00486	9.58e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NCIFGHOL_00487	1.35e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NCIFGHOL_00488	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NCIFGHOL_00489	1.98e-228	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NCIFGHOL_00490	1.59e-156	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NCIFGHOL_00491	5.5e-138	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
NCIFGHOL_00492	8.74e-18	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
NCIFGHOL_00493	0.0	-	-	-	L	-	-	-	Transposase
NCIFGHOL_00495	1.77e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NCIFGHOL_00496	2.69e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NCIFGHOL_00497	1.98e-83	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
NCIFGHOL_00498	2.08e-145	-	-	-	S	-	-	-	Membrane
NCIFGHOL_00499	3.14e-195	-	-	-	-	-	-	-	-
NCIFGHOL_00500	2.24e-72	-	-	-	M	-	-	-	Glycosyl transferase
NCIFGHOL_00501	1.87e-224	-	-	-	M	-	-	-	Glycosyl transferase
NCIFGHOL_00502	8.68e-278	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
NCIFGHOL_00503	7.72e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NCIFGHOL_00504	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NCIFGHOL_00505	2.26e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NCIFGHOL_00506	3.97e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
NCIFGHOL_00507	1.54e-113	-	-	-	Q	-	-	-	Methyltransferase
NCIFGHOL_00508	6.6e-294	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NCIFGHOL_00509	4.65e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NCIFGHOL_00510	7.92e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NCIFGHOL_00511	1.83e-124	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NCIFGHOL_00512	4.52e-304	-	-	-	G	ko:K03832	-	ko00000,ko02000	Belongs to the glycosyl hydrolase family 6
NCIFGHOL_00513	1.18e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NCIFGHOL_00514	3.04e-173	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NCIFGHOL_00515	1.97e-69	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NCIFGHOL_00516	5.91e-105	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NCIFGHOL_00517	1.2e-76	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NCIFGHOL_00518	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00519	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NCIFGHOL_00520	6.02e-214	-	-	-	C	-	-	-	Aldo keto reductase
NCIFGHOL_00521	4.14e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NCIFGHOL_00522	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NCIFGHOL_00523	6.98e-266	-	-	-	P	-	-	-	Voltage gated chloride channel
NCIFGHOL_00524	4.21e-285	sptS	-	-	T	-	-	-	Histidine kinase
NCIFGHOL_00525	7.43e-152	dltr	-	-	K	-	-	-	response regulator
NCIFGHOL_00526	5.05e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
NCIFGHOL_00527	4.9e-77	-	-	-	-	-	-	-	-
NCIFGHOL_00528	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NCIFGHOL_00529	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NCIFGHOL_00530	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NCIFGHOL_00531	3e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NCIFGHOL_00532	4.44e-223	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NCIFGHOL_00533	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NCIFGHOL_00534	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NCIFGHOL_00535	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCIFGHOL_00536	5.56e-136	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NCIFGHOL_00538	2.78e-53	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_00539	4.05e-165	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NCIFGHOL_00540	1.75e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCIFGHOL_00541	5.1e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NCIFGHOL_00542	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NCIFGHOL_00543	2.01e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NCIFGHOL_00544	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NCIFGHOL_00545	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NCIFGHOL_00546	1.05e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NCIFGHOL_00547	1.88e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCIFGHOL_00548	1.65e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NCIFGHOL_00549	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_00550	8.18e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NCIFGHOL_00551	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCIFGHOL_00552	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NCIFGHOL_00553	9.51e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NCIFGHOL_00554	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NCIFGHOL_00555	4.43e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NCIFGHOL_00556	1.04e-69	-	-	-	M	-	-	-	Lysin motif
NCIFGHOL_00557	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NCIFGHOL_00558	7.08e-251	-	-	-	S	-	-	-	Helix-turn-helix domain
NCIFGHOL_00559	1.65e-127	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NCIFGHOL_00560	1.49e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NCIFGHOL_00561	7.8e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NCIFGHOL_00562	1.13e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NCIFGHOL_00563	3.02e-85	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NCIFGHOL_00564	1.16e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NCIFGHOL_00565	4.59e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NCIFGHOL_00566	6.39e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NCIFGHOL_00567	1.94e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NCIFGHOL_00568	1.79e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NCIFGHOL_00569	2.05e-66	-	-	-	-	-	-	-	-
NCIFGHOL_00570	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
NCIFGHOL_00571	1.7e-157	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NCIFGHOL_00572	1.28e-94	-	-	-	-	-	-	-	-
NCIFGHOL_00573	9.24e-220	-	-	-	-	-	-	-	-
NCIFGHOL_00574	1.16e-223	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NCIFGHOL_00575	4.75e-171	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NCIFGHOL_00576	1.25e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCIFGHOL_00577	1.21e-95	-	-	-	S	-	-	-	Flavodoxin
NCIFGHOL_00578	5.19e-81	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
NCIFGHOL_00579	5.33e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
NCIFGHOL_00580	8.71e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
NCIFGHOL_00581	7.05e-181	-	-	-	H	-	-	-	geranyltranstransferase activity
NCIFGHOL_00582	1.55e-224	-	-	-	-	-	-	-	-
NCIFGHOL_00583	1.8e-26	-	-	-	-	-	-	-	-
NCIFGHOL_00584	6.12e-149	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NCIFGHOL_00585	2.93e-237	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
NCIFGHOL_00586	1.56e-60	-	-	-	-	-	-	-	-
NCIFGHOL_00587	3.74e-123	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NCIFGHOL_00588	1.3e-96	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
NCIFGHOL_00589	1.93e-285	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
NCIFGHOL_00590	2.01e-108	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
NCIFGHOL_00591	4.32e-235	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
NCIFGHOL_00592	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NCIFGHOL_00593	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NCIFGHOL_00594	7.01e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
NCIFGHOL_00595	3.85e-167	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
NCIFGHOL_00596	2.67e-196	-	-	-	EG	-	-	-	EamA-like transporter family
NCIFGHOL_00597	1.63e-152	-	-	-	L	-	-	-	Integrase
NCIFGHOL_00598	5.95e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NCIFGHOL_00599	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_00601	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NCIFGHOL_00602	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NCIFGHOL_00603	8.01e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NCIFGHOL_00604	1.02e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCIFGHOL_00605	1.18e-204	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NCIFGHOL_00606	8.26e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NCIFGHOL_00607	9.53e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NCIFGHOL_00608	4.19e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NCIFGHOL_00609	5.61e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NCIFGHOL_00610	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NCIFGHOL_00611	5.91e-184	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NCIFGHOL_00612	2.67e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NCIFGHOL_00613	2.46e-171	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NCIFGHOL_00622	4.5e-73	-	-	-	-	-	-	-	-
NCIFGHOL_00623	1.76e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
NCIFGHOL_00624	8.4e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NCIFGHOL_00625	1.83e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NCIFGHOL_00626	4.22e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
NCIFGHOL_00627	4.78e-184	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NCIFGHOL_00628	2.71e-29	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NCIFGHOL_00635	4.97e-43	-	-	-	LM	-	-	-	gp58-like protein
NCIFGHOL_00636	1.39e-174	-	-	-	M	-	-	-	Prophage endopeptidase tail
NCIFGHOL_00637	1.7e-105	-	-	-	S	-	-	-	Phage tail protein
NCIFGHOL_00638	1.06e-307	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NCIFGHOL_00640	1.64e-12	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
NCIFGHOL_00641	2.44e-101	-	-	-	S	-	-	-	Phage tail tube protein
NCIFGHOL_00643	1e-41	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NCIFGHOL_00645	1.11e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NCIFGHOL_00646	1.95e-271	-	-	-	S	-	-	-	Phage capsid family
NCIFGHOL_00647	5.3e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NCIFGHOL_00648	1.74e-272	-	-	-	S	-	-	-	Phage portal protein
NCIFGHOL_00649	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NCIFGHOL_00650	9.68e-84	-	-	-	L	-	-	-	Phage terminase, small subunit
NCIFGHOL_00651	1.77e-91	-	-	-	L	-	-	-	HNH nucleases
NCIFGHOL_00658	4.73e-74	-	-	-	L	-	-	-	HNH nucleases
NCIFGHOL_00659	1.13e-82	-	-	-	L	-	-	-	Phage terminase, small subunit
NCIFGHOL_00660	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
NCIFGHOL_00661	6.41e-221	-	-	-	S	-	-	-	Phage portal protein
NCIFGHOL_00662	2.19e-104	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NCIFGHOL_00663	9.45e-226	-	-	-	S	-	-	-	Phage capsid family
NCIFGHOL_00664	8.31e-34	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NCIFGHOL_00665	1.97e-06	-	-	-	S	-	-	-	Phage head-tail joining protein
NCIFGHOL_00666	5.49e-50	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NCIFGHOL_00667	1.37e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
NCIFGHOL_00668	5.53e-149	-	-	-	S	-	-	-	Phage tail tube protein
NCIFGHOL_00669	1.14e-16	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
NCIFGHOL_00670	4.7e-128	-	-	-	S	-	-	-	EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
NCIFGHOL_00671	4.44e-98	-	-	-	S	-	-	-	Phage tail protein
NCIFGHOL_00672	6.03e-173	-	-	-	M	-	-	-	Prophage endopeptidase tail
NCIFGHOL_00673	1.28e-48	-	-	-	LM	-	-	-	gp58-like protein
NCIFGHOL_00680	7.46e-47	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NCIFGHOL_00681	2.92e-185	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NCIFGHOL_00682	6.57e-142	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NCIFGHOL_00683	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NCIFGHOL_00684	2.45e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
NCIFGHOL_00685	1.11e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NCIFGHOL_00686	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NCIFGHOL_00687	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NCIFGHOL_00688	1.33e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NCIFGHOL_00689	5.45e-202	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NCIFGHOL_00690	1.11e-184	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
NCIFGHOL_00691	2.32e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NCIFGHOL_00692	2.49e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NCIFGHOL_00693	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NCIFGHOL_00694	2.76e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NCIFGHOL_00695	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCIFGHOL_00697	1.02e-153	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NCIFGHOL_00698	8.84e-189	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NCIFGHOL_00699	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
NCIFGHOL_00700	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NCIFGHOL_00701	1.55e-150	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NCIFGHOL_00702	3.62e-179	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
NCIFGHOL_00703	7.59e-105	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NCIFGHOL_00704	6.25e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NCIFGHOL_00705	1.58e-128	-	-	-	S	-	-	-	glycosyl transferase family 2
NCIFGHOL_00706	2.82e-262	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
NCIFGHOL_00707	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NCIFGHOL_00708	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
NCIFGHOL_00709	2.45e-212	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
NCIFGHOL_00710	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NCIFGHOL_00711	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NCIFGHOL_00712	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NCIFGHOL_00714	0.0	-	-	-	M	-	-	-	family 8
NCIFGHOL_00715	0.0	-	-	-	M	-	-	-	family 8
NCIFGHOL_00716	6.83e-16	-	-	-	UW	-	-	-	Tetratricopeptide repeat
NCIFGHOL_00717	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NCIFGHOL_00718	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NCIFGHOL_00719	1.1e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NCIFGHOL_00720	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCIFGHOL_00721	3.21e-115	-	-	-	-	-	-	-	-
NCIFGHOL_00722	6.83e-50	-	-	-	-	-	-	-	-
NCIFGHOL_00723	2.26e-129	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NCIFGHOL_00724	2.77e-161	-	-	-	-	-	-	-	-
NCIFGHOL_00725	3.5e-84	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NCIFGHOL_00726	1.16e-220	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NCIFGHOL_00727	8.3e-179	epsB	-	-	M	-	-	-	biosynthesis protein
NCIFGHOL_00728	4.04e-147	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NCIFGHOL_00729	1.07e-119	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
NCIFGHOL_00730	3.4e-105	galnac-T15	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
NCIFGHOL_00731	1.49e-42	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NCIFGHOL_00732	4.34e-50	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCIFGHOL_00734	1.39e-105	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCIFGHOL_00735	7.48e-147	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NCIFGHOL_00736	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NCIFGHOL_00737	4.08e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NCIFGHOL_00738	5.67e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NCIFGHOL_00739	5.24e-259	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NCIFGHOL_00740	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NCIFGHOL_00741	1.15e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
NCIFGHOL_00742	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NCIFGHOL_00743	1.25e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NCIFGHOL_00744	5.6e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NCIFGHOL_00745	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_00746	2e-114	-	-	-	S	-	-	-	Protein conserved in bacteria
NCIFGHOL_00747	5.23e-233	-	-	-	-	-	-	-	-
NCIFGHOL_00748	4.87e-203	-	-	-	-	-	-	-	-
NCIFGHOL_00749	1.27e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NCIFGHOL_00750	5.71e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NCIFGHOL_00751	1.33e-98	-	-	-	S	-	-	-	Fic/DOC family
NCIFGHOL_00755	0.000991	ydiL	-	-	S	ko:K07052	-	ko00000	protease
NCIFGHOL_00758	1.79e-64	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NCIFGHOL_00760	3.66e-239	-	-	-	U	-	-	-	type IV secretory pathway VirB4
NCIFGHOL_00761	4.26e-35	-	-	-	-	-	-	-	-
NCIFGHOL_00763	1.9e-72	-	-	-	-	-	-	-	-
NCIFGHOL_00764	3.18e-279	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
NCIFGHOL_00769	5.37e-178	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NCIFGHOL_00772	1.48e-180	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
NCIFGHOL_00773	2.04e-61	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
NCIFGHOL_00774	2.16e-13	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NCIFGHOL_00777	1.66e-19	-	-	-	K	-	-	-	ORF6N domain
NCIFGHOL_00778	7.53e-35	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
NCIFGHOL_00781	8.64e-43	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NCIFGHOL_00782	1.29e-172	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NCIFGHOL_00783	3.95e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NCIFGHOL_00784	2.48e-66	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NCIFGHOL_00785	9.05e-05	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
NCIFGHOL_00805	3.15e-108	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
NCIFGHOL_00809	4.05e-34	-	-	-	-	-	-	-	-
NCIFGHOL_00811	6.25e-54	-	-	-	S	-	-	-	HNH endonuclease
NCIFGHOL_00814	3.52e-175	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_00815	4.69e-112	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NCIFGHOL_00816	2.6e-185	-	-	-	L	-	-	-	DnaD domain protein
NCIFGHOL_00819	7.77e-26	-	-	-	-	-	-	-	-
NCIFGHOL_00824	1.1e-27	-	-	-	-	-	-	-	-
NCIFGHOL_00825	7.27e-46	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NCIFGHOL_00830	5.07e-14	-	-	-	M	-	-	-	LysM domain
NCIFGHOL_00832	2.51e-15	-	-	-	-	-	-	-	-
NCIFGHOL_00833	7.78e-151	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_00835	1.94e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NCIFGHOL_00836	3.38e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NCIFGHOL_00837	1.14e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
NCIFGHOL_00838	3.3e-25	-	-	-	-	-	-	-	-
NCIFGHOL_00839	1.72e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NCIFGHOL_00840	4.17e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NCIFGHOL_00841	3.75e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NCIFGHOL_00842	4.95e-51	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NCIFGHOL_00843	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCIFGHOL_00844	2.49e-195	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NCIFGHOL_00845	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NCIFGHOL_00847	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NCIFGHOL_00848	1.81e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NCIFGHOL_00849	1.18e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
NCIFGHOL_00850	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
NCIFGHOL_00851	3.5e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCIFGHOL_00852	5.94e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCIFGHOL_00853	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NCIFGHOL_00854	3.66e-186	-	-	-	S	-	-	-	DUF218 domain
NCIFGHOL_00855	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NCIFGHOL_00856	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
NCIFGHOL_00857	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NCIFGHOL_00858	1.44e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NCIFGHOL_00859	6.68e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
NCIFGHOL_00860	2.18e-69	-	-	-	S	-	-	-	Cupin domain
NCIFGHOL_00861	2.3e-106	-	-	-	C	-	-	-	Flavodoxin
NCIFGHOL_00862	2.23e-203	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
NCIFGHOL_00863	1.66e-215	yvgN	-	-	C	-	-	-	Aldo keto reductase
NCIFGHOL_00864	8.4e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NCIFGHOL_00865	6.06e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NCIFGHOL_00866	1.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NCIFGHOL_00867	1.21e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
NCIFGHOL_00868	4.89e-201	gspA	-	-	M	-	-	-	family 8
NCIFGHOL_00869	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NCIFGHOL_00870	6.11e-111	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NCIFGHOL_00873	1.7e-63	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
NCIFGHOL_00875	0.0	-	-	-	-	-	-	-	-
NCIFGHOL_00876	0.0	-	-	-	-	-	-	-	-
NCIFGHOL_00877	5.6e-158	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NCIFGHOL_00878	1.23e-134	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NCIFGHOL_00879	3.69e-92	-	-	-	-	-	-	-	-
NCIFGHOL_00880	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NCIFGHOL_00881	1.19e-134	-	-	-	L	-	-	-	nuclease
NCIFGHOL_00884	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NCIFGHOL_00885	4.8e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NCIFGHOL_00886	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NCIFGHOL_00887	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NCIFGHOL_00888	3.44e-208	-	-	-	EG	-	-	-	EamA-like transporter family
NCIFGHOL_00889	4.11e-160	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NCIFGHOL_00890	2.71e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NCIFGHOL_00891	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NCIFGHOL_00892	1.04e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NCIFGHOL_00893	2.97e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NCIFGHOL_00894	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NCIFGHOL_00895	4.42e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NCIFGHOL_00896	3.35e-121	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NCIFGHOL_00897	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NCIFGHOL_00898	7.8e-238	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
NCIFGHOL_00899	1.73e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NCIFGHOL_00900	1.68e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NCIFGHOL_00901	3.6e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
NCIFGHOL_00902	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
NCIFGHOL_00903	9.7e-168	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
NCIFGHOL_00904	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
NCIFGHOL_00905	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
NCIFGHOL_00906	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NCIFGHOL_00907	1.52e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NCIFGHOL_00908	9.71e-50	-	-	-	S	-	-	-	Cytochrome B5
NCIFGHOL_00909	6.38e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NCIFGHOL_00910	6.68e-206	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NCIFGHOL_00911	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NCIFGHOL_00912	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NCIFGHOL_00913	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NCIFGHOL_00914	6.13e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NCIFGHOL_00915	1.17e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NCIFGHOL_00916	4.46e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NCIFGHOL_00917	1.65e-41	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
NCIFGHOL_00918	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NCIFGHOL_00919	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NCIFGHOL_00920	4.03e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NCIFGHOL_00921	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NCIFGHOL_00922	2.66e-137	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
NCIFGHOL_00923	4.87e-262	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NCIFGHOL_00924	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NCIFGHOL_00925	1.05e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
NCIFGHOL_00926	7.5e-100	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NCIFGHOL_00927	2.32e-280	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NCIFGHOL_00928	2.67e-121	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
NCIFGHOL_00929	9.94e-227	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCIFGHOL_00930	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_00932	1.26e-172	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NCIFGHOL_00933	2.8e-169	-	-	-	F	-	-	-	NUDIX domain
NCIFGHOL_00934	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NCIFGHOL_00935	9.36e-131	pncA	-	-	Q	-	-	-	Isochorismatase family
NCIFGHOL_00936	1.58e-264	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NCIFGHOL_00937	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
NCIFGHOL_00938	2.25e-208	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
NCIFGHOL_00939	3.58e-51	hxlR	-	-	K	-	-	-	regulation of RNA biosynthetic process
NCIFGHOL_00940	2.03e-307	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
NCIFGHOL_00941	3.5e-167	-	-	-	IQ	-	-	-	dehydrogenase reductase
NCIFGHOL_00942	2.25e-49	-	-	-	-	-	-	-	-
NCIFGHOL_00943	1.34e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NCIFGHOL_00944	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
NCIFGHOL_00945	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NCIFGHOL_00946	9.76e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NCIFGHOL_00948	9.02e-128	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NCIFGHOL_00949	6.25e-83	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NCIFGHOL_00950	5.03e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCIFGHOL_00952	6.6e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
NCIFGHOL_00953	2.64e-109	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
NCIFGHOL_00954	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NCIFGHOL_00956	7.42e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NCIFGHOL_00957	1.52e-68	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NCIFGHOL_00958	4.11e-160	-	-	-	-	-	-	-	-
NCIFGHOL_00959	1.01e-165	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NCIFGHOL_00960	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NCIFGHOL_00961	2.28e-272	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
NCIFGHOL_00962	4.44e-11	-	-	-	-	-	-	-	-
NCIFGHOL_00963	9.46e-200	-	-	-	GM	-	-	-	NAD(P)H-binding
NCIFGHOL_00964	3.87e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_00965	2.16e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
NCIFGHOL_00966	2.74e-138	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NCIFGHOL_00967	2.13e-182	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_00968	6.03e-133	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NCIFGHOL_00969	1.82e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NCIFGHOL_00970	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NCIFGHOL_00971	7.15e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NCIFGHOL_00972	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NCIFGHOL_00973	1.72e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NCIFGHOL_00974	6.16e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NCIFGHOL_00975	3.62e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NCIFGHOL_00976	2.82e-279	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
NCIFGHOL_00977	1.78e-57	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
NCIFGHOL_00978	3.44e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NCIFGHOL_00979	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
NCIFGHOL_00980	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NCIFGHOL_00982	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NCIFGHOL_00983	0.0	-	-	-	L	-	-	-	DNA helicase
NCIFGHOL_00984	4.08e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NCIFGHOL_00985	1.14e-229	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NCIFGHOL_00986	2.16e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NCIFGHOL_00987	1.53e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NCIFGHOL_00988	4.1e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NCIFGHOL_00989	2.47e-224	-	-	-	-	-	-	-	-
NCIFGHOL_00990	2.4e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NCIFGHOL_00992	2.25e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NCIFGHOL_00993	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NCIFGHOL_00994	1.03e-197	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NCIFGHOL_00995	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NCIFGHOL_00996	5.08e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NCIFGHOL_00997	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NCIFGHOL_00999	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NCIFGHOL_01000	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NCIFGHOL_01001	1.14e-313	yycH	-	-	S	-	-	-	YycH protein
NCIFGHOL_01002	1.44e-192	yycI	-	-	S	-	-	-	YycH protein
NCIFGHOL_01003	4.35e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NCIFGHOL_01004	7.05e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NCIFGHOL_01005	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NCIFGHOL_01006	1.58e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NCIFGHOL_01007	2.78e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NCIFGHOL_01008	1.21e-94	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NCIFGHOL_01009	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NCIFGHOL_01010	1.88e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NCIFGHOL_01011	8.43e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NCIFGHOL_01012	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
NCIFGHOL_01013	7.61e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NCIFGHOL_01014	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
NCIFGHOL_01015	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
NCIFGHOL_01016	3.25e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NCIFGHOL_01017	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NCIFGHOL_01018	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NCIFGHOL_01019	4.15e-177	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NCIFGHOL_01020	1.29e-10	-	-	-	S	-	-	-	Membrane
NCIFGHOL_01021	4.58e-150	-	-	-	S	-	-	-	Membrane
NCIFGHOL_01022	4.73e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
NCIFGHOL_01023	3.42e-29	-	-	-	-	-	-	-	-
NCIFGHOL_01024	1.01e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NCIFGHOL_01025	7.66e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NCIFGHOL_01026	5.13e-61	-	-	-	-	-	-	-	-
NCIFGHOL_01027	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
NCIFGHOL_01028	2.82e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
NCIFGHOL_01029	4.68e-198	yvgN	-	-	S	-	-	-	Aldo keto reductase
NCIFGHOL_01030	2.11e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NCIFGHOL_01031	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NCIFGHOL_01032	3.16e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NCIFGHOL_01033	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
NCIFGHOL_01034	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NCIFGHOL_01035	6.61e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NCIFGHOL_01036	2.21e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NCIFGHOL_01037	8.55e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NCIFGHOL_01038	1.35e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NCIFGHOL_01039	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NCIFGHOL_01040	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NCIFGHOL_01041	1e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCIFGHOL_01042	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NCIFGHOL_01043	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01044	1.36e-101	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
NCIFGHOL_01045	2.4e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NCIFGHOL_01046	1.78e-10	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NCIFGHOL_01054	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_01055	2.4e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NCIFGHOL_01056	1.36e-101	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
NCIFGHOL_01059	2.4e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NCIFGHOL_01060	1.36e-101	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
NCIFGHOL_01061	1.06e-25	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
NCIFGHOL_01062	1.19e-251	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NCIFGHOL_01063	1.63e-159	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NCIFGHOL_01064	1.12e-214	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NCIFGHOL_01065	2.4e-49	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NCIFGHOL_01066	1.36e-101	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
NCIFGHOL_01067	6.53e-237	-	-	-	S	-	-	-	Peptidase, M23
NCIFGHOL_01068	0.0	-	-	-	S	-	-	-	Peptidase, M23
NCIFGHOL_01069	0.0	-	-	-	M	-	-	-	NlpC/P60 family
NCIFGHOL_01070	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NCIFGHOL_01071	1.68e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NCIFGHOL_01072	2.63e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
NCIFGHOL_01073	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
NCIFGHOL_01074	2.16e-130	-	-	-	-	-	-	-	-
NCIFGHOL_01076	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NCIFGHOL_01077	1.28e-75	-	-	-	-	-	-	-	-
NCIFGHOL_01079	5.22e-112	-	-	-	-	-	-	-	-
NCIFGHOL_01080	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NCIFGHOL_01081	8.97e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
NCIFGHOL_01082	1.53e-71	-	-	-	S	-	-	-	Cupredoxin-like domain
NCIFGHOL_01083	4.52e-208	-	-	-	EG	-	-	-	EamA-like transporter family
NCIFGHOL_01084	1.95e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
NCIFGHOL_01085	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NCIFGHOL_01086	7.49e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
NCIFGHOL_01087	3.63e-35	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NCIFGHOL_01089	2.69e-36	-	-	-	-	-	-	-	-
NCIFGHOL_01090	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NCIFGHOL_01091	1.65e-151	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NCIFGHOL_01092	9.07e-199	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NCIFGHOL_01093	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NCIFGHOL_01094	2.81e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NCIFGHOL_01096	5.74e-107	lytE	-	-	M	-	-	-	Lysin motif
NCIFGHOL_01097	5.46e-191	-	-	-	S	-	-	-	Cof-like hydrolase
NCIFGHOL_01098	4.03e-99	-	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_01099	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NCIFGHOL_01100	1.01e-67	-	-	-	-	-	-	-	-
NCIFGHOL_01101	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NCIFGHOL_01102	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NCIFGHOL_01103	1.5e-162	ybbR	-	-	S	-	-	-	YbbR-like protein
NCIFGHOL_01104	1.61e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NCIFGHOL_01105	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
NCIFGHOL_01106	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NCIFGHOL_01107	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCIFGHOL_01108	7.58e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NCIFGHOL_01109	1.51e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NCIFGHOL_01110	2.92e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NCIFGHOL_01111	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NCIFGHOL_01112	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NCIFGHOL_01113	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NCIFGHOL_01114	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCIFGHOL_01115	1.36e-136	-	-	-	-	-	-	-	-
NCIFGHOL_01116	3.72e-211	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NCIFGHOL_01117	1.45e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NCIFGHOL_01118	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NCIFGHOL_01119	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NCIFGHOL_01120	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NCIFGHOL_01121	1.84e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
NCIFGHOL_01122	0.0	yhaN	-	-	L	-	-	-	AAA domain
NCIFGHOL_01123	4.08e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NCIFGHOL_01125	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NCIFGHOL_01126	6.62e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01127	1.63e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NCIFGHOL_01128	6.19e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NCIFGHOL_01129	2.22e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NCIFGHOL_01130	1.47e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NCIFGHOL_01131	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
NCIFGHOL_01132	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
NCIFGHOL_01133	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NCIFGHOL_01134	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NCIFGHOL_01135	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NCIFGHOL_01136	5.87e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NCIFGHOL_01137	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NCIFGHOL_01138	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NCIFGHOL_01139	1.51e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NCIFGHOL_01140	2.71e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NCIFGHOL_01141	1.64e-299	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NCIFGHOL_01142	6.77e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NCIFGHOL_01143	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NCIFGHOL_01144	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NCIFGHOL_01145	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NCIFGHOL_01146	2.23e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NCIFGHOL_01147	7.72e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NCIFGHOL_01148	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NCIFGHOL_01149	8.13e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NCIFGHOL_01150	1.03e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NCIFGHOL_01151	1.56e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NCIFGHOL_01152	2.14e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
NCIFGHOL_01153	9.54e-265	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NCIFGHOL_01154	5.84e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NCIFGHOL_01155	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NCIFGHOL_01156	5.62e-155	csrR	-	-	K	-	-	-	response regulator
NCIFGHOL_01157	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NCIFGHOL_01158	0.0	potE	-	-	E	-	-	-	Amino Acid
NCIFGHOL_01159	1.61e-292	-	-	-	V	-	-	-	MatE
NCIFGHOL_01160	1.52e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NCIFGHOL_01161	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NCIFGHOL_01162	6.76e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NCIFGHOL_01163	6.64e-187	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCIFGHOL_01164	8.85e-118	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NCIFGHOL_01165	1.17e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NCIFGHOL_01166	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NCIFGHOL_01167	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NCIFGHOL_01168	2.94e-149	-	-	-	M	-	-	-	PFAM NLP P60 protein
NCIFGHOL_01169	4.85e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NCIFGHOL_01170	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCIFGHOL_01171	2.49e-87	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NCIFGHOL_01172	0.0	-	-	-	S	-	-	-	membrane
NCIFGHOL_01173	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NCIFGHOL_01174	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NCIFGHOL_01175	3.96e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NCIFGHOL_01176	2.99e-141	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NCIFGHOL_01177	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NCIFGHOL_01178	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NCIFGHOL_01179	4.44e-87	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NCIFGHOL_01180	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NCIFGHOL_01181	4.43e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NCIFGHOL_01182	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NCIFGHOL_01183	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NCIFGHOL_01184	1.57e-278	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NCIFGHOL_01185	1.28e-18	-	-	-	-	-	-	-	-
NCIFGHOL_01186	6.9e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NCIFGHOL_01188	5.14e-93	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_01190	1.14e-07	-	-	-	K	-	-	-	Peptidase S24-like
NCIFGHOL_01193	6.49e-13	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCIFGHOL_01197	3.73e-22	-	-	-	-	-	-	-	-
NCIFGHOL_01199	7e-10	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NCIFGHOL_01211	0.000773	-	-	-	S	-	-	-	YopX protein
NCIFGHOL_01219	1.3e-21	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
NCIFGHOL_01228	2.25e-62	-	-	-	L	-	-	-	four-way junction helicase activity
NCIFGHOL_01230	5.13e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NCIFGHOL_01231	5.9e-14	-	-	-	T	-	-	-	SpoVT / AbrB like domain
NCIFGHOL_01234	2.08e-82	-	-	-	-	-	-	-	-
NCIFGHOL_01237	3.44e-13	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NCIFGHOL_01239	1.88e-115	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_01240	4.91e-80	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NCIFGHOL_01241	3.34e-288	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NCIFGHOL_01242	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NCIFGHOL_01243	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NCIFGHOL_01244	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
NCIFGHOL_01245	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCIFGHOL_01246	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NCIFGHOL_01247	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCIFGHOL_01248	5.72e-239	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NCIFGHOL_01249	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCIFGHOL_01250	6.28e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NCIFGHOL_01251	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NCIFGHOL_01252	4.18e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NCIFGHOL_01253	9.6e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NCIFGHOL_01254	2.66e-120	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NCIFGHOL_01255	1.21e-143	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NCIFGHOL_01256	5.31e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCIFGHOL_01257	5.09e-186	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NCIFGHOL_01259	1.88e-91	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
NCIFGHOL_01260	2.38e-56	-	-	-	-	-	-	-	-
NCIFGHOL_01261	1.43e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
NCIFGHOL_01262	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NCIFGHOL_01263	1.57e-235	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NCIFGHOL_01264	5.92e-235	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NCIFGHOL_01265	2.88e-167	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NCIFGHOL_01266	4.02e-179	-	-	-	-	-	-	-	-
NCIFGHOL_01267	4.66e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NCIFGHOL_01268	1.21e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NCIFGHOL_01269	2.14e-74	-	-	-	-	-	-	-	-
NCIFGHOL_01270	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NCIFGHOL_01271	4.38e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NCIFGHOL_01272	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NCIFGHOL_01273	6.01e-99	ykuL	-	-	S	-	-	-	(CBS) domain
NCIFGHOL_01274	5.52e-119	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NCIFGHOL_01275	4.73e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NCIFGHOL_01276	1.23e-182	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NCIFGHOL_01277	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NCIFGHOL_01278	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NCIFGHOL_01279	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NCIFGHOL_01280	1.02e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
NCIFGHOL_01281	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NCIFGHOL_01282	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NCIFGHOL_01283	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NCIFGHOL_01284	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NCIFGHOL_01285	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NCIFGHOL_01286	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NCIFGHOL_01287	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NCIFGHOL_01288	1.66e-246	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NCIFGHOL_01289	1.16e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NCIFGHOL_01290	6.16e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NCIFGHOL_01291	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NCIFGHOL_01292	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NCIFGHOL_01293	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NCIFGHOL_01294	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NCIFGHOL_01295	1.01e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NCIFGHOL_01296	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NCIFGHOL_01297	2.8e-195	-	-	-	S	-	-	-	Helix-turn-helix domain
NCIFGHOL_01298	8.66e-316	ymfH	-	-	S	-	-	-	Peptidase M16
NCIFGHOL_01299	1.75e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NCIFGHOL_01300	3.32e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NCIFGHOL_01301	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01302	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NCIFGHOL_01303	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NCIFGHOL_01304	3.67e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NCIFGHOL_01305	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NCIFGHOL_01306	3.6e-158	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NCIFGHOL_01307	2.9e-310	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NCIFGHOL_01308	1.09e-295	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NCIFGHOL_01309	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NCIFGHOL_01310	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NCIFGHOL_01311	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NCIFGHOL_01312	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NCIFGHOL_01313	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NCIFGHOL_01314	1.37e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NCIFGHOL_01315	4.79e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NCIFGHOL_01316	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NCIFGHOL_01317	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NCIFGHOL_01318	1.13e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NCIFGHOL_01319	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NCIFGHOL_01320	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NCIFGHOL_01321	2.78e-71	-	-	-	-	-	-	-	-
NCIFGHOL_01322	8.25e-166	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NCIFGHOL_01323	8.38e-232	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NCIFGHOL_01324	3.36e-77	-	-	-	-	-	-	-	-
NCIFGHOL_01326	1.49e-54	-	-	-	-	-	-	-	-
NCIFGHOL_01327	1.88e-60	-	-	-	-	-	-	-	-
NCIFGHOL_01328	3.36e-270	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
NCIFGHOL_01329	2.44e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
NCIFGHOL_01330	3.32e-284	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NCIFGHOL_01331	9.63e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
NCIFGHOL_01332	2.16e-119	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NCIFGHOL_01333	5.83e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NCIFGHOL_01334	2.67e-92	-	-	-	-	-	-	-	-
NCIFGHOL_01336	9.17e-59	-	-	-	-	-	-	-	-
NCIFGHOL_01337	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01338	7.94e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NCIFGHOL_01339	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NCIFGHOL_01340	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NCIFGHOL_01341	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01342	3.8e-63	-	-	-	-	-	-	-	-
NCIFGHOL_01343	1.81e-41	-	-	-	-	-	-	-	-
NCIFGHOL_01344	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NCIFGHOL_01345	1.26e-60	-	-	-	-	-	-	-	-
NCIFGHOL_01346	4.71e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NCIFGHOL_01347	1.39e-127	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NCIFGHOL_01348	0.0	-	-	-	L	-	-	-	PLD-like domain
NCIFGHOL_01350	2.04e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
NCIFGHOL_01351	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01352	9.72e-293	-	-	-	P	-	-	-	Chloride transporter, ClC family
NCIFGHOL_01353	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NCIFGHOL_01354	1.62e-142	-	-	-	I	-	-	-	Acid phosphatase homologues
NCIFGHOL_01356	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01357	1.11e-158	citR	-	-	K	-	-	-	sugar-binding domain protein
NCIFGHOL_01358	9.44e-223	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NCIFGHOL_01359	2.31e-188	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NCIFGHOL_01360	2.56e-56	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
NCIFGHOL_01361	3.29e-204	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NCIFGHOL_01362	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
NCIFGHOL_01363	5.47e-194	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NCIFGHOL_01364	5.1e-143	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NCIFGHOL_01365	1.7e-203	-	-	-	K	-	-	-	LysR family
NCIFGHOL_01366	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NCIFGHOL_01367	7.76e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
NCIFGHOL_01368	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_01369	7.53e-239	-	-	-	I	-	-	-	Alpha beta
NCIFGHOL_01370	4.59e-133	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NCIFGHOL_01371	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCIFGHOL_01373	2.17e-208	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NCIFGHOL_01374	9.49e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NCIFGHOL_01375	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NCIFGHOL_01376	1.26e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NCIFGHOL_01377	4.03e-75	-	-	-	-	-	-	-	-
NCIFGHOL_01378	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCIFGHOL_01379	3.69e-278	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NCIFGHOL_01380	8.58e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NCIFGHOL_01381	3.03e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NCIFGHOL_01382	1.57e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NCIFGHOL_01383	1.14e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01384	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NCIFGHOL_01385	4.16e-140	-	-	-	S	-	-	-	VIT family
NCIFGHOL_01386	7.33e-152	-	-	-	S	-	-	-	membrane
NCIFGHOL_01387	2.34e-211	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NCIFGHOL_01388	5.46e-160	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NCIFGHOL_01389	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NCIFGHOL_01390	1.41e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
NCIFGHOL_01391	1.06e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NCIFGHOL_01392	1.55e-150	-	-	-	I	-	-	-	phosphatase
NCIFGHOL_01393	1.69e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NCIFGHOL_01394	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NCIFGHOL_01395	1.57e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NCIFGHOL_01401	2.6e-144	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NCIFGHOL_01402	1.62e-132	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
NCIFGHOL_01403	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NCIFGHOL_01404	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NCIFGHOL_01405	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NCIFGHOL_01406	5.99e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NCIFGHOL_01407	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCIFGHOL_01408	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCIFGHOL_01409	1.06e-259	-	-	-	-	-	-	-	-
NCIFGHOL_01410	2.53e-140	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NCIFGHOL_01411	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NCIFGHOL_01412	2.4e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NCIFGHOL_01413	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NCIFGHOL_01414	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NCIFGHOL_01415	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NCIFGHOL_01416	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NCIFGHOL_01417	1.04e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NCIFGHOL_01418	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NCIFGHOL_01419	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NCIFGHOL_01420	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NCIFGHOL_01421	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NCIFGHOL_01422	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NCIFGHOL_01423	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NCIFGHOL_01424	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NCIFGHOL_01425	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NCIFGHOL_01426	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NCIFGHOL_01427	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NCIFGHOL_01428	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCIFGHOL_01429	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NCIFGHOL_01430	8.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NCIFGHOL_01431	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NCIFGHOL_01432	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NCIFGHOL_01433	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NCIFGHOL_01434	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NCIFGHOL_01435	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NCIFGHOL_01436	1.51e-159	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NCIFGHOL_01437	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NCIFGHOL_01438	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NCIFGHOL_01439	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NCIFGHOL_01440	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NCIFGHOL_01441	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCIFGHOL_01442	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NCIFGHOL_01443	1.95e-183	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCIFGHOL_01444	4.63e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCIFGHOL_01445	4.99e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCIFGHOL_01446	5.41e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NCIFGHOL_01447	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_01448	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01449	2.39e-64	-	-	-	-	-	-	-	-
NCIFGHOL_01451	1.2e-64	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NCIFGHOL_01452	1.14e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NCIFGHOL_01453	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NCIFGHOL_01454	5.37e-169	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NCIFGHOL_01455	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NCIFGHOL_01456	9.35e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCIFGHOL_01457	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCIFGHOL_01458	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NCIFGHOL_01459	3.59e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NCIFGHOL_01460	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCIFGHOL_01461	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NCIFGHOL_01462	1.41e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NCIFGHOL_01463	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NCIFGHOL_01464	3.41e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NCIFGHOL_01465	1.64e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NCIFGHOL_01466	1.11e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NCIFGHOL_01467	2.51e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NCIFGHOL_01468	8.11e-203	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NCIFGHOL_01469	4.11e-174	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NCIFGHOL_01470	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NCIFGHOL_01471	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NCIFGHOL_01472	7.61e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NCIFGHOL_01473	7.03e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NCIFGHOL_01474	7.65e-164	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NCIFGHOL_01475	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NCIFGHOL_01476	1.18e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NCIFGHOL_01477	7.29e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NCIFGHOL_01478	8.95e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NCIFGHOL_01479	6.03e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NCIFGHOL_01480	3.82e-183	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NCIFGHOL_01481	2.65e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NCIFGHOL_01482	4.85e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NCIFGHOL_01483	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NCIFGHOL_01484	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NCIFGHOL_01486	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NCIFGHOL_01487	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NCIFGHOL_01488	2.86e-102	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NCIFGHOL_01489	0.0	-	-	-	E	-	-	-	amino acid
NCIFGHOL_01490	0.0	ydaO	-	-	E	-	-	-	amino acid
NCIFGHOL_01491	1.78e-51	-	-	-	-	-	-	-	-
NCIFGHOL_01492	1.52e-87	-	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_01493	6.63e-216	-	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_01494	3.69e-142	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NCIFGHOL_01495	1.76e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NCIFGHOL_01496	1.32e-151	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NCIFGHOL_01497	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NCIFGHOL_01498	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NCIFGHOL_01499	6.16e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NCIFGHOL_01500	3e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NCIFGHOL_01501	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NCIFGHOL_01502	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NCIFGHOL_01503	1.41e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NCIFGHOL_01504	6.63e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NCIFGHOL_01505	7.6e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NCIFGHOL_01506	4.31e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NCIFGHOL_01507	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NCIFGHOL_01508	1.47e-203	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NCIFGHOL_01509	8.29e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NCIFGHOL_01510	8.11e-263	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NCIFGHOL_01511	2e-206	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
NCIFGHOL_01512	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NCIFGHOL_01513	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NCIFGHOL_01514	4.17e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NCIFGHOL_01515	1.03e-19	-	-	-	-	-	-	-	-
NCIFGHOL_01516	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NCIFGHOL_01517	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NCIFGHOL_01518	9.18e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NCIFGHOL_01519	9.4e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NCIFGHOL_01520	2.43e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NCIFGHOL_01521	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NCIFGHOL_01523	1.83e-21	-	-	-	-	-	-	-	-
NCIFGHOL_01524	1.37e-306	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
NCIFGHOL_01525	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NCIFGHOL_01527	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NCIFGHOL_01528	4.41e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NCIFGHOL_01529	2.4e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCIFGHOL_01530	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NCIFGHOL_01531	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NCIFGHOL_01532	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NCIFGHOL_01533	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NCIFGHOL_01534	7.76e-186	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NCIFGHOL_01535	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NCIFGHOL_01536	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NCIFGHOL_01537	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01538	4.89e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NCIFGHOL_01539	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NCIFGHOL_01540	7.9e-307	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NCIFGHOL_01541	1.23e-194	yeaE	-	-	S	-	-	-	Aldo keto
NCIFGHOL_01542	4.45e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NCIFGHOL_01543	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
NCIFGHOL_01544	3.77e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCIFGHOL_01545	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NCIFGHOL_01546	7.03e-33	-	-	-	-	-	-	-	-
NCIFGHOL_01547	1.93e-132	-	-	-	V	-	-	-	VanZ like family
NCIFGHOL_01548	6.7e-301	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NCIFGHOL_01549	1.46e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NCIFGHOL_01550	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_01551	1.56e-121	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NCIFGHOL_01552	4.5e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NCIFGHOL_01553	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NCIFGHOL_01554	5.07e-56	-	-	-	-	-	-	-	-
NCIFGHOL_01555	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NCIFGHOL_01556	8.34e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NCIFGHOL_01557	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NCIFGHOL_01558	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NCIFGHOL_01559	2.97e-229	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCIFGHOL_01560	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NCIFGHOL_01561	2.54e-145	-	-	-	-	-	-	-	-
NCIFGHOL_01562	4e-235	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NCIFGHOL_01563	5.7e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCIFGHOL_01564	1.78e-42	-	-	-	-	-	-	-	-
NCIFGHOL_01565	1.22e-150	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NCIFGHOL_01573	1.43e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NCIFGHOL_01574	6.49e-306	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NCIFGHOL_01575	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NCIFGHOL_01576	9.29e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NCIFGHOL_01577	9.74e-199	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
NCIFGHOL_01578	7.1e-143	-	-	-	M	-	-	-	LysM domain protein
NCIFGHOL_01579	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
NCIFGHOL_01580	1.01e-140	-	-	-	M	-	-	-	LysM domain protein
NCIFGHOL_01581	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
NCIFGHOL_01582	3.19e-38	-	-	-	-	-	-	-	-
NCIFGHOL_01583	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NCIFGHOL_01584	3.64e-59	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NCIFGHOL_01585	3.02e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NCIFGHOL_01586	8.02e-271	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NCIFGHOL_01587	2.14e-94	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
NCIFGHOL_01588	2.02e-144	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NCIFGHOL_01589	5.22e-123	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCIFGHOL_01590	1.88e-120	cps3F	-	-	-	-	-	-	-
NCIFGHOL_01591	6.58e-48	-	-	-	M	-	-	-	biosynthesis protein
NCIFGHOL_01592	1.29e-105	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NCIFGHOL_01593	1.08e-110	-	-	-	S	-	-	-	Glycosyltransferase like family
NCIFGHOL_01594	1.18e-139	-	-	-	-	-	-	-	-
NCIFGHOL_01595	3.23e-175	-	-	-	M	-	-	-	Glycosyl transferase family 2
NCIFGHOL_01597	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCIFGHOL_01598	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
NCIFGHOL_01599	4.01e-153	-	-	-	M	-	-	-	Bacterial sugar transferase
NCIFGHOL_01600	3.8e-223	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NCIFGHOL_01601	6.67e-190	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NCIFGHOL_01602	4.43e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NCIFGHOL_01603	7.27e-42	-	-	-	-	-	-	-	-
NCIFGHOL_01604	7.29e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NCIFGHOL_01605	2.13e-198	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NCIFGHOL_01606	0.0	potE	-	-	E	-	-	-	Amino Acid
NCIFGHOL_01607	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NCIFGHOL_01608	6.88e-281	arcT	-	-	E	-	-	-	Aminotransferase
NCIFGHOL_01609	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NCIFGHOL_01610	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NCIFGHOL_01611	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NCIFGHOL_01612	1.16e-263	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NCIFGHOL_01614	1.34e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NCIFGHOL_01615	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
NCIFGHOL_01616	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NCIFGHOL_01617	2.95e-135	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NCIFGHOL_01618	8.81e-212	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NCIFGHOL_01619	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NCIFGHOL_01620	6.21e-245	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NCIFGHOL_01621	1.85e-104	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
NCIFGHOL_01622	1.59e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NCIFGHOL_01623	5.85e-257	-	-	-	P	-	-	-	Major Facilitator Superfamily
NCIFGHOL_01624	1.55e-26	-	-	-	-	-	-	-	-
NCIFGHOL_01625	3.51e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
NCIFGHOL_01626	3.61e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NCIFGHOL_01627	7.88e-215	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
NCIFGHOL_01628	6e-217	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
NCIFGHOL_01629	2.15e-158	pnb	-	-	C	-	-	-	nitroreductase
NCIFGHOL_01630	1.75e-118	-	-	-	-	-	-	-	-
NCIFGHOL_01631	6.3e-105	yvbK	-	-	K	-	-	-	GNAT family
NCIFGHOL_01632	1.89e-316	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
NCIFGHOL_01633	1.54e-269	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NCIFGHOL_01635	5.84e-66	-	-	-	-	-	-	-	-
NCIFGHOL_01636	2.14e-36	-	-	-	S	-	-	-	PFAM Archaeal ATPase
NCIFGHOL_01637	2.09e-56	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NCIFGHOL_01638	4.26e-204	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
NCIFGHOL_01641	7.75e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NCIFGHOL_01642	5.03e-128	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NCIFGHOL_01643	2.79e-49	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	PFAM Heavy metal transport detoxification protein
NCIFGHOL_01644	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
NCIFGHOL_01645	4.13e-77	-	-	-	K	-	-	-	transcriptional regulator
NCIFGHOL_01646	5.93e-55	-	-	-	K	-	-	-	transcriptional regulator
NCIFGHOL_01647	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NCIFGHOL_01648	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NCIFGHOL_01649	0.0	-	-	-	M	-	-	-	domain protein
NCIFGHOL_01650	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
NCIFGHOL_01651	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NCIFGHOL_01652	8.53e-95	-	-	-	-	-	-	-	-
NCIFGHOL_01653	8.37e-145	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NCIFGHOL_01655	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NCIFGHOL_01656	1.42e-120	-	-	-	-	-	-	-	-
NCIFGHOL_01657	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NCIFGHOL_01658	1.46e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NCIFGHOL_01659	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NCIFGHOL_01660	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NCIFGHOL_01661	3.72e-217	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NCIFGHOL_01662	8.95e-168	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NCIFGHOL_01663	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NCIFGHOL_01664	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NCIFGHOL_01665	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NCIFGHOL_01666	1.06e-204	mleR	-	-	K	-	-	-	LysR family
NCIFGHOL_01667	6.76e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NCIFGHOL_01668	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
NCIFGHOL_01669	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
NCIFGHOL_01670	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NCIFGHOL_01673	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NCIFGHOL_01674	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NCIFGHOL_01675	7.29e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NCIFGHOL_01676	1.62e-312	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NCIFGHOL_01677	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NCIFGHOL_01678	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NCIFGHOL_01679	1.62e-91	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NCIFGHOL_01680	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NCIFGHOL_01681	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NCIFGHOL_01682	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NCIFGHOL_01683	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCIFGHOL_01684	8.79e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NCIFGHOL_01685	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NCIFGHOL_01686	2.43e-264	yacL	-	-	S	-	-	-	domain protein
NCIFGHOL_01687	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NCIFGHOL_01688	1.39e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NCIFGHOL_01689	4.04e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NCIFGHOL_01690	3.41e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NCIFGHOL_01691	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NCIFGHOL_01692	3.01e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NCIFGHOL_01693	1.95e-170	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01694	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NCIFGHOL_01695	4.28e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NCIFGHOL_01696	2.55e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NCIFGHOL_01697	6.14e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCIFGHOL_01698	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NCIFGHOL_01699	1.51e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NCIFGHOL_01700	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NCIFGHOL_01702	9.18e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NCIFGHOL_01703	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NCIFGHOL_01704	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NCIFGHOL_01705	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NCIFGHOL_01706	1.44e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NCIFGHOL_01707	3.53e-168	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NCIFGHOL_01708	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NCIFGHOL_01709	8.92e-317	-	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_01710	2.21e-143	-	-	-	-	-	-	-	-
NCIFGHOL_01713	6.38e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NCIFGHOL_01714	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NCIFGHOL_01717	3.77e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NCIFGHOL_01718	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NCIFGHOL_01719	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
NCIFGHOL_01723	7.36e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NCIFGHOL_01724	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NCIFGHOL_01725	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NCIFGHOL_01726	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NCIFGHOL_01727	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCIFGHOL_01728	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NCIFGHOL_01729	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCIFGHOL_01730	5.4e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NCIFGHOL_01731	9.76e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NCIFGHOL_01732	2e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NCIFGHOL_01733	1.92e-245	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NCIFGHOL_01734	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCIFGHOL_01735	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NCIFGHOL_01736	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCIFGHOL_01737	2.2e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NCIFGHOL_01738	2.35e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NCIFGHOL_01739	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NCIFGHOL_01740	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NCIFGHOL_01741	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
NCIFGHOL_01742	1.4e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NCIFGHOL_01744	1.61e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
NCIFGHOL_01745	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NCIFGHOL_01746	1.02e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NCIFGHOL_01747	2.07e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
NCIFGHOL_01748	6.33e-232	ampC	-	-	V	-	-	-	Beta-lactamase
NCIFGHOL_01749	1.22e-65	-	-	-	-	-	-	-	-
NCIFGHOL_01750	0.0	-	-	-	M	-	-	-	domain protein
NCIFGHOL_01752	3.87e-76	-	-	-	S	-	-	-	Domain of unknown function DUF1829
NCIFGHOL_01753	1.11e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NCIFGHOL_01754	2.27e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NCIFGHOL_01755	4.01e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NCIFGHOL_01756	3.05e-198	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCIFGHOL_01765	1.11e-30	-	-	-	-	-	-	-	-
NCIFGHOL_01767	2.13e-77	-	-	-	S	-	-	-	VRR_NUC
NCIFGHOL_01769	5.39e-150	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
NCIFGHOL_01770	4.42e-105	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NCIFGHOL_01771	7.5e-43	-	-	-	-	-	-	-	-
NCIFGHOL_01772	1.49e-111	-	-	-	L	-	-	-	AAA domain
NCIFGHOL_01773	1.41e-200	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NCIFGHOL_01774	3.83e-33	-	-	-	S	-	-	-	Siphovirus Gp157
NCIFGHOL_01779	3.22e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NCIFGHOL_01780	2.01e-62	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NCIFGHOL_01781	9.21e-99	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NCIFGHOL_01782	2.74e-26	-	-	-	-	-	-	-	-
NCIFGHOL_01783	1.16e-92	-	-	-	-	-	-	-	-
NCIFGHOL_01785	1.46e-116	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCIFGHOL_01786	2.85e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NCIFGHOL_01787	4.01e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NCIFGHOL_01788	1.61e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NCIFGHOL_01789	2.93e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NCIFGHOL_01790	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NCIFGHOL_01791	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NCIFGHOL_01792	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NCIFGHOL_01793	1.24e-233	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NCIFGHOL_01794	4.33e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NCIFGHOL_01795	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NCIFGHOL_01796	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NCIFGHOL_01797	1.81e-108	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NCIFGHOL_01798	6.39e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NCIFGHOL_01799	1.13e-222	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NCIFGHOL_01800	4.19e-120	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NCIFGHOL_01801	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NCIFGHOL_01802	8.81e-305	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NCIFGHOL_01803	2.15e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NCIFGHOL_01804	1.11e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NCIFGHOL_01805	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NCIFGHOL_01806	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NCIFGHOL_01807	2.57e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01808	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NCIFGHOL_01809	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NCIFGHOL_01810	7.29e-78	isp	-	-	L	-	-	-	Transposase
NCIFGHOL_01811	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
NCIFGHOL_01812	9.77e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NCIFGHOL_01813	1.39e-279	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NCIFGHOL_01814	1.87e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NCIFGHOL_01816	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCIFGHOL_01817	9.82e-235	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NCIFGHOL_01818	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NCIFGHOL_01819	3.45e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NCIFGHOL_01820	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NCIFGHOL_01821	3.61e-156	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCIFGHOL_01822	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NCIFGHOL_01823	8.95e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NCIFGHOL_01825	6.55e-126	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NCIFGHOL_01826	1.78e-208	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NCIFGHOL_01827	2.81e-313	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
NCIFGHOL_01828	1.32e-251	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NCIFGHOL_01829	1.56e-80	-	-	-	-	-	-	-	-
NCIFGHOL_01830	3.37e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_01831	5.18e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NCIFGHOL_01832	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NCIFGHOL_01833	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NCIFGHOL_01834	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NCIFGHOL_01835	1.46e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NCIFGHOL_01836	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NCIFGHOL_01837	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCIFGHOL_01838	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCIFGHOL_01839	6.93e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NCIFGHOL_01840	2.58e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NCIFGHOL_01841	2e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NCIFGHOL_01842	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NCIFGHOL_01843	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NCIFGHOL_01844	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NCIFGHOL_01845	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NCIFGHOL_01846	3.1e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NCIFGHOL_01847	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NCIFGHOL_01848	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NCIFGHOL_01849	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NCIFGHOL_01850	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NCIFGHOL_01851	5.22e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NCIFGHOL_01852	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NCIFGHOL_01853	1.27e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
NCIFGHOL_01854	2.65e-212	-	-	-	S	-	-	-	reductase
NCIFGHOL_01855	0.0	-	-	-	S	-	-	-	amidohydrolase
NCIFGHOL_01856	1.62e-210	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NCIFGHOL_01857	0.0	ilvD	4.2.1.9	-	EG	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
NCIFGHOL_01858	3.45e-52	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NCIFGHOL_01859	1.97e-199	yocS	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
NCIFGHOL_01861	2.67e-154	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NCIFGHOL_01862	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
NCIFGHOL_01863	3.72e-145	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NCIFGHOL_01864	1.02e-20	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NCIFGHOL_01865	7.18e-161	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NCIFGHOL_01866	1.06e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NCIFGHOL_01867	5.17e-250	flp	-	-	V	-	-	-	Beta-lactamase
NCIFGHOL_01868	6.96e-86	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCIFGHOL_01869	4.24e-114	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NCIFGHOL_01870	1.98e-26	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
NCIFGHOL_01871	5.73e-23	-	-	-	-	-	-	-	-
NCIFGHOL_01872	5.72e-154	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NCIFGHOL_01873	9.49e-249	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NCIFGHOL_01878	8.3e-50	-	-	-	H	-	-	-	RibD C-terminal domain
NCIFGHOL_01879	1.06e-81	-	-	-	H	-	-	-	RibD C-terminal domain
NCIFGHOL_01880	3.3e-208	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NCIFGHOL_01881	3.39e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NCIFGHOL_01882	2.4e-296	-	-	-	T	-	-	-	GHKL domain
NCIFGHOL_01883	2.44e-134	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NCIFGHOL_01884	1.96e-167	yneE	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_01885	1.73e-157	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NCIFGHOL_01886	1.4e-282	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NCIFGHOL_01887	4.42e-141	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
NCIFGHOL_01888	2.84e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NCIFGHOL_01889	1.46e-107	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NCIFGHOL_01890	5.81e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NCIFGHOL_01891	1.34e-209	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NCIFGHOL_01892	1.13e-31	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NCIFGHOL_01893	1.88e-147	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NCIFGHOL_01894	3.95e-113	-	-	-	C	-	-	-	Flavodoxin
NCIFGHOL_01895	1.46e-185	lysR	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_01896	1.34e-104	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NCIFGHOL_01897	3.61e-185	-	-	-	S	-	-	-	Alpha beta hydrolase
NCIFGHOL_01898	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NCIFGHOL_01899	2.28e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NCIFGHOL_01900	7.91e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NCIFGHOL_01901	4.14e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NCIFGHOL_01902	1.15e-234	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NCIFGHOL_01903	1.27e-191	-	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_01904	8.12e-205	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NCIFGHOL_01905	5.57e-135	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NCIFGHOL_01906	1.21e-248	-	-	-	S	-	-	-	membrane
NCIFGHOL_01907	3.53e-142	-	-	-	GM	-	-	-	NAD(P)H-binding
NCIFGHOL_01909	6.68e-128	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
NCIFGHOL_01910	1.88e-80	-	-	-	-	-	-	-	-
NCIFGHOL_01911	8.11e-166	-	-	-	F	-	-	-	glutamine amidotransferase
NCIFGHOL_01912	1.47e-255	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
NCIFGHOL_01913	1.28e-151	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NCIFGHOL_01914	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NCIFGHOL_01915	2.47e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NCIFGHOL_01916	1.87e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NCIFGHOL_01917	4.37e-62	ywnA	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_01918	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NCIFGHOL_01919	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
NCIFGHOL_01920	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NCIFGHOL_01921	1.47e-266	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NCIFGHOL_01922	2.14e-296	-	-	-	-	-	-	-	-
NCIFGHOL_01923	1.85e-108	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NCIFGHOL_01924	3.33e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NCIFGHOL_01925	1.25e-65	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NCIFGHOL_01926	1.11e-156	-	-	-	GM	-	-	-	NmrA-like family
NCIFGHOL_01927	3.64e-99	-	-	-	S	ko:K02348	-	ko00000	Gnat family
NCIFGHOL_01928	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
NCIFGHOL_01929	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
NCIFGHOL_01930	5.47e-55	-	-	-	S	-	-	-	Cytochrome B5
NCIFGHOL_01931	7.17e-281	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NCIFGHOL_01932	0.000126	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
NCIFGHOL_01933	2.64e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NCIFGHOL_01934	6.64e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NCIFGHOL_01935	4.9e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
NCIFGHOL_01936	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
NCIFGHOL_01937	7.04e-288	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NCIFGHOL_01939	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NCIFGHOL_01940	1.54e-79	-	-	-	-	-	-	-	-
NCIFGHOL_01941	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NCIFGHOL_01942	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
NCIFGHOL_01943	7.85e-115	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
NCIFGHOL_01944	7.99e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NCIFGHOL_01945	1.49e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01946	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01947	3.38e-50	-	-	-	-	-	-	-	-
NCIFGHOL_01948	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NCIFGHOL_01949	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCIFGHOL_01950	5.37e-221	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NCIFGHOL_01951	2.6e-33	-	-	-	-	-	-	-	-
NCIFGHOL_01952	2.43e-145	-	-	-	-	-	-	-	-
NCIFGHOL_01953	4.47e-276	yttB	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_01954	5.61e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NCIFGHOL_01955	1.48e-114	-	-	-	-	-	-	-	-
NCIFGHOL_01956	3.69e-143	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NCIFGHOL_01957	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NCIFGHOL_01958	5.94e-161	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NCIFGHOL_01960	4.07e-133	-	-	-	-	-	-	-	-
NCIFGHOL_01961	3.27e-276	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NCIFGHOL_01962	8.55e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
NCIFGHOL_01963	8.15e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
NCIFGHOL_01964	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NCIFGHOL_01965	7.2e-56	-	-	-	-	-	-	-	-
NCIFGHOL_01966	1.64e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NCIFGHOL_01967	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NCIFGHOL_01968	8.86e-317	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NCIFGHOL_01969	7.93e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NCIFGHOL_01970	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NCIFGHOL_01971	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NCIFGHOL_01972	2.44e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NCIFGHOL_01973	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NCIFGHOL_01974	3.08e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NCIFGHOL_01975	1.08e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NCIFGHOL_01976	1.94e-44	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NCIFGHOL_01977	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NCIFGHOL_01978	2.55e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
NCIFGHOL_01979	2.29e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_01980	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NCIFGHOL_01981	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NCIFGHOL_01982	3.29e-166	-	-	-	M	-	-	-	PFAM NLP P60 protein
NCIFGHOL_01984	5.45e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
NCIFGHOL_01985	7.44e-183	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
NCIFGHOL_01986	2.55e-111	-	-	-	K	-	-	-	FR47-like protein
NCIFGHOL_01987	1.33e-102	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
NCIFGHOL_01988	5.05e-39	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
NCIFGHOL_01989	5.85e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
NCIFGHOL_01990	6.55e-44	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NCIFGHOL_01991	5.27e-64	-	-	-	-	-	-	-	-
NCIFGHOL_01992	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NCIFGHOL_01993	8.38e-186	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NCIFGHOL_01994	1.21e-136	-	-	-	NU	-	-	-	mannosyl-glycoprotein
NCIFGHOL_01995	9.02e-317	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NCIFGHOL_01996	2.47e-291	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NCIFGHOL_01997	2.62e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
NCIFGHOL_01998	5.53e-97	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NCIFGHOL_01999	1.41e-204	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
NCIFGHOL_02000	3.53e-66	-	-	-	-	-	-	-	-
NCIFGHOL_02001	3.04e-176	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
NCIFGHOL_02003	2.84e-73	-	-	-	-	-	-	-	-
NCIFGHOL_02004	1.87e-148	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NCIFGHOL_02006	8.5e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NCIFGHOL_02007	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NCIFGHOL_02008	1.25e-262	-	-	-	S	-	-	-	associated with various cellular activities
NCIFGHOL_02009	3.78e-307	-	-	-	S	-	-	-	Putative metallopeptidase domain
NCIFGHOL_02010	2.02e-62	-	-	-	-	-	-	-	-
NCIFGHOL_02011	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NCIFGHOL_02012	2.02e-133	-	-	-	K	-	-	-	Helix-turn-helix domain
NCIFGHOL_02013	5.82e-114	ymdB	-	-	S	-	-	-	Macro domain protein
NCIFGHOL_02014	1.04e-252	-	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_02015	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCIFGHOL_02016	1.39e-69	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NCIFGHOL_02017	5.55e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NCIFGHOL_02018	4.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NCIFGHOL_02019	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NCIFGHOL_02020	1.23e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_02021	1.51e-233	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
NCIFGHOL_02022	2.06e-159	XK27_10500	-	-	K	-	-	-	response regulator
NCIFGHOL_02023	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
NCIFGHOL_02024	5.87e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NCIFGHOL_02025	1.93e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCIFGHOL_02026	5.27e-260	-	-	-	-	-	-	-	-
NCIFGHOL_02027	1.76e-68	-	-	-	-	-	-	-	-
NCIFGHOL_02028	1.21e-48	-	-	-	-	-	-	-	-
NCIFGHOL_02029	2.26e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NCIFGHOL_02030	3.84e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NCIFGHOL_02031	8.94e-224	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NCIFGHOL_02032	1.72e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NCIFGHOL_02033	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NCIFGHOL_02034	8.38e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NCIFGHOL_02035	5.26e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NCIFGHOL_02036	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NCIFGHOL_02037	3.15e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
NCIFGHOL_02038	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
NCIFGHOL_02039	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NCIFGHOL_02040	1.29e-54	-	-	-	-	-	-	-	-
NCIFGHOL_02041	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NCIFGHOL_02042	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NCIFGHOL_02043	3.59e-244	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NCIFGHOL_02044	1.5e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
NCIFGHOL_02045	1.15e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NCIFGHOL_02046	5.83e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
NCIFGHOL_02047	1.63e-197	-	-	-	V	-	-	-	(ABC) transporter
NCIFGHOL_02048	6.91e-118	-	-	-	GM	-	-	-	epimerase
NCIFGHOL_02049	5.04e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NCIFGHOL_02050	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_02051	1.28e-171	XK27_07210	-	-	S	-	-	-	B3 4 domain
NCIFGHOL_02052	1e-235	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
NCIFGHOL_02053	1.77e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NCIFGHOL_02054	2.83e-190	-	-	-	-	-	-	-	-
NCIFGHOL_02055	4.38e-164	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NCIFGHOL_02056	2.34e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCIFGHOL_02057	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_02058	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NCIFGHOL_02059	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NCIFGHOL_02060	9.93e-109	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NCIFGHOL_02061	1.23e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NCIFGHOL_02062	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NCIFGHOL_02063	2.48e-309	-	-	-	E	-	-	-	amino acid
NCIFGHOL_02064	9.06e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
NCIFGHOL_02065	8.01e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NCIFGHOL_02066	2.17e-213	-	-	-	GK	-	-	-	ROK family
NCIFGHOL_02067	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NCIFGHOL_02068	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
NCIFGHOL_02069	5.8e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NCIFGHOL_02070	1.71e-81	-	-	-	-	-	-	-	-
NCIFGHOL_02071	3.18e-11	-	-	-	-	-	-	-	-
NCIFGHOL_02072	1.16e-151	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NCIFGHOL_02073	1.86e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NCIFGHOL_02074	9.65e-271	-	-	-	EGP	-	-	-	Major Facilitator
NCIFGHOL_02075	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NCIFGHOL_02076	2.92e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NCIFGHOL_02077	2.85e-206	-	-	-	-	-	-	-	-
NCIFGHOL_02078	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
NCIFGHOL_02079	2.08e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NCIFGHOL_02080	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NCIFGHOL_02081	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NCIFGHOL_02082	7.6e-70	-	-	-	-	-	-	-	-
NCIFGHOL_02083	1.24e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NCIFGHOL_02084	9.04e-317	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCIFGHOL_02085	5.18e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NCIFGHOL_02086	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)