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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PHPPBHLC_00001	1.01e-294	-	-	-	P	-	-	-	Chloride transporter, ClC family
PHPPBHLC_00002	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PHPPBHLC_00003	9.77e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
PHPPBHLC_00014	2.65e-247	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PHPPBHLC_00015	4.37e-266	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
PHPPBHLC_00016	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PHPPBHLC_00017	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
PHPPBHLC_00018	8.18e-211	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
PHPPBHLC_00019	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHPPBHLC_00020	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHPPBHLC_00021	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PHPPBHLC_00023	0.0	-	-	-	M	-	-	-	Pfam:DUF1792
PHPPBHLC_00024	0.0	-	-	-	M	-	-	-	family 8
PHPPBHLC_00026	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PHPPBHLC_00027	3.13e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHPPBHLC_00028	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PHPPBHLC_00029	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PHPPBHLC_00030	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PHPPBHLC_00031	8.55e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
PHPPBHLC_00032	2.21e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PHPPBHLC_00033	2.21e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHPPBHLC_00034	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PHPPBHLC_00035	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
PHPPBHLC_00036	2.23e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PHPPBHLC_00037	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
PHPPBHLC_00038	8.94e-135	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
PHPPBHLC_00039	2.07e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
PHPPBHLC_00040	1.99e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
PHPPBHLC_00041	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
PHPPBHLC_00042	5.13e-61	-	-	-	-	-	-	-	-
PHPPBHLC_00043	1.33e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PHPPBHLC_00044	2.37e-110	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PHPPBHLC_00045	9.79e-29	-	-	-	-	-	-	-	-
PHPPBHLC_00046	1.65e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
PHPPBHLC_00047	4.16e-180	-	-	-	S	-	-	-	Membrane
PHPPBHLC_00048	1.34e-177	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PHPPBHLC_00049	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PHPPBHLC_00050	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PHPPBHLC_00051	8.88e-301	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PHPPBHLC_00052	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
PHPPBHLC_00053	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PHPPBHLC_00054	5.35e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PHPPBHLC_00055	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PHPPBHLC_00056	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHPPBHLC_00057	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHPPBHLC_00058	4.28e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PHPPBHLC_00059	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHPPBHLC_00060	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHPPBHLC_00061	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PHPPBHLC_00062	3.29e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PHPPBHLC_00063	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PHPPBHLC_00064	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PHPPBHLC_00065	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PHPPBHLC_00066	3.53e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PHPPBHLC_00067	8.48e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PHPPBHLC_00068	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PHPPBHLC_00069	7.72e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PHPPBHLC_00070	2.8e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PHPPBHLC_00071	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PHPPBHLC_00072	2.93e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00073	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PHPPBHLC_00074	1.23e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PHPPBHLC_00075	9.62e-317	ymfH	-	-	S	-	-	-	Peptidase M16
PHPPBHLC_00076	5.91e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
PHPPBHLC_00077	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHPPBHLC_00078	2.48e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PHPPBHLC_00079	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHPPBHLC_00080	9.31e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PHPPBHLC_00081	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHPPBHLC_00082	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHPPBHLC_00083	1.84e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHPPBHLC_00084	4.74e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHPPBHLC_00085	8.77e-242	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PHPPBHLC_00086	1.83e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PHPPBHLC_00087	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PHPPBHLC_00088	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHPPBHLC_00089	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHPPBHLC_00090	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PHPPBHLC_00091	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHPPBHLC_00092	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PHPPBHLC_00093	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
PHPPBHLC_00094	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHPPBHLC_00095	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PHPPBHLC_00096	1.43e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PHPPBHLC_00097	9.65e-180	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PHPPBHLC_00098	6.73e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHPPBHLC_00099	1.41e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PHPPBHLC_00100	6.01e-99	ykuL	-	-	S	-	-	-	(CBS) domain
PHPPBHLC_00101	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PHPPBHLC_00102	6.5e-190	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PHPPBHLC_00103	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHPPBHLC_00104	1.84e-75	-	-	-	-	-	-	-	-
PHPPBHLC_00105	7.6e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PHPPBHLC_00106	1.9e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PHPPBHLC_00107	9.88e-180	-	-	-	-	-	-	-	-
PHPPBHLC_00108	2.88e-167	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PHPPBHLC_00109	1.02e-235	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PHPPBHLC_00110	3.69e-234	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PHPPBHLC_00111	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PHPPBHLC_00112	2.89e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
PHPPBHLC_00113	2.38e-56	-	-	-	-	-	-	-	-
PHPPBHLC_00114	1.88e-91	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
PHPPBHLC_00116	4.88e-184	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PHPPBHLC_00117	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHPPBHLC_00118	2.17e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PHPPBHLC_00119	2.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PHPPBHLC_00120	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHPPBHLC_00121	3.91e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PHPPBHLC_00122	2.6e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PHPPBHLC_00125	7.1e-59	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHPPBHLC_00126	3.51e-308	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
PHPPBHLC_00127	2.47e-167	-	-	-	IQ	-	-	-	dehydrogenase reductase
PHPPBHLC_00128	4.54e-49	-	-	-	-	-	-	-	-
PHPPBHLC_00129	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PHPPBHLC_00130	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
PHPPBHLC_00131	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PHPPBHLC_00132	9.76e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHPPBHLC_00134	2.4e-130	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
PHPPBHLC_00135	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PHPPBHLC_00136	4.13e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHPPBHLC_00138	1.08e-183	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PHPPBHLC_00139	1.53e-110	-	-	-	S	-	-	-	Membrane
PHPPBHLC_00140	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PHPPBHLC_00141	3.98e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
PHPPBHLC_00142	3.45e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
PHPPBHLC_00143	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PHPPBHLC_00145	2.22e-312	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PHPPBHLC_00146	1.85e-69	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PHPPBHLC_00147	9.01e-164	-	-	-	-	-	-	-	-
PHPPBHLC_00148	2.76e-163	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PHPPBHLC_00149	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PHPPBHLC_00150	1.86e-287	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
PHPPBHLC_00151	4.44e-11	-	-	-	-	-	-	-	-
PHPPBHLC_00152	4.69e-200	-	-	-	GM	-	-	-	NAD(P)H-binding
PHPPBHLC_00153	6.68e-98	ywnA	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_00154	2.41e-205	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
PHPPBHLC_00155	1.24e-135	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHPPBHLC_00156	6.12e-182	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00157	1.48e-133	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
PHPPBHLC_00158	3.14e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PHPPBHLC_00159	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PHPPBHLC_00160	2.49e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PHPPBHLC_00161	7.14e-138	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHPPBHLC_00162	1.47e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHPPBHLC_00163	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PHPPBHLC_00164	2.59e-152	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
PHPPBHLC_00165	4.84e-199	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PHPPBHLC_00166	3.24e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PHPPBHLC_00167	1.47e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PHPPBHLC_00168	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
PHPPBHLC_00169	3.74e-58	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
PHPPBHLC_00170	2.83e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHPPBHLC_00171	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
PHPPBHLC_00172	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PHPPBHLC_00174	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHPPBHLC_00175	0.0	-	-	-	L	-	-	-	DNA helicase
PHPPBHLC_00176	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PHPPBHLC_00177	6.41e-236	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
PHPPBHLC_00178	1.3e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PHPPBHLC_00179	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PHPPBHLC_00180	4.99e-291	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PHPPBHLC_00181	1.33e-228	-	-	-	-	-	-	-	-
PHPPBHLC_00182	1.19e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PHPPBHLC_00184	7.54e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PHPPBHLC_00185	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHPPBHLC_00186	1.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PHPPBHLC_00187	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHPPBHLC_00188	6.92e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHPPBHLC_00189	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PHPPBHLC_00190	4.92e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PHPPBHLC_00191	7.03e-216	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PHPPBHLC_00192	1.98e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PHPPBHLC_00193	8.69e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
PHPPBHLC_00194	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PHPPBHLC_00195	7.77e-315	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHPPBHLC_00196	1.44e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHPPBHLC_00197	1.96e-101	-	-	-	-	-	-	-	-
PHPPBHLC_00198	1.95e-257	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PHPPBHLC_00199	1.14e-190	yidA	-	-	S	-	-	-	hydrolase
PHPPBHLC_00200	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PHPPBHLC_00201	2.07e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
PHPPBHLC_00202	6.79e-91	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PHPPBHLC_00203	2.68e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHPPBHLC_00204	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHPPBHLC_00205	2.25e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHPPBHLC_00206	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PHPPBHLC_00207	9.2e-303	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHPPBHLC_00208	5.56e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PHPPBHLC_00209	8.65e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PHPPBHLC_00210	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHPPBHLC_00211	9.19e-193	-	-	-	G	-	-	-	Right handed beta helix region
PHPPBHLC_00212	1.43e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHPPBHLC_00213	5.32e-208	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PHPPBHLC_00214	7.48e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PHPPBHLC_00215	6.66e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHPPBHLC_00216	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PHPPBHLC_00217	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PHPPBHLC_00218	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHPPBHLC_00219	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHPPBHLC_00220	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PHPPBHLC_00221	1.02e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PHPPBHLC_00222	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHPPBHLC_00223	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHPPBHLC_00224	2.71e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PHPPBHLC_00225	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHPPBHLC_00226	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PHPPBHLC_00227	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHPPBHLC_00228	2.66e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHPPBHLC_00229	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PHPPBHLC_00230	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PHPPBHLC_00231	6.02e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
PHPPBHLC_00232	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PHPPBHLC_00233	4.67e-146	-	-	-	S	-	-	-	(CBS) domain
PHPPBHLC_00234	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHPPBHLC_00235	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHPPBHLC_00236	3.11e-51	yabO	-	-	J	-	-	-	S4 domain protein
PHPPBHLC_00237	1.44e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PHPPBHLC_00238	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PHPPBHLC_00239	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHPPBHLC_00240	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PHPPBHLC_00241	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHPPBHLC_00242	2.77e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHPPBHLC_00243	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHPPBHLC_00244	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PHPPBHLC_00245	1.27e-110	-	-	-	-	-	-	-	-
PHPPBHLC_00258	3.54e-27	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PHPPBHLC_00259	2.75e-244	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PHPPBHLC_00260	4.72e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PHPPBHLC_00261	3.75e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHPPBHLC_00262	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PHPPBHLC_00263	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PHPPBHLC_00264	6.9e-77	-	-	-	-	-	-	-	-
PHPPBHLC_00265	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PHPPBHLC_00266	3.79e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHPPBHLC_00267	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PHPPBHLC_00268	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PHPPBHLC_00269	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHPPBHLC_00270	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHPPBHLC_00271	2.52e-261	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHPPBHLC_00272	4.49e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHPPBHLC_00273	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHPPBHLC_00274	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHPPBHLC_00275	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHPPBHLC_00276	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PHPPBHLC_00277	3.05e-189	ylmH	-	-	S	-	-	-	S4 domain protein
PHPPBHLC_00278	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PHPPBHLC_00279	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHPPBHLC_00280	3.3e-43	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PHPPBHLC_00281	5.85e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PHPPBHLC_00282	2.59e-25	-	-	-	-	-	-	-	-
PHPPBHLC_00283	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHPPBHLC_00284	5.23e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PHPPBHLC_00285	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PHPPBHLC_00286	8.77e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHPPBHLC_00287	3.3e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
PHPPBHLC_00288	3.82e-157	-	-	-	S	-	-	-	repeat protein
PHPPBHLC_00289	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHPPBHLC_00290	2.46e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHPPBHLC_00291	2.62e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PHPPBHLC_00292	4.09e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PHPPBHLC_00293	3.09e-177	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PHPPBHLC_00294	4.3e-68	-	-	-	-	-	-	-	-
PHPPBHLC_00295	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
PHPPBHLC_00296	7.67e-149	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PHPPBHLC_00297	1.01e-95	-	-	-	-	-	-	-	-
PHPPBHLC_00298	2.69e-228	-	-	-	-	-	-	-	-
PHPPBHLC_00299	3.48e-225	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PHPPBHLC_00300	1.15e-162	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PHPPBHLC_00301	1.77e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHPPBHLC_00302	3.46e-99	-	-	-	S	-	-	-	Flavodoxin
PHPPBHLC_00303	1.09e-82	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
PHPPBHLC_00304	3.75e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
PHPPBHLC_00305	3.7e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
PHPPBHLC_00306	1.81e-183	-	-	-	H	-	-	-	geranyltranstransferase activity
PHPPBHLC_00307	4.25e-222	-	-	-	-	-	-	-	-
PHPPBHLC_00308	2.19e-26	-	-	-	-	-	-	-	-
PHPPBHLC_00309	5.03e-148	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
PHPPBHLC_00310	1.55e-232	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
PHPPBHLC_00311	9.06e-60	-	-	-	-	-	-	-	-
PHPPBHLC_00312	6.2e-122	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PHPPBHLC_00313	1.25e-94	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
PHPPBHLC_00314	1.59e-284	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
PHPPBHLC_00315	1.36e-106	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
PHPPBHLC_00316	8.72e-235	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
PHPPBHLC_00317	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PHPPBHLC_00318	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
PHPPBHLC_00319	1.16e-127	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
PHPPBHLC_00320	9.45e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
PHPPBHLC_00321	1.33e-196	-	-	-	EG	-	-	-	EamA-like transporter family
PHPPBHLC_00322	1.15e-152	-	-	-	L	-	-	-	Integrase
PHPPBHLC_00323	4.19e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
PHPPBHLC_00324	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHPPBHLC_00326	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHPPBHLC_00327	2.75e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PHPPBHLC_00328	3.26e-227	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHPPBHLC_00329	1.02e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHPPBHLC_00330	3.39e-204	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PHPPBHLC_00331	6.78e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PHPPBHLC_00332	5.75e-285	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHPPBHLC_00333	5.1e-97	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHPPBHLC_00334	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHPPBHLC_00335	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PHPPBHLC_00336	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHPPBHLC_00337	8.95e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PHPPBHLC_00338	2.87e-170	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PHPPBHLC_00347	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_00348	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
PHPPBHLC_00349	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
PHPPBHLC_00350	2.47e-195	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PHPPBHLC_00351	1.57e-157	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PHPPBHLC_00353	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHPPBHLC_00354	5.56e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PHPPBHLC_00355	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PHPPBHLC_00356	2.91e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PHPPBHLC_00357	1.4e-283	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PHPPBHLC_00358	1.91e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
PHPPBHLC_00359	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PHPPBHLC_00360	1.33e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PHPPBHLC_00363	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PHPPBHLC_00364	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHPPBHLC_00365	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHPPBHLC_00366	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHPPBHLC_00367	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHPPBHLC_00368	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHPPBHLC_00369	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHPPBHLC_00370	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PHPPBHLC_00371	9.76e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PHPPBHLC_00372	1.64e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PHPPBHLC_00373	5.76e-247	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PHPPBHLC_00374	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHPPBHLC_00375	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHPPBHLC_00376	1.43e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHPPBHLC_00377	6.56e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHPPBHLC_00378	2.55e-215	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHPPBHLC_00379	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHPPBHLC_00380	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PHPPBHLC_00381	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
PHPPBHLC_00382	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
PHPPBHLC_00383	2.4e-298	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
PHPPBHLC_00384	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PHPPBHLC_00385	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PHPPBHLC_00386	1.03e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
PHPPBHLC_00387	1.86e-245	ampC	-	-	V	-	-	-	Beta-lactamase
PHPPBHLC_00388	5.26e-67	-	-	-	-	-	-	-	-
PHPPBHLC_00389	0.0	-	-	-	M	-	-	-	domain protein
PHPPBHLC_00390	6.08e-128	-	-	-	-	-	-	-	-
PHPPBHLC_00392	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PHPPBHLC_00393	1.28e-75	-	-	-	-	-	-	-	-
PHPPBHLC_00395	2.3e-115	-	-	-	-	-	-	-	-
PHPPBHLC_00396	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PHPPBHLC_00397	8.97e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
PHPPBHLC_00398	5.13e-70	-	-	-	S	-	-	-	Cupredoxin-like domain
PHPPBHLC_00399	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PHPPBHLC_00400	5.49e-207	-	-	-	EG	-	-	-	EamA-like transporter family
PHPPBHLC_00401	7.95e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
PHPPBHLC_00402	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PHPPBHLC_00403	2.15e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
PHPPBHLC_00404	5.47e-80	yisR1	3.2.1.23	-	K	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	helix_turn_helix, arabinose operon control protein
PHPPBHLC_00405	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
PHPPBHLC_00406	8.2e-300	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PHPPBHLC_00407	0.0	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
PHPPBHLC_00408	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
PHPPBHLC_00409	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
PHPPBHLC_00410	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
PHPPBHLC_00411	6.44e-302	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PHPPBHLC_00412	1.56e-170	-	-	-	GK	-	-	-	ROK family
PHPPBHLC_00413	0.0	-	-	-	G	-	-	-	Right handed beta helix region
PHPPBHLC_00414	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PHPPBHLC_00415	1.27e-222	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
PHPPBHLC_00416	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PHPPBHLC_00418	1.83e-277	xylR	-	-	GK	-	-	-	ROK family
PHPPBHLC_00419	2.49e-39	-	-	-	-	-	-	-	-
PHPPBHLC_00420	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PHPPBHLC_00421	9.95e-153	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PHPPBHLC_00422	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PHPPBHLC_00423	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PHPPBHLC_00424	5.68e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PHPPBHLC_00426	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
PHPPBHLC_00427	8.69e-188	-	-	-	S	-	-	-	Cof-like hydrolase
PHPPBHLC_00428	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_00429	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PHPPBHLC_00430	1.01e-67	-	-	-	-	-	-	-	-
PHPPBHLC_00431	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHPPBHLC_00432	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHPPBHLC_00433	1.11e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
PHPPBHLC_00434	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHPPBHLC_00435	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
PHPPBHLC_00436	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PHPPBHLC_00437	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHPPBHLC_00438	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PHPPBHLC_00439	6.15e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PHPPBHLC_00440	6.13e-100	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PHPPBHLC_00441	2.16e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHPPBHLC_00442	1.71e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PHPPBHLC_00443	3.97e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PHPPBHLC_00444	8.77e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHPPBHLC_00445	9.61e-137	-	-	-	-	-	-	-	-
PHPPBHLC_00446	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHPPBHLC_00447	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHPPBHLC_00448	3.43e-189	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
PHPPBHLC_00449	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PHPPBHLC_00450	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PHPPBHLC_00451	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PHPPBHLC_00452	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHPPBHLC_00453	1.02e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHPPBHLC_00454	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PHPPBHLC_00455	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHPPBHLC_00457	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHPPBHLC_00458	1.23e-309	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
PHPPBHLC_00459	1.83e-21	-	-	-	-	-	-	-	-
PHPPBHLC_00461	3.22e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PHPPBHLC_00462	6.97e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PHPPBHLC_00463	9.4e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PHPPBHLC_00464	9.18e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PHPPBHLC_00465	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHPPBHLC_00466	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHPPBHLC_00467	2.12e-19	-	-	-	-	-	-	-	-
PHPPBHLC_00468	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PHPPBHLC_00469	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PHPPBHLC_00470	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
PHPPBHLC_00471	1.91e-204	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
PHPPBHLC_00472	1.06e-258	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PHPPBHLC_00473	1.95e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHPPBHLC_00474	1.07e-203	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
PHPPBHLC_00475	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
PHPPBHLC_00476	4.31e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
PHPPBHLC_00477	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PHPPBHLC_00478	8.07e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PHPPBHLC_00479	1.03e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHPPBHLC_00480	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHPPBHLC_00481	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PHPPBHLC_00482	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
PHPPBHLC_00483	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHPPBHLC_00484	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHPPBHLC_00485	1.13e-120	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHPPBHLC_00486	2.01e-146	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PHPPBHLC_00487	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PHPPBHLC_00488	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_00489	1.88e-219	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PHPPBHLC_00490	1.52e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHPPBHLC_00491	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PHPPBHLC_00492	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
PHPPBHLC_00493	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHPPBHLC_00494	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_00495	2.89e-58	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHPPBHLC_00497	2.65e-07	-	-	-	K	-	-	-	Helix-turn-helix domain
PHPPBHLC_00498	4.85e-50	-	-	-	D	-	-	-	nuclear chromosome segregation
PHPPBHLC_00499	9.96e-52	-	-	-	V	-	-	-	Abi-like protein
PHPPBHLC_00501	1.71e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
PHPPBHLC_00507	2.51e-283	-	-	-	L	ko:K07487	-	ko00000	Transposase
PHPPBHLC_00508	1.36e-121	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHPPBHLC_00509	1.29e-54	-	-	-	-	-	-	-	-
PHPPBHLC_00510	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PHPPBHLC_00511	2.73e-162	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PHPPBHLC_00512	6.65e-104	usp5	-	-	T	-	-	-	universal stress protein
PHPPBHLC_00513	8.05e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
PHPPBHLC_00514	7.14e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PHPPBHLC_00515	4.5e-135	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
PHPPBHLC_00516	1.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PHPPBHLC_00517	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PHPPBHLC_00518	4.21e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PHPPBHLC_00519	5.63e-227	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PHPPBHLC_00520	6.92e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PHPPBHLC_00521	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PHPPBHLC_00522	1.21e-48	-	-	-	-	-	-	-	-
PHPPBHLC_00523	1.76e-68	-	-	-	-	-	-	-	-
PHPPBHLC_00524	4.51e-261	-	-	-	-	-	-	-	-
PHPPBHLC_00525	4.74e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHPPBHLC_00526	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PHPPBHLC_00527	2.42e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
PHPPBHLC_00528	6.42e-163	XK27_10500	-	-	K	-	-	-	response regulator
PHPPBHLC_00529	3.86e-236	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
PHPPBHLC_00530	6.81e-172	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00531	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PHPPBHLC_00532	5.97e-203	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PHPPBHLC_00533	7.55e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PHPPBHLC_00534	1.13e-68	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PHPPBHLC_00535	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHPPBHLC_00536	1.27e-253	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_00537	7.31e-114	ymdB	-	-	S	-	-	-	Macro domain protein
PHPPBHLC_00538	5.02e-141	-	-	-	K	-	-	-	Helix-turn-helix domain
PHPPBHLC_00539	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PHPPBHLC_00540	2.1e-64	-	-	-	-	-	-	-	-
PHPPBHLC_00541	2e-302	-	-	-	S	-	-	-	Putative metallopeptidase domain
PHPPBHLC_00542	1.98e-259	-	-	-	S	-	-	-	associated with various cellular activities
PHPPBHLC_00543	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PHPPBHLC_00544	1.92e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PHPPBHLC_00546	9.26e-149	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
PHPPBHLC_00547	3.32e-72	-	-	-	-	-	-	-	-
PHPPBHLC_00549	2.95e-174	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PHPPBHLC_00550	2.48e-66	-	-	-	-	-	-	-	-
PHPPBHLC_00551	1.51e-06	-	-	-	L	-	-	-	Transposase
PHPPBHLC_00552	0.000135	-	-	-	-	-	-	-	-
PHPPBHLC_00554	1.69e-16	-	-	-	K	-	-	-	Helix-turn-helix domain
PHPPBHLC_00556	7.5e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
PHPPBHLC_00557	1.14e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PHPPBHLC_00558	5.41e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PHPPBHLC_00559	2.97e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
PHPPBHLC_00560	1.89e-182	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PHPPBHLC_00561	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PHPPBHLC_00562	6.4e-65	-	-	-	-	-	-	-	-
PHPPBHLC_00563	1.28e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
PHPPBHLC_00564	2.67e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
PHPPBHLC_00565	7.78e-28	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PHPPBHLC_00566	1.76e-50	-	-	-	M	-	-	-	Sortase family
PHPPBHLC_00568	3.49e-93	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PHPPBHLC_00569	2.27e-157	-	-	-	M	-	-	-	PFAM NLP P60 protein
PHPPBHLC_00570	5.24e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PHPPBHLC_00571	1.67e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PHPPBHLC_00572	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00573	4.94e-122	-	-	-	P	-	-	-	Cadmium resistance transporter
PHPPBHLC_00574	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PHPPBHLC_00575	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PHPPBHLC_00576	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PHPPBHLC_00577	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
PHPPBHLC_00578	2.09e-214	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PHPPBHLC_00579	6.75e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PHPPBHLC_00580	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHPPBHLC_00581	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PHPPBHLC_00582	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PHPPBHLC_00583	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PHPPBHLC_00584	5.5e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
PHPPBHLC_00585	5.93e-55	-	-	-	-	-	-	-	-
PHPPBHLC_00586	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHPPBHLC_00587	9.99e-45	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PHPPBHLC_00588	2.19e-135	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
PHPPBHLC_00589	5.07e-199	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PHPPBHLC_00590	1.28e-44	-	-	-	-	-	-	-	-
PHPPBHLC_00591	1.42e-203	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PHPPBHLC_00592	2.95e-16	-	-	-	G	-	-	-	Major Facilitator
PHPPBHLC_00593	4.31e-67	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PHPPBHLC_00594	1.77e-162	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHPPBHLC_00595	8.39e-165	-	-	-	G	-	-	-	Major Facilitator Superfamily
PHPPBHLC_00596	6.69e-263	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
PHPPBHLC_00597	8.55e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
PHPPBHLC_00598	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PHPPBHLC_00599	4.75e-132	-	-	-	-	-	-	-	-
PHPPBHLC_00601	2.94e-161	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PHPPBHLC_00602	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PHPPBHLC_00603	1.75e-141	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PHPPBHLC_00604	2.56e-115	-	-	-	-	-	-	-	-
PHPPBHLC_00605	1.38e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PHPPBHLC_00606	2.12e-274	yttB	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_00607	2.83e-144	-	-	-	-	-	-	-	-
PHPPBHLC_00608	2.6e-33	-	-	-	-	-	-	-	-
PHPPBHLC_00609	1.54e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
PHPPBHLC_00610	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PHPPBHLC_00611	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PHPPBHLC_00612	3.38e-50	-	-	-	-	-	-	-	-
PHPPBHLC_00613	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00614	1.05e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00615	2.5e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PHPPBHLC_00616	5.3e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
PHPPBHLC_00617	1.16e-242	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
PHPPBHLC_00618	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PHPPBHLC_00619	3.8e-80	-	-	-	-	-	-	-	-
PHPPBHLC_00620	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHPPBHLC_00622	2.99e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PHPPBHLC_00623	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PHPPBHLC_00624	1.18e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
PHPPBHLC_00625	5.69e-234	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHPPBHLC_00626	1.94e-269	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PHPPBHLC_00627	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
PHPPBHLC_00628	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
PHPPBHLC_00629	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
PHPPBHLC_00630	2.67e-101	-	-	-	S	ko:K02348	-	ko00000	Gnat family
PHPPBHLC_00631	7.79e-157	-	-	-	GM	-	-	-	NmrA-like family
PHPPBHLC_00632	1.07e-66	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHPPBHLC_00633	3.89e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PHPPBHLC_00634	2.17e-107	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHPPBHLC_00635	4.31e-296	-	-	-	-	-	-	-	-
PHPPBHLC_00636	2.43e-265	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHPPBHLC_00637	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PHPPBHLC_00638	1.39e-143	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
PHPPBHLC_00639	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PHPPBHLC_00640	6.51e-122	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PHPPBHLC_00641	8.28e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PHPPBHLC_00642	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PHPPBHLC_00643	3.83e-153	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PHPPBHLC_00644	4.22e-255	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
PHPPBHLC_00645	1.79e-111	-	-	-	-	-	-	-	-
PHPPBHLC_00646	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PHPPBHLC_00647	6.02e-184	-	-	-	T	-	-	-	EAL domain
PHPPBHLC_00648	4.02e-166	-	-	-	F	-	-	-	glutamine amidotransferase
PHPPBHLC_00649	1.01e-84	-	-	-	-	-	-	-	-
PHPPBHLC_00650	2.22e-145	-	-	-	GM	-	-	-	NAD(P)H-binding
PHPPBHLC_00651	7.3e-250	-	-	-	S	-	-	-	membrane
PHPPBHLC_00652	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PHPPBHLC_00653	6.96e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PHPPBHLC_00654	6e-174	-	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_00655	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PHPPBHLC_00656	1.45e-72	-	-	-	L	-	-	-	Resolvase, N terminal domain
PHPPBHLC_00659	5.89e-104	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHPPBHLC_00660	7.84e-284	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PHPPBHLC_00661	4.9e-205	-	-	-	J	-	-	-	Methyltransferase
PHPPBHLC_00662	3.87e-164	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PHPPBHLC_00663	2.68e-129	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain
PHPPBHLC_00664	2.11e-165	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
PHPPBHLC_00665	2.93e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PHPPBHLC_00666	2.89e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PHPPBHLC_00667	7.91e-120	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PHPPBHLC_00668	4.36e-127	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
PHPPBHLC_00669	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
PHPPBHLC_00670	3.53e-297	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
PHPPBHLC_00671	1.06e-249	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PHPPBHLC_00672	3.36e-278	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHPPBHLC_00673	2.73e-248	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_00674	8.4e-162	-	-	-	M	-	-	-	Lysin motif
PHPPBHLC_00675	2.82e-105	-	-	-	-	-	-	-	-
PHPPBHLC_00676	4.02e-121	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
PHPPBHLC_00677	4.39e-267	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PHPPBHLC_00678	3.7e-19	-	-	-	-	-	-	-	-
PHPPBHLC_00679	8.83e-112	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PHPPBHLC_00680	3.39e-254	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PHPPBHLC_00681	3.08e-147	-	-	-	S	-	-	-	Membrane
PHPPBHLC_00682	1.1e-161	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
PHPPBHLC_00683	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHPPBHLC_00684	5.67e-198	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PHPPBHLC_00686	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_00687	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_00688	4.88e-300	-	-	-	L	-	-	-	Transposase
PHPPBHLC_00690	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PHPPBHLC_00691	8.23e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHPPBHLC_00692	5.67e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHPPBHLC_00693	1.19e-259	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PHPPBHLC_00694	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_00697	1.29e-72	-	-	-	-	-	-	-	-
PHPPBHLC_00698	1.44e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PHPPBHLC_00699	3.15e-207	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PHPPBHLC_00700	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHPPBHLC_00701	1.47e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
PHPPBHLC_00703	6.5e-63	yrvD	-	-	S	-	-	-	Pfam:DUF1049
PHPPBHLC_00704	3.38e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PHPPBHLC_00705	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PHPPBHLC_00706	5.89e-28	-	-	-	-	-	-	-	-
PHPPBHLC_00707	7.29e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PHPPBHLC_00708	1.45e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
PHPPBHLC_00709	9.59e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PHPPBHLC_00710	5.13e-53	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
PHPPBHLC_00711	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHPPBHLC_00712	4.02e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PHPPBHLC_00713	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PHPPBHLC_00715	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHPPBHLC_00716	4.45e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PHPPBHLC_00717	1.18e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
PHPPBHLC_00718	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PHPPBHLC_00719	6.04e-71	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHPPBHLC_00720	2.52e-76	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHPPBHLC_00721	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHPPBHLC_00722	3.14e-187	-	-	-	S	-	-	-	DUF218 domain
PHPPBHLC_00723	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
PHPPBHLC_00724	1.84e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
PHPPBHLC_00725	5.64e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PHPPBHLC_00726	1.44e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PHPPBHLC_00727	3.87e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
PHPPBHLC_00729	9.74e-108	-	-	-	C	-	-	-	Flavodoxin
PHPPBHLC_00730	1.4e-206	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
PHPPBHLC_00731	4.73e-216	yvgN	-	-	C	-	-	-	Aldo keto reductase
PHPPBHLC_00732	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PHPPBHLC_00733	1.9e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PHPPBHLC_00734	9.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHPPBHLC_00735	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
PHPPBHLC_00736	1.78e-203	gspA	-	-	M	-	-	-	family 8
PHPPBHLC_00737	2.14e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PHPPBHLC_00738	4.84e-124	-	-	-	-	-	-	-	-
PHPPBHLC_00739	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
PHPPBHLC_00740	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PHPPBHLC_00741	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PHPPBHLC_00742	3.19e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
PHPPBHLC_00743	5.85e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PHPPBHLC_00744	3.61e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHPPBHLC_00745	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
PHPPBHLC_00746	1.74e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PHPPBHLC_00747	1.03e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PHPPBHLC_00748	2.39e-108	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PHPPBHLC_00749	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHPPBHLC_00750	2.38e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PHPPBHLC_00751	1.41e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHPPBHLC_00752	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PHPPBHLC_00753	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
PHPPBHLC_00754	2.38e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PHPPBHLC_00755	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PHPPBHLC_00756	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PHPPBHLC_00757	1.72e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PHPPBHLC_00758	8.14e-216	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PHPPBHLC_00759	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PHPPBHLC_00760	1.48e-246	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHPPBHLC_00761	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PHPPBHLC_00762	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PHPPBHLC_00763	2e-240	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
PHPPBHLC_00764	6.03e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PHPPBHLC_00765	3.97e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PHPPBHLC_00766	1.78e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
PHPPBHLC_00767	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
PHPPBHLC_00768	1.32e-165	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
PHPPBHLC_00769	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
PHPPBHLC_00770	3.12e-191	-	-	-	O	-	-	-	Band 7 protein
PHPPBHLC_00771	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PHPPBHLC_00772	9.85e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PHPPBHLC_00773	2.38e-50	-	-	-	S	-	-	-	Cytochrome B5
PHPPBHLC_00774	5.87e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
PHPPBHLC_00775	1.64e-206	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PHPPBHLC_00776	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PHPPBHLC_00777	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PHPPBHLC_00778	5.28e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PHPPBHLC_00779	7.46e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHPPBHLC_00780	4.55e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PHPPBHLC_00781	3.14e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PHPPBHLC_00782	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
PHPPBHLC_00783	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PHPPBHLC_00784	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PHPPBHLC_00785	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PHPPBHLC_00786	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
PHPPBHLC_00787	7.08e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
PHPPBHLC_00788	2.07e-263	-	-	-	G	-	-	-	Transporter, major facilitator family protein
PHPPBHLC_00789	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PHPPBHLC_00790	1.81e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
PHPPBHLC_00791	7.81e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PHPPBHLC_00792	7.55e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PHPPBHLC_00793	2.23e-129	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PHPPBHLC_00794	2.12e-253	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PHPPBHLC_00795	3.42e-233	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
PHPPBHLC_00797	4.08e-254	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Na+ dependent nucleoside transporter C-terminus
PHPPBHLC_00798	3.93e-228	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PHPPBHLC_00799	2.91e-92	-	-	-	S	-	-	-	Membrane
PHPPBHLC_00800	5.16e-152	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
PHPPBHLC_00801	5.22e-190	psuK	2.7.1.83	-	G	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PHPPBHLC_00802	7.96e-185	psuK	2.7.1.83	-	GK	ko:K16328	ko00240,map00240	ko00000,ko00001,ko01000	Winged helix-turn-helix DNA-binding
PHPPBHLC_00804	2.43e-100	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHPPBHLC_00806	0.0	-	-	-	L	-	-	-	PLD-like domain
PHPPBHLC_00807	9.96e-23	-	-	-	-	-	-	-	-
PHPPBHLC_00809	3.29e-43	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
PHPPBHLC_00811	1.64e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PHPPBHLC_00812	1.26e-60	-	-	-	-	-	-	-	-
PHPPBHLC_00813	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
PHPPBHLC_00814	3.8e-63	-	-	-	-	-	-	-	-
PHPPBHLC_00815	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHPPBHLC_00816	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_00817	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHPPBHLC_00818	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHPPBHLC_00819	3.75e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PHPPBHLC_00820	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
PHPPBHLC_00821	2.32e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PHPPBHLC_00822	1.73e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
PHPPBHLC_00823	8.76e-202	-	-	-	V	-	-	-	(ABC) transporter
PHPPBHLC_00824	1.15e-116	-	-	-	GM	-	-	-	epimerase
PHPPBHLC_00825	8.71e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PHPPBHLC_00826	3.33e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_00827	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
PHPPBHLC_00828	2.7e-241	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
PHPPBHLC_00829	7.79e-197	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PHPPBHLC_00830	1.22e-206	-	-	-	-	-	-	-	-
PHPPBHLC_00831	2.41e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PHPPBHLC_00832	2.34e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPPBHLC_00833	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00834	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PHPPBHLC_00835	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHPPBHLC_00836	5.75e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHPPBHLC_00837	2.22e-173	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PHPPBHLC_00838	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PHPPBHLC_00839	2.13e-310	-	-	-	E	-	-	-	amino acid
PHPPBHLC_00840	6.38e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PHPPBHLC_00841	4.72e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PHPPBHLC_00842	8.19e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PHPPBHLC_00843	1.45e-312	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PHPPBHLC_00844	3.76e-214	-	-	-	GK	-	-	-	ROK family
PHPPBHLC_00845	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PHPPBHLC_00846	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
PHPPBHLC_00847	1.17e-247	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PHPPBHLC_00848	1.78e-83	-	-	-	-	-	-	-	-
PHPPBHLC_00849	3.18e-11	-	-	-	-	-	-	-	-
PHPPBHLC_00850	7.02e-34	-	-	-	K	-	-	-	ArsR family transcriptional regulator
PHPPBHLC_00851	1.11e-158	-	-	-	I	-	-	-	Serine aminopeptidase, S33
PHPPBHLC_00852	9.53e-151	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PHPPBHLC_00853	1.25e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHPPBHLC_00854	9.65e-271	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_00855	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
PHPPBHLC_00856	8.6e-225	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
PHPPBHLC_00857	2.85e-206	-	-	-	-	-	-	-	-
PHPPBHLC_00858	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_00859	1.78e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PHPPBHLC_00860	3.68e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PHPPBHLC_00861	1.98e-299	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
PHPPBHLC_00862	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PHPPBHLC_00863	6.5e-71	-	-	-	-	-	-	-	-
PHPPBHLC_00864	2.29e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PHPPBHLC_00865	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_00866	1.81e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PHPPBHLC_00867	8.5e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PHPPBHLC_00868	7.72e-178	-	-	-	IQ	-	-	-	KR domain
PHPPBHLC_00869	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
PHPPBHLC_00870	1.39e-232	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PHPPBHLC_00871	6.13e-174	-	-	-	S	-	-	-	Double zinc ribbon
PHPPBHLC_00872	1.25e-249	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PHPPBHLC_00873	4.37e-168	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PHPPBHLC_00874	2.2e-271	-	-	-	-	-	-	-	-
PHPPBHLC_00877	3.07e-190	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PHPPBHLC_00878	1.9e-147	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PHPPBHLC_00879	2.14e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
PHPPBHLC_00880	0.0	yagE	-	-	E	-	-	-	amino acid
PHPPBHLC_00881	2.93e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PHPPBHLC_00882	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PHPPBHLC_00883	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PHPPBHLC_00884	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHPPBHLC_00885	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHPPBHLC_00886	1.01e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHPPBHLC_00887	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHPPBHLC_00888	5.98e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHPPBHLC_00889	5.88e-295	-	-	-	-	-	-	-	-
PHPPBHLC_00890	1.07e-299	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PHPPBHLC_00891	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PHPPBHLC_00892	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
PHPPBHLC_00893	4.1e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PHPPBHLC_00894	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PHPPBHLC_00895	4.44e-36	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
PHPPBHLC_00896	1.14e-193	-	-	-	-	-	-	-	-
PHPPBHLC_00897	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
PHPPBHLC_00898	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
PHPPBHLC_00899	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
PHPPBHLC_00900	3.27e-230	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPPBHLC_00901	6.47e-10	-	-	-	S	-	-	-	CsbD-like
PHPPBHLC_00902	1.98e-42	-	-	-	S	-	-	-	Transglycosylase associated protein
PHPPBHLC_00903	6.05e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHPPBHLC_00904	3.87e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
PHPPBHLC_00905	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
PHPPBHLC_00906	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PHPPBHLC_00907	5.43e-311	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PHPPBHLC_00908	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PHPPBHLC_00909	6.71e-207	-	-	-	EG	-	-	-	EamA-like transporter family
PHPPBHLC_00910	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHPPBHLC_00911	2.48e-40	-	-	-	L	-	-	-	Transposase DDE domain
PHPPBHLC_00912	7.22e-167	-	-	-	L	-	-	-	Transposase DDE domain
PHPPBHLC_00913	9.01e-284	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHPPBHLC_00914	3.88e-59	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PHPPBHLC_00916	2.79e-32	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PHPPBHLC_00917	4.41e-52	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PHPPBHLC_00922	2.04e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PHPPBHLC_00923	4.35e-282	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PHPPBHLC_00925	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PHPPBHLC_00927	3.16e-229	-	-	-	-	-	-	-	-
PHPPBHLC_00928	6.88e-144	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PHPPBHLC_00930	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHPPBHLC_00931	8.91e-122	-	-	-	-	-	-	-	-
PHPPBHLC_00932	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHPPBHLC_00933	1.2e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHPPBHLC_00934	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PHPPBHLC_00935	9.24e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PHPPBHLC_00936	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PHPPBHLC_00937	1.48e-214	-	-	-	C	-	-	-	Aldo keto reductase
PHPPBHLC_00938	3.7e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PHPPBHLC_00939	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PHPPBHLC_00940	6.98e-266	-	-	-	P	-	-	-	Voltage gated chloride channel
PHPPBHLC_00941	3.77e-288	sptS	-	-	T	-	-	-	Histidine kinase
PHPPBHLC_00942	8.32e-149	dltr	-	-	K	-	-	-	response regulator
PHPPBHLC_00943	1.24e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PHPPBHLC_00944	2.26e-89	-	-	-	-	-	-	-	-
PHPPBHLC_00945	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PHPPBHLC_00946	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PHPPBHLC_00947	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PHPPBHLC_00948	3.74e-265	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PHPPBHLC_00949	2.2e-223	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
PHPPBHLC_00950	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PHPPBHLC_00951	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PHPPBHLC_00952	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHPPBHLC_00953	5.56e-136	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
PHPPBHLC_00955	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
PHPPBHLC_00956	8.68e-44	-	-	-	-	-	-	-	-
PHPPBHLC_00957	2.49e-276	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHPPBHLC_00958	1.48e-222	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPPBHLC_00959	2.79e-97	-	-	-	O	-	-	-	OsmC-like protein
PHPPBHLC_00962	2.23e-137	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PHPPBHLC_00963	3.81e-190	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PHPPBHLC_00966	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PHPPBHLC_00967	2.24e-66	-	-	-	-	-	-	-	-
PHPPBHLC_00968	1.53e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PHPPBHLC_00969	2.4e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PHPPBHLC_00970	3.52e-201	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PHPPBHLC_00971	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PHPPBHLC_00972	1.75e-188	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHPPBHLC_00973	5.08e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
PHPPBHLC_00974	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PHPPBHLC_00975	8.85e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
PHPPBHLC_00976	9.06e-125	-	-	-	S	-	-	-	reductase
PHPPBHLC_00978	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHPPBHLC_00979	9.36e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PHPPBHLC_00980	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
PHPPBHLC_00981	7.05e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PHPPBHLC_00982	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PHPPBHLC_00983	5.03e-193	yycI	-	-	S	-	-	-	YycH protein
PHPPBHLC_00984	0.0	yycH	-	-	S	-	-	-	YycH protein
PHPPBHLC_00985	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHPPBHLC_00986	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PHPPBHLC_00988	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PHPPBHLC_00989	2.2e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PHPPBHLC_00991	3.18e-157	-	-	-	S	-	-	-	Fic/DOC family
PHPPBHLC_00992	2.17e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
PHPPBHLC_00993	7.71e-81	-	-	-	-	-	-	-	-
PHPPBHLC_00994	7.93e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_00995	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PHPPBHLC_00996	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PHPPBHLC_00997	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PHPPBHLC_00998	4.88e-300	-	-	-	L	-	-	-	Transposase
PHPPBHLC_00999	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01000	1.74e-151	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PHPPBHLC_01001	6.09e-113	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PHPPBHLC_01002	2.21e-196	lysR	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_01003	8.7e-28	-	-	-	-	-	-	-	-
PHPPBHLC_01004	1.32e-111	-	-	-	C	-	-	-	Flavodoxin
PHPPBHLC_01005	1.12e-210	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
PHPPBHLC_01006	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PHPPBHLC_01007	1.62e-143	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PHPPBHLC_01008	1.99e-282	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PHPPBHLC_01009	1.04e-158	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
PHPPBHLC_01010	3.66e-167	yneE	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_01011	2e-117	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PHPPBHLC_01012	1.75e-294	-	-	-	T	-	-	-	GHKL domain
PHPPBHLC_01013	1.18e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PHPPBHLC_01014	2.22e-206	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PHPPBHLC_01015	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01016	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01020	9.06e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHPPBHLC_01021	9.75e-101	-	-	-	K	-	-	-	Peptidase S24-like
PHPPBHLC_01024	3.5e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF4231)
PHPPBHLC_01025	6.43e-89	-	-	-	S	-	-	-	MTH538 TIR-like domain (DUF1863)
PHPPBHLC_01026	3.87e-33	-	-	-	-	-	-	-	-
PHPPBHLC_01027	2.16e-286	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHPPBHLC_01028	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHPPBHLC_01029	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHPPBHLC_01030	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PHPPBHLC_01031	5.7e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHPPBHLC_01032	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHPPBHLC_01033	1.04e-83	-	-	-	-	-	-	-	-
PHPPBHLC_01034	4.45e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PHPPBHLC_01035	7.03e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHPPBHLC_01036	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHPPBHLC_01037	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHPPBHLC_01038	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
PHPPBHLC_01039	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PHPPBHLC_01040	2.39e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PHPPBHLC_01041	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PHPPBHLC_01042	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHPPBHLC_01043	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHPPBHLC_01044	8.1e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PHPPBHLC_01045	2.03e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PHPPBHLC_01046	1.5e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHPPBHLC_01047	1.27e-292	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PHPPBHLC_01048	8.54e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHPPBHLC_01049	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PHPPBHLC_01050	4.47e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHPPBHLC_01051	1.01e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PHPPBHLC_01052	6.88e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPPBHLC_01053	3.94e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PHPPBHLC_01054	1.14e-179	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PHPPBHLC_01055	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PHPPBHLC_01056	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PHPPBHLC_01057	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
PHPPBHLC_01058	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHPPBHLC_01059	5.56e-268	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PHPPBHLC_01060	8.42e-163	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHPPBHLC_01062	8.13e-22	-	-	-	-	-	-	-	-
PHPPBHLC_01063	1.69e-25	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PHPPBHLC_01064	9.02e-237	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
PHPPBHLC_01065	2.44e-180	-	-	-	S	-	-	-	Phage portal protein
PHPPBHLC_01066	6.53e-254	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PHPPBHLC_01067	2.33e-28	terS	-	-	L	-	-	-	Phage terminase, small subunit
PHPPBHLC_01068	8.12e-31	-	-	-	L	-	-	-	HNH endonuclease
PHPPBHLC_01071	1.69e-109	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
PHPPBHLC_01072	4.5e-53	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
PHPPBHLC_01080	0.000121	-	-	-	L	-	-	-	GIY-YIG catalytic domain
PHPPBHLC_01081	6.03e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHPPBHLC_01082	1.53e-122	-	-	-	-	-	-	-	-
PHPPBHLC_01083	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHPPBHLC_01084	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PHPPBHLC_01085	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
PHPPBHLC_01086	6.85e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHPPBHLC_01087	2.09e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHPPBHLC_01088	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHPPBHLC_01089	2.44e-20	-	-	-	-	-	-	-	-
PHPPBHLC_01090	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PHPPBHLC_01091	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PHPPBHLC_01092	5.06e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHPPBHLC_01093	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHPPBHLC_01094	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHPPBHLC_01095	2.52e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
PHPPBHLC_01096	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHPPBHLC_01097	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHPPBHLC_01098	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PHPPBHLC_01099	1.95e-201	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PHPPBHLC_01100	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PHPPBHLC_01101	1.43e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PHPPBHLC_01102	2.79e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PHPPBHLC_01103	5.2e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PHPPBHLC_01104	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHPPBHLC_01105	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PHPPBHLC_01106	2.6e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PHPPBHLC_01107	5.31e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PHPPBHLC_01108	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PHPPBHLC_01109	2.37e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PHPPBHLC_01110	2.02e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PHPPBHLC_01111	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PHPPBHLC_01112	1.06e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PHPPBHLC_01113	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PHPPBHLC_01114	4.05e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PHPPBHLC_01115	1.68e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHPPBHLC_01116	2.79e-107	-	-	-	-	-	-	-	-
PHPPBHLC_01117	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PHPPBHLC_01118	2.71e-235	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
PHPPBHLC_01119	4.37e-39	-	-	-	-	-	-	-	-
PHPPBHLC_01120	4.5e-241	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PHPPBHLC_01122	2.15e-75	-	-	-	-	-	-	-	-
PHPPBHLC_01123	2.42e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PHPPBHLC_01124	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHPPBHLC_01125	2.06e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHPPBHLC_01126	3.67e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHPPBHLC_01127	3.25e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHPPBHLC_01128	7.77e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHPPBHLC_01129	6.24e-110	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHPPBHLC_01130	4.77e-316	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHPPBHLC_01131	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PHPPBHLC_01132	1.92e-220	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PHPPBHLC_01133	2.82e-63	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_01134	3.24e-77	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_01135	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01136	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PHPPBHLC_01137	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHPPBHLC_01138	1.23e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHPPBHLC_01139	3.51e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHPPBHLC_01140	3.54e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHPPBHLC_01141	1.43e-185	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHPPBHLC_01142	1.34e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PHPPBHLC_01143	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHPPBHLC_01144	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHPPBHLC_01145	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHPPBHLC_01146	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PHPPBHLC_01147	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHPPBHLC_01148	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHPPBHLC_01149	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHPPBHLC_01150	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PHPPBHLC_01151	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PHPPBHLC_01152	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHPPBHLC_01153	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHPPBHLC_01154	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHPPBHLC_01155	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHPPBHLC_01156	3.02e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHPPBHLC_01157	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHPPBHLC_01158	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHPPBHLC_01159	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHPPBHLC_01160	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PHPPBHLC_01161	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHPPBHLC_01162	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHPPBHLC_01163	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHPPBHLC_01164	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHPPBHLC_01165	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHPPBHLC_01166	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHPPBHLC_01167	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PHPPBHLC_01168	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHPPBHLC_01169	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PHPPBHLC_01170	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHPPBHLC_01171	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHPPBHLC_01172	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHPPBHLC_01173	4.63e-152	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PHPPBHLC_01174	2.43e-265	-	-	-	-	-	-	-	-
PHPPBHLC_01175	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHPPBHLC_01176	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHPPBHLC_01177	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHPPBHLC_01178	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHPPBHLC_01179	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PHPPBHLC_01180	5.17e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PHPPBHLC_01181	1.69e-231	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PHPPBHLC_01182	4.07e-13	-	-	-	-	-	-	-	-
PHPPBHLC_01188	1.29e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PHPPBHLC_01189	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PHPPBHLC_01190	2.35e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PHPPBHLC_01191	6.58e-152	-	-	-	I	-	-	-	phosphatase
PHPPBHLC_01192	1.06e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PHPPBHLC_01193	2.44e-165	-	-	-	S	-	-	-	Putative threonine/serine exporter
PHPPBHLC_01194	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PHPPBHLC_01195	1.34e-160	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
PHPPBHLC_01196	2.85e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PHPPBHLC_01197	1.27e-152	-	-	-	S	-	-	-	membrane
PHPPBHLC_01198	5.5e-141	-	-	-	S	-	-	-	VIT family
PHPPBHLC_01199	2.79e-107	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PHPPBHLC_01200	1.14e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01201	1.34e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHPPBHLC_01202	7.44e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHPPBHLC_01203	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHPPBHLC_01204	3.85e-280	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PHPPBHLC_01205	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHPPBHLC_01206	1.58e-72	-	-	-	-	-	-	-	-
PHPPBHLC_01207	1.26e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PHPPBHLC_01208	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PHPPBHLC_01209	2.33e-154	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PHPPBHLC_01210	5.1e-207	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PHPPBHLC_01212	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHPPBHLC_01213	3.74e-120	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PHPPBHLC_01214	4.54e-240	-	-	-	I	-	-	-	Alpha beta
PHPPBHLC_01215	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_01216	1.34e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PHPPBHLC_01217	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PHPPBHLC_01218	7.21e-205	-	-	-	K	-	-	-	LysR family
PHPPBHLC_01219	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PHPPBHLC_01220	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PHPPBHLC_01221	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PHPPBHLC_01222	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PHPPBHLC_01223	1.44e-202	mleR	-	-	K	-	-	-	LysR family
PHPPBHLC_01224	1.17e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHPPBHLC_01225	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01226	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01227	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PHPPBHLC_01228	5.67e-297	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PHPPBHLC_01229	4.12e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
PHPPBHLC_01230	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PHPPBHLC_01231	1.89e-123	-	-	-	-	-	-	-	-
PHPPBHLC_01232	1.04e-33	-	-	-	-	-	-	-	-
PHPPBHLC_01233	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PHPPBHLC_01234	8.92e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PHPPBHLC_01236	9.14e-66	-	-	-	-	-	-	-	-
PHPPBHLC_01237	6.1e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
PHPPBHLC_01238	1.81e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PHPPBHLC_01239	8.08e-110	-	-	-	F	-	-	-	NUDIX domain
PHPPBHLC_01240	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHPPBHLC_01241	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHPPBHLC_01242	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHPPBHLC_01243	5.79e-214	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PHPPBHLC_01244	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHPPBHLC_01245	3.72e-205	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PHPPBHLC_01246	1.75e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHPPBHLC_01247	5.1e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHPPBHLC_01248	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PHPPBHLC_01249	1.16e-140	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PHPPBHLC_01250	1.95e-220	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PHPPBHLC_01251	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PHPPBHLC_01252	1.05e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PHPPBHLC_01253	9.31e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHPPBHLC_01254	1.41e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHPPBHLC_01255	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01256	1.04e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHPPBHLC_01257	3.87e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PHPPBHLC_01258	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHPPBHLC_01259	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PHPPBHLC_01260	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PHPPBHLC_01261	8.94e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PHPPBHLC_01262	2.15e-83	-	-	-	M	-	-	-	Lysin motif
PHPPBHLC_01263	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PHPPBHLC_01264	1.53e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
PHPPBHLC_01265	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHPPBHLC_01266	1.43e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PHPPBHLC_01267	9.11e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHPPBHLC_01268	3.93e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHPPBHLC_01269	2.13e-85	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHPPBHLC_01270	4.94e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PHPPBHLC_01271	7.61e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PHPPBHLC_01272	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PHPPBHLC_01273	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PHPPBHLC_01274	7.94e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PHPPBHLC_01275	1.92e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PHPPBHLC_01276	1.99e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHPPBHLC_01277	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PHPPBHLC_01278	2.06e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHPPBHLC_01279	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHPPBHLC_01280	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHPPBHLC_01281	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PHPPBHLC_01282	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PHPPBHLC_01283	1.76e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PHPPBHLC_01284	2.66e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHPPBHLC_01285	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PHPPBHLC_01286	2.58e-108	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHPPBHLC_01287	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PHPPBHLC_01288	2.58e-228	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHPPBHLC_01289	8.45e-120	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PHPPBHLC_01290	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PHPPBHLC_01291	4.19e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PHPPBHLC_01292	1.2e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHPPBHLC_01293	6.44e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PHPPBHLC_01294	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PHPPBHLC_01295	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PHPPBHLC_01296	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01297	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHPPBHLC_01298	4.59e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
PHPPBHLC_01299	1.54e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHPPBHLC_01300	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHPPBHLC_01301	7.97e-71	-	-	-	-	-	-	-	-
PHPPBHLC_01302	1.43e-166	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PHPPBHLC_01303	1.62e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PHPPBHLC_01304	7.92e-76	-	-	-	-	-	-	-	-
PHPPBHLC_01306	1.37e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PHPPBHLC_01307	1.44e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
PHPPBHLC_01308	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHPPBHLC_01310	1.52e-261	-	-	-	M	-	-	-	hydrolase, family 25
PHPPBHLC_01311	1.48e-81	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PHPPBHLC_01312	1.41e-27	-	-	-	-	-	-	-	-
PHPPBHLC_01316	4.97e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
PHPPBHLC_01318	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
PHPPBHLC_01319	2.63e-204	-	-	-	S	-	-	-	Phage tail protein
PHPPBHLC_01320	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PHPPBHLC_01321	9.13e-34	-	-	-	-	-	-	-	-
PHPPBHLC_01322	4.31e-76	-	-	-	-	-	-	-	-
PHPPBHLC_01323	4.03e-150	-	-	-	-	-	-	-	-
PHPPBHLC_01324	3.85e-98	-	-	-	-	-	-	-	-
PHPPBHLC_01325	4.37e-81	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PHPPBHLC_01326	1.29e-53	-	-	-	S	-	-	-	Phage head-tail joining protein
PHPPBHLC_01327	2.72e-88	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PHPPBHLC_01328	8.32e-256	-	-	-	S	-	-	-	Phage capsid family
PHPPBHLC_01329	7.15e-148	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
PHPPBHLC_01330	1.86e-306	-	-	-	S	-	-	-	Phage portal protein
PHPPBHLC_01334	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PHPPBHLC_01335	6.89e-102	-	-	-	L	-	-	-	Phage terminase, small subunit
PHPPBHLC_01336	2.32e-200	-	-	-	L	-	-	-	HNH nucleases
PHPPBHLC_01338	8.92e-06	-	-	-	-	-	-	-	-
PHPPBHLC_01339	7.43e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
PHPPBHLC_01343	5.83e-21	-	-	-	-	-	-	-	-
PHPPBHLC_01345	1.89e-172	-	-	-	-	-	-	-	-
PHPPBHLC_01346	9.76e-93	-	-	-	-	-	-	-	-
PHPPBHLC_01348	9.46e-159	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PHPPBHLC_01349	8.82e-168	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHPPBHLC_01350	1.71e-176	-	-	-	L	-	-	-	DnaD domain protein
PHPPBHLC_01353	6.3e-21	-	-	-	-	-	-	-	-
PHPPBHLC_01355	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01356	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01357	4.7e-264	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
PHPPBHLC_01358	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
PHPPBHLC_01359	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PHPPBHLC_01362	6.92e-31	-	-	-	-	-	-	-	-
PHPPBHLC_01363	5.22e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PHPPBHLC_01364	7.62e-97	-	-	-	-	-	-	-	-
PHPPBHLC_01365	4.68e-281	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PHPPBHLC_01366	1.37e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
PHPPBHLC_01367	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PHPPBHLC_01368	1.81e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PHPPBHLC_01369	0.0	arcT	-	-	E	-	-	-	Dipeptidase
PHPPBHLC_01370	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PHPPBHLC_01371	6.1e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PHPPBHLC_01372	4.16e-216	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PHPPBHLC_01373	3.17e-175	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PHPPBHLC_01374	2.04e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PHPPBHLC_01375	1.76e-122	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PHPPBHLC_01376	5.35e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PHPPBHLC_01377	2.69e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PHPPBHLC_01378	5.66e-295	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PHPPBHLC_01381	1.46e-59	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PHPPBHLC_01382	4.22e-111	-	-	-	Q	-	-	-	Methyltransferase
PHPPBHLC_01383	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
PHPPBHLC_01384	4.77e-305	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PHPPBHLC_01385	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PHPPBHLC_01386	1.05e-176	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PHPPBHLC_01387	9.4e-280	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PHPPBHLC_01388	2.89e-309	-	-	-	M	-	-	-	Glycosyl transferase
PHPPBHLC_01389	2.69e-196	-	-	-	-	-	-	-	-
PHPPBHLC_01390	3.02e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PHPPBHLC_01391	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHPPBHLC_01392	2.58e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PHPPBHLC_01393	9.65e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PHPPBHLC_01394	2.33e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PHPPBHLC_01395	1.69e-169	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
PHPPBHLC_01396	3.28e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHPPBHLC_01397	9.97e-185	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PHPPBHLC_01398	2.14e-234	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
PHPPBHLC_01399	1.46e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHPPBHLC_01400	2e-56	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHPPBHLC_01401	3.9e-208	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PHPPBHLC_01402	1.4e-145	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PHPPBHLC_01403	1.69e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PHPPBHLC_01404	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PHPPBHLC_01405	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
PHPPBHLC_01406	1.15e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
PHPPBHLC_01407	8.76e-63	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
PHPPBHLC_01408	1.03e-127	-	-	-	S	-	-	-	AmiS/UreI family transporter
PHPPBHLC_01409	1.86e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PHPPBHLC_01411	3.04e-234	-	-	-	-	-	-	-	-
PHPPBHLC_01412	9.45e-126	-	-	-	K	-	-	-	acetyltransferase
PHPPBHLC_01413	1.61e-184	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PHPPBHLC_01414	2.52e-206	-	-	-	K	-	-	-	LysR substrate binding domain
PHPPBHLC_01415	4.05e-266	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
PHPPBHLC_01416	9.99e-83	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHPPBHLC_01417	3.58e-237	-	-	-	-	-	-	-	-
PHPPBHLC_01418	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHPPBHLC_01419	1.26e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PHPPBHLC_01420	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_01421	4.88e-300	-	-	-	L	-	-	-	Transposase
PHPPBHLC_01422	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01423	4.82e-194	-	-	-	S	-	-	-	Alpha beta hydrolase
PHPPBHLC_01424	1.5e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
PHPPBHLC_01425	8.73e-122	-	-	-	K	-	-	-	Virulence activator alpha C-term
PHPPBHLC_01426	7.98e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
PHPPBHLC_01427	8.35e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PHPPBHLC_01428	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01429	3.54e-140	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PHPPBHLC_01430	9.26e-33	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
PHPPBHLC_01431	4.87e-47	-	-	-	C	-	-	-	Nitroreductase family
PHPPBHLC_01432	6.72e-303	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_01433	2.16e-89	-	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_01434	2.63e-53	-	-	-	-	-	-	-	-
PHPPBHLC_01435	0.0	ydaO	-	-	E	-	-	-	amino acid
PHPPBHLC_01436	0.0	-	-	-	E	-	-	-	amino acid
PHPPBHLC_01437	3.23e-108	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PHPPBHLC_01438	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHPPBHLC_01439	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHPPBHLC_01440	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHPPBHLC_01441	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PHPPBHLC_01442	8.05e-231	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHPPBHLC_01443	3.46e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHPPBHLC_01444	2.69e-183	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
PHPPBHLC_01445	1.8e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHPPBHLC_01446	6.03e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PHPPBHLC_01447	4.4e-171	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHPPBHLC_01448	4.1e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHPPBHLC_01449	2.48e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PHPPBHLC_01450	3.12e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PHPPBHLC_01451	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PHPPBHLC_01452	5.83e-225	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PHPPBHLC_01453	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PHPPBHLC_01454	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PHPPBHLC_01455	2.58e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PHPPBHLC_01456	4.69e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHPPBHLC_01457	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PHPPBHLC_01458	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PHPPBHLC_01459	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PHPPBHLC_01460	3.17e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHPPBHLC_01461	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PHPPBHLC_01462	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHPPBHLC_01463	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHPPBHLC_01464	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHPPBHLC_01465	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHPPBHLC_01466	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PHPPBHLC_01467	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHPPBHLC_01468	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHPPBHLC_01469	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PHPPBHLC_01470	1.11e-283	-	-	-	L	ko:K07487	-	ko00000	Transposase
PHPPBHLC_01471	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01472	2.48e-152	-	-	-	H	-	-	-	RibD C-terminal domain
PHPPBHLC_01476	3.44e-282	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PHPPBHLC_01477	4.19e-154	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PHPPBHLC_01478	2.99e-114	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PHPPBHLC_01479	1.34e-72	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PHPPBHLC_01480	4.26e-249	flp	-	-	V	-	-	-	Beta-lactamase
PHPPBHLC_01481	2.6e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PHPPBHLC_01482	1.69e-159	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PHPPBHLC_01483	2.07e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PHPPBHLC_01484	3.37e-162	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PHPPBHLC_01485	2.75e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PHPPBHLC_01486	2.15e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHPPBHLC_01487	8.04e-191	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
PHPPBHLC_01489	3.05e-44	-	-	-	-	-	-	-	-
PHPPBHLC_01490	4.17e-156	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PHPPBHLC_01491	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
PHPPBHLC_01492	6.55e-155	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
PHPPBHLC_01493	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
PHPPBHLC_01494	0.0	-	-	-	S	-	-	-	amidohydrolase
PHPPBHLC_01495	4.95e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PHPPBHLC_01496	1.51e-182	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHPPBHLC_01497	3.48e-212	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PHPPBHLC_01498	8.65e-59	-	-	-	M	-	-	-	Glycosyl transferases group 1
PHPPBHLC_01499	1.36e-52	-	-	-	M	-	-	-	Glycosyl transferases group 1
PHPPBHLC_01501	1.58e-204	-	-	-	S	-	-	-	reductase
PHPPBHLC_01502	7.3e-113	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
PHPPBHLC_01503	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PHPPBHLC_01504	3.61e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PHPPBHLC_01505	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHPPBHLC_01506	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PHPPBHLC_01507	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHPPBHLC_01508	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHPPBHLC_01509	2.28e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PHPPBHLC_01510	8.5e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHPPBHLC_01511	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHPPBHLC_01512	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PHPPBHLC_01513	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHPPBHLC_01514	3.45e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHPPBHLC_01515	2.11e-161	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
PHPPBHLC_01516	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PHPPBHLC_01517	2.95e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHPPBHLC_01518	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHPPBHLC_01519	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHPPBHLC_01520	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PHPPBHLC_01521	1.46e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHPPBHLC_01522	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHPPBHLC_01523	4.88e-300	-	-	-	L	-	-	-	Transposase
PHPPBHLC_01524	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01525	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
PHPPBHLC_01526	5.71e-203	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01527	1.66e-147	-	-	-	-	-	-	-	-
PHPPBHLC_01528	1.35e-182	-	-	-	G	-	-	-	MucBP domain
PHPPBHLC_01529	2.59e-129	-	-	-	S	-	-	-	Pfam:DUF3816
PHPPBHLC_01530	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PHPPBHLC_01531	1.38e-37	-	-	-	-	-	-	-	-
PHPPBHLC_01532	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PHPPBHLC_01533	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHPPBHLC_01534	4.43e-291	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PHPPBHLC_01535	4.82e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PHPPBHLC_01536	6.57e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHPPBHLC_01537	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PHPPBHLC_01538	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01539	1.21e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PHPPBHLC_01540	2.74e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHPPBHLC_01541	6.2e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHPPBHLC_01542	4.82e-294	-	-	-	V	-	-	-	MatE
PHPPBHLC_01543	0.0	potE	-	-	E	-	-	-	Amino Acid
PHPPBHLC_01544	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHPPBHLC_01545	5.62e-155	csrR	-	-	K	-	-	-	response regulator
PHPPBHLC_01546	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PHPPBHLC_01547	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PHPPBHLC_01548	2.45e-267	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PHPPBHLC_01549	1.29e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
PHPPBHLC_01550	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHPPBHLC_01551	4.91e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PHPPBHLC_01552	1.2e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHPPBHLC_01553	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PHPPBHLC_01554	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PHPPBHLC_01555	3.85e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PHPPBHLC_01556	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHPPBHLC_01557	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PHPPBHLC_01558	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHPPBHLC_01559	1.66e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PHPPBHLC_01560	1.04e-278	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PHPPBHLC_01561	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHPPBHLC_01562	7.5e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHPPBHLC_01563	9.55e-205	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHPPBHLC_01564	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHPPBHLC_01565	5.87e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PHPPBHLC_01566	2.17e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PHPPBHLC_01567	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PHPPBHLC_01568	6.65e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHPPBHLC_01569	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
PHPPBHLC_01570	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
PHPPBHLC_01571	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PHPPBHLC_01572	1.57e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PHPPBHLC_01573	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PHPPBHLC_01574	0.0	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
PHPPBHLC_01575	4.53e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHPPBHLC_01576	2.82e-280	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PHPPBHLC_01577	3.28e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01578	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PHPPBHLC_01580	1.22e-177	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHPPBHLC_01581	0.0	yhaN	-	-	L	-	-	-	AAA domain
PHPPBHLC_01582	1.77e-280	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PHPPBHLC_01583	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PHPPBHLC_01584	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PHPPBHLC_01585	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PHPPBHLC_01586	6.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PHPPBHLC_01587	9.95e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PHPPBHLC_01589	1.49e-54	-	-	-	-	-	-	-	-
PHPPBHLC_01590	4.61e-61	-	-	-	-	-	-	-	-
PHPPBHLC_01591	8.62e-273	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
PHPPBHLC_01592	9.56e-133	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
PHPPBHLC_01593	1.32e-290	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PHPPBHLC_01594	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
PHPPBHLC_01595	6.21e-119	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PHPPBHLC_01596	4.8e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PHPPBHLC_01597	5.39e-92	-	-	-	-	-	-	-	-
PHPPBHLC_01599	9.17e-59	-	-	-	-	-	-	-	-
PHPPBHLC_01600	5.21e-154	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PHPPBHLC_01601	1.52e-43	-	-	-	-	-	-	-	-
PHPPBHLC_01602	8.45e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHPPBHLC_01603	2.41e-236	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PHPPBHLC_01604	5.33e-147	-	-	-	-	-	-	-	-
PHPPBHLC_01605	6.18e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PHPPBHLC_01606	1.26e-230	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PHPPBHLC_01607	5.35e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PHPPBHLC_01608	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PHPPBHLC_01609	2.91e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHPPBHLC_01610	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PHPPBHLC_01611	1.2e-54	-	-	-	-	-	-	-	-
PHPPBHLC_01612	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PHPPBHLC_01613	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHPPBHLC_01614	6.34e-121	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PHPPBHLC_01615	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_01616	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PHPPBHLC_01617	2.24e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PHPPBHLC_01618	6.81e-134	-	-	-	V	-	-	-	VanZ like family
PHPPBHLC_01619	7.03e-33	-	-	-	-	-	-	-	-
PHPPBHLC_01620	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PHPPBHLC_01621	7.91e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PHPPBHLC_01622	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
PHPPBHLC_01623	4.45e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PHPPBHLC_01624	6.12e-195	yeaE	-	-	S	-	-	-	Aldo keto
PHPPBHLC_01625	3.25e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
PHPPBHLC_01626	2.31e-297	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PHPPBHLC_01627	5.95e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PHPPBHLC_01628	2.66e-138	-	-	-	M	-	-	-	LysM domain protein
PHPPBHLC_01629	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
PHPPBHLC_01630	5.32e-140	-	-	-	M	-	-	-	LysM domain protein
PHPPBHLC_01631	1.91e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
PHPPBHLC_01632	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHPPBHLC_01633	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PHPPBHLC_01634	5.43e-311	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PHPPBHLC_01635	1.22e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHPPBHLC_01636	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PHPPBHLC_01637	1.82e-86	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PHPPBHLC_01646	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01647	4.32e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PHPPBHLC_01648	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHPPBHLC_01649	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHPPBHLC_01650	1.13e-219	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHPPBHLC_01651	2.13e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHPPBHLC_01652	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PHPPBHLC_01653	1.24e-182	-	-	-	K	-	-	-	LysR substrate binding domain
PHPPBHLC_01654	8.18e-70	-	-	-	S	-	-	-	branched-chain amino acid
PHPPBHLC_01655	8.37e-187	-	-	-	E	-	-	-	AzlC protein
PHPPBHLC_01656	3.73e-264	hpk31	-	-	T	-	-	-	Histidine kinase
PHPPBHLC_01657	9.76e-161	vanR	-	-	K	-	-	-	response regulator
PHPPBHLC_01658	7.28e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHPPBHLC_01659	2.03e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
PHPPBHLC_01660	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PHPPBHLC_01661	4.73e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
PHPPBHLC_01662	3.97e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PHPPBHLC_01663	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PHPPBHLC_01664	2.57e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PHPPBHLC_01665	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHPPBHLC_01666	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PHPPBHLC_01667	3.26e-196	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PHPPBHLC_01668	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PHPPBHLC_01669	2.93e-197	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PHPPBHLC_01670	1.88e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PHPPBHLC_01671	7.26e-209	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
PHPPBHLC_01672	2.47e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PHPPBHLC_01673	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
PHPPBHLC_01674	4.55e-288	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PHPPBHLC_01675	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01676	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHPPBHLC_01677	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHPPBHLC_01678	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PHPPBHLC_01679	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PHPPBHLC_01680	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PHPPBHLC_01681	9.77e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHPPBHLC_01682	1.81e-275	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PHPPBHLC_01683	1.87e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PHPPBHLC_01684	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHPPBHLC_01685	3.14e-231	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
PHPPBHLC_01686	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PHPPBHLC_01687	1.15e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PHPPBHLC_01688	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PHPPBHLC_01689	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PHPPBHLC_01690	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHPPBHLC_01691	0.0	-	-	-	M	-	-	-	domain protein
PHPPBHLC_01692	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
PHPPBHLC_01693	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PHPPBHLC_01694	9.59e-92	-	-	-	-	-	-	-	-
PHPPBHLC_01696	1.28e-18	-	-	-	-	-	-	-	-
PHPPBHLC_01697	6.37e-278	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHPPBHLC_01698	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHPPBHLC_01699	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PHPPBHLC_01700	1.61e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHPPBHLC_01701	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PHPPBHLC_01702	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PHPPBHLC_01703	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PHPPBHLC_01704	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PHPPBHLC_01705	2.79e-146	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PHPPBHLC_01706	2.68e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHPPBHLC_01707	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PHPPBHLC_01708	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PHPPBHLC_01709	0.0	-	-	-	S	-	-	-	membrane
PHPPBHLC_01710	5.43e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PHPPBHLC_01711	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHPPBHLC_01712	8.38e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PHPPBHLC_01713	1.02e-149	-	-	-	M	-	-	-	PFAM NLP P60 protein
PHPPBHLC_01714	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHPPBHLC_01715	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHPPBHLC_01716	8.23e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHPPBHLC_01717	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PHPPBHLC_01718	6.64e-187	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHPPBHLC_01719	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01720	1.39e-196	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PHPPBHLC_01721	8.11e-131	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHPPBHLC_01722	1.27e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PHPPBHLC_01723	4.87e-203	-	-	-	-	-	-	-	-
PHPPBHLC_01724	1.56e-234	-	-	-	-	-	-	-	-
PHPPBHLC_01725	3.46e-115	-	-	-	S	-	-	-	Protein conserved in bacteria
PHPPBHLC_01728	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
PHPPBHLC_01729	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PHPPBHLC_01730	5.08e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PHPPBHLC_01731	4.17e-60	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PHPPBHLC_01732	1.29e-168	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PHPPBHLC_01733	1.34e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PHPPBHLC_01734	4.63e-152	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
PHPPBHLC_01735	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PHPPBHLC_01736	4.51e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHPPBHLC_01737	1.13e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHPPBHLC_01738	1.81e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHPPBHLC_01739	9.86e-59	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHPPBHLC_01740	8.12e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PHPPBHLC_01741	6.89e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PHPPBHLC_01742	1.11e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PHPPBHLC_01743	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PHPPBHLC_01744	9e-72	-	-	-	-	-	-	-	-
PHPPBHLC_01745	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PHPPBHLC_01746	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHPPBHLC_01747	4.64e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHPPBHLC_01748	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHPPBHLC_01749	2.47e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHPPBHLC_01750	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PHPPBHLC_01751	1.05e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PHPPBHLC_01752	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PHPPBHLC_01753	2.96e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHPPBHLC_01754	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PHPPBHLC_01755	1.06e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PHPPBHLC_01756	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PHPPBHLC_01757	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PHPPBHLC_01758	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PHPPBHLC_01759	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHPPBHLC_01760	1.92e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHPPBHLC_01761	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHPPBHLC_01762	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHPPBHLC_01763	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PHPPBHLC_01764	1.61e-259	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHPPBHLC_01765	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHPPBHLC_01766	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHPPBHLC_01767	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PHPPBHLC_01768	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PHPPBHLC_01769	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHPPBHLC_01770	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PHPPBHLC_01771	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
PHPPBHLC_01772	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHPPBHLC_01773	6.23e-197	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHPPBHLC_01774	2.75e-57	-	-	-	-	-	-	-	-
PHPPBHLC_01776	5.16e-225	-	-	-	-	-	-	-	-
PHPPBHLC_01777	6.18e-63	-	-	-	L	-	-	-	nuclease
PHPPBHLC_01778	5.87e-27	-	-	-	-	-	-	-	-
PHPPBHLC_01781	1.28e-46	-	-	-	-	-	-	-	-
PHPPBHLC_01782	5.01e-69	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
PHPPBHLC_01783	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PHPPBHLC_01784	4.45e-109	-	-	-	-	-	-	-	-
PHPPBHLC_01785	2.84e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PHPPBHLC_01786	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PHPPBHLC_01787	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PHPPBHLC_01788	5.74e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHPPBHLC_01789	3.35e-228	-	-	-	-	-	-	-	-
PHPPBHLC_01790	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHPPBHLC_01791	1.66e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PHPPBHLC_01792	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PHPPBHLC_01793	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PHPPBHLC_01794	3.62e-246	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PHPPBHLC_01795	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHPPBHLC_01796	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHPPBHLC_01797	1.56e-160	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHPPBHLC_01798	7.48e-49	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHPPBHLC_01799	3.96e-165	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PHPPBHLC_01800	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHPPBHLC_01801	6.53e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHPPBHLC_01802	8.95e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHPPBHLC_01803	9.38e-168	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
PHPPBHLC_01804	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PHPPBHLC_01805	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PHPPBHLC_01806	1.5e-220	ydbI	-	-	K	-	-	-	AI-2E family transporter
PHPPBHLC_01807	1.54e-293	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PHPPBHLC_01808	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01810	7.72e-260	-	-	-	-	-	-	-	-
PHPPBHLC_01811	9.06e-195	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PHPPBHLC_01812	8.65e-162	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHPPBHLC_01813	3.38e-132	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PHPPBHLC_01814	1.5e-91	-	-	-	-	-	-	-	-
PHPPBHLC_01815	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PHPPBHLC_01816	1.02e-135	-	-	-	L	-	-	-	nuclease
PHPPBHLC_01817	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PHPPBHLC_01818	7.54e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PHPPBHLC_01819	4.82e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PHPPBHLC_01820	3.4e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PHPPBHLC_01822	4.74e-51	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
PHPPBHLC_01823	1.71e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
PHPPBHLC_01825	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PHPPBHLC_01826	2.66e-219	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PHPPBHLC_01828	1.27e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
PHPPBHLC_01830	5.82e-57	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHPPBHLC_01831	1.15e-34	-	-	-	-	-	-	-	-
PHPPBHLC_01833	3.71e-57	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
PHPPBHLC_01835	8.62e-150	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
PHPPBHLC_01836	2.36e-306	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
PHPPBHLC_01837	1.43e-209	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PHPPBHLC_01838	5.66e-128	-	-	-	K	-	-	-	UTRA
PHPPBHLC_01839	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
PHPPBHLC_01840	3.46e-124	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PHPPBHLC_01841	2.08e-82	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PHPPBHLC_01842	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHPPBHLC_01843	9.64e-141	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PHPPBHLC_01844	8.17e-208	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHPPBHLC_01845	1.02e-160	-	-	-	S	-	-	-	polysaccharide biosynthetic process
PHPPBHLC_01846	4.54e-38	-	-	-	-	-	-	-	-
PHPPBHLC_01847	4.46e-55	cps1B	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
PHPPBHLC_01849	6.03e-83	-	-	-	-	-	-	-	-
PHPPBHLC_01850	1.15e-60	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PHPPBHLC_01851	1.26e-66	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
PHPPBHLC_01852	5.04e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PHPPBHLC_01853	2.03e-193	epsB	-	-	M	-	-	-	biosynthesis protein
PHPPBHLC_01854	8.54e-223	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PHPPBHLC_01855	2.66e-88	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHPPBHLC_01856	3.14e-167	-	-	-	-	-	-	-	-
PHPPBHLC_01857	4.08e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PHPPBHLC_01858	1.33e-47	-	-	-	-	-	-	-	-
PHPPBHLC_01859	1.16e-108	-	-	-	-	-	-	-	-
PHPPBHLC_01860	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHPPBHLC_01861	1.1e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PHPPBHLC_01862	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PHPPBHLC_01863	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHPPBHLC_01869	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PHPPBHLC_01870	1.15e-196	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PHPPBHLC_01873	1.38e-139	-	-	-	-	-	-	-	-
PHPPBHLC_01874	2.68e-316	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_01875	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
PHPPBHLC_01876	2.04e-167	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PHPPBHLC_01877	5.03e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PHPPBHLC_01878	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHPPBHLC_01879	4.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHPPBHLC_01880	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PHPPBHLC_01881	2.25e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PHPPBHLC_01883	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
PHPPBHLC_01884	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PHPPBHLC_01885	1.1e-136	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PHPPBHLC_01886	3.59e-81	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PHPPBHLC_01887	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PHPPBHLC_01888	3.87e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PHPPBHLC_01889	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PHPPBHLC_01890	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHPPBHLC_01891	1.27e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PHPPBHLC_01892	2.58e-275	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PHPPBHLC_01893	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHPPBHLC_01894	5.84e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHPPBHLC_01895	1.67e-178	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PHPPBHLC_01896	1.02e-77	gmT1	-	-	EG	-	-	-	EamA-like transporter family
PHPPBHLC_01897	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PHPPBHLC_01898	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHPPBHLC_01899	6.72e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PHPPBHLC_01900	4.86e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PHPPBHLC_01901	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHPPBHLC_01902	5.12e-266	yacL	-	-	S	-	-	-	domain protein
PHPPBHLC_01903	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PHPPBHLC_01904	2.16e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHPPBHLC_01905	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHPPBHLC_01906	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PHPPBHLC_01907	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHPPBHLC_01908	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PHPPBHLC_01909	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHPPBHLC_01910	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHPPBHLC_01911	5.57e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
PHPPBHLC_01913	8.02e-313	-	-	-	M	-	-	-	Glycosyl transferase family group 2
PHPPBHLC_01914	1.26e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHPPBHLC_01915	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHPPBHLC_01916	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHPPBHLC_01917	2.39e-64	-	-	-	-	-	-	-	-
PHPPBHLC_01919	1.2e-64	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHPPBHLC_01920	1.61e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
PHPPBHLC_01921	1.36e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
PHPPBHLC_01922	7.63e-169	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PHPPBHLC_01923	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
PHPPBHLC_01924	1.15e-269	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PHPPBHLC_01925	7.92e-20	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PHPPBHLC_01926	0.0	-	-	-	M	-	-	-	NlpC/P60 family
PHPPBHLC_01927	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHPPBHLC_01928	3.09e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PHPPBHLC_01929	3.74e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
PHPPBHLC_01930	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
PHPPBHLC_01931	1.06e-198	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PHPPBHLC_01932	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHPPBHLC_01933	7.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PHPPBHLC_01934	8.17e-208	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHPPBHLC_01935	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PHPPBHLC_01937	1.79e-169	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PHPPBHLC_01939	1.63e-92	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PHPPBHLC_01940	9.25e-12	-	-	-	-	-	-	-	-
PHPPBHLC_01941	1.24e-112	-	-	-	S	-	-	-	Glycosyltransferase like family
PHPPBHLC_01942	9.12e-111	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PHPPBHLC_01943	3.35e-53	-	-	-	M	-	-	-	biosynthesis protein
PHPPBHLC_01944	1.09e-116	cps3F	-	-	-	-	-	-	-
PHPPBHLC_01945	2.18e-129	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PHPPBHLC_01946	7.32e-140	-	-	-	S	-	-	-	Glycosyltransferase like family 2
PHPPBHLC_01947	8.11e-97	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
PHPPBHLC_01948	9.79e-272	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PHPPBHLC_01949	3.02e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PHPPBHLC_01950	3.89e-47	-	-	-	-	-	-	-	-
PHPPBHLC_01951	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
PHPPBHLC_01952	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
PHPPBHLC_01953	5.79e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PHPPBHLC_01954	1.29e-145	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PHPPBHLC_01955	2.44e-127	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PHPPBHLC_01956	5.17e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PHPPBHLC_01957	2.53e-42	-	-	-	-	-	-	-	-
PHPPBHLC_01958	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PHPPBHLC_01959	2.05e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PHPPBHLC_01960	0.0	potE	-	-	E	-	-	-	Amino Acid
PHPPBHLC_01961	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PHPPBHLC_01962	2.3e-279	arcT	-	-	E	-	-	-	Aminotransferase
PHPPBHLC_01963	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PHPPBHLC_01964	2.72e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PHPPBHLC_01965	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
PHPPBHLC_01966	1.02e-24	-	-	-	-	-	-	-	-
PHPPBHLC_01967	1.43e-26	-	-	-	-	-	-	-	-
PHPPBHLC_01968	5.74e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHPPBHLC_01970	9.46e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PHPPBHLC_01971	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
PHPPBHLC_01972	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PHPPBHLC_01973	2.87e-143	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PHPPBHLC_01974	2.64e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PHPPBHLC_01975	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PHPPBHLC_01976	7.71e-256	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
PHPPBHLC_01977	2.73e-106	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
PHPPBHLC_01978	1.07e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PHPPBHLC_01979	8.49e-266	-	-	-	P	-	-	-	Major Facilitator Superfamily
PHPPBHLC_01980	2.9e-26	-	-	-	-	-	-	-	-
PHPPBHLC_01981	1.49e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
PHPPBHLC_01982	6.48e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PHPPBHLC_01983	2.36e-216	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
PHPPBHLC_01984	4.59e-93	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PHPPBHLC_01985	2.68e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PHPPBHLC_01986	2.54e-101	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PHPPBHLC_01987	2.42e-38	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
PHPPBHLC_01988	6.17e-158	pnb	-	-	C	-	-	-	nitroreductase
PHPPBHLC_01989	8.3e-117	-	-	-	-	-	-	-	-
PHPPBHLC_01990	5.75e-115	XK27_07210	-	-	S	-	-	-	B3 4 domain
PHPPBHLC_01991	1.32e-315	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
PHPPBHLC_01992	8.89e-269	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PHPPBHLC_01993	1.19e-111	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PHPPBHLC_01994	1.96e-64	-	-	-	-	-	-	-	-
PHPPBHLC_01995	7.92e-250	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PHPPBHLC_01996	1.53e-77	-	-	-	H	-	-	-	Riboflavin biosynthesis protein RibD
PHPPBHLC_01997	3.81e-218	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
PHPPBHLC_01999	2.92e-107	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PHPPBHLC_02000	2.84e-313	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_02001	2.02e-138	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PHPPBHLC_02002	2.12e-114	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHPPBHLC_02003	9.51e-114	entB	-	-	Q	-	-	-	Isochorismatase family
PHPPBHLC_02004	1.08e-83	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PHPPBHLC_02005	1.5e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
PHPPBHLC_02006	9.45e-266	-	-	-	EGP	-	-	-	Major Facilitator
PHPPBHLC_02007	6.4e-59	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHPPBHLC_02008	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHPPBHLC_02010	4.7e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PHPPBHLC_02011	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHPPBHLC_02012	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHPPBHLC_02013	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHPPBHLC_02014	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
PHPPBHLC_02015	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHPPBHLC_02016	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PHPPBHLC_02017	3.63e-269	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PHPPBHLC_02018	1.36e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHPPBHLC_02019	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PHPPBHLC_02020	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
PHPPBHLC_02021	3.88e-186	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902