ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GKLCFBDK_00001 9.77e-144 - - - I - - - Acid phosphatase homologues
GKLCFBDK_00002 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GKLCFBDK_00003 1.01e-294 - - - P - - - Chloride transporter, ClC family
GKLCFBDK_00014 2.65e-247 - - - M - - - transferase activity, transferring glycosyl groups
GKLCFBDK_00015 4.37e-266 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
GKLCFBDK_00016 0.0 - - - M - - - transferase activity, transferring glycosyl groups
GKLCFBDK_00017 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
GKLCFBDK_00018 8.18e-211 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
GKLCFBDK_00019 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKLCFBDK_00020 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GKLCFBDK_00021 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GKLCFBDK_00023 0.0 - - - M - - - Pfam:DUF1792
GKLCFBDK_00024 0.0 - - - M - - - family 8
GKLCFBDK_00026 2.6e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GKLCFBDK_00027 3.91e-136 - - - S - - - Protein of unknown function (DUF1461)
GKLCFBDK_00028 2.87e-171 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKLCFBDK_00029 2.28e-121 yutD - - S - - - Protein of unknown function (DUF1027)
GKLCFBDK_00030 2.17e-146 - - - S - - - Calcineurin-like phosphoesterase
GKLCFBDK_00031 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKLCFBDK_00032 4.88e-184 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GKLCFBDK_00034 1.88e-91 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
GKLCFBDK_00035 2.38e-56 - - - - - - - -
GKLCFBDK_00036 2.89e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
GKLCFBDK_00037 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GKLCFBDK_00038 3.69e-234 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GKLCFBDK_00039 1.02e-235 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GKLCFBDK_00040 2.88e-167 yebC - - K - - - Transcriptional regulatory protein
GKLCFBDK_00041 9.88e-180 - - - - - - - -
GKLCFBDK_00042 1.9e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GKLCFBDK_00043 7.6e-270 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GKLCFBDK_00044 1.84e-75 - - - - - - - -
GKLCFBDK_00045 1.54e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKLCFBDK_00046 6.5e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GKLCFBDK_00047 1.1e-195 - - - S - - - haloacid dehalogenase-like hydrolase
GKLCFBDK_00048 6.01e-99 ykuL - - S - - - (CBS) domain
GKLCFBDK_00049 1.41e-121 - - - S ko:K07095 - ko00000 Phosphoesterase
GKLCFBDK_00050 6.73e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKLCFBDK_00051 9.65e-180 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKLCFBDK_00052 1.43e-124 yslB - - S - - - Protein of unknown function (DUF2507)
GKLCFBDK_00053 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GKLCFBDK_00054 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKLCFBDK_00055 7.15e-122 cvpA - - S - - - Colicin V production protein
GKLCFBDK_00056 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
GKLCFBDK_00057 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKLCFBDK_00058 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
GKLCFBDK_00059 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKLCFBDK_00060 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKLCFBDK_00061 6.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GKLCFBDK_00062 1.83e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GKLCFBDK_00063 8.77e-242 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GKLCFBDK_00064 4.74e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKLCFBDK_00065 1.84e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKLCFBDK_00066 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKLCFBDK_00067 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKLCFBDK_00068 9.31e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GKLCFBDK_00069 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKLCFBDK_00070 2.48e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GKLCFBDK_00071 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKLCFBDK_00072 5.91e-197 - - - S - - - Helix-turn-helix domain
GKLCFBDK_00073 9.62e-317 ymfH - - S - - - Peptidase M16
GKLCFBDK_00074 1.23e-293 ymfF - - S - - - Peptidase M16 inactive domain protein
GKLCFBDK_00075 8.15e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GKLCFBDK_00076 2.93e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_00077 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GKLCFBDK_00078 2.8e-119 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
GKLCFBDK_00079 7.72e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GKLCFBDK_00080 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GKLCFBDK_00081 8.48e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
GKLCFBDK_00082 3.53e-311 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GKLCFBDK_00083 1.05e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKLCFBDK_00084 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKLCFBDK_00085 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GKLCFBDK_00086 3.29e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GKLCFBDK_00087 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GKLCFBDK_00088 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKLCFBDK_00089 5.83e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKLCFBDK_00090 4.28e-275 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GKLCFBDK_00091 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKLCFBDK_00092 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKLCFBDK_00093 0.0 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GKLCFBDK_00094 5.35e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKLCFBDK_00095 0.0 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GKLCFBDK_00096 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
GKLCFBDK_00097 8.88e-301 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKLCFBDK_00098 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKLCFBDK_00099 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GKLCFBDK_00100 1.34e-177 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GKLCFBDK_00101 4.16e-180 - - - S - - - Membrane
GKLCFBDK_00102 1.65e-97 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
GKLCFBDK_00103 9.79e-29 - - - - - - - -
GKLCFBDK_00104 2.37e-110 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
GKLCFBDK_00105 1.33e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GKLCFBDK_00106 5.13e-61 - - - - - - - -
GKLCFBDK_00107 1.95e-109 uspA - - T - - - universal stress protein
GKLCFBDK_00108 1.99e-260 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
GKLCFBDK_00109 2.07e-201 yvgN - - S - - - Aldo keto reductase
GKLCFBDK_00110 8.94e-135 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
GKLCFBDK_00111 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
GKLCFBDK_00112 2.23e-177 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GKLCFBDK_00113 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
GKLCFBDK_00114 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKLCFBDK_00115 2.21e-192 - - - K - - - Helix-turn-helix XRE-family like proteins
GKLCFBDK_00116 2.21e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GKLCFBDK_00117 8.55e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
GKLCFBDK_00118 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GKLCFBDK_00119 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
GKLCFBDK_00120 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GKLCFBDK_00121 3.13e-310 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKLCFBDK_00122 5.05e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
GKLCFBDK_00125 1.27e-110 - - - - - - - -
GKLCFBDK_00126 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GKLCFBDK_00127 1.53e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKLCFBDK_00128 2.77e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKLCFBDK_00129 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKLCFBDK_00130 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKLCFBDK_00131 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKLCFBDK_00132 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
GKLCFBDK_00133 1.44e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GKLCFBDK_00134 3.11e-51 yabO - - J - - - S4 domain protein
GKLCFBDK_00135 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKLCFBDK_00136 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKLCFBDK_00137 4.67e-146 - - - S - - - (CBS) domain
GKLCFBDK_00138 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
GKLCFBDK_00139 6.02e-309 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
GKLCFBDK_00140 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
GKLCFBDK_00141 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GKLCFBDK_00142 2.66e-270 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKLCFBDK_00143 1.88e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKLCFBDK_00144 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
GKLCFBDK_00145 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKLCFBDK_00146 2.71e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GKLCFBDK_00147 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKLCFBDK_00148 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKLCFBDK_00149 1.02e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKLCFBDK_00150 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
GKLCFBDK_00151 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKLCFBDK_00152 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKLCFBDK_00153 2.61e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GKLCFBDK_00154 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
GKLCFBDK_00155 6.66e-113 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKLCFBDK_00156 7.48e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
GKLCFBDK_00157 5.32e-208 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GKLCFBDK_00158 1.43e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKLCFBDK_00159 9.19e-193 - - - G - - - Right handed beta helix region
GKLCFBDK_00160 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GKLCFBDK_00161 8.65e-162 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GKLCFBDK_00162 5.56e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKLCFBDK_00163 9.2e-303 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKLCFBDK_00164 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GKLCFBDK_00165 2.25e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKLCFBDK_00166 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKLCFBDK_00167 2.68e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKLCFBDK_00168 6.79e-91 ywiB - - S - - - Domain of unknown function (DUF1934)
GKLCFBDK_00169 2.07e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
GKLCFBDK_00170 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
GKLCFBDK_00171 1.14e-190 yidA - - S - - - hydrolase
GKLCFBDK_00172 1.95e-257 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GKLCFBDK_00173 1.96e-101 - - - - - - - -
GKLCFBDK_00174 1.44e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKLCFBDK_00175 7.77e-315 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKLCFBDK_00176 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GKLCFBDK_00177 8.69e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
GKLCFBDK_00178 1.98e-157 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKLCFBDK_00179 7.03e-216 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKLCFBDK_00180 4.92e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKLCFBDK_00181 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
GKLCFBDK_00182 6.92e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKLCFBDK_00183 1.04e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKLCFBDK_00184 1.3e-200 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GKLCFBDK_00185 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKLCFBDK_00186 7.54e-205 yunF - - F - - - Protein of unknown function DUF72
GKLCFBDK_00188 1.19e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GKLCFBDK_00189 1.33e-228 - - - - - - - -
GKLCFBDK_00190 4.99e-291 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
GKLCFBDK_00191 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GKLCFBDK_00192 1.3e-241 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKLCFBDK_00193 6.41e-236 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
GKLCFBDK_00194 7.04e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
GKLCFBDK_00195 0.0 - - - L - - - DNA helicase
GKLCFBDK_00196 3.16e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GKLCFBDK_00198 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKLCFBDK_00199 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GKLCFBDK_00200 2.83e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKLCFBDK_00201 3.74e-58 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
GKLCFBDK_00202 5.93e-281 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
GKLCFBDK_00203 1.47e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GKLCFBDK_00204 3.24e-56 - - - S - - - Sugar efflux transporter for intercellular exchange
GKLCFBDK_00205 4.84e-199 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GKLCFBDK_00206 2.59e-152 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
GKLCFBDK_00207 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKLCFBDK_00208 1.47e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKLCFBDK_00209 7.14e-138 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKLCFBDK_00210 2.49e-278 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GKLCFBDK_00211 0.0 eriC - - P ko:K03281 - ko00000 chloride
GKLCFBDK_00212 3.14e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GKLCFBDK_00213 1.48e-133 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
GKLCFBDK_00214 6.12e-182 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_00215 1.24e-135 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKLCFBDK_00216 2.41e-205 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
GKLCFBDK_00217 6.68e-98 ywnA - - K - - - Transcriptional regulator
GKLCFBDK_00218 4.69e-200 - - - GM - - - NAD(P)H-binding
GKLCFBDK_00219 4.44e-11 - - - - - - - -
GKLCFBDK_00220 1.86e-287 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
GKLCFBDK_00221 0.0 cadA - - P - - - P-type ATPase
GKLCFBDK_00222 2.76e-163 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GKLCFBDK_00223 9.01e-164 - - - - - - - -
GKLCFBDK_00224 1.85e-69 - - - S - - - Sugar efflux transporter for intercellular exchange
GKLCFBDK_00225 2.22e-312 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
GKLCFBDK_00227 0.0 - - - L - - - Helicase C-terminal domain protein
GKLCFBDK_00228 3.45e-105 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
GKLCFBDK_00229 3.98e-229 ydhF - - S - - - Aldo keto reductase
GKLCFBDK_00230 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GKLCFBDK_00231 1.53e-110 - - - S - - - Membrane
GKLCFBDK_00232 1.08e-183 - - - K - - - helix_turn_helix, arabinose operon control protein
GKLCFBDK_00234 4.13e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKLCFBDK_00235 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GKLCFBDK_00236 2.4e-130 - - - S ko:K07002 - ko00000 Serine hydrolase
GKLCFBDK_00238 9.76e-233 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKLCFBDK_00239 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GKLCFBDK_00240 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
GKLCFBDK_00241 1.63e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
GKLCFBDK_00242 4.54e-49 - - - - - - - -
GKLCFBDK_00243 2.47e-167 - - - IQ - - - dehydrogenase reductase
GKLCFBDK_00244 3.51e-308 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
GKLCFBDK_00245 7.1e-59 ydeP - - K - - - Transcriptional regulator, HxlR family
GKLCFBDK_00257 2.46e-222 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKLCFBDK_00258 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKLCFBDK_00259 3.82e-157 - - - S - - - repeat protein
GKLCFBDK_00260 3.3e-158 pgm6 - - G - - - phosphoglycerate mutase
GKLCFBDK_00261 8.77e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKLCFBDK_00262 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
GKLCFBDK_00263 5.23e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GKLCFBDK_00264 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKLCFBDK_00265 2.59e-25 - - - - - - - -
GKLCFBDK_00266 5.85e-128 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GKLCFBDK_00267 3.3e-43 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GKLCFBDK_00268 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKLCFBDK_00269 3.71e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GKLCFBDK_00270 3.05e-189 ylmH - - S - - - S4 domain protein
GKLCFBDK_00271 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
GKLCFBDK_00272 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKLCFBDK_00273 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKLCFBDK_00274 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKLCFBDK_00275 4.49e-197 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKLCFBDK_00276 2.52e-261 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKLCFBDK_00277 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKLCFBDK_00278 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKLCFBDK_00279 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKLCFBDK_00280 5.99e-74 ftsL - - D - - - Cell division protein FtsL
GKLCFBDK_00281 3.79e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKLCFBDK_00282 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GKLCFBDK_00283 6.9e-77 - - - - - - - -
GKLCFBDK_00284 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
GKLCFBDK_00285 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKLCFBDK_00286 3.75e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKLCFBDK_00287 4.72e-205 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
GKLCFBDK_00288 2.75e-244 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GKLCFBDK_00289 3.54e-27 - - - L ko:K07497 - ko00000 hmm pf00665
GKLCFBDK_00297 2.87e-170 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GKLCFBDK_00298 8.95e-176 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
GKLCFBDK_00299 2.41e-183 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKLCFBDK_00300 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
GKLCFBDK_00301 2.29e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKLCFBDK_00302 5.1e-97 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GKLCFBDK_00303 5.75e-285 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKLCFBDK_00304 6.78e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GKLCFBDK_00305 3.39e-204 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
GKLCFBDK_00306 1.02e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKLCFBDK_00307 3.26e-227 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKLCFBDK_00308 2.75e-100 - - - K - - - Transcriptional regulator, MarR family
GKLCFBDK_00309 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKLCFBDK_00311 8.4e-259 xerS - - L - - - Belongs to the 'phage' integrase family
GKLCFBDK_00312 4.19e-203 rssA - - S - - - Phospholipase, patatin family
GKLCFBDK_00313 1.15e-152 - - - L - - - Integrase
GKLCFBDK_00314 1.33e-196 - - - EG - - - EamA-like transporter family
GKLCFBDK_00315 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
GKLCFBDK_00316 1.16e-127 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
GKLCFBDK_00317 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
GKLCFBDK_00318 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKLCFBDK_00319 8.72e-235 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
GKLCFBDK_00320 1.36e-106 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
GKLCFBDK_00321 1.59e-284 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
GKLCFBDK_00322 1.25e-94 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
GKLCFBDK_00323 6.2e-122 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GKLCFBDK_00324 9.06e-60 - - - - - - - -
GKLCFBDK_00325 1.55e-232 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
GKLCFBDK_00326 5.03e-148 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
GKLCFBDK_00327 2.19e-26 - - - - - - - -
GKLCFBDK_00328 4.25e-222 - - - - - - - -
GKLCFBDK_00329 1.81e-183 - - - H - - - geranyltranstransferase activity
GKLCFBDK_00330 3.7e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
GKLCFBDK_00331 3.75e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
GKLCFBDK_00332 1.09e-82 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
GKLCFBDK_00333 3.46e-99 - - - S - - - Flavodoxin
GKLCFBDK_00334 1.77e-165 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKLCFBDK_00335 1.15e-162 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GKLCFBDK_00336 3.48e-225 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GKLCFBDK_00337 2.69e-228 - - - - - - - -
GKLCFBDK_00338 1.01e-95 - - - - - - - -
GKLCFBDK_00339 7.67e-149 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
GKLCFBDK_00340 0.0 - - - S - - - SEC-C Motif Domain Protein
GKLCFBDK_00341 4.3e-68 - - - - - - - -
GKLCFBDK_00342 3.09e-177 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GKLCFBDK_00343 4.09e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKLCFBDK_00344 2.62e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GKLCFBDK_00346 1.33e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKLCFBDK_00347 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GKLCFBDK_00348 1.91e-185 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
GKLCFBDK_00349 1.4e-283 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GKLCFBDK_00350 2.91e-164 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKLCFBDK_00351 4.44e-292 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GKLCFBDK_00352 5.56e-212 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
GKLCFBDK_00353 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKLCFBDK_00355 1.57e-157 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GKLCFBDK_00356 2.47e-195 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GKLCFBDK_00357 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
GKLCFBDK_00358 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
GKLCFBDK_00359 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_00363 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GKLCFBDK_00364 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKLCFBDK_00365 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKLCFBDK_00366 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKLCFBDK_00367 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKLCFBDK_00368 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKLCFBDK_00369 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKLCFBDK_00370 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GKLCFBDK_00371 9.76e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GKLCFBDK_00372 1.64e-166 yibF - - S - - - overlaps another CDS with the same product name
GKLCFBDK_00373 5.76e-247 yibE - - S - - - overlaps another CDS with the same product name
GKLCFBDK_00374 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKLCFBDK_00375 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKLCFBDK_00376 1.43e-290 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKLCFBDK_00377 6.56e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKLCFBDK_00378 2.55e-215 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKLCFBDK_00379 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKLCFBDK_00380 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GKLCFBDK_00381 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
GKLCFBDK_00382 4.87e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
GKLCFBDK_00383 2.4e-298 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
GKLCFBDK_00384 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GKLCFBDK_00385 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GKLCFBDK_00386 1.03e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GKLCFBDK_00387 1.86e-245 ampC - - V - - - Beta-lactamase
GKLCFBDK_00388 5.26e-67 - - - - - - - -
GKLCFBDK_00389 0.0 - - - M - - - domain protein
GKLCFBDK_00390 6.08e-128 - - - - - - - -
GKLCFBDK_00392 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
GKLCFBDK_00393 1.28e-75 - - - - - - - -
GKLCFBDK_00395 2.3e-115 - - - - - - - -
GKLCFBDK_00396 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GKLCFBDK_00397 8.97e-65 - - - S - - - Cupredoxin-like domain
GKLCFBDK_00398 5.13e-70 - - - S - - - Cupredoxin-like domain
GKLCFBDK_00399 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GKLCFBDK_00400 5.49e-207 - - - EG - - - EamA-like transporter family
GKLCFBDK_00401 7.95e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GKLCFBDK_00402 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKLCFBDK_00403 2.15e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
GKLCFBDK_00404 5.47e-80 yisR1 3.2.1.23 - K ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 helix_turn_helix, arabinose operon control protein
GKLCFBDK_00405 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Glycosyl hydrolases family 31
GKLCFBDK_00406 8.2e-300 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GKLCFBDK_00407 0.0 - 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
GKLCFBDK_00408 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
GKLCFBDK_00409 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
GKLCFBDK_00410 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
GKLCFBDK_00411 6.44e-302 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
GKLCFBDK_00412 1.56e-170 - - - GK - - - ROK family
GKLCFBDK_00413 0.0 - - - G - - - Right handed beta helix region
GKLCFBDK_00414 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
GKLCFBDK_00415 1.27e-222 rhaS2 - - K - - - Transcriptional regulator, AraC family
GKLCFBDK_00416 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKLCFBDK_00418 1.83e-277 xylR - - GK - - - ROK family
GKLCFBDK_00419 2.49e-39 - - - - - - - -
GKLCFBDK_00420 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GKLCFBDK_00421 9.95e-153 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GKLCFBDK_00422 2.71e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GKLCFBDK_00423 0.0 yclK - - T - - - Histidine kinase
GKLCFBDK_00424 5.68e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
GKLCFBDK_00426 2.2e-110 lytE - - M - - - Lysin motif
GKLCFBDK_00427 8.69e-188 - - - S - - - Cof-like hydrolase
GKLCFBDK_00428 3.7e-106 - - - K - - - Transcriptional regulator
GKLCFBDK_00429 0.0 oatA - - I - - - Acyltransferase
GKLCFBDK_00430 1.01e-67 - - - - - - - -
GKLCFBDK_00431 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKLCFBDK_00432 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKLCFBDK_00433 1.11e-164 ybbR - - S - - - YbbR-like protein
GKLCFBDK_00434 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKLCFBDK_00435 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
GKLCFBDK_00436 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GKLCFBDK_00437 1.31e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKLCFBDK_00438 2.76e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GKLCFBDK_00439 6.15e-132 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKLCFBDK_00440 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GKLCFBDK_00441 2.16e-114 - - - K - - - Acetyltransferase (GNAT) domain
GKLCFBDK_00442 1.71e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GKLCFBDK_00443 3.97e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GKLCFBDK_00444 8.77e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKLCFBDK_00445 9.61e-137 - - - - - - - -
GKLCFBDK_00446 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKLCFBDK_00447 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKLCFBDK_00448 3.43e-189 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
GKLCFBDK_00449 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GKLCFBDK_00450 0.0 eriC - - P ko:K03281 - ko00000 chloride
GKLCFBDK_00451 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GKLCFBDK_00452 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKLCFBDK_00453 1.02e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKLCFBDK_00454 7.62e-290 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GKLCFBDK_00455 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKLCFBDK_00457 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKLCFBDK_00458 1.23e-309 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
GKLCFBDK_00459 1.83e-21 - - - - - - - -
GKLCFBDK_00461 3.22e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GKLCFBDK_00462 6.97e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GKLCFBDK_00463 9.4e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GKLCFBDK_00464 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
GKLCFBDK_00465 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKLCFBDK_00466 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKLCFBDK_00467 2.12e-19 - - - - - - - -
GKLCFBDK_00468 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GKLCFBDK_00469 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GKLCFBDK_00470 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
GKLCFBDK_00471 1.91e-204 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
GKLCFBDK_00472 1.06e-258 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GKLCFBDK_00473 1.95e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKLCFBDK_00474 1.07e-203 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
GKLCFBDK_00475 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
GKLCFBDK_00476 4.31e-176 lutC - - S ko:K00782 - ko00000 LUD domain
GKLCFBDK_00477 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKLCFBDK_00478 8.07e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GKLCFBDK_00479 1.03e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKLCFBDK_00480 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKLCFBDK_00481 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
GKLCFBDK_00482 2.11e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GKLCFBDK_00483 1.58e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKLCFBDK_00484 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKLCFBDK_00485 1.13e-120 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKLCFBDK_00486 7.35e-150 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GKLCFBDK_00487 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GKLCFBDK_00488 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00489 4.88e-300 - - - L - - - Transposase
GKLCFBDK_00490 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_00491 1.26e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
GKLCFBDK_00492 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKLCFBDK_00493 3.58e-237 - - - - - - - -
GKLCFBDK_00494 9.99e-83 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKLCFBDK_00495 4.05e-266 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
GKLCFBDK_00496 2.52e-206 - - - K - - - LysR substrate binding domain
GKLCFBDK_00497 1.61e-184 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKLCFBDK_00498 9.45e-126 - - - K - - - acetyltransferase
GKLCFBDK_00499 3.04e-234 - - - - - - - -
GKLCFBDK_00501 1.86e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GKLCFBDK_00502 1.03e-127 - - - S - - - AmiS/UreI family transporter
GKLCFBDK_00503 8.76e-63 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
GKLCFBDK_00504 1.15e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
GKLCFBDK_00505 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
GKLCFBDK_00506 3.08e-102 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GKLCFBDK_00507 1.69e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GKLCFBDK_00508 1.4e-145 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GKLCFBDK_00509 3.9e-208 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GKLCFBDK_00510 2e-56 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKLCFBDK_00511 1.46e-96 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKLCFBDK_00512 2.14e-234 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
GKLCFBDK_00513 9.97e-185 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GKLCFBDK_00514 3.28e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKLCFBDK_00515 1.69e-169 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
GKLCFBDK_00516 2.33e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKLCFBDK_00517 9.65e-196 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GKLCFBDK_00518 2.58e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GKLCFBDK_00519 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKLCFBDK_00520 3.02e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GKLCFBDK_00521 2.69e-196 - - - - - - - -
GKLCFBDK_00522 2.89e-309 - - - M - - - Glycosyl transferase
GKLCFBDK_00523 9.4e-280 - - - G - - - Glycosyl hydrolases family 8
GKLCFBDK_00524 1.05e-176 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GKLCFBDK_00525 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GKLCFBDK_00526 4.77e-305 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
GKLCFBDK_00527 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
GKLCFBDK_00528 4.22e-111 - - - Q - - - Methyltransferase
GKLCFBDK_00529 1.46e-59 - - - K - - - Cro/C1-type HTH DNA-binding domain
GKLCFBDK_00532 5.66e-295 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GKLCFBDK_00533 2.69e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GKLCFBDK_00534 5.35e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GKLCFBDK_00535 1.76e-122 - - - S - - - NADPH-dependent FMN reductase
GKLCFBDK_00536 2.04e-230 - - - S - - - Conserved hypothetical protein 698
GKLCFBDK_00537 3.17e-175 - - - I - - - alpha/beta hydrolase fold
GKLCFBDK_00538 4.16e-216 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GKLCFBDK_00539 6.1e-227 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
GKLCFBDK_00540 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
GKLCFBDK_00541 0.0 arcT - - E - - - Dipeptidase
GKLCFBDK_00542 1.81e-274 - - - EGP - - - Transporter, major facilitator family protein
GKLCFBDK_00543 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
GKLCFBDK_00544 1.37e-178 - - - V - - - Beta-lactamase enzyme family
GKLCFBDK_00545 4.68e-281 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKLCFBDK_00546 7.62e-97 - - - - - - - -
GKLCFBDK_00547 5.22e-255 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GKLCFBDK_00548 6.92e-31 - - - - - - - -
GKLCFBDK_00551 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
GKLCFBDK_00552 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
GKLCFBDK_00553 4.7e-264 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
GKLCFBDK_00554 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00555 4.88e-300 - - - L - - - Transposase
GKLCFBDK_00556 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_00557 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_00559 5.67e-198 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKLCFBDK_00560 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKLCFBDK_00561 1.1e-161 - - - O - - - Zinc-dependent metalloprotease
GKLCFBDK_00562 3.08e-147 - - - S - - - Membrane
GKLCFBDK_00563 3.39e-254 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GKLCFBDK_00564 8.83e-112 - - - S - - - Domain of unknown function (DUF4767)
GKLCFBDK_00565 3.7e-19 - - - - - - - -
GKLCFBDK_00566 4.39e-267 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
GKLCFBDK_00567 4.02e-121 - - - K - - - PFAM GCN5-related N-acetyltransferase
GKLCFBDK_00568 2.82e-105 - - - - - - - -
GKLCFBDK_00569 8.4e-162 - - - M - - - Lysin motif
GKLCFBDK_00570 2.73e-248 - - - EGP - - - Major Facilitator
GKLCFBDK_00571 3.36e-278 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKLCFBDK_00572 1.06e-249 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GKLCFBDK_00573 3.53e-297 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
GKLCFBDK_00574 0.0 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
GKLCFBDK_00575 4.36e-127 ywlG - - S - - - Belongs to the UPF0340 family
GKLCFBDK_00576 7.91e-120 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GKLCFBDK_00577 2.89e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKLCFBDK_00578 2.93e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GKLCFBDK_00579 2.11e-165 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
GKLCFBDK_00580 2.68e-129 - - - K - - - Cyclic nucleotide-binding domain
GKLCFBDK_00581 3.87e-164 - - - S - - - PFAM Archaeal ATPase
GKLCFBDK_00582 4.9e-205 - - - J - - - Methyltransferase
GKLCFBDK_00583 7.84e-284 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
GKLCFBDK_00584 5.89e-104 - - - L - - - Belongs to the 'phage' integrase family
GKLCFBDK_00587 1.45e-72 - - - L - - - Resolvase, N terminal domain
GKLCFBDK_00588 4.88e-300 - - - L - - - Transposase
GKLCFBDK_00589 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKLCFBDK_00590 1.46e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKLCFBDK_00591 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GKLCFBDK_00592 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKLCFBDK_00593 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKLCFBDK_00594 2.95e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKLCFBDK_00595 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GKLCFBDK_00596 2.11e-161 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
GKLCFBDK_00597 3.45e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKLCFBDK_00598 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKLCFBDK_00599 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GKLCFBDK_00600 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKLCFBDK_00601 8.5e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKLCFBDK_00602 2.28e-172 jag - - S ko:K06346 - ko00000 R3H domain protein
GKLCFBDK_00603 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKLCFBDK_00604 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKLCFBDK_00605 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKLCFBDK_00606 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKLCFBDK_00607 3.61e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GKLCFBDK_00608 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKLCFBDK_00609 7.3e-113 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
GKLCFBDK_00610 1.58e-204 - - - S - - - reductase
GKLCFBDK_00612 1.36e-52 - - - M - - - Glycosyl transferases group 1
GKLCFBDK_00613 8.65e-59 - - - M - - - Glycosyl transferases group 1
GKLCFBDK_00614 3.48e-212 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GKLCFBDK_00615 1.51e-182 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKLCFBDK_00616 4.95e-160 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKLCFBDK_00617 0.0 - - - S - - - amidohydrolase
GKLCFBDK_00618 0.0 - - - K - - - Aminotransferase class I and II
GKLCFBDK_00619 6.55e-155 azlC - - E - - - azaleucine resistance protein AzlC
GKLCFBDK_00620 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
GKLCFBDK_00621 4.17e-156 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GKLCFBDK_00622 3.05e-44 - - - - - - - -
GKLCFBDK_00624 8.04e-191 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
GKLCFBDK_00625 2.15e-113 - - - K - - - Bacterial regulatory proteins, tetR family
GKLCFBDK_00626 2.75e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GKLCFBDK_00627 3.37e-162 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GKLCFBDK_00628 2.07e-148 - - - S - - - GyrI-like small molecule binding domain
GKLCFBDK_00629 1.69e-159 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GKLCFBDK_00630 2.6e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKLCFBDK_00631 4.26e-249 flp - - V - - - Beta-lactamase
GKLCFBDK_00632 1.34e-72 - - - S - - - Antibiotic biosynthesis monooxygenase
GKLCFBDK_00633 2.99e-114 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GKLCFBDK_00634 4.19e-154 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKLCFBDK_00635 3.44e-282 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKLCFBDK_00639 2.48e-152 - - - H - - - RibD C-terminal domain
GKLCFBDK_00640 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00641 1.88e-219 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKLCFBDK_00642 1.52e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKLCFBDK_00643 1.29e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GKLCFBDK_00644 1.4e-147 yjbH - - Q - - - Thioredoxin
GKLCFBDK_00645 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKLCFBDK_00646 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00651 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GKLCFBDK_00652 1.15e-196 - - - S - - - Calcineurin-like phosphoesterase
GKLCFBDK_00655 1.38e-139 - - - - - - - -
GKLCFBDK_00656 2.68e-316 - - - EGP - - - Major Facilitator
GKLCFBDK_00657 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
GKLCFBDK_00658 2.04e-167 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GKLCFBDK_00659 5.03e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
GKLCFBDK_00660 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKLCFBDK_00661 4.16e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKLCFBDK_00662 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
GKLCFBDK_00663 2.25e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GKLCFBDK_00665 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
GKLCFBDK_00666 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GKLCFBDK_00667 1.1e-136 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GKLCFBDK_00668 3.59e-81 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GKLCFBDK_00669 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GKLCFBDK_00670 3.87e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GKLCFBDK_00671 0.0 - - - S - - - Bacterial membrane protein, YfhO
GKLCFBDK_00672 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKLCFBDK_00673 1.27e-215 - - - I - - - alpha/beta hydrolase fold
GKLCFBDK_00674 2.58e-275 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKLCFBDK_00675 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKLCFBDK_00676 5.84e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_00677 1.67e-178 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GKLCFBDK_00678 1.02e-77 gmT1 - - EG - - - EamA-like transporter family
GKLCFBDK_00679 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GKLCFBDK_00680 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKLCFBDK_00681 6.72e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
GKLCFBDK_00682 4.86e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GKLCFBDK_00683 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKLCFBDK_00684 5.12e-266 yacL - - S - - - domain protein
GKLCFBDK_00685 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKLCFBDK_00686 2.16e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKLCFBDK_00687 1.82e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKLCFBDK_00688 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKLCFBDK_00689 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKLCFBDK_00690 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GKLCFBDK_00691 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKLCFBDK_00692 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKLCFBDK_00693 5.57e-290 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
GKLCFBDK_00695 8.02e-313 - - - M - - - Glycosyl transferase family group 2
GKLCFBDK_00696 1.26e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKLCFBDK_00697 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKLCFBDK_00698 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKLCFBDK_00699 2.39e-64 - - - - - - - -
GKLCFBDK_00701 1.2e-64 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKLCFBDK_00702 1.61e-74 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
GKLCFBDK_00703 1.36e-120 - - - S - - - Protein of unknown function (DUF1700)
GKLCFBDK_00704 7.63e-169 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GKLCFBDK_00705 1.11e-283 - - - L ko:K07487 - ko00000 Transposase
GKLCFBDK_00706 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GKLCFBDK_00707 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKLCFBDK_00708 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKLCFBDK_00709 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
GKLCFBDK_00710 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKLCFBDK_00711 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKLCFBDK_00712 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKLCFBDK_00713 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKLCFBDK_00714 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
GKLCFBDK_00715 3.17e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKLCFBDK_00716 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
GKLCFBDK_00717 1.29e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKLCFBDK_00718 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
GKLCFBDK_00719 4.69e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKLCFBDK_00720 2.58e-177 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GKLCFBDK_00721 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GKLCFBDK_00722 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GKLCFBDK_00723 5.83e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
GKLCFBDK_00724 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GKLCFBDK_00725 3.12e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GKLCFBDK_00726 2.48e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GKLCFBDK_00727 4.1e-251 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKLCFBDK_00728 4.4e-171 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKLCFBDK_00729 6.03e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKLCFBDK_00730 1.8e-177 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKLCFBDK_00731 2.69e-183 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
GKLCFBDK_00732 3.46e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKLCFBDK_00733 8.05e-231 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKLCFBDK_00734 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GKLCFBDK_00735 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKLCFBDK_00736 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKLCFBDK_00737 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKLCFBDK_00738 3.23e-108 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GKLCFBDK_00739 0.0 - - - E - - - amino acid
GKLCFBDK_00740 0.0 ydaO - - E - - - amino acid
GKLCFBDK_00741 2.63e-53 - - - - - - - -
GKLCFBDK_00742 2.16e-89 - - - K - - - Transcriptional regulator
GKLCFBDK_00743 6.72e-303 - - - EGP - - - Major Facilitator
GKLCFBDK_00744 4.87e-47 - - - C - - - Nitroreductase family
GKLCFBDK_00745 9.26e-33 - - - K - - - HxlR-like helix-turn-helix
GKLCFBDK_00746 3.54e-140 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GKLCFBDK_00747 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00748 2.51e-283 - - - L ko:K07487 - ko00000 Transposase
GKLCFBDK_00754 1.71e-52 - - - S - - - Protein of unknown function (DUF4065)
GKLCFBDK_00756 9.96e-52 - - - V - - - Abi-like protein
GKLCFBDK_00757 4.85e-50 - - - D - - - nuclear chromosome segregation
GKLCFBDK_00758 2.65e-07 - - - K - - - Helix-turn-helix domain
GKLCFBDK_00760 2.89e-58 ydeP - - K - - - Transcriptional regulator, HxlR family
GKLCFBDK_00761 6.88e-144 - - - K - - - Transcriptional regulator, TetR family
GKLCFBDK_00763 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKLCFBDK_00764 8.91e-122 - - - - - - - -
GKLCFBDK_00765 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKLCFBDK_00766 1.2e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKLCFBDK_00767 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GKLCFBDK_00768 9.24e-114 - - - S - - - ECF-type riboflavin transporter, S component
GKLCFBDK_00769 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GKLCFBDK_00770 1.48e-214 - - - C - - - Aldo keto reductase
GKLCFBDK_00771 3.7e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GKLCFBDK_00772 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GKLCFBDK_00773 6.98e-266 - - - P - - - Voltage gated chloride channel
GKLCFBDK_00774 3.77e-288 sptS - - T - - - Histidine kinase
GKLCFBDK_00775 8.32e-149 dltr - - K - - - response regulator
GKLCFBDK_00776 1.24e-112 - - - T - - - Region found in RelA / SpoT proteins
GKLCFBDK_00777 2.26e-89 - - - - - - - -
GKLCFBDK_00778 1.76e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GKLCFBDK_00779 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GKLCFBDK_00780 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GKLCFBDK_00781 3.74e-265 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKLCFBDK_00782 2.2e-223 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
GKLCFBDK_00783 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GKLCFBDK_00784 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GKLCFBDK_00785 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKLCFBDK_00786 5.56e-136 - - - K - - - PFAM GCN5-related N-acetyltransferase
GKLCFBDK_00788 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
GKLCFBDK_00789 8.68e-44 - - - - - - - -
GKLCFBDK_00790 2.49e-276 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKLCFBDK_00791 1.48e-222 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKLCFBDK_00792 2.79e-97 - - - O - - - OsmC-like protein
GKLCFBDK_00795 2.23e-137 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKLCFBDK_00796 3.81e-190 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKLCFBDK_00799 0.0 - - - S - - - Putative peptidoglycan binding domain
GKLCFBDK_00800 2.24e-66 - - - - - - - -
GKLCFBDK_00801 1.53e-269 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
GKLCFBDK_00802 2.4e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GKLCFBDK_00803 3.52e-201 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKLCFBDK_00804 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKLCFBDK_00805 1.75e-188 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKLCFBDK_00806 5.08e-191 - - - E - - - Glyoxalase-like domain
GKLCFBDK_00807 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GKLCFBDK_00808 8.85e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
GKLCFBDK_00809 9.06e-125 - - - S - - - reductase
GKLCFBDK_00811 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKLCFBDK_00812 9.36e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GKLCFBDK_00813 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
GKLCFBDK_00814 7.05e-289 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GKLCFBDK_00815 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GKLCFBDK_00816 5.03e-193 yycI - - S - - - YycH protein
GKLCFBDK_00817 0.0 yycH - - S - - - YycH protein
GKLCFBDK_00818 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKLCFBDK_00819 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GKLCFBDK_00821 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GKLCFBDK_00822 2.2e-95 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
GKLCFBDK_00824 3.18e-157 - - - S - - - Fic/DOC family
GKLCFBDK_00825 2.17e-209 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
GKLCFBDK_00826 7.71e-81 - - - - - - - -
GKLCFBDK_00827 7.93e-271 yttB - - EGP - - - Major Facilitator
GKLCFBDK_00828 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GKLCFBDK_00829 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GKLCFBDK_00830 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GKLCFBDK_00831 4.88e-300 - - - L - - - Transposase
GKLCFBDK_00832 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKLCFBDK_00833 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKLCFBDK_00834 3.75e-246 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
GKLCFBDK_00835 3.68e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
GKLCFBDK_00836 2.32e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
GKLCFBDK_00837 1.73e-308 yhdP - - S - - - Transporter associated domain
GKLCFBDK_00838 8.76e-202 - - - V - - - (ABC) transporter
GKLCFBDK_00839 1.15e-116 - - - GM - - - epimerase
GKLCFBDK_00840 8.71e-117 - - - K - - - Domain of unknown function (DUF1836)
GKLCFBDK_00841 3.33e-102 yybA - - K - - - Transcriptional regulator
GKLCFBDK_00842 7.74e-173 XK27_07210 - - S - - - B3 4 domain
GKLCFBDK_00843 2.7e-241 XK27_12525 - - S - - - AI-2E family transporter
GKLCFBDK_00844 7.79e-197 - - - G - - - Xylose isomerase domain protein TIM barrel
GKLCFBDK_00845 1.22e-206 - - - - - - - -
GKLCFBDK_00846 2.41e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKLCFBDK_00847 2.34e-241 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKLCFBDK_00848 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_00849 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKLCFBDK_00850 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKLCFBDK_00851 5.75e-114 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKLCFBDK_00852 2.22e-173 gntR - - K - - - UbiC transcription regulator-associated domain protein
GKLCFBDK_00853 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GKLCFBDK_00854 2.13e-310 - - - E - - - amino acid
GKLCFBDK_00855 6.38e-180 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GKLCFBDK_00856 4.72e-303 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKLCFBDK_00857 8.19e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
GKLCFBDK_00858 1.45e-312 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKLCFBDK_00859 3.76e-214 - - - GK - - - ROK family
GKLCFBDK_00860 0.0 fusA1 - - J - - - elongation factor G
GKLCFBDK_00861 7.46e-106 uspA3 - - T - - - universal stress protein
GKLCFBDK_00862 1.17e-247 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GKLCFBDK_00863 1.78e-83 - - - - - - - -
GKLCFBDK_00864 3.18e-11 - - - - - - - -
GKLCFBDK_00865 7.02e-34 - - - K - - - ArsR family transcriptional regulator
GKLCFBDK_00866 1.11e-158 - - - I - - - Serine aminopeptidase, S33
GKLCFBDK_00867 9.53e-151 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GKLCFBDK_00868 1.25e-172 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKLCFBDK_00869 9.65e-271 - - - EGP - - - Major Facilitator
GKLCFBDK_00870 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
GKLCFBDK_00871 8.6e-225 - - - C - - - Zinc-binding dehydrogenase
GKLCFBDK_00872 2.85e-206 - - - - - - - -
GKLCFBDK_00873 1.3e-95 - - - K - - - Transcriptional regulator
GKLCFBDK_00874 1.78e-241 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKLCFBDK_00875 3.68e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GKLCFBDK_00876 1.98e-299 - - - L - - - transposase IS116 IS110 IS902 family protein
GKLCFBDK_00877 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
GKLCFBDK_00878 6.5e-71 - - - - - - - -
GKLCFBDK_00879 2.29e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GKLCFBDK_00880 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_00881 1.81e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GKLCFBDK_00882 8.5e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
GKLCFBDK_00883 7.72e-178 - - - IQ - - - KR domain
GKLCFBDK_00884 6.65e-234 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
GKLCFBDK_00885 1.39e-232 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GKLCFBDK_00886 6.13e-174 - - - S - - - Double zinc ribbon
GKLCFBDK_00887 1.25e-249 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKLCFBDK_00888 4.37e-168 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKLCFBDK_00889 2.2e-271 - - - - - - - -
GKLCFBDK_00892 3.07e-190 - - - S - - - PD-(D/E)XK nuclease family transposase
GKLCFBDK_00893 1.9e-147 - - - S - - - PD-(D/E)XK nuclease family transposase
GKLCFBDK_00894 2.14e-148 - - - S - - - HAD hydrolase, family IA, variant
GKLCFBDK_00895 0.0 yagE - - E - - - amino acid
GKLCFBDK_00896 2.93e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GKLCFBDK_00897 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKLCFBDK_00898 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GKLCFBDK_00899 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKLCFBDK_00900 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKLCFBDK_00901 1.01e-186 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKLCFBDK_00902 5.39e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKLCFBDK_00903 5.98e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKLCFBDK_00904 5.88e-295 - - - - - - - -
GKLCFBDK_00905 1.07e-299 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GKLCFBDK_00906 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GKLCFBDK_00907 1.78e-97 - - - F - - - Nudix hydrolase
GKLCFBDK_00908 4.1e-134 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
GKLCFBDK_00909 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GKLCFBDK_00910 4.44e-36 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
GKLCFBDK_00911 1.14e-193 - - - - - - - -
GKLCFBDK_00912 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
GKLCFBDK_00913 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
GKLCFBDK_00914 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
GKLCFBDK_00915 3.27e-230 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKLCFBDK_00916 6.47e-10 - - - S - - - CsbD-like
GKLCFBDK_00917 1.98e-42 - - - S - - - Transglycosylase associated protein
GKLCFBDK_00918 6.05e-290 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKLCFBDK_00919 3.87e-161 pgm3 - - G - - - phosphoglycerate mutase
GKLCFBDK_00920 2.31e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
GKLCFBDK_00921 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKLCFBDK_00922 5.43e-311 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GKLCFBDK_00923 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
GKLCFBDK_00924 6.71e-207 - - - EG - - - EamA-like transporter family
GKLCFBDK_00925 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKLCFBDK_00926 2.48e-40 - - - L - - - Transposase DDE domain
GKLCFBDK_00927 7.22e-167 - - - L - - - Transposase DDE domain
GKLCFBDK_00928 9.01e-284 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKLCFBDK_00929 3.88e-59 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GKLCFBDK_00931 2.79e-32 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKLCFBDK_00932 4.41e-52 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKLCFBDK_00937 2.04e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GKLCFBDK_00938 4.35e-282 - - - S ko:K07133 - ko00000 cog cog1373
GKLCFBDK_00940 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GKLCFBDK_00942 3.16e-229 - - - - - - - -
GKLCFBDK_00943 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00944 2.22e-206 - - - S ko:K07088 - ko00000 Membrane transport protein
GKLCFBDK_00945 1.18e-155 - - - T - - - Transcriptional regulatory protein, C terminal
GKLCFBDK_00946 1.75e-294 - - - T - - - GHKL domain
GKLCFBDK_00947 2e-117 - - - S - - - Peptidase propeptide and YPEB domain
GKLCFBDK_00948 3.66e-167 yneE - - K - - - Transcriptional regulator
GKLCFBDK_00949 1.04e-158 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
GKLCFBDK_00950 1.99e-282 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
GKLCFBDK_00951 1.62e-143 - - - M - - - Protein of unknown function (DUF3737)
GKLCFBDK_00952 2e-73 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
GKLCFBDK_00953 1.12e-210 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
GKLCFBDK_00954 1.32e-111 - - - C - - - Flavodoxin
GKLCFBDK_00955 8.7e-28 - - - - - - - -
GKLCFBDK_00956 2.21e-196 lysR - - K - - - Transcriptional regulator
GKLCFBDK_00957 6.09e-113 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GKLCFBDK_00958 1.74e-151 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GKLCFBDK_00959 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00960 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00961 1.19e-259 coiA - - S ko:K06198 - ko00000 Competence protein
GKLCFBDK_00962 5.67e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKLCFBDK_00963 8.23e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKLCFBDK_00964 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
GKLCFBDK_00966 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_00970 9.06e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
GKLCFBDK_00971 9.75e-101 - - - K - - - Peptidase S24-like
GKLCFBDK_00974 3.5e-25 - - - S - - - Protein of unknown function (DUF4231)
GKLCFBDK_00975 6.43e-89 - - - S - - - MTH538 TIR-like domain (DUF1863)
GKLCFBDK_00976 3.87e-33 - - - - - - - -
GKLCFBDK_00977 2.16e-286 int7 - - L - - - Belongs to the 'phage' integrase family
GKLCFBDK_00978 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKLCFBDK_00979 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKLCFBDK_00980 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GKLCFBDK_00981 5.7e-118 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKLCFBDK_00982 1.13e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKLCFBDK_00983 1.04e-83 - - - - - - - -
GKLCFBDK_00984 4.45e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GKLCFBDK_00985 7.03e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKLCFBDK_00986 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKLCFBDK_00987 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKLCFBDK_00988 1.96e-65 ylxQ - - J - - - ribosomal protein
GKLCFBDK_00989 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GKLCFBDK_00990 2.39e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GKLCFBDK_00991 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GKLCFBDK_00992 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKLCFBDK_00993 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKLCFBDK_00994 8.1e-299 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GKLCFBDK_00995 2.03e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GKLCFBDK_00996 1.5e-181 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKLCFBDK_00997 1.27e-292 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKLCFBDK_00998 8.54e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKLCFBDK_00999 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GKLCFBDK_01000 4.47e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKLCFBDK_01001 1.01e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GKLCFBDK_01002 6.88e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKLCFBDK_01003 3.94e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
GKLCFBDK_01004 1.14e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GKLCFBDK_01005 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GKLCFBDK_01006 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GKLCFBDK_01007 2.7e-47 ynzC - - S - - - UPF0291 protein
GKLCFBDK_01008 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKLCFBDK_01009 5.56e-268 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GKLCFBDK_01010 8.42e-163 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKLCFBDK_01012 8.13e-22 - - - - - - - -
GKLCFBDK_01013 1.69e-25 - - - S - - - Phage gp6-like head-tail connector protein
GKLCFBDK_01014 9.02e-237 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
GKLCFBDK_01015 2.44e-180 - - - S - - - Phage portal protein
GKLCFBDK_01016 6.53e-254 terL - - S - - - overlaps another CDS with the same product name
GKLCFBDK_01017 2.33e-28 terS - - L - - - Phage terminase, small subunit
GKLCFBDK_01018 8.12e-31 - - - L - - - HNH endonuclease
GKLCFBDK_01021 1.69e-109 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
GKLCFBDK_01022 4.5e-53 - - - L - - - Primase C terminal 1 (PriCT-1)
GKLCFBDK_01030 0.000121 - - - L - - - GIY-YIG catalytic domain
GKLCFBDK_01031 6.03e-66 - - - L - - - Belongs to the 'phage' integrase family
GKLCFBDK_01032 1.53e-122 - - - - - - - -
GKLCFBDK_01033 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKLCFBDK_01034 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GKLCFBDK_01035 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKLCFBDK_01036 6.85e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKLCFBDK_01037 2.09e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKLCFBDK_01038 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKLCFBDK_01039 2.44e-20 - - - - - - - -
GKLCFBDK_01040 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
GKLCFBDK_01041 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GKLCFBDK_01042 5.06e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKLCFBDK_01043 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKLCFBDK_01044 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKLCFBDK_01045 2.52e-208 - - - S - - - Tetratricopeptide repeat
GKLCFBDK_01046 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKLCFBDK_01047 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKLCFBDK_01048 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GKLCFBDK_01049 1.95e-201 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GKLCFBDK_01050 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GKLCFBDK_01051 1.43e-115 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GKLCFBDK_01052 2.79e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GKLCFBDK_01053 5.2e-253 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GKLCFBDK_01054 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKLCFBDK_01055 6.8e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GKLCFBDK_01056 2.6e-59 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GKLCFBDK_01057 5.31e-284 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKLCFBDK_01058 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GKLCFBDK_01059 2.37e-175 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
GKLCFBDK_01060 2.02e-62 yktA - - S - - - Belongs to the UPF0223 family
GKLCFBDK_01061 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
GKLCFBDK_01062 1.06e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKLCFBDK_01063 3.28e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
GKLCFBDK_01064 4.05e-266 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
GKLCFBDK_01065 1.68e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKLCFBDK_01066 2.79e-107 - - - - - - - -
GKLCFBDK_01067 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
GKLCFBDK_01068 2.71e-235 - - - I - - - Diacylglycerol kinase catalytic
GKLCFBDK_01069 4.37e-39 - - - - - - - -
GKLCFBDK_01070 4.5e-241 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GKLCFBDK_01072 2.15e-75 - - - - - - - -
GKLCFBDK_01073 2.42e-261 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GKLCFBDK_01074 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKLCFBDK_01075 2.06e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKLCFBDK_01076 3.67e-180 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKLCFBDK_01077 3.25e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKLCFBDK_01078 7.77e-282 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKLCFBDK_01079 6.24e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKLCFBDK_01080 4.77e-316 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKLCFBDK_01081 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKLCFBDK_01082 1.92e-220 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKLCFBDK_01083 2.82e-63 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_01084 3.24e-77 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_01085 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01086 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GKLCFBDK_01087 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKLCFBDK_01088 1.23e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKLCFBDK_01089 3.51e-182 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKLCFBDK_01090 3.54e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKLCFBDK_01091 1.43e-185 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKLCFBDK_01092 1.34e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GKLCFBDK_01093 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKLCFBDK_01094 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKLCFBDK_01095 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKLCFBDK_01096 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GKLCFBDK_01097 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKLCFBDK_01098 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKLCFBDK_01099 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKLCFBDK_01100 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GKLCFBDK_01101 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GKLCFBDK_01102 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKLCFBDK_01103 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKLCFBDK_01104 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKLCFBDK_01105 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKLCFBDK_01106 3.02e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKLCFBDK_01107 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKLCFBDK_01108 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKLCFBDK_01109 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKLCFBDK_01110 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GKLCFBDK_01111 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKLCFBDK_01112 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKLCFBDK_01113 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKLCFBDK_01114 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKLCFBDK_01115 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKLCFBDK_01116 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKLCFBDK_01117 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GKLCFBDK_01118 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKLCFBDK_01119 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GKLCFBDK_01120 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKLCFBDK_01121 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKLCFBDK_01122 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKLCFBDK_01123 4.63e-152 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GKLCFBDK_01124 2.43e-265 - - - - - - - -
GKLCFBDK_01125 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKLCFBDK_01126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKLCFBDK_01127 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
GKLCFBDK_01128 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKLCFBDK_01129 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GKLCFBDK_01130 5.17e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GKLCFBDK_01131 1.69e-231 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
GKLCFBDK_01132 4.07e-13 - - - - - - - -
GKLCFBDK_01138 1.29e-148 dgk2 - - F - - - deoxynucleoside kinase
GKLCFBDK_01139 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
GKLCFBDK_01140 2.35e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKLCFBDK_01141 6.58e-152 - - - I - - - phosphatase
GKLCFBDK_01142 1.06e-106 - - - S - - - Threonine/Serine exporter, ThrE
GKLCFBDK_01143 2.44e-165 - - - S - - - Putative threonine/serine exporter
GKLCFBDK_01144 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
GKLCFBDK_01145 1.34e-160 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
GKLCFBDK_01146 2.85e-212 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GKLCFBDK_01147 1.27e-152 - - - S - - - membrane
GKLCFBDK_01148 5.5e-141 - - - S - - - VIT family
GKLCFBDK_01149 2.79e-107 - - - T - - - Belongs to the universal stress protein A family
GKLCFBDK_01150 1.14e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01151 1.34e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKLCFBDK_01152 7.44e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKLCFBDK_01153 2.11e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKLCFBDK_01154 3.85e-280 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKLCFBDK_01155 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKLCFBDK_01156 1.58e-72 - - - - - - - -
GKLCFBDK_01157 1.26e-96 - - - K - - - MerR HTH family regulatory protein
GKLCFBDK_01158 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GKLCFBDK_01159 2.33e-154 - - - S - - - Domain of unknown function (DUF4811)
GKLCFBDK_01160 5.1e-207 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKLCFBDK_01162 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKLCFBDK_01163 3.74e-120 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GKLCFBDK_01164 4.54e-240 - - - I - - - Alpha beta
GKLCFBDK_01165 0.0 qacA - - EGP - - - Major Facilitator
GKLCFBDK_01166 1.34e-152 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GKLCFBDK_01167 0.0 - - - S - - - Putative threonine/serine exporter
GKLCFBDK_01168 7.21e-205 - - - K - - - LysR family
GKLCFBDK_01169 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKLCFBDK_01170 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKLCFBDK_01171 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKLCFBDK_01172 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
GKLCFBDK_01173 1.44e-202 mleR - - K - - - LysR family
GKLCFBDK_01174 1.17e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKLCFBDK_01175 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01176 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01177 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GKLCFBDK_01178 5.67e-297 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
GKLCFBDK_01179 4.12e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
GKLCFBDK_01180 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GKLCFBDK_01181 1.89e-123 - - - - - - - -
GKLCFBDK_01182 1.04e-33 - - - - - - - -
GKLCFBDK_01183 2.71e-81 asp1 - - S - - - Asp23 family, cell envelope-related function
GKLCFBDK_01184 8.92e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
GKLCFBDK_01186 9.14e-66 - - - - - - - -
GKLCFBDK_01187 6.1e-88 - - - S - - - Belongs to the HesB IscA family
GKLCFBDK_01188 1.81e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GKLCFBDK_01189 8.08e-110 - - - F - - - NUDIX domain
GKLCFBDK_01190 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKLCFBDK_01191 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKLCFBDK_01192 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKLCFBDK_01193 5.79e-214 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GKLCFBDK_01194 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKLCFBDK_01195 3.72e-205 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GKLCFBDK_01196 1.75e-181 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKLCFBDK_01197 5.1e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKLCFBDK_01198 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
GKLCFBDK_01199 1.16e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
GKLCFBDK_01200 1.95e-220 - - - E - - - lipolytic protein G-D-S-L family
GKLCFBDK_01201 6.38e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
GKLCFBDK_01202 1.05e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GKLCFBDK_01203 9.31e-117 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKLCFBDK_01204 1.41e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKLCFBDK_01205 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01206 1.04e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKLCFBDK_01207 3.87e-300 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GKLCFBDK_01208 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKLCFBDK_01209 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GKLCFBDK_01210 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GKLCFBDK_01211 8.94e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GKLCFBDK_01212 2.15e-83 - - - M - - - Lysin motif
GKLCFBDK_01213 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GKLCFBDK_01214 1.53e-245 - - - S - - - Helix-turn-helix domain
GKLCFBDK_01215 2.65e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKLCFBDK_01216 1.43e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKLCFBDK_01217 9.11e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKLCFBDK_01218 3.93e-177 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKLCFBDK_01219 2.13e-85 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKLCFBDK_01220 4.94e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GKLCFBDK_01221 7.61e-215 yitL - - S ko:K00243 - ko00000 S1 domain
GKLCFBDK_01222 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GKLCFBDK_01223 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GKLCFBDK_01224 7.94e-42 - - - S - - - Protein of unknown function (DUF2929)
GKLCFBDK_01225 1.92e-302 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKLCFBDK_01226 1.99e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKLCFBDK_01227 2.2e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GKLCFBDK_01228 2.06e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKLCFBDK_01229 5.12e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKLCFBDK_01230 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKLCFBDK_01231 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GKLCFBDK_01232 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GKLCFBDK_01233 1.76e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GKLCFBDK_01234 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKLCFBDK_01235 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GKLCFBDK_01236 2.58e-108 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKLCFBDK_01237 2.6e-234 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GKLCFBDK_01238 2.58e-228 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GKLCFBDK_01239 8.45e-120 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GKLCFBDK_01240 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GKLCFBDK_01241 4.19e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKLCFBDK_01242 1.2e-234 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKLCFBDK_01243 6.44e-90 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GKLCFBDK_01244 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GKLCFBDK_01245 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GKLCFBDK_01246 1.89e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01247 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKLCFBDK_01248 4.59e-215 - - - G - - - Phosphotransferase enzyme family
GKLCFBDK_01249 1.54e-100 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKLCFBDK_01250 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKLCFBDK_01251 7.97e-71 - - - - - - - -
GKLCFBDK_01252 1.43e-166 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GKLCFBDK_01253 1.62e-229 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GKLCFBDK_01254 7.92e-76 - - - - - - - -
GKLCFBDK_01256 1.37e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKLCFBDK_01257 1.44e-254 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
GKLCFBDK_01258 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKLCFBDK_01260 1.52e-261 - - - M - - - hydrolase, family 25
GKLCFBDK_01261 1.48e-81 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
GKLCFBDK_01262 1.41e-27 - - - - - - - -
GKLCFBDK_01266 4.97e-107 - - - S - - - Domain of unknown function (DUF2479)
GKLCFBDK_01268 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
GKLCFBDK_01269 2.63e-204 - - - S - - - Phage tail protein
GKLCFBDK_01270 0.0 - - - L - - - Phage tail tape measure protein TP901
GKLCFBDK_01271 9.13e-34 - - - - - - - -
GKLCFBDK_01272 4.31e-76 - - - - - - - -
GKLCFBDK_01273 4.03e-150 - - - - - - - -
GKLCFBDK_01274 3.85e-98 - - - - - - - -
GKLCFBDK_01275 4.37e-81 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GKLCFBDK_01276 1.29e-53 - - - S - - - Phage head-tail joining protein
GKLCFBDK_01277 2.72e-88 - - - S - - - Phage gp6-like head-tail connector protein
GKLCFBDK_01278 8.32e-256 - - - S - - - Phage capsid family
GKLCFBDK_01279 7.15e-148 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
GKLCFBDK_01280 1.86e-306 - - - S - - - Phage portal protein
GKLCFBDK_01284 0.0 terL - - S - - - overlaps another CDS with the same product name
GKLCFBDK_01285 6.89e-102 - - - L - - - Phage terminase, small subunit
GKLCFBDK_01286 2.32e-200 - - - L - - - HNH nucleases
GKLCFBDK_01288 8.92e-06 - - - - - - - -
GKLCFBDK_01289 7.43e-107 - - - S - - - Phage transcriptional regulator, ArpU family
GKLCFBDK_01293 5.83e-21 - - - - - - - -
GKLCFBDK_01295 1.89e-172 - - - - - - - -
GKLCFBDK_01296 9.76e-93 - - - - - - - -
GKLCFBDK_01298 9.46e-159 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
GKLCFBDK_01299 8.82e-168 - - - L - - - Belongs to the 'phage' integrase family
GKLCFBDK_01300 1.71e-176 - - - L - - - DnaD domain protein
GKLCFBDK_01303 6.3e-21 - - - - - - - -
GKLCFBDK_01305 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01306 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01307 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
GKLCFBDK_01308 3.8e-63 - - - - - - - -
GKLCFBDK_01309 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
GKLCFBDK_01310 1.26e-60 - - - - - - - -
GKLCFBDK_01311 1.64e-97 - - - S - - - Protein of unknown function (DUF805)
GKLCFBDK_01313 3.29e-43 higA - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein HigA
GKLCFBDK_01315 9.96e-23 - - - - - - - -
GKLCFBDK_01316 0.0 - - - L - - - PLD-like domain
GKLCFBDK_01318 2.43e-100 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKLCFBDK_01320 7.96e-185 psuK 2.7.1.83 - GK ko:K16328 ko00240,map00240 ko00000,ko00001,ko01000 Winged helix-turn-helix DNA-binding
GKLCFBDK_01321 5.22e-190 psuK 2.7.1.83 - G ko:K16328 ko00240,map00240 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
GKLCFBDK_01322 5.16e-152 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
GKLCFBDK_01323 2.91e-92 - - - S - - - Membrane
GKLCFBDK_01324 3.93e-228 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
GKLCFBDK_01325 4.08e-254 nupC - - F ko:K11535 - ko00000,ko02000 Na+ dependent nucleoside transporter C-terminus
GKLCFBDK_01327 3.42e-233 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
GKLCFBDK_01328 2.12e-253 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKLCFBDK_01329 2.23e-129 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GKLCFBDK_01330 7.55e-286 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GKLCFBDK_01331 7.81e-102 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKLCFBDK_01332 1.81e-146 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
GKLCFBDK_01333 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
GKLCFBDK_01334 2.07e-263 - - - G - - - Transporter, major facilitator family protein
GKLCFBDK_01335 7.08e-142 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
GKLCFBDK_01336 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
GKLCFBDK_01337 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKLCFBDK_01338 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GKLCFBDK_01339 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
GKLCFBDK_01340 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
GKLCFBDK_01341 3.14e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
GKLCFBDK_01342 4.55e-303 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
GKLCFBDK_01343 7.46e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKLCFBDK_01344 5.28e-105 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
GKLCFBDK_01345 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
GKLCFBDK_01346 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
GKLCFBDK_01347 1.64e-206 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GKLCFBDK_01348 5.87e-147 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
GKLCFBDK_01349 2.38e-50 - - - S - - - Cytochrome B5
GKLCFBDK_01350 9.85e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GKLCFBDK_01351 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
GKLCFBDK_01352 3.12e-191 - - - O - - - Band 7 protein
GKLCFBDK_01353 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
GKLCFBDK_01354 1.32e-165 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
GKLCFBDK_01355 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
GKLCFBDK_01356 1.78e-160 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
GKLCFBDK_01357 3.97e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKLCFBDK_01358 6.03e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GKLCFBDK_01359 2e-240 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GKLCFBDK_01360 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
GKLCFBDK_01361 5.52e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
GKLCFBDK_01362 1.48e-246 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKLCFBDK_01363 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GKLCFBDK_01364 8.14e-216 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GKLCFBDK_01365 1.72e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
GKLCFBDK_01366 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GKLCFBDK_01367 9.09e-113 ypmB - - S - - - Protein conserved in bacteria
GKLCFBDK_01368 2.38e-159 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GKLCFBDK_01369 2.42e-208 - - - EG - - - EamA-like transporter family
GKLCFBDK_01370 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GKLCFBDK_01371 1.41e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKLCFBDK_01372 2.38e-130 ypsA - - S - - - Belongs to the UPF0398 family
GKLCFBDK_01373 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKLCFBDK_01374 2.39e-108 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
GKLCFBDK_01375 1.03e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GKLCFBDK_01376 1.74e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
GKLCFBDK_01377 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
GKLCFBDK_01378 3.61e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKLCFBDK_01379 5.85e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKLCFBDK_01380 3.19e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
GKLCFBDK_01381 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GKLCFBDK_01382 0.0 FbpA - - K - - - Fibronectin-binding protein
GKLCFBDK_01383 2.95e-207 - - - S - - - EDD domain protein, DegV family
GKLCFBDK_01384 4.84e-124 - - - - - - - -
GKLCFBDK_01385 2.14e-154 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKLCFBDK_01386 1.78e-203 gspA - - M - - - family 8
GKLCFBDK_01387 5.98e-206 - - - S - - - Alpha beta hydrolase
GKLCFBDK_01388 9.11e-123 - - - K - - - Acetyltransferase (GNAT) domain
GKLCFBDK_01389 1.9e-311 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
GKLCFBDK_01390 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
GKLCFBDK_01391 4.73e-216 yvgN - - C - - - Aldo keto reductase
GKLCFBDK_01392 1.4e-206 rlrB - - K - - - LysR substrate binding domain protein
GKLCFBDK_01393 9.74e-108 - - - C - - - Flavodoxin
GKLCFBDK_01395 3.87e-97 - - - S - - - UPF0756 membrane protein
GKLCFBDK_01396 1.44e-309 - - - U - - - Belongs to the major facilitator superfamily
GKLCFBDK_01397 5.64e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
GKLCFBDK_01398 1.84e-316 yhdP - - S - - - Transporter associated domain
GKLCFBDK_01399 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
GKLCFBDK_01400 3.14e-187 - - - S - - - DUF218 domain
GKLCFBDK_01401 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKLCFBDK_01402 2.52e-76 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKLCFBDK_01403 6.04e-71 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKLCFBDK_01404 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GKLCFBDK_01405 1.18e-157 - - - S - - - SNARE associated Golgi protein
GKLCFBDK_01406 4.45e-292 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GKLCFBDK_01407 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKLCFBDK_01409 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
GKLCFBDK_01410 4.02e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GKLCFBDK_01411 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKLCFBDK_01412 5.13e-53 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
GKLCFBDK_01413 9.59e-96 - - - S - - - Protein of unknown function (DUF3290)
GKLCFBDK_01414 1.45e-149 - - - S - - - Protein of unknown function (DUF421)
GKLCFBDK_01415 7.29e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKLCFBDK_01416 5.89e-28 - - - - - - - -
GKLCFBDK_01417 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GKLCFBDK_01418 3.38e-193 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GKLCFBDK_01419 6.5e-63 yrvD - - S - - - Pfam:DUF1049
GKLCFBDK_01421 1.47e-41 - - - S - - - Phage derived protein Gp49-like (DUF891)
GKLCFBDK_01422 2.6e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
GKLCFBDK_01423 3.15e-207 - - - I - - - alpha/beta hydrolase fold
GKLCFBDK_01424 1.44e-146 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
GKLCFBDK_01425 1.29e-72 - - - - - - - -
GKLCFBDK_01428 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01429 4.32e-147 - - - S - - - Haloacid dehalogenase-like hydrolase
GKLCFBDK_01430 1.83e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKLCFBDK_01431 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKLCFBDK_01432 1.13e-219 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKLCFBDK_01433 2.13e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKLCFBDK_01434 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GKLCFBDK_01435 1.24e-182 - - - K - - - LysR substrate binding domain
GKLCFBDK_01436 8.18e-70 - - - S - - - branched-chain amino acid
GKLCFBDK_01437 8.37e-187 - - - E - - - AzlC protein
GKLCFBDK_01438 3.73e-264 hpk31 - - T - - - Histidine kinase
GKLCFBDK_01439 9.76e-161 vanR - - K - - - response regulator
GKLCFBDK_01440 7.28e-266 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKLCFBDK_01441 2.03e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
GKLCFBDK_01442 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GKLCFBDK_01443 4.73e-302 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
GKLCFBDK_01444 3.97e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKLCFBDK_01445 9.74e-154 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKLCFBDK_01446 2.57e-174 - - - S - - - Protein of unknown function (DUF1129)
GKLCFBDK_01447 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKLCFBDK_01448 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GKLCFBDK_01449 3.26e-196 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKLCFBDK_01450 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GKLCFBDK_01451 2.93e-197 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKLCFBDK_01452 1.88e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GKLCFBDK_01453 7.26e-209 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
GKLCFBDK_01454 2.47e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GKLCFBDK_01455 1.69e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
GKLCFBDK_01456 4.55e-288 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GKLCFBDK_01457 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01458 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKLCFBDK_01459 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKLCFBDK_01460 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKLCFBDK_01461 0.0 - - - M - - - Rib/alpha-like repeat
GKLCFBDK_01462 0.0 - - - M - - - Rib/alpha-like repeat
GKLCFBDK_01463 9.77e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKLCFBDK_01464 1.81e-275 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
GKLCFBDK_01465 1.87e-132 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
GKLCFBDK_01466 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKLCFBDK_01467 3.14e-231 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
GKLCFBDK_01468 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GKLCFBDK_01469 1.15e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKLCFBDK_01470 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GKLCFBDK_01471 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GKLCFBDK_01472 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GKLCFBDK_01473 0.0 - - - M - - - domain protein
GKLCFBDK_01474 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
GKLCFBDK_01475 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GKLCFBDK_01476 9.59e-92 - - - - - - - -
GKLCFBDK_01477 5.74e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKLCFBDK_01478 3.35e-228 - - - - - - - -
GKLCFBDK_01479 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKLCFBDK_01480 1.66e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GKLCFBDK_01481 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GKLCFBDK_01482 8.26e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKLCFBDK_01483 3.62e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GKLCFBDK_01484 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKLCFBDK_01485 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKLCFBDK_01486 1.56e-160 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKLCFBDK_01487 7.48e-49 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKLCFBDK_01488 3.96e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GKLCFBDK_01489 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKLCFBDK_01490 6.53e-271 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKLCFBDK_01491 8.95e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKLCFBDK_01492 9.38e-168 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
GKLCFBDK_01493 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GKLCFBDK_01494 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GKLCFBDK_01495 1.5e-220 ydbI - - K - - - AI-2E family transporter
GKLCFBDK_01496 1.54e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GKLCFBDK_01497 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01498 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
GKLCFBDK_01499 6.57e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKLCFBDK_01500 4.82e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GKLCFBDK_01501 4.43e-291 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GKLCFBDK_01502 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKLCFBDK_01503 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GKLCFBDK_01504 1.38e-37 - - - - - - - -
GKLCFBDK_01505 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GKLCFBDK_01506 2.59e-129 - - - S - - - Pfam:DUF3816
GKLCFBDK_01507 1.35e-182 - - - G - - - MucBP domain
GKLCFBDK_01508 1.66e-147 - - - - - - - -
GKLCFBDK_01509 5.71e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01510 7.18e-86 - - - K - - - Transcriptional regulator, GntR family
GKLCFBDK_01511 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01520 1.82e-86 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GKLCFBDK_01521 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
GKLCFBDK_01522 1.22e-125 - - - K - - - Acetyltransferase (GNAT) domain
GKLCFBDK_01523 5.43e-311 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
GKLCFBDK_01524 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GKLCFBDK_01525 1.37e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKLCFBDK_01526 1.91e-205 - - - O - - - Uncharacterized protein family (UPF0051)
GKLCFBDK_01527 5.32e-140 - - - M - - - LysM domain protein
GKLCFBDK_01528 0.0 - - - EP - - - Psort location Cytoplasmic, score
GKLCFBDK_01529 2.66e-138 - - - M - - - LysM domain protein
GKLCFBDK_01530 5.95e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GKLCFBDK_01531 2.31e-297 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GKLCFBDK_01532 3.25e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
GKLCFBDK_01533 6.12e-195 yeaE - - S - - - Aldo keto
GKLCFBDK_01534 4.45e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKLCFBDK_01535 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
GKLCFBDK_01536 7.91e-104 - - - S - - - Psort location Cytoplasmic, score
GKLCFBDK_01537 5.03e-111 - - - S - - - Short repeat of unknown function (DUF308)
GKLCFBDK_01538 7.03e-33 - - - - - - - -
GKLCFBDK_01539 6.81e-134 - - - V - - - VanZ like family
GKLCFBDK_01540 2.24e-299 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GKLCFBDK_01541 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GKLCFBDK_01542 0.0 - - - EGP - - - Major Facilitator
GKLCFBDK_01543 6.34e-121 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GKLCFBDK_01544 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKLCFBDK_01545 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GKLCFBDK_01546 1.2e-54 - - - - - - - -
GKLCFBDK_01547 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKLCFBDK_01548 2.91e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKLCFBDK_01549 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GKLCFBDK_01550 5.35e-113 - - - T - - - Belongs to the universal stress protein A family
GKLCFBDK_01551 1.26e-230 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKLCFBDK_01552 6.18e-150 dgk2 - - F - - - deoxynucleoside kinase
GKLCFBDK_01553 5.33e-147 - - - - - - - -
GKLCFBDK_01554 2.41e-236 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
GKLCFBDK_01555 8.45e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKLCFBDK_01556 1.52e-43 - - - - - - - -
GKLCFBDK_01557 5.21e-154 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKLCFBDK_01558 9.17e-59 - - - - - - - -
GKLCFBDK_01560 5.39e-92 - - - - - - - -
GKLCFBDK_01561 4.8e-72 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKLCFBDK_01562 6.21e-119 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GKLCFBDK_01563 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
GKLCFBDK_01564 1.32e-290 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GKLCFBDK_01565 9.56e-133 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GKLCFBDK_01566 8.62e-273 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
GKLCFBDK_01567 4.61e-61 - - - - - - - -
GKLCFBDK_01568 1.49e-54 - - - - - - - -
GKLCFBDK_01570 9.95e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKLCFBDK_01571 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKLCFBDK_01572 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GKLCFBDK_01573 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKLCFBDK_01574 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
GKLCFBDK_01575 1.77e-280 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GKLCFBDK_01576 0.0 yhaN - - L - - - AAA domain
GKLCFBDK_01577 1.22e-177 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKLCFBDK_01579 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
GKLCFBDK_01580 3.28e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01581 2.82e-280 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GKLCFBDK_01582 4.53e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKLCFBDK_01583 0.0 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
GKLCFBDK_01584 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GKLCFBDK_01585 1.57e-233 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
GKLCFBDK_01586 1.53e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKLCFBDK_01587 2.27e-75 - - - S - - - Small secreted protein
GKLCFBDK_01588 2.95e-75 ytpP - - CO - - - Thioredoxin
GKLCFBDK_01589 6.65e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKLCFBDK_01590 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GKLCFBDK_01591 2.17e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKLCFBDK_01592 5.87e-155 - - - S - - - Protein of unknown function (DUF1275)
GKLCFBDK_01593 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKLCFBDK_01594 9.55e-205 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKLCFBDK_01595 7.5e-132 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKLCFBDK_01596 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKLCFBDK_01597 1.04e-278 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
GKLCFBDK_01598 1.66e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GKLCFBDK_01599 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKLCFBDK_01600 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GKLCFBDK_01601 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKLCFBDK_01602 3.85e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GKLCFBDK_01603 5.44e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GKLCFBDK_01604 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
GKLCFBDK_01605 1.2e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKLCFBDK_01606 4.91e-144 yqeK - - H - - - Hydrolase, HD family
GKLCFBDK_01607 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKLCFBDK_01608 1.29e-178 yqeM - - Q - - - Methyltransferase
GKLCFBDK_01609 2.45e-267 ylbM - - S - - - Belongs to the UPF0348 family
GKLCFBDK_01610 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GKLCFBDK_01611 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GKLCFBDK_01612 5.62e-155 csrR - - K - - - response regulator
GKLCFBDK_01613 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKLCFBDK_01614 0.0 potE - - E - - - Amino Acid
GKLCFBDK_01615 4.82e-294 - - - V - - - MatE
GKLCFBDK_01616 6.2e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKLCFBDK_01617 2.74e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKLCFBDK_01618 1.21e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GKLCFBDK_01619 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01621 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKLCFBDK_01622 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GKLCFBDK_01623 1.1e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GKLCFBDK_01624 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKLCFBDK_01625 1.16e-108 - - - - - - - -
GKLCFBDK_01626 1.33e-47 - - - - - - - -
GKLCFBDK_01627 4.08e-132 - - - K - - - DNA-templated transcription, initiation
GKLCFBDK_01628 3.14e-167 - - - - - - - -
GKLCFBDK_01629 2.66e-88 - - - K - - - Transcriptional regulator, HxlR family
GKLCFBDK_01630 8.54e-223 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKLCFBDK_01631 2.03e-193 epsB - - M - - - biosynthesis protein
GKLCFBDK_01632 5.04e-157 ywqD - - D - - - Capsular exopolysaccharide family
GKLCFBDK_01633 1.26e-66 capM - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
GKLCFBDK_01634 1.15e-60 - - - M - - - Glycosyltransferase like family 2
GKLCFBDK_01635 6.03e-83 - - - - - - - -
GKLCFBDK_01637 4.46e-55 cps1B - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 transferase activity, transferring glycosyl groups
GKLCFBDK_01638 4.54e-38 - - - - - - - -
GKLCFBDK_01639 1.02e-160 - - - S - - - polysaccharide biosynthetic process
GKLCFBDK_01640 8.17e-208 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKLCFBDK_01641 9.64e-141 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GKLCFBDK_01642 1.34e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKLCFBDK_01643 2.08e-82 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GKLCFBDK_01644 9.39e-194 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKLCFBDK_01645 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
GKLCFBDK_01646 5.66e-128 - - - K - - - UTRA
GKLCFBDK_01647 1.43e-209 - - - O - - - ADP-ribosylglycohydrolase
GKLCFBDK_01648 2.36e-306 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
GKLCFBDK_01649 8.62e-150 - - - G - - - Belongs to the carbohydrate kinase PfkB family
GKLCFBDK_01651 3.71e-57 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
GKLCFBDK_01653 1.15e-34 - - - - - - - -
GKLCFBDK_01654 5.82e-57 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKLCFBDK_01656 1.27e-64 - - - S - - - Protein of unknown function (DUF4065)
GKLCFBDK_01658 2.66e-219 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GKLCFBDK_01659 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKLCFBDK_01661 1.71e-89 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
GKLCFBDK_01662 4.74e-51 - - - - ko:K18829 - ko00000,ko02048 -
GKLCFBDK_01664 3.4e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GKLCFBDK_01665 4.82e-226 - - - M - - - Glycosyl hydrolases family 25
GKLCFBDK_01666 7.54e-264 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GKLCFBDK_01667 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
GKLCFBDK_01668 1.02e-135 - - - L - - - nuclease
GKLCFBDK_01669 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKLCFBDK_01670 1.5e-91 - - - - - - - -
GKLCFBDK_01671 3.38e-132 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
GKLCFBDK_01672 8.65e-162 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKLCFBDK_01673 9.06e-195 - - - G - - - Belongs to the phosphoglycerate mutase family
GKLCFBDK_01674 7.72e-260 - - - - - - - -
GKLCFBDK_01676 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01677 4.82e-194 - - - S - - - Alpha beta hydrolase
GKLCFBDK_01678 1.5e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
GKLCFBDK_01679 8.73e-122 - - - K - - - Virulence activator alpha C-term
GKLCFBDK_01680 7.98e-83 - - - GM - - - NAD(P)H-binding
GKLCFBDK_01681 8.35e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
GKLCFBDK_01682 5.69e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GKLCFBDK_01683 6e-174 - - - K - - - Transcriptional regulator
GKLCFBDK_01684 6.96e-206 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GKLCFBDK_01685 6.78e-136 - - - K - - - Transcriptional regulator C-terminal region
GKLCFBDK_01686 7.3e-250 - - - S - - - membrane
GKLCFBDK_01687 2.22e-145 - - - GM - - - NAD(P)H-binding
GKLCFBDK_01688 1.01e-84 - - - - - - - -
GKLCFBDK_01689 4.02e-166 - - - F - - - glutamine amidotransferase
GKLCFBDK_01690 6.02e-184 - - - T - - - EAL domain
GKLCFBDK_01691 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
GKLCFBDK_01692 1.79e-111 - - - - - - - -
GKLCFBDK_01693 4.22e-255 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
GKLCFBDK_01694 3.83e-153 - - - T - - - Putative diguanylate phosphodiesterase
GKLCFBDK_01695 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GKLCFBDK_01696 8.28e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GKLCFBDK_01697 6.51e-122 - - - S - - - ECF transporter, substrate-specific component
GKLCFBDK_01698 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GKLCFBDK_01699 1.39e-143 - - - GM - - - NAD dependent epimerase dehydratase family protein
GKLCFBDK_01700 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GKLCFBDK_01701 2.43e-265 - - - EGP - - - Major Facilitator Superfamily
GKLCFBDK_01702 4.31e-296 - - - - - - - -
GKLCFBDK_01703 2.17e-107 - - - K - - - Transcriptional regulator, HxlR family
GKLCFBDK_01704 3.89e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
GKLCFBDK_01705 1.07e-66 ydeP - - K - - - Transcriptional regulator, HxlR family
GKLCFBDK_01706 7.79e-157 - - - GM - - - NmrA-like family
GKLCFBDK_01707 2.67e-101 - - - S ko:K02348 - ko00000 Gnat family
GKLCFBDK_01708 2.3e-52 - - - S - - - Cytochrome B5
GKLCFBDK_01709 8.47e-08 - - - S - - - Cytochrome B5
GKLCFBDK_01710 4.51e-54 - - - S - - - Cytochrome B5
GKLCFBDK_01711 1.94e-269 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GKLCFBDK_01713 5.69e-234 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKLCFBDK_01714 1.18e-315 - - - E ko:K03294 - ko00000 amino acid
GKLCFBDK_01715 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
GKLCFBDK_01716 2.99e-289 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
GKLCFBDK_01718 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKLCFBDK_01719 3.8e-80 - - - - - - - -
GKLCFBDK_01720 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GKLCFBDK_01721 1.16e-242 - - - E - - - Zinc-binding dehydrogenase
GKLCFBDK_01722 5.3e-113 - - - K - - - transcriptional regulator (TetR family)
GKLCFBDK_01723 2.5e-236 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GKLCFBDK_01724 1.05e-155 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01725 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01726 3.38e-50 - - - - - - - -
GKLCFBDK_01727 1.36e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GKLCFBDK_01728 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKLCFBDK_01729 1.54e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
GKLCFBDK_01730 2.6e-33 - - - - - - - -
GKLCFBDK_01731 2.83e-144 - - - - - - - -
GKLCFBDK_01732 2.12e-274 yttB - - EGP - - - Major Facilitator
GKLCFBDK_01733 1.38e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GKLCFBDK_01734 2.56e-115 - - - - - - - -
GKLCFBDK_01735 1.75e-141 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GKLCFBDK_01736 0.0 - - - S - - - Putative peptidoglycan binding domain
GKLCFBDK_01737 2.94e-161 - - - M - - - ErfK YbiS YcfS YnhG
GKLCFBDK_01739 4.75e-132 - - - - - - - -
GKLCFBDK_01740 1.02e-279 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKLCFBDK_01741 8.55e-187 - - - S - - - Alpha beta hydrolase
GKLCFBDK_01742 6.69e-263 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
GKLCFBDK_01743 8.39e-165 - - - G - - - Major Facilitator Superfamily
GKLCFBDK_01744 1.77e-162 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKLCFBDK_01745 4.31e-67 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GKLCFBDK_01746 2.95e-16 - - - G - - - Major Facilitator
GKLCFBDK_01747 1.42e-203 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKLCFBDK_01748 1.28e-44 - - - - - - - -
GKLCFBDK_01749 5.07e-199 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GKLCFBDK_01750 2.19e-135 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
GKLCFBDK_01751 9.99e-45 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKLCFBDK_01752 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKLCFBDK_01753 5.93e-55 - - - - - - - -
GKLCFBDK_01754 5.5e-161 pgm3 - - G - - - phosphoglycerate mutase family
GKLCFBDK_01755 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
GKLCFBDK_01756 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GKLCFBDK_01757 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GKLCFBDK_01758 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKLCFBDK_01759 6.75e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GKLCFBDK_01760 2.09e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKLCFBDK_01761 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
GKLCFBDK_01762 4.38e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GKLCFBDK_01763 7.25e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GKLCFBDK_01764 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
GKLCFBDK_01765 4.94e-122 - - - P - - - Cadmium resistance transporter
GKLCFBDK_01766 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01767 1.67e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKLCFBDK_01768 5.24e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GKLCFBDK_01769 2.27e-157 - - - M - - - PFAM NLP P60 protein
GKLCFBDK_01770 3.49e-93 - - - K - - - Transcriptional regulator, TetR family
GKLCFBDK_01772 1.76e-50 - - - M - - - Sortase family
GKLCFBDK_01773 7.78e-28 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GKLCFBDK_01774 2.67e-131 - - - S - - - Protein of unknown function (DUF3278)
GKLCFBDK_01775 1.28e-41 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
GKLCFBDK_01776 6.4e-65 - - - - - - - -
GKLCFBDK_01777 0.0 - - - S - - - ABC transporter, ATP-binding protein
GKLCFBDK_01778 1.89e-182 - - - S - - - Putative ABC-transporter type IV
GKLCFBDK_01779 2.97e-137 - - - NU - - - mannosyl-glycoprotein
GKLCFBDK_01780 5.41e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKLCFBDK_01781 1.14e-296 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GKLCFBDK_01782 7.5e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
GKLCFBDK_01784 1.69e-16 - - - K - - - Helix-turn-helix domain
GKLCFBDK_01786 0.000135 - - - - - - - -
GKLCFBDK_01787 1.51e-06 - - - L - - - Transposase
GKLCFBDK_01788 2.48e-66 - - - - - - - -
GKLCFBDK_01789 2.95e-174 - - - S - - - PD-(D/E)XK nuclease family transposase
GKLCFBDK_01791 3.32e-72 - - - - - - - -
GKLCFBDK_01792 9.26e-149 yrkL - - S - - - Flavodoxin-like fold
GKLCFBDK_01794 1.92e-86 yeaO - - S - - - Protein of unknown function, DUF488
GKLCFBDK_01795 2.34e-154 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GKLCFBDK_01796 1.98e-259 - - - S - - - associated with various cellular activities
GKLCFBDK_01797 2e-302 - - - S - - - Putative metallopeptidase domain
GKLCFBDK_01798 2.1e-64 - - - - - - - -
GKLCFBDK_01799 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GKLCFBDK_01800 5.02e-141 - - - K - - - Helix-turn-helix domain
GKLCFBDK_01801 7.31e-114 ymdB - - S - - - Macro domain protein
GKLCFBDK_01802 1.27e-253 - - - EGP - - - Major Facilitator
GKLCFBDK_01803 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKLCFBDK_01804 1.13e-68 - - - K - - - helix_turn_helix, mercury resistance
GKLCFBDK_01805 7.55e-213 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GKLCFBDK_01806 5.97e-203 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
GKLCFBDK_01807 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GKLCFBDK_01808 6.81e-172 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKLCFBDK_01809 3.86e-236 kinG - - T - - - Histidine kinase-like ATPases
GKLCFBDK_01810 6.42e-163 XK27_10500 - - K - - - response regulator
GKLCFBDK_01811 2.42e-200 yvgN - - S - - - Aldo keto reductase
GKLCFBDK_01812 1.38e-175 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GKLCFBDK_01813 4.74e-107 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKLCFBDK_01814 4.51e-261 - - - - - - - -
GKLCFBDK_01815 1.76e-68 - - - - - - - -
GKLCFBDK_01816 1.21e-48 - - - - - - - -
GKLCFBDK_01817 5.55e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
GKLCFBDK_01818 6.92e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKLCFBDK_01819 5.63e-227 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
GKLCFBDK_01820 4.21e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKLCFBDK_01821 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GKLCFBDK_01822 1.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKLCFBDK_01823 4.5e-135 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
GKLCFBDK_01824 7.14e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKLCFBDK_01825 8.05e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
GKLCFBDK_01826 6.65e-104 usp5 - - T - - - universal stress protein
GKLCFBDK_01827 2.73e-162 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GKLCFBDK_01828 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GKLCFBDK_01829 1.29e-54 - - - - - - - -
GKLCFBDK_01830 1.36e-121 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKLCFBDK_01831 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01832 1.15e-269 - - - M - - - ErfK YbiS YcfS YnhG
GKLCFBDK_01833 7.92e-20 - - - S - - - Domain of unknown function (DUF4767)
GKLCFBDK_01834 0.0 - - - M - - - NlpC/P60 family
GKLCFBDK_01835 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKLCFBDK_01836 3.09e-297 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKLCFBDK_01837 3.74e-232 yueF - - S - - - AI-2E family transporter
GKLCFBDK_01838 0.0 - - - G - - - Peptidase_C39 like family
GKLCFBDK_01839 1.06e-198 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKLCFBDK_01840 1.34e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKLCFBDK_01841 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GKLCFBDK_01842 8.17e-208 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKLCFBDK_01843 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKLCFBDK_01845 1.79e-169 - - - S - - - Psort location CytoplasmicMembrane, score
GKLCFBDK_01847 1.63e-92 - - - S - - - Bacterial membrane protein, YfhO
GKLCFBDK_01848 9.25e-12 - - - - - - - -
GKLCFBDK_01849 1.24e-112 - - - S - - - Glycosyltransferase like family
GKLCFBDK_01850 9.12e-111 - - - M - - - Domain of unknown function (DUF4422)
GKLCFBDK_01851 3.35e-53 - - - M - - - biosynthesis protein
GKLCFBDK_01852 1.09e-116 cps3F - - - - - - -
GKLCFBDK_01853 2.18e-129 - - - M - - - Glycosyltransferase like family 2
GKLCFBDK_01854 7.32e-140 - - - S - - - Glycosyltransferase like family 2
GKLCFBDK_01855 8.11e-97 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
GKLCFBDK_01856 9.79e-272 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GKLCFBDK_01857 3.02e-279 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GKLCFBDK_01858 3.89e-47 - - - - - - - -
GKLCFBDK_01859 0.0 - - - G - - - Peptidase_C39 like family
GKLCFBDK_01860 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
GKLCFBDK_01861 5.79e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GKLCFBDK_01862 1.29e-145 cps1D - - M - - - Domain of unknown function (DUF4422)
GKLCFBDK_01863 2.44e-127 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
GKLCFBDK_01864 5.17e-178 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GKLCFBDK_01865 2.53e-42 - - - - - - - -
GKLCFBDK_01866 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
GKLCFBDK_01867 2.05e-200 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GKLCFBDK_01868 0.0 potE - - E - - - Amino Acid
GKLCFBDK_01869 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GKLCFBDK_01870 2.3e-279 arcT - - E - - - Aminotransferase
GKLCFBDK_01871 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GKLCFBDK_01872 2.72e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GKLCFBDK_01873 4.94e-88 gtcA - - S - - - Teichoic acid glycosylation protein
GKLCFBDK_01874 1.02e-24 - - - - - - - -
GKLCFBDK_01875 1.43e-26 - - - - - - - -
GKLCFBDK_01876 5.74e-264 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKLCFBDK_01878 9.46e-298 yfmL - - L - - - DEAD DEAH box helicase
GKLCFBDK_01879 5.34e-245 mocA - - S - - - Oxidoreductase
GKLCFBDK_01880 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
GKLCFBDK_01881 2.87e-143 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GKLCFBDK_01882 2.64e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
GKLCFBDK_01883 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
GKLCFBDK_01884 7.71e-256 - - - S - - - Protein of unknown function (DUF3114)
GKLCFBDK_01885 2.73e-106 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
GKLCFBDK_01886 1.07e-151 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKLCFBDK_01887 8.49e-266 - - - P - - - Major Facilitator Superfamily
GKLCFBDK_01888 2.9e-26 - - - - - - - -
GKLCFBDK_01889 1.49e-102 - - - K - - - LytTr DNA-binding domain
GKLCFBDK_01890 6.48e-99 - - - S - - - Protein of unknown function (DUF3021)
GKLCFBDK_01891 2.36e-216 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GKLCFBDK_01892 4.59e-93 XK27_00915 - - C - - - Luciferase-like monooxygenase
GKLCFBDK_01893 2.68e-293 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKLCFBDK_01894 2.54e-101 - - - L ko:K07491 - ko00000 Transposase IS200 like
GKLCFBDK_01895 2.42e-38 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
GKLCFBDK_01896 6.17e-158 pnb - - C - - - nitroreductase
GKLCFBDK_01897 8.3e-117 - - - - - - - -
GKLCFBDK_01898 5.75e-115 XK27_07210 - - S - - - B3 4 domain
GKLCFBDK_01899 1.32e-315 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
GKLCFBDK_01900 8.89e-269 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GKLCFBDK_01901 1.19e-111 - - - S - - - PD-(D/E)XK nuclease family transposase
GKLCFBDK_01902 1.96e-64 - - - - - - - -
GKLCFBDK_01903 7.92e-250 - - - S - - - PFAM Archaeal ATPase
GKLCFBDK_01904 1.53e-77 - - - H - - - Riboflavin biosynthesis protein RibD
GKLCFBDK_01905 3.81e-218 - - - L - - - Plasmid pRiA4b ORF-3-like protein
GKLCFBDK_01907 2.92e-107 padR - - K - - - Transcriptional regulator PadR-like family
GKLCFBDK_01908 2.84e-313 - - - EGP - - - Major Facilitator
GKLCFBDK_01909 2.02e-138 - - - S - - - NADPH-dependent FMN reductase
GKLCFBDK_01910 2.12e-114 - - - K - - - Bacterial regulatory proteins, tetR family
GKLCFBDK_01911 9.51e-114 entB - - Q - - - Isochorismatase family
GKLCFBDK_01912 1.08e-83 - - - K - - - Psort location Cytoplasmic, score
GKLCFBDK_01913 1.5e-86 yjdF3 - - S - - - Protein of unknown function (DUF2992)
GKLCFBDK_01914 9.45e-266 - - - EGP - - - Major Facilitator
GKLCFBDK_01915 6.4e-59 - - - K - - - Bacterial regulatory proteins, tetR family
GKLCFBDK_01916 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKLCFBDK_01918 4.7e-238 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GKLCFBDK_01919 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKLCFBDK_01920 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKLCFBDK_01921 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKLCFBDK_01922 1.11e-260 camS - - S - - - sex pheromone
GKLCFBDK_01923 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKLCFBDK_01924 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GKLCFBDK_01925 3.63e-269 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKLCFBDK_01926 1.36e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKLCFBDK_01927 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GKLCFBDK_01928 1.56e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
GKLCFBDK_01929 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01930 3.88e-186 - - - L - - - PFAM transposase IS116 IS110 IS902
GKLCFBDK_01931 6.64e-187 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKLCFBDK_01932 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKLCFBDK_01933 8.23e-78 yodB - - K - - - Transcriptional regulator, HxlR family
GKLCFBDK_01934 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKLCFBDK_01935 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKLCFBDK_01936 1.02e-149 - - - M - - - PFAM NLP P60 protein
GKLCFBDK_01937 8.38e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GKLCFBDK_01938 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKLCFBDK_01939 5.43e-91 yneR - - S - - - Belongs to the HesB IscA family
GKLCFBDK_01940 0.0 - - - S - - - membrane
GKLCFBDK_01941 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKLCFBDK_01942 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKLCFBDK_01943 2.68e-129 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKLCFBDK_01944 2.79e-146 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
GKLCFBDK_01945 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GKLCFBDK_01946 2.51e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GKLCFBDK_01947 7.66e-88 yqhL - - P - - - Rhodanese-like protein
GKLCFBDK_01948 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
GKLCFBDK_01949 1.61e-223 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKLCFBDK_01950 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GKLCFBDK_01951 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKLCFBDK_01952 6.37e-278 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKLCFBDK_01953 1.28e-18 - - - - - - - -
GKLCFBDK_01955 1.39e-196 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKLCFBDK_01956 8.11e-131 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKLCFBDK_01957 1.27e-66 yitW - - S - - - Iron-sulfur cluster assembly protein
GKLCFBDK_01958 4.87e-203 - - - - - - - -
GKLCFBDK_01959 1.56e-234 - - - - - - - -
GKLCFBDK_01960 3.46e-115 - - - S - - - Protein conserved in bacteria
GKLCFBDK_01963 1.99e-146 - - - K - - - Transcriptional regulator
GKLCFBDK_01964 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GKLCFBDK_01965 5.08e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
GKLCFBDK_01966 4.17e-60 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GKLCFBDK_01967 1.29e-168 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKLCFBDK_01968 1.34e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GKLCFBDK_01969 4.63e-152 - - - J - - - 2'-5' RNA ligase superfamily
GKLCFBDK_01970 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GKLCFBDK_01971 4.51e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKLCFBDK_01972 1.13e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKLCFBDK_01973 1.81e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKLCFBDK_01974 9.86e-59 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKLCFBDK_01975 8.12e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKLCFBDK_01976 6.89e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GKLCFBDK_01977 1.11e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GKLCFBDK_01978 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GKLCFBDK_01979 9e-72 - - - - - - - -
GKLCFBDK_01980 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GKLCFBDK_01981 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKLCFBDK_01982 4.64e-275 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKLCFBDK_01983 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKLCFBDK_01984 2.47e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKLCFBDK_01985 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKLCFBDK_01986 1.05e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GKLCFBDK_01987 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKLCFBDK_01988 2.96e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKLCFBDK_01989 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GKLCFBDK_01990 1.06e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GKLCFBDK_01991 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GKLCFBDK_01992 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
GKLCFBDK_01993 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GKLCFBDK_01994 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKLCFBDK_01995 1.92e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKLCFBDK_01996 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKLCFBDK_01997 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKLCFBDK_01998 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GKLCFBDK_01999 1.61e-259 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKLCFBDK_02000 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKLCFBDK_02001 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKLCFBDK_02002 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GKLCFBDK_02003 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GKLCFBDK_02004 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKLCFBDK_02005 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GKLCFBDK_02006 0.0 - - - E ko:K03294 - ko00000 amino acid
GKLCFBDK_02007 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKLCFBDK_02008 6.23e-197 - - - L - - - Belongs to the 'phage' integrase family
GKLCFBDK_02009 2.75e-57 - - - - - - - -
GKLCFBDK_02011 5.16e-225 - - - - - - - -
GKLCFBDK_02012 6.18e-63 - - - L - - - nuclease
GKLCFBDK_02013 5.87e-27 - - - - - - - -
GKLCFBDK_02016 1.28e-46 - - - - - - - -
GKLCFBDK_02017 5.01e-69 - - - S - - - Mazg nucleotide pyrophosphohydrolase
GKLCFBDK_02018 3.75e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GKLCFBDK_02019 4.45e-109 - - - - - - - -
GKLCFBDK_02020 2.84e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKLCFBDK_02021 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GKLCFBDK_02022 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)